Page last updated: 2024-08-26

artesunic acid and Lung Neoplasms

artesunic acid has been researched along with Lung Neoplasms in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (9.09)29.6817
2010's12 (54.55)24.3611
2020's8 (36.36)2.80

Authors

AuthorsStudies
Huang, C; Li, Y; Lu, H; Tang, J; Tang, Y; Wang, Y; Xiao, X; Yang, J; Zhang, Y; Zhong, Z1
Hu, P; Ni, C; Teng, P1
Huang, J; Ning, N; Zhang, W1
Cao, D; Chen, D; Chen, LW; Li, H; Li, YW; Tan, B; Wang, WY; Xia, JN; Zhang, C; Zhu, GY1
Chen, J; Fan, Y; He, T; Li, W; Liu, Y; Wang, Q; Wang, Y; Wang, Z1
Deng, Y; Li, W; Ma, G; Wang, Z; Wu, Q; Zhou, Q1
Liu, J; Liu, L; Zhao, Y1
Chen, Y; Han, H; Hu, X; Li, Q; Liu, Y; Xiong, B1
Chen, H; Dai, H; Gu, S; Li, X; Sun, D; Zhang, Z1
Rassias, DJ; Weathers, PJ1
Chen, F; Chen, X; Han, K; Huang, W; Wu, C1
Ren, T; Wang, F; Wang, X; Yang, Y; Yu, B; Zhang, X; Zhao, X1
Hu, M; Li, F; Liu, W; Liu, Y; Liu, Z; Lu, L; Ou, R; Tong, Y; Wu, J; Zhang, G; Zheng, H; Zheng, L1
Huang, J; Li, X; Lin, M; Luan, Z; Qian, H; Sha, M; Ye, L; Yuan, D; Zhang, L1
Allgayer, H; Asangani, IA; Efferth, T; Rasheed, SA1
Efferth, T; Eichhorn, T; Johnson, SW; Plinkert, PK; Sertel, S; Simon, CH1
Dalgleish, AG; Gravett, AM; Liu, WM1
Cen, Y; Dong, J; Jiang, W; Li, B; Li, J; Pan, X; Pang, X; Yao, Q; Zhao, Y; Zheng, J; Zhou, H1
Chen, ZT; Lin, S; Ma, H; Sun, JG; Wang, XX; Wu, L; Yao, Q; Zhang, AM1
Chen, TS; Pan, W; Wang, XP; Zhou, C1
Baur, A; Berger, TG; Dieckmann, D; Efferth, T; Funk, JO; Schuler, G; Schultz, ES1
Huang, XY; Li, DQ; Miao, LY; Xia, XH; Yu, SQ; Zhang, XP; Zhang, ZY; Zhu, YP1

Trials

1 trial(s) available for artesunic acid and Lung Neoplasms

ArticleYear
[Artesunate combined with vinorelbine plus cisplatin in treatment of advanced non-small cell lung cancer: a randomized controlled trial].
    Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, 2008, Volume: 6, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Artemisinins; Artesunate; Carcinoma, Non-Small-Cell Lung; Cisplatin; Drug Administration Schedule; Female; Humans; Lung Neoplasms; Male; Middle Aged; Vinblastine; Vinorelbine

2008

Other Studies

21 other study(ies) available for artesunic acid and Lung Neoplasms

ArticleYear
Dihydroartemisinin and artesunate inhibit aerobic glycolysis via suppressing c-Myc signaling in non-small cell lung cancer.
    Biochemical pharmacology, 2022, Volume: 198

    Topics: Animals; Artemisinins; Artesunate; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Glucose; Glycolysis; Lung Neoplasms; Mice; Proto-Oncogene Proteins c-myc; Signal Transduction

2022
Effects of artesunate on the malignant biological behaviors of non-small cell lung cancer in human and its mechanism.
    Bioengineered, 2022, Volume: 13, Issue:3

    Topics: A549 Cells; Apoptosis; Artesunate; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dimethyl Sulfoxide; Humans; Lung Neoplasms; Matrix Metalloproteinase 9; Signal Transduction

2022
Artesunate Suppresses the Growth of Lung Cancer Cells by Downregulating the AKT/Survivin Signaling Pathway.
    BioMed research international, 2022, Volume: 2022

    Topics: A549 Cells; Animals; Apoptosis; Artesunate; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Humans; Lung Neoplasms; Mice; Mice, Nude; Proto-Oncogene Proteins c-akt; Signal Transduction; Survivin

