Page last updated: 2024-08-26

artesunic acid and Neoplasms

artesunic acid has been researched along with Neoplasms in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (6.90)29.6817
2010's12 (41.38)24.3611
2020's15 (51.72)2.80

Authors

AuthorsStudies
Fu, T; Li, Y; Peng, Y; Tan, W; Tan, Y; Wang, XQ; Xuan, W1
Chen, M; Wong, KH; Xu, F; Zhao, N; Zhong, W1
Chen, J; Du, M; Gu, L; Liu, D; Liu, S; Peng, Q; Shen, S; Tian, Y; Wang, J; Xiao, W; Zhang, J1
Chen, M; Huang, D; Kappen, M; Lin, F; Liu, S; Lu, J; Lu, L; Lu, S; Luo, X; Wang, Y; Xiong, G; You, C; Yu, S; Yu, Y1
Feng, Y; Li, N; Wang, K; Zhao, C; Zhao, L; Zhou, Y1
Dong, S; Jiang, Y; Li, X; Liu, C; Wang, J; Wang, Y; Zha, W1
Dai, QL; Jia, HJ; Rui Bai, S; Wang, XB; Xia, J; Yue He, S; Zhou, M1
Chen, Y; Guan, N; Hu, Y; Wu, J; Xiong, S; Xu, H; Ye, Q1
Chen, XL; Huang, QF; Huang, ZJ; Jun, M; Li, YH; Wang, GH; Wang, W1
AlHilli, M; Beffa, L; Belinson, JL; Brainard, J; Debernardo, R; Michener, CM; Plesa, M; Ricci, S; Trimble, CL; Waggoner, SE1
Bertzbach, LD; Conradie, AM; Hahn, F; Kaufer, BB; Marschall, M; Wild, M1
Jiang, Z; Liu, Y; Tao, L; Xu, M; Xu, T1
Fan, Z; Ge, D; Han, J; Hou, Z; Huang, D; Jiang, B; Su, G; Tu, L; Xiang, S; Yang, Y; Zhao, Q; Zhu, Q1
Chen, WJ; Lin, N; Mao, X; Zhang, YQ1
Abdelfatah, S; Efferth, T; Fischer, N; Fleischer, E; Klinger, A; Seo, EJ1
Chen, J; Fan, L; Gao, L; Huang, Y; Qian, X; Xi, J; Zhang, J1
Adah, D; Chen, X; Hu, W; Qin, L1
Chen, Q; Guo, Z; Li, L; Li, T; Tu, J; Wang, X; Wu, H; Xu, P; Zhang, L; Zhang, R1
Cheema, AK; Deeken, JF; Giaccone, G; Hartley, M; He, AR; Hwang, JJ; Liu, S; Luecht, J; Marshall, JL; Pishvaian, MJ; Smaglo, B; Spiegel, JY; Wang, H; Weiner, LM1
Huang, D; Lee, YM; Lu, L; Sun, X; Wang, J; Wang, L; Wong, YK; Wu, G; Yang, L; Zhang, J; Zhao, T; Zhong, J; Zhou, C1
Fan, X; Xia, X; Zhao, M; Zhu, P1
Ng, S; Shen, HM; Shi, Y; Tan, KS; Tan, SH; Wong, WS; Yang, ND; Zhou, J1
Gannon, S; Murphy, JE; Murray, J; Rawe, S1
Liu, XL; Wang, S; Xu, LL; Xu, N; Zhou, HS; Zhou, X1
Efferth, T; Konkimalla, VB; McCubrey, JA1
Efferth, T; Eichhorn, T; Plinkert, PK; Sauer, A; Sertel, S; Sieber, S; Weiss, J1
Efferth, T; Hoheisel, JD; Youns, M1
Berdelle, N; Efferth, T; Kaina, B; Nikolova, T; Quiros, S1
Chitambar, CR; Dunstan, H; Efferth, T; Miyachi, H; Sauerbrey, A1

Reviews

4 review(s) available for artesunic acid and Neoplasms

ArticleYear
[Current research analysis and prospects on sensitization effect of artesunate on anti-cancer radiotherapy and chemotherapy].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2019, Volume: 44, Issue:23

