ascorbic-acid-2-sulfate has been researched along with Hyperlipidemias* in 1 studies
1 other study(ies) available for ascorbic-acid-2-sulfate and Hyperlipidemias
Article | Year |
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Effect of l-ascorbate 2-sulfate on fatty liver and hyperlipidemia induced by various treatments in rats and guinea pigs.
Effects of L-ascorbate 2-sulfate (AAS) on fatty liver and hyperlipidemia induced by various treatments were studied in rats and guinea pigs. L-Ascorbic acid (AA) (50 or 175 mg/kg), a reference compound, lowered the lipid levels in the serum and/or liver in guinea pigs, while AA had little effect in rats. On the other hand, AAS (300 mg/kg) was effective in both animals. In rats, AAS lowered cholesterol and triglycerides in the serum from ethionine-treated animals and in the liver from orotic acid-supplemented animals. In guinea pigs, this compound lowered cholesterol and triglycerides in the serum from ethionine-treated animals, lipids in the liver from cholesterol-supplemented animals, and lipids in the serum and liver from scorbutic animals. AA markedly increased the content of AA in the organs in all experiments, while AAS had a slight effect. Thus, it is suggested that AAS exerts its hypolipidemic and lipotropic effects by the specific actions of AAS. Topics: Animals; Ascorbic Acid; Cholesterol; Ethionine; Fatty Liver; Female; Guinea Pigs; Hyperlipidemias; Lipids; Male; Orotic Acid; Rats; Scurvy; Sulfuric Acids; Triglycerides | 1980 |