ascorbic-acid and Eczema

Topics: Adult; Aged; Ascorbic Acid; Drug Eruptions; Drug Hypersensitivity; Eczema; Erythema Nodosum; Exanthema; Female; Humans; Lymphocyte Activation; Male; Medical History Taking; Middle Aged; Occupational Diseases; Penicillins; Photosensitivity Disorders; Pyridoxine; Radioallergosorbent Test; Skin Diseases; Stevens-Johnson Syndrome; Sulfonamides; Surveys and Questionnaires

Antioxidant intakes in pregnancy may influence fetal immune programming and the risk of allergic disease. We investigated associations between maternal intakes of β-carotene, vitamin C, vitamin E, copper and zinc, and infant allergic outcomes. Antioxidant intakes of pregnant women (n = 420) assessed prospectively by a food frequency questionnaire, were examined in relation to allergic outcomes at 1 year of age (n = 300). The main relationships with allergic outcomes were seen with dietary vitamin C and copper. Specifically, higher maternal dietary vitamin C intake was associated with a reduced risk of any diagnosed infant allergic disease and wheeze. After adjustment for potential confounders the relationship with wheeze remained statistically significant. There was also an inverse linear relationship between vitamin C and food allergy. Higher dietary copper intake was associated with reduced risk of eczema, wheeze and any allergic disease. The relationship with wheeze and any allergic disease remained statistically significant in multivariate analysis, and there was also an inverse linear relationship between copper and food allergy. However, these relationships were only seen for nutrients present in food. There were no relationships between β-carotene, vitamin E or zinc and any allergic outcomes. In summary, this study suggests that maternal diet of fresh foods rich in vitamin C is associated with reduced risk of infant wheeze, and that copper intake is associated with reduced risk of several allergic outcomes.

Topics: Antioxidants; Ascorbic Acid; beta Carotene; Copper; Diet; Dietary Supplements; Eczema; Female; Fish Oils; Food Hypersensitivity; Humans; Hypersensitivity; Immunoglobulin E; Infant; Infant, Newborn; Maternal Nutritional Physiological Phenomena; Maternal-Fetal Exchange; Pregnancy; Prenatal Exposure Delayed Effects; Prospective Studies; Ubiquitin-Protein Ligases; Vitamin E

Topics: Adult; Aged; Ascorbic Acid; Baths; Chlorine; Eczema; Female; Humans; Male; Middle Aged; Pilot Projects; Vitamins; Water; Water Purification; Water Supply

Topics: Ascorbic Acid; Dose-Response Relationship, Drug; Eczema; Humans; Leg Ulcer; Treatment Outcome

Two thousand women were recruited for a prospective investigation of the influence of maternal antioxidant intake in pregnancy on the development of asthma and eczema in children. A food frequency questionnaire was used to characterize diet during pregnancy and blood antioxidant levels were measured. Postal questionnaires were used to follow up the 1,924 singleton children born to the cohort at 6, 12, and 24 months of age. There were no associations between maternal antioxidant intake and wheezing symptoms and eczema in the children's first year. In the children's second year, maternal vitamin E intake during pregnancy was negatively associated with wheeze in the absence of a "cold" (p for trend 0.010) and, in children whose mothers were atopic, there was a negative association between maternal vitamin E intake and childhood eczema (p for trend 0.024). Maternal vitamin C intake during pregnancy was positively associated with "ever wheeze" and eczema during the children's second year. This study suggests that maternal dietary antioxidant intakes during pregnancy may modify the risks of developing wheeze and eczema during early childhood. Further follow up of the cohort will determine whether maternal diet during pregnancy is associated with asthma and atopic disease in later childhood.