2022
Artesunate promoted anti-tumor immunity and overcame EGFR-TKI resistance in non-small-cell lung cancer by enhancing oncogenic TAZ degradation.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 155

    Topics: Animals; Artesunate; B7-H1 Antigen; Carcinoma, Non-Small-Cell Lung; Drug Resistance, Neoplasm; ErbB Receptors; Gefitinib; Humans; Immune Checkpoint Inhibitors; Lung Neoplasms; Mice; Molecular Docking Simulation; Mutation; Proteasome Endopeptidase Complex; Protein Kinase Inhibitors; Transcription Factors

2022
The combination of artesunate and carboplatin exerts a synergistic anti-tumour effect on non-small cell lung cancer.
    Clinical and experimental pharmacology & physiology, 2020, Volume: 47, Issue:6

    Topics: A549 Cells; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Artesunate; Carboplatin; Carcinoma, Non-Small-Cell Lung; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Drug Synergism; G2 Phase Cell Cycle Checkpoints; Gemcitabine; Humans; Lung Neoplasms; Mitochondria; Signal Transduction

2020
Artesunate exhibits synergistic anti-cancer effects with cisplatin on lung cancer A549 cells by inhibiting MAPK pathway.
    Gene, 2021, Jan-15, Volume: 766

    Topics: A549 Cells; Animals; Antineoplastic Agents; Apoptosis; Artesunate; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cisplatin; Drug Synergism; Female; Humans; Lung Neoplasms; MAP Kinase Signaling System; Mice; Mice, Nude; Protein Kinase Inhibitors; Signal Transduction

2021
Artesunate inhibits lung cancer cells via regulation of mitochondrial membrane potential and induction of apoptosis.
    Molecular medicine reports, 2020, Volume: 22, Issue:4

    Topics: A549 Cells; Antineoplastic Agents; Artesunate; bcl-2-Associated X Protein; Cell Proliferation; Cell Survival; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Membrane Potential, Mitochondrial; Mitochondria; Proto-Oncogene Proteins c-bcl-2

2020
Artesunate-loaded porous PLGA microsphere as a pulmonary delivery system for the treatment of non-small cell lung cancer.
    Colloids and surfaces. B, Biointerfaces, 2021, Volume: 206

    Topics: Artesunate; Carcinoma, Non-Small-Cell Lung; Humans; Lactic Acid; Lung Neoplasms; Microspheres; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity

2021
The selectivity of artemisinin-based drugs on human lung normal and cancer cells.
    Environmental toxicology and pharmacology, 2018, Volume: 57

    Topics: A549 Cells; Artemisinins; Artesunate; Bronchi; Cell Line; Cell Survival; Comet Assay; DNA Damage; Epithelial Cells; Humans; Lung Neoplasms; Reactive Oxygen Species

2018
Dried leaf Artemisia annua efficacy against non-small cell lung cancer.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2019, Volume: 52

    Topics: A549 Cells; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Artemisia annua; Artemisinins; Artesunate; Carcinoma, Non-Small-Cell Lung; Caspases; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; DNA Breaks, Double-Stranded; Female; Humans; Lung Neoplasms; Mice; Mice, Nude; Plant Leaves; Signal Transduction; Xenograft Model Antitumor Assays

2019
[Effects of artesunate on the invasion of lung adenocarcinoma A549 cells and expression of ICAM-1 and MMP-9].
    Zhongguo fei ai za zhi = Chinese journal of lung cancer, 2013, Volume: 16, Issue:11

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Artemisinins; Artesunate; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Humans; Intercellular Adhesion Molecule-1; Lung Neoplasms; Matrix Metalloproteinase 9; Mice; Mice, Nude

2013
Enhanced delivery of artemisinin and its analogues to cancer cells by their adducts with human serum transferrin.
    International journal of pharmaceutics, 2014, Jun-05, Volume: 467, Issue:1-2

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Artemisinins; Artesunate; Carcinoma, Hepatocellular; Cell Proliferation; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Carriers; Drug Stability; Hep G2 Cells; Humans; Lactones; Liver Neoplasms; Lung Neoplasms; Molecular Docking Simulation; Molecular Structure; Nanotechnology; Protein Conformation; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Technology, Pharmaceutical; Transferrin

2014
Artemisinin and its derivatives can significantly inhibit lung tumorigenesis and tumor metastasis through Wnt/β-catenin signaling.
    Oncotarget, 2016, May-24, Volume: 7, Issue:21

