artesunic acid has been researched along with Infections, Plasmodium in 377 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 13 (3.45) | 18.7374 |
1990's | 15 (3.98) | 18.2507 |
2000's | 92 (24.40) | 29.6817 |
2010's | 165 (43.77) | 24.3611 |
2020's | 92 (24.40) | 2.80 |
Authors | Studies |
---|---|
Anstey, NM; Barber, BE; Cooper, DJ; Grigg, MJ; Rajahram, GS; van Schalkwyk, DA; William, T | 1 |
Boechat, N; Campos Aguiar, AC; da Silva Araújo, M; Krettli, AU; Medeiros, JF; Penna-Coutinho, J; Pereira, DB; Rios, CT; Sá, PM | 1 |
Barton, M; Brooks, HM; Forgie, EME; Hawkes, MT | 1 |
Achia, TN; Amboko, B; Chesang, J; Kipruto, H; Machini, B; Mwaniki, P | 1 |
Abohelwa, M; Agusala, V; Gharamti, A; Hassan, M | 1 |
Amboko, B; Bejon, P; Githuka, G; Machini, B; Snow, RW; Zurovac, D | 1 |
Guo, Q; Lin, L; Shi, Z; Tang, Z; Xiong, H | 1 |
Bartoloni, A; Bianchi, L; Botta, A; Castelli, F; Chechi, F; Comelli, A; Galli, L; Giulia, G; Spinicci, M; Tomasoni, LR; Vellere, I; Zammarchi, L | 1 |
Baraka, V; Kamugisha, E; Kapesa, A; Kidenya, B; Konje, E; Marwa, K; Mukonzo, J; Swedberg, G | 1 |
Bottieau, E; Huits, R; Rosanas-Urgell, A; Van den Bossche, D; Van Ierssel, S | 1 |
Creek, DJ; Dogovski, C; Du, Y; Giannangelo, C; He, W; Li, X; Shami, GJ; Tilley, L; Yang, T; Zhou, W | 1 |
Behera, PK; Nair, AA; Tripathy, KP | 1 |
Asinya, M; Jeuronlon, MK; Kamara, P; Koko, VS; Kollie, A; Ma, L; Menard, D; Nyansaiye, P; Parwon, S; Pratt, OJ; Ringwald, P; Taweh, F; Tehmeh, L; Vonhm, B; Warsame, M | 1 |
Oraebosi, MI | 1 |
Basco, LK; Briolant, S; Casimiro, PN; Kobawila, SC; Matondo Diassivi, B; Ndounga, M; Pembet Singana, B; Ringwald, P; Youndouka, JM | 1 |
Grundmann, O; Hernandez Maldonado, J | 1 |
Akano, B; Angiro, I; Athieno, P; Awor, P; Ayodeji, K; Brunner, NC; Buj, V; Burri, C; Cereghetti, N; Delvento, G; Hetzel, MW; Kalenga, JC; Kimera, J; Lambiris, MJ; Lee, TT; Lengeler, C; Napier, HG; Okitawutshu, J; Okon, C; Omoluabi, E; Ross, A; Signorell, A; Tshefu Kitoto, A; Tumukunde, G; Visser, T; Yusuf, O | 1 |
Arbe-Barnes, S; Borghini-Fuhrer, I; Dimessa Mbadinga, LB; Duparc, S; Egger-Adam, D; Groger, M; Kahunu Mesia, G; Miller, R; Mombo-Ngoma, G; Muena Mujobu, TB; Ntamabyaliro, NY; Ramharter, M; Shin, J; Tona Lutete, G; Zoleko Manego, R | 1 |
Bivona, DA; Bonacci, P; Marino, A | 1 |
Jochum, J; Kurth, F; Mischlinger, J; Ramharter, M | 1 |
Bruschi, F; Fabiani, S; L'Episcopia, M; Mangano, V; Motta, V; Severini, C; Sparavelli, R; Verdenelli, S | 1 |
Baguiya, A; Barry, N; Hien, D; Kaboré, JMT; Siribié, M; Sirima, SB; Soulama, I; Tchouatieu, AM; Tiono, AB | 1 |
Dondorp, AM; Fanello, C; Onyamboko, M; Peto, TJ; Warsame, M; Watson, JA; White, N | 1 |
Baiden, R; Binka, F; Compaore, A; Diande, NA; Hien, FS; Rouamba, T; Sondo, P; Tahita, MC; Tinto, H; Traore-Coulibaly, M; Valea, I; Yerbanga, IW | 1 |
Daily, JP; Khan, N; Minuti, A | 1 |
Bamadio, A; Chico, RM; Cohee, LM; Coumare, S; Dara, A; Diarra, M; Djimde, AA; Doumbo, OK; Kodio, A; Maiga, H; Opondo, C; Sagara, I; Sidibe, B; Tekete, M; Traore, OB; Traore, ZI | 1 |
Lucchi, NW; Mace, KE; Tan, KR | 1 |
Abanyie, F; Ng, J; Tan, KR | 1 |
Choi, G; Choy, JH; Kim, JY; Lee, SE; Piao, H; Rejinold, NS; Shin, HI | 1 |
Alpern, JD; Stauffer, WM; Thomas, CM | 1 |
Rathjen, NA; Shahbodaghi, SD | 1 |
Brunner, N; Buj, V; Burri, C; Delvento, G; Hetzel, M; Kalenga, JC; Lee, T; Lengeler, C; Luketa, S; Mukomena, E; Mwaluke, F; Okitawutshu, J; Sangare, M; Signorell, A; Tshefu, A | 1 |
White, NJ | 2 |
Akano, BK; Angiro, I; Athieno, P; Awor, P; Ayodeji, K; Brunner, NC; Buj, V; Burri, C; Cereghetti, N; Cohen, JM; Delvento, G; Hetzel, MW; Kalenga, JC; Kimera, J; Kwiatkowski, M; Lambiris, MJ; Lee, TT; Lengeler, C; Napier, HG; Okitawutshu, J; Okon, C; Omoluabi, E; Signorell, A; Tshefu, A; Tumukunde, G; Visser, T; Yusuf, O | 1 |
Adebayo, JO; Tijjani, H | 1 |
Adegnika, AA; Akinosho, MA; Davi, SD; Dimessa-Mbadinga, LB; Handrich, C; Kreidenweiss, A; Kremsner, PG; Lell, B; Mombo-Ngoma, G; Ndzebe-Ndoumba, WF; Nordmann, T; Okwu, DG; Ramharter, M; Stelzl, D; Veletzky, L; Zoleko-Manego, R | 1 |
Akano, B; Athieno, P; Awor, P; Ayodeji, K; Brunner, N; Burri, C; Delvento, G; Hetzel, MW; Kalenga, JC; Kimera, J; Lee, T; Lengeler, C; Okitawutshu, J; Okon, C; Omoluabi, E; Signorell, A; Tshefu, A; Tumukunde, G; Yusuf, O | 1 |
Awor, P; Buj, V; Burri, C; Cohen, JM; Hetzel, MW; Lambiris, MJ; Lengeler, C; Omoluabi, E; Signorell, A; Tshefu, A; Visser, T | 1 |
von Seidlein, L | 1 |
Accrombessi, M; Cook, J | 1 |
Awor, P; Balogun, V; Brunner, NC; Buj, V; Burri, C; Cereghetti, N; Delvento, G; Emedo, E; Galactionova, K; Hetzel, MW; Kagwire, F; Lambiris, MJ; Lee, TT; Lengeler, C; Luketa, S; Musiitwa, M; Napier, HG; Okitawutshu, J; Olosunde, O; Omoluabi, E; Sangare, M; Signorell, A; Ssempala, R; Tshefu, A; Venga, GN; Visser, T | 1 |
Dondorp, AM; Peto, TJ; Watson, JA; White, NJ | 1 |
Mace, KE; Schultz, JS; Tan, KR | 1 |
Chandelia, S; Gangwal, M; Patharia, N | 1 |
Akano, BK; Angiro, I; Athieno, P; Awor, P; Ayodeji, K; Brunner, NC; Buj, V; Burri, C; Cereghetti, N; Delvento, G; Hetzel, MW; Kalenga, JC; Kimera, J; Lambiris, MJ; Lee, TT; Lengeler, C; Napier, HG; Okitawutshu, J; Okon, C; Okuma, J; Omoluabi, E; Signorell, A; Tshefu, A; Tumukunde, G; Visser, T; Yusuf, O | 1 |
Moffitt, CA; O'Brien, N; Olupot-Olupot, P; Onen, JW | 1 |
Babigumira, K; Lugand, MM; Muniina, P; Nsona, H; Oliff, MS; Phuka, J; Rietveld, H; Sande, J | 1 |
Liu, Z; Ma, Z; Sun, CB | 1 |
Awor, P; Buj, V; Burri, C; Cohen, JM; Hetzel, MW; Kwiatkowski, M; Lambiris, MJ; Lengeler, C; Okitawutshu, J; Omoluabi, E; Signorell, A; Tshefu, A; Visser, T | 1 |
Peto, TJ; Watson, JA; White, NJ | 2 |
Bertault-Peres, P; Bonsergent, M; Flet, L; Honoré, S; Lepelletier, A; Perez, T; Tching-Sin, M | 1 |
Barber, C; Chanda, E; Green, C; Kureya, T; Moyo, B; Mpande, B; Mubuyaeta, K; Mudenda, M; Mundia, L; Nyirenda, R; Piringondo, A; Quigley, P; Rietveld, H; Simpasa, S; Simuyuni, D; Zinumwe, G | 1 |
Alexander, K; Anstey, NM; Buffet, PA; Candrawati, F; Kambuaya, NN; Kenangalem, E; Kho, S; Leonardo, L; Margayani, DS; Poespoprodjo, JR; Prayoga, P; Rini, H; Shanti, PAI; Yayang, BTG | 1 |
Hasan, N; Hore, R; Kressler, J; Mäder, K | 1 |
Li, Y; Qiu, M; Rong, R; Su, J; Xu, E; Yuan, W; Zhang, S | 1 |
Baraka, V; Francis, F; Geertruyden, JV; Gesase, S; Kyaruzi, E; Lusingu, JPA; Madebe, R; Makenga, G; Minja, DTR; Mtove, G; Nakato, S | 1 |
Dini, S; Fanello, C; Fitzpatrick, P; Haghiri, A; Price, DJ; Rajasekhar, M; Simpson, JA; Tarning, J; Watson, J; White, NJ | 1 |
Chellan, P; Harding, CR; Kaschula, CH; Munnik, BL | 1 |
Angeli, A; Capasso, C; Carradori, S; Carta, F; D'Agostino, I; De Luca, V; Kocken, CHM; Supuran, CT; Zara, S; Zeeman, AM | 1 |
Arama, C; Beavogui, AH; Dicko, A; Djimde, A; Djimde, M; Fofana, B; Kayentao, K; Mens, PF; Ouedraogo, JB; Sagara, I; Schallig, HD; Sirima, SB; Tshiongo, JK | 1 |
Burri, C; Delvento, G; Hetzel, MW; Kalenga, JC; Lengeler, C; Okitawutshu, J; Signorell, A; Tshefu, A | 1 |
Campagnucci, N; Chediack, V; Cunto, E; Gregori Sabelli, R; Lamberto, Y; Saul, P | 1 |
Angoulvant, A; Bouchaud, O; Buffet, P; Caumes, E; Chamillard, X; Houzé, S; Izri, A; Jauréguiberry, S; Kendjo, E; Magne, D; Matheron, S; Ndour, AP; Paccoud, O; Surgers, L; Thellier, M; Vinatier, I; Wyplosz, B | 1 |
Bienvenu, AL; Bonnot, G; Kouakou, YI; Lavoignat, A; Leboucher, G; Picot, S; Tod, M | 1 |
Lefèvre, A; Léonard, P | 1 |
Addo, MM; Adegnika, AA; Agbenyega, T; Ansong, D; Cramer, JP; Fürst, S; Jacobs, T; Kremsner, PG; Kurth, F; May, J; Ramharter, M; Rolling, T; Scheu, K; Sylverken, J; Vinnemeier, CD | 1 |
Barber, C; Chanda, E; Chizema, E; Green, C; Hugo, P; Kureya, T; Moonga, H; Mpande, B; Mubuyaeta, K; Quigley, P; Simfukwe, V; Simuyuni, D; van der Weije, K | 1 |
Conroy, AL; Elphinstone, RE; Hawkes, MT; Hume, HA; Kain, KC; Namasopo, S; Opoka, RO | 1 |
Faye, O; Musau, J; Mvumbi, PM; Okitolonda, E; Situakibanza, H | 1 |
Ahmad, RA; Kenangalem, E; Laksono, IS; Lampah, DA; Murhandarwati, EEH; Poespoprodjo, JR; Sikora, SA; Sugiarto, P | 1 |
Anvikar, AR; Das, MK; Mitra, JK; Savargaonkar, D; Srivastava, B; Valecha, N; Verma, A; Yadav, CP | 1 |
Petersen, E; Picot, S | 1 |
Ariey, F; Chy, S; Dorina Bustos, M; Eam, R; Izac, B; Kauy, C; Ke, S; Khim, N; Kim, S; Kloeung, N; Leang, R; Mairet-Khedim, M; Marmai, C; Mey Bouth, D; Ringwald, P; Witkowski, B | 1 |
Acácio, S; Aide, P; Alonso, PL; Bambo, G; Bassat, Q; Camprubí, D; Macete, E; Madrid, L; Mayor, A; Menéndez, C; Muñoz, J; Quintó, L; Sitoe, A; Valente, AM; Varo, R; Vitorino, P | 1 |
Essiben, F; Mayane, DN; Meka, E; Nkwabong, E | 1 |
Bianchi, L; Bortone, B; Chiappini, E; Galli, L; Montagnani, C; Tersigni, C; Venturini, E; Zammarchi, L | 1 |
Abbas, FB; Ali, AS; Ali, AW; Barnes, R; Björkman, A; Frumento, P; Mårtensson, A; Morris, U; Msellem, M; Soe, A | 1 |
Achia, TNO; Amboko, B; Kipruto, H; Machini, B; Malla, L; Snow, RW; Zurovac, D | 1 |
Chandramohan, D; Clark, TD; Dorsey, G; Havlir, DV; Jagannathan, P; Kajubi, R; Kakuru, A; Kamya, MR; Nakalembe, M; Ochieng, T; Ochokoru, H; Ruel, T; Staedke, SG | 1 |
Aschenbrenner, DS | 1 |
Baker, L; Barnes, KI; Blaylock, M; Blumberg, L; Frean, J; Misiani, E; Raman, J; Ukpe, IS | 1 |
Al Khaja, KAJ; Sequeira, RP | 1 |
Angoulvant, A; Argy, N; Bouchaud, O; Bruneel, F; Buffet, P; Caumes, E; Chambrion, C; Courtin, D; Danis, M; Delacour, H; Gay, F; Henry, B; Houzé, S; Jauréguiberry, S; Kendjo, E; Larréché, S; Lebrun-Vignes, B; Mouri, O; Ndour, PA; Piarroux, R; Roussel, C; Siriez, JY; Taieb, A; Thellier, M | 1 |
Ball, L; Bensman, TJ; Chilukuri, DM; Colangelo, PM; Earp, JC; Kitabi, E; O'Shaughnessy, E; Reynolds, KS; Smith, H; Yasinskaya, Y | 1 |
Arwati, H; Basuki, DR; Ekasari, W; Wahyuni, TS | 1 |
Cao, P; Dini, S; Dondorp, A; Fowkes, FJI; Kremsner, P; Krishna, S; Maude, RJ; McCaw, JM; Price, RN; Simpson, JA; Tarning, J; White, MT; White, NJ; Whyte, JM; Zaloumis, SG | 1 |
Hughes, E; Jagannathan, P; Mohamed Ali, A; Savic, RM; Wallender, E | 1 |
Achan, J; Arbe-Barnes, S; Borghini-Fuhrer, I; Conteh, B; D'Alessandro, U; Dabira, ED; Duparc, S; Hachizovu, S; Lawal, B; Manyando, C; Mendy, A; Miller, R; Mulenga, JM; Mwanza, S; Ndiath, MO; Nyang, H; Shin, J | 1 |
Bancone, G; Carrara, VI; Chu, C; Duanguppama, J; Gilder, ME; Haohankhunnatham, W; Imwong, M; Konghahong, K; Lee, SJ; McGready, R; Min, AM; Nosten, F; Paw, MK; Phyo, AP; Pimanpanarak, M; Proux, S; Saito, M; Singhasivanon, P; Tun, NW; Turner, C; Viladpai-Nguen, J; White, NJ | 1 |
Agnandji, ST; Allen, SJ; Arbe-Barnes, S; Assi, SB; Bigoga, JD; Borghini-Fuhrer, I; Duparc, S; Groger, M; Koukouikila-Koussounda, F; Kremsner, PG; Miller, R; Mombo-Ngoma, G; Ntamabyaliro, NY; Ntoumi, F; Ramharter, M; Shin, J; Tona Lutete, G | 1 |
Adah, D; Chen, X; Hu, W; Qin, L | 1 |
Chai, L; Guo, W; Li, N; Li, Y; Ren, G; Wang, R; Wang, X; Yang, L; Yang, Q; Yi, B; Zhang, G; Zhang, S | 1 |
Abanyie, F; Acharya, SD; Bowe, M; Leavy, I; Tan, KR | 1 |
Balogun, AA; Olanlokun, JO; Olorunsogo, OO | 1 |
Asuzu, OV; Ezeigbo, II; Nwaehujor, CO; Nwibo, DD; Nwobi, OC | 1 |
Buffet, PA; Caumes, E; Jauréguiberry, S; Ndour, PA; Roussel, C; Thellier, M | 1 |
Buyze, J; D'Alessandro, U; Hachizovu, S; Kabuya, JB; Kasongo, W; Mulenga, J; Mulenga, M; Mwakazanga, D; Nambozi, M; Van Geertruyden, JP | 1 |
Chang, ZW; Claser, C; Rénia, L; Russell, B | 1 |
Argy, N; Biligui, S; Bonnefoy, S; Buffet, PA; Chartrel, N; Danis, M; Dondorp, AM; Gay, F; Ghose, A; Hassan, MMU; Hossain, MA; Houzé, S; Jauréguiberry, S; Kendjo, E; Kingston, HWF; Langui, D; Larréché, S; Mérens, A; Mouri, O; Ndour, PA; Perillaud, C; Plewes, K; Roussel, C; Thellier, M; Woodrow, CJ | 1 |
Barboza, TMT; Chaves, GC; Gonçalves, LPB; Luiza, VL; Stobbaerts, EG | 1 |
Bagire, PG; Daddy, NB; Kalisya, LM; Towler, MJ; Watt, RL; Weathers, PJ | 1 |
Akter, J; Aogo, RA; Best, SE; Cromer, D; Davenport, MP; Elliott, T; Engel, JA; Gartlan, KH; Haque, A; James, KR; Khoury, DS; Sebina, I; Soon, MSF; Thomas, BS | 1 |
Amin, P; Baker, T; Karnad, DR; Nor, MBM; Richards, GA | 1 |
Kumar, RS; Puttappa, N; Yamjala, K | 1 |
Falade, MO; Komoni, F; Nwuba, RI | 1 |
Achan, J; Byakika-Kibwika, P; Karera-Gonahasa, C; Kiragga, AN; Kiwanuka, N; Lamorde, M; Mayanja-Kizza, H; Merry, C; Nsobya, S; Talisuna, AO | 1 |
Du, Y; Ismail, M; Li, X; Ling, L; Yao, C | 1 |
Crawley, J; Dondorp, A; Keene, CM; Mukaka, M; Ohuma, EO | 1 |
Amin, P; Karnad, DR; Richards, GA; Silva, GS | 1 |
Alexander, ND; Chandramohan, D; Clarke, SE; Hansen, KS; Lal, S; Magnussen, P; Ndyomugenyi, R; Paintain, L | 1 |
Anstey, NM; Barber, BE; Chandna, A; Drakeley, CJ; Grigg, MJ; Menon, J; Patel, K; Piera, K; Rajahram, GS; Schimann, E; Wilkes, CS; William, T; Yeo, TW | 1 |
Helinski, MEH; Muhangi, D; Nuwa, A; Okui, AP; Strachan, CE; Tibenderana, JK | 1 |
Akter, J; Aogo, RA; Cromer, D; Davenport, MP; Elliott, T; Fogg, LG; Haque, A; Khoury, DS; Laohamonthonkul, P; Liligeto, UN; Nair, AS; Pernold, CPS; Romanczuk, AS; Soon, MSF; Thomas, BS | 1 |
Dias, S; Donegan, S; Welton, NJ | 1 |
Du, Y; Ismail, M; Li, X; Ling, L | 1 |
Almuedo, A; Bassat, Q; Camprubí, D; Casals-Pascual, C; Malvy, D; Muñoz, J; Pereira, A; Rodriguez-Valero, N; Varo, R | 1 |
Jauréguiberry, S | 1 |
Garrido Jareño, M; Otero Reigada, MDC; Peman García, J; Ramírez Cuentas, JH; Roselló Guijarro, M; Urtasun Erburu, A | 1 |
Alcalá-Minagorre, PJ; Rabaneda-Gutiérrez, L; Sánchez-Bautista, A | 1 |
Arbe-Barnes, S; Borghini-Fuhrer, I; Craft, CJ; Duparc, S; Fleckenstein, L; Miller, RM; Shin, CS | 1 |
Ashley, E; Boel, M; Carrara, VI; Chu, C; Lwin, KM; McGready, R; Nosten, F; Phyo, AP; Proux, S; Rijken, M; Singhasivanon, P; Sriprawat, K; White, N; Wiladphaingern, J | 1 |
Bagai, U; Rajan, A | 1 |
Efferth, T; Eichhorn, T; Schneider, D; Veerappan, A; Zeino, M | 1 |