    Topics: Artesunate; Carboplatin; Cell Line, Tumor; Cell Proliferation; Cisplatin; Doxorubicin; Humans; Neoplasms; Radiation-Sensitizing Agents

2019
The mechanisms of action of Plasmodium infection against cancer.
    Cell communication and signaling : CCS, 2021, 07-09, Volume: 19, Issue:1

    Topics: Animals; Artesunate; Cell Proliferation; Humans; Immune Checkpoint Inhibitors; Immunotherapy; Malaria; Mice; Neoplasms; Tumor Microenvironment

2021
The Relationship between Ferroptosis and Tumors: A Novel Landscape for Therapeutic Approach.
    Current gene therapy, 2019, Volume: 19, Issue:2

    Topics: Apoptosis; Artesunate; Autophagy; Cell Death; Ferroptosis; Humans; Iron; Neoplasms; Phospholipid Hydroperoxide Glutathione Peroxidase; Reactive Oxygen Species; Sulfasalazine

2019
Traditional Chinese medicines (TCMs) for molecular targeted therapies of tumours.
    Current drug discovery technologies, 2010, Volume: 7, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Arsenic Trioxide; Arsenicals; Artemisinins; Artesunate; Berberine; Biological Products; Cantharidin; Complementary Therapies; Curcumin; Drug Delivery Systems; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Humans; Medicine, Chinese Traditional; Models, Biological; Neoplasms; Oxides

2010

Trials

1 trial(s) available for artesunic acid and Neoplasms

ArticleYear
A phase I study of intravenous artesunate in patients with advanced solid tumor malignancies.
    Cancer chemotherapy and pharmacology, 2018, Volume: 81, Issue:3

    Topics: Administration, Intravenous; Adult; Antineoplastic Agents; Area Under Curve; Artesunate; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Nausea; Neoplasms; Treatment Outcome; Vomiting

2018

Other Studies

24 other study(ies) available for artesunic acid and Neoplasms

ArticleYear
A new paradigm for artesunate anticancer function: considerably enhancing the cytotoxicity via conjugating artesunate with aptamer.
    Signal transduction and targeted therapy, 2021, 09-10, Volume: 6, Issue:1

    Topics: Antineoplastic Agents; Aptamers, Nucleotide; Artesunate; HCT116 Cells; Humans; K562 Cells; Neoplasms

2021
NIR-responsive polydopamine-based calcium carbonate hybrid nanoparticles delivering artesunate for cancer chemo-photothermal therapy.
    Acta biomaterialia, 2022, Volume: 145

    Topics: Artesunate; Calcium Carbonate; Cell Line, Tumor; Doxorubicin; Humans; Indoles; Nanoparticles; Neoplasms; Phototherapy; Photothermal Therapy; Polymers; Reactive Oxygen Species

2022
Development of artesunate intelligent prodrug liposomes based on mitochondrial targeting strategy.
    Journal of nanobiotechnology, 2022, Aug-13, Volume: 20, Issue:1

    Topics: Animals; Artemisinins; Artesunate; Female; Humans; Liposomes; Mice; Mitochondria; Neoplasms; Prodrugs

2022
Near-Infrared-II Light Induced Mild Hyperthermia Activate Cisplatin-Artemisinin Nanoparticle for Enhanced Chemo/Chemodynamic Therapy and Immunotherapy.
    Small methods, 2022, Volume: 6, Issue:9

    Topics: Animals; Artemisinins; Artesunate; Cisplatin; Humans; Hyperthermia, Induced; Immunotherapy; Mice; Nanoparticles; Neoplasms; Prodrugs; Serum Albumin, Human; Tumor Microenvironment

2022
Artesunate ameliorates osteoarthritis cartilage damage by updating MTA1 expression and promoting the transcriptional activation of LXA4 to suppress the JAK2/STAT3 signaling pathway.
    Human molecular genetics, 2023, 04-06, Volume: 32, Issue:8

    Topics: Aggrecans; Animals; Artesunate; Cartilage; Chondrocytes; Collagen; Interleukin-1beta; Mice; Neoplasms; Osteoarthritis; Signal Transduction; Transcriptional Activation

