Page last updated: 2024-08-26

artesunic acid and Infections, Plasmodium

artesunic acid has been researched along with Infections, Plasmodium in 377 studies

Research

Studies (377)

TimeframeStudies, this research(%)All Research%
pre-199013 (3.45)18.7374
1990's15 (3.98)18.2507
2000's92 (24.40)29.6817
2010's165 (43.77)24.3611
2020's92 (24.40)2.80

Authors

AuthorsStudies
Anstey, NM; Barber, BE; Cooper, DJ; Grigg, MJ; Rajahram, GS; van Schalkwyk, DA; William, T1
Boechat, N; Campos Aguiar, AC; da Silva Araújo, M; Krettli, AU; Medeiros, JF; Penna-Coutinho, J; Pereira, DB; Rios, CT; Sá, PM1
Barton, M; Brooks, HM; Forgie, EME; Hawkes, MT1
Achia, TN; Amboko, B; Chesang, J; Kipruto, H; Machini, B; Mwaniki, P1
Abohelwa, M; Agusala, V; Gharamti, A; Hassan, M1
Amboko, B; Bejon, P; Githuka, G; Machini, B; Snow, RW; Zurovac, D1
Guo, Q; Lin, L; Shi, Z; Tang, Z; Xiong, H1
Bartoloni, A; Bianchi, L; Botta, A; Castelli, F; Chechi, F; Comelli, A; Galli, L; Giulia, G; Spinicci, M; Tomasoni, LR; Vellere, I; Zammarchi, L1
Baraka, V; Kamugisha, E; Kapesa, A; Kidenya, B; Konje, E; Marwa, K; Mukonzo, J; Swedberg, G1
Bottieau, E; Huits, R; Rosanas-Urgell, A; Van den Bossche, D; Van Ierssel, S1
Creek, DJ; Dogovski, C; Du, Y; Giannangelo, C; He, W; Li, X; Shami, GJ; Tilley, L; Yang, T; Zhou, W1
Behera, PK; Nair, AA; Tripathy, KP1
Asinya, M; Jeuronlon, MK; Kamara, P; Koko, VS; Kollie, A; Ma, L; Menard, D; Nyansaiye, P; Parwon, S; Pratt, OJ; Ringwald, P; Taweh, F; Tehmeh, L; Vonhm, B; Warsame, M1
Oraebosi, MI1
Basco, LK; Briolant, S; Casimiro, PN; Kobawila, SC; Matondo Diassivi, B; Ndounga, M; Pembet Singana, B; Ringwald, P; Youndouka, JM1
Grundmann, O; Hernandez Maldonado, J1
Akano, B; Angiro, I; Athieno, P; Awor, P; Ayodeji, K; Brunner, NC; Buj, V; Burri, C; Cereghetti, N; Delvento, G; Hetzel, MW; Kalenga, JC; Kimera, J; Lambiris, MJ; Lee, TT; Lengeler, C; Napier, HG; Okitawutshu, J; Okon, C; Omoluabi, E; Ross, A; Signorell, A; Tshefu Kitoto, A; Tumukunde, G; Visser, T; Yusuf, O1
Arbe-Barnes, S; Borghini-Fuhrer, I; Dimessa Mbadinga, LB; Duparc, S; Egger-Adam, D; Groger, M; Kahunu Mesia, G; Miller, R; Mombo-Ngoma, G; Muena Mujobu, TB; Ntamabyaliro, NY; Ramharter, M; Shin, J; Tona Lutete, G; Zoleko Manego, R1
Bivona, DA; Bonacci, P; Marino, A1
Jochum, J; Kurth, F; Mischlinger, J; Ramharter, M1
Bruschi, F; Fabiani, S; L'Episcopia, M; Mangano, V; Motta, V; Severini, C; Sparavelli, R; Verdenelli, S1
Baguiya, A; Barry, N; Hien, D; Kaboré, JMT; Siribié, M; Sirima, SB; Soulama, I; Tchouatieu, AM; Tiono, AB1
Dondorp, AM; Fanello, C; Onyamboko, M; Peto, TJ; Warsame, M; Watson, JA; White, N1
Baiden, R; Binka, F; Compaore, A; Diande, NA; Hien, FS; Rouamba, T; Sondo, P; Tahita, MC; Tinto, H; Traore-Coulibaly, M; Valea, I; Yerbanga, IW1
Daily, JP; Khan, N; Minuti, A1
Bamadio, A; Chico, RM; Cohee, LM; Coumare, S; Dara, A; Diarra, M; Djimde, AA; Doumbo, OK; Kodio, A; Maiga, H; Opondo, C; Sagara, I; Sidibe, B; Tekete, M; Traore, OB; Traore, ZI1
Lucchi, NW; Mace, KE; Tan, KR1
Abanyie, F; Ng, J; Tan, KR1
Choi, G; Choy, JH; Kim, JY; Lee, SE; Piao, H; Rejinold, NS; Shin, HI1
Alpern, JD; Stauffer, WM; Thomas, CM1
Rathjen, NA; Shahbodaghi, SD1
Brunner, N; Buj, V; Burri, C; Delvento, G; Hetzel, M; Kalenga, JC; Lee, T; Lengeler, C; Luketa, S; Mukomena, E; Mwaluke, F; Okitawutshu, J; Sangare, M; Signorell, A; Tshefu, A1
White, NJ2
Akano, BK; Angiro, I; Athieno, P; Awor, P; Ayodeji, K; Brunner, NC; Buj, V; Burri, C; Cereghetti, N; Cohen, JM; Delvento, G; Hetzel, MW; Kalenga, JC; Kimera, J; Kwiatkowski, M; Lambiris, MJ; Lee, TT; Lengeler, C; Napier, HG; Okitawutshu, J; Okon, C; Omoluabi, E; Signorell, A; Tshefu, A; Tumukunde, G; Visser, T; Yusuf, O1
Adebayo, JO; Tijjani, H1
Adegnika, AA; Akinosho, MA; Davi, SD; Dimessa-Mbadinga, LB; Handrich, C; Kreidenweiss, A; Kremsner, PG; Lell, B; Mombo-Ngoma, G; Ndzebe-Ndoumba, WF; Nordmann, T; Okwu, DG; Ramharter, M; Stelzl, D; Veletzky, L; Zoleko-Manego, R1
Akano, B; Athieno, P; Awor, P; Ayodeji, K; Brunner, N; Burri, C; Delvento, G; Hetzel, MW; Kalenga, JC; Kimera, J; Lee, T; Lengeler, C; Okitawutshu, J; Okon, C; Omoluabi, E; Signorell, A; Tshefu, A; Tumukunde, G; Yusuf, O1
Awor, P; Buj, V; Burri, C; Cohen, JM; Hetzel, MW; Lambiris, MJ; Lengeler, C; Omoluabi, E; Signorell, A; Tshefu, A; Visser, T1
von Seidlein, L1
Accrombessi, M; Cook, J1
Awor, P; Balogun, V; Brunner, NC; Buj, V; Burri, C; Cereghetti, N; Delvento, G; Emedo, E; Galactionova, K; Hetzel, MW; Kagwire, F; Lambiris, MJ; Lee, TT; Lengeler, C; Luketa, S; Musiitwa, M; Napier, HG; Okitawutshu, J; Olosunde, O; Omoluabi, E; Sangare, M; Signorell, A; Ssempala, R; Tshefu, A; Venga, GN; Visser, T1
Dondorp, AM; Peto, TJ; Watson, JA; White, NJ1
Mace, KE; Schultz, JS; Tan, KR1
Chandelia, S; Gangwal, M; Patharia, N1
Akano, BK; Angiro, I; Athieno, P; Awor, P; Ayodeji, K; Brunner, NC; Buj, V; Burri, C; Cereghetti, N; Delvento, G; Hetzel, MW; Kalenga, JC; Kimera, J; Lambiris, MJ; Lee, TT; Lengeler, C; Napier, HG; Okitawutshu, J; Okon, C; Okuma, J; Omoluabi, E; Signorell, A; Tshefu, A; Tumukunde, G; Visser, T; Yusuf, O1
Moffitt, CA; O'Brien, N; Olupot-Olupot, P; Onen, JW1
Babigumira, K; Lugand, MM; Muniina, P; Nsona, H; Oliff, MS; Phuka, J; Rietveld, H; Sande, J1
Liu, Z; Ma, Z; Sun, CB1
Awor, P; Buj, V; Burri, C; Cohen, JM; Hetzel, MW; Kwiatkowski, M; Lambiris, MJ; Lengeler, C; Okitawutshu, J; Omoluabi, E; Signorell, A; Tshefu, A; Visser, T1
Peto, TJ; Watson, JA; White, NJ2
Bertault-Peres, P; Bonsergent, M; Flet, L; Honoré, S; Lepelletier, A; Perez, T; Tching-Sin, M1
Barber, C; Chanda, E; Green, C; Kureya, T; Moyo, B; Mpande, B; Mubuyaeta, K; Mudenda, M; Mundia, L; Nyirenda, R; Piringondo, A; Quigley, P; Rietveld, H; Simpasa, S; Simuyuni, D; Zinumwe, G1
Alexander, K; Anstey, NM; Buffet, PA; Candrawati, F; Kambuaya, NN; Kenangalem, E; Kho, S; Leonardo, L; Margayani, DS; Poespoprodjo, JR; Prayoga, P; Rini, H; Shanti, PAI; Yayang, BTG1
Hasan, N; Hore, R; Kressler, J; Mäder, K1
Li, Y; Qiu, M; Rong, R; Su, J; Xu, E; Yuan, W; Zhang, S1
Baraka, V; Francis, F; Geertruyden, JV; Gesase, S; Kyaruzi, E; Lusingu, JPA; Madebe, R; Makenga, G; Minja, DTR; Mtove, G; Nakato, S1
Dini, S; Fanello, C; Fitzpatrick, P; Haghiri, A; Price, DJ; Rajasekhar, M; Simpson, JA; Tarning, J; Watson, J; White, NJ1
Chellan, P; Harding, CR; Kaschula, CH; Munnik, BL1
Angeli, A; Capasso, C; Carradori, S; Carta, F; D'Agostino, I; De Luca, V; Kocken, CHM; Supuran, CT; Zara, S; Zeeman, AM1
Arama, C; Beavogui, AH; Dicko, A; Djimde, A; Djimde, M; Fofana, B; Kayentao, K; Mens, PF; Ouedraogo, JB; Sagara, I; Schallig, HD; Sirima, SB; Tshiongo, JK1
Burri, C; Delvento, G; Hetzel, MW; Kalenga, JC; Lengeler, C; Okitawutshu, J; Signorell, A; Tshefu, A1
Campagnucci, N; Chediack, V; Cunto, E; Gregori Sabelli, R; Lamberto, Y; Saul, P1
Angoulvant, A; Bouchaud, O; Buffet, P; Caumes, E; Chamillard, X; Houzé, S; Izri, A; Jauréguiberry, S; Kendjo, E; Magne, D; Matheron, S; Ndour, AP; Paccoud, O; Surgers, L; Thellier, M; Vinatier, I; Wyplosz, B1
Bienvenu, AL; Bonnot, G; Kouakou, YI; Lavoignat, A; Leboucher, G; Picot, S; Tod, M1
Lefèvre, A; Léonard, P1
Addo, MM; Adegnika, AA; Agbenyega, T; Ansong, D; Cramer, JP; Fürst, S; Jacobs, T; Kremsner, PG; Kurth, F; May, J; Ramharter, M; Rolling, T; Scheu, K; Sylverken, J; Vinnemeier, CD1
Barber, C; Chanda, E; Chizema, E; Green, C; Hugo, P; Kureya, T; Moonga, H; Mpande, B; Mubuyaeta, K; Quigley, P; Simfukwe, V; Simuyuni, D; van der Weije, K1
Conroy, AL; Elphinstone, RE; Hawkes, MT; Hume, HA; Kain, KC; Namasopo, S; Opoka, RO1
Faye, O; Musau, J; Mvumbi, PM; Okitolonda, E; Situakibanza, H1
Ahmad, RA; Kenangalem, E; Laksono, IS; Lampah, DA; Murhandarwati, EEH; Poespoprodjo, JR; Sikora, SA; Sugiarto, P1
Anvikar, AR; Das, MK; Mitra, JK; Savargaonkar, D; Srivastava, B; Valecha, N; Verma, A; Yadav, CP1
Petersen, E; Picot, S1
Ariey, F; Chy, S; Dorina Bustos, M; Eam, R; Izac, B; Kauy, C; Ke, S; Khim, N; Kim, S; Kloeung, N; Leang, R; Mairet-Khedim, M; Marmai, C; Mey Bouth, D; Ringwald, P; Witkowski, B1
Acácio, S; Aide, P; Alonso, PL; Bambo, G; Bassat, Q; Camprubí, D; Macete, E; Madrid, L; Mayor, A; Menéndez, C; Muñoz, J; Quintó, L; Sitoe, A; Valente, AM; Varo, R; Vitorino, P1
Essiben, F; Mayane, DN; Meka, E; Nkwabong, E1
Bianchi, L; Bortone, B; Chiappini, E; Galli, L; Montagnani, C; Tersigni, C; Venturini, E; Zammarchi, L1
Abbas, FB; Ali, AS; Ali, AW; Barnes, R; Björkman, A; Frumento, P; Mårtensson, A; Morris, U; Msellem, M; Soe, A1
Achia, TNO; Amboko, B; Kipruto, H; Machini, B; Malla, L; Snow, RW; Zurovac, D1
Chandramohan, D; Clark, TD; Dorsey, G; Havlir, DV; Jagannathan, P; Kajubi, R; Kakuru, A; Kamya, MR; Nakalembe, M; Ochieng, T; Ochokoru, H; Ruel, T; Staedke, SG1
Aschenbrenner, DS1
Baker, L; Barnes, KI; Blaylock, M; Blumberg, L; Frean, J; Misiani, E; Raman, J; Ukpe, IS1
Al Khaja, KAJ; Sequeira, RP1
Angoulvant, A; Argy, N; Bouchaud, O; Bruneel, F; Buffet, P; Caumes, E; Chambrion, C; Courtin, D; Danis, M; Delacour, H; Gay, F; Henry, B; Houzé, S; Jauréguiberry, S; Kendjo, E; Larréché, S; Lebrun-Vignes, B; Mouri, O; Ndour, PA; Piarroux, R; Roussel, C; Siriez, JY; Taieb, A; Thellier, M1
Ball, L; Bensman, TJ; Chilukuri, DM; Colangelo, PM; Earp, JC; Kitabi, E; O'Shaughnessy, E; Reynolds, KS; Smith, H; Yasinskaya, Y1
Arwati, H; Basuki, DR; Ekasari, W; Wahyuni, TS1
Cao, P; Dini, S; Dondorp, A; Fowkes, FJI; Kremsner, P; Krishna, S; Maude, RJ; McCaw, JM; Price, RN; Simpson, JA; Tarning, J; White, MT; White, NJ; Whyte, JM; Zaloumis, SG1
Hughes, E; Jagannathan, P; Mohamed Ali, A; Savic, RM; Wallender, E1
Achan, J; Arbe-Barnes, S; Borghini-Fuhrer, I; Conteh, B; D'Alessandro, U; Dabira, ED; Duparc, S; Hachizovu, S; Lawal, B; Manyando, C; Mendy, A; Miller, R; Mulenga, JM; Mwanza, S; Ndiath, MO; Nyang, H; Shin, J1
Bancone, G; Carrara, VI; Chu, C; Duanguppama, J; Gilder, ME; Haohankhunnatham, W; Imwong, M; Konghahong, K; Lee, SJ; McGready, R; Min, AM; Nosten, F; Paw, MK; Phyo, AP; Pimanpanarak, M; Proux, S; Saito, M; Singhasivanon, P; Tun, NW; Turner, C; Viladpai-Nguen, J; White, NJ1
Agnandji, ST; Allen, SJ; Arbe-Barnes, S; Assi, SB; Bigoga, JD; Borghini-Fuhrer, I; Duparc, S; Groger, M; Koukouikila-Koussounda, F; Kremsner, PG; Miller, R; Mombo-Ngoma, G; Ntamabyaliro, NY; Ntoumi, F; Ramharter, M; Shin, J; Tona Lutete, G1
Adah, D; Chen, X; Hu, W; Qin, L1
Chai, L; Guo, W; Li, N; Li, Y; Ren, G; Wang, R; Wang, X; Yang, L; Yang, Q; Yi, B; Zhang, G; Zhang, S1
Abanyie, F; Acharya, SD; Bowe, M; Leavy, I; Tan, KR1
Balogun, AA; Olanlokun, JO; Olorunsogo, OO1
Asuzu, OV; Ezeigbo, II; Nwaehujor, CO; Nwibo, DD; Nwobi, OC1
Buffet, PA; Caumes, E; Jauréguiberry, S; Ndour, PA; Roussel, C; Thellier, M1
Buyze, J; D'Alessandro, U; Hachizovu, S; Kabuya, JB; Kasongo, W; Mulenga, J; Mulenga, M; Mwakazanga, D; Nambozi, M; Van Geertruyden, JP1
Chang, ZW; Claser, C; Rénia, L; Russell, B1
Argy, N; Biligui, S; Bonnefoy, S; Buffet, PA; Chartrel, N; Danis, M; Dondorp, AM; Gay, F; Ghose, A; Hassan, MMU; Hossain, MA; Houzé, S; Jauréguiberry, S; Kendjo, E; Kingston, HWF; Langui, D; Larréché, S; Mérens, A; Mouri, O; Ndour, PA; Perillaud, C; Plewes, K; Roussel, C; Thellier, M; Woodrow, CJ1
Barboza, TMT; Chaves, GC; Gonçalves, LPB; Luiza, VL; Stobbaerts, EG1
Bagire, PG; Daddy, NB; Kalisya, LM; Towler, MJ; Watt, RL; Weathers, PJ1
Akter, J; Aogo, RA; Best, SE; Cromer, D; Davenport, MP; Elliott, T; Engel, JA; Gartlan, KH; Haque, A; James, KR; Khoury, DS; Sebina, I; Soon, MSF; Thomas, BS1
Amin, P; Baker, T; Karnad, DR; Nor, MBM; Richards, GA1
Kumar, RS; Puttappa, N; Yamjala, K1
Falade, MO; Komoni, F; Nwuba, RI1
Achan, J; Byakika-Kibwika, P; Karera-Gonahasa, C; Kiragga, AN; Kiwanuka, N; Lamorde, M; Mayanja-Kizza, H; Merry, C; Nsobya, S; Talisuna, AO1
Du, Y; Ismail, M; Li, X; Ling, L; Yao, C1
Crawley, J; Dondorp, A; Keene, CM; Mukaka, M; Ohuma, EO1
Amin, P; Karnad, DR; Richards, GA; Silva, GS1
Alexander, ND; Chandramohan, D; Clarke, SE; Hansen, KS; Lal, S; Magnussen, P; Ndyomugenyi, R; Paintain, L1
Anstey, NM; Barber, BE; Chandna, A; Drakeley, CJ; Grigg, MJ; Menon, J; Patel, K; Piera, K; Rajahram, GS; Schimann, E; Wilkes, CS; William, T; Yeo, TW1
Helinski, MEH; Muhangi, D; Nuwa, A; Okui, AP; Strachan, CE; Tibenderana, JK1
Akter, J; Aogo, RA; Cromer, D; Davenport, MP; Elliott, T; Fogg, LG; Haque, A; Khoury, DS; Laohamonthonkul, P; Liligeto, UN; Nair, AS; Pernold, CPS; Romanczuk, AS; Soon, MSF; Thomas, BS1
Dias, S; Donegan, S; Welton, NJ1
Du, Y; Ismail, M; Li, X; Ling, L1
Almuedo, A; Bassat, Q; Camprubí, D; Casals-Pascual, C; Malvy, D; Muñoz, J; Pereira, A; Rodriguez-Valero, N; Varo, R1
Jauréguiberry, S1
Garrido Jareño, M; Otero Reigada, MDC; Peman García, J; Ramírez Cuentas, JH; Roselló Guijarro, M; Urtasun Erburu, A1
Alcalá-Minagorre, PJ; Rabaneda-Gutiérrez, L; Sánchez-Bautista, A1
Arbe-Barnes, S; Borghini-Fuhrer, I; Craft, CJ; Duparc, S; Fleckenstein, L; Miller, RM; Shin, CS1
Ashley, E; Boel, M; Carrara, VI; Chu, C; Lwin, KM; McGready, R; Nosten, F; Phyo, AP; Proux, S; Rijken, M; Singhasivanon, P; Sriprawat, K; White, N; Wiladphaingern, J1
Bagai, U; Rajan, A1
Efferth, T; Eichhorn, T; Schneider, D; Veerappan, A; Zeino, M1
Goto, T; Kameta, K; Kaneshima, H; Nakao, T; Shirono, N; Yamane, T; Yoshida, T1
Bunts, L; Casper, C; Dorsey, G; Gantt, S; Huang, ML; Magaret, A; Rosenthal, PJ; Selke, S; Wald, A1
Burchard, GD; Cramer, JP; Kluge, S; Rolling, T; Schmiedel, S; Wichmann, D1
Dondorp, AM; Faiz, MA; Hien, TT; Mokuolu, OA; Pukrittayakamee, S; White, NJ1
de Vries, PJ; Kreeftmeijer-Vegter, AR; van Veldhuizen, CK1
Agbaje, EO; Aina, OO; Iribhogbe, OI; Oreagba, IA; Ota, AD1
Bathurst, I; Brun, R; Burrows, JN; Charman, SA; Fantauzzi, P; Ihara, M; Itoh, I; Lotharius, J; Morizzi, J; Scheurer, C; Schleiferböck, S; Shackleford, DM; White, KL; Wittlin, S1
Clark, RL1
Adegnika, AA; Agbenyega, T; Ansong, D; Burchard, GD; Cramer, JP; Issifou, S; Kremsner, PG; Krishna, S; Löhr, SJ; May, J; Mordmüller, B; Rolling, T; Spahlinger, D; Sylverken, J1
Burchard, GD1
Adedeji, WA; Adewole, IF; Akinola, IT; Akinyinka, OO; Aweeka, FT; Darin, KM; Fehintola, FA; Lindegardh, N; Ma, Q; Morse, GD; Murphy, RL; Ojengbede, O; Parikh, S; Scarsi, KK; Taiwo, B; Tarning, J1
Attama, AA; Chime, SA; Chinaeke, EE; Okore, VC; Onyishi, VI1
Amah, DJ; Bello, UM; Gbodi, AT; Kabiru, AY; Makun, HA; Ogbadoyi, EO1
Anvikar, AR; Das, MK; Gupta, R; Mishra, N; Rana, R; Shahi, B; Singh, S; Valecha, N1
Ashley, EA; Gomes, M; Libaud-Moal, A; Millet, P; Olliaro, P; Rodrigues, A; Vermeersch, A; White, NJ1
Aguiar, AC; Amaral, NS; De Marco, L; Krettli, AU; Pereira, DB1
Kumar, KK; Prasad, DM; Rajyalakshmi, M; Satish, PV; Sowjanya, M; Sunita, K1
Kameda, K1
Huijben, S; Jones, MJ; Pollitt, LC; Read, AF; Salathé, RM; Sim, DG1
Eisenhut, M; Okebe, J1
Adegbolagun, OM; Emikpe, BO; Ogunremi, Y; Woranola, IO2
Das, MK; Savargaonkar, D; Shah, N; Srivastava, B; Valecha, N1
Chen, L; Choi, K; Gibson, C; Huang, F; Keitany, GJ; Peng, X; Vignali, M; Wang, R1
Attama, AA; Chime, SA; Chinaeke, EE; Müller-Goymann, CC; Ogbonna, JD; Okore, VC1
Anstey, NM; Barber, BE; Dhanaraj, P; Grigg, MJ; Menon, J; Price, RN; Rajahram, G; von Seidlein, L; William, T; Yeo, TW1
Boonloed, A; Dunfield, EM; Koesdjojo, MT; Remcho, VT; Wu, Y1
Green, MD; Herrington, J; Newton, PN; Phonlavong, C; Ranieri, N; Sampson, E; Satzger, RD; Tabernero, P; Thao, K; Verbois, L; Witkowski, MR1
Berman, J; Im-Erbsin, R; Li, Q; Obaldia, N; Ohrt, C; Xie, L1
Corsello, MA; Garg, NK1
Boggild, AK; Graham, C; Kain, KC; Keystone, JS; Krajden, S; Lee, J; Pavenski, K1
Jongwutiwes, S; Kobasa, T; Nakaviroj, S; Putaporntip, C; Teeranaipong, P1
Claeys, Y; D'Alessandro, U; De Crop, M; Halidou, T; Kalanda, G; Menten, J; Mulenga, M; Mutabingwa, T; Mwakazanga, D; Mwapasa, V; Nambozi, M; Phiri, LK; Ravinetto, R; Schurmans, C; Tagbor, H; Thriemer, K; Traore, M; Valea, I; Van Geertruyden, JP1
Blomberg, B; Heggheim, Å; Mørch, K1
Day, NP; Hanpithakpon, W; Hlaing, N; Kloprogge, F; McGready, R; Nosten, F; Phyo, AP; Rijken, MJ; Tarning, J; Than, HH; White, NJ; Zin, NT1
Adedeji, ON; Ademowo, OG; Bolaji, OO; Falade, CO; Osonuga, OA1
Ader, F; Angoulvant, A; Bricaire, F; Buffet, P; Caumes, E; Danis, M; Houzé, S; Jauréguiberry, S; Kendjo, E; Lebrun-Vignes, B; Matheron, S; Mayaux, J; Mazier, D; Ndour, PA; Pistone, T; Rapp, C; Roussel, C; Sonneville, R; Thellier, M; Wyplosz, B1
Aime, E; Annoura, T; Arese, P; Capuccini, B; Chevalley-Maurel, S; Crisanti, A; Deroost, K; Franke-Fayard, BM; Janse, CJ; Khan, SM; Koster, AJ; Kroeze, H; Langhorne, J; Lin, JW; Mommaas-Kienhuis, AM; O'Toole, T; Prins, F; Ramesar, J; Ravelli, RB; Sajid, M; Schwarzer, E; Spaccapelo, R; Tanke, HJ; Van den Steen, PE1
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Ambroise-Thomas, P1
Rozendaal, J1
Ishiyama, A; Kohana, A; Manabe, C; Omura, S; Otoguro, K; Shiomi, K; Ui, H; Yamada, H1
Chen, L; Li, G; Lu, Y; Luo, Z1
Ginsburg, H; Hoshen, MB; Stein, WD1
Li, AY; Liu, X; Xie, PS; Xuan, WY; Zhao, Y1
Bunyaratvej, A; Butthep, P; Fucharoen, S; Yuthavong, Y1
Guo, XB1
Cai, Y; Li, AY; Xie, PS; Xuan, WY; Zhao, Y1
Feng, TG; Guo, XB; Li, GQ; Li, PS; Shi, WZ; Wang, HF; Zhang, SF1
Du, YL; Jiang, Q; Li, CS1
Li, ZL; Peters, W; Robinson, BL; Warhurst, DC1
Hall, IH; Lee, KH; Oswald, CB; Yokoi, T; Zhao, Y1
Gu, WG; Hou, HM; Jia, MH; Lei, TK; Li, AY; Liu, X; Xie, PS; Zhao, Y1
Li, GD1