Goto, T; Kameta, K; Kaneshima, H; Nakao, T; Shirono, N; Yamane, T; Yoshida, T | 1 |
Bunts, L; Casper, C; Dorsey, G; Gantt, S; Huang, ML; Magaret, A; Rosenthal, PJ; Selke, S; Wald, A | 1 |
Burchard, GD; Cramer, JP; Kluge, S; Rolling, T; Schmiedel, S; Wichmann, D | 1 |
Dondorp, AM; Faiz, MA; Hien, TT; Mokuolu, OA; Pukrittayakamee, S; White, NJ | 1 |
de Vries, PJ; Kreeftmeijer-Vegter, AR; van Veldhuizen, CK | 1 |
Agbaje, EO; Aina, OO; Iribhogbe, OI; Oreagba, IA; Ota, AD | 1 |
Bathurst, I; Brun, R; Burrows, JN; Charman, SA; Fantauzzi, P; Ihara, M; Itoh, I; Lotharius, J; Morizzi, J; Scheurer, C; Schleiferböck, S; Shackleford, DM; White, KL; Wittlin, S | 1 |
Clark, RL | 1 |
Adegnika, AA; Agbenyega, T; Ansong, D; Burchard, GD; Cramer, JP; Issifou, S; Kremsner, PG; Krishna, S; Löhr, SJ; May, J; Mordmüller, B; Rolling, T; Spahlinger, D; Sylverken, J | 1 |
Burchard, GD | 1 |
Adedeji, WA; Adewole, IF; Akinola, IT; Akinyinka, OO; Aweeka, FT; Darin, KM; Fehintola, FA; Lindegardh, N; Ma, Q; Morse, GD; Murphy, RL; Ojengbede, O; Parikh, S; Scarsi, KK; Taiwo, B; Tarning, J | 1 |
Attama, AA; Chime, SA; Chinaeke, EE; Okore, VC; Onyishi, VI | 1 |
Amah, DJ; Bello, UM; Gbodi, AT; Kabiru, AY; Makun, HA; Ogbadoyi, EO | 1 |
Anvikar, AR; Das, MK; Gupta, R; Mishra, N; Rana, R; Shahi, B; Singh, S; Valecha, N | 1 |
Ashley, EA; Gomes, M; Libaud-Moal, A; Millet, P; Olliaro, P; Rodrigues, A; Vermeersch, A; White, NJ | 1 |
Aguiar, AC; Amaral, NS; De Marco, L; Krettli, AU; Pereira, DB | 1 |
Kumar, KK; Prasad, DM; Rajyalakshmi, M; Satish, PV; Sowjanya, M; Sunita, K | 1 |
Kameda, K | 1 |
Huijben, S; Jones, MJ; Pollitt, LC; Read, AF; Salathé, RM; Sim, DG | 1 |
Eisenhut, M; Okebe, J | 1 |
Adegbolagun, OM; Emikpe, BO; Ogunremi, Y; Woranola, IO | 2 |
Das, MK; Savargaonkar, D; Shah, N; Srivastava, B; Valecha, N | 1 |
Chen, L; Choi, K; Gibson, C; Huang, F; Keitany, GJ; Peng, X; Vignali, M; Wang, R | 1 |
Attama, AA; Chime, SA; Chinaeke, EE; Müller-Goymann, CC; Ogbonna, JD; Okore, VC | 1 |
Anstey, NM; Barber, BE; Dhanaraj, P; Grigg, MJ; Menon, J; Price, RN; Rajahram, G; von Seidlein, L; William, T; Yeo, TW | 1 |
Boonloed, A; Dunfield, EM; Koesdjojo, MT; Remcho, VT; Wu, Y | 1 |
Green, MD; Herrington, J; Newton, PN; Phonlavong, C; Ranieri, N; Sampson, E; Satzger, RD; Tabernero, P; Thao, K; Verbois, L; Witkowski, MR | 1 |
Berman, J; Im-Erbsin, R; Li, Q; Obaldia, N; Ohrt, C; Xie, L | 1 |
Corsello, MA; Garg, NK | 1 |
Boggild, AK; Graham, C; Kain, KC; Keystone, JS; Krajden, S; Lee, J; Pavenski, K | 1 |
Jongwutiwes, S; Kobasa, T; Nakaviroj, S; Putaporntip, C; Teeranaipong, P | 1 |
Claeys, Y; D'Alessandro, U; De Crop, M; Halidou, T; Kalanda, G; Menten, J; Mulenga, M; Mutabingwa, T; Mwakazanga, D; Mwapasa, V; Nambozi, M; Phiri, LK; Ravinetto, R; Schurmans, C; Tagbor, H; Thriemer, K; Traore, M; Valea, I; Van Geertruyden, JP | 1 |
Blomberg, B; Heggheim, Å; Mørch, K | 1 |
Day, NP; Hanpithakpon, W; Hlaing, N; Kloprogge, F; McGready, R; Nosten, F; Phyo, AP; Rijken, MJ; Tarning, J; Than, HH; White, NJ; Zin, NT | 1 |
Adedeji, ON; Ademowo, OG; Bolaji, OO; Falade, CO; Osonuga, OA | 1 |
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Janse, CJ; Kos, J; Lugt, CB; Waters, AP | 1 |
Adams, PA; Berman, PA; Egan, TJ; Marsh, PJ; Silver, J | 1 |
Feng, ZM; Lin, PY; Pan, JQ; Xiao, LY; Zhang, D | 1 |
Boulard, Y; Caillard, V; Fleck, SL; Glénat, C; Landau, I; Peters, W; Robinson, BL; Thévin, F | 1 |
Andrial, M; Chalermrut, K; Looareesuwan, S; Molunto, W; Olliaro, P; Wilairatana, P | 1 |
Linnau, KF; Looaresuwan, S; Rumpold, H; Wenisch, C | 1 |
Nosten, F; van Vugt, M; White, NJ | 1 |
Gomes, M; Tabusso, G | 1 |
Folb, P; Gomes, M; Olliaro, P | 1 |
Ducret, JP; Essono, E; Lohoue, J; Ravinet, L; Same-Ekobo, A | 1 |
Chang, HL; Chang, SC; Chen, YC; Fang, CT; Hsieh, WC; Hsueh, PR; Hung, CC | 1 |
Peters, W; Robinson, BL | 1 |
Ding, DB; Li, GF; Shi, YL; Yang, JD; Zhao, JH | 1 |
Chantharaksri, U; Dangdoungjai, J; Looareesuiwan, S; Pipitaporn, B; Sibmooh, N; Udomsangpetch, R; Wilairatana, P | 1 |
Agbenyega, T; Agranoff, D; Appiah, JA; Bedu-Addo, G; Krishna, S; Mansor, SM; Navaratnam, V; Owusu-Ofori, AK; Planche, T; Ramanathan, S; Woodrow, C | 1 |
Bloland, PB; Ettling, M; Meek, S | 1 |
Ambroise-Thomas, P | 1 |
Rozendaal, J | 1 |
Ishiyama, A; Kohana, A; Manabe, C; Omura, S; Otoguro, K; Shiomi, K; Ui, H; Yamada, H | 1 |
Chen, L; Li, G; Lu, Y; Luo, Z | 1 |
Ginsburg, H; Hoshen, MB; Stein, WD | 1 |
Li, AY; Liu, X; Xie, PS; Xuan, WY; Zhao, Y | 1 |
Bunyaratvej, A; Butthep, P; Fucharoen, S; Yuthavong, Y | 1 |
Guo, XB | 1 |
Cai, Y; Li, AY; Xie, PS; Xuan, WY; Zhao, Y | 1 |
Feng, TG; Guo, XB; Li, GQ; Li, PS; Shi, WZ; Wang, HF; Zhang, SF | 1 |
Du, YL; Jiang, Q; Li, CS | 1 |
Li, ZL; Peters, W; Robinson, BL; Warhurst, DC | 1 |
Hall, IH; Lee, KH; Oswald, CB; Yokoi, T; Zhao, Y | 1 |
Gu, WG; Hou, HM; Jia, MH; Lei, TK; Li, AY; Liu, X; Xie, PS; Zhao, Y | 1 |
Li, GD | 1 |
43 review(s) available for artesunic acid and Infections, Plasmodium
Article | Year |
---|---|
Clinical management of Plasmodium knowlesi malaria.
Topics: Antimalarials; Artesunate; Humans; Malaria; Malaria, Falciparum; Plasmodium knowlesi | 2021 |
Pediatric Malaria: Global and North American Perspectives.
Topics: Acute Kidney Injury; Anemia; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Child; Child, Preschool; Female; Global Health; Humans; Infant; Malaria; Male; North America; Plasmodium; Respiratory Distress Syndrome; Travel | 2022 |
New Insights into Artesunate as a Pleiotropic Regulator of Innate and Adaptive Immune Cells.
Topics: Adaptive Immunity; Animals; Antimalarials; Artemisinins; Artesunate; Humans; Immune System Diseases; Immunity, Innate; Immunomodulation; Malaria | 2022 |
Therapeutic efficacy of artemether-lumefantrine, artesunate-amodiaquine and dihydroartemisinin-piperaquine in the treatment of uncomplicated Plasmodium falciparum malaria in Sub-Saharan Africa: A systematic review and meta-analysis.
Topics: Africa South of the Sahara; Amodiaquine; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Drug Combinations; Ethanolamines; Humans; Malaria; Malaria, Falciparum; Piperazines; Plasmodium falciparum; Quinolines | 2022 |
Drug-Drug Interactions of Artemisinin-Based Combination Therapies in Malaria Treatment: A Narrative Review of the Literature.
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Humans; Malaria; Malaria, Falciparum | 2022 |
Updates in central nervous system malaria: literature review and considerations.
Topics: Adult; Antimalarials; Artesunate; Central Nervous System; Child; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum | 2022 |
Diagnosis, Treatment, and Prevention of Malaria in the US: A Review.
Topics: Adult; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Humans; Malaria; Malaria, Falciparum; Travel; Travel-Related Illness; United States | 2022 |
Severe malaria.
Topics: Africa South of the Sahara; Anti-Bacterial Agents; Antimalarials; Artesunate; Child; Humans; Malaria | 2022 |
Pre-referral rectal artesunate: no cure for unhealthy systems.
Topics: Antimalarials; Artemisinins; Artesunate; Child; Humans; Malaria; Observational Studies as Topic; Randomized Controlled Trials as Topic; Referral and Consultation | 2023 |
The wrongful indictment of pre-referral rectal artesunate further delays the roll-out of this lifesaving drug.
Topics: Administration, Rectal; Antimalarials; Artemisinins; Artesunate; Humans; Malaria; Observational Studies as Topic; Pharmaceutical Preparations; Referral and Consultation | 2023 |
Systematic review of artesunate pharmacokinetics: Implication for treatment of resistant malaria.
Topics: Administration, Intravenous; Administration, Oral; Antimalarials; Artemisinins; Artesunate; Asia, Southeastern; Drug Monitoring; Drug Resistance; Humans; Malaria; Malaria, Falciparum | 2019 |
IV artesunate for severe malaria.
Topics: Administration, Intravenous; Animals; Antimalarials; Artesunate; Clinical Trials as Topic; Humans; Malaria; Severity of Illness Index | 2020 |
Drug treatment and prevention of malaria in pregnancy: a critical review of the guidelines.
Topics: Adult; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artesunate; Chloroquine; Drug Combinations; Female; Humans; Malaria; Parasitemia; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Quinine; Sulfadoxine | 2021 |
Malaria PK/PD and the Role Pharmacometrics Can Play in the Global Health Arena: Malaria Treatment Regimens for Vulnerable Populations.
Topics: Amodiaquine; Anti-HIV Agents; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Child, Preschool; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Female; Global Health; HIV Infections; Humans; Malaria; Malnutrition; Mefloquine; Models, Biological; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Quinolines; Sulfadoxine; Vulnerable Populations | 2021 |
The mechanisms of action of Plasmodium infection against cancer.
Topics: Animals; Artesunate; Cell Proliferation; Humans; Immune Checkpoint Inhibitors; Immunotherapy; Malaria; Mice; Neoplasms; Tumor Microenvironment | 2021 |
Artesunate to treat severe malaria in travellers: review of efficacy and safety and practical implications.
Topics: Antimalarials; Artemisinins; Artesunate; Humans; Malaria; Retrospective Studies; Travel | 2017 |
Intensive care in severe malaria: Report from the task force on tropical diseases by the World Federation of Societies of Intensive and Critical Care Medicine.
Topics: Acute Kidney Injury; Adult; Advisory Committees; Antimalarials; Artemisinins; Artesunate; Child; Critical Care; Female; Humans; Malaria; Male; Respiratory Distress Syndrome; Severity of Illness Index; Societies, Medical; Tropical Medicine | 2018 |
[Severe and complicated malaria].
Topics: Adult; Anemia, Hemolytic; Antimalarials; Artesunate; Child; Female; France; Humans; Malaria; Malaria, Falciparum; Pregnancy; Severity of Illness Index | 2019 |
Malaria.
Topics: Africa South of the Sahara; Amodiaquine; Animals; Anopheles; Antimalarials; Artemisinins; Artesunate; Asia, Southeastern; Chloroquine; Drug Administration Schedule; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Humans; Insecticide-Treated Bednets; Insecticides; Malaria; Malaria Vaccines; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Pregnancy; Pregnancy Complications, Infectious; Primary Prevention; Pyrimethamine; Quinine; Quinolines; Seasons; Sulfadoxine | 2014 |
Pre-referral rectal artesunate for severe malaria.
Topics: Administration, Rectal; Adult; Age Factors; Antimalarials; Artemisinins; Artesunate; Bangladesh; Child; Child, Preschool; Emergency Medical Services; Ghana; Humans; Infant; Malaria; Rural Health; Tanzania | 2014 |
Synthetic chemistry fuels interdisciplinary approaches to the production of artemisinin.
Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Drug Resistance, Microbial; Malaria; Molecular Structure; Plasmodium falciparum | 2015 |
Post-artesunate delayed haemolysis ‒ report of four cases and review of the literature.
Topics: Adult; Anemia, Hemolytic; Antimalarials; Artemisinins; Artesunate; Erythrocytes; Female; Hemolysis; Humans; Malaria; Male | 2015 |
Treatment regimens for pregnant women with falciparum malaria.
Topics: Antimalarials; Artemisinins; Artesunate; Drug Administration Schedule; Female; Humans; Injections, Intravenous; Malaria; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications, Parasitic; Pregnancy Trimesters; Severity of Illness Index; World Health Organization | 2016 |
The Treatment of Plasmodium knowlesi Malaria.
Topics: Antimalarials; Artemisinins; Artesunate; Asia, Southeastern; Chloroquine; Coinfection; Humans; Malaria; Malaria, Falciparum; Plasmodium knowlesi | 2017 |
Artemisinin-based combination therapy for treating uncomplicated malaria.
Topics: Antimalarials; Artemisinins; Artesunate; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Parasitemia; Pyrimethamine; Quinolines; Randomized Controlled Trials as Topic; Sulfadoxine | 2009 |
Toxicity of the antimalarial artemisinin and its dervatives.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Clinical Trials as Topic; Developing Countries; Dogs; Drug Administration Routes; Drug-Related Side Effects and Adverse Reactions; Humans; Malaria; Rabbits; Rats; Sesquiterpenes | 2010 |
Artesunate versus quinine for treating severe malaria.
Topics: Adult; Antimalarials; Artemisinins; Artesunate; Child; Humans; Injections, Intramuscular; Injections, Intravenous; Malaria; Quinine; Randomized Controlled Trials as Topic | 2011 |
Severe malaria: artesunate is now the standard treatment.
Topics: Adolescent; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Evidence-Based Medicine; Humans; Malaria; Severity of Illness Index | 2011 |
Artesunate versus quinine for treating severe malaria.
Topics: Adult; Antimalarials; Artemisinins; Artesunate; Child; Humans; Injections, Intramuscular; Injections, Intravenous; Malaria; Quinine; Randomized Controlled Trials as Topic | 2012 |
Adjunctive management of malaria.
Topics: Antimalarials; Artemisinins; Artesunate; Blood Transfusion; Fluid Therapy; Humans; Malaria; Malaria, Cerebral; Nitric Oxide | 2012 |
Estimating the needs for artesunate-based combination therapy for malaria case-management in Africa.
Topics: Adolescent; Adult; Africa; Age Factors; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Drug Costs; Drug Therapy, Combination; Humans; Infant; Malaria; Risk Factors; Sesquiterpenes | 2003 |
Antimalarial compounds: from bench to bedside.
Topics: Age Factors; Animals; Antimalarials; Artemisinins; Artesunate; Clinical Trials as Topic; Drug Combinations; Drug Design; Drug Resistance; Malaria; Plasmodium; Sesquiterpenes | 2003 |
New antimalarial drugs.