2023
Local delivery of artesunate dimer liposomes incorporated injectable hydrogel for H
    International journal of pharmaceutics, 2023, Apr-05, Volume: 636

    Topics: Alginates; Animals; Artesunate; Cell Line, Tumor; Glutathione; Hemin; Hydrogels; Hydrogen Peroxide; Hydrogen-Ion Concentration; Liposomes; Mice; Nanoparticles; Neoplasms; Tumor Microenvironment

2023
Artesunate ameliorates irinotecan-induced intestinal injury by suppressing cellular senescence and significantly enhances anti-tumor activity.
    International immunopharmacology, 2023, Volume: 119

    Topics: Animals; Artesunate; Camptothecin; Cellular Senescence; Humans; Intestinal Diseases; Irinotecan; Mice; Neoplasms; TOR Serine-Threonine Kinases

2023
Flagella of Tumor-Targeting Bacteria Trigger Local Hemorrhage to Reprogram Tumor-Associated Macrophages for Improved Antitumor Therapy.
    Advanced materials (Deerfield Beach, Fla.), 2023, Volume: 35, Issue:38

    Topics: Artesunate; Bacteria; Flagella; Hemorrhage; Humans; Neoplasms; Tumor Microenvironment; Tumor-Associated Macrophages

2023
Artesunate carriers induced ferroptosis to overcome biological barriers for anti-cancer.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2023, Volume: 190

    Topics: Artesunate; Biological Availability; Ferroptosis; Humans; Hyaluronic Acid; Lipid Peroxides; Neoplasms; Reactive Oxygen Species

2023
Safety and efficacy of topical artesunate for the treatment of vulvar intraepithelial neoplasia 2/3.
    Gynecologic oncology, 2023, Volume: 178

    Topics: Artesunate; Biopsy; Carcinoma in Situ; Female; Humans; Neoplasms; Papillomavirus Infections; Prospective Studies; Vulvar Neoplasms

2023
Artesunate derivative TF27 inhibits replication and pathogenesis of an oncogenic avian alphaherpesvirus.
    Antiviral research, 2019, Volume: 171

    Topics: Alphaherpesvirinae; Animals; Antiviral Agents; Artesunate; Cell Transformation, Viral; Herpesviridae Infections; Incidence; Neoplasms; Poultry Diseases; Virus Replication

2019
Induction of APOBEC3C Facilitates the Genotoxic Stress-Mediated Cytotoxicity of Artesunate.
    Chemical research in toxicology, 2019, 12-16, Volume: 32, Issue:12

    Topics: Animals; Antineoplastic Agents; Artesunate; Cell Line, Tumor; Cell Proliferation; Cytidine Deaminase; DNA; DNA Damage; Female; G1 Phase Cell Cycle Checkpoints; G2 Phase Cell Cycle Checkpoints; Heterografts; Histones; Humans; Mice, Inbred BALB C; Neoplasms; Up-Regulation

2019
Tumor-Specific Endogenous Fe
    ACS applied materials & interfaces, 2020, Apr-01, Volume: 12, Issue:13

    Topics: Animals; Antineoplastic Agents; Artesunate; Cell Line, Tumor; Cell Survival; Drug Carriers; Ferrous Compounds; Gadolinium; Humans; Hydrogen-Ion Concentration; Magnetic Resonance Imaging; Methotrexate; Mice; Mice, Nude; Nanoparticles; Neoplasms; Rats; Reactive Oxygen Species; Theranostic Nanomedicine; Xenograft Model Antitumor Assays

2020
A novel ligand of the translationally controlled tumor protein (TCTP) identified by virtual drug screening for cancer differentiation therapy.
    Investigational new drugs, 2021, Volume: 39, Issue:4

    Topics: Antineoplastic Agents; Artesunate; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Computer Simulation; Databases, Pharmaceutical; Dose-Response Relationship, Drug; Drugs, Investigational; Humans; Ligands; Molecular Docking Simulation; Neoplasms; Tumor Protein, Translationally-Controlled 1

2021
Artesunate-loaded poly (lactic-co-glycolic acid)/polydopamine-manganese oxides nanoparticles as an oxidase mimic for tumor chemo-catalytic therapy.
    International journal of biological macromolecules, 2021, Jun-30, Volume: 181