Reviews

43 review(s) available for artesunic acid and Infections, Plasmodium

ArticleYear
Clinical management of Plasmodium knowlesi malaria.
    Advances in parasitology, 2021, Volume: 113

    Topics: Antimalarials; Artesunate; Humans; Malaria; Malaria, Falciparum; Plasmodium knowlesi

2021
Pediatric Malaria: Global and North American Perspectives.
    Pediatric clinics of North America, 2022, Volume: 69, Issue:1

    Topics: Acute Kidney Injury; Anemia; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Child; Child, Preschool; Female; Global Health; Humans; Infant; Malaria; Male; North America; Plasmodium; Respiratory Distress Syndrome; Travel

2022
New Insights into Artesunate as a Pleiotropic Regulator of Innate and Adaptive Immune Cells.
    Journal of immunology research, 2022, Volume: 2022

    Topics: Adaptive Immunity; Animals; Antimalarials; Artemisinins; Artesunate; Humans; Immune System Diseases; Immunity, Innate; Immunomodulation; Malaria

2022
Therapeutic efficacy of artemether-lumefantrine, artesunate-amodiaquine and dihydroartemisinin-piperaquine in the treatment of uncomplicated Plasmodium falciparum malaria in Sub-Saharan Africa: A systematic review and meta-analysis.
    PloS one, 2022, Volume: 17, Issue:3

    Topics: Africa South of the Sahara; Amodiaquine; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Drug Combinations; Ethanolamines; Humans; Malaria; Malaria, Falciparum; Piperazines; Plasmodium falciparum; Quinolines

2022
Drug-Drug Interactions of Artemisinin-Based Combination Therapies in Malaria Treatment: A Narrative Review of the Literature.
    Journal of clinical pharmacology, 2022, Volume: 62, Issue:10

    Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Humans; Malaria; Malaria, Falciparum

2022
Updates in central nervous system malaria: literature review and considerations.
    Current opinion in infectious diseases, 2022, 06-01, Volume: 35, Issue:3

    Topics: Adult; Antimalarials; Artesunate; Central Nervous System; Child; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum

2022
Diagnosis, Treatment, and Prevention of Malaria in the US: A Review.
    JAMA, 2022, 08-02, Volume: 328, Issue:5

    Topics: Adult; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Humans; Malaria; Malaria, Falciparum; Travel; Travel-Related Illness; United States

2022
Severe malaria.
    Malaria journal, 2022, Oct-06, Volume: 21, Issue:1

    Topics: Africa South of the Sahara; Anti-Bacterial Agents; Antimalarials; Artesunate; Child; Humans; Malaria

2022
Pre-referral rectal artesunate: no cure for unhealthy systems.
    The Lancet. Infectious diseases, 2023, Volume: 23, Issue:6

    Topics: Antimalarials; Artemisinins; Artesunate; Child; Humans; Malaria; Observational Studies as Topic; Randomized Controlled Trials as Topic; Referral and Consultation

2023
The wrongful indictment of pre-referral rectal artesunate further delays the roll-out of this lifesaving drug.
    The Lancet. Infectious diseases, 2023, Volume: 23, Issue:6

    Topics: Administration, Rectal; Antimalarials; Artemisinins; Artesunate; Humans; Malaria; Observational Studies as Topic; Pharmaceutical Preparations; Referral and Consultation

2023
Systematic review of artesunate pharmacokinetics: Implication for treatment of resistant malaria.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2019, Volume: 89

    Topics: Administration, Intravenous; Administration, Oral; Antimalarials; Artemisinins; Artesunate; Asia, Southeastern; Drug Monitoring; Drug Resistance; Humans; Malaria; Malaria, Falciparum

2019
IV artesunate for severe malaria.
    The Medical letter on drugs and therapeutics, 2020, 08-10, Volume: 62, Issue:1604

    Topics: Administration, Intravenous; Animals; Antimalarials; Artesunate; Clinical Trials as Topic; Humans; Malaria; Severity of Illness Index

2020
Drug treatment and prevention of malaria in pregnancy: a critical review of the guidelines.
    Malaria journal, 2021, Jan-23, Volume: 20, Issue:1

    Topics: Adult; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artesunate; Chloroquine; Drug Combinations; Female; Humans; Malaria; Parasitemia; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Quinine; Sulfadoxine

2021
Malaria PK/PD and the Role Pharmacometrics Can Play in the Global Health Arena: Malaria Treatment Regimens for Vulnerable Populations.
    Clinical pharmacology and therapeutics, 2021, Volume: 110, Issue:4

    Topics: Amodiaquine; Anti-HIV Agents; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Child, Preschool; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Female; Global Health; HIV Infections; Humans; Malaria; Malnutrition; Mefloquine; Models, Biological; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Quinolines; Sulfadoxine; Vulnerable Populations

2021
The mechanisms of action of Plasmodium infection against cancer.
    Cell communication and signaling : CCS, 2021, 07-09, Volume: 19, Issue:1

    Topics: Animals; Artesunate; Cell Proliferation; Humans; Immune Checkpoint Inhibitors; Immunotherapy; Malaria; Mice; Neoplasms; Tumor Microenvironment

2021
Artesunate to treat severe malaria in travellers: review of efficacy and safety and practical implications.
    Journal of travel medicine, 2017, Mar-01, Volume: 24, Issue:2

    Topics: Antimalarials; Artemisinins; Artesunate; Humans; Malaria; Retrospective Studies; Travel

2017
Intensive care in severe malaria: Report from the task force on tropical diseases by the World Federation of Societies of Intensive and Critical Care Medicine.
    Journal of critical care, 2018, Volume: 43

    Topics: Acute Kidney Injury; Adult; Advisory Committees; Antimalarials; Artemisinins; Artesunate; Child; Critical Care; Female; Humans; Malaria; Male; Respiratory Distress Syndrome; Severity of Illness Index; Societies, Medical; Tropical Medicine

2018
[Severe and complicated malaria].
    La Revue du praticien, 2019, Volume: 69, Issue:2

    Topics: Adult; Anemia, Hemolytic; Antimalarials; Artesunate; Child; Female; France; Humans; Malaria; Malaria, Falciparum; Pregnancy; Severity of Illness Index

2019
Malaria.
    Lancet (London, England), 2014, Feb-22, Volume: 383, Issue:9918

    Topics: Africa South of the Sahara; Amodiaquine; Animals; Anopheles; Antimalarials; Artemisinins; Artesunate; Asia, Southeastern; Chloroquine; Drug Administration Schedule; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Humans; Insecticide-Treated Bednets; Insecticides; Malaria; Malaria Vaccines; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Pregnancy; Pregnancy Complications, Infectious; Primary Prevention; Pyrimethamine; Quinine; Quinolines; Seasons; Sulfadoxine

2014
Pre-referral rectal artesunate for severe malaria.
    The Cochrane database of systematic reviews, 2014, May-29, Issue:5

    Topics: Administration, Rectal; Adult; Age Factors; Antimalarials; Artemisinins; Artesunate; Bangladesh; Child; Child, Preschool; Emergency Medical Services; Ghana; Humans; Infant; Malaria; Rural Health; Tanzania

2014
Synthetic chemistry fuels interdisciplinary approaches to the production of artemisinin.
    Natural product reports, 2015, Volume: 32, Issue:3

    Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Drug Resistance, Microbial; Malaria; Molecular Structure; Plasmodium falciparum

2015
Post-artesunate delayed haemolysis ‒ report of four cases and review of the literature.
    Swiss medical weekly, 2015, Volume: 145

    Topics: Adult; Anemia, Hemolytic; Antimalarials; Artemisinins; Artesunate; Erythrocytes; Female; Hemolysis; Humans; Malaria; Male

2015
Treatment regimens for pregnant women with falciparum malaria.
    Expert review of anti-infective therapy, 2016, Volume: 14, Issue:8

    Topics: Antimalarials; Artemisinins; Artesunate; Drug Administration Schedule; Female; Humans; Injections, Intravenous; Malaria; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications, Parasitic; Pregnancy Trimesters; Severity of Illness Index; World Health Organization

2016
The Treatment of Plasmodium knowlesi Malaria.
    Trends in parasitology, 2017, Volume: 33, Issue:3

    Topics: Antimalarials; Artemisinins; Artesunate; Asia, Southeastern; Chloroquine; Coinfection; Humans; Malaria; Malaria, Falciparum; Plasmodium knowlesi

2017
Artemisinin-based combination therapy for treating uncomplicated malaria.
    The Cochrane database of systematic reviews, 2009, Jul-08, Issue:3

    Topics: Antimalarials; Artemisinins; Artesunate; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Parasitemia; Pyrimethamine; Quinolines; Randomized Controlled Trials as Topic; Sulfadoxine

2009
Toxicity of the antimalarial artemisinin and its dervatives.
    Critical reviews in toxicology, 2010, Volume: 40, Issue:5

    Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Clinical Trials as Topic; Developing Countries; Dogs; Drug Administration Routes; Drug-Related Side Effects and Adverse Reactions; Humans; Malaria; Rabbits; Rats; Sesquiterpenes

2010
Artesunate versus quinine for treating severe malaria.
    The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3

    Topics: Adult; Antimalarials; Artemisinins; Artesunate; Child; Humans; Injections, Intramuscular; Injections, Intravenous; Malaria; Quinine; Randomized Controlled Trials as Topic

2011
Severe malaria: artesunate is now the standard treatment.
    Prescrire international, 2011, Volume: 20, Issue:120

    Topics: Adolescent; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Evidence-Based Medicine; Humans; Malaria; Severity of Illness Index

2011
Artesunate versus quinine for treating severe malaria.
    The Cochrane database of systematic reviews, 2012, Jun-13, Issue:6

    Topics: Adult; Antimalarials; Artemisinins; Artesunate; Child; Humans; Injections, Intramuscular; Injections, Intravenous; Malaria; Quinine; Randomized Controlled Trials as Topic

2012
Adjunctive management of malaria.
    Current opinion in infectious diseases, 2012, Volume: 25, Issue:5

    Topics: Antimalarials; Artemisinins; Artesunate; Blood Transfusion; Fluid Therapy; Humans; Malaria; Malaria, Cerebral; Nitric Oxide

2012
Estimating the needs for artesunate-based combination therapy for malaria case-management in Africa.
    Trends in parasitology, 2003, Volume: 19, Issue:8

    Topics: Adolescent; Adult; Africa; Age Factors; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Drug Costs; Drug Therapy, Combination; Humans; Infant; Malaria; Risk Factors; Sesquiterpenes

2003
Antimalarial compounds: from bench to bedside.
    The Journal of experimental biology, 2003, Volume: 206, Issue:Pt 21

    Topics: Age Factors; Animals; Antimalarials; Artemisinins; Artesunate; Clinical Trials as Topic; Drug Combinations; Drug Design; Drug Resistance; Malaria; Plasmodium; Sesquiterpenes

2003
New antimalarial drugs.
    Angewandte Chemie (International ed. in English), 2003, Nov-10, Volume: 42, Issue:43

    Topics: Aminoquinolines; Animals; Antimalarials; Artemisinins; Artesunate; Atovaquone; Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Design; Drug Resistance; Ethanolamines; Flavonoids; Fluorenes; Fosfomycin; Global Health; Humans; Lumefantrine; Malaria; Naphthoquinones; Naphthyridines; Plasmodium falciparum; Proguanil; Sesquiterpenes

2003
[Combined antimalarial therapy using artemisinin].
    Parassitologia, 2004, Volume: 46, Issue:1-2

    Topics: Amodiaquine; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Doxycycline; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Mefloquine; Plasmodium; Pyrimethamine; Quinine; Sesquiterpenes; Sulfadoxine

2004
Resisting resistance: dealing with the irrepressible problem of malaria.
    British journal of clinical pharmacology, 2006, Volume: 61, Issue:6

    Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Dapsone; Drug Combinations; Drug Resistance; Humans; Malaria; Proguanil; Sesquiterpenes

2006
Malaria: severe, life threatening.
    Clinical evidence, 2006, Issue:15

    Topics: Acute Disease; Antimalarials; Artemether; Artemisinins; Artesunate; Humans; Malaria; Quinine; Sesquiterpenes

2006
Rectal administration of artemisinin derivatives for the treatment of malaria.
    JAMA, 2007, Jun-06, Volume: 297, Issue:21

    Topics: Administration, Rectal; Area Under Curve; Artemether; Artemisinins; Artesunate; Humans; Malaria; Sesquiterpenes

2007
Artesunate versus quinine for treating severe malaria.
    The Cochrane database of systematic reviews, 2007, Oct-17, Issue:4

    Topics: Adult; Antimalarials; Artemisinins; Artesunate; Child; Humans; Injections, Intramuscular; Injections, Intravenous; Malaria; Quinine; Randomized Controlled Trials as Topic; Sesquiterpenes

2007
Assessment of the relative advantage of various artesunate-based combination therapies by a multi-treatment Bayesian random-effects meta-analysis.
    The American journal of tropical medicine and hygiene, 2007, Volume: 77, Issue:6

    Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Bayes Theorem; Chloroquine; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Malaria; Mefloquine; Pyrimethamine; Randomized Controlled Trials as Topic; Sesquiterpenes; Sulfadoxine; Treatment Outcome

2007
Intrarectal artemisinin derivatives.
    Medecine tropicale : revue du Corps de sante colonial, 1998, Volume: 58, Issue:3 Suppl

    Topics: Absorption; Administration, Rectal; Adult; Antimalarials; Artemether; Artemisinins; Artesunate; Child; Humans; Malaria; Metabolic Clearance Rate; Sesquiterpenes; Suppositories

1998
What role can public health institutions play in drug development for the poor? A case study of artesunate.
    Medecine tropicale : revue du Corps de sante colonial, 1998, Volume: 58, Issue:3 Suppl

    Topics: Africa; Antimalarials; Artemisinins; Artesunate; Drug and Narcotic Control; Drug Evaluation, Preclinical; Drug Industry; Endemic Diseases; Europe; Health Services Needs and Demand; Humans; International Cooperation; Malaria; Poverty; Public Health Practice; Research Support as Topic; Sesquiterpenes; United States; World Health Organization

1998
Combination therapy for malaria in Africa: hype or hope?
    Bulletin of the World Health Organization, 2000, Volume: 78, Issue:12

    Topics: Africa; Antimalarials; Artemisinins; Artesunate; Asia, Southeastern; Chloroquine; Cross-Cultural Comparison; Half-Life; Humans; Insecticide Resistance; Malaria; Mefloquine; Pyrimethamine; Self Medication; Sesquiterpenes; Sulfadoxine; Thailand

