ascorbic-acid and Ecchymosis

Topics: Alcoholism; Ascorbic Acid; Ecchymosis; Foot; Humans; Leg; Male; Middle Aged; Purpura; Scurvy; Vitamins

A 58-year-old woman presented with a 1-week history of lower limb bruising. She had a medical history of recurrent metastatic colon cancer with a sigmoid colectomy and complete pelvic exenteration leading to colostomy and urostomy formation. She had malignant sacral mass encroaching on the spinal cord. This caused a left-sided foot drop for which she used an ankle-foot orthosis. She was on cetuximab and had received radiotherapy to the sacral mass 1 month ago. On examination, there were macular ecchymoses with petechiae on the lower limbs. There was sparing of areas that had been compressed by the ankle-foot orthosis. Bloods showed mild thrombocytopaenia and anaemia with markedly raised inflammatory markers. Coagulation studies consistent with inflammation rather than disseminated intravascular coagulation. She was found to have

Topics: Antineoplastic Agents, Immunological; Ascorbic Acid; Bacteremia; Colectomy; Colorectal Neoplasms; Diagnosis, Differential; Ecchymosis; Female; Humans; Klebsiella; Lower Extremity; Malnutrition; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Nutritional Support; Pelvic Exenteration; Scurvy; Skin; Treatment Outcome; Vitamins

Topics: Aged; Ascorbic Acid; Ecchymosis; Humans; Leg Dermatoses; Male; Scurvy

Topics: Aged; Ascorbic Acid; Ecchymosis; Gingival Hemorrhage; Humans; Male; Scurvy; Vitamins

Topics: Anemia; Ascorbic Acid; Colonic Diseases; Deglutition Disorders; Ecchymosis; Endoscopy, Gastrointestinal; Female; Gastrointestinal Hemorrhage; Humans; Ileal Diseases; Middle Aged; Rectum; Scurvy; Stomach Diseases

A diet restricted to rice and boiled fruit and vegetables leads to vitamin C deficiency. We describe the third case, to our knowledge, of retinal hemorrhages related to scurvy. Reduced bilateral visual acuity in a 50-year-old patient was associated with macrocytic anemia, denutrition, and cutaneous ecchymoses. Oral vitamin C treatment provided subjective clinical improvement and regression of the retinal hemorrhages on fundus examination, with no side effects. Vitamin C plays an important role in collagen stability in vascular and bone walls.

Topics: Anemia, Macrocytic; Ascorbic Acid; Collagen; Cooking; Diet, Vegetarian; Ecchymosis; Emergencies; Gastritis, Atrophic; Humans; Male; Middle Aged; Retinal Hemorrhage; Scurvy; Vitamin B 12 Deficiency

Topics: Administration, Oral; Aged; Ascorbic Acid; Calcium; Diagnosis, Differential; Ecchymosis; Folic Acid; Follow-Up Studies; Humans; Male; Periodontitis; Scurvy; Time Factors; Treatment Outcome; Vitamin D

Topics: Adult; Ascorbic Acid; Ascorbic Acid Deficiency; Chronic Disease; Colitis, Ulcerative; Diagnosis, Differential; Dietary Proteins; Ecchymosis; Fruit; Gastritis; Humans; Male; Middle Aged; Purpura

The risk of vitamin C deficiency is underestimated in industrialized countries and is only disclosed in rare cases of severe scurvy.. We report three cases of scurvy presenting with ecchymotic purpura and hemorrhagic ulcerations of the lower limbs. Vitamin C supplementation led to rapid improvement of the skin lesions.. Clinical diagnosis of low-grade deficiency can be difficult. Biological diagnosis requires special care in sample taking and transport.

Topics: Aged; Aged, 80 and over; Ascorbic Acid; Ascorbic Acid Deficiency; Diagnosis, Differential; Ecchymosis; Female; Hemorrhage; Humans; Leg Dermatoses; Leg Ulcer; Purpura; Risk Factors; Scurvy

Topics: Adult; Ascorbic Acid; Diet; Ecchymosis; Erythema; Humans; Male; Scurvy; Skin

Topics: Adult; Ascorbic Acid; Ecchymosis; Female; Fluvoxamine; Hemorrhage; Humans; Menorrhagia; Panic Disorder; Paroxetine

We report a 66 years-old man case that was admitted with abdominal wall hemorrhagic swelling ecchymosis on inferior extremities and perifollicular purpura with hyperkeratosis of the follicles, which gives it an appearance of palpable purpura, together with gingival hemorrhage and moderate anemia. He was a well-nourished sick man but who made a peculiar diet, practically free from fruit and vegetables which developed a pure and serious form of scurvy. We report this case because we consider that the features which appear are illustrative to provide the immediate clinical diagnosis of this uncommon disease, potentially mortal, but easy to diagnose, if we think about it in the adequate clinical contexts, and which it is quickly curable with the administration of ascorbic acid.

Topics: Abdominal Muscles; Aged; Ascorbic Acid; Avitaminosis; Ecchymosis; Feeding Behavior; Hematoma; Hemorrhage; Humans; Male; Scurvy

Topics: Ascorbic Acid; Ecchymosis; Female; Fluoxetine; Fluvoxamine; Humans

Topics: Ascorbic Acid; Diagnosis, Differential; Ecchymosis; Humans; Male; Middle Aged; Scurvy

Topics: Aged; Ascorbic Acid; Ecchymosis; Gingivitis; Humans; Leg; Male; Scurvy; Thrombophlebitis

Scurvy occurred in an elderly man with fatigue, dyspnea on exertion, and extensive ecchymoses and brawny edema of the legs. Platelet count, prothrombin time, and partial thromboplastin time were normal, but serum ascorbic acid level was very low. Other signs considered to be classic and almost pathognomonic for were absent: bleeding gums, hyperkeratotic follicles, coiled hairs, and perifollicular hemorrhages. Reliance on these well-known features of scurvy may obscure or delay diagnosis of an easily cured disorder Severe scurvy is most commonly suggested by tenderness, extensive ecchymoses, and brawny edema of the lower extremities.

Topics: Aged; Ascorbic Acid; Diet; Dyspnea; Ecchymosis; Edema; Fatigue; Humans; Male; Mouth, Edentulous; Scurvy

Topics: Aged; Ascorbic Acid; Blood Sedimentation; Depression; Diazepam; Diet; Ecchymosis; Family Practice; Fruit; Hemoglobins; Humans; Imipramine; Leukocyte Count; Male; Prothrombin Time; Scurvy; Urea