    Topics: A549 Cells; Animals; Antimalarials; Artemisinins; Artesunate; beta Catenin; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Female; Humans; Lung Neoplasms; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; RNA Interference; Wnt Signaling Pathway; Xenograft Model Antitumor Assays

2016
Downregulation of HOTAIR Expression Mediated Anti-Metastatic Effect of Artesunate on Cervical Cancer by Inhibiting COX-2 Expression.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Animals; Antineoplastic Agents; Artemisinins; Artesunate; Cell Line, Tumor; Cell Movement; Cyclooxygenase 2; Dinoprostone; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Immunoprecipitation; Lung Neoplasms; Mice; Mice, Nude; Protein Binding; RNA Interference; RNA, Long Noncoding; RNA, Small Interfering; Transplantation, Heterologous; Uterine Cervical Neoplasms

2016
First evidence that the antimalarial drug artesunate inhibits invasion and in vivo metastasis in lung cancer by targeting essential extracellular proteases.
    International journal of cancer, 2010, Sep-01, Volume: 127, Issue:6

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Chick Embryo; Enzyme-Linked Immunosorbent Assay; Gene Expression Profiling; Humans; Lung Neoplasms; Matrix Metalloproteinases; Neoplasm Invasiveness; Neoplasm Metastasis; Polymerase Chain Reaction; RNA, Messenger; Urokinase-Type Plasminogen Activator

2010
Pharmacogenomic identification of c-Myc/Max-regulated genes associated with cytotoxicity of artesunate towards human colon, ovarian and lung cancer cell lines.
    Molecules (Basel, Switzerland), 2010, Apr-22, Volume: 15, Issue:4

    Topics: Artemisinins; Artesunate; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Cell Line, Tumor; Colonic Neoplasms; Drug Resistance, Neoplasm; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genes, Neoplasm; Humans; Inhibitory Concentration 50; Lung Neoplasms; Oligonucleotide Array Sequence Analysis; Ovarian Neoplasms; Pharmacogenetics; Proto-Oncogene Proteins c-myc

2010
The antimalarial agent artesunate possesses anticancer properties that can be enhanced by combination strategies.
    International journal of cancer, 2011, Mar-15, Volume: 128, Issue:6

    Topics: Antimalarials; Antineoplastic Combined Chemotherapy Protocols; Artemisinins; Artesunate; Blotting, Western; Breast Neoplasms; Cell Proliferation; Colonic Neoplasms; Deoxycytidine; Female; Flow Cytometry; Gemcitabine; Humans; Lenalidomide; Lung Neoplasms; Organoplatinum Compounds; Oxaliplatin; Thalidomide; Tumor Cells, Cultured

2011
Artesunate enhances radiosensitivity of human non-small cell lung cancer A549 cells via increasing NO production to induce cell cycle arrest at G2/M phase.
    International immunopharmacology, 2011, Volume: 11, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Artemisinins; Artesunate; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cell Line, Tumor; Combined Modality Therapy; Cyclin B1; Down-Regulation; Humans; Lung Neoplasms; Nitric Oxide; Radiation-Sensitizing Agents

2011
The effects of artesunate on the expression of EGFR and ABCG2 in A549 human lung cancer cells and a xenograft model.
    Molecules (Basel, Switzerland), 2011, Dec-19, Volume: 16, Issue:12

    Topics: Animals; Artemisinins; Artesunate; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Carcinoma, Non-Small-Cell Lung; Cell Death; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Down-Regulation; ErbB Receptors; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Neoplasm Proteins; Phosphorylation; Proto-Oncogene Proteins c-akt; RNA, Messenger; Xenograft Model Antitumor Assays

2011
Artesunate induces apoptosis via a Bak-mediated caspase-independent intrinsic pathway in human lung adenocarcinoma cells.
    Journal of cellular physiology, 2012, Volume: 227, Issue:12

    Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Artemisinins; Artesunate; bcl-2 Homologous Antagonist-Killer Protein; Bcl-2-Like Protein 11; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Membrane Proteins; Proto-Oncogene Proteins; Reactive Oxygen Species; Voltage-Dependent Anion Channel 2

2012
Artesunate in the treatment of metastatic uveal melanoma--first experiences.
    Oncology reports, 2005, Volume: 14, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Artemisia; Artemisinins; Artesunate; Dacarbazine; Fatal Outcome; Female; Humans; Liver Neoplasms; Lung Neoplasms; Male; Melanoma; Sesquiterpenes; Time Factors; Treatment Outcome; Uveal Neoplasms

2005