2000
[Treatment of malaria: prevention of resistance by combinations of antimalarial agents].
    Medecine tropicale : revue du Corps de sante colonial, 2000, Volume: 60, Issue:3

    Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Mefloquine; Naphthyridines; Plasmodium; Sesquiterpenes

2000

Trials

61 trial(s) available for artesunic acid and Infections, Plasmodium

ArticleYear
Effectiveness of pyronaridine-artesunate against Plasmodium malariae, Plasmodium ovale spp, and mixed-Plasmodium infections: a post-hoc analysis of the CANTAM-Pyramax trial.
    The Lancet. Microbe, 2022, Volume: 3, Issue:8

    Topics: Artesunate; Drug Combinations; Humans; Malaria; Naphthyridines; Plasmodium malariae; Plasmodium ovale

2022
Overall and Gender-Specific Effects of Intermittent Preventive Treatment of Malaria with Artemisinin-Based Combination Therapies among Schoolchildren in Mali: A Three-Group Open Label Randomized Controlled Trial.
    The American journal of tropical medicine and hygiene, 2022, 10-12, Volume: 107, Issue:4

    Topics: Amodiaquine; Anemia; Antimalarials; Artemisinins; Artesunate; Child; Drug Combinations; Drug Therapy, Combination; Female; Hemoglobins; Humans; Malaria; Malaria, Falciparum; Mali; Pyrimethamine; Sulfadoxine

2022
Effectiveness of rectal artesunate as pre-referral treatment for severe malaria in children under 5 years of age: a multi-country observational study.
    BMC medicine, 2022, 10-11, Volume: 20, Issue:1

    Topics: Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Humans; Infant, Newborn; Malaria; Referral and Consultation

2022
Effectiveness of antimalarial drug combinations in treating concomitant urogenital schistosomiasis in malaria patients in Lambaréné, Gabon: A non-randomised event-monitoring study.
    PLoS neglected tropical diseases, 2022, Volume: 16, Issue:10

    Topics: Amodiaquine; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artesunate; Drug Combinations; Ethanolamines; Gabon; Humans; Malaria; Malaria, Falciparum; Schistosomiasis haematobia

2022
Effectiveness and safety of intermittent preventive treatment with dihydroartemisinin-piperaquine or artesunate-amodiaquine for reducing malaria and related morbidities in schoolchildren in Tanzania: a randomised controlled trial.
    The Lancet. Global health, 2023, Volume: 11, Issue:8

    Topics: Amodiaquine; Antimalarials; Artesunate; Child; COVID-19; Drug Combinations; Hemoglobins; Humans; Incidence; Malaria; Malaria, Falciparum; Quinolines; Tanzania

2023
Adherence to the referral advice after introduction of rectal artesunate for pre-referral treatment of severe malaria at the community level: a noninferiority trial in the Democratic Republic of the Congo.
    Malaria journal, 2019, Dec-21, Volume: 18, Issue:1

    Topics: Administration, Rectal; Adult; Antimalarials; Artesunate; Caregivers; Child, Preschool; Democratic Republic of the Congo; Female; Humans; Infant; Infant, Newborn; Malaria; Male; Middle Aged; Mothers; Pre-Exposure Prophylaxis; Referral and Consultation; Treatment Adherence and Compliance; Young Adult

2019
Impact of intermittent preventive treatment of malaria in pregnancy with dihydroartemisinin-piperaquine versus sulfadoxine-pyrimethamine on the incidence of malaria in infancy: a randomized controlled trial.
    BMC medicine, 2020, 08-10, Volume: 18, Issue:1

    Topics: Adult; Antimalarials; Artesunate; Double-Blind Method; Drug Combinations; Female; Humans; Incidence; Infant; Infant, Newborn; Malaria; Male; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Sulfadoxine; Young Adult

2020
Efficacy, Safety and Tolerability of Pyronaridine-artesunate in Asymptomatic Malaria-infected Individuals: a Randomized Controlled Trial.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2022, 01-29, Volume: 74, Issue:2

    Topics: Antimalarials; Artesunate; Drug Combinations; Humans; Malaria; Malaria, Falciparum; Naphthyridines; Plasmodium falciparum; Treatment Outcome

2022
A randomized controlled trial of dihydroartemisinin-piperaquine, artesunate-mefloquine and extended artemether-lumefantrine treatments for malaria in pregnancy on the Thailand-Myanmar border.
    BMC medicine, 2021, 06-10, Volume: 19, Issue:1

    Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Drug Therapy, Combination; Female; Humans; Infant, Newborn; Malaria; Malaria, Falciparum; Mefloquine; Myanmar; Pregnancy; Premature Birth; Quinolines; Thailand

2021
Artemisinin-based combination therapy in pregnant women in Zambia: efficacy, safety and risk of recurrent malaria.
    Malaria journal, 2017, 05-16, Volume: 16, Issue:1

    Topics: Adolescent; Adult; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Drug Combinations; Ethanolamines; Female; Fluorenes; Humans; Malaria; Mefloquine; Pregnancy; Quinolines; Recurrence; Risk; Treatment Outcome; Young Adult; Zambia

2017
Intravenous artesunate plus Artemisnin based Combination Therapy (ACT) or intravenous quinine plus ACT for treatment of severe malaria in Ugandan children: a randomized controlled clinical trial.
    BMC infectious diseases, 2017, 12-28, Volume: 17, Issue:1

    Topics: Administration, Intravenous; Antimalarials; Artemisinins; Artesunate; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Kaplan-Meier Estimate; Malaria; Male; Quinine; Risk Factors; Treatment Outcome; Uganda

2017
A Competing-Risk Approach for Modeling Length of Stay in Severe Malaria Patients in South-East Asia and the Implications for Planning of Hospital Services.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2018, 09-14, Volume: 67, Issue:7

    Topics: Adult; Antimalarials; Artesunate; Asia, Southeastern; Female; Humans; Length of Stay; Malaria; Male; Quinine; Retrospective Studies; Young Adult

2018
Pyronaridine-artesunate or dihydroartemisinin-piperaquine versus current first-line therapies for repeated treatment of uncomplicated malaria: a randomised, multicentre, open-label, longitudinal, controlled, phase 3b/4 trial.
    Lancet (London, England), 2018, 04-07, Volume: 391, Issue:10128

    Topics: Adolescent; Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Child; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Longitudinal Studies; Malaria; Male; Naphthyridines; Quinolines; Young Adult

2018
An artesunate-containing antimalarial treatment regimen did not suppress cytomegalovirus viremia.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2013, Volume: 58, Issue:1

    Topics: Adolescent; Antimalarials; Antiviral Agents; Artemisinins; Artesunate; Child; Child, Preschool; Cytomegalovirus; Cytomegalovirus Infections; DNA, Viral; Drug Therapy, Combination; Female; Humans; Infant; Malaria; Male; Real-Time Polymerase Chain Reaction; Treatment Outcome; Uganda; Viremia

2013
Delayed hemolysis after treatment with parenteral artesunate in African children with severe malaria--a double-center prospective study.
    The Journal of infectious diseases, 2014, Jun-15, Volume: 209, Issue:12

    Topics: Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Female; Follow-Up Studies; Gabon; Ghana; Hemolysis; Humans; Infant; Malaria; Male; Prospective Studies

2014
A study protocol for a randomised open-label clinical trial of artesunate-mefloquine versus chloroquine in patients with non-severe Plasmodium knowlesi malaria in Sabah, Malaysia (ACT KNOW trial).
    BMJ open, 2014, Aug-19, Volume: 4, Issue:8

    Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Female; Humans; Malaria; Malaysia; Male; Mefloquine; Plasmodium knowlesi; Research Design; Severity of Illness Index

2014
Safe and efficacious artemisinin-based combination treatments for African pregnant women with malaria: a multicentre randomized control trial.
    Reproductive health, 2015, Jan-15, Volume: 12

    Topics: Adult; Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Birth Weight; Burkina Faso; Drug Combinations; Ethanolamines; Female; Fetal Development; Fluorenes; Follow-Up Studies; Ghana; Humans; Infant, Newborn; Malaria; Malawi; Mefloquine; Placentation; Pregnancy; Pregnancy Complications, Parasitic; Prenatal Exposure Delayed Effects; Quinolines; Zambia

2015
Opposite malaria and pregnancy effect on oral bioavailability of artesunate - a population pharmacokinetic evaluation.
    British journal of clinical pharmacology, 2015, Volume: 80, Issue:4

    Topics: Administration, Intravenous; Administration, Oral; Antimalarials; Artemisinins; Artesunate; Biological Availability; Female; Humans; Malaria; Models, Biological; Postpartum Period; Pregnancy; Pregnancy Complications, Parasitic

2015
Validation and pharmacokinetic application of a high-performance liquid chromatographic technique for determining the concentrations of amodiaquine and its metabolite in plasma of patients treated with oral fixed-dose amodiaquine-artesunate combination in
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:9

    Topics: Administration, Oral; Adult; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Chromatography, High Pressure Liquid; Drug Combinations; Female; Humans; Malaria; Malaria, Falciparum; Male; Nigeria; Young Adult

2015
Safety and efficacy of re-treatments with pyronaridine-artesunate in African patients with malaria: a substudy of the WANECAM randomised trial.
    The Lancet. Infectious diseases, 2016, Volume: 16, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Artesunate; Burkina Faso; Child; Child, Preschool; Drug Combinations; Female; Guinea; Humans; Infant; Malaria; Male; Mali; Middle Aged; Naphthyridines; Plasmodium; Retreatment; Treatment Outcome; Young Adult

2016
Artesunate-mefloquine versus chloroquine for treatment of uncomplicated Plasmodium knowlesi malaria in Malaysia (ACT KNOW): an open-label, randomised controlled trial.
    The Lancet. Infectious diseases, 2016, Volume: 16, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Therapy, Combination; Female; Humans; Malaria; Malaysia; Male; Mefloquine; Middle Aged; Plasmodium knowlesi; Young Adult

2016
Population Pharmacokinetics of Pyronaridine in Pediatric Malaria Patients.
    Antimicrobial agents and chemotherapy, 2015, Dec-14, Volume: 60, Issue:3

    Topics: Adolescent; Antimalarials; Area Under Curve; Artemisinins; Artesunate; Child; Child, Preschool; Female; Humans; Infant; Malaria; Malaria, Falciparum; Malaria, Vivax; Male; Models, Theoretical; Naphthyridines

2015
Factors influencing willingness to participate in new drug trial studies: a study among parents whose children were recruited into these trials in northern Ghana.
    BMC research notes, 2016, Mar-03, Volume: 9

    Topics: Administration, Rectal; Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Child; Community Health Services; Female; Ghana; Humans; Informed Consent; Malaria; Male; Middle Aged; Motivation; Parents; Patient Participation

2016
Effect of quinine and artesunate combination therapy on platelet count of children with severe malaria.
    Paediatrics and international child health, 2017, Volume: 37, Issue:2

    Topics: Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Coma; Drug Therapy, Combination; Female; Humans; Incidence; Infant; Malaria; Male; Platelet Count; Quinine; Thrombocytopenia; Treatment Outcome

2017
Compliance With Referral Advice After Treatment With Prereferral Rectal Artesunate: A Study in 3 Sub-Saharan African Countries.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2016, Dec-15, Volume: 63, Issue:suppl 5

    Topics: Administration, Rectal; Africa South of the Sahara; Antimalarials; Artemisinins; Artesunate; Child, Preschool; Female; Humans; Infant; Malaria; Male; Patient Acceptance of Health Care; Patient Compliance; Referral and Consultation

2016
Quantifying and Valuing Community Health Worker Time in Improving Access to Malaria Diagnosis and Treatment.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2016, Dec-15, Volume: 63, Issue:suppl 5

    Topics: Adult; Antimalarials; Artemisinins; Artesunate; Burkina Faso; Community Health Workers; Diagnostic Tests, Routine; Female; Humans; Malaria; Male; Middle Aged; Nigeria; Rural Population; Surveys and Questionnaires; Time Factors; Uganda; Young Adult

2016
Pre-referral Rectal Artesunate Treatment by Community-Based Treatment Providers in Ghana, Guinea-Bissau, Tanzania, and Uganda (Study 18): A Cluster-Randomized Trial.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2016, Dec-15, Volume: 63, Issue:suppl 5

    Topics: Administration, Rectal; Antimalarials; Artemisinins; Artesunate; Child, Preschool; Community Health Workers; Female; Ghana; Guinea-Bissau; Humans; Infant; Malaria; Male; Referral and Consultation; Tanzania; Uganda

2016
An open label, randomised trial of artesunate+amodiaquine, artesunate+chlorproguanil-dapsone and artemether-lumefantrine for the treatment of uncomplicated malaria.
    PloS one, 2008, Jun-25, Volume: 3, Issue:6

    Topics: Amodiaquine; Antimalarials; Artemether; Artemisinins; Artesunate; Child; Child, Preschool; Dapsone; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Infant; Lumefantrine; Malaria; Male; Polymerase Chain Reaction; Proguanil; Treatment Outcome

2008
Efficacy, safety and tolerability of artesunate-mefloquine in the treatment of uncomplicated Plasmodium falciparum malaria in four geographic zones of Nigeria.
    Malaria journal, 2008, Sep-09, Volume: 7

    Topics: Antimalarials; Artemisinins; Artesunate; Drug Therapy, Combination; Humans; Malaria; Mefloquine; Nigeria; Parasitemia; Rural Population; Time Factors

2008
Seasonal intermittent preventive treatment for the prevention of anaemia and malaria in Ghanaian children: a randomized, placebo controlled trial.
    PloS one, 2008, Volume: 3, Issue:12

    Topics: Amodiaquine; Anemia; Antimalarials; Artemisinins; Artesunate; Child, Preschool; Drug Combinations; Ghana; Humans; Infant; Kaplan-Meier Estimate; Malaria; Placebos; Pyrimethamine; Seasons; Sulfadoxine

2008
Cost-effectiveness of artesunate for the treatment of severe malaria.
    Tropical medicine & international health : TM & IH, 2009, Volume: 14, Issue:3

    Topics: Antimalarials; Artemisinins; Artesunate; Asia, Southeastern; Cost-Benefit Analysis; Drug Costs; Health Care Costs; Humans; Malaria; Quinine; Treatment Outcome

2009
Randomized trial of artesunate+amodiaquine, sulfadoxine-pyrimethamine+amodiaquine, chlorproguanal-dapsone and SP for malaria in pregnancy in Tanzania.
    PloS one, 2009, Volume: 4, Issue:4

    Topics: Adult; Amodiaquine; Artemisinins; Artesunate; Dapsone; Drug Combinations; Drug Therapy, Combination; Female; Humans; Malaria; Pregnancy; Pregnancy Complications, Parasitic; Proguanil; Pyrimethamine; Sulfadoxine; Tanzania; Young Adult

2009
Population pharmacokinetics of artesunate and amodiaquine in African children.
    Malaria journal, 2009, Aug-20, Volume: 8

    Topics: Africa; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Biological Availability; Biotransformation; Child, Preschool; Drug Combinations; Female; Humans; Infant; Malaria; Male; Plasma; Prospective Studies; Time Factors; Treatment Outcome

2009
Azithromycin plus artesunate versus artemether-lumefantrine for treatment of uncomplicated malaria in Tanzanian children: a randomized, controlled trial.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2009, Oct-15, Volume: 49, Issue:8

    Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Azithromycin; Child, Preschool; Drug Therapy, Combination; Ethanolamines; Female; Fever of Unknown Origin; Fluorenes; Humans; Infant; Lumefantrine; Malaria; Male; Tanzania; Treatment Outcome

2009
Effectiveness of combined intermittent preventive treatment for children and timely home treatment for malaria control.
    Malaria journal, 2009, Dec-11, Volume: 8

    Topics: Adult; Amodiaquine; Animals; Antimalarials; Artemisinins; Artesunate; Caregivers; Child, Preschool; Drug Administration Schedule; Female; Fever; Ghana; Humans; Infant; Malaria; Male; Parasitemia; Plasmodium falciparum; Prevalence; Surveys and Questionnaires; Time Factors; Treatment Outcome

2009
Intermittent preventive treatment in infants for the prevention of malaria in rural Western kenya: a randomized, double-blind placebo-controlled trial.
    PloS one, 2010, Apr-02, Volume: 5, Issue:4

    Topics: Anemia; Antimalarials; Artemisinins; Artesunate; Dapsone; Double-Blind Method; Drug Combinations; Humans; Incidence; Infant; Kenya; Malaria; Premedication; Proguanil; Pyrimethamine; Sulfadoxine; Treatment Outcome

2010
Use of area under the curve to evaluate the effects of antimalarial drugs on malaria-associated anemia after treatment.
    American journal of therapeutics, 2011, Volume: 18, Issue:3

    Topics: Amodiaquine; Anemia; Antimalarials; Area Under Curve; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Child; Child, Preschool; Drug Combinations; Ethanolamines; Female; Fluorenes; Hematocrit; Humans; Infant; Malaria; Malaria, Falciparum; Male; Mefloquine; Nigeria; Plasmodium falciparum

2011
Incidence of malaria and efficacy of combination antimalarial therapies over 4 years in an urban cohort of Ugandan children.
    PloS one, 2010, Jul-30, Volume: 5, Issue:7

    Topics: Amodiaquine; Antimalarials; Artemether; Artemisinins; Artesunate; Child; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Incidence; Infant; Lumefantrine; Malaria; Male; Pyrimethamine; Sulfadoxine; Treatment Outcome; Uganda

2010
Artesunate suppositories: an option for severe malaria.
    Prescrire international, 2010, Volume: 19, Issue:107

    Topics: Antimalarials; Artemisinins; Artesunate; Child; Double-Blind Method; Humans; Malaria; Suppositories

2010
Cost effectiveness of seasonal intermittent preventive treatment using amodiaquine & artesunate or sulphadoxine-pyrimethamine in Ghanaian children.
    PloS one, 2010, Aug-17, Volume: 5, Issue:8

    Topics: Amodiaquine; Anemia; Antimalarials; Artemisinins; Artesunate; Child, Preschool; Cost-Benefit Analysis; Drug Combinations; Ghana; Humans; Infant; Malaria; Preventive Health Services; Pyrimethamine; Seasons; Sulfadoxine

2010
Artesunate dose escalation for the treatment of uncomplicated malaria in a region of reported artemisinin resistance: a randomized clinical trial.
    PloS one, 2011, Volume: 6, Issue:5

    Topics: Adolescent; Adult; Amebicides; Antimalarials; Artemisinins; Artesunate; Cambodia; Dose-Response Relationship, Drug; Drug Resistance; Female; Humans; Malaria; Male; Maximum Tolerated Dose; Neutropenia; Parasitemia; Young Adult

2011
A cluster-randomized trial of mass drug administration with a gametocytocidal drug combination to interrupt malaria transmission in a low endemic area in Tanzania.
    Malaria journal, 2011, Aug-24, Volume: 10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Endemic Diseases; Female; Humans; Infant; Malaria; Male; Microscopy; Middle Aged; Parasitemia; Placebos; Primaquine; Pyrimethamine; Sulfadoxine; Tanzania; Treatment Outcome; Young Adult

2011
Effects of amodiaquine and artesunate on sulphadoxine-pyrimethamine pharmacokinetic parameters in children under five in Mali.
    Malaria journal, 2011, Sep-21, Volume: 10

    Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Blood Chemical Analysis; Child, Preschool; Drug Combinations; Drug Interactions; Female; Half-Life; Humans; Infant; Malaria; Male; Mali; Pyrimethamine; Sulfadoxine

2011
Pharmacokinetics and pharmacodynamics of intravenous artesunate during severe malaria treatment in Ugandan adults.
    Malaria journal, 2012, Apr-27, Volume: 11

    Topics: Adult; Antimalarials; Artemisinins; Artesunate; Chromatography, Liquid; Female; Humans; Injections, Intravenous; Malaria; Male; Plasma; Tandem Mass Spectrometry; Uganda

2012
Glucose-6-phosphate dehydrogenase deficiency, chlorproguanil-dapsone with artesunate and post-treatment haemolysis in African children treated for uncomplicated malaria.
    Malaria journal, 2012, Jul-10, Volume: 11

    Topics: Africa South of the Sahara; Anemia, Hemolytic; Antimalarials; Artemisinins; Artesunate; Case-Control Studies; Child, Preschool; Dapsone; Drug Combinations; Drug Therapy, Combination; Glucosephosphate Dehydrogenase Deficiency; Humans; Infant; Malaria; Male; Proguanil

2012
A longitudinal trial comparing chloroquine as monotherapy or in combination with artesunate, azithromycin or atovaquone-proguanil to treat malaria.
    PloS one, 2012, Volume: 7, Issue:8

    Topics: Antimalarials; Artemisinins; Artesunate; Atovaquone; Azithromycin; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Endpoint Determination; Female; Genotyping Techniques; Humans; Infant; Longitudinal Studies; Malaria; Male; Proguanil

2012
Randomized, open-label trial of primaquine against vivax malaria relapse in Indonesia.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:3

    Topics: Adult; Antimalarials; Artemisinins; Artesunate; Drug Administration Schedule; Drug Dosage Calculations; Drug Resistance; Drug Therapy, Combination; Humans; Indonesia; Malaria; Malaria, Vivax; Male; Military Personnel; Plasmodium vivax; Primaquine; Quinine; Quinolines; Secondary Prevention

2013
Evidence for the efficacy of artesunate in asymptomatic Plasmodium malariae infections.
    The Journal of antimicrobial chemotherapy, 2002, Volume: 50, Issue:5

    Topics: Adolescent; Animals; Artemisinins; Artesunate; Child; Double-Blind Method; Female; Humans; Malaria; Male; Plasmodium malariae; Sesquiterpenes

2002
Disposition of artesunate and dihydroartemisinin after administration of artesunate suppositories in children from Papua New Guinea with uncomplicated malaria.
    Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:8

    Topics: Aging; alpha-Thalassemia; Antimalarials; Artemisinins; Artesunate; Body Weight; Child; Chromatography, High Pressure Liquid; Female; Genotype; Half-Life; Humans; Malaria; Male; Models, Statistical; Papua New Guinea; Population; Sesquiterpenes; Sex Characteristics; Spectrometry, Mass, Electrospray Ionization; Suppositories; Tissue Distribution

2004
Investigation of bioavailability, pharmacokinetics and safety of new pediatric formulations of artesunate and mefloquine.
    The Southeast Asian journal of tropical medicine and public health, 2005, Volume: 36, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Biological Availability; Drug Therapy, Combination; Humans; Malaria; Male; Mefloquine; Pediatrics; Sesquiterpenes

2005
Antischistosomal efficacy of artesunate combination therapies administered as curative treatments for malaria attacks.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2007, Volume: 101, Issue:2

    Topics: Amodiaquine; Animals; Anthelmintics; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Humans; Infant; Malaria; Pilot Projects; Pyrimethamine; Schistosoma haematobium; Schistosomiasis haematobia; Sesquiterpenes; Sulfadoxine; Treatment Outcome

2007
Artesunate + amodiaquine and artesunate + sulphadoxine-pyrimethamine for treatment of uncomplicated malaria in Democratic Republic of Congo: a clinical trial with determination of sulphadoxine and pyrimethamine-resistant haplotypes.
    Tropical medicine & international health : TM & IH, 2006, Volume: 11, Issue:10

    Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Artesunate; Child, Preschool; Democratic Republic of the Congo; DNA, Protozoan; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Haplotypes; Humans; Infant; Malaria; Malaria, Falciparum; Male; Plasmodium; Polymerase Chain Reaction; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Outcome

2006
A comparative study on the efficacy of artesunate plus sulphadoxine/pyrimethamine versus artemether-lumefantrine in eastern Sudan.
    Malaria journal, 2007, Jul-15, Volume: 6

    Topics: Adolescent; Adult; Animals; Antigens, Protozoan; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Genotype; Humans; Malaria; Male; Merozoite Surface Protein 1; Plasmodium falciparum; Protozoan Proteins; Pyrimethamine; Sesquiterpenes; Sudan; Sulfadoxine; Treatment Outcome

2007
Primaquine clears submicroscopic Plasmodium falciparum gametocytes that persist after treatment with sulphadoxine-pyrimethamine and artesunate.
    PloS one, 2007, Oct-10, Volume: 2, Issue:10

    Topics: Adolescent; Animals; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Drug Combinations; Female; Humans; Malaria; Malaria, Falciparum; Male; Plasmodium falciparum; Primaquine; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Tanzania; Treatment Outcome

2007
High risk of neutropenia in HIV-infected children following treatment with artesunate plus amodiaquine for uncomplicated malaria in Uganda.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2008, Apr-01, Volume: 46, Issue:7

    Topics: Amodiaquine; Anti-HIV Agents; Antimalarials; Artemisinins; Artesunate; Chemoprevention; Child; Child, Preschool; Drug Therapy, Combination; HIV Infections; Humans; Infant; Malaria; Neutropenia; Sesquiterpenes; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination; Uganda

2008
Antimalarial efficacy and mode of action of qinghaosu and its derivatives in experimental models. China Cooperative Research Group on qinghaosu and its derivatives as antimalarials.
    Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 1982, Volume: 2, Issue:1

    Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Erythrocytes; Malaria; Mice; Multicenter Studies as Topic; Plasmodium; Sesquiterpenes

1982
Clinical studies on the treatment of malaria with qinghaosu and its derivatives. China Cooperative Research Group on qinghaosu and its derivatives as antimalarials.
    Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 1982, Volume: 2, Issue:1

    Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Humans; Malaria; Multicenter Studies as Topic; Plasmodium falciparum; Plasmodium vivax; Sesquiterpenes

1982
A comparative clinical trial of sequential treatments of severe malaria with artesunate suppository followed by mefloquine in Thailand.
    The American journal of tropical medicine and hygiene, 1997, Volume: 57, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Drug Therapy, Combination; Female; Humans; Malaria; Malaria, Cerebral; Male; Mefloquine; Middle Aged; Sesquiterpenes; Single-Blind Method; Suppositories; Thailand

1997
[Rapid resolution of Plasmodium ovale malarial attacks using artesunate (Arsumax)].
    Medecine tropicale : revue du Corps de sante colonial, 1999, Volume: 59, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Anemia; Animals; Antimalarials; Artemisinins; Artesunate; Cameroon; Fever; Humans; Malaria; Middle Aged; Parasitemia; Plasmodium; Reticulocytes; Sesquiterpenes; Time Factors; Vertigo

1999
Effect of artemisinin on lipid peroxidation and fluidity of the erythrocyte membrane in malaria.
    Biological & pharmaceutical bulletin, 2000, Volume: 23, Issue:11

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Cyclic N-Oxides; Deferoxamine; Double-Blind Method; Erythrocyte Membrane; Humans; Lipid Peroxidation; Malaria; Malaria, Falciparum; Membrane Fluidity; Plasmodium falciparum; Sesquiterpenes; Thiobarbituric Acid Reactive Substances

2000
Bioavailability and preliminary clinical efficacy of intrarectal artesunate in Ghanaian children with moderate malaria.
    Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:2

    Topics: Administration, Rectal; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Female; Follow-Up Studies; Ghana; Humans; Infant; Injections, Intravenous; Malaria; Malaria, Cerebral; Male; Sesquiterpenes

2001

Other Studies

273 other study(ies) available for artesunic acid and Infections, Plasmodium

ArticleYear
MEFAS, a hybrid of artesunate-mefloquine active against asexual stages of Plasmodium vivax in field isolates, inhibits malaria transmission.
    International journal for parasitology. Drugs and drug resistance, 2021, Volume: 17

    Topics: Animals; Antimalarials; Artesunate; Humans; Malaria; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Plasmodium falciparum; Plasmodium vivax

2021
Cross-sectional study to predict subnational levels of health workers' knowledge about severe malaria treatment in Kenya.
    BMJ open, 2022, 01-05, Volume: 12, Issue:1

    Topics: Antimalarials; Artesunate; Bayes Theorem; Cross-Sectional Studies; Humans; Kenya; Malaria

2022
Delayed autoimmune haemolytic anaemia after artesunate therapy for severe malaria.
    BMJ case reports, 2022, Jan-17, Volume: 15, Issue:1

    Topics: Anemia, Hemolytic, Autoimmune; Antimalarials; Artesunate; Humans; Malaria; Malaria, Falciparum; Male; Middle Aged

2022
Readiness of the Kenyan public health sector to provide pre-referral care for severe paediatric malaria.
    Tropical medicine & international health : TM & IH, 2022, Volume: 27, Issue:3

    Topics: Antimalarials; Artesunate; Child; Humans; Kenya; Malaria; Public Health; Referral and Consultation

2022
Artesunate monotherapy versus artesunate plus quinine combination therapy for treatment of imported severe malaria: a TropNet retrospective cohort study.
    Infection, 2022, Volume: 50, Issue:4

    Topics: Adult; Antimalarials; Artemisinins; Artesunate; Child; Drug Therapy, Combination; Fever; Humans; Malaria; Malaria, Falciparum; Quinine; Retrospective Studies

2022
Parvovirus B19-associated transient aplastic crisis following P. falciparum malaria and post-artesunate delayed haemolysis in a returning traveller.
    Journal of travel medicine, 2022, 07-14, Volume: 29, Issue:4

    Topics: Artesunate; Hemolysis; Humans; Malaria; Malaria, Falciparum; Parvovirus B19, Human

2022
Dimeric Artesunate Glycerophosphocholine Conjugate Nano-Assemblies as Slow-Release Antimalarials to Overcome Kelch 13 Mutant Artemisinin Resistance.
    Antimicrobial agents and chemotherapy, 2022, 05-17, Volume: 66, Issue:5

    Topics: Antimalarials; Artemisinins; Artesunate; Cryoelectron Microscopy; Drug Resistance; Humans; Liposomes; Malaria; Malaria, Falciparum; Plasmodium falciparum

2022
Artesunate Resistance - An Emerging Threat.
    The Journal of the Association of Physicians of India, 2022, Volume: 70, Issue:4

    Topics: Adult; Antimalarials; Artesunate; Drug Resistance; Female; Humans; Malaria; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Pregnancy; Vomiting

2022
Artesunate-amodiaquine and artemether-lumefantrine for the treatment of uncomplicated falciparum malaria in Liberia: in vivo efficacy and frequency of molecular markers.
    Malaria journal, 2022, Apr-27, Volume: 21, Issue:1

    Topics: Amodiaquine; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artesunate; Child; Chloroquine; DNA Copy Number Variations; Female; Humans; Liberia; Malaria; Malaria, Falciparum; Membrane Transport Proteins; Plasmodium falciparum; Pregnancy

2022
Beneficial interaction between Ficus platyphylla and artesunate on cytokines TNF-α and IL-10 and oxidative stress in Plasmodium berghei-infected mice.
    Annals of parasitology, 2022, Volume: 68, Issue:1

    Topics: Animals; Antimalarials; Artesunate; Cytokines; Drug Combinations; Ficus; Interleukin-10; Malaria; Mice; Oxidative Stress; Parasitemia; Plasmodium berghei; Transferases; Tumor Necrosis Factor-alpha

2022
Prevalence of malaria among febrile patients and assessment of efficacy of artemether-lumefantrine and artesunate-amodiaquine for uncomplicated malaria in Dolisie, Republic of the Congo.
    Malaria journal, 2022, May-02, Volume: 21, Issue:1

    Topics: Amodiaquine; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artesunate; Child; Congo; Drug Combinations; Fever; Humans; Malaria; Parasitemia; Prevalence

2022
Prereferral rectal artesunate and referral completion among children with suspected severe malaria in the Democratic Republic of the Congo, Nigeria and Uganda.
    BMJ global health, 2022, Volume: 7, Issue:5

    Topics: Antimalarials; Artesunate; Child; Child, Preschool; Democratic Republic of the Congo; Humans; Malaria; Nigeria; Referral and Consultation; Uganda

2022
[Malaria and its importance in travel medicine].
    Deutsche medizinische Wochenschrift (1946), 2022, Volume: 147, Issue:12

    Topics: Antimalarials; Artesunate; Humans; Malaria; Malaria, Falciparum; Severity of Illness Index; Travel; Travel Medicine

2022
Artesunate and dihydroartemisinin-piperaquine treatment failure in a severe Plasmodium falciparum malaria case imported from Republic of Côte d'Ivoire.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2022, Volume: 122

    Topics: Aged; Antimalarials; Artemisinins; Artesunate; Cote d'Ivoire; Drug Combinations; Humans; Malaria; Malaria, Falciparum; Male; Piperazines; Plasmodium falciparum; Quinolines; Treatment Failure

2022
Stakeholder perceptions on the deployment of multiple first-line therapies for uncomplicated malaria: a qualitative study in the health district of Kaya, Burkina Faso.
    Malaria journal, 2022, Jun-27, Volume: 21, Issue:1

    Topics: Amodiaquine; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Burkina Faso; Drug Combinations; Drug Therapy, Combination; Humans; Malaria; Malaria, Falciparum; Naphthyridines

2022
Stopping prereferral rectal artesunate - a grave error.
    BMJ global health, 2022, Volume: 7, Issue:7

    Topics: Antimalarials; Artesunate; Humans; Malaria; Referral and Consultation

2022
Prospective observational study to evaluate the clinical and biological safety profile of pyronaridine-artesunate in a rural health district in Burkina Faso.
    Pharmacology research & perspectives, 2022, Volume: 10, Issue:4

    Topics: Antimalarials; Artemisinins; Artesunate; Burkina Faso; Chemical and Drug Induced Liver Injury; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Humans; Malaria; Naphthyridines; Rural Health

2022
Malaria Surveillance - United States, 2018.
    Morbidity and mortality weekly report. Surveillance summaries (Washington, D.C. : 2002), 2022, 09-02, Volume: 71, Issue:8

    Topics: Antimalarials; Artesunate; Biomarkers; Female; Humans; Malaria; Military Personnel; Population Surveillance; Pregnancy; United States

2022
Post-artesunate Delayed Hemolysis in Patients With Severe Malaria in the United States-April 2019 Through July 2021.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2023, 02-08, Volume: 76, Issue:3

    Topics: Antimalarials; Artemisinins; Artesunate; Hemolysis; Humans; Malaria; Malaria, Falciparum; United States

2023
Artesunate drug-loaded 2D nano-shuttle landing on RBCs infected with malaria parasites.
    Biomaterials science, 2022, Oct-11, Volume: 10, Issue:20

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Erythrocytes; Lactate Dehydrogenases; Malaria; Nanostructures; Parasites; Pharmaceutical Preparations; Succinates

2022
Food and Drug Administration Approval of Artesunate for Severe Malaria: Enough to Achieve Best Practice?
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2023, 02-08, Volume: 76, Issue:3

    Topics: Antimalarials; Artemisinins; Artesunate; Humans; Malaria; United States; United States Food and Drug Administration

2023
Malaria: Prevention, Diagnosis, and Treatment.
    American family physician, 2022, Volume: 106, Issue:3

    Topics: Animals; Artemisinins; Artesunate; Child; Female; Humans; Incidence; Malaria; Travel; United States

2022
Key factors predicting suspected severe malaria case management and health outcomes: an operational study in the Democratic Republic of the Congo.
    Malaria journal, 2022, Sep-27, Volume: 21, Issue:1

    Topics: Antimalarials; Artesunate; Case Management; Child; Child, Preschool; Democratic Republic of the Congo; Humans; Infant; Malaria

2022
Antioxidant activities of artesunate-procyanidin hybrid compound in erythrocyte and liver of Plasmodium berghei NK65-infected mice.
    Fundamental & clinical pharmacology, 2023, Volume: 37, Issue:2

    Topics: Animals; Antimalarials; Antioxidants; Artesunate; Erythrocytes; Liver; Malaria; Mice; Plasmodium berghei; Proanthocyanidins

2023
Acceptability of pre-referral rectal artesunate for severe malaria in children under 5 years by health workers and caregivers in the Democratic Republic of the Congo, Nigeria and Uganda.
    Malaria journal, 2022, Nov-10, Volume: 21, Issue:1

    Topics: Antimalarials; Artemisinins; Artesunate; Caregivers; Child; Child, Preschool; Community Health Workers; Democratic Republic of the Congo; Humans; Malaria; Nigeria; Referral and Consultation; Uganda

2022
Rectal artesunate as pre-referral treatment for severe malaria in sub-Saharan Africa: still a long way to go.
    The Lancet. Global health, 2023, Volume: 11, Issue:2

    Topics: Africa South of the Sahara; Antimalarials; Artesunate; Humans; Malaria; Malaria, Falciparum; Referral and Consultation

2023
Health system readiness and the implementation of rectal artesunate for severe malaria in sub-Saharan Africa: an analysis of real-world costs and constraints.
    The Lancet. Global health, 2023, Volume: 11, Issue:2

    Topics: Africa South of the Sahara; Antimalarials; Artemisinins; Artesunate; Humans; Malaria

2023
WHO should accelerate, not stall, rectal artesunate deployment for pre-referral treatment of severe malaria.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2023, 07-04, Volume: 117, Issue:7

    Topics: Administration, Rectal; Antimalarials; Artemisinins; Artesunate; Child; Humans; Malaria; Referral and Consultation; World Health Organization

2023
Return to Travel in the Coronavirus Disease 2019 Pandemic Recovery Period and Implications for Imported Malaria: Reinforcing Prevention, Early Diagnosis, and Appropriate Treatment of Malaria.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2023, 04-03, Volume: 76, Issue:7

    Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artesunate; COVID-19; COVID-19 Testing; Early Diagnosis; Humans; Malaria; Malaria, Falciparum; Pandemics; Travel; United States

2023
Congenital severe malaria: Artesunate for successful and safe treatment in neonates: A case report.
    Tropical doctor, 2023, Volume: 53, Issue:2

    Topics: Antimalarials; Artesunate; Humans; Infant, Newborn; Infant, Newborn, Diseases; Malaria; Malaria, Falciparum

2023
Health worker compliance with severe malaria treatment guidelines in the context of implementing pre-referral rectal artesunate in the Democratic Republic of the Congo, Nigeria, and Uganda: An operational study.
    PLoS medicine, 2023, Volume: 20, Issue:2

    Topics: Antimalarials; Artesunate; Child; Child, Preschool; Democratic Republic of the Congo; Humans; Malaria; Nigeria; Referral and Consultation; Uganda

2023
Adherence to severe malaria treatment guidelines in children at a Ugandan regional hospital: a baseline assessment for a malaria treatment quality improvement project.
    Malaria journal, 2023, Feb-25, Volume: 22, Issue:1

    Topics: Antimalarials; Artesunate; Child; Child, Preschool; Female; Hospitals; Humans; Malaria; Male; Quality Improvement; Uganda

2023
The five continuum of care criteria that should accompany rectal artesunate interventions: lessons learned from an implementation study in Malawi.
    Malaria journal, 2023, Mar-25, Volume: 22, Issue:1

    Topics: Antimalarials; Artesunate; Child; Community Health Workers; Continuity of Patient Care; Humans; Malaria; Malawi

2023
Case Report: Severe Optic Neuritis after Multiple Episodes of Malaria in a Traveler to Africa.
    The American journal of tropical medicine and hygiene, 2023, 05-03, Volume: 108, Issue:5

    Topics: Artesunate; Humans; Malaria; Male; Nigeria; Optic Neuritis; Steroids

2023
Pre-referral rectal artesunate is no "magic bullet" in weak health systems.
    BMC medicine, 2023, 03-30, Volume: 21, Issue:1

    Topics: Administration, Rectal; Antimalarials; Artemisinins; Artesunate; Bisacodyl; Child; Child, Preschool; Humans; Malaria; Referral and Consultation

2023
The CARAMAL study could not assess the effectiveness of rectal artesunate in treating suspected severe malaria.
    BMC medicine, 2023, 03-30, Volume: 21, Issue:1

    Topics: Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Humans; Malaria; Referral and Consultation

2023
Use of artesunate in the treatment of severe imported malaria in France: review of the effectiveness and real-life safety in two French university hospitals.
    BMC infectious diseases, 2023, May-25, Volume: 23, Issue:1

    Topics: Antimalarials; Artemisinins; Artesunate; France; Hospitals, University; Humans; Malaria; Malaria, Falciparum; Retrospective Studies

2023
Rectal artesunate for severe malaria, implementation research, Zambia.
    Bulletin of the World Health Organization, 2023, Jun-01, Volume: 101, Issue:6

    Topics: Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Community Health Workers; Humans; Malaria; Pilot Projects; Zambia

2023
Case Report: Severe Plasmodium vivax Malaria after Splenectomy.
    The American journal of tropical medicine and hygiene, 2023, 08-02, Volume: 109, Issue:2

    Topics: Artesunate; Humans; Malaria; Malaria, Vivax; Plasmodium falciparum; Plasmodium vivax; Splenectomy

2023
Synthesis and Characterization of Dimeric Artesunate Glycerol Monocaprylate Conjugate and Formulation of Nanoemulsion Preconcentrate.
    Molecules (Basel, Switzerland), 2023, Jul-04, Volume: 28, Issue:13

    Topics: Artesunate; Drug Delivery Systems; Emulsions; Glycerol; Humans; Malaria; Nanoparticles; Polymers

2023
Glutaraldehyde modified red blood cells delivering artesunate to the liver as a dual therapeutic and prophylactic antimalaria strategy.
    Journal of materials chemistry. B, 2023, 08-09, Volume: 11, Issue:31

    Topics: Animals; Artesunate; Erythrocytes; Glutaral; Liver; Malaria; Mice

2023
Evidence Based Optimal Dosing of Intravenous Artesunate in Children with Severe Falciparum Malaria.
    Clinical pharmacology and therapeutics, 2023, Volume: 114, Issue:6

    Topics: Administration, Intravenous; Adolescent; Antimalarials; Artesunate; Bayes Theorem; Child; Humans; Malaria; Malaria, Falciparum

2023
Investigation of new ferrocenyl-artesunate derivatives as antiparasitics.
    Dalton transactions (Cambridge, England : 2003), 2023, Nov-07, Volume: 52, Issue:43

    Topics: Amides; Antimalarials; Antiparasitic Agents; Artesunate; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum

2023
Antimalarial Agents Targeting Plasmodium falciparum Carbonic Anhydrase: Towards Artesunate Hybrid Compounds with Dual Mechanism of Action.
    ChemMedChem, 2023, Nov-02, Volume: 18, Issue:21

    Topics: Animals; Antimalarials; Artesunate; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Humans; Malaria; Malaria, Falciparum; Mice; Plasmodium falciparum; Protein Isoforms

2023
Variation in neutrophil levels and artemisinin-based combination therapy efficacy in West-Africa.
    Journal of infection in developing countries, 2023, 09-30, Volume: 17, Issue:9

    Topics: Africa; Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Drug Combinations; Ethanolamines; Humans; Malaria; Malaria, Falciparum; Neutropenia; Neutrophils; Parasitemia; Plasmodium falciparum; Prospective Studies

2023
Assessing caregivers' perceptions of treatment-seeking for suspected severe malaria in the Democratic Republic of the Congo.
    Malaria journal, 2023, Oct-13, Volume: 22, Issue:1

    Topics: Anemia; Artesunate; Caregivers; Child; Cross-Sectional Studies; Democratic Republic of the Congo; Humans; Infant; Malaria; Patient Acceptance of Health Care

2023
[Extracorporeal support treatment in severe malaria].
    Medicina, 2023, Volume: 83, Issue:5

    Topics: Adult; Antimalarials; Artesunate; Brain Diseases; Humans; Malaria; Malaria, Falciparum; Male

2023
Favorable outcome without corticosteroids during post-artesunate delayed hemolysis with positive direct antiglobulin test in severe imported Plasmodium falciparum malaria, France.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2023, Volume: 137

    Topics: Adrenal Cortex Hormones; Antimalarials; Artemisinins; Artesunate; Coombs Test; France; Hemolysis; Humans; Malaria; Malaria, Falciparum; Retrospective Studies

2023
Rectal artesunate suppositories for the pre-referral treatment of suspected severe malaria.
    PLoS medicine, 2023, Volume: 20, Issue:11

    Topics: Antimalarials; Artemisinins; Artesunate; Humans; Malaria; Referral and Consultation; Suppositories

2023
[Artesunate and severe malaria in paediatrics].
    Revue medicale de Liege, 2019, Volume: 74, Issue:10

    Topics: Antimalarials; Artemisinins; Artesunate; Child; Europe; Humans; Malaria; Pediatrics

2019
Determinants of post-malarial anemia in African children treated with parenteral artesunate.
    Scientific reports, 2019, 12-02, Volume: 9, Issue:1

    Topics: Anemia; Antimalarials; Artesunate; Blood Transfusion; Child; Child, Preschool; Erythropoietin; Female; Humans; Infant; Infusions, Parenteral; Malaria; Male; Parasitemia

2019
Use of rectal artesunate for severe malaria at the community level, Zambia.
    Bulletin of the World Health Organization, 2019, Dec-01, Volume: 97, Issue:12

    Topics: Administration, Rectal; Antimalarials; Artesunate; Child, Preschool; Community Health Workers; Cross-Sectional Studies; Humans; Infant; Malaria; Medically Underserved Area; Pilot Projects; Severity of Illness Index; Transportation; Zambia

2019
Anemia and transfusion requirements among Ugandan children with severe malaria treated with intravenous artesunate.
    Pediatric hematology and oncology, 2020, Volume: 37, Issue:2

    Topics: Administration, Intravenous; Anemia; Artesunate; Blood Transfusion; Child; Child, Preschool; Female; Humans; Malaria; Male; Prospective Studies; Uganda

2020
Intravenous artesunate plus oral dihydroartemisinin-piperaquine or intravenous quinine plus oral quinine for optimum treatment of severe malaria: lesson learnt from a field hospital in Timika, Papua, Indonesia.
    Malaria journal, 2019, Dec-30, Volume: 18, Issue:1

    Topics: Administration, Intravenous; Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Drug Combinations; Female; Humans; Indonesia; Infant; Infant, Newborn; Malaria; Male; Middle Aged; Quinine; Quinolines; Retrospective Studies; Young Adult

2019
Delayed haemolysis after treatment with intravenous artesunate in patients with severe malaria in India.
    Malaria journal, 2020, Jan-22, Volume: 19, Issue:1

    Topics: Administration, Intravenous; Adolescent; Adult; Anemia, Hemolytic; Antimalarials; Artesunate; Child; Child, Preschool; Female; Hemolysis; Humans; India; Infant; Malaria; Male; Middle Aged; Prospective Studies; Time Factors; Young Adult

2020
The End of the Artemisinin Era-We Should Aim at Malaria Eradication in Asia Using Free, Effective Treatment.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2021, 08-02, Volume: 73, Issue:3

    Topics: Amodiaquine; Artemisinins; Artesunate; Asia; Cambodia; Humans; Malaria; Plasmodium falciparum

2021
Clinical and In Vitro Resistance of Plasmodium falciparum to Artesunate-Amodiaquine in Cambodia.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2021, 08-02, Volume: 73, Issue:3

    Topics: Adult; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Asia; Cambodia; Child; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum; Prospective Studies

2021
Post-malarial anemia in Mozambican children treated with quinine or artesunate: A retrospective observational study.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2020, Volume: 96

    Topics: Administration, Intravenous; Adolescent; Anemia; Antimalarials; Artesunate; Child; Child, Preschool; Female; Humans; Infant; Malaria; Male; Mozambique; Quinine; Retrospective Studies

2020
Malaria in the third trimester and maternal-perinatal outcome.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2020, Volume: 151, Issue:1

    Topics: Adolescent; Adult; Anemia; Antimalarials; Artesunate; Asphyxia Neonatorum; Cameroon; Cohort Studies; Female; Fetal Death; Humans; Infant, Low Birth Weight; Infant, Newborn; Intensive Care Units, Neonatal; Malaria; Matched-Pair Analysis; Perinatal Death; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Trimester, Third; Premature Birth; Young Adult

2020
Efficacy and Safety of Intravenous Artesunate in Children With Severe Imported Malaria.
    The Pediatric infectious disease journal, 2020, Volume: 39, Issue:8

    Topics: Antimalarials; Artesunate; Child; Germany; Humans; Malaria; Retrospective Studies; Tertiary Care Centers

2020
Increased Sensitivity of Plasmodium falciparum to Artesunate/Amodiaquine Despite 14 Years as First-Line Malaria Treatment, Zanzibar.
    Emerging infectious diseases, 2020, Volume: 26, Issue:8

    Topics: Amodiaquine; Antimalarials; Artesunate; Asia; Drug Combinations; Drug Resistance; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum; Protozoan Proteins; Tanzania

2020
Predictors of health workers' knowledge about artesunate-based severe malaria treatment recommendations in government and faith-based hospitals in Kenya.
    Malaria journal, 2020, Jul-23, Volume: 19, Issue:1

    Topics: Artesunate; Clinical Competence; Drug Combinations; Health Personnel; Hospitals; Hospitals, Religious; Humans; Kenya; Malaria

2020
Treatment Approved for Severe Malaria.
    The American journal of nursing, 2020, Volume: 120, Issue:9

    Topics: Adult; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child; Drug Combinations; Drug Monitoring; Humans; Injections, Intravenous; Malaria; Severity of Illness Index; Treatment Outcome

2020
Maintaining focus on administering effective malaria treatment during the COVID-19 pandemic.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2020, 11-23, Volume: 111, Issue:1

    Topics: Administration, Intravenous; Antigens, Protozoan; Antimalarials; Artemether, Lumefantrine Drug Combination; Artesunate; COVID-19; Early Diagnosis; Early Medical Intervention; Humans; Malaria; Malaria, Falciparum; Microscopy; Point-of-Care Testing; Primaquine; Protozoan Proteins; SARS-CoV-2; Severity of Illness Index; South Africa

2020
Intravenous Artesunate for the Treatment of Severe Imported Malaria: Implementation, Efficacy, and Safety in 1391 Patients.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2021, 11-16, Volume: 73, Issue:10

    Topics: Antimalarials; Artemisinins; Artesunate; Female; Hemolysis; Humans; Malaria; Malaria, Falciparum; Pregnancy

2021
Effect of Body Weight and Age on the Pharmacokinetics of Dihydroartemisinin: Food and Drug Administration Basis for Dose Determination of Artesunate for Injection in Pediatric Patients With Severe Malaria.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2021, 09-07, Volume: 73, Issue:5

    Topics: Antimalarials; Artemisinins; Artesunate; Body Weight; Child; Humans; Malaria; Malaria, Falciparum; United States; United States Food and Drug Administration

2021
Antiplasmodial activity of Ethanolic extract of Cassia spectabilis DC leaf and its inhibition effect in Heme detoxification.
    BMC complementary medicine and therapies, 2021, Feb-19, Volume: 21, Issue:1

    Topics: Animals; Antimalarials; Artesunate; Cassia; Chloroquine; Heme; Ketones; Malaria; Male; Mice, Inbred BALB C; Phytotherapy; Piperidines; Plant Extracts; Plant Leaves; Plasmodium berghei; Plasmodium falciparum

2021
Development and Validation of an
    Antimicrobial agents and chemotherapy, 2021, 05-18, Volume: 65, Issue:6

    Topics: Adult; Africa; Antimalarials; Artesunate; Asia, Southeastern; Bayes Theorem; Child; Computer Simulation; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum

2021
Pyronaridine-artesunate real-world safety, tolerability, and effectiveness in malaria patients in 5 African countries: A single-arm, open-label, cohort event monitoring study.
    PLoS medicine, 2021, Volume: 18, Issue:6

    Topics: Adolescent; Adult; Africa; Antimalarials; Artesunate; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Drug Combinations; Female; Humans; Infant; Infant, Newborn; Liver Function Tests; Malaria; Male; Naphthyridines; Patient Safety; Product Surveillance, Postmarketing; Retrospective Studies; Time Factors; Treatment Outcome; Young Adult

2021
Murine pharmacokinetics and antimalarial pharmacodynamics of dihydroartemisinin trimer self-assembled nanoparticles.
    Parasitology research, 2021, Volume: 120, Issue:8

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Malaria; Mice; Nanoparticles; Plasmodium yoelii; Rats

2021
Safety and Effectiveness of Intravenous Artesunate for Treatment of Severe Malaria in the United States-April 2019 Through December 2020.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2021, 12-06, Volume: 73, Issue:11

    Topics: Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Female; Humans; Malaria; Malaria, Falciparum; Male; Middle Aged; United States; Young Adult

2021
INFLUENCE OF ARTESUNATE COMBINATIVE THERAPY CO-ADMINISTRATION WITH RUTIN ON INFLAMMATORY CYTOKINES AND IMMUNOGLOBULINS IN PLASMODIUM BERGHEI-INFECTED MICE.
    The Journal of parasitology, 2021, 07-01, Volume: 107, Issue:4

    Topics: Animals; Antimalarials; Antioxidants; Artesunate; Cytokines; Drug Therapy, Combination; Immunoglobulins; Leukocyte Count; Leukocytes; Malaria; Male; Mice; Plasmodium berghei; Rutin

2021
Effects of Artesunate on some biochemical parameters in pregnant albino Wistar rats challenged with lethal strain Plasmodium berghei NK65: Appreciating the activities of artemisinin drugs on key pregnancy hormone balance.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2017, Jul-05, Volume: 69, Issue:6

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Female; Hormones; Malaria; Plasmodium berghei; Pregnancy; Pregnancy Complications, Infectious; Rats; Rats, Wistar

2017
Adaptive immunity is essential in preventing recrudescence of Plasmodium yoelii malaria parasites after artesunate treatment.
    Cellular microbiology, 2017, Volume: 19, Issue:11

    Topics: Adaptive Immunity; Animals; Antimalarials; Artemisinins; Artesunate; B-Lymphocytes; CD4-Positive T-Lymphocytes; Disease Models, Animal; Drug Resistance; Female; Malaria; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Plasmodium yoelii; Recurrence

2017
Measuring the
    Science translational medicine, 2017, 07-05, Volume: 9, Issue:397

    Topics: Adolescent; Adult; Aged; Antigens, Protozoan; Artemisinins; Artesunate; Cytosol; Demography; Erythrocyte Membrane; Erythrocytes; Female; Hemolysis; Humans; Malaria; Male; Middle Aged; Plasmodium falciparum; Protozoan Proteins; Quinine; Young Adult

2017
Challenges in a product development partnership: a malaria treatment case study.
    Ciencia & saude coletiva, 2017, Volume: 22, Issue:7

    Topics: Antimalarials; Artemisinins; Artesunate; Brazil; Drug Combinations; Drug Design; Health Services Accessibility; Health Services Needs and Demand; Humans; Interviews as Topic; Malaria; Mefloquine; Public-Private Sector Partnerships

2017
Artemisia annua dried leaf tablets treated malaria resistant to ACT and i.v. artesunate: Case reports.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2017, Aug-15, Volume: 32

    Topics: Administration, Intravenous; Adolescent; Adult; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisia annua; Artemisinins; Artesunate; Child; Child, Preschool; Drug Combinations; Drug Resistance, Microbial; Ethanolamines; Female; Fluorenes; Humans; Infant; Malaria; Male; Middle Aged; Plant Leaves; Tablets; Treatment Outcome; Young Adult

2017
Characterising the effect of antimalarial drugs on the maturation and clearance of murine blood-stage Plasmodium parasites in vivo.
    International journal for parasitology, 2017, Volume: 47, Issue:14

    Topics: Adoptive Transfer; Animals; Antimalarials; Artemisinins; Artesunate; Dose-Response Relationship, Drug; Erythrocytes; Female; Flow Cytometry; Malaria; Mefloquine; Mice; Mice, Inbred C57BL; Parasitemia; Phagocytes; Plasmodium berghei; Plasmodium yoelii

2017
Artesunate-quercetin/luteolin dual drug nanofacilitated synergistic treatment for malaria: A plausible approach to overcome artemisinin combination therapy resistance.
    Medical hypotheses, 2017, Volume: 109

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Culicidae; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Female; Flavonoids; Humans; Lipids; Luteolin; Malaria; Models, Theoretical; Quercetin

2017
Efficacy of Lophira alata Leaf Extract and its Combination with Artesunate in Mice Prior Exposed to Plasmodium berghei.
    Drug research, 2018, Volume: 68, Issue:4

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Malaria; Mice; Ochnaceae; Phytotherapy; Plant Extracts; Plant Leaves; Plants, Medicinal; Plasmodium berghei

2018
Liposomes of dimeric artesunate phospholipid: A combination of dimerization and self-assembly to combat malaria.
    Biomaterials, 2018, Volume: 163

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Dimerization; Drug Carriers; Drug Liberation; Female; Glycerylphosphorylcholine; Humans; Liposomes; Malaria; Mice, Inbred BALB C; Nanoparticles; Particle Size

2018
Tropical diseases in the ICU: A syndromic approach to diagnosis and treatment.
    Journal of critical care, 2018, Volume: 46

    Topics: Artesunate; Azithromycin; Ceftriaxone; Child; Communicable Diseases; Critical Care; Dengue; Diagnosis, Differential; Doxycycline; Exanthema; Female; Fever; Geography; Humans; Intensive Care Units; Leptospirosis; Malaria; Male; Nervous System Diseases; Pregnancy; Shock, Hemorrhagic; Syndrome; Travel; Tropical Medicine; Typhoid Fever

2018
Caregivers' compliance with referral advice: evidence from two studies introducing mRDTs into community case management of malaria in Uganda.
    BMC health services research, 2018, 05-02, Volume: 18, Issue:1

    Topics: Adolescent; Antimalarials; Artemisinins; Artesunate; Caregivers; Case Management; Child; Child, Preschool; Community Health Workers; Diagnostic Tests, Routine; Female; Guideline Adherence; Humans; Infant; Malaria; Male; Randomized Controlled Trials as Topic; Referral and Consultation; Treatment Adherence and Compliance; Uganda

2018
Age-Related Clinical Spectrum of Plasmodium knowlesi Malaria and Predictors of Severity.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2018, 07-18, Volume: 67, Issue:3

    Topics: Acute Kidney Injury; Age Factors; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Female; Humans; Infant; Kidney; Malaria; Malaysia; Male; Parasitemia; Plasmodium knowlesi; Prospective Studies; Severity of Illness Index

2018
Community understanding of the concept of pre-referral treatment and how this impacts on referral related decision-making following the provision of rectal artesunate: a qualitative study in western Uganda.
    BMC health services research, 2018, 06-19, Volume: 18, Issue:1

    Topics: Antimalarials; Artesunate; Caregivers; Case Management; Child, Preschool; Community Health Workers; Decision Making; Female; Focus Groups; Health Facilities; Humans; Interviews as Topic; Malaria; Male; Qualitative Research; Referral and Consultation; Uganda

2018
Quantification of host-mediated parasite clearance during blood-stage Plasmodium infection and anti-malarial drug treatment in mice.
    International journal for parasitology, 2018, Volume: 48, Issue:12

    Topics: Animals; Antimalarials; Artesunate; Blood; Disease Models, Animal; Fluorescence; Malaria; Mefloquine; Mice; Models, Theoretical; Organisms, Genetically Modified; Parasite Load; Parasitemia; Plasmodium berghei; Staining and Labeling

2018
Assessing the consistency assumptions underlying network meta-regression using aggregate data.
    Research synthesis methods, 2019, Volume: 10, Issue:2

    Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Bayes Theorem; Data Interpretation, Statistical; Humans; Malaria; Models, Statistical; Network Meta-Analysis; Odds Ratio; Quinine; Regression Analysis; Reproducibility of Results; Research Design

2019
Artesunate-heparin conjugate based nanocapsules with improved pharmacokinetics to combat malaria.
    International journal of pharmaceutics, 2019, May-01, Volume: 562

    Topics: Animals; Antimalarials; Artesunate; Drug Delivery Systems; Drug Liberation; Erythrocytes; Female; Hemolysis; Heparin; Humans; Malaria; Mice, Inbred BALB C; Nanocapsules; Plasmodium falciparum

2019
Positive direct antiglobulin test in post-artesunate delayed haemolysis: more than a coincidence?
    Malaria journal, 2019, Apr-08, Volume: 18, Issue:1

    Topics: Administration, Intravenous; Adolescent; Adult; Anemia, Hemolytic; Antimalarials; Artesunate; Coombs Test; Female; Hemolysis; Humans; Malaria; Male; Middle Aged; Retrospective Studies; Spain

2019
[Descriptive study of malaria cases in the paediatric population in a reference hospital in Valencia, Spain, between 1993 and 2015].
    Anales de pediatria, 2020, Volume: 92, Issue:1

    Topics: Adolescent; Age Distribution; Antimalarials; Artemisinins; Artesunate; Atovaquone; Child; Child, Preschool; Drug Combinations; Equatorial Guinea; Female; Hospitals, Community; Humans; Infant; Malaria; Male; Proguanil; Quinine; Quinolines; Retrospective Studies; Sex Distribution; Spain; Symptom Assessment

2020
Hemolytic anemia in pediatric patients treated with artesunate for severe malaria.
    Enfermedades infecciosas y microbiologia clinica (English ed.), 2020, Volume: 38, Issue:3

    Topics: Anemia, Hemolytic; Artesunate; Child; Humans; Malaria

2020
Safety and efficacy of pyronaridine-artesunate in uncomplicated acute malaria: an integrated analysis of individual patient data from six randomized clinical trials.
    Malaria journal, 2013, Feb-21, Volume: 12

    Topics: Adolescent; Adult; Africa; Antimalarials; Artemisinins; Artesunate; Asia; Child; Child, Preschool; Clinical Trials, Phase III as Topic; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Infant; Malaria; Malaria, Falciparum; Malaria, Vivax; Male; Middle Aged; Naphthyridines; Randomized Controlled Trials as Topic; Treatment Outcome; Young Adult

2013
Malaria burden and artemisinin resistance in the mobile and migrant population on the Thai-Myanmar border, 1999-2011: an observational study.
    PLoS medicine, 2013, Volume: 10, Issue:3

    Topics: Antimalarials; Artemisinins; Artesunate; Climate; Community Health Workers; Cross-Sectional Studies; Drug Resistance; Female; Geography; Hospitalization; Humans; Malaria; Mefloquine; Myanmar; Plasmodium falciparum; Plasmodium vivax; Pregnancy; Pregnancy Complications, Parasitic; Prevalence; Rain; Reproducibility of Results; Temperature; Thailand; Transients and Migrants

2013
Antimalarial potential of China 30 and Chelidonium 30 in combination therapy against lethal rodent malaria parasite: Plasmodium berghei.
    Journal of complementary & integrative medicine, 2013, May-07, Volume: 10

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chelidonium; Chloroquine; Cinchona; Female; Homeopathy; Malaria; Male; Materia Medica; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Phytotherapy; Plant Extracts; Plasmodium berghei; Pyrimethamine

2013
Differential interactions of the broad spectrum drugs artemisinin, dihydroartemisinin and artesunate with serum albumin.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2013, Aug-15, Volume: 20, Issue:11

    Topics: Animals; Artemisinins; Artesunate; Cattle; Drug Therapy, Combination; Hydrophobic and Hydrophilic Interactions; Malaria; Protein Binding; Serum Albumin

2013
[From the Japanese Journal of Clinical Hematology, vol 54, no.5, May 2013, Picture in Clinical Hematology : Case of tropical malaria].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2013, Volume: 54, Issue:5

    Topics: Adult; Antimalarials; Artemisinins; Artesunate; Drug Therapy, Combination; Erythrocytes; Humans; Malaria; Male; Polymerase Chain Reaction; Quinine; Travel; Treatment Outcome

2013
Artesunate versus quinine in the treatment of severe imported malaria: comparative analysis of adverse events focussing on delayed haemolysis.
    Malaria journal, 2013, Jul-15, Volume: 12

    Topics: Adult; Anemia, Hemolytic; Antimalarials; Artemisinins; Artesunate; Drug-Related Side Effects and Adverse Reactions; Female; Germany; Human Migration; Humans; Malaria; Male; Middle Aged; Quinine; Retrospective Studies

2013
Roll out of intraveneous artesunate under named patient programmes in the Netherlands, Belgium and France.
    Orphanet journal of rare diseases, 2013, Sep-24, Volume: 8

    Topics: Administration, Intravenous; Antimalarials; Artemisinins; Artesunate; Belgium; France; Humans; Malaria; Netherlands; Rare Diseases

2013
Oxidative stress and micronutrient therapy in malaria: an in vivo study in Plasmodium berghei infected mice.
    Pakistan journal of biological sciences : PJBS, 2013, Feb-15, Volume: 16, Issue:4

    Topics: Animals; Antioxidants; Artemisinins; Artesunate; Chloroquine; Dose-Response Relationship, Drug; Female; Hemolysis; Malaria; Male; Mice; Micronutrients; Oxidative Stress; Plasmodium berghei; Selenium; Vitamin A; Vitamin E; Zinc

2013
In vitro and in vivo characterization of the antimalarial lead compound SSJ-183 in Plasmodium models.
    Drug design, development and therapy, 2013, Volume: 7

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Dose-Response Relationship, Drug; Drug Resistance; Female; Half-Life; Malaria; Mice; Oxazines; Plasmodium berghei; Plasmodium falciparum; Pyridines

2013
Hypothesized cause of delayed hemolysis associated with intravenous artesunate.
    Medical hypotheses, 2014, Volume: 82, Issue:2

    Topics: Administration, Intravenous; Anemia; Anemia, Hemolytic; Animals; Antimalarials; Artemisinins; Artesunate; Erythrocytes; Haplorhini; Hemoglobins; Hemolysis; Humans; Malaria; Rats; Reticulocytes; Time Factors

2014
[Malaria].
    Der Internist, 2014, Volume: 55, Issue:2

    Topics: Antimalarials; Artemisinins; Artesunate; Atovaquone; Drug Therapy, Combination; Humans; Malaria; Prevalence; Proguanil

2014
Disposition of amodiaquine and desethylamodiaquine in HIV-infected Nigerian subjects on nevirapine-containing antiretroviral therapy.
    The Journal of antimicrobial chemotherapy, 2014, Volume: 69, Issue:5

    Topics: Adolescent; Adult; Amodiaquine; Anti-Retroviral Agents; Antimalarials; Antiretroviral Therapy, Highly Active; Artemisinins; Artesunate; Chromatography, High Pressure Liquid; Drug Interactions; Female; HIV Infections; Humans; Lamivudine; Malaria; Male; Middle Aged; Nevirapine; Nigeria; Plasma; Young Adult; Zidovudine

2014
Formulation development and evaluation of the anti-malaria properties of sustained release artesunate-loaded solid lipid microparticles based on phytolipids.
    Drug delivery, 2015, Volume: 22, Issue:5

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Delayed-Action Preparations; Disease Models, Animal; Drug Carriers; Malaria; Mice; Microspheres; Particle Size; Plant Oils; Plasmodium berghei; Scattering, Small Angle; Soybean Oil; X-Ray Diffraction

2015
Evaluation of haematological changes in Plasmodium-berghei-infected mice administered with aqueous extract of Phyllantus amarus.
    Pakistan journal of biological sciences : PJBS, 2013, Jun-01, Volume: 16, Issue:11

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Body Weight; Disease Models, Animal; Dose-Response Relationship, Drug; Erythrocyte Count; Female; Hematocrit; Leukocyte Count; Malaria; Male; Mice; Phyllanthus; Phytotherapy; Plant Extracts; Plant Leaves; Plants, Medicinal; Plasmodium berghei; Time Factors

2013
Insights following change in drug policy: a descriptive study for antimalarial prescription practices in children of public sector health facilities in Jharkhand state of India.
    Journal of vector borne diseases, 2013, Volume: 50, Issue:4

    Topics: Adolescent; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Cross-Sectional Studies; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Health Facilities; Humans; Inappropriate Prescribing; India; Infant; Malaria; Male; Practice Patterns, Physicians'; Prescriptions; Prospective Studies; Public Sector; Pyrimethamine; Retrospective Studies; Sulfadoxine

2013
Introducing the concept of a new pre-referral treatment for severely ill febrile children at community level: a sociological approach in Guinea-Bissau.
    Malaria journal, 2014, Feb-06, Volume: 13

    Topics: Adult; Anti-Bacterial Agents; Antimalarials; Artemisinins; Artesunate; Drug Combinations; Female; Fever; Guinea-Bissau; Health Knowledge, Attitudes, Practice; Health Personnel; Humans; Infant; Infant, Newborn; Malaria; Mothers; Qualitative Research; Referral and Consultation; Rural Population; Suppositories; Surveys and Questionnaires

2014
Plasmodium vivax and Plasmodium falciparum ex vivo susceptibility to anti-malarials and gene characterization in Rondônia, West Amazon, Brazil.
    Malaria journal, 2014, Feb-28, Volume: 13

    Topics: Adult; Antimalarials; Artemisinins; Artesunate; Brazil; Chloroquine; DNA, Protozoan; Drug Resistance; Female; Genotype; Humans; Inhibitory Concentration 50; Malaria; Male; Mefloquine; Membrane Transport Proteins; Middle Aged; Multidrug Resistance-Associated Proteins; Mutation, Missense; Parasitic Sensitivity Tests; Plasmodium falciparum; Plasmodium vivax; Protozoan Proteins

2014
Human malaria in C57BL/6J mice: an in vivo model for chemotherapy studies.
    Indian journal of experimental biology, 2014, Volume: 52, Issue:1

    Topics: Animals; Artemisinins; Artesunate; Disease Models, Animal; Drug Resistance, Multiple; Female; Humans; Malaria; Mice; Mice, Inbred C57BL; Parasitemia; Plasmodium falciparum

2014
Needs-driven versus market-driven pharmaceutical innovation: the consortium for the development of a new medicine against malaria in Brazil.
    Developing world bioethics, 2014, Volume: 14, Issue:2

    Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Brazil; Drug Combinations; Drug Discovery; Drug Industry; Global Health; Health Care Sector; Health Services Needs and Demand; Humans; Internationality; Inventions; Malaria; Mefloquine; Neglected Diseases; Patents as Topic; Social Justice

2014
Rapid response to selection, competitive release and increased transmission potential of artesunate-selected Plasmodium chabaudi malaria parasites.
    PLoS pathogens, 2014, Volume: 10, Issue:4

    Topics: Adaptation, Physiological; Animals; Antimalarials; Artemisinins; Artesunate; Dose-Response Relationship, Drug; Drug Resistance; Malaria; Mice; Plasmodium chabaudi

2014
Synergistic effect of aqueous extract of Telfaria occidentalis on the biological activities of artesunate in Plasmodium berghei infected mice.
    African health sciences, 2013, Volume: 13, Issue:4

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Cucurbita; Drug Combinations; Drug Synergism; Malaria; Mice; Phytotherapy; Plant Extracts; Plant Leaves; Plants, Medicinal; Plasmodium berghei; Rats; Rats, Wistar

2013
Plasmodium malariae infection: a case of missed diagnosis.
    Journal of vector borne diseases, 2014, Volume: 51, Issue:2

    Topics: Artemisinins; Artesunate; Azure Stains; Child; Chromatography, Affinity; Diagnostic Errors; Drug Combinations; Female; Humans; India; Malaria; Plasmodium malariae; Polymerase Chain Reaction; Primaquine; Pyrimethamine; Sulfadoxine; Treatment Outcome

2014
Artesunate versus chloroquine infection-treatment-vaccination defines stage-specific immune responses associated with prolonged sterile protection against both pre-erythrocytic and erythrocytic Plasmodium yoelii infection.
    Journal of immunology (Baltimore, Md. : 1950), 2014, Aug-01, Volume: 193, Issue:3

    Topics: Animals; Anopheles; Antibodies, Protozoan; Antimalarials; Artemisia; Artemisinins; Artesunate; Chloroquine; Erythrocytes; Female; Malaria; Malaria Vaccines; Mice; Mice, Inbred BALB C; Phytotherapy; Plasmodium yoelii; Sporozoites; Time Factors; Vaccines, Attenuated

2014
Evaluation of dika wax-soybean oil-based artesunate-loaded lipospheres: in vitro-in vivo correlation studies.
    Journal of microencapsulation, 2014, Volume: 31, Issue:8

    Topics: Administration, Oral; Animals; Antimalarials; Artemisinins; Artesunate; Female; Hydrogen-Ion Concentration; Liposomes; Malaria; Male; Plant Oils; Rats; Rats, Wistar; Soybean Oil

2014
Low-cost, high-speed identification of counterfeit antimalarial drugs on paper.
    Talanta, 2014, Volume: 130

    Topics: Antimalarials; Artemisinins; Artesunate; Asia, Southeastern; Colorimetry; Counterfeit Drugs; Humans; Malaria; Microfluidics; Paper; Tablets

2014
Evaluation of a new handheld instrument for the detection of counterfeit artesunate by visual fluorescence comparison.
    The American journal of tropical medicine and hygiene, 2014, Volume: 91, Issue:5

    Topics: Antimalarials; Artemisinins; Artesunate; Chromatography, High Pressure Liquid; Confidence Intervals; Counterfeit Drugs; Fluorescence; Laos; Malaria; Optical Imaging; Sensitivity and Specificity

2014
Efficacy of intravenous methylene blue, intravenous artesunate, and their combination in preclinical models of malaria.
    Malaria journal, 2014, Oct-21, Volume: 13

    Topics: Administration, Intravenous; Animals; Antimalarials; Aotidae; Artemisinins; Artesunate; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Therapy, Combination; Female; Macaca mulatta; Malaria; Male; Methylene Blue; Plasmodium berghei; Plasmodium cynomolgi; Rats; Rats, Sprague-Dawley; Treatment Outcome

2014
Severe delayed hemolysis associated with regulated parenteral antimalarial drug.
    Emerging infectious diseases, 2015, Volume: 21, Issue:1

    Topics: Adult; Anemia, Hemolytic; Antimalarials; Artemisinins; Artesunate; Drug Administration Routes; Hemolysis; Humans; Malaria; Malaria, Falciparum; Male

2015
An autochthonous case of severe Plasmodium knowlesi malaria in Thailand.
    The American journal of tropical medicine and hygiene, 2015, Volume: 92, Issue:3

    Topics: Antimalarials; Artemisinins; Artesunate; Humans; Malaria; Male; Middle Aged; Plasmodium knowlesi; Thailand

2015
Preparedness for severe malaria.
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2015, Mar-24, Volume: 135, Issue:6

    Topics: Antimalarials; Artemisinins; Artesunate; Clinical Laboratory Techniques; Critical Illness; Hospitals; Humans; Malaria; Malaria, Falciparum; Microscopy; Patient Transfer; Quinine; Reagent Kits, Diagnostic; Surveys and Questionnaires; Time Factors

2015
Delayed-onset hemolytic anemia in patients with travel-associated severe malaria treated with artesunate, France, 2011-2013.
    Emerging infectious diseases, 2015, Volume: 21, Issue:5

    Topics: Adolescent; Anemia, Hemolytic; Antimalarials; Artemisinins; Artesunate; Blood Transfusion; Female; France; History, 21st Century; Humans; Malaria; Male; Travel; Treatment Outcome

2015
Replication of Plasmodium in reticulocytes can occur without hemozoin formation, resulting in chloroquine resistance.
    The Journal of experimental medicine, 2015, Jun-01, Volume: 212, Issue:6

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Cytoplasm; Drug Resistance; Erythrocytes; Female; Gene Deletion; Genes, Reporter; Hemeproteins; Hemoglobins; Malaria; Male; Mice; Mice, Inbred BALB C; Mutation; Plasmodium berghei; Reticulocytes

2015
Artesunate. The standard intravenous treatment for severe attacks of malaria.
    Prescrire international, 2014, Volume: 23, Issue:154

    Topics: Administration, Intravenous; Antimalarials; Artemisinins; Artesunate; Humans; Malaria; Quinine; Severity of Illness Index

2014
Synergistic effect of aqueous extract of Telfaria occidentalis on the biological activities of artesunate in Plasmodium berghei infected mice.
    African health sciences, 2014, Volume: 14, Issue:1

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Cucurbita; Drug Combinations; Drug Synergism; Malaria; Mice; Phytotherapy; Plant Extracts; Plant Leaves; Plants, Medicinal; Plasmodium berghei

2014
Intravenous Artesunate Reduces Parasite Clearance Time, Duration of Intensive Care, and Hospital Treatment in Patients With Severe Malaria in Europe: The TropNet Severe Malaria Study.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2015, Nov-01, Volume: 61, Issue:9

    Topics: Administration, Intravenous; Adult; Antimalarials; Artemisinins; Artesunate; Europe; Female; Humans; Malaria; Male; Quinine; Retrospective Studies; Time Factors; Treatment Outcome

2015
Intravenous Artesunate for the Treatment of Severe and Complicated Malaria in the United States: Clinical Use Under an Investigational New Drug Protocol.
    Annals of internal medicine, 2015, Oct-06, Volume: 163, Issue:7

    Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Drug Therapy, Combination; Drugs, Investigational; Female; Humans; Infant; Injections, Intravenous; Malaria; Male; Medication Adherence; Middle Aged; Parasitemia; Retrospective Studies; Treatment Outcome; United States; Young Adult

2015
Early and severe haemolysis after treatment with artesunate for severe malaria.
    Anaesthesia, critical care & pain medicine, 2015, Volume: 34, Issue:6

    Topics: Adult; Anemia, Hemolytic; Antimalarials; Artemisinins; Artesunate; Female; Hemolysis; Humans; Malaria

2015
Therapeutic efficacy of artesunate-amodiaquine and artemether-lumefantrine combinations in the treatment of uncomplicated malaria in two ecological zones in Ghana.
    Malaria journal, 2016, Jan-05, Volume: 15

    Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Drug Combinations; Ecology; Female; Ghana; Humans; Infant; Malaria; Male; Plasmodium falciparum; Prospective Studies

2016
Feasibility and acceptability of injectable artesunate for the treatment of severe malaria in the Democratic Republic of Congo.
    Malaria journal, 2016, Jan-08, Volume: 15

    Topics: Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Child; Democratic Republic of the Congo; Female; Humans; Injections, Intravenous; Malaria; Male; Treatment Outcome; Young Adult

2016
UK malaria treatment guidelines 2016.
    The Journal of infection, 2016, Volume: 72, Issue:6

    Topics: Adult; Antimalarials; Artemisinins; Artesunate; Breast Feeding; Child; Child, Preschool; Female; Humans; Malaria; Malaria, Falciparum; Malaria, Vivax; Plasmodium falciparum; Plasmodium vivax; Pregnancy; Pregnancy Complications, Parasitic; Primaquine; Travel

2016
Lopinavir/ritonavir enhanced the antimalarial activity of amodiaquine and artesunate in a mouse model of Plasmodium berghei.
    Journal of chemotherapy (Florence, Italy), 2016, Volume: 28, Issue:6

    Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Artesunate; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; HIV Protease Inhibitors; Lopinavir; Malaria; Mice; Plasmodium berghei; Ritonavir

2016
Inhibition of Glutathione Biosynthesis Sensitizes Plasmodium berghei to Antifolates.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:5

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Female; Glutamate-Cysteine Ligase; Glutathione; Malaria; Mice; Mice, Inbred BALB C; Plasmodium berghei; Pyrimethamine; Sulfadoxine

2016
Feasibility, acceptability and impact of integrating malaria rapid diagnostic tests and pre-referral rectal artesunate into the integrated community case management programme. A pilot study in Mchinji district, Malawi.
    Malaria journal, 2016, Mar-21, Volume: 15

    Topics: Administration, Rectal; Adult; Antimalarials; Artemisinins; Artesunate; Case Management; Child, Preschool; Chromatography, Affinity; Cross-Sectional Studies; Diagnostic Tests, Routine; Female; Humans; Infant; Malaria; Malawi; Male; Patient Acceptance of Health Care; Pilot Projects; Referral and Consultation

2016
The Community As the Patient in Malaria-Endemic Areas: Preempting Drug Resistance with Multiple First-Line Therapies.
    PLoS medicine, 2016, Volume: 13, Issue:3

    Topics: Antimalarials; Artemisinins; Artesunate; Drug Resistance, Microbial; Drug Therapy, Combination; Endemic Diseases; Health Policy; Humans; Malaria; Malaria, Falciparum; Mefloquine

2016
The role of red blood cell exchange for severe imported malaria in the artesunate era: a retrospective cohort study in a referral centre.
    Malaria journal, 2016, Apr-14, Volume: 15

    Topics: Administration, Intravenous; Adult; Antimalarials; Artemisinins; Artesunate; Cohort Studies; Erythrocyte Transfusion; Exchange Transfusion, Whole Blood; Female; Humans; Malaria; Male; Middle Aged; Retrospective Studies; Spain

2016
Transfusion-transmitted severe Plasmodium knowlesi malaria in a splenectomized patient with beta-thalassaemia major in Sabah, Malaysia: a case report.
    Malaria journal, 2016, Jul-12, Volume: 15, Issue:1

    Topics: Administration, Intravenous; Artemisinins; Artesunate; Female; Humans; Malaria; Malaysia; Plasmodium knowlesi; Splenectomy; Tetrahydrofolate Dehydrogenase; Transfusion Reaction; Treatment Outcome; Young Adult

2016
Adherence to national guidelines for the diagnosis and management of severe malaria: a nationwide, cross-sectional survey in Malawi, 2012.
    Malaria journal, 2016, 07-19, Volume: 15, Issue:1

    Topics: Administration, Intravenous; Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Child, Preschool; Cross-Sectional Studies; Disease Management; Female; Guideline Adherence; Health Services Research; Humans; Malaria; Malawi; Male; Quinine; Young Adult

2016
Artesunate-mefloquine: a malaria treatment for African children?
    The Lancet. Infectious diseases, 2016, Volume: 16, Issue:10

    Topics: Antimalarials; Artemisinins; Artesunate; Child; Drug Therapy, Combination; Humans; Malaria; Malaria, Falciparum; Mefloquine; Treatment Outcome

2016
Adherence to malaria diagnosis and treatment guidelines among healthcare workers in Ogun State, Nigeria.
    BMC public health, 2016, 08-19, Volume: 16, Issue:1

    Topics: Adult; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Case Management; Cross-Sectional Studies; Delivery of Health Care; Diagnostic Tests, Routine; Drug Prescriptions; Drug Therapy, Combination; Female; Guideline Adherence; Health Facilities; Health Personnel; Humans; Malaria; Male; Middle Aged; Nigeria; Practice Guidelines as Topic; Private Sector; Public Sector; Young Adult

2016
Comparative pharmacokinetics and pharmacodynamics of intravenous artelinate versus artesunate in uncomplicated Plasmodium coatneyi-infected rhesus monkey model.
    Malaria journal, 2016, 09-06, Volume: 15

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Disease Models, Animal; Macaca mulatta; Malaria; Splenectomy; Treatment Outcome; United States

2016
Intravascular haemolysis with haemoglobinuria in a splenectomized patient with severe Plasmodium knowlesi malaria.
    Malaria journal, 2016, Sep-09, Volume: 15

    Topics: Artemisinins; Artesunate; Hemoglobinuria; Hemolysis; Humans; Malaria; Malaysia; Male; Middle Aged; Plasmodium knowlesi; Splenectomy

2016
Health worker perspectives on the possible use of intramuscular artesunate for the treatment of severe malaria at lower-level health facilities in settings with poor access to referral facilities in Nigeria: a qualitative study.
    BMC health services research, 2016, 10-12, Volume: 16, Issue:1

    Topics: Adult; Antimalarials; Artemisinins; Artesunate; Attitude of Health Personnel; Case Management; Female; Health Facilities; Health Personnel; Humans; Injections, Intramuscular; Interviews as Topic; Malaria; Male; Middle Aged; Nigeria; Primary Health Care; Qualitative Research; Referral and Consultation

2016
Health worker and policy-maker perspectives on use of intramuscular artesunate for pre-referral and definitive treatment of severe malaria at health posts in Ethiopia.
    Malaria journal, 2016, Oct-18, Volume: 15, Issue:1

    Topics: Administrative Personnel; Adult; Antimalarials; Artemether; Artemisinins; Artesunate; Ethiopia; Female; Health Personnel; Humans; Injections, Intramuscular; Interviews as Topic; Malaria; Male; Quinine; Young Adult

2016
Feasibility of Malaria Diagnosis and Management in Burkina Faso, Nigeria, and Uganda: A Community-Based Observational Study.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2016, Dec-15, Volume: 63, Issue:suppl 5

    Topics: Administration, Oral; Antimalarials; Artemisinins; Artesunate; Burkina Faso; Child; Child, Preschool; Community Health Workers; Diagnostic Tests, Routine; Female; Humans; Infant; Malaria; Malaria, Falciparum; Male; Nigeria; Proteins; Referral and Consultation; Uganda

2016
Impact of Improving Community-Based Access to Malaria Diagnosis and Treatment on Household Costs.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2016, Dec-15, Volume: 63, Issue:suppl 5

    Topics: Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Burkina Faso; Child, Preschool; Community Health Workers; Family Characteristics; Female; Health Services Accessibility; Humans; Malaria; Male; Middle Aged; Nigeria; Surveys and Questionnaires; Uganda; Young Adult

2016
Training Community Health Workers to Manage Uncomplicated and Severe Malaria: Experience From 3 Rural Malaria-Endemic Areas in Sub-Saharan Africa.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2016, Dec-15, Volume: 63, Issue:suppl 5

    Topics: Administration, Rectal; Adult; Africa South of the Sahara; Antimalarials; Artemisinins; Artesunate; Burkina Faso; Community Health Workers; Female; Humans; Malaria; Male; Middle Aged; Nigeria; Rural Population; Uganda

2016
Compliance With Malaria Rapid Diagnostic Testing by Community Health Workers in 3 Malaria-Endemic Countries of Sub-Saharan Africa: An Observational Study.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2016, Dec-15, Volume: 63, Issue:suppl 5

    Topics: Administration, Rectal; Antimalarials; Artemisinins; Artesunate; Community Health Workers; Diagnostic Tests, Routine; Female; Humans; Malaria; Male; Patient Compliance

2016
Assessing Acceptability of a Diagnostic and Malaria Treatment Package Delivered by Community Health Workers in Malaria-Endemic Settings of Burkina Faso, Nigeria, and Uganda.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2016, Dec-15, Volume: 63, Issue:suppl 5

    Topics: Antimalarials; Artemisinins; Artesunate; Burkina Faso; Community Health Workers; Diagnostic Tests, Routine; Female; Humans; Malaria; Male; Nigeria; Uganda

2016
Severe Malaria in African Children - The Need for Continuing Investment.
    The New England journal of medicine, 2016, Dec-22, Volume: 375, Issue:25

    Topics: Africa South of the Sahara; Antimalarials; Artemisinins; Artesunate; Child; Clinical Trials as Topic; Fluid Therapy; Humans; Malaria

2016
The dangers of accepting a single diagnosis: case report of concurrent Plasmodium knowlesi malaria and dengue infection.
    Malaria journal, 2017, 01-03, Volume: 16, Issue:1

    Topics: Antimalarials; Artemisinins; Artesunate; Coinfection; Dengue; Dengue Virus; Doxycycline; Humans; Malaria; Malaysia; Male; Middle Aged; Plasmodium knowlesi; Thailand; Treatment Outcome

2017
Impact of Extended Duration of Artesunate Treatment on Parasitological Outcome in a Cytocidal Murine Malaria Model.
    Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:4

    Topics: Amodiaquine; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Disease Models, Animal; Female; Malaria; Mice; Mice, Inbred BALB C; Quinolines

2017
Adverse effects of mefloquine for the treatment of uncomplicated malaria in Thailand: A pooled analysis of 19, 850 individual patients.
    PloS one, 2017, Volume: 12, Issue:2

    Topics: Adolescent; Adult; Anorexia; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Dizziness; Dose-Response Relationship, Drug; Drug Combinations; Drug Therapy, Combination; Female; Host-Parasite Interactions; Humans; Malaria; Male; Mefloquine; Nausea; Outcome Assessment, Health Care; Plasmodium falciparum; Plasmodium vivax; Psychotic Disorders; Pyrimethamine; Sulfadoxine; Thailand; Vomiting; Young Adult

2017
Pharmacokinetic and pharmacodynamic evaluation of intramuscular artesunate in healthy beagle dogs.
    The American journal of tropical medicine and hygiene, 2008, Volume: 79, Issue:1

    Topics: Animals; Antimalarials; Area Under Curve; Artemisinins; Artesunate; Creatine Kinase; Dogs; Dose-Response Relationship, Drug; Drug Tolerance; Injections, Intramuscular; Malaria; Muscle, Skeletal

2008
Artesunate for malaria.
    The New England journal of medicine, 2008, Jul-17, Volume: 359, Issue:3

    Topics: Antimalarials; Artemisinins; Artesunate; Humans; Malaria; Sesquiterpenes; Time Factors; United States

2008
Artesunate for malaria.
    The New England journal of medicine, 2008, Jul-17, Volume: 359, Issue:3

    Topics: Absorption; Animals; Antimalarials; Artemisinins; Artesunate; Humans; Injections, Intramuscular; Malaria; Sesquiterpenes

2008
Artesunate for malaria.
    The New England journal of medicine, 2008, Jul-17, Volume: 359, Issue:3

    Topics: Antimalarials; Artemisinins; Artesunate; Developing Countries; Fraud; Humans; Malaria; Sesquiterpenes

2008
Detecting counterfeit antimalarial tablets by near-infrared spectroscopy.
    Journal of pharmaceutical and biomedical analysis, 2008, Nov-04, Volume: 48, Issue:3

    Topics: Antimalarials; Artemisinins; Artesunate; Calibration; Chromatography, High Pressure Liquid; Confidence Intervals; Drug Contamination; Drug Packaging; Fraud; Humans; Malaria; Reproducibility of Results; Spectroscopy, Near-Infrared; Tablets; Time Factors

2008
Synthesis, antimalarial activity, and intracellular targets of MEFAS, a new hybrid compound derived from mefloquine and artesunate.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:11

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Cell Line; Dose-Response Relationship, Drug; Humans; Magnetic Resonance Spectroscopy; Malaria; Malaria, Falciparum; Mefloquine; Mice; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum

2008
[Two cases of fulminant hepatitis during a curative treatment with an artesunate-amodiaquine combination].
    Medecine et maladies infectieuses, 2009, Volume: 39, Issue:1

    Topics: Adult; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Chemical and Drug Induced Liver Injury; Fatal Outcome; Female; Humans; Malaria

2009
Efficacy of monotherapies and artesunate-based combination therapies in children with uncomplicated malaria in Somalia.
    Acta tropica, 2009, Volume: 109, Issue:2

    Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Humans; Infant; Malaria; Male; Pyrimethamine; Somalia; Sulfadoxine; Treatment Outcome

2009
Pre-referral rectal artesunate in severe malaria.
    Lancet (London, England), 2009, Feb-14, Volume: 373, Issue:9663

    Topics: Administration, Rectal; Adult; Africa; Antimalarials; Artemisinins; Artesunate; Child, Preschool; Community Health Services; Health Services Accessibility; Humans; Malaria; Rural Health Services

2009
Does artesunate prolong the electrocardiograph QT interval in patients with severe malaria?
    The American journal of tropical medicine and hygiene, 2009, Volume: 80, Issue:1

    Topics: Adult; Antimalarials; Artemisinins; Artesunate; Blood Pressure; Electrocardiography; Ethanolamines; Fluorenes; Glasgow Coma Scale; Heart Rate; Humans; Long QT Syndrome; Lumefantrine; Malaria; Male; Patient Selection

2009
Plasmodium berghei: efficacy of 5-fluoroorotate in combination with commonly used antimalarial drugs in a mouse model.
    Experimental parasitology, 2009, Volume: 121, Issue:4

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Dapsone; Drug Synergism; Drug Therapy, Combination; Malaria; Male; Mice; Mice, Inbred ICR; Orotic Acid; Parasitemia; Plasmodium berghei; Pyrimethamine

2009
Malaria - change in therapeutic policy.
    The Indian journal of medical research, 2009, Volume: 129, Issue:2

    Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Combinations; Drug Resistance; Humans; Malaria; Pyrimethamine; Sulfadoxine; Treatment Outcome

2009
Advances in global biotechnology and local resources to treat malaria.
    Minnesota medicine, 2009, Volume: 92, Issue:2

    Topics: Antimalarials; Artemether; Artemisia; Artemisinins; Artesunate; Drug Approval; Drug Resistance, Multiple; Drugs, Investigational; Global Health; Humans; Malaria; Minnesota; Phytotherapy

2009
Pre-referral artesunate in severe malaria.
    Lancet (London, England), 2009, May-23, Volume: 373, Issue:9677

    Topics: Administration, Rectal; Antimalarials; Artemisinins; Artesunate; Humans; Malaria; Patient Selection; Placebos; Randomized Controlled Trials as Topic; Referral and Consultation; Research Design

2009
Drug resistance and in vitro susceptibility of Plasmodium falciparum in Thailand during 1988-2003.
    The Korean journal of parasitology, 2009, Volume: 47, Issue:2

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Humans; Malaria; Mefloquine; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinine; Thailand

2009
Factors influencing adherence to referral advice following pre-referral treatment with artesunate suppositories in children in rural Tanzania.
    Tropical medicine & international health : TM & IH, 2009, Volume: 14, Issue:7

    Topics: Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Caregivers; Female; Health Knowledge, Attitudes, Practice; Humans; Malaria; Male; Medication Adherence; Middle Aged; Referral and Consultation; Rural Health; Suppositories; Young Adult

2009
A stratified random survey of the proportion of poor quality oral artesunate sold at medicine outlets in the Lao PDR - implications for therapeutic failure and drug resistance.
    Malaria journal, 2009, Jul-28, Volume: 8

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chemistry Techniques, Analytical; Cross-Sectional Studies; Drug Resistance; Humans; Laos; Malaria; Random Allocation; Treatment Failure

2009
[Availability of antimalarial agents in Dutch hospitals].
    Nederlands tijdschrift voor geneeskunde, 2009, Volume: 153

    Topics: Antimalarials; Artemisinins; Artesunate; Humans; Malaria; Malaria, Falciparum; Netherlands; Pharmacy Service, Hospital; Quinine

2009
Successful introduction of artesunate combination therapy is not enough to fight malaria: results from an adherence study in Sierra Leone.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2010, Volume: 104, Issue:5

    Topics: Adolescent; Adult; Aged; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Caregivers; Child; Child, Preschool; Drug Therapy, Combination; Female; Health Knowledge, Attitudes, Practice; Humans; Infant; Malaria; Male; Medication Adherence; Middle Aged; Parents; Risk Factors; Sierra Leone; Surveys and Questionnaires; Young Adult

2010
The use of placebo in a trial of rectal artesunate as initial treatment for severe malaria patients en route to referral clinics: ethical issues.
    Journal of medical ethics, 2010, Volume: 36, Issue:2

    Topics: Administration, Rectal; Antimalarials; Artemisinins; Artesunate; Health Services Accessibility; Humans; Malaria; Medication Adherence; Placebos; Randomized Controlled Trials as Topic; Referral and Consultation; Rural Health; Suppositories

2010
Is it too soon to eliminate quinine?
    The Lancet. Infectious diseases, 2010, Volume: 10, Issue:3

    Topics: Adult; Africa; Anti-Infective Agents; Antimalarials; Artemisinins; Artesunate; Child; Humans; Malaria; Quinine

2010
Management of malaria and other severe infections in rural Africa and Asia.
    BMJ (Clinical research ed.), 2010, Mar-17, Volume: 340

    Topics: Administration, Rectal; Antimalarials; Artemisinins; Artesunate; Bangladesh; Ghana; Humans; Malaria; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Rural Health; Tanzania

2010
Dynamics of Plasmodium falciparum parasitemia regarding combined treatment regimens for acute uncomplicated malaria, Antioquia, Colombia.
    The American journal of tropical medicine and hygiene, 2010, Volume: 83, Issue:1

    Topics: Administration, Oral; Animals; Antimalarials; Artemisinins; Artesunate; Clinical Protocols; Colombia; Drug Therapy, Combination; Female; Humans; Malaria; Malaria, Falciparum; Male; Mefloquine; Parasitemia; Patient Compliance; Plasmodium falciparum; Primaquine; Treatment Outcome

2010
Cervical lymphadenopathy: a rare presentation of malaria.
    The Journal of the Association of Physicians of India, 2010, Volume: 58

    Topics: Adult; Artemisinins; Artesunate; Diagnosis, Differential; Doxycycline; Female; Fever; Humans; Incidental Findings; Lymphatic Diseases; Malaria; Plasmodium falciparum; Plasmodium vivax; Treatment Outcome

2010
Knowledge and acceptability of the rectal treatment route in Laos and its application for pre-referral emergency malaria treatment.
    Malaria journal, 2010, Nov-27, Volume: 9

    Topics: Administration, Rectal; Adult; Antimalarials; Artemisinins; Artesunate; Attitude of Health Personnel; Child, Preschool; Cross-Sectional Studies; Emergency Medical Services; Female; Health Knowledge, Attitudes, Practice; Humans; Infant; Laos; Malaria; Male; Patient Acceptance of Health Care

2010
Prereferral rectal artesunate for treatment of severe childhood malaria: a cost-effectiveness analysis.
    Lancet (London, England), 2010, Dec-04, Volume: 376, Issue:9756

    Topics: Administration, Rectal; Africa; Antimalarials; Artemisinins; Artesunate; Child, Preschool; Cost-Benefit Analysis; Health Services Accessibility; Humans; Infant; Infant, Newborn; Malaria; Referral and Consultation; Rural Population; Time Factors

2010
Cost-effective use of prereferral treatment for severe malaria.
    Lancet (London, England), 2010, Dec-04, Volume: 376, Issue:9756

    Topics: Administration, Rectal; Antimalarials; Artemisinins; Artesunate; Community Networks; Cost-Benefit Analysis; Delivery of Health Care; Endemic Diseases; Health Services Accessibility; Humans; Malaria

2010
Immunological consequences of intermittent preventive treatment against malaria in Senegalese preschool children.
    Malaria journal, 2010, Dec-17, Volume: 9

    Topics: Antibodies, Protozoan; Antimalarials; Artemisinins; Artesunate; Chemoprevention; Child, Preschool; Drug Combinations; Female; Humans; Immunoglobulin G; Infant; Malaria; Male; Placebos; Plasmodium falciparum; Pyrimethamine; Senegal; Sulfadoxine

2010
Drug dispensing practices during implementation of artemisinin-based combination therapy at health facilities in rural Tanzania, 2002-2005.
    Tropical medicine & international health : TM & IH, 2011, Volume: 16, Issue:3

    Topics: Adolescent; Age Factors; Antimalarials; Artemisinins; Artesunate; Case Management; Child; Child, Preschool; Drug Combinations; Drug Costs; Drug Prescriptions; Drug Therapy, Combination; Humans; Infant; Malaria; Practice Patterns, Physicians'; Prospective Studies; Pyrimethamine; Rural Health Services; Sulfadoxine; Tanzania

2011
Intermittent preventive therapy for malaria: arguments in favour of artesunate and sulphamethoxypyrazine - pyrimethamine combination.
    Malaria journal, 2011, Mar-29, Volume: 10

    Topics: Antimalarials; Artemisinins; Artesunate; Child; Drug Combinations; Drug Resistance, Multiple; Female; Humans; Infant; Malaria; Plasmodium; Pyrimethamine; Sulfalene

2011
Artesunate for severe malaria in African children.
    Lancet (London, England), 2011, Apr-02, Volume: 377, Issue:9772

    Topics: Africa; Antimalarials; Artemisinins; Artesunate; Bacteremia; Child; Child, Preschool; Humans; Malaria; Parasitemia; Severity of Illness Index

2011
Use artesunate not quinine to treat severe malaria, say experts.
    BMJ (Clinical research ed.), 2011, Apr-20, Volume: 342

    Topics: Antimalarials; Artemisinins; Artesunate; Drug Substitution; Humans; Malaria; Quinine

2011
Artesunate for severe malaria.
    Lancet (London, England), 2011, Apr-30, Volume: 377, Issue:9776

    Topics: Adult; Antimalarials; Artemisinins; Artesunate; Child; Drug Costs; Humans; Malaria; Quinine

2011
In vitro and in vivo assessment of the anti-malarial activity of Caesalpinia pluviosa.
    Malaria journal, 2011, May-02, Volume: 10

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Brazil; Caesalpinia; Cell Line; Cell Survival; Disease Models, Animal; Drug Synergism; Humans; Malaria; Mice; Mice, Inbred C57BL; Plant Bark; Plant Extracts; Plants, Medicinal; Plasmodium chabaudi; Plasmodium falciparum; Quercetin; Rodent Diseases

2011
The antiplasmodial activity of Anogeissus leiocarpus and its effect on oxidative stress and lipid profile in mice infected with Plasmodium bergheii.
    Parasitology research, 2012, Volume: 110, Issue:1

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Blood Chemical Analysis; Combretaceae; Disease Models, Animal; Lipids; Liver; Malaria; Mice; Oxidative Stress; Parasitemia; Plant Bark; Plant Extracts; Plasmodium berghei; Superoxide Dismutase; Treatment Outcome

2012
Responding to the evidence for the management of severe malaria.
    Tropical medicine & international health : TM & IH, 2011, Volume: 16, Issue:9

    Topics: Antimalarials; Artemisinins; Artesunate; Critical Illness; Evidence-Based Practice; Health Care Costs; Health Knowledge, Attitudes, Practice; Humans; Information Dissemination; Malaria; Practice Guidelines as Topic; Quinine; Training Support; World Health Organization

2011
Cost-effectiveness of parenteral artesunate for treating children with severe malaria in sub-Saharan Africa.
    Bulletin of the World Health Organization, 2011, Jul-01, Volume: 89, Issue:7

    Topics: Africa South of the Sahara; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Cost-Benefit Analysis; Health Care Costs; Humans; Infusions, Parenteral; Malaria; Outcome Assessment, Health Care; Severity of Illness Index

2011
Severe Plasmodium knowlesi malaria in a tertiary care hospital, Sabah, Malaysia.
    Emerging infectious diseases, 2011, Volume: 17, Issue:7

    Topics: Acute Kidney Injury; Adult; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Ethanolamines; Female; Fluorenes; Hospitals, Urban; Humans; Lumefantrine; Malaria; Malaysia; Microscopy; Middle Aged; Parasitemia; Patient Selection; Plasmodium knowlesi; Polymerase Chain Reaction; Quinine; Respiratory Distress Syndrome; Severity of Illness Index; Shock; Survival Rate

2011
From quinine to artesunate in Africa.
    The Lancet. Infectious diseases, 2011, Volume: 11, Issue:6

    Topics: Africa; Antimalarials; Artemisinins; Artesunate; Humans; Malaria; Quinine; World Health Organization

2011
Parenteral artesunate access programme aims at reducing malaria fatality rates in South Africa.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2011, Volume: 101, Issue:4

    Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Artesunate; Female; Health Services Accessibility; Humans; Infusions, Parenteral; Malaria; Male; Middle Aged; South Africa; Young Adult

2011
Pre-referral rectal artesunate in severe malaria: flawed trial.
    Trials, 2011, Aug-08, Volume: 12

    Topics: Administration, Rectal; Africa; Antimalarials; Artemisinins; Artesunate; Bangladesh; Bias; Checklist; Double-Blind Method; Drug Administration Schedule; Evidence-Based Medicine; Humans; Intention to Treat Analysis; Malaria; Multicenter Studies as Topic; Patient Selection; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Referral and Consultation; Reproducibility of Results; Research Design; Sample Size; Severity of Illness Index; Time Factors; Treatment Outcome; World Health Organization

2011
Response to: Pre-referral rectal artesunate in severe malaria: a flawed trial.
    Trials, 2011, Aug-08, Volume: 12

    Topics: Antimalarials; Artemisinins; Artesunate; Humans; Malaria; Randomized Controlled Trials as Topic; Referral and Consultation; Research Design

2011
Treatment of imported severe malaria with artesunate instead of quinine--more evidence needed?
    Malaria journal, 2011, Sep-07, Volume: 10

    Topics: Antimalarials; Artemisinins; Artesunate; Humans; Injections, Intravenous; Malaria; Quinine

2011
Effects of artesunate on parasite recrudescence and dormancy in the rodent malaria model Plasmodium vinckei.
    PloS one, 2011, Volume: 6, Issue:10

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Disease Models, Animal; Malaria; Mice; Plasmodium

2011
Tolerability and safety of primaquine in Papua New Guinean children 1 to 10 years of age.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:4

    Topics: Aging; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Cohort Studies; Female; Glucosephosphate Dehydrogenase Deficiency; Hemoglobins; Humans; Infant; Malaria; Malaria, Falciparum; Malaria, Vivax; Male; New Guinea; Primaquine

2012
[Use of intravenous artemisinin derivatives in severe malaria].
    Anales de pediatria (Barcelona, Spain : 2003), 2012, Volume: 77, Issue:1

    Topics: Antimalarials; Artemisinins; Artesunate; Child, Preschool; Female; Humans; Injections, Intravenous; Malaria; Male; Severity of Illness Index

2012
Treatment outcome of intravenous artesunate in patients with severe malaria in the Netherlands and Belgium.
    Malaria journal, 2012, Mar-31, Volume: 11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Artesunate; Belgium; Female; Humans; Infusions, Intravenous; Malaria; Male; Middle Aged; Netherlands; Retrospective Studies; Travel; Treatment Outcome; Young Adult

2012
Assessing the consistency assumption by exploring treatment by covariate interactions in mixed treatment comparison meta-analysis: individual patient-level covariates versus aggregate trial-level covariates.
    Statistics in medicine, 2012, Dec-20, Volume: 31, Issue:29

    Topics: Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Dapsone; Drug Combinations; Ethanolamines; Fluorenes; Humans; Malaria; Meta-Analysis as Topic; Models, Statistical; Outcome Assessment, Health Care; Proguanil; Quinolines; Regression Analysis

2012
Intravenous β-artemether formulation (ARM NLC) as a superior alternative to commercial artesunate formulation.
    The Journal of antimicrobial chemotherapy, 2012, Volume: 67, Issue:11

    Topics: Administration, Intravenous; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Disease Models, Animal; Malaria; Male; Mice; Parasitemia; Plasmodium berghei; Treatment Outcome

2012
Deaths due to Plasmodium knowlesi malaria in Sabah, Malaysia: association with reporting as Plasmodium malariae and delayed parenteral artesunate.
    Malaria journal, 2012, Aug-20, Volume: 11

    Topics: Adult; Aged; Antimalarials; Artemisinins; Artesunate; Bacteremia; Diagnostic Errors; Female; Gram-Negative Bacterial Infections; Humans; Malaria; Malaysia; Male; Middle Aged; Plasmodium knowlesi; Plasmodium malariae

2012
A prospective comparative study of knowlesi, falciparum, and vivax malaria in Sabah, Malaysia: high proportion with severe disease from Plasmodium knowlesi and Plasmodium vivax but no mortality with early referral and artesunate therapy.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2013, Volume: 56, Issue:3

    Topics: Adult; Aged; Antimalarials; Artemisinins; Artesunate; Female; Humans; Malaria; Malaria, Falciparum; Malaria, Vivax; Malaysia; Male; Middle Aged; Parasitemia; Plasmodium falciparum; Plasmodium knowlesi; Plasmodium vivax; Prospective Studies; Risk Factors; Severity of Illness Index; Time Factors; Treatment Outcome; Young Adult

2013
Access to artemisinin-combination therapy (ACT) and other anti-malarials: national policy and markets in Sierra Leone.
    PloS one, 2012, Volume: 7, Issue:10

    Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Drug Costs; Geography; Health Policy; Health Services Accessibility; Humans; Malaria; Organizations, Nonprofit; Pharmacies; Poverty; Private Sector; Public Sector; Sierra Leone

2012
Effect of single nucleotide polymorphisms in cytochrome P450 isoenzyme and N-acetyltransferase 2 genes on the metabolism of artemisinin-based combination therapies in malaria patients from Cambodia and Tanzania.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:2

    Topics: Alleles; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Arylamine N-Acetyltransferase; Base Sequence; Cambodia; Cytochrome P-450 Enzyme System; Drug Combinations; Ethanolamines; Fluorenes; Gene Frequency; Humans; Isoenzymes; Malaria; Mefloquine; Pharmacogenetics; Polymorphism, Single Nucleotide; Quinolines; Sequence Analysis, DNA; Tanzania

2013
Published reports of delayed hemolytic anemia after treatment with artesunate for severe malaria--worldwide, 2010-2012.
    MMWR. Morbidity and mortality weekly report, 2013, Jan-11, Volume: 62, Issue:1

    Topics: Adolescent; Adult; Aged; Anemia, Hemolytic; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Female; Humans; Malaria; Male; Middle Aged; Retrospective Studies; Severity of Illness Index; Time Factors

2013
[The synergistic action of guanghuoxiang volatile oil and sodium artesunate against Plasmodium berghei and reversal of SA-resistant Plasmodium berghei].
    Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 2000, Volume: 18, Issue:2

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Lamiaceae; Malaria; Mice; Oils, Volatile; Phytotherapy; Plasmodium berghei; Sesquiterpenes

2000
Efficacy comparison of intravenous artelinate and artesunate in Plasmodium berghei-infected Sprague-Dawley rats.
    Parasitology, 2003, Volume: 126, Issue:Pt 4

    Topics: Animals; Artemisinins; Artesunate; Disease Models, Animal; Dose-Response Relationship, Drug; Injections, Intravenous; Malaria; Male; Parasitemia; Plant Extracts; Plasmodium berghei; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Time Factors

2003
Artesunate combinations for malaria.
    Lancet (London, England), 2004, Feb-28, Volume: 363, Issue:9410

    Topics: Antimalarials; Artemisinins; Artesunate; Cost-Benefit Analysis; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Mefloquine; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Outcome

2004
Ghana battles drug-resistant malaria with artesunate.
    Lancet (London, England), 2004, Apr-24, Volume: 363, Issue:9418

    Topics: Antimalarials; Artemisinins; Artesunate; Child, Preschool; Chloroquine; Drug Resistance; Ghana; Humans; Malaria; Sesquiterpenes

2004
Fluoroartemisinin: trifluoromethyl analogues of artemether and artesunate.
    Journal of medicinal chemistry, 2004, May-06, Volume: 47, Issue:10

    Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Drug Stability; Fluorine; Hydrolysis; Malaria; Mice; Plasmodium berghei; Plasmodium falciparum; Sesquiterpenes; Structure-Activity Relationship

2004
Fake antimalarials in Southeast Asia are a major impediment to malaria control: multinational cross-sectional survey on the prevalence of fake antimalarials.
    Tropical medicine & international health : TM & IH, 2004, Volume: 9, Issue:12

    Topics: Antimalarials; Artemisinins; Artesunate; Asia, Southeastern; Cross-Sectional Studies; Drug Labeling; Fraud; Humans; Malaria; Mefloquine; Self Medication; Sesquiterpenes

2004
A qualitative study to identify community structures for management of severe malaria: a basis for introducing rectal artesunate in the under five years children in Nakonde District of Zambia.
    BMC public health, 2005, Mar-25, Volume: 5

    Topics: Administration, Rectal; Antimalarials; Artemisinins; Artesunate; Child, Preschool; Community Health Services; Community Health Workers; Family Characteristics; Female; Focus Groups; Health Knowledge, Attitudes, Practice; Humans; Infant; Interviews as Topic; Malaria; Male; Medically Underserved Area; Parents; Patient Acceptance of Health Care; Sesquiterpenes; Suppositories; Zambia

2005
WHO combats counterfeit malaria drugs in Asia.
    BMJ (Clinical research ed.), 2005, May-07, Volume: 330, Issue:7499

    Topics: Antimalarials; Artemisinins; Artesunate; Asia; Drugs, Generic; Fraud; Humans; Malaria; Sesquiterpenes; World Health Organization

2005
Neurotoxicity due to antimalarial therapy associated with misdiagnosis of malaria.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2005, Jun-01, Volume: 40, Issue:11

    Topics: Adult; Antimalarials; Anxiety; Artemisinins; Artesunate; Ataxia; Chloroquine; Diagnostic Errors; Humans; Malaria; Male; Sesquiterpenes; Tremor

2005
New malaria combination cheaper and easier to take.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2005, Jun-07, Volume: 172, Issue:12

    Topics: Administration, Oral; Amodiaquine; Artemisinins; Artesunate; Drug Costs; Drug Therapy, Combination; Humans; Malaria; Sesquiterpenes

2005
The chemotherapy of rodent malaria. LXIII. Drug combinations to impede the selection of drug resistance, part 6: the potential value of chlorproguanil and dapsone in combination, and with the addition of artesunate.
    Annals of tropical medicine and parasitology, 2005, Volume: 99, Issue:5

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Dapsone; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Malaria; Male; Mice; Parasitemia; Plasmodium berghei; Plasmodium chabaudi; Plasmodium yoelii; Proguanil; Rodent Diseases; Sesquiterpenes

2005
Factors contributing to the development of anaemia in Plasmodium falciparum malaria: what about drug-resistant parasites?
    Journal of tropical pediatrics, 2006, Volume: 52, Issue:4

    Topics: Amodiaquine; Anemia; Animals; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Resistance; Drug Therapy, Combination; Humans; Infant; Malaria; Plasmodium falciparum; Sesquiterpenes

2006
Ex vivo perfusion of human spleens maintains clearing and processing functions.
    Blood, 2006, May-01, Volume: 107, Issue:9

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Erythrocytes; Humans; In Vitro Techniques; Malaria; Perfusion; Phagocytosis; Plasmodium falciparum; Sesquiterpenes; Spleen

2006
Improving the availability of artesunate for treatment of severe malaria.
    The Medical journal of Australia, 2006, Jan-02, Volume: 184, Issue:1

    Topics: Adult; Antimalarials; Artemisinins; Artesunate; Australia; Child; Drug Approval; Humans; Malaria; Sesquiterpenes

2006
New potential antimalarial agents: therapeutic-index evaluation of pyrroloquinazolinediamine and its prodrugs in a rat model of severe malaria.
    Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:5

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Malaria; Maximum Tolerated Dose; Parasitemia; Plasmodium berghei; Prodrugs; Pyrroles; Quinazolines; Random Allocation; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Therapeutic Equivalency

2006
Manslaughter by fake artesunate in Asia--will Africa be next?
    PLoS medicine, 2006, Volume: 3, Issue:6

    Topics: Adult; Africa; Antimalarials; Artemisinins; Artesunate; Asia; Drug and Narcotic Control; Drug Contamination; Drug Costs; Drug Packaging; Fraud; Global Health; Humans; Malaria; Male; Sesquiterpenes; Travel

2006
Intravenous artesunate recommended for patients with severe malaria: position statement from TropNetEurop.
    Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2005, Nov-24, Volume: 10, Issue:11

    Topics: Antimalarials; Artemisinins; Artesunate; Communicable Diseases, Emerging; Europe; Humans; Incidence; Injections, Intravenous; Malaria; Population Surveillance; Practice Guidelines as Topic; Sesquiterpenes; Severity of Illness Index; Treatment Outcome

2005
Role of traditional healers in the management of severe malaria among children below five years of age: the case of Kilosa and Handeni Districts, Tanzania.
    Malaria journal, 2006, Jul-18, Volume: 5

    Topics: Adult; Aged; Antimalarials; Artemisinins; Artesunate; Child, Preschool; Female; Focus Groups; Health Knowledge, Attitudes, Practice; Humans; Interviews as Topic; Malaria; Male; Medicine, African Traditional; Patient Acceptance of Health Care; Referral and Consultation; Rural Health; Sesquiterpenes; Severity of Illness Index; Tanzania

2006
Toxicity evaluation of artesunate and artelinate in Plasmodium berghei-infected and uninfected rats.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2007, Volume: 101, Issue:2

    Topics: Acute Kidney Injury; Animals; Antimalarials; Artemisinins; Artesunate; Brain Diseases; Dose-Response Relationship, Drug; Lethal Dose 50; Malaria; Male; Necrosis; Plasmodium berghei; Random Allocation; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Tail; Vascular Diseases

2007
Malaria. "One step forward, two steps back".
    East African medical journal, 2006, Volume: 83, Issue:5

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; DNA, Bacterial; Drug Therapy, Combination; Humans; Malaria; Mefloquine; Plasmodium malariae; Sesquiterpenes

2006
Characterization of counterfeit artesunate antimalarial tablets from southeast Asia.
    The American journal of tropical medicine and hygiene, 2006, Volume: 75, Issue:5

    Topics: Antimalarials; Artemisinins; Artesunate; Asia, Southeastern; Drug Labeling; Erythromycin; Humans; Malaria; Sesquiterpenes; Tablets

2006
Population pharmacokinetics of artesunate and dihydroartemisinin following intra-rectal dosing of artesunate in malaria patients.
    PLoS medicine, 2006, Volume: 3, Issue:11

    Topics: Administration, Rectal; Adolescent; Adult; Africa; Aging; Antimalarials; Artemisinins; Artesunate; Asia, Southeastern; Child; Child, Preschool; Demography; Female; Humans; Infant; Malaria; Male; Middle Aged; Parasitemia; Salvage Therapy; Sesquiterpenes; Sex Factors; Suppositories; Treatment Outcome

2006
Recognition, perceptions and treatment practices for severe malaria in rural Tanzania: implications for accessing rectal artesunate as a pre-referral.
    PloS one, 2007, Jan-17, Volume: 2, Issue:1

    Topics: Administration, Rectal; Adolescent; Adult; Aged; Antimalarials; Artemisinins; Artesunate; Child; Decision Making; Female; Humans; Interviews as Topic; Malaria; Medicine, African Traditional; Middle Aged; Pregnancy; Referral and Consultation; Tanzania; Young Adult

2007
Case 32-2006: a girl with fever after a visit to Africa.
    The New England journal of medicine, 2007, Feb-01, Volume: 356, Issue:5

    Topics: Antimalarials; Artemisinins; Artesunate; Child, Preschool; Exchange Transfusion, Whole Blood; Female; Humans; Malaria; Quinidine; Sesquiterpenes

2007
Plasmodium yoelii: influence of antimalarial treatment on acquisition of immunity in BALB/c and DBA/2 mice.
    Experimental parasitology, 2007, Volume: 116, Issue:3

    Topics: Animals; Antibodies, Protozoan; Antimalarials; Artemisinins; Artesunate; Chloroquine; Female; Immunoglobulin G; Interferon-gamma; Malaria; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Parasitemia; Plasmodium yoelii; Recurrence; Sesquiterpenes

2007
UK recommendations for severe malaria are worrying.
    BMJ (Clinical research ed.), 2007, Mar-10, Volume: 334, Issue:7592

    Topics: Antimalarials; Artemisinins; Artesunate; Drug Industry; Humans; Malaria; Sesquiterpenes

2007
Counterfeit artemisinin derivatives and Africa: update from authors.
    PLoS medicine, 2007, Mar-27, Volume: 4, Issue:3

    Topics: Africa; Antimalarials; Artemisinins; Artesunate; Asia; Drug and Narcotic Control; Drug Contamination; Drug Costs; Drug Packaging; Fraud; Humans; Malaria; Sesquiterpenes; Travel

2007
Plasmodium vivax cerebral malaria.
    Indian pediatrics, 2007, Volume: 44, Issue:6

    Topics: Animals; Artemisinins; Artesunate; Central Nervous System Protozoal Infections; Child; Humans; Malaria; Malaria, Cerebral; Male; Plasmodium vivax; Sesquiterpenes

2007
Community coverage of an antimalarial combination of artesunate and amodiaquine in Makamba Province, Burundi, nine months after its introduction.
    Malaria journal, 2007, Jul-18, Volume: 6

    Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Burundi; Child, Preschool; Community Health Services; Cross-Sectional Studies; Drug Therapy, Combination; Fever; Humans; Infant; Infant, Newborn; Malaria; Sesquiterpenes

2007
Battling the malaria iceberg with chloroquine in India.
    Malaria journal, 2007, Aug-07, Volume: 6

    Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Delivery of Health Care; Drug Combinations; Drug Resistance; Humans; India; Malaria; Preventive Health Services; Pyrimethamine; Sesquiterpenes; Socioeconomic Factors; Sulfadoxine; Time Factors

2007
[ASAQ, a breakthrough in the fight against malaria].
    Medecine tropicale : revue du Corps de sante colonial, 2007, Volume: 67, Issue:2

    Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Drug Combinations; Drug Industry; Humans; International Cooperation; Malaria; Sesquiterpenes

2007
Malaria pharmacovigilance in Africa: lessons from a pilot project in Mpumalanga Province, South Africa.
    Drug safety, 2007, Volume: 30, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Female; Humans; Infant; Malaria; Male; Middle Aged; Pilot Projects; Product Surveillance, Postmarketing; Pyrimethamine; Sesquiterpenes; South Africa; Sulfadoxine

2007
Pharmacologic advances in the global control and treatment of malaria: combination therapy and resistance.
    Clinical pharmacology and therapeutics, 2007, Volume: 82, Issue:5

    Topics: Amodiaquine; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Dapsone; Drug Design; Drug Resistance; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Global Health; Half-Life; Humans; Lumefantrine; Malaria; Mefloquine; Pregnancy; Pregnancy Complications, Infectious; Proguanil; Pyrimethamine; Quinine; Sesquiterpenes; Sulfadoxine

2007
Clinical symptoms, treatment and outcome of highlands malaria in Eldoret (2420 m a.s.l.) and comparison to malaria in hyper-immune population in endemic region of Southern Sudan.
    Neuro endocrinology letters, 2007, Volume: 28 Suppl 3

    Topics: Altitude; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Drug Therapy, Combination; Endemic Diseases; Greenhouse Effect; Humans; Kenya; Malaria; Prognosis; Sesquiterpenes; Sudan; Treatment Outcome

2007
Chorea in a 29-year-old Nigerian following antimalarial treatment with artesunate.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2008, Volume: 12, Issue:2

    Topics: Adult; Antimalarials; Artemisinins; Artesunate; Chorea; Diazepam; Humans; Malaria; Male; Muscle Relaxants, Central; Nigeria; Treatment Outcome

2008
A collaborative epidemiological investigation into the criminal fake artesunate trade in South East Asia.
    PLoS medicine, 2008, Volume: 5, Issue:2

    Topics: Artemisia; Artemisinins; Artesunate; Asia, Southeastern; Drug Contamination; Fraud; Humans; Internationality; Malaria; Sesquiterpenes

2008
Anti-malarial efficacy of pyronaridine and artesunate in combination in vitro and in vivo.
    Acta tropica, 2008, Volume: 105, Issue:3

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Drug Resistance, Multiple; Drug Therapy, Combination; In Vitro Techniques; Inhibitory Concentration 50; Malaria; Mice; Naphthyridines; Plasmodium; Plasmodium berghei; Plasmodium falciparum; Sesquiterpenes; Treatment Outcome

2008
Disease and drug interactions: treating malaria with artesunate plus amodiaquine in patients also receiving treatment for concomitant HIV infection.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2008, Apr-01, Volume: 46, Issue:7

    Topics: Amodiaquine; Anti-HIV Agents; Antimalarials; Artemisinins; Artesunate; Drug Interactions; Drug Therapy, Combination; HIV Infections; Humans; Malaria; Neutropenia; Sesquiterpenes

2008
IV artesunate for severe malaria.
    The Medical letter on drugs and therapeutics, 2008, May-19, Volume: 50, Issue:1286

    Topics: Antimalarials; Artemisinins; Artesunate; Humans; Infusions, Intravenous; Malaria; Sesquiterpenes

2008
Clinical studies on treatment of cerebral malaria with qinghaosu and its derivatives.
    Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 1982, Volume: 2, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Brain Diseases; Child; Child, Preschool; Female; Humans; Malaria; Male; Middle Aged; Plasmodium falciparum; Sesquiterpenes

1982
The antimalarial and toxic effect of artesunate on animal models.
    Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 1982, Volume: 2, Issue:2

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Dogs; Female; Guinea Pigs; Macaca mulatta; Malaria; Male; Mice; Plasmodium; Plasmodium berghei; Rabbits; Sesquiterpenes

1982
Artemisinin: current status.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1994, Volume: 88 Suppl 1

    Topics: Antimalarials; Antiprotozoal Agents; Artemisinins; Artesunate; Drugs, Chinese Herbal; Humans; Malaria; Sesquiterpenes

1994
Comparison of in vivo and in vitro antimalarial activity of artemisinin, dihydroartemisinin and sodium artesunate in the Plasmodium berghei-rodent model.
    International journal for parasitology, 1994, Volume: 24, Issue:4

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Malaria; Mice; Plasmodium berghei; Rats; Rats, Wistar; Sesquiterpenes

1994
The iron environment in heme and heme-antimalarial complexes of pharmacological interest.
    Journal of inorganic biochemistry, 1996, Volume: 63, Issue:1

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Heme; Hemeproteins