Topics: Adult; Antioxidants; Ascorbic Acid; Asthma; Dermatitis, Atopic; Diet; Eczema; Female; Humans; Infant; Infant, Newborn; Logistic Models; Multivariate Analysis; Pregnancy; Prenatal Care; Prevalence; Prospective Studies; Respiratory Sounds; United Kingdom; Vitamin E

Topics: Adult; Aged; Ascorbic Acid; Eczema; Family Practice; Female; Herpes Simplex; Herpes Zoster; Humans; Male; Orthomolecular Therapy

A case of vitamin C allergy of the delayed type is reported. Eczematous skin lesions appeared during normal uptake of the vitamin C contained in food. After a vitamin C-free diet, the skin lesions disappeared. Patch tests and an oral exposure with vitamin C gave positive reactions. This observation of vitamin C allergy is compared with previous published cases.

Topics: Ascorbic Acid; Dermatitis, Contact; Eczema; Fluocortolone; Humans; Male; Middle Aged

Topics: Adult; Aged; Ascorbic Acid; Copper; Eczema; Female; Humans; Male; Manganese; Middle Aged; Thiamine; Trace Elements; Vitamin A; Vitamins; Zinc

Topics: Adult; Aged; Ascorbic Acid; Blood Proteins; Carbohydrate Metabolism; Copper; Eczema; Female; Fructose; Hexoses; Humans; Male; Metabolic Diseases; Middle Aged; Pentoses; Protein Binding; Pyruvates; Thiamine

Topics: Adult; Aged; Alanine Transaminase; Ascorbic Acid; Aspartate Aminotransferases; Eczema; Female; Humans; Male; Middle Aged; Thiamine; Vitamin A; Vitamins

Topics: Administration, Topical; Ascorbic Acid; Digitalis; Eczema; Follow-Up Studies; Humans; Infant; Male; Methemoglobinemia; Oxygen Inhalation Therapy; Phenols; Phytotherapy; Plants, Medicinal; Plants, Toxic; Resorcinols; Solutions

Topics: Ascorbic Acid; Chromates; Dermatitis; Dermatitis, Contact; Dermatitis, Occupational; Eczema; Edetic Acid; Female; Humans; Ion Exchange; Male; Ointments; Skin Tests; Switzerland

Topics: Adolescent; Adult; Aged; Ascorbic Acid; Blood Transfusion, Autologous; Desensitization, Immunologic; Eczema; Female; Humans; Male; Middle Aged; Physical Therapy Modalities; Prednisolone; Thiamine; Tranquilizing Agents

Topics: Adrenal Cortex Hormones; Adult; Ascorbic Acid; Eczema; Female; Humans; Male; Middle Aged; Niacinamide; Porphyrias; Prurigo; Vitamin B Complex

Topics: Adolescent; Adult; Aged; Ascorbic Acid; Chronic Disease; Copper; Eczema; Female; Humans; Male; Middle Aged

Topics: Adolescent; Adult; Ascorbic Acid; Child; Copper; Eczema; Female; Humans; Male; Middle Aged; Thiamine

Topics: Adult; Ampicillin; Ascorbic Acid; Biopsy; Eczema; Female; Folic Acid; Foot Dermatoses; Hand Dermatoses; Humans; Jejunum; Male; Singapore; Sprue, Tropical; Xylose

Topics: Adult; Ascorbic Acid; Chronic Disease; Copper; Eczema; Humans; Middle Aged

Topics: Adolescent; Adult; Ascorbic Acid; Child; Eczema; Female; Humans; Male; Middle Aged; Pyruvates; Thiamine

Topics: Ascorbic Acid; Child, Preschool; Eczema; Humans; Infant; Pyridoxine; Thiamine; Vitamins

Topics: Acne Vulgaris; Adolescent; Amino Acids; Ascorbic Acid; Dermatitis; Dermatitis, Contact; Dermatology; Drug Eruptions; Eczema; Erythema; Glutamates; Melanosis; Neurodermatitis; Pantothenic Acid; Polyarteritis Nodosa; Psoriasis; Tablets; Tiopronin; Toxicology; Urticaria

Topics: Arsenic; Ascorbic Acid; Diagnosis, Differential; Drug Therapy; Eczema; Egypt; Hemosiderosis; Histamine H1 Antagonists; Humans; Pathology; Pruritus; Purpura

Topics: Ascorbic Acid; Biomedical Research; Eczema; Humans; Industry; Occupational Health; Ointments; Vitamins