    Topics: Animals; Artesunate; Catalysis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Humans; Indoles; Magnetic Resonance Imaging; Manganese Compounds; Mice, Inbred BALB C; Nanoparticles; Neoplasms; Oxides; Oxidoreductases; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers

2021
Bioinspired Microenvironment Responsive Nanoprodrug as an Efficient Hydrophobic Drug Self-Delivery System for Cancer Therapy.
    ACS applied materials & interfaces, 2021, Jul-28, Volume: 13, Issue:29

    Topics: Animals; Antineoplastic Agents; Artesunate; Cell Line, Tumor; Drug Carriers; Hemolysis; Histidine; Humans; Mice, Inbred BALB C; Nanoparticles; Neoplasms; Prodrugs; Proof of Concept Study

2021
Artesunate-induced mitophagy alters cellular redox status.
    Redox biology, 2018, Volume: 19

    Topics: Antimalarials; Antineoplastic Agents; Apoptosis; Artesunate; Drug Repositioning; HeLa Cells; Humans; Mitochondria; Mitophagy; Neoplasms; Oxidation-Reduction

2018
Artesunate induces cell death in human cancer cells via enhancing lysosomal function and lysosomal degradation of ferritin.
    The Journal of biological chemistry, 2014, Nov-28, Volume: 289, Issue:48

    Topics: Antimalarials; Artemisinins; Artesunate; Cell Death; Ferritins; HeLa Cells; Hep G2 Cells; Humans; Iron; Lysosomes; Neoplasm Proteins; Neoplasms; Nuclear Receptor Coactivators; Proteolysis; Vacuolar Proton-Translocating ATPases

2014
In vitro oxygen availability modulates the effect of artesunate on HeLa cells.
    Anticancer research, 2014, Volume: 34, Issue:12

    Topics: Antineoplastic Agents; Artemisinins; Artesunate; Cell Adhesion; Cell Count; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Electric Impedance; HeLa Cells; Humans; Neoplasms; Oxygen

2014
Artesunate Induces SKM-1 Cells Apoptosis by Inhibiting Hyperactive β-catenin Signaling Pathway.
    International journal of medical sciences, 2015, Volume: 12, Issue:6

    Topics: Antigens, CD; Antineoplastic Agents; Apoptosis; Artemisinins; Artesunate; beta Catenin; Cadherins; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Neoplasms; Signal Transduction

2015
The role of downstream signaling pathways of the epidermal growth factor receptor for Artesunate's activity in cancer cells.
    Current cancer drug targets, 2009, Volume: 9, Issue:1

    Topics: Artemisinins; Artesunate; Cell Line; ErbB Receptors; Humans; Neoplasms; Signal Transduction

2009
Factors determining sensitivity or resistance of tumor cell lines towards artesunate.
    Chemico-biological interactions, 2010, Apr-15, Volume: 185, Issue:1

    Topics: Antimalarials; Antineoplastic Agents, Phytogenic; Artemisinins; Artesunate; Cell Line, Tumor; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Neoplasms

2010
Artesunate induces oxidative DNA damage, sustained DNA double-strand breaks, and the ATM/ATR damage response in cancer cells.
    Molecular cancer therapeutics, 2011, Volume: 10, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Artemisinins; Artesunate; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; DNA Breaks, Double-Stranded; DNA Damage; DNA Repair; DNA-Binding Proteins; Drug Evaluation, Preclinical; Humans; Models, Biological; Neoplasms; Oxidative Stress; Protein Serine-Threonine Kinases; Tumor Cells, Cultured; Tumor Suppressor Proteins; Up-Regulation

2011
The anti-malarial artesunate is also active against cancer.
    International journal of oncology, 2001, Volume: 18, Issue:4

    Topics: Antimalarials; Antineoplastic Agents; Artemisinins; Artesunate; Cell Cycle Proteins; Cell Division; Cyclin G; Cyclin G1; Cyclins; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Fluorescent Dyes; Humans; Leukemia; Neoplasms; Poly-ADP-Ribose Binding Proteins; Proteins; Rhodamines; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sesquiterpenes; Tripeptidyl-Peptidase 1; Tumor Cells, Cultured

2001