Topics: Aminoquinolines; Animals; Antimalarials; Artemisinins; Artesunate; Atovaquone; Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Design; Drug Resistance; Ethanolamines; Flavonoids; Fluorenes; Fosfomycin; Global Health; Humans; Lumefantrine; Malaria; Naphthoquinones; Naphthyridines; Plasmodium falciparum; Proguanil; Sesquiterpenes | 2003 |
[Combined antimalarial therapy using artemisinin].
Topics: Amodiaquine; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Doxycycline; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Mefloquine; Plasmodium; Pyrimethamine; Quinine; Sesquiterpenes; Sulfadoxine | 2004 |
Resisting resistance: dealing with the irrepressible problem of malaria.
Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Dapsone; Drug Combinations; Drug Resistance; Humans; Malaria; Proguanil; Sesquiterpenes | 2006 |
Malaria: severe, life threatening.
Topics: Acute Disease; Antimalarials; Artemether; Artemisinins; Artesunate; Humans; Malaria; Quinine; Sesquiterpenes | 2006 |
Rectal administration of artemisinin derivatives for the treatment of malaria.
Topics: Administration, Rectal; Area Under Curve; Artemether; Artemisinins; Artesunate; Humans; Malaria; Sesquiterpenes | 2007 |
Artesunate versus quinine for treating severe malaria.
Topics: Adult; Antimalarials; Artemisinins; Artesunate; Child; Humans; Injections, Intramuscular; Injections, Intravenous; Malaria; Quinine; Randomized Controlled Trials as Topic; Sesquiterpenes | 2007 |
Assessment of the relative advantage of various artesunate-based combination therapies by a multi-treatment Bayesian random-effects meta-analysis.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Bayes Theorem; Chloroquine; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Malaria; Mefloquine; Pyrimethamine; Randomized Controlled Trials as Topic; Sesquiterpenes; Sulfadoxine; Treatment Outcome | 2007 |
Intrarectal artemisinin derivatives.
Topics: Absorption; Administration, Rectal; Adult; Antimalarials; Artemether; Artemisinins; Artesunate; Child; Humans; Malaria; Metabolic Clearance Rate; Sesquiterpenes; Suppositories | 1998 |
What role can public health institutions play in drug development for the poor? A case study of artesunate.
Topics: Africa; Antimalarials; Artemisinins; Artesunate; Drug and Narcotic Control; Drug Evaluation, Preclinical; Drug Industry; Endemic Diseases; Europe; Health Services Needs and Demand; Humans; International Cooperation; Malaria; Poverty; Public Health Practice; Research Support as Topic; Sesquiterpenes; United States; World Health Organization | 1998 |
Combination therapy for malaria in Africa: hype or hope?
Topics: Africa; Antimalarials; Artemisinins; Artesunate; Asia, Southeastern; Chloroquine; Cross-Cultural Comparison; Half-Life; Humans; Insecticide Resistance; Malaria; Mefloquine; Pyrimethamine; Self Medication; Sesquiterpenes; Sulfadoxine; Thailand | 2000 |
[Treatment of malaria: prevention of resistance by combinations of antimalarial agents].
Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Mefloquine; Naphthyridines; Plasmodium; Sesquiterpenes | 2000 |
61 trial(s) available for artesunic acid and Infections, Plasmodium
Article | Year |
---|---|
Effectiveness of pyronaridine-artesunate against Plasmodium malariae, Plasmodium ovale spp, and mixed-Plasmodium infections: a post-hoc analysis of the CANTAM-Pyramax trial.
Topics: Artesunate; Drug Combinations; Humans; Malaria; Naphthyridines; Plasmodium malariae; Plasmodium ovale | 2022 |
Overall and Gender-Specific Effects of Intermittent Preventive Treatment of Malaria with Artemisinin-Based Combination Therapies among Schoolchildren in Mali: A Three-Group Open Label Randomized Controlled Trial.
Topics: Amodiaquine; Anemia; Antimalarials; Artemisinins; Artesunate; Child; Drug Combinations; Drug Therapy, Combination; Female; Hemoglobins; Humans; Malaria; Malaria, Falciparum; Mali; Pyrimethamine; Sulfadoxine | 2022 |
Effectiveness of rectal artesunate as pre-referral treatment for severe malaria in children under 5 years of age: a multi-country observational study.
Topics: Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Humans; Infant, Newborn; Malaria; Referral and Consultation | 2022 |
Effectiveness of antimalarial drug combinations in treating concomitant urogenital schistosomiasis in malaria patients in Lambaréné, Gabon: A non-randomised event-monitoring study.
Topics: Amodiaquine; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artesunate; Drug Combinations; Ethanolamines; Gabon; Humans; Malaria; Malaria, Falciparum; Schistosomiasis haematobia | 2022 |
Effectiveness and safety of intermittent preventive treatment with dihydroartemisinin-piperaquine or artesunate-amodiaquine for reducing malaria and related morbidities in schoolchildren in Tanzania: a randomised controlled trial.
Topics: Amodiaquine; Antimalarials; Artesunate; Child; COVID-19; Drug Combinations; Hemoglobins; Humans; Incidence; Malaria; Malaria, Falciparum; Quinolines; Tanzania | 2023 |
Adherence to the referral advice after introduction of rectal artesunate for pre-referral treatment of severe malaria at the community level: a noninferiority trial in the Democratic Republic of the Congo.
Topics: Administration, Rectal; Adult; Antimalarials; Artesunate; Caregivers; Child, Preschool; Democratic Republic of the Congo; Female; Humans; Infant; Infant, Newborn; Malaria; Male; Middle Aged; Mothers; Pre-Exposure Prophylaxis; Referral and Consultation; Treatment Adherence and Compliance; Young Adult | 2019 |
Impact of intermittent preventive treatment of malaria in pregnancy with dihydroartemisinin-piperaquine versus sulfadoxine-pyrimethamine on the incidence of malaria in infancy: a randomized controlled trial.
Topics: Adult; Antimalarials; Artesunate; Double-Blind Method; Drug Combinations; Female; Humans; Incidence; Infant; Infant, Newborn; Malaria; Male; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Sulfadoxine; Young Adult | 2020 |
Efficacy, Safety and Tolerability of Pyronaridine-artesunate in Asymptomatic Malaria-infected Individuals: a Randomized Controlled Trial.
Topics: Antimalarials; Artesunate; Drug Combinations; Humans; Malaria; Malaria, Falciparum; Naphthyridines; Plasmodium falciparum; Treatment Outcome | 2022 |
A randomized controlled trial of dihydroartemisinin-piperaquine, artesunate-mefloquine and extended artemether-lumefantrine treatments for malaria in pregnancy on the Thailand-Myanmar border.
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Drug Therapy, Combination; Female; Humans; Infant, Newborn; Malaria; Malaria, Falciparum; Mefloquine; Myanmar; Pregnancy; Premature Birth; Quinolines; Thailand | 2021 |
Artemisinin-based combination therapy in pregnant women in Zambia: efficacy, safety and risk of recurrent malaria.
Topics: Adolescent; Adult; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Drug Combinations; Ethanolamines; Female; Fluorenes; Humans; Malaria; Mefloquine; Pregnancy; Quinolines; Recurrence; Risk; Treatment Outcome; Young Adult; Zambia | 2017 |
Intravenous artesunate plus Artemisnin based Combination Therapy (ACT) or intravenous quinine plus ACT for treatment of severe malaria in Ugandan children: a randomized controlled clinical trial.
Topics: Administration, Intravenous; Antimalarials; Artemisinins; Artesunate; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Kaplan-Meier Estimate; Malaria; Male; Quinine; Risk Factors; Treatment Outcome; Uganda | 2017 |
A Competing-Risk Approach for Modeling Length of Stay in Severe Malaria Patients in South-East Asia and the Implications for Planning of Hospital Services.
Topics: Adult; Antimalarials; Artesunate; Asia, Southeastern; Female; Humans; Length of Stay; Malaria; Male; Quinine; Retrospective Studies; Young Adult | 2018 |
Pyronaridine-artesunate or dihydroartemisinin-piperaquine versus current first-line therapies for repeated treatment of uncomplicated malaria: a randomised, multicentre, open-label, longitudinal, controlled, phase 3b/4 trial.
Topics: Adolescent; Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Child; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Longitudinal Studies; Malaria; Male; Naphthyridines; Quinolines; Young Adult | 2018 |
An artesunate-containing antimalarial treatment regimen did not suppress cytomegalovirus viremia.
Topics: Adolescent; Antimalarials; Antiviral Agents; Artemisinins; Artesunate; Child; Child, Preschool; Cytomegalovirus; Cytomegalovirus Infections; DNA, Viral; Drug Therapy, Combination; Female; Humans; Infant; Malaria; Male; Real-Time Polymerase Chain Reaction; Treatment Outcome; Uganda; Viremia | 2013 |
Delayed hemolysis after treatment with parenteral artesunate in African children with severe malaria--a double-center prospective study.
Topics: Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Female; Follow-Up Studies; Gabon; Ghana; Hemolysis; Humans; Infant; Malaria; Male; Prospective Studies | 2014 |
A study protocol for a randomised open-label clinical trial of artesunate-mefloquine versus chloroquine in patients with non-severe Plasmodium knowlesi malaria in Sabah, Malaysia (ACT KNOW trial).
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Female; Humans; Malaria; Malaysia; Male; Mefloquine; Plasmodium knowlesi; Research Design; Severity of Illness Index | 2014 |
Safe and efficacious artemisinin-based combination treatments for African pregnant women with malaria: a multicentre randomized control trial.
Topics: Adult; Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Birth Weight; Burkina Faso; Drug Combinations; Ethanolamines; Female; Fetal Development; Fluorenes; Follow-Up Studies; Ghana; Humans; Infant, Newborn; Malaria; Malawi; Mefloquine; Placentation; Pregnancy; Pregnancy Complications, Parasitic; Prenatal Exposure Delayed Effects; Quinolines; Zambia | 2015 |
Opposite malaria and pregnancy effect on oral bioavailability of artesunate - a population pharmacokinetic evaluation.
Topics: Administration, Intravenous; Administration, Oral; Antimalarials; Artemisinins; Artesunate; Biological Availability; Female; Humans; Malaria; Models, Biological; Postpartum Period; Pregnancy; Pregnancy Complications, Parasitic | 2015 |
Validation and pharmacokinetic application of a high-performance liquid chromatographic technique for determining the concentrations of amodiaquine and its metabolite in plasma of patients treated with oral fixed-dose amodiaquine-artesunate combination in
Topics: Administration, Oral; Adult; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Chromatography, High Pressure Liquid; Drug Combinations; Female; Humans; Malaria; Malaria, Falciparum; Male; Nigeria; Young Adult | 2015 |
Safety and efficacy of re-treatments with pyronaridine-artesunate in African patients with malaria: a substudy of the WANECAM randomised trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Artesunate; Burkina Faso; Child; Child, Preschool; Drug Combinations; Female; Guinea; Humans; Infant; Malaria; Male; Mali; Middle Aged; Naphthyridines; Plasmodium; Retreatment; Treatment Outcome; Young Adult | 2016 |
Artesunate-mefloquine versus chloroquine for treatment of uncomplicated Plasmodium knowlesi malaria in Malaysia (ACT KNOW): an open-label, randomised controlled trial.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Therapy, Combination; Female; Humans; Malaria; Malaysia; Male; Mefloquine; Middle Aged; Plasmodium knowlesi; Young Adult | 2016 |
Population Pharmacokinetics of Pyronaridine in Pediatric Malaria Patients.
Topics: Adolescent; Antimalarials; Area Under Curve; Artemisinins; Artesunate; Child; Child, Preschool; Female; Humans; Infant; Malaria; Malaria, Falciparum; Malaria, Vivax; Male; Models, Theoretical; Naphthyridines | 2015 |
Factors influencing willingness to participate in new drug trial studies: a study among parents whose children were recruited into these trials in northern Ghana.
Topics: Administration, Rectal; Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Child; Community Health Services; Female; Ghana; Humans; Informed Consent; Malaria; Male; Middle Aged; Motivation; Parents; Patient Participation | 2016 |
Effect of quinine and artesunate combination therapy on platelet count of children with severe malaria.
Topics: Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Coma; Drug Therapy, Combination; Female; Humans; Incidence; Infant; Malaria; Male; Platelet Count; Quinine; Thrombocytopenia; Treatment Outcome | 2017 |
Compliance With Referral Advice After Treatment With Prereferral Rectal Artesunate: A Study in 3 Sub-Saharan African Countries.
Topics: Administration, Rectal; Africa South of the Sahara; Antimalarials; Artemisinins; Artesunate; Child, Preschool; Female; Humans; Infant; Malaria; Male; Patient Acceptance of Health Care; Patient Compliance; Referral and Consultation | 2016 |
Quantifying and Valuing Community Health Worker Time in Improving Access to Malaria Diagnosis and Treatment.
Topics: Adult; Antimalarials; Artemisinins; Artesunate; Burkina Faso; Community Health Workers; Diagnostic Tests, Routine; Female; Humans; Malaria; Male; Middle Aged; Nigeria; Rural Population; Surveys and Questionnaires; Time Factors; Uganda; Young Adult | 2016 |
Pre-referral Rectal Artesunate Treatment by Community-Based Treatment Providers in Ghana, Guinea-Bissau, Tanzania, and Uganda (Study 18): A Cluster-Randomized Trial.
Topics: Administration, Rectal; Antimalarials; Artemisinins; Artesunate; Child, Preschool; Community Health Workers; Female; Ghana; Guinea-Bissau; Humans; Infant; Malaria; Male; Referral and Consultation; Tanzania; Uganda | 2016 |
An open label, randomised trial of artesunate+amodiaquine, artesunate+chlorproguanil-dapsone and artemether-lumefantrine for the treatment of uncomplicated malaria.
Topics: Amodiaquine; Antimalarials; Artemether; Artemisinins; Artesunate; Child; Child, Preschool; Dapsone; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Infant; Lumefantrine; Malaria; Male; Polymerase Chain Reaction; Proguanil; Treatment Outcome | 2008 |
Efficacy, safety and tolerability of artesunate-mefloquine in the treatment of uncomplicated Plasmodium falciparum malaria in four geographic zones of Nigeria.
Topics: Antimalarials; Artemisinins; Artesunate; Drug Therapy, Combination; Humans; Malaria; Mefloquine; Nigeria; Parasitemia; Rural Population; Time Factors | 2008 |
Seasonal intermittent preventive treatment for the prevention of anaemia and malaria in Ghanaian children: a randomized, placebo controlled trial.
Topics: Amodiaquine; Anemia; Antimalarials; Artemisinins; Artesunate; Child, Preschool; Drug Combinations; Ghana; Humans; Infant; Kaplan-Meier Estimate; Malaria; Placebos; Pyrimethamine; Seasons; Sulfadoxine | 2008 |
Cost-effectiveness of artesunate for the treatment of severe malaria.
Topics: Antimalarials; Artemisinins; Artesunate; Asia, Southeastern; Cost-Benefit Analysis; Drug Costs; Health Care Costs; Humans; Malaria; Quinine; Treatment Outcome | 2009 |
Randomized trial of artesunate+amodiaquine, sulfadoxine-pyrimethamine+amodiaquine, chlorproguanal-dapsone and SP for malaria in pregnancy in Tanzania.
Topics: Adult; Amodiaquine; Artemisinins; Artesunate; Dapsone; Drug Combinations; Drug Therapy, Combination; Female; Humans; Malaria; Pregnancy; Pregnancy Complications, Parasitic; Proguanil; Pyrimethamine; Sulfadoxine; Tanzania; Young Adult | 2009 |
Population pharmacokinetics of artesunate and amodiaquine in African children.
Topics: Africa; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Biological Availability; Biotransformation; Child, Preschool; Drug Combinations; Female; Humans; Infant; Malaria; Male; Plasma; Prospective Studies; Time Factors; Treatment Outcome | 2009 |
Azithromycin plus artesunate versus artemether-lumefantrine for treatment of uncomplicated malaria in Tanzanian children: a randomized, controlled trial.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Azithromycin; Child, Preschool; Drug Therapy, Combination; Ethanolamines; Female; Fever of Unknown Origin; Fluorenes; Humans; Infant; Lumefantrine; Malaria; Male; Tanzania; Treatment Outcome | 2009 |
Effectiveness of combined intermittent preventive treatment for children and timely home treatment for malaria control.
Topics: Adult; Amodiaquine; Animals; Antimalarials; Artemisinins; Artesunate; Caregivers; Child, Preschool; Drug Administration Schedule; Female; Fever; Ghana; Humans; Infant; Malaria; Male; Parasitemia; Plasmodium falciparum; Prevalence; Surveys and Questionnaires; Time Factors; Treatment Outcome | 2009 |
Intermittent preventive treatment in infants for the prevention of malaria in rural Western kenya: a randomized, double-blind placebo-controlled trial.
Topics: Anemia; Antimalarials; Artemisinins; Artesunate; Dapsone; Double-Blind Method; Drug Combinations; Humans; Incidence; Infant; Kenya; Malaria; Premedication; Proguanil; Pyrimethamine; Sulfadoxine; Treatment Outcome | 2010 |
Use of area under the curve to evaluate the effects of antimalarial drugs on malaria-associated anemia after treatment.
Topics: Amodiaquine; Anemia; Antimalarials; Area Under Curve; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Child; Child, Preschool; Drug Combinations; Ethanolamines; Female; Fluorenes; Hematocrit; Humans; Infant; Malaria; Malaria, Falciparum; Male; Mefloquine; Nigeria; Plasmodium falciparum | 2011 |
Incidence of malaria and efficacy of combination antimalarial therapies over 4 years in an urban cohort of Ugandan children.
Topics: Amodiaquine; Antimalarials; Artemether; Artemisinins; Artesunate; Child; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Incidence; Infant; Lumefantrine; Malaria; Male; Pyrimethamine; Sulfadoxine; Treatment Outcome; Uganda | 2010 |
Artesunate suppositories: an option for severe malaria.
Topics: Antimalarials; Artemisinins; Artesunate; Child; Double-Blind Method; Humans; Malaria; Suppositories | 2010 |
Cost effectiveness of seasonal intermittent preventive treatment using amodiaquine & artesunate or sulphadoxine-pyrimethamine in Ghanaian children.
Topics: Amodiaquine; Anemia; Antimalarials; Artemisinins; Artesunate; Child, Preschool; Cost-Benefit Analysis; Drug Combinations; Ghana; Humans; Infant; Malaria; Preventive Health Services; Pyrimethamine; Seasons; Sulfadoxine | 2010 |
Artesunate dose escalation for the treatment of uncomplicated malaria in a region of reported artemisinin resistance: a randomized clinical trial.
Topics: Adolescent; Adult; Amebicides; Antimalarials; Artemisinins; Artesunate; Cambodia; Dose-Response Relationship, Drug; Drug Resistance; Female; Humans; Malaria; Male; Maximum Tolerated Dose; Neutropenia; Parasitemia; Young Adult | 2011 |
A cluster-randomized trial of mass drug administration with a gametocytocidal drug combination to interrupt malaria transmission in a low endemic area in Tanzania.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Endemic Diseases; Female; Humans; Infant; Malaria; Male; Microscopy; Middle Aged; Parasitemia; Placebos; Primaquine; Pyrimethamine; Sulfadoxine; Tanzania; Treatment Outcome; Young Adult | 2011 |
Effects of amodiaquine and artesunate on sulphadoxine-pyrimethamine pharmacokinetic parameters in children under five in Mali.
Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Blood Chemical Analysis; Child, Preschool; Drug Combinations; Drug Interactions; Female; Half-Life; Humans; Infant; Malaria; Male; Mali; Pyrimethamine; Sulfadoxine | 2011 |
Pharmacokinetics and pharmacodynamics of intravenous artesunate during severe malaria treatment in Ugandan adults.
Topics: Adult; Antimalarials; Artemisinins; Artesunate; Chromatography, Liquid; Female; Humans; Injections, Intravenous; Malaria; Male; Plasma; Tandem Mass Spectrometry; Uganda | 2012 |
Glucose-6-phosphate dehydrogenase deficiency, chlorproguanil-dapsone with artesunate and post-treatment haemolysis in African children treated for uncomplicated malaria.
Topics: Africa South of the Sahara; Anemia, Hemolytic; Antimalarials; Artemisinins; Artesunate; Case-Control Studies; Child, Preschool; Dapsone; Drug Combinations; Drug Therapy, Combination; Glucosephosphate Dehydrogenase Deficiency; Humans; Infant; Malaria; Male; Proguanil | 2012 |
A longitudinal trial comparing chloroquine as monotherapy or in combination with artesunate, azithromycin or atovaquone-proguanil to treat malaria.
Topics: Antimalarials; Artemisinins; Artesunate; Atovaquone; Azithromycin; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Endpoint Determination; Female; Genotyping Techniques; Humans; Infant; Longitudinal Studies; Malaria; Male; Proguanil | 2012 |
Randomized, open-label trial of primaquine against vivax malaria relapse in Indonesia.
Topics: Adult; Antimalarials; Artemisinins; Artesunate; Drug Administration Schedule; Drug Dosage Calculations; Drug Resistance; Drug Therapy, Combination; Humans; Indonesia; Malaria; Malaria, Vivax; Male; Military Personnel; Plasmodium vivax; Primaquine; Quinine; Quinolines; Secondary Prevention | 2013 |
Evidence for the efficacy of artesunate in asymptomatic Plasmodium malariae infections.
Topics: Adolescent; Animals; Artemisinins; Artesunate; Child; Double-Blind Method; Female; Humans; Malaria; Male; Plasmodium malariae; Sesquiterpenes | 2002 |
Disposition of artesunate and dihydroartemisinin after administration of artesunate suppositories in children from Papua New Guinea with uncomplicated malaria.
Topics: Aging; alpha-Thalassemia; Antimalarials; Artemisinins; Artesunate; Body Weight; Child; Chromatography, High Pressure Liquid; Female; Genotype; Half-Life; Humans; Malaria; Male; Models, Statistical; Papua New Guinea; Population; Sesquiterpenes; Sex Characteristics; Spectrometry, Mass, Electrospray Ionization; Suppositories; Tissue Distribution | 2004 |
Investigation of bioavailability, pharmacokinetics and safety of new pediatric formulations of artesunate and mefloquine.
Topics: Administration, Oral; Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Biological Availability; Drug Therapy, Combination; Humans; Malaria; Male; Mefloquine; Pediatrics; Sesquiterpenes | 2005 |
Antischistosomal efficacy of artesunate combination therapies administered as curative treatments for malaria attacks.
Topics: Amodiaquine; Animals; Anthelmintics; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Humans; Infant; Malaria; Pilot Projects; Pyrimethamine; Schistosoma haematobium; Schistosomiasis haematobia; Sesquiterpenes; Sulfadoxine; Treatment Outcome | 2007 |
Artesunate + amodiaquine and artesunate + sulphadoxine-pyrimethamine for treatment of uncomplicated malaria in Democratic Republic of Congo: a clinical trial with determination of sulphadoxine and pyrimethamine-resistant haplotypes.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Artesunate; Child, Preschool; Democratic Republic of the Congo; DNA, Protozoan; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Haplotypes; Humans; Infant; Malaria; Malaria, Falciparum; Male; Plasmodium; Polymerase Chain Reaction; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Outcome | 2006 |
A comparative study on the efficacy of artesunate plus sulphadoxine/pyrimethamine versus artemether-lumefantrine in eastern Sudan.
Topics: Adolescent; Adult; Animals; Antigens, Protozoan; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Genotype; Humans; Malaria; Male; Merozoite Surface Protein 1; Plasmodium falciparum; Protozoan Proteins; Pyrimethamine; Sesquiterpenes; Sudan; Sulfadoxine; Treatment Outcome | 2007 |
Primaquine clears submicroscopic Plasmodium falciparum gametocytes that persist after treatment with sulphadoxine-pyrimethamine and artesunate.
Topics: Adolescent; Animals; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Drug Combinations; Female; Humans; Malaria; Malaria, Falciparum; Male; Plasmodium falciparum; Primaquine; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Tanzania; Treatment Outcome | 2007 |
High risk of neutropenia in HIV-infected children following treatment with artesunate plus amodiaquine for uncomplicated malaria in Uganda.
Topics: Amodiaquine; Anti-HIV Agents; Antimalarials; Artemisinins; Artesunate; Chemoprevention; Child; Child, Preschool; Drug Therapy, Combination; HIV Infections; Humans; Infant; Malaria; Neutropenia; Sesquiterpenes; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination; Uganda | 2008 |
Antimalarial efficacy and mode of action of qinghaosu and its derivatives in experimental models. China Cooperative Research Group on qinghaosu and its derivatives as antimalarials.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Erythrocytes; Malaria; Mice; Multicenter Studies as Topic; Plasmodium; Sesquiterpenes | 1982 |
Clinical studies on the treatment of malaria with qinghaosu and its derivatives. China Cooperative Research Group on qinghaosu and its derivatives as antimalarials.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Humans; Malaria; Multicenter Studies as Topic; Plasmodium falciparum; Plasmodium vivax; Sesquiterpenes | 1982 |
A comparative clinical trial of sequential treatments of severe malaria with artesunate suppository followed by mefloquine in Thailand.
Topics: Administration, Oral; Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Drug Therapy, Combination; Female; Humans; Malaria; Malaria, Cerebral; Male; Mefloquine; Middle Aged; Sesquiterpenes; Single-Blind Method; Suppositories; Thailand | 1997 |
[Rapid resolution of Plasmodium ovale malarial attacks using artesunate (Arsumax)].
Topics: Acute Disease; Adolescent; Adult; Anemia; Animals; Antimalarials; Artemisinins; Artesunate; Cameroon; Fever; Humans; Malaria; Middle Aged; Parasitemia; Plasmodium; Reticulocytes; Sesquiterpenes; Time Factors; Vertigo | 1999 |
Effect of artemisinin on lipid peroxidation and fluidity of the erythrocyte membrane in malaria.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Cyclic N-Oxides; Deferoxamine; Double-Blind Method; Erythrocyte Membrane; Humans; Lipid Peroxidation; Malaria; Malaria, Falciparum; Membrane Fluidity; Plasmodium falciparum; Sesquiterpenes; Thiobarbituric Acid Reactive Substances | 2000 |
Bioavailability and preliminary clinical efficacy of intrarectal artesunate in Ghanaian children with moderate malaria.
Topics: Administration, Rectal; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Female; Follow-Up Studies; Ghana; Humans; Infant; Injections, Intravenous; Malaria; Malaria, Cerebral; Male; Sesquiterpenes | 2001 |
273 other study(ies) available for artesunic acid and Infections, Plasmodium
Article | Year |
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MEFAS, a hybrid of artesunate-mefloquine active against asexual stages of Plasmodium vivax in field isolates, inhibits malaria transmission.
Topics: Animals; Antimalarials; Artesunate; Humans; Malaria; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Plasmodium falciparum; Plasmodium vivax | 2021 |
Cross-sectional study to predict subnational levels of health workers' knowledge about severe malaria treatment in Kenya.
Topics: Antimalarials; Artesunate; Bayes Theorem; Cross-Sectional Studies; Humans; Kenya; Malaria | 2022 |
Delayed autoimmune haemolytic anaemia after artesunate therapy for severe malaria.
Topics: Anemia, Hemolytic, Autoimmune; Antimalarials; Artesunate; Humans; Malaria; Malaria, Falciparum; Male; Middle Aged | 2022 |
Readiness of the Kenyan public health sector to provide pre-referral care for severe paediatric malaria.
Topics: Antimalarials; Artesunate; Child; Humans; Kenya; Malaria; Public Health; Referral and Consultation | 2022 |
Artesunate monotherapy versus artesunate plus quinine combination therapy for treatment of imported severe malaria: a TropNet retrospective cohort study.
Topics: Adult; Antimalarials; Artemisinins; Artesunate; Child; Drug Therapy, Combination; Fever; Humans; Malaria; Malaria, Falciparum; Quinine; Retrospective Studies | 2022 |
Parvovirus B19-associated transient aplastic crisis following P. falciparum malaria and post-artesunate delayed haemolysis in a returning traveller.
Topics: Artesunate; Hemolysis; Humans; Malaria; Malaria, Falciparum; Parvovirus B19, Human | 2022 |
Dimeric Artesunate Glycerophosphocholine Conjugate Nano-Assemblies as Slow-Release Antimalarials to Overcome Kelch 13 Mutant Artemisinin Resistance.
Topics: Antimalarials; Artemisinins; Artesunate; Cryoelectron Microscopy; Drug Resistance; Humans; Liposomes; Malaria; Malaria, Falciparum; Plasmodium falciparum | 2022 |
Artesunate Resistance - An Emerging Threat.
Topics: Adult; Antimalarials; Artesunate; Drug Resistance; Female; Humans; Malaria; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Pregnancy; Vomiting | 2022 |
Artesunate-amodiaquine and artemether-lumefantrine for the treatment of uncomplicated falciparum malaria in Liberia: in vivo efficacy and frequency of molecular markers.
Topics: Amodiaquine; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artesunate; Child; Chloroquine; DNA Copy Number Variations; Female; Humans; Liberia; Malaria; Malaria, Falciparum; Membrane Transport Proteins; Plasmodium falciparum; Pregnancy | 2022 |
Beneficial interaction between Ficus platyphylla and artesunate on cytokines TNF-α and IL-10 and oxidative stress in Plasmodium berghei-infected mice.
Topics: Animals; Antimalarials; Artesunate; Cytokines; Drug Combinations; Ficus; Interleukin-10; Malaria; Mice; Oxidative Stress; Parasitemia; Plasmodium berghei; Transferases; Tumor Necrosis Factor-alpha | 2022 |
Prevalence of malaria among febrile patients and assessment of efficacy of artemether-lumefantrine and artesunate-amodiaquine for uncomplicated malaria in Dolisie, Republic of the Congo.
Topics: Amodiaquine; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artesunate; Child; Congo; Drug Combinations; Fever; Humans; Malaria; Parasitemia; Prevalence | 2022 |
Prereferral rectal artesunate and referral completion among children with suspected severe malaria in the Democratic Republic of the Congo, Nigeria and Uganda.
Topics: Antimalarials; Artesunate; Child; Child, Preschool; Democratic Republic of the Congo; Humans; Malaria; Nigeria; Referral and Consultation; Uganda | 2022 |
[Malaria and its importance in travel medicine].
Topics: Antimalarials; Artesunate; Humans; Malaria; Malaria, Falciparum; Severity of Illness Index; Travel; Travel Medicine | 2022 |
Artesunate and dihydroartemisinin-piperaquine treatment failure in a severe Plasmodium falciparum malaria case imported from Republic of Côte d'Ivoire.
Topics: Aged; Antimalarials; Artemisinins; Artesunate; Cote d'Ivoire; Drug Combinations; Humans; Malaria; Malaria, Falciparum; Male; Piperazines; Plasmodium falciparum; Quinolines; Treatment Failure | 2022 |
Stakeholder perceptions on the deployment of multiple first-line therapies for uncomplicated malaria: a qualitative study in the health district of Kaya, Burkina Faso.
Topics: Amodiaquine; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Burkina Faso; Drug Combinations; Drug Therapy, Combination; Humans; Malaria; Malaria, Falciparum; Naphthyridines | 2022 |
Stopping prereferral rectal artesunate - a grave error.
Topics: Antimalarials; Artesunate; Humans; Malaria; Referral and Consultation | 2022 |
Prospective observational study to evaluate the clinical and biological safety profile of pyronaridine-artesunate in a rural health district in Burkina Faso.
Topics: Antimalarials; Artemisinins; Artesunate; Burkina Faso; Chemical and Drug Induced Liver Injury; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Humans; Malaria; Naphthyridines; Rural Health | 2022 |
Malaria Surveillance - United States, 2018.
Topics: Antimalarials; Artesunate; Biomarkers; Female; Humans; Malaria; Military Personnel; Population Surveillance; Pregnancy; United States | 2022 |
Post-artesunate Delayed Hemolysis in Patients With Severe Malaria in the United States-April 2019 Through July 2021.
Topics: Antimalarials; Artemisinins; Artesunate; Hemolysis; Humans; Malaria; Malaria, Falciparum; United States | 2023 |
Artesunate drug-loaded 2D nano-shuttle landing on RBCs infected with malaria parasites.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Erythrocytes; Lactate Dehydrogenases; Malaria; Nanostructures; Parasites; Pharmaceutical Preparations; Succinates | 2022 |
Food and Drug Administration Approval of Artesunate for Severe Malaria: Enough to Achieve Best Practice?
Topics: Antimalarials; Artemisinins; Artesunate; Humans; Malaria; United States; United States Food and Drug Administration | 2023 |
Malaria: Prevention, Diagnosis, and Treatment.
Topics: Animals; Artemisinins; Artesunate; Child; Female; Humans; Incidence; Malaria; Travel; United States | 2022 |
Key factors predicting suspected severe malaria case management and health outcomes: an operational study in the Democratic Republic of the Congo.
Topics: Antimalarials; Artesunate; Case Management; Child; Child, Preschool; Democratic Republic of the Congo; Humans; Infant; Malaria | 2022 |
Antioxidant activities of artesunate-procyanidin hybrid compound in erythrocyte and liver of Plasmodium berghei NK65-infected mice.
Topics: Animals; Antimalarials; Antioxidants; Artesunate; Erythrocytes; Liver; Malaria; Mice; Plasmodium berghei; Proanthocyanidins | 2023 |
Acceptability of pre-referral rectal artesunate for severe malaria in children under 5 years by health workers and caregivers in the Democratic Republic of the Congo, Nigeria and Uganda.
Topics: Antimalarials; Artemisinins; Artesunate; Caregivers; Child; Child, Preschool; Community Health Workers; Democratic Republic of the Congo; Humans; Malaria; Nigeria; Referral and Consultation; Uganda | 2022 |
Rectal artesunate as pre-referral treatment for severe malaria in sub-Saharan Africa: still a long way to go.
Topics: Africa South of the Sahara; Antimalarials; Artesunate; Humans; Malaria; Malaria, Falciparum; Referral and Consultation | 2023 |
Health system readiness and the implementation of rectal artesunate for severe malaria in sub-Saharan Africa: an analysis of real-world costs and constraints.
Topics: Africa South of the Sahara; Antimalarials; Artemisinins; Artesunate; Humans; Malaria | 2023 |
WHO should accelerate, not stall, rectal artesunate deployment for pre-referral treatment of severe malaria.
Topics: Administration, Rectal; Antimalarials; Artemisinins; Artesunate; Child; Humans; Malaria; Referral and Consultation; World Health Organization | 2023 |
Return to Travel in the Coronavirus Disease 2019 Pandemic Recovery Period and Implications for Imported Malaria: Reinforcing Prevention, Early Diagnosis, and Appropriate Treatment of Malaria.
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artesunate; COVID-19; COVID-19 Testing; Early Diagnosis; Humans; Malaria; Malaria, Falciparum; Pandemics; Travel; United States | 2023 |
Congenital severe malaria: Artesunate for successful and safe treatment in neonates: A case report.
Topics: Antimalarials; Artesunate; Humans; Infant, Newborn; Infant, Newborn, Diseases; Malaria; Malaria, Falciparum | 2023 |
Health worker compliance with severe malaria treatment guidelines in the context of implementing pre-referral rectal artesunate in the Democratic Republic of the Congo, Nigeria, and Uganda: An operational study.
Topics: Antimalarials; Artesunate; Child; Child, Preschool; Democratic Republic of the Congo; Humans; Malaria; Nigeria; Referral and Consultation; Uganda | 2023 |
Adherence to severe malaria treatment guidelines in children at a Ugandan regional hospital: a baseline assessment for a malaria treatment quality improvement project.
Topics: Antimalarials; Artesunate; Child; Child, Preschool; Female; Hospitals; Humans; Malaria; Male; Quality Improvement; Uganda | 2023 |
The five continuum of care criteria that should accompany rectal artesunate interventions: lessons learned from an implementation study in Malawi.
Topics: Antimalarials; Artesunate; Child; Community Health Workers; Continuity of Patient Care; Humans; Malaria; Malawi | 2023 |
Case Report: Severe Optic Neuritis after Multiple Episodes of Malaria in a Traveler to Africa.
Topics: Artesunate; Humans; Malaria; Male; Nigeria; Optic Neuritis; Steroids | 2023 |
Pre-referral rectal artesunate is no "magic bullet" in weak health systems.
Topics: Administration, Rectal; Antimalarials; Artemisinins; Artesunate; Bisacodyl; Child; Child, Preschool; Humans; Malaria; Referral and Consultation | 2023 |
The CARAMAL study could not assess the effectiveness of rectal artesunate in treating suspected severe malaria.
Topics: Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Humans; Malaria; Referral and Consultation | 2023 |
Use of artesunate in the treatment of severe imported malaria in France: review of the effectiveness and real-life safety in two French university hospitals.
Topics: Antimalarials; Artemisinins; Artesunate; France; Hospitals, University; Humans; Malaria; Malaria, Falciparum; Retrospective Studies | 2023 |
Rectal artesunate for severe malaria, implementation research, Zambia.
Topics: Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Community Health Workers; Humans; Malaria; Pilot Projects; Zambia | 2023 |
Case Report: Severe Plasmodium vivax Malaria after Splenectomy.
Topics: Artesunate; Humans; Malaria; Malaria, Vivax; Plasmodium falciparum; Plasmodium vivax; Splenectomy | 2023 |
Synthesis and Characterization of Dimeric Artesunate Glycerol Monocaprylate Conjugate and Formulation of Nanoemulsion Preconcentrate.
Topics: Artesunate; Drug Delivery Systems; Emulsions; Glycerol; Humans; Malaria; Nanoparticles; Polymers | 2023 |
Glutaraldehyde modified red blood cells delivering artesunate to the liver as a dual therapeutic and prophylactic antimalaria strategy.
Topics: Animals; Artesunate; Erythrocytes; Glutaral; Liver; Malaria; Mice | 2023 |
Evidence Based Optimal Dosing of Intravenous Artesunate in Children with Severe Falciparum Malaria.
Topics: Administration, Intravenous; Adolescent; Antimalarials; Artesunate; Bayes Theorem; Child; Humans; Malaria; Malaria, Falciparum | 2023 |
Investigation of new ferrocenyl-artesunate derivatives as antiparasitics.
Topics: Amides; Antimalarials; Antiparasitic Agents; Artesunate; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum | 2023 |
Antimalarial Agents Targeting Plasmodium falciparum Carbonic Anhydrase: Towards Artesunate Hybrid Compounds with Dual Mechanism of Action.
Topics: Animals; Antimalarials; Artesunate; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Humans; Malaria; Malaria, Falciparum; Mice; Plasmodium falciparum; Protein Isoforms | 2023 |
Variation in neutrophil levels and artemisinin-based combination therapy efficacy in West-Africa.
Topics: Africa; Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Drug Combinations; Ethanolamines; Humans; Malaria; Malaria, Falciparum; Neutropenia; Neutrophils; Parasitemia; Plasmodium falciparum; Prospective Studies | 2023 |
Assessing caregivers' perceptions of treatment-seeking for suspected severe malaria in the Democratic Republic of the Congo.
Topics: Anemia; Artesunate; Caregivers; Child; Cross-Sectional Studies; Democratic Republic of the Congo; Humans; Infant; Malaria; Patient Acceptance of Health Care | 2023 |
[Extracorporeal support treatment in severe malaria].
Topics: Adult; Antimalarials; Artesunate; Brain Diseases; Humans; Malaria; Malaria, Falciparum; Male | 2023 |
Favorable outcome without corticosteroids during post-artesunate delayed hemolysis with positive direct antiglobulin test in severe imported Plasmodium falciparum malaria, France.
Topics: Adrenal Cortex Hormones; Antimalarials; Artemisinins; Artesunate; Coombs Test; France; Hemolysis; Humans; Malaria; Malaria, Falciparum; Retrospective Studies | 2023 |
Rectal artesunate suppositories for the pre-referral treatment of suspected severe malaria.
Topics: Antimalarials; Artemisinins; Artesunate; Humans; Malaria; Referral and Consultation; Suppositories | 2023 |
[Artesunate and severe malaria in paediatrics].
Topics: Antimalarials; Artemisinins; Artesunate; Child; Europe; Humans; Malaria; Pediatrics | 2019 |
Determinants of post-malarial anemia in African children treated with parenteral artesunate.
Topics: Anemia; Antimalarials; Artesunate; Blood Transfusion; Child; Child, Preschool; Erythropoietin; Female; Humans; Infant; Infusions, Parenteral; Malaria; Male; Parasitemia | 2019 |
Use of rectal artesunate for severe malaria at the community level, Zambia.
Topics: Administration, Rectal; Antimalarials; Artesunate; Child, Preschool; Community Health Workers; Cross-Sectional Studies; Humans; Infant; Malaria; Medically Underserved Area; Pilot Projects; Severity of Illness Index; Transportation; Zambia | 2019 |
Anemia and transfusion requirements among Ugandan children with severe malaria treated with intravenous artesunate.
Topics: Administration, Intravenous; Anemia; Artesunate; Blood Transfusion; Child; Child, Preschool; Female; Humans; Malaria; Male; Prospective Studies; Uganda | 2020 |
Intravenous artesunate plus oral dihydroartemisinin-piperaquine or intravenous quinine plus oral quinine for optimum treatment of severe malaria: lesson learnt from a field hospital in Timika, Papua, Indonesia.
Topics: Administration, Intravenous; Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Drug Combinations; Female; Humans; Indonesia; Infant; Infant, Newborn; Malaria; Male; Middle Aged; Quinine; Quinolines; Retrospective Studies; Young Adult | 2019 |
Delayed haemolysis after treatment with intravenous artesunate in patients with severe malaria in India.
Topics: Administration, Intravenous; Adolescent; Adult; Anemia, Hemolytic; Antimalarials; Artesunate; Child; Child, Preschool; Female; Hemolysis; Humans; India; Infant; Malaria; Male; Middle Aged; Prospective Studies; Time Factors; Young Adult | 2020 |
The End of the Artemisinin Era-We Should Aim at Malaria Eradication in Asia Using Free, Effective Treatment.
Topics: Amodiaquine; Artemisinins; Artesunate; Asia; Cambodia; Humans; Malaria; Plasmodium falciparum | 2021 |
Clinical and In Vitro Resistance of Plasmodium falciparum to Artesunate-Amodiaquine in Cambodia.
Topics: Adult; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Asia; Cambodia; Child; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum; Prospective Studies | 2021 |
Post-malarial anemia in Mozambican children treated with quinine or artesunate: A retrospective observational study.
Topics: Administration, Intravenous; Adolescent; Anemia; Antimalarials; Artesunate; Child; Child, Preschool; Female; Humans; Infant; Malaria; Male; Mozambique; Quinine; Retrospective Studies | 2020 |
Malaria in the third trimester and maternal-perinatal outcome.
Topics: Adolescent; Adult; Anemia; Antimalarials; Artesunate; Asphyxia Neonatorum; Cameroon; Cohort Studies; Female; Fetal Death; Humans; Infant, Low Birth Weight; Infant, Newborn; Intensive Care Units, Neonatal; Malaria; Matched-Pair Analysis; Perinatal Death; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Trimester, Third; Premature Birth; Young Adult | 2020 |
Efficacy and Safety of Intravenous Artesunate in Children With Severe Imported Malaria.
Topics: Antimalarials; Artesunate; Child; Germany; Humans; Malaria; Retrospective Studies; Tertiary Care Centers | 2020 |
Increased Sensitivity of Plasmodium falciparum to Artesunate/Amodiaquine Despite 14 Years as First-Line Malaria Treatment, Zanzibar.
Topics: Amodiaquine; Antimalarials; Artesunate; Asia; Drug Combinations; Drug Resistance; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum; Protozoan Proteins; Tanzania | 2020 |
Predictors of health workers' knowledge about artesunate-based severe malaria treatment recommendations in government and faith-based hospitals in Kenya.
Topics: Artesunate; Clinical Competence; Drug Combinations; Health Personnel; Hospitals; Hospitals, Religious; Humans; Kenya; Malaria | 2020 |
Treatment Approved for Severe Malaria.
Topics: Adult; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child; Drug Combinations; Drug Monitoring; Humans; Injections, Intravenous; Malaria; Severity of Illness Index; Treatment Outcome | 2020 |
Maintaining focus on administering effective malaria treatment during the COVID-19 pandemic.
Topics: Administration, Intravenous; Antigens, Protozoan; Antimalarials; Artemether, Lumefantrine Drug Combination; Artesunate; COVID-19; Early Diagnosis; Early Medical Intervention; Humans; Malaria; Malaria, Falciparum; Microscopy; Point-of-Care Testing; Primaquine; Protozoan Proteins; SARS-CoV-2; Severity of Illness Index; South Africa | 2020 |
Intravenous Artesunate for the Treatment of Severe Imported Malaria: Implementation, Efficacy, and Safety in 1391 Patients.
Topics: Antimalarials; Artemisinins; Artesunate; Female; Hemolysis; Humans; Malaria; Malaria, Falciparum; Pregnancy | 2021 |
Effect of Body Weight and Age on the Pharmacokinetics of Dihydroartemisinin: Food and Drug Administration Basis for Dose Determination of Artesunate for Injection in Pediatric Patients With Severe Malaria.
Topics: Antimalarials; Artemisinins; Artesunate; Body Weight; Child; Humans; Malaria; Malaria, Falciparum; United States; United States Food and Drug Administration | 2021 |
Antiplasmodial activity of Ethanolic extract of Cassia spectabilis DC leaf and its inhibition effect in Heme detoxification.
Topics: Animals; Antimalarials; Artesunate; Cassia; Chloroquine; Heme; Ketones; Malaria; Male; Mice, Inbred BALB C; Phytotherapy; Piperidines; Plant Extracts; Plant Leaves; Plasmodium berghei; Plasmodium falciparum | 2021 |
Development and Validation of an
Topics: Adult; Africa; Antimalarials; Artesunate; Asia, Southeastern; Bayes Theorem; Child; Computer Simulation; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum | 2021 |
Pyronaridine-artesunate real-world safety, tolerability, and effectiveness in malaria patients in 5 African countries: A single-arm, open-label, cohort event monitoring study.
Topics: Adolescent; Adult; Africa; Antimalarials; Artesunate; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Drug Combinations; Female; Humans; Infant; Infant, Newborn; Liver Function Tests; Malaria; Male; Naphthyridines; Patient Safety; Product Surveillance, Postmarketing; Retrospective Studies; Time Factors; Treatment Outcome; Young Adult | 2021 |
Murine pharmacokinetics and antimalarial pharmacodynamics of dihydroartemisinin trimer self-assembled nanoparticles.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Malaria; Mice; Nanoparticles; Plasmodium yoelii; Rats | 2021 |
Safety and Effectiveness of Intravenous Artesunate for Treatment of Severe Malaria in the United States-April 2019 Through December 2020.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Female; Humans; Malaria; Malaria, Falciparum; Male; Middle Aged; United States; Young Adult | 2021 |
INFLUENCE OF ARTESUNATE COMBINATIVE THERAPY CO-ADMINISTRATION WITH RUTIN ON INFLAMMATORY CYTOKINES AND IMMUNOGLOBULINS IN PLASMODIUM BERGHEI-INFECTED MICE.
Topics: Animals; Antimalarials; Antioxidants; Artesunate; Cytokines; Drug Therapy, Combination; Immunoglobulins; Leukocyte Count; Leukocytes; Malaria; Male; Mice; Plasmodium berghei; Rutin | 2021 |
Effects of Artesunate on some biochemical parameters in pregnant albino Wistar rats challenged with lethal strain Plasmodium berghei NK65: Appreciating the activities of artemisinin drugs on key pregnancy hormone balance.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Female; Hormones; Malaria; Plasmodium berghei; Pregnancy; Pregnancy Complications, Infectious; Rats; Rats, Wistar | 2017 |
Adaptive immunity is essential in preventing recrudescence of Plasmodium yoelii malaria parasites after artesunate treatment.
Topics: Adaptive Immunity; Animals; Antimalarials; Artemisinins; Artesunate; B-Lymphocytes; CD4-Positive T-Lymphocytes; Disease Models, Animal; Drug Resistance; Female; Malaria; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Plasmodium yoelii; Recurrence | 2017 |
Measuring the
Topics: Adolescent; Adult; Aged; Antigens, Protozoan; Artemisinins; Artesunate; Cytosol; Demography; Erythrocyte Membrane; Erythrocytes; Female; Hemolysis; Humans; Malaria; Male; Middle Aged; Plasmodium falciparum; Protozoan Proteins; Quinine; Young Adult | 2017 |
Challenges in a product development partnership: a malaria treatment case study.
Topics: Antimalarials; Artemisinins; Artesunate; Brazil; Drug Combinations; Drug Design; Health Services Accessibility; Health Services Needs and Demand; Humans; Interviews as Topic; Malaria; Mefloquine; Public-Private Sector Partnerships | 2017 |
Artemisia annua dried leaf tablets treated malaria resistant to ACT and i.v. artesunate: Case reports.
Topics: Administration, Intravenous; Adolescent; Adult; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisia annua; Artemisinins; Artesunate; Child; Child, Preschool; Drug Combinations; Drug Resistance, Microbial; Ethanolamines; Female; Fluorenes; Humans; Infant; Malaria; Male; Middle Aged; Plant Leaves; Tablets; Treatment Outcome; Young Adult | 2017 |
Characterising the effect of antimalarial drugs on the maturation and clearance of murine blood-stage Plasmodium parasites in vivo.
Topics: Adoptive Transfer; Animals; Antimalarials; Artemisinins; Artesunate; Dose-Response Relationship, Drug; Erythrocytes; Female; Flow Cytometry; Malaria; Mefloquine; Mice; Mice, Inbred C57BL; Parasitemia; Phagocytes; Plasmodium berghei; Plasmodium yoelii | 2017 |
Artesunate-quercetin/luteolin dual drug nanofacilitated synergistic treatment for malaria: A plausible approach to overcome artemisinin combination therapy resistance.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Culicidae; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Female; Flavonoids; Humans; Lipids; Luteolin; Malaria; Models, Theoretical; Quercetin | 2017 |
Efficacy of Lophira alata Leaf Extract and its Combination with Artesunate in Mice Prior Exposed to Plasmodium berghei.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Malaria; Mice; Ochnaceae; Phytotherapy; Plant Extracts; Plant Leaves; Plants, Medicinal; Plasmodium berghei | 2018 |
Liposomes of dimeric artesunate phospholipid: A combination of dimerization and self-assembly to combat malaria.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Dimerization; Drug Carriers; Drug Liberation; Female; Glycerylphosphorylcholine; Humans; Liposomes; Malaria; Mice, Inbred BALB C; Nanoparticles; Particle Size | 2018 |
Tropical diseases in the ICU: A syndromic approach to diagnosis and treatment.
Topics: Artesunate; Azithromycin; Ceftriaxone; Child; Communicable Diseases; Critical Care; Dengue; Diagnosis, Differential; Doxycycline; Exanthema; Female; Fever; Geography; Humans; Intensive Care Units; Leptospirosis; Malaria; Male; Nervous System Diseases; Pregnancy; Shock, Hemorrhagic; Syndrome; Travel; Tropical Medicine; Typhoid Fever | 2018 |
Caregivers' compliance with referral advice: evidence from two studies introducing mRDTs into community case management of malaria in Uganda.
Topics: Adolescent; Antimalarials; Artemisinins; Artesunate; Caregivers; Case Management; Child; Child, Preschool; Community Health Workers; Diagnostic Tests, Routine; Female; Guideline Adherence; Humans; Infant; Malaria; Male; Randomized Controlled Trials as Topic; Referral and Consultation; Treatment Adherence and Compliance; Uganda | 2018 |
Age-Related Clinical Spectrum of Plasmodium knowlesi Malaria and Predictors of Severity.
Topics: Acute Kidney Injury; Age Factors; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Female; Humans; Infant; Kidney; Malaria; Malaysia; Male; Parasitemia; Plasmodium knowlesi; Prospective Studies; Severity of Illness Index | 2018 |
Community understanding of the concept of pre-referral treatment and how this impacts on referral related decision-making following the provision of rectal artesunate: a qualitative study in western Uganda.
Topics: Antimalarials; Artesunate; Caregivers; Case Management; Child, Preschool; Community Health Workers; Decision Making; Female; Focus Groups; Health Facilities; Humans; Interviews as Topic; Malaria; Male; Qualitative Research; Referral and Consultation; Uganda | 2018 |
Quantification of host-mediated parasite clearance during blood-stage Plasmodium infection and anti-malarial drug treatment in mice.
Topics: Animals; Antimalarials; Artesunate; Blood; Disease Models, Animal; Fluorescence; Malaria; Mefloquine; Mice; Models, Theoretical; Organisms, Genetically Modified; Parasite Load; Parasitemia; Plasmodium berghei; Staining and Labeling | 2018 |
Assessing the consistency assumptions underlying network meta-regression using aggregate data.
Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Bayes Theorem; Data Interpretation, Statistical; Humans; Malaria; Models, Statistical; Network Meta-Analysis; Odds Ratio; Quinine; Regression Analysis; Reproducibility of Results; Research Design | 2019 |
Artesunate-heparin conjugate based nanocapsules with improved pharmacokinetics to combat malaria.
Topics: Animals; Antimalarials; Artesunate; Drug Delivery Systems; Drug Liberation; Erythrocytes; Female; Hemolysis; Heparin; Humans; Malaria; Mice, Inbred BALB C; Nanocapsules; Plasmodium falciparum | 2019 |
Positive direct antiglobulin test in post-artesunate delayed haemolysis: more than a coincidence?
Topics: Administration, Intravenous; Adolescent; Adult; Anemia, Hemolytic; Antimalarials; Artesunate; Coombs Test; Female; Hemolysis; Humans; Malaria; Male; Middle Aged; Retrospective Studies; Spain | 2019 |
[Descriptive study of malaria cases in the paediatric population in a reference hospital in Valencia, Spain, between 1993 and 2015].
Topics: Adolescent; Age Distribution; Antimalarials; Artemisinins; Artesunate; Atovaquone; Child; Child, Preschool; Drug Combinations; Equatorial Guinea; Female; Hospitals, Community; Humans; Infant; Malaria; Male; Proguanil; Quinine; Quinolines; Retrospective Studies; Sex Distribution; Spain; Symptom Assessment | 2020 |
Hemolytic anemia in pediatric patients treated with artesunate for severe malaria.
Topics: Anemia, Hemolytic; Artesunate; Child; Humans; Malaria | 2020 |
Safety and efficacy of pyronaridine-artesunate in uncomplicated acute malaria: an integrated analysis of individual patient data from six randomized clinical trials.
Topics: Adolescent; Adult; Africa; Antimalarials; Artemisinins; Artesunate; Asia; Child; Child, Preschool; Clinical Trials, Phase III as Topic; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Infant; Malaria; Malaria, Falciparum; Malaria, Vivax; Male; Middle Aged; Naphthyridines; Randomized Controlled Trials as Topic; Treatment Outcome; Young Adult | 2013 |
Malaria burden and artemisinin resistance in the mobile and migrant population on the Thai-Myanmar border, 1999-2011: an observational study.
Topics: Antimalarials; Artemisinins; Artesunate; Climate; Community Health Workers; Cross-Sectional Studies; Drug Resistance; Female; Geography; Hospitalization; Humans; Malaria; Mefloquine; Myanmar; Plasmodium falciparum; Plasmodium vivax; Pregnancy; Pregnancy Complications, Parasitic; Prevalence; Rain; Reproducibility of Results; Temperature; Thailand; Transients and Migrants | 2013 |
Antimalarial potential of China 30 and Chelidonium 30 in combination therapy against lethal rodent malaria parasite: Plasmodium berghei.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chelidonium; Chloroquine; Cinchona; Female; Homeopathy; Malaria; Male; Materia Medica; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Phytotherapy; Plant Extracts; Plasmodium berghei; Pyrimethamine | 2013 |
Differential interactions of the broad spectrum drugs artemisinin, dihydroartemisinin and artesunate with serum albumin.
Topics: Animals; Artemisinins; Artesunate; Cattle; Drug Therapy, Combination; Hydrophobic and Hydrophilic Interactions; Malaria; Protein Binding; Serum Albumin | 2013 |
[From the Japanese Journal of Clinical Hematology, vol 54, no.5, May 2013, Picture in Clinical Hematology : Case of tropical malaria].
Topics: Adult; Antimalarials; Artemisinins; Artesunate; Drug Therapy, Combination; Erythrocytes; Humans; Malaria; Male; Polymerase Chain Reaction; Quinine; Travel; Treatment Outcome | 2013 |
Artesunate versus quinine in the treatment of severe imported malaria: comparative analysis of adverse events focussing on delayed haemolysis.
Topics: Adult; Anemia, Hemolytic; Antimalarials; Artemisinins; Artesunate; Drug-Related Side Effects and Adverse Reactions; Female; Germany; Human Migration; Humans; Malaria; Male; Middle Aged; Quinine; Retrospective Studies | 2013 |
Roll out of intraveneous artesunate under named patient programmes in the Netherlands, Belgium and France.
Topics: Administration, Intravenous; Antimalarials; Artemisinins; Artesunate; Belgium; France; Humans; Malaria; Netherlands; Rare Diseases | 2013 |
Oxidative stress and micronutrient therapy in malaria: an in vivo study in Plasmodium berghei infected mice.
Topics: Animals; Antioxidants; Artemisinins; Artesunate; Chloroquine; Dose-Response Relationship, Drug; Female; Hemolysis; Malaria; Male; Mice; Micronutrients; Oxidative Stress; Plasmodium berghei; Selenium; Vitamin A; Vitamin E; Zinc | 2013 |
In vitro and in vivo characterization of the antimalarial lead compound SSJ-183 in Plasmodium models.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Dose-Response Relationship, Drug; Drug Resistance; Female; Half-Life; Malaria; Mice; Oxazines; Plasmodium berghei; Plasmodium falciparum; Pyridines | 2013 |
Hypothesized cause of delayed hemolysis associated with intravenous artesunate.
Topics: Administration, Intravenous; Anemia; Anemia, Hemolytic; Animals; Antimalarials; Artemisinins; Artesunate; Erythrocytes; Haplorhini; Hemoglobins; Hemolysis; Humans; Malaria; Rats; Reticulocytes; Time Factors | 2014 |
[Malaria].
Topics: Antimalarials; Artemisinins; Artesunate; Atovaquone; Drug Therapy, Combination; Humans; Malaria; Prevalence; Proguanil | 2014 |
Disposition of amodiaquine and desethylamodiaquine in HIV-infected Nigerian subjects on nevirapine-containing antiretroviral therapy.
Topics: Adolescent; Adult; Amodiaquine; Anti-Retroviral Agents; Antimalarials; Antiretroviral Therapy, Highly Active; Artemisinins; Artesunate; Chromatography, High Pressure Liquid; Drug Interactions; Female; HIV Infections; Humans; Lamivudine; Malaria; Male; Middle Aged; Nevirapine; Nigeria; Plasma; Young Adult; Zidovudine | 2014 |
Formulation development and evaluation of the anti-malaria properties of sustained release artesunate-loaded solid lipid microparticles based on phytolipids.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Delayed-Action Preparations; Disease Models, Animal; Drug Carriers; Malaria; Mice; Microspheres; Particle Size; Plant Oils; Plasmodium berghei; Scattering, Small Angle; Soybean Oil; X-Ray Diffraction | 2015 |
Evaluation of haematological changes in Plasmodium-berghei-infected mice administered with aqueous extract of Phyllantus amarus.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Body Weight; Disease Models, Animal; Dose-Response Relationship, Drug; Erythrocyte Count; Female; Hematocrit; Leukocyte Count; Malaria; Male; Mice; Phyllanthus; Phytotherapy; Plant Extracts; Plant Leaves; Plants, Medicinal; Plasmodium berghei; Time Factors | 2013 |
Insights following change in drug policy: a descriptive study for antimalarial prescription practices in children of public sector health facilities in Jharkhand state of India.
Topics: Adolescent; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Cross-Sectional Studies; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Health Facilities; Humans; Inappropriate Prescribing; India; Infant; Malaria; Male; Practice Patterns, Physicians'; Prescriptions; Prospective Studies; Public Sector; Pyrimethamine; Retrospective Studies; Sulfadoxine | 2013 |
Introducing the concept of a new pre-referral treatment for severely ill febrile children at community level: a sociological approach in Guinea-Bissau.
Topics: Adult; Anti-Bacterial Agents; Antimalarials; Artemisinins; Artesunate; Drug Combinations; Female; Fever; Guinea-Bissau; Health Knowledge, Attitudes, Practice; Health Personnel; Humans; Infant; Infant, Newborn; Malaria; Mothers; Qualitative Research; Referral and Consultation; Rural Population; Suppositories; Surveys and Questionnaires | 2014 |
Plasmodium vivax and Plasmodium falciparum ex vivo susceptibility to anti-malarials and gene characterization in Rondônia, West Amazon, Brazil.
Topics: Adult; Antimalarials; Artemisinins; Artesunate; Brazil; Chloroquine; DNA, Protozoan; Drug Resistance; Female; Genotype; Humans; Inhibitory Concentration 50; Malaria; Male; Mefloquine; Membrane Transport Proteins; Middle Aged; Multidrug Resistance-Associated Proteins; Mutation, Missense; Parasitic Sensitivity Tests; Plasmodium falciparum; Plasmodium vivax; Protozoan Proteins | 2014 |
Human malaria in C57BL/6J mice: an in vivo model for chemotherapy studies.
Topics: Animals; Artemisinins; Artesunate; Disease Models, Animal; Drug Resistance, Multiple; Female; Humans; Malaria; Mice; Mice, Inbred C57BL; Parasitemia; Plasmodium falciparum | 2014 |
Needs-driven versus market-driven pharmaceutical innovation: the consortium for the development of a new medicine against malaria in Brazil.
Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Brazil; Drug Combinations; Drug Discovery; Drug Industry; Global Health; Health Care Sector; Health Services Needs and Demand; Humans; Internationality; Inventions; Malaria; Mefloquine; Neglected Diseases; Patents as Topic; Social Justice | 2014 |
Rapid response to selection, competitive release and increased transmission potential of artesunate-selected Plasmodium chabaudi malaria parasites.
Topics: Adaptation, Physiological; Animals; Antimalarials; Artemisinins; Artesunate; Dose-Response Relationship, Drug; Drug Resistance; Malaria; Mice; Plasmodium chabaudi | 2014 |
Synergistic effect of aqueous extract of Telfaria occidentalis on the biological activities of artesunate in Plasmodium berghei infected mice.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Cucurbita; Drug Combinations; Drug Synergism; Malaria; Mice; Phytotherapy; Plant Extracts; Plant Leaves; Plants, Medicinal; Plasmodium berghei; Rats; Rats, Wistar | 2013 |
Plasmodium malariae infection: a case of missed diagnosis.
Topics: Artemisinins; Artesunate; Azure Stains; Child; Chromatography, Affinity; Diagnostic Errors; Drug Combinations; Female; Humans; India; Malaria; Plasmodium malariae; Polymerase Chain Reaction; Primaquine; Pyrimethamine; Sulfadoxine; Treatment Outcome | 2014 |
Artesunate versus chloroquine infection-treatment-vaccination defines stage-specific immune responses associated with prolonged sterile protection against both pre-erythrocytic and erythrocytic Plasmodium yoelii infection.
Topics: Animals; Anopheles; Antibodies, Protozoan; Antimalarials; Artemisia; Artemisinins; Artesunate; Chloroquine; Erythrocytes; Female; Malaria; Malaria Vaccines; Mice; Mice, Inbred BALB C; Phytotherapy; Plasmodium yoelii; Sporozoites; Time Factors; Vaccines, Attenuated | 2014 |
Evaluation of dika wax-soybean oil-based artesunate-loaded lipospheres: in vitro-in vivo correlation studies.
Topics: Administration, Oral; Animals; Antimalarials; Artemisinins; Artesunate; Female; Hydrogen-Ion Concentration; Liposomes; Malaria; Male; Plant Oils; Rats; Rats, Wistar; Soybean Oil | 2014 |
Low-cost, high-speed identification of counterfeit antimalarial drugs on paper.
Topics: Antimalarials; Artemisinins; Artesunate; Asia, Southeastern; Colorimetry; Counterfeit Drugs; Humans; Malaria; Microfluidics; Paper; Tablets | 2014 |
Evaluation of a new handheld instrument for the detection of counterfeit artesunate by visual fluorescence comparison.
Topics: Antimalarials; Artemisinins; Artesunate; Chromatography, High Pressure Liquid; Confidence Intervals; Counterfeit Drugs; Fluorescence; Laos; Malaria; Optical Imaging; Sensitivity and Specificity | 2014 |
Efficacy of intravenous methylene blue, intravenous artesunate, and their combination in preclinical models of malaria.
Topics: Administration, Intravenous; Animals; Antimalarials; Aotidae; Artemisinins; Artesunate; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Therapy, Combination; Female; Macaca mulatta; Malaria; Male; Methylene Blue; Plasmodium berghei; Plasmodium cynomolgi; Rats; Rats, Sprague-Dawley; Treatment Outcome | 2014 |
Severe delayed hemolysis associated with regulated parenteral antimalarial drug.
Topics: Adult; Anemia, Hemolytic; Antimalarials; Artemisinins; Artesunate; Drug Administration Routes; Hemolysis; Humans; Malaria; Malaria, Falciparum; Male | 2015 |
An autochthonous case of severe Plasmodium knowlesi malaria in Thailand.
Topics: Antimalarials; Artemisinins; Artesunate; Humans; Malaria; Male; Middle Aged; Plasmodium knowlesi; Thailand | 2015 |
Preparedness for severe malaria.
Topics: Antimalarials; Artemisinins; Artesunate; Clinical Laboratory Techniques; Critical Illness; Hospitals; Humans; Malaria; Malaria, Falciparum; Microscopy; Patient Transfer; Quinine; Reagent Kits, Diagnostic; Surveys and Questionnaires; Time Factors | 2015 |
Delayed-onset hemolytic anemia in patients with travel-associated severe malaria treated with artesunate, France, 2011-2013.
Topics: Adolescent; Anemia, Hemolytic; Antimalarials; Artemisinins; Artesunate; Blood Transfusion; Female; France; History, 21st Century; Humans; Malaria; Male; Travel; Treatment Outcome | 2015 |
Replication of Plasmodium in reticulocytes can occur without hemozoin formation, resulting in chloroquine resistance.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Cytoplasm; Drug Resistance; Erythrocytes; Female; Gene Deletion; Genes, Reporter; Hemeproteins; Hemoglobins; Malaria; Male; Mice; Mice, Inbred BALB C; Mutation; Plasmodium berghei; Reticulocytes | 2015 |
Artesunate. The standard intravenous treatment for severe attacks of malaria.
Topics: Administration, Intravenous; Antimalarials; Artemisinins; Artesunate; Humans; Malaria; Quinine; Severity of Illness Index | 2014 |
Synergistic effect of aqueous extract of Telfaria occidentalis on the biological activities of artesunate in Plasmodium berghei infected mice.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Cucurbita; Drug Combinations; Drug Synergism; Malaria; Mice; Phytotherapy; Plant Extracts; Plant Leaves; Plants, Medicinal; Plasmodium berghei | 2014 |
Intravenous Artesunate Reduces Parasite Clearance Time, Duration of Intensive Care, and Hospital Treatment in Patients With Severe Malaria in Europe: The TropNet Severe Malaria Study.
Topics: Administration, Intravenous; Adult; Antimalarials; Artemisinins; Artesunate; Europe; Female; Humans; Malaria; Male; Quinine; Retrospective Studies; Time Factors; Treatment Outcome | 2015 |
Intravenous Artesunate for the Treatment of Severe and Complicated Malaria in the United States: Clinical Use Under an Investigational New Drug Protocol.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Drug Therapy, Combination; Drugs, Investigational; Female; Humans; Infant; Injections, Intravenous; Malaria; Male; Medication Adherence; Middle Aged; Parasitemia; Retrospective Studies; Treatment Outcome; United States; Young Adult | 2015 |
Early and severe haemolysis after treatment with artesunate for severe malaria.
Topics: Adult; Anemia, Hemolytic; Antimalarials; Artemisinins; Artesunate; Female; Hemolysis; Humans; Malaria | 2015 |
Therapeutic efficacy of artesunate-amodiaquine and artemether-lumefantrine combinations in the treatment of uncomplicated malaria in two ecological zones in Ghana.
Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Drug Combinations; Ecology; Female; Ghana; Humans; Infant; Malaria; Male; Plasmodium falciparum; Prospective Studies | 2016 |
Feasibility and acceptability of injectable artesunate for the treatment of severe malaria in the Democratic Republic of Congo.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Child; Democratic Republic of the Congo; Female; Humans; Injections, Intravenous; Malaria; Male; Treatment Outcome; Young Adult | 2016 |
UK malaria treatment guidelines 2016.
Topics: Adult; Antimalarials; Artemisinins; Artesunate; Breast Feeding; Child; Child, Preschool; Female; Humans; Malaria; Malaria, Falciparum; Malaria, Vivax; Plasmodium falciparum; Plasmodium vivax; Pregnancy; Pregnancy Complications, Parasitic; Primaquine; Travel | 2016 |
Lopinavir/ritonavir enhanced the antimalarial activity of amodiaquine and artesunate in a mouse model of Plasmodium berghei.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Artesunate; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; HIV Protease Inhibitors; Lopinavir; Malaria; Mice; Plasmodium berghei; Ritonavir | 2016 |
Inhibition of Glutathione Biosynthesis Sensitizes Plasmodium berghei to Antifolates.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Female; Glutamate-Cysteine Ligase; Glutathione; Malaria; Mice; Mice, Inbred BALB C; Plasmodium berghei; Pyrimethamine; Sulfadoxine | 2016 |
Feasibility, acceptability and impact of integrating malaria rapid diagnostic tests and pre-referral rectal artesunate into the integrated community case management programme. A pilot study in Mchinji district, Malawi.
Topics: Administration, Rectal; Adult; Antimalarials; Artemisinins; Artesunate; Case Management; Child, Preschool; Chromatography, Affinity; Cross-Sectional Studies; Diagnostic Tests, Routine; Female; Humans; Infant; Malaria; Malawi; Male; Patient Acceptance of Health Care; Pilot Projects; Referral and Consultation | 2016 |
The Community As the Patient in Malaria-Endemic Areas: Preempting Drug Resistance with Multiple First-Line Therapies.
Topics: Antimalarials; Artemisinins; Artesunate; Drug Resistance, Microbial; Drug Therapy, Combination; Endemic Diseases; Health Policy; Humans; Malaria; Malaria, Falciparum; Mefloquine | 2016 |
The role of red blood cell exchange for severe imported malaria in the artesunate era: a retrospective cohort study in a referral centre.
Topics: Administration, Intravenous; Adult; Antimalarials; Artemisinins; Artesunate; Cohort Studies; Erythrocyte Transfusion; Exchange Transfusion, Whole Blood; Female; Humans; Malaria; Male; Middle Aged; Retrospective Studies; Spain | 2016 |
Transfusion-transmitted severe Plasmodium knowlesi malaria in a splenectomized patient with beta-thalassaemia major in Sabah, Malaysia: a case report.
Topics: Administration, Intravenous; Artemisinins; Artesunate; Female; Humans; Malaria; Malaysia; Plasmodium knowlesi; Splenectomy; Tetrahydrofolate Dehydrogenase; Transfusion Reaction; Treatment Outcome; Young Adult | 2016 |
Adherence to national guidelines for the diagnosis and management of severe malaria: a nationwide, cross-sectional survey in Malawi, 2012.
Topics: Administration, Intravenous; Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Child, Preschool; Cross-Sectional Studies; Disease Management; Female; Guideline Adherence; Health Services Research; Humans; Malaria; Malawi; Male; Quinine; Young Adult | 2016 |
Artesunate-mefloquine: a malaria treatment for African children?
Topics: Antimalarials; Artemisinins; Artesunate; Child; Drug Therapy, Combination; Humans; Malaria; Malaria, Falciparum; Mefloquine; Treatment Outcome | 2016 |
Adherence to malaria diagnosis and treatment guidelines among healthcare workers in Ogun State, Nigeria.
Topics: Adult; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Case Management; Cross-Sectional Studies; Delivery of Health Care; Diagnostic Tests, Routine; Drug Prescriptions; Drug Therapy, Combination; Female; Guideline Adherence; Health Facilities; Health Personnel; Humans; Malaria; Male; Middle Aged; Nigeria; Practice Guidelines as Topic; Private Sector; Public Sector; Young Adult | 2016 |
Comparative pharmacokinetics and pharmacodynamics of intravenous artelinate versus artesunate in uncomplicated Plasmodium coatneyi-infected rhesus monkey model.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Disease Models, Animal; Macaca mulatta; Malaria; Splenectomy; Treatment Outcome; United States | 2016 |
Intravascular haemolysis with haemoglobinuria in a splenectomized patient with severe Plasmodium knowlesi malaria.
Topics: Artemisinins; Artesunate; Hemoglobinuria; Hemolysis; Humans; Malaria; Malaysia; Male; Middle Aged; Plasmodium knowlesi; Splenectomy | 2016 |
Health worker perspectives on the possible use of intramuscular artesunate for the treatment of severe malaria at lower-level health facilities in settings with poor access to referral facilities in Nigeria: a qualitative study.
Topics: Adult; Antimalarials; Artemisinins; Artesunate; Attitude of Health Personnel; Case Management; Female; Health Facilities; Health Personnel; Humans; Injections, Intramuscular; Interviews as Topic; Malaria; Male; Middle Aged; Nigeria; Primary Health Care; Qualitative Research; Referral and Consultation | 2016 |
Health worker and policy-maker perspectives on use of intramuscular artesunate for pre-referral and definitive treatment of severe malaria at health posts in Ethiopia.
Topics: Administrative Personnel; Adult; Antimalarials; Artemether; Artemisinins; Artesunate; Ethiopia; Female; Health Personnel; Humans; Injections, Intramuscular; Interviews as Topic; Malaria; Male; Quinine; Young Adult | 2016 |
Feasibility of Malaria Diagnosis and Management in Burkina Faso, Nigeria, and Uganda: A Community-Based Observational Study.
Topics: Administration, Oral; Antimalarials; Artemisinins; Artesunate; Burkina Faso; Child; Child, Preschool; Community Health Workers; Diagnostic Tests, Routine; Female; Humans; Infant; Malaria; Malaria, Falciparum; Male; Nigeria; Proteins; Referral and Consultation; Uganda | 2016 |
Impact of Improving Community-Based Access to Malaria Diagnosis and Treatment on Household Costs.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Burkina Faso; Child, Preschool; Community Health Workers; Family Characteristics; Female; Health Services Accessibility; Humans; Malaria; Male; Middle Aged; Nigeria; Surveys and Questionnaires; Uganda; Young Adult | 2016 |
Training Community Health Workers to Manage Uncomplicated and Severe Malaria: Experience From 3 Rural Malaria-Endemic Areas in Sub-Saharan Africa.
Topics: Administration, Rectal; Adult; Africa South of the Sahara; Antimalarials; Artemisinins; Artesunate; Burkina Faso; Community Health Workers; Female; Humans; Malaria; Male; Middle Aged; Nigeria; Rural Population; Uganda | 2016 |
Compliance With Malaria Rapid Diagnostic Testing by Community Health Workers in 3 Malaria-Endemic Countries of Sub-Saharan Africa: An Observational Study.
Topics: Administration, Rectal; Antimalarials; Artemisinins; Artesunate; Community Health Workers; Diagnostic Tests, Routine; Female; Humans; Malaria; Male; Patient Compliance | 2016 |
Assessing Acceptability of a Diagnostic and Malaria Treatment Package Delivered by Community Health Workers in Malaria-Endemic Settings of Burkina Faso, Nigeria, and Uganda.
Topics: Antimalarials; Artemisinins; Artesunate; Burkina Faso; Community Health Workers; Diagnostic Tests, Routine; Female; Humans; Malaria; Male; Nigeria; Uganda | 2016 |
Severe Malaria in African Children - The Need for Continuing Investment.
Topics: Africa South of the Sahara; Antimalarials; Artemisinins; Artesunate; Child; Clinical Trials as Topic; Fluid Therapy; Humans; Malaria | 2016 |
The dangers of accepting a single diagnosis: case report of concurrent Plasmodium knowlesi malaria and dengue infection.
Topics: Antimalarials; Artemisinins; Artesunate; Coinfection; Dengue; Dengue Virus; Doxycycline; Humans; Malaria; Malaysia; Male; Middle Aged; Plasmodium knowlesi; Thailand; Treatment Outcome | 2017 |
Impact of Extended Duration of Artesunate Treatment on Parasitological Outcome in a Cytocidal Murine Malaria Model.
Topics: Amodiaquine; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Disease Models, Animal; Female; Malaria; Mice; Mice, Inbred BALB C; Quinolines | 2017 |
Adverse effects of mefloquine for the treatment of uncomplicated malaria in Thailand: A pooled analysis of 19, 850 individual patients.
Topics: Adolescent; Adult; Anorexia; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Dizziness; Dose-Response Relationship, Drug; Drug Combinations; Drug Therapy, Combination; Female; Host-Parasite Interactions; Humans; Malaria; Male; Mefloquine; Nausea; Outcome Assessment, Health Care; Plasmodium falciparum; Plasmodium vivax; Psychotic Disorders; Pyrimethamine; Sulfadoxine; Thailand; Vomiting; Young Adult | 2017 |
Pharmacokinetic and pharmacodynamic evaluation of intramuscular artesunate in healthy beagle dogs.
Topics: Animals; Antimalarials; Area Under Curve; Artemisinins; Artesunate; Creatine Kinase; Dogs; Dose-Response Relationship, Drug; Drug Tolerance; Injections, Intramuscular; Malaria; Muscle, Skeletal | 2008 |
Artesunate for malaria.
Topics: Antimalarials; Artemisinins; Artesunate; Humans; Malaria; Sesquiterpenes; Time Factors; United States | 2008 |
Artesunate for malaria.
Topics: Absorption; Animals; Antimalarials; Artemisinins; Artesunate; Humans; Injections, Intramuscular; Malaria; Sesquiterpenes | 2008 |
Artesunate for malaria.
Topics: Antimalarials; Artemisinins; Artesunate; Developing Countries; Fraud; Humans; Malaria; Sesquiterpenes | 2008 |
Detecting counterfeit antimalarial tablets by near-infrared spectroscopy.
Topics: Antimalarials; Artemisinins; Artesunate; Calibration; Chromatography, High Pressure Liquid; Confidence Intervals; Drug Contamination; Drug Packaging; Fraud; Humans; Malaria; Reproducibility of Results; Spectroscopy, Near-Infrared; Tablets; Time Factors | 2008 |
Synthesis, antimalarial activity, and intracellular targets of MEFAS, a new hybrid compound derived from mefloquine and artesunate.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Cell Line; Dose-Response Relationship, Drug; Humans; Magnetic Resonance Spectroscopy; Malaria; Malaria, Falciparum; Mefloquine; Mice; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum | 2008 |
[Two cases of fulminant hepatitis during a curative treatment with an artesunate-amodiaquine combination].
Topics: Adult; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Chemical and Drug Induced Liver Injury; Fatal Outcome; Female; Humans; Malaria | 2009 |
Efficacy of monotherapies and artesunate-based combination therapies in children with uncomplicated malaria in Somalia.
Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Humans; Infant; Malaria; Male; Pyrimethamine; Somalia; Sulfadoxine; Treatment Outcome | 2009 |
Pre-referral rectal artesunate in severe malaria.
Topics: Administration, Rectal; Adult; Africa; Antimalarials; Artemisinins; Artesunate; Child, Preschool; Community Health Services; Health Services Accessibility; Humans; Malaria; Rural Health Services | 2009 |
Does artesunate prolong the electrocardiograph QT interval in patients with severe malaria?
Topics: Adult; Antimalarials; Artemisinins; Artesunate; Blood Pressure; Electrocardiography; Ethanolamines; Fluorenes; Glasgow Coma Scale; Heart Rate; Humans; Long QT Syndrome; Lumefantrine; Malaria; Male; Patient Selection | 2009 |
Plasmodium berghei: efficacy of 5-fluoroorotate in combination with commonly used antimalarial drugs in a mouse model.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Dapsone; Drug Synergism; Drug Therapy, Combination; Malaria; Male; Mice; Mice, Inbred ICR; Orotic Acid; Parasitemia; Plasmodium berghei; Pyrimethamine | 2009 |
Malaria - change in therapeutic policy.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Combinations; Drug Resistance; Humans; Malaria; Pyrimethamine; Sulfadoxine; Treatment Outcome | 2009 |
Advances in global biotechnology and local resources to treat malaria.
Topics: Antimalarials; Artemether; Artemisia; Artemisinins; Artesunate; Drug Approval; Drug Resistance, Multiple; Drugs, Investigational; Global Health; Humans; Malaria; Minnesota; Phytotherapy | 2009 |
Pre-referral artesunate in severe malaria.
Topics: Administration, Rectal; Antimalarials; Artemisinins; Artesunate; Humans; Malaria; Patient Selection; Placebos; Randomized Controlled Trials as Topic; Referral and Consultation; Research Design | 2009 |
Drug resistance and in vitro susceptibility of Plasmodium falciparum in Thailand during 1988-2003.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Humans; Malaria; Mefloquine; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinine; Thailand | 2009 |
Factors influencing adherence to referral advice following pre-referral treatment with artesunate suppositories in children in rural Tanzania.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Caregivers; Female; Health Knowledge, Attitudes, Practice; Humans; Malaria; Male; Medication Adherence; Middle Aged; Referral and Consultation; Rural Health; Suppositories; Young Adult | 2009 |
A stratified random survey of the proportion of poor quality oral artesunate sold at medicine outlets in the Lao PDR - implications for therapeutic failure and drug resistance.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chemistry Techniques, Analytical; Cross-Sectional Studies; Drug Resistance; Humans; Laos; Malaria; Random Allocation; Treatment Failure | 2009 |
[Availability of antimalarial agents in Dutch hospitals].
Topics: Antimalarials; Artemisinins; Artesunate; Humans; Malaria; Malaria, Falciparum; Netherlands; Pharmacy Service, Hospital; Quinine | 2009 |
Successful introduction of artesunate combination therapy is not enough to fight malaria: results from an adherence study in Sierra Leone.
Topics: Adolescent; Adult; Aged; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Caregivers; Child; Child, Preschool; Drug Therapy, Combination; Female; Health Knowledge, Attitudes, Practice; Humans; Infant; Malaria; Male; Medication Adherence; Middle Aged; Parents; Risk Factors; Sierra Leone; Surveys and Questionnaires; Young Adult | 2010 |
The use of placebo in a trial of rectal artesunate as initial treatment for severe malaria patients en route to referral clinics: ethical issues.
Topics: Administration, Rectal; Antimalarials; Artemisinins; Artesunate; Health Services Accessibility; Humans; Malaria; Medication Adherence; Placebos; Randomized Controlled Trials as Topic; Referral and Consultation; Rural Health; Suppositories | 2010 |
Is it too soon to eliminate quinine?
Topics: Adult; Africa; Anti-Infective Agents; Antimalarials; Artemisinins; Artesunate; Child; Humans; Malaria; Quinine | 2010 |
Management of malaria and other severe infections in rural Africa and Asia.
Topics: Administration, Rectal; Antimalarials; Artemisinins; Artesunate; Bangladesh; Ghana; Humans; Malaria; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Rural Health; Tanzania | 2010 |
Dynamics of Plasmodium falciparum parasitemia regarding combined treatment regimens for acute uncomplicated malaria, Antioquia, Colombia.
Topics: Administration, Oral; Animals; Antimalarials; Artemisinins; Artesunate; Clinical Protocols; Colombia; Drug Therapy, Combination; Female; Humans; Malaria; Malaria, Falciparum; Male; Mefloquine; Parasitemia; Patient Compliance; Plasmodium falciparum; Primaquine; Treatment Outcome | 2010 |
Cervical lymphadenopathy: a rare presentation of malaria.
Topics: Adult; Artemisinins; Artesunate; Diagnosis, Differential; Doxycycline; Female; Fever; Humans; Incidental Findings; Lymphatic Diseases; Malaria; Plasmodium falciparum; Plasmodium vivax; Treatment Outcome | 2010 |
Knowledge and acceptability of the rectal treatment route in Laos and its application for pre-referral emergency malaria treatment.
Topics: Administration, Rectal; Adult; Antimalarials; Artemisinins; Artesunate; Attitude of Health Personnel; Child, Preschool; Cross-Sectional Studies; Emergency Medical Services; Female; Health Knowledge, Attitudes, Practice; Humans; Infant; Laos; Malaria; Male; Patient Acceptance of Health Care | 2010 |
Prereferral rectal artesunate for treatment of severe childhood malaria: a cost-effectiveness analysis.
Topics: Administration, Rectal; Africa; Antimalarials; Artemisinins; Artesunate; Child, Preschool; Cost-Benefit Analysis; Health Services Accessibility; Humans; Infant; Infant, Newborn; Malaria; Referral and Consultation; Rural Population; Time Factors | 2010 |
Cost-effective use of prereferral treatment for severe malaria.
Topics: Administration, Rectal; Antimalarials; Artemisinins; Artesunate; Community Networks; Cost-Benefit Analysis; Delivery of Health Care; Endemic Diseases; Health Services Accessibility; Humans; Malaria | 2010 |
Immunological consequences of intermittent preventive treatment against malaria in Senegalese preschool children.
Topics: Antibodies, Protozoan; Antimalarials; Artemisinins; Artesunate; Chemoprevention; Child, Preschool; Drug Combinations; Female; Humans; Immunoglobulin G; Infant; Malaria; Male; Placebos; Plasmodium falciparum; Pyrimethamine; Senegal; Sulfadoxine | 2010 |
Drug dispensing practices during implementation of artemisinin-based combination therapy at health facilities in rural Tanzania, 2002-2005.
Topics: Adolescent; Age Factors; Antimalarials; Artemisinins; Artesunate; Case Management; Child; Child, Preschool; Drug Combinations; Drug Costs; Drug Prescriptions; Drug Therapy, Combination; Humans; Infant; Malaria; Practice Patterns, Physicians'; Prospective Studies; Pyrimethamine; Rural Health Services; Sulfadoxine; Tanzania | 2011 |
Intermittent preventive therapy for malaria: arguments in favour of artesunate and sulphamethoxypyrazine - pyrimethamine combination.
Topics: Antimalarials; Artemisinins; Artesunate; Child; Drug Combinations; Drug Resistance, Multiple; Female; Humans; Infant; Malaria; Plasmodium; Pyrimethamine; Sulfalene | 2011 |
Artesunate for severe malaria in African children.
Topics: Africa; Antimalarials; Artemisinins; Artesunate; Bacteremia; Child; Child, Preschool; Humans; Malaria; Parasitemia; Severity of Illness Index | 2011 |
Use artesunate not quinine to treat severe malaria, say experts.
Topics: Antimalarials; Artemisinins; Artesunate; Drug Substitution; Humans; Malaria; Quinine | 2011 |
Artesunate for severe malaria.
Topics: Adult; Antimalarials; Artemisinins; Artesunate; Child; Drug Costs; Humans; Malaria; Quinine | 2011 |
In vitro and in vivo assessment of the anti-malarial activity of Caesalpinia pluviosa.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Brazil; Caesalpinia; Cell Line; Cell Survival; Disease Models, Animal; Drug Synergism; Humans; Malaria; Mice; Mice, Inbred C57BL; Plant Bark; Plant Extracts; Plants, Medicinal; Plasmodium chabaudi; Plasmodium falciparum; Quercetin; Rodent Diseases | 2011 |
The antiplasmodial activity of Anogeissus leiocarpus and its effect on oxidative stress and lipid profile in mice infected with Plasmodium bergheii.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Blood Chemical Analysis; Combretaceae; Disease Models, Animal; Lipids; Liver; Malaria; Mice; Oxidative Stress; Parasitemia; Plant Bark; Plant Extracts; Plasmodium berghei; Superoxide Dismutase; Treatment Outcome | 2012 |
Responding to the evidence for the management of severe malaria.
Topics: Antimalarials; Artemisinins; Artesunate; Critical Illness; Evidence-Based Practice; Health Care Costs; Health Knowledge, Attitudes, Practice; Humans; Information Dissemination; Malaria; Practice Guidelines as Topic; Quinine; Training Support; World Health Organization | 2011 |
Cost-effectiveness of parenteral artesunate for treating children with severe malaria in sub-Saharan Africa.
Topics: Africa South of the Sahara; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Cost-Benefit Analysis; Health Care Costs; Humans; Infusions, Parenteral; Malaria; Outcome Assessment, Health Care; Severity of Illness Index | 2011 |
Severe Plasmodium knowlesi malaria in a tertiary care hospital, Sabah, Malaysia.
Topics: Acute Kidney Injury; Adult; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Ethanolamines; Female; Fluorenes; Hospitals, Urban; Humans; Lumefantrine; Malaria; Malaysia; Microscopy; Middle Aged; Parasitemia; Patient Selection; Plasmodium knowlesi; Polymerase Chain Reaction; Quinine; Respiratory Distress Syndrome; Severity of Illness Index; Shock; Survival Rate | 2011 |
From quinine to artesunate in Africa.
Topics: Africa; Antimalarials; Artemisinins; Artesunate; Humans; Malaria; Quinine; World Health Organization | 2011 |
Parenteral artesunate access programme aims at reducing malaria fatality rates in South Africa.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Artesunate; Female; Health Services Accessibility; Humans; Infusions, Parenteral; Malaria; Male; Middle Aged; South Africa; Young Adult | 2011 |
Pre-referral rectal artesunate in severe malaria: flawed trial.
Topics: Administration, Rectal; Africa; Antimalarials; Artemisinins; Artesunate; Bangladesh; Bias; Checklist; Double-Blind Method; Drug Administration Schedule; Evidence-Based Medicine; Humans; Intention to Treat Analysis; Malaria; Multicenter Studies as Topic; Patient Selection; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Referral and Consultation; Reproducibility of Results; Research Design; Sample Size; Severity of Illness Index; Time Factors; Treatment Outcome; World Health Organization | 2011 |
Response to: Pre-referral rectal artesunate in severe malaria: a flawed trial.
Topics: Antimalarials; Artemisinins; Artesunate; Humans; Malaria; Randomized Controlled Trials as Topic; Referral and Consultation; Research Design | 2011 |
Treatment of imported severe malaria with artesunate instead of quinine--more evidence needed?
Topics: Antimalarials; Artemisinins; Artesunate; Humans; Injections, Intravenous; Malaria; Quinine | 2011 |
Effects of artesunate on parasite recrudescence and dormancy in the rodent malaria model Plasmodium vinckei.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Disease Models, Animal; Malaria; Mice; Plasmodium | 2011 |
Tolerability and safety of primaquine in Papua New Guinean children 1 to 10 years of age.
Topics: Aging; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Cohort Studies; Female; Glucosephosphate Dehydrogenase Deficiency; Hemoglobins; Humans; Infant; Malaria; Malaria, Falciparum; Malaria, Vivax; Male; New Guinea; Primaquine | 2012 |
[Use of intravenous artemisinin derivatives in severe malaria].
Topics: Antimalarials; Artemisinins; Artesunate; Child, Preschool; Female; Humans; Injections, Intravenous; Malaria; Male; Severity of Illness Index | 2012 |
Treatment outcome of intravenous artesunate in patients with severe malaria in the Netherlands and Belgium.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Artesunate; Belgium; Female; Humans; Infusions, Intravenous; Malaria; Male; Middle Aged; Netherlands; Retrospective Studies; Travel; Treatment Outcome; Young Adult | 2012 |
Assessing the consistency assumption by exploring treatment by covariate interactions in mixed treatment comparison meta-analysis: individual patient-level covariates versus aggregate trial-level covariates.
Topics: Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Dapsone; Drug Combinations; Ethanolamines; Fluorenes; Humans; Malaria; Meta-Analysis as Topic; Models, Statistical; Outcome Assessment, Health Care; Proguanil; Quinolines; Regression Analysis | 2012 |
Intravenous β-artemether formulation (ARM NLC) as a superior alternative to commercial artesunate formulation.
Topics: Administration, Intravenous; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Disease Models, Animal; Malaria; Male; Mice; Parasitemia; Plasmodium berghei; Treatment Outcome | 2012 |
Deaths due to Plasmodium knowlesi malaria in Sabah, Malaysia: association with reporting as Plasmodium malariae and delayed parenteral artesunate.
Topics: Adult; Aged; Antimalarials; Artemisinins; Artesunate; Bacteremia; Diagnostic Errors; Female; Gram-Negative Bacterial Infections; Humans; Malaria; Malaysia; Male; Middle Aged; Plasmodium knowlesi; Plasmodium malariae | 2012 |
A prospective comparative study of knowlesi, falciparum, and vivax malaria in Sabah, Malaysia: high proportion with severe disease from Plasmodium knowlesi and Plasmodium vivax but no mortality with early referral and artesunate therapy.
Topics: Adult; Aged; Antimalarials; Artemisinins; Artesunate; Female; Humans; Malaria; Malaria, Falciparum; Malaria, Vivax; Malaysia; Male; Middle Aged; Parasitemia; Plasmodium falciparum; Plasmodium knowlesi; Plasmodium vivax; Prospective Studies; Risk Factors; Severity of Illness Index; Time Factors; Treatment Outcome; Young Adult | 2013 |
Access to artemisinin-combination therapy (ACT) and other anti-malarials: national policy and markets in Sierra Leone.
Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Drug Costs; Geography; Health Policy; Health Services Accessibility; Humans; Malaria; Organizations, Nonprofit; Pharmacies; Poverty; Private Sector; Public Sector; Sierra Leone | 2012 |
Effect of single nucleotide polymorphisms in cytochrome P450 isoenzyme and N-acetyltransferase 2 genes on the metabolism of artemisinin-based combination therapies in malaria patients from Cambodia and Tanzania.
Topics: Alleles; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Arylamine N-Acetyltransferase; Base Sequence; Cambodia; Cytochrome P-450 Enzyme System; Drug Combinations; Ethanolamines; Fluorenes; Gene Frequency; Humans; Isoenzymes; Malaria; Mefloquine; Pharmacogenetics; Polymorphism, Single Nucleotide; Quinolines; Sequence Analysis, DNA; Tanzania | 2013 |
Published reports of delayed hemolytic anemia after treatment with artesunate for severe malaria--worldwide, 2010-2012.
Topics: Adolescent; Adult; Aged; Anemia, Hemolytic; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Female; Humans; Malaria; Male; Middle Aged; Retrospective Studies; Severity of Illness Index; Time Factors | 2013 |
[The synergistic action of guanghuoxiang volatile oil and sodium artesunate against Plasmodium berghei and reversal of SA-resistant Plasmodium berghei].
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Lamiaceae; Malaria; Mice; Oils, Volatile; Phytotherapy; Plasmodium berghei; Sesquiterpenes | 2000 |
Efficacy comparison of intravenous artelinate and artesunate in Plasmodium berghei-infected Sprague-Dawley rats.
Topics: Animals; Artemisinins; Artesunate; Disease Models, Animal; Dose-Response Relationship, Drug; Injections, Intravenous; Malaria; Male; Parasitemia; Plant Extracts; Plasmodium berghei; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Time Factors | 2003 |
Artesunate combinations for malaria.
Topics: Antimalarials; Artemisinins; Artesunate; Cost-Benefit Analysis; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Mefloquine; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Outcome | 2004 |
Ghana battles drug-resistant malaria with artesunate.
Topics: Antimalarials; Artemisinins; Artesunate; Child, Preschool; Chloroquine; Drug Resistance; Ghana; Humans; Malaria; Sesquiterpenes | 2004 |
Fluoroartemisinin: trifluoromethyl analogues of artemether and artesunate.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Drug Stability; Fluorine; Hydrolysis; Malaria; Mice; Plasmodium berghei; Plasmodium falciparum; Sesquiterpenes; Structure-Activity Relationship | 2004 |
Fake antimalarials in Southeast Asia are a major impediment to malaria control: multinational cross-sectional survey on the prevalence of fake antimalarials.
Topics: Antimalarials; Artemisinins; Artesunate; Asia, Southeastern; Cross-Sectional Studies; Drug Labeling; Fraud; Humans; Malaria; Mefloquine; Self Medication; Sesquiterpenes | 2004 |
A qualitative study to identify community structures for management of severe malaria: a basis for introducing rectal artesunate in the under five years children in Nakonde District of Zambia.
Topics: Administration, Rectal; Antimalarials; Artemisinins; Artesunate; Child, Preschool; Community Health Services; Community Health Workers; Family Characteristics; Female; Focus Groups; Health Knowledge, Attitudes, Practice; Humans; Infant; Interviews as Topic; Malaria; Male; Medically Underserved Area; Parents; Patient Acceptance of Health Care; Sesquiterpenes; Suppositories; Zambia | 2005 |
WHO combats counterfeit malaria drugs in Asia.
Topics: Antimalarials; Artemisinins; Artesunate; Asia; Drugs, Generic; Fraud; Humans; Malaria; Sesquiterpenes; World Health Organization | 2005 |
Neurotoxicity due to antimalarial therapy associated with misdiagnosis of malaria.
Topics: Adult; Antimalarials; Anxiety; Artemisinins; Artesunate; Ataxia; Chloroquine; Diagnostic Errors; Humans; Malaria; Male; Sesquiterpenes; Tremor | 2005 |
New malaria combination cheaper and easier to take.
Topics: Administration, Oral; Amodiaquine; Artemisinins; Artesunate; Drug Costs; Drug Therapy, Combination; Humans; Malaria; Sesquiterpenes | 2005 |
The chemotherapy of rodent malaria. LXIII. Drug combinations to impede the selection of drug resistance, part 6: the potential value of chlorproguanil and dapsone in combination, and with the addition of artesunate.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Dapsone; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Malaria; Male; Mice; Parasitemia; Plasmodium berghei; Plasmodium chabaudi; Plasmodium yoelii; Proguanil; Rodent Diseases; Sesquiterpenes | 2005 |
Factors contributing to the development of anaemia in Plasmodium falciparum malaria: what about drug-resistant parasites?
Topics: Amodiaquine; Anemia; Animals; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Resistance; Drug Therapy, Combination; Humans; Infant; Malaria; Plasmodium falciparum; Sesquiterpenes | 2006 |
Ex vivo perfusion of human spleens maintains clearing and processing functions.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Erythrocytes; Humans; In Vitro Techniques; Malaria; Perfusion; Phagocytosis; Plasmodium falciparum; Sesquiterpenes; Spleen | 2006 |
Improving the availability of artesunate for treatment of severe malaria.
Topics: Adult; Antimalarials; Artemisinins; Artesunate; Australia; Child; Drug Approval; Humans; Malaria; Sesquiterpenes | 2006 |
New potential antimalarial agents: therapeutic-index evaluation of pyrroloquinazolinediamine and its prodrugs in a rat model of severe malaria.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Malaria; Maximum Tolerated Dose; Parasitemia; Plasmodium berghei; Prodrugs; Pyrroles; Quinazolines; Random Allocation; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Therapeutic Equivalency | 2006 |
Manslaughter by fake artesunate in Asia--will Africa be next?
Topics: Adult; Africa; Antimalarials; Artemisinins; Artesunate; Asia; Drug and Narcotic Control; Drug Contamination; Drug Costs; Drug Packaging; Fraud; Global Health; Humans; Malaria; Male; Sesquiterpenes; Travel | 2006 |
Intravenous artesunate recommended for patients with severe malaria: position statement from TropNetEurop.
Topics: Antimalarials; Artemisinins; Artesunate; Communicable Diseases, Emerging; Europe; Humans; Incidence; Injections, Intravenous; Malaria; Population Surveillance; Practice Guidelines as Topic; Sesquiterpenes; Severity of Illness Index; Treatment Outcome | 2005 |
Role of traditional healers in the management of severe malaria among children below five years of age: the case of Kilosa and Handeni Districts, Tanzania.
Topics: Adult; Aged; Antimalarials; Artemisinins; Artesunate; Child, Preschool; Female; Focus Groups; Health Knowledge, Attitudes, Practice; Humans; Interviews as Topic; Malaria; Male; Medicine, African Traditional; Patient Acceptance of Health Care; Referral and Consultation; Rural Health; Sesquiterpenes; Severity of Illness Index; Tanzania | 2006 |
Toxicity evaluation of artesunate and artelinate in Plasmodium berghei-infected and uninfected rats.
Topics: Acute Kidney Injury; Animals; Antimalarials; Artemisinins; Artesunate; Brain Diseases; Dose-Response Relationship, Drug; Lethal Dose 50; Malaria; Male; Necrosis; Plasmodium berghei; Random Allocation; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Tail; Vascular Diseases | 2007 |
Malaria. "One step forward, two steps back".
Topics: Animals; Antimalarials; Artemisinins; Artesunate; DNA, Bacterial; Drug Therapy, Combination; Humans; Malaria; Mefloquine; Plasmodium malariae; Sesquiterpenes | 2006 |
Characterization of counterfeit artesunate antimalarial tablets from southeast Asia.
Topics: Antimalarials; Artemisinins; Artesunate; Asia, Southeastern; Drug Labeling; Erythromycin; Humans; Malaria; Sesquiterpenes; Tablets | 2006 |
Population pharmacokinetics of artesunate and dihydroartemisinin following intra-rectal dosing of artesunate in malaria patients.
Topics: Administration, Rectal; Adolescent; Adult; Africa; Aging; Antimalarials; Artemisinins; Artesunate; Asia, Southeastern; Child; Child, Preschool; Demography; Female; Humans; Infant; Malaria; Male; Middle Aged; Parasitemia; Salvage Therapy; Sesquiterpenes; Sex Factors; Suppositories; Treatment Outcome | 2006 |
Recognition, perceptions and treatment practices for severe malaria in rural Tanzania: implications for accessing rectal artesunate as a pre-referral.
Topics: Administration, Rectal; Adolescent; Adult; Aged; Antimalarials; Artemisinins; Artesunate; Child; Decision Making; Female; Humans; Interviews as Topic; Malaria; Medicine, African Traditional; Middle Aged; Pregnancy; Referral and Consultation; Tanzania; Young Adult | 2007 |
Case 32-2006: a girl with fever after a visit to Africa.
Topics: Antimalarials; Artemisinins; Artesunate; Child, Preschool; Exchange Transfusion, Whole Blood; Female; Humans; Malaria; Quinidine; Sesquiterpenes | 2007 |
Plasmodium yoelii: influence of antimalarial treatment on acquisition of immunity in BALB/c and DBA/2 mice.
Topics: Animals; Antibodies, Protozoan; Antimalarials; Artemisinins; Artesunate; Chloroquine; Female; Immunoglobulin G; Interferon-gamma; Malaria; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Parasitemia; Plasmodium yoelii; Recurrence; Sesquiterpenes | 2007 |
UK recommendations for severe malaria are worrying.
Topics: Antimalarials; Artemisinins; Artesunate; Drug Industry; Humans; Malaria; Sesquiterpenes | 2007 |
Counterfeit artemisinin derivatives and Africa: update from authors.
Topics: Africa; Antimalarials; Artemisinins; Artesunate; Asia; Drug and Narcotic Control; Drug Contamination; Drug Costs; Drug Packaging; Fraud; Humans; Malaria; Sesquiterpenes; Travel | 2007 |
Plasmodium vivax cerebral malaria.
Topics: Animals; Artemisinins; Artesunate; Central Nervous System Protozoal Infections; Child; Humans; Malaria; Malaria, Cerebral; Male; Plasmodium vivax; Sesquiterpenes | 2007 |
Community coverage of an antimalarial combination of artesunate and amodiaquine in Makamba Province, Burundi, nine months after its introduction.
Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Burundi; Child, Preschool; Community Health Services; Cross-Sectional Studies; Drug Therapy, Combination; Fever; Humans; Infant; Infant, Newborn; Malaria; Sesquiterpenes | 2007 |
Battling the malaria iceberg with chloroquine in India.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Delivery of Health Care; Drug Combinations; Drug Resistance; Humans; India; Malaria; Preventive Health Services; Pyrimethamine; Sesquiterpenes; Socioeconomic Factors; Sulfadoxine; Time Factors | 2007 |
[ASAQ, a breakthrough in the fight against malaria].
Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Drug Combinations; Drug Industry; Humans; International Cooperation; Malaria; Sesquiterpenes | 2007 |
Malaria pharmacovigilance in Africa: lessons from a pilot project in Mpumalanga Province, South Africa.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Female; Humans; Infant; Malaria; Male; Middle Aged; Pilot Projects; Product Surveillance, Postmarketing; Pyrimethamine; Sesquiterpenes; South Africa; Sulfadoxine | 2007 |
Pharmacologic advances in the global control and treatment of malaria: combination therapy and resistance.
Topics: Amodiaquine; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Dapsone; Drug Design; Drug Resistance; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Global Health; Half-Life; Humans; Lumefantrine; Malaria; Mefloquine; Pregnancy; Pregnancy Complications, Infectious; Proguanil; Pyrimethamine; Quinine; Sesquiterpenes; Sulfadoxine | 2007 |
Clinical symptoms, treatment and outcome of highlands malaria in Eldoret (2420 m a.s.l.) and comparison to malaria in hyper-immune population in endemic region of Southern Sudan.
Topics: Altitude; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Drug Therapy, Combination; Endemic Diseases; Greenhouse Effect; Humans; Kenya; Malaria; Prognosis; Sesquiterpenes; Sudan; Treatment Outcome | 2007 |
Chorea in a 29-year-old Nigerian following antimalarial treatment with artesunate.
Topics: Adult; Antimalarials; Artemisinins; Artesunate; Chorea; Diazepam; Humans; Malaria; Male; Muscle Relaxants, Central; Nigeria; Treatment Outcome | 2008 |
A collaborative epidemiological investigation into the criminal fake artesunate trade in South East Asia.
Topics: Artemisia; Artemisinins; Artesunate; Asia, Southeastern; Drug Contamination; Fraud; Humans; Internationality; Malaria; Sesquiterpenes | 2008 |
Anti-malarial efficacy of pyronaridine and artesunate in combination in vitro and in vivo.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Drug Resistance, Multiple; Drug Therapy, Combination; In Vitro Techniques; Inhibitory Concentration 50; Malaria; Mice; Naphthyridines; Plasmodium; Plasmodium berghei; Plasmodium falciparum; Sesquiterpenes; Treatment Outcome | 2008 |
Disease and drug interactions: treating malaria with artesunate plus amodiaquine in patients also receiving treatment for concomitant HIV infection.
Topics: Amodiaquine; Anti-HIV Agents; Antimalarials; Artemisinins; Artesunate; Drug Interactions; Drug Therapy, Combination; HIV Infections; Humans; Malaria; Neutropenia; Sesquiterpenes | 2008 |
IV artesunate for severe malaria.
Topics: Antimalarials; Artemisinins; Artesunate; Humans; Infusions, Intravenous; Malaria; Sesquiterpenes | 2008 |
Clinical studies on treatment of cerebral malaria with qinghaosu and its derivatives.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Brain Diseases; Child; Child, Preschool; Female; Humans; Malaria; Male; Middle Aged; Plasmodium falciparum; Sesquiterpenes | 1982 |
The antimalarial and toxic effect of artesunate on animal models.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Dogs; Female; Guinea Pigs; Macaca mulatta; Malaria; Male; Mice; Plasmodium; Plasmodium berghei; Rabbits; Sesquiterpenes | 1982 |
Artemisinin: current status.
Topics: Antimalarials; Antiprotozoal Agents; Artemisinins; Artesunate; Drugs, Chinese Herbal; Humans; Malaria; Sesquiterpenes | 1994 |
Comparison of in vivo and in vitro antimalarial activity of artemisinin, dihydroartemisinin and sodium artesunate in the Plasmodium berghei-rodent model.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Malaria; Mice; Plasmodium berghei; Rats; Rats, Wistar; Sesquiterpenes | 1994 |
The iron environment in heme and heme-antimalarial complexes of pharmacological interest.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Heme; Hemeproteins; Hemin; Humans; Iron; Malaria; Quinine; Sesquiterpenes; Spectroscopy, Mossbauer | 1996 |
Effects of artesunate on immune function in mice.
Topics: Adjuvants, Immunologic; Animals; Antimalarials; Artemisinins; Artesunate; Complement C3; Female; Hemolysin Proteins; Immunoglobulin G; Lymphocyte Activation; Malaria; Male; Mice; Mice, Inbred ICR; Phagocytosis; Plasmodium berghei; Sesquiterpenes | 1995 |
The chemotherapy of rodent malaria. LIII. 'Fenozan B07' (Fenozan-50F), a difluorinated 3,3'-spirocyclopentane 1,2,4-trioxane: comparison with some compounds of the artemisinin series.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Drug Synergism; Malaria; Male; Mice; Parasitemia; Peroxides; Plasmodium; Plasmodium berghei; Plasmodium yoelii; Sesquiterpenes; Spiro Compounds | 1997 |
Plasma levels of the interleukin-6 cytokine family in persons with severe Plasmodium falciparum malaria.
Topics: Acute Kidney Injury; Adolescent; Adult; Animals; Antimalarials; Artemisinins; Artesunate; Biomarkers; Ciliary Neurotrophic Factor; Female; Humans; Interleukin-6; Malaria; Malaria, Cerebral; Malaria, Falciparum; Male; Middle Aged; Nerve Growth Factors; Nerve Tissue Proteins; Plasmodium falciparum; Receptors, Interleukin-6; Reference Values; Sesquiterpenes | 1999 |
What are the World Health Organization's strategies for meeting regulatory requirements? A case study of artesunate.
Topics: Administration, Rectal; Antimalarials; Artemisinins; Artesunate; Chemistry, Pharmaceutical; Drug Approval; Europe; Evidence-Based Medicine; Health Services Needs and Demand; Humans; Malaria; Public Health; Registries; Sesquiterpenes; Time Factors; United States; World Health Organization | 1998 |
Imported malaria: successful treatment of 31 patients in the era of chloroquine resistance.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Child; Chloroquine; Drug Resistance; Female; Humans; Malaria; Male; Middle Aged; Primaquine; Quinine; Retrospective Studies; Sesquiterpenes; Travel | 1999 |
The chemotherapy of rodent malaria. LVI. Studies on the development of resistance to natural and synthetic endoperoxides.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Drug Resistance; Malaria; Male; Mice; Peroxides; Plasmodium berghei; Plasmodium yoelii; Sesquiterpenes | 1999 |
Schizontocidal effects of oral artesunate on Plasmodium berghei in mice and P knowlesi in monkeys.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Erythrocytes; Female; Macaca mulatta; Malaria; Male; Mice; Plasmodium berghei; Plasmodium knowlesi; Sesquiterpenes | 1999 |
Fake antimalaria drugs in Cambodia.
Topics: Antimalarials; Artemisinins; Artesunate; Cambodia; Humans; Malaria; Mefloquine; Product Surveillance, Postmarketing; Sesquiterpenes | 2001 |
Potent antimalarial activities of polyether antibiotic, X-206.
Topics: Actinomycetales; Animals; Anti-Bacterial Agents; Antimalarials; Artemether; Artemisinins; Artesunate; Cell Death; Cell Line; Chloroquine; Drug Resistance; Embryo, Mammalian; Embryo, Nonmammalian; Ethers, Cyclic; Humans; Malaria; Mice; Molecular Structure; Plasmodium berghei; Plasmodium falciparum; Pyrimethamine; Quinine; Sesquiterpenes | 2001 |
Histopathological changes of Macaca mulatta infected with Plasmodium knowlesi.
Topics: Animals; Artemisinins; Artesunate; Macaca mulatta; Malaria; Monkey Diseases; Plasmodium knowlesi; Quinolines; Sesquiterpenes; Suppositories | 2001 |
Mathematical modelling of malaria chemotherapy: combining artesunate and mefloquine.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Computer Simulation; Drug Therapy, Combination; Humans; Malaria; Mefloquine; Models, Biological; Parasitemia; Plasmodium; Sesquiterpenes | 2002 |
Impact of large-scale rectal artesunate deployment in the emergency management of malaria.
Topics: Administration, Rectal; Antimalarials; Artemisinins; Artesunate; Clinical Trials as Topic; Emergency Treatment; Female; Humans; International Cooperation; Malaria; Male; Patient Selection; Sesquiterpenes; Severity of Illness Index; World Health Organization | 2002 |
[Effect of artesunate transdermal preparation on Plasmodium cynomolgi].
Topics: Administration, Cutaneous; Animals; Antimalarials; Artemisinins; Artesunate; Azepines; Drug Synergism; Macaca mulatta; Malaria; Male; Plasmodium; Sesquiterpenes | 1990 |
Decreased sensitivity of artesunate and chloroquine of Plasmodium falciparum infecting hemoglobin H and/or hemoglobin constant spring erythrocytes.
Topics: Animals; Artemisinins; Artesunate; Chloroquine; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Erythrocytes; Hemoglobin H; Hemoglobins, Abnormal; Humans; Malaria; Plasmodium falciparum; Sesquiterpenes | 1989 |
[Clinical observations on 100 cases of malignant malaria treated with artesunate tablets].
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Humans; Malaria; Plasmodium falciparum; Sesquiterpenes; Tablets | 1989 |
Experimental studies on the antimalarial activity estimation by artesunate and artemether preparations per skin absorption.
Topics: Administration, Cutaneous; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Female; Malaria; Male; Mice; Plasmodium berghei; Sesquiterpenes; Skin Absorption | 1988 |
[Clinical study on the treatment of malaria with artemether and artesunate].
Topics: Adolescent; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Child; Child, Preschool; Humans; Malaria; Plasmodium falciparum; Plasmodium vivax; Pyrans; Recurrence; Sesquiterpenes | 1988 |
[Development of a qinghaosu-resistant line of Plasmodium berghei ANKA and N strain].
Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Drug Resistance, Microbial; Malaria; Male; Mice; Plasmodium berghei; Primaquine; Pyrans; Sesquiterpenes | 1986 |
The chemotherapy of rodent malaria, XL. The action of artemisinin and related sesquiterpenes.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Drug Resistance; Malaria; Male; Mice; Pigments, Biological; Plasmodium berghei; Pyrans; Sesquiterpenes | 1986 |
Antimalarial agents. III. Mechanism of action of artesunate against Plasmodium berghei infection.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Malaria; Male; Mice; Mice, Inbred Strains; Plasmodium berghei; Sesquiterpenes | 1987 |
Experimental studies on the effect of artesunate sustained released tablet on Plasmodium cynomolgi.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Delayed-Action Preparations; Female; Macaca mulatta; Malaria; Male; Sesquiterpenes; Tablets | 1987 |
[Development of a piperaquine-resistant line of Plasmodium berghei K 173 strain].
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Malaria; Male; Mefloquine; Mice; Plasmodium berghei; Quinolines; Sesquiterpenes | 1985 |