ascorbic-acid and Dermatitis--Occupational

Topics: Ascorbic Acid; Chromates; Dermatitis, Contact; Dermatitis, Occupational; Humans; Male; Middle Aged; Ointments; Potassium Dichromate; Technology, Radiologic; Workforce

Firstly we showed the reason for the choice of each product used in the preparation of this cosmetic. After this we studied "in vitro" the effect of this preparation, and "in vivo" in 25 patients sensitive to Potassium dichromate. On seeing the null effect of this preparation, owing to the oxidation of ascorbic acid, on these 25 patients, we modified the formula, substituting the ascorbic acid and EDTA, respectively, for tartaric acid and glycine. The respective tests "in vitro" and "in vivo" on 20 patients, this time showed beneficial effect of this preparation in 60% of the patients tested. Of these 60%, a 25% have continue to work exposed to the allergen (dichromate or nickel) and the other 35% have continue working with lesions controlled by habitual topic therapy. This preparation can also be used, with less effect, for nickel.

Topics: Administration, Topical; Ascorbic Acid; Chromium; Cosmetics; Dermatitis, Contact; Dermatitis, Occupational; Edetic Acid; Humans; Nickel; Silicones

A worker with strong chromium sensitivity was obliged to handle freshly printed paper with inks containing chromium. Because of his importance to the firm, he continued in the position despite a severe hand dermatitis. Gloves and barrier creams were unacceptable, as were oral antihistamines and corticosteroids. A solution of 10% ascorbic acid was applied to his hands at the worksite in order to reduce the active hexavalent chromium to the inactive trivalent form. This inexpensive, easy-to-use method resulted in a speedy recovery and long-term employment of a valued employee.

Topics: Adult; Ascorbic Acid; Chromium; Dermatitis, Occupational; Humans; Ink; Male; Paper

Topics: Ascorbic Acid; Chelating Agents; Chromium; Dermatitis, Atopic; Dermatitis, Occupational; Edetic Acid; Humans; Moscow

Topics: Ascorbic Acid; Chromates; Dermatitis; Dermatitis, Contact; Dermatitis, Occupational; Eczema; Edetic Acid; Female; Humans; Ion Exchange; Male; Ointments; Skin Tests; Switzerland

Topics: Aerosols; Animals; Antidotes; Ascorbic Acid; Chelating Agents; Chromates; Dermatitis; Dermatitis, Occupational; Filtration; Guinea Pigs; Humans; Male; Oxidation-Reduction; Rats; Skin Ulcer; Ventilators, Mechanical