ascorbic-acid and Exanthema

Topics: Alcoholism; Anorexia; Ascorbic Acid; Diagnosis, Differential; Early Diagnosis; Erythrocyte Transfusion; Exanthema; Fatigue; Gingival Hypertrophy; Hematoma; Humans; Lethargy; Male; Middle Aged; Muscle Weakness; Prognosis; Risk Factors; Scurvy

Topics: Adult; Aged; Ascorbic Acid; Drug Eruptions; Drug Hypersensitivity; Eczema; Erythema Nodosum; Exanthema; Female; Humans; Lymphocyte Activation; Male; Medical History Taking; Middle Aged; Occupational Diseases; Penicillins; Photosensitivity Disorders; Pyridoxine; Radioallergosorbent Test; Skin Diseases; Stevens-Johnson Syndrome; Sulfonamides; Surveys and Questionnaires

We report a case of a man in his 60s who developed pulmonary arterial hypertension (PAH) in association with profound vitamin C deficiency. Decreased availability of endothelial nitric oxide and activation of the hypoxia-inducible family of transcription factors, both consequences of vitamin C deficiency, are believed to be mechanisms contributing to the pathogenesis of the pulmonary hypertension. The PAH resolved following vitamin C supplementation. The current case highlights the importance of testing for vitamin C deficiency in patients with PAH in the proper clinical setting.

Topics: Aged; Anemia; Arthralgia; Ascorbic Acid; Ascorbic Acid Deficiency; Cardiac Catheterization; Echocardiography; Endothelium, Vascular; Exanthema; Humans; Hypoxia; Male; Nitric Oxide; Pulmonary Arterial Hypertension; Transcription Factors; Vitamins

Scurvy is a rare disease in developed nations. In the field of pediatrics, it primarily is seen in children with developmental and behavioral issues, malabsorptive processes, or diseases involving dysphagia. We present the case of an otherwise developmentally appropriate 4-year-old boy who developed scurvy after gradual self-restriction of his diet. He initially presented with a limp and a rash and was subsequently found to have anemia and hematuria. A serum vitamin C level was undetectable, and after review of the MRI of his lower extremities, the clinical findings supported a diagnosis of scurvy. Although scurvy is rare in developed nations, this diagnosis should be considered in a patient with the clinical constellation of lower-extremity pain or arthralgias, a nonblanching rash, easy bleeding or bruising, fatigue, and anemia. This case highlights the importance of carefully assessing a child's dietary and developmental status at well-child visits, which can help avoid a more invasive workup.

Topics: Anemia, Iron-Deficiency; Ascorbic Acid; Child, Preschool; Diet; Exanthema; Hematuria; Humans; Lower Extremity; Magnetic Resonance Imaging; Male; Scurvy; Vitamin D Deficiency

Topics: Adolescent; Arthralgia; Ascorbic Acid; Autistic Disorder; Diagnosis, Differential; Exanthema; Humans; Male; Scurvy

Topics: Ascorbic Acid; Ascorbic Acid Deficiency; Exanthema; Humans; Male; Middle Aged; Muscle Weakness

Topics: Ascorbic Acid; Exanthema; Fluid Therapy; Gingival Hemorrhage; Humans; Immobilization; Male; Malnutrition; Middle Aged; Scurvy; Social Isolation; Thiamine; Treatment Outcome; Vitamins

Topics: Ascorbic Acid; Autistic Disorder; Bone and Bones; Bone Marrow; Child; Diagnosis, Differential; Exanthema; Gingival Hypertrophy; Humans; Male; Osteomyelitis; Pain; Radiography; Rheumatic Diseases; Scurvy; Skin

Topics: Ascorbic Acid; Deglutition Disorders; Exanthema; HIV Infections; Humans; Male; Middle Aged; Scurvy; Vitamins

Topics: Ascorbic Acid; Citrus sinensis; Exanthema; Flavoring Agents; Humans; Mothers; Vitamins