ascorbic-acid and Astigmatism

To analyze remote clinical and functional outcomes of correcting high myopia in patients with thin cornea by the method of femtosecond laser-assisted implantation of intracorneal implant MyoRing.. The study included 22 patients (22 eyes; the mean age of study patients was 30.2±5.37 years). Mean spherical equivalent (SE) of refraction was -11.52±1.96 D, cylindrical component (cyl) of refraction was -2.04±1.64 D, minimal pachymetry index in the center was 491.6±20 µm, corneal hysteresis (CH) amounted to 8.6±1.19 mm Hg. The average pupil diameter in mesopic conditions was 5.6±0.23 mm. All patients had a history of mild amblyopia. The follow-up period lasted 2 years.. Анализ отдаленных клинико-функциональных результатов коррекции миопии высокой степени у пациентов с тонкой роговицей методом интрастромальной имплантации кольца MyoRing с фемтолазерным сопровождением.. В исследование включены 22 пациента (22 глаза; средний возраст пациентов 30,2±5,37 года). До операции среднее значение сфероэквивалента рефракции (СЭ) составило (–)11,52±1,96 дптр, цилиндрического компонента (cyl) — (–)2,04±1,64 дптр, минимальное значение пахиметрии в центре — 491,6±20 мкм, корнеальный гистерезис (КГ) — 8,6±1,19 мм рт.ст. Средний диаметр зрачка в мезопических условиях 5,6±0,23 мм. У всех пациентов в анамнезе имелась амблиопия слабой степени. Срок наблюдения — 2 года.

Topics: Adult; Ascorbic Acid; Astigmatism; Cathartics; Colonoscopy; Corneal Stroma; Corneal Topography; Follow-Up Studies; Humans; Lasers; Middle Aged; Myopia; Patient Satisfaction; Polyethylene Glycols; Prospective Studies; Refraction, Ocular; Treatment Outcome; Young Adult

Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antioxidants; Ascorbic Acid; Astigmatism; Corneal Pachymetry; Corneal Topography; Double-Blind Method; Female; Humans; Lens Implantation, Intraocular; Male; Middle Aged; Phacoemulsification; Postoperative Complications; Prospective Studies; Visual Acuity; Young Adult

Corneal haze is a significant complication of photorefractive keratectomy (PRK) and laser-assisted subepithelial keratectomy (LASEK).. To evaluate the effect of ascorbic acid supplementation in addition to perioperative topical mitomycin-C for the prevention of haze after LASEK.. We performed a retrospective, non-randomized case series study of two groups of 48 consecutive patients (96 myopic eyes) who had LASEK surgery. The treatment group was given ascorbic acid (vitamin C) orally, 500 mg, twice daily from 1 week before to 2 weeks after surgery. The control group was not offered any additional treatment. Ascorbate supplementation was the only difference in the postoperative treatment protocol between the treatment and control groups. Haze was assessed on a scale from 0 to 4 at the 1 year visit.. Overall, 33.3% and 37.5% of the patients in the treatment and control groups respectively developed corneal haze. The trend of increased haze severity in the control group did not reach statistical significance.. Our results showed that systemic ascorbate supplementation does not have an additional effect on the prevention of haze after LASEK compared to the effect of topical mitomycin-C alone.

Topics: Adolescent; Adult; Antioxidants; Ascorbic Acid; Astigmatism; Cornea; Corneal Opacity; Drug Therapy, Combination; Female; Humans; Keratectomy, Subepithelial, Laser-Assisted; Male; Mitomycin; Postoperative Complications; Retrospective Studies; Young Adult