ascorbic-acid and Flushing

ascorbic-acid has been researched along with Flushing* in 1 studies

Trials

1 trial(s) available for ascorbic-acid and Flushing

Article	Year
Primary Sjögren's syndrome treated with Efamol/Efavit. A double-blind cross-over investigation. Rheumatology international, 1984, Volume: 4, Issue:4 Thirty-six patients with primary Sjögren's syndrome participated in a randomised double-blind, cross-over, 3-week, study to compare the effect of Efamol (1500 mg X 2) with that of placebo. Efamol contains 9% of the prostaglandin-E1 precursor gamma-linolenic acid, which is presumed to occur in reduced levels in Sjögren's syndrome. Efamol treatment improved the Schirmer-I-test (P less than 0.03) while values of break-up time,-van Bijsterveld score, corneasensitivity, tear-lysozyme and nuclear chromatin in conjunctival epithelial cells did not reach the statistical 0.05 level. Topics: Adult; Aged; Ascorbic Acid; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Fatty Acids, Essential; Fatty Acids, Unsaturated; Female; Flushing; gamma-Linolenic Acid; Humans; Linoleic Acids; Male; Middle Aged; Niacin; Oenothera biennis; Plant Oils; Pyridoxine; Sjogren's Syndrome; Zinc; Zinc Compounds	1984

Article

Year

Primary Sjögren's syndrome treated with Efamol/Efavit. A double-blind cross-over investigation.

Rheumatology international, 1984, Volume: 4, Issue:4

Thirty-six patients with primary Sjögren's syndrome participated in a randomised double-blind, cross-over, 3-week, study to compare the effect of Efamol (1500 mg X 2) with that of placebo. Efamol contains 9% of the prostaglandin-E1 precursor gamma-linolenic acid, which is presumed to occur in reduced levels in Sjögren's syndrome. Efamol treatment improved the Schirmer-I-test (P less than 0.03) while values of break-up time,-van Bijsterveld score, corneasensitivity, tear-lysozyme and nuclear chromatin in conjunctival epithelial cells did not reach the statistical 0.05 level.

Topics: Adult; Aged; Ascorbic Acid; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Fatty Acids, Essential; Fatty Acids, Unsaturated; Female; Flushing; gamma-Linolenic Acid; Humans; Linoleic Acids; Male; Middle Aged; Niacin; Oenothera biennis; Plant Oils; Pyridoxine; Sjogren's Syndrome; Zinc; Zinc Compounds

1984