ascorbic-acid and Ataxia-Telangiectasia

ascorbic-acid has been researched along with Ataxia-Telangiectasia* in 2 studies

Reviews

1 review(s) available for ascorbic-acid and Ataxia-Telangiectasia

Article	Year
The phagocytic cell and its disorders. Annals of allergy, 1983, Volume: 51, Issue:3 Topics: Actins; Agammaglobulinemia; Ascorbic Acid; Ataxia Telangiectasia; Blood Transfusion; Cell Adhesion; Cell Membrane; Chemotaxis; Cyclic GMP; Dysgammaglobulinemia; Exocrine Pancreatic Insufficiency; Female; Humans; IgA Deficiency; Immunoglobulin E; Levamisole; Male; Maternal-Fetal Exchange; Membrane Proteins; Microtubules; Myosins; Neutropenia; Phagocyte Bactericidal Dysfunction; Phagocytes; Pregnancy	1983

Article

Year

Annals of allergy, 1983, Volume: 51, Issue:3

Topics: Actins; Agammaglobulinemia; Ascorbic Acid; Ataxia Telangiectasia; Blood Transfusion; Cell Adhesion; Cell Membrane; Chemotaxis; Cyclic GMP; Dysgammaglobulinemia; Exocrine Pancreatic Insufficiency; Female; Humans; IgA Deficiency; Immunoglobulin E; Levamisole; Male; Maternal-Fetal Exchange; Membrane Proteins; Microtubules; Myosins; Neutropenia; Phagocyte Bactericidal Dysfunction; Phagocytes; Pregnancy

1983

Other Studies

1 other study(ies) available for ascorbic-acid and Ataxia-Telangiectasia

Article	Year
Manipulation of Redox Metabolism Using Pharmacologic Ascorbate Opens a Therapeutic Window for Radio-Sensitization by ATM Inhibitors in Colorectal Cancer. International journal of radiation oncology, biology, physics, 2023, 03-15, Volume: 115, Issue:4 Ataxia telangiectasia mutated kinase (ATM) inhibitors are potent radiosensitizers that regulate DNA damage responses and redox metabolism, but they have not been translated clinically because of the potential for excess normal tissue toxicity. Pharmacologic ascorbate (P-AscH. Clonogenic survival was assessed in human (human colon tumor [HCT]116, SW480, HT29) and murine (CT26, MC38) colorectal tumor lines and normal cells (human umbilical vein endothelial cell, FHs74) after radiation ± DNA repair inhibitors ± P-AscH. KU60019 with P-AscH. We provide evidence that redox modulating drugs, such as P-AscH Topics: Animals; Ascorbic Acid; Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line, Tumor; DNA Damage; Humans; Hydrogen Peroxide; Mice; Oxidation-Reduction; Pancreatic Neoplasms; Therapeutic Index	2023

Article

Year

Manipulation of Redox Metabolism Using Pharmacologic Ascorbate Opens a Therapeutic Window for Radio-Sensitization by ATM Inhibitors in Colorectal Cancer.

International journal of radiation oncology, biology, physics, 2023, 03-15, Volume: 115, Issue:4

Ataxia telangiectasia mutated kinase (ATM) inhibitors are potent radiosensitizers that regulate DNA damage responses and redox metabolism, but they have not been translated clinically because of the potential for excess normal tissue toxicity. Pharmacologic ascorbate (P-AscH. Clonogenic survival was assessed in human (human colon tumor [HCT]116, SW480, HT29) and murine (CT26, MC38) colorectal tumor lines and normal cells (human umbilical vein endothelial cell, FHs74) after radiation ± DNA repair inhibitors ± P-AscH. KU60019 with P-AscH. We provide evidence that redox modulating drugs, such as P-AscH

Topics: Animals; Ascorbic Acid; Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line, Tumor; DNA Damage; Humans; Hydrogen Peroxide; Mice; Oxidation-Reduction; Pancreatic Neoplasms; Therapeutic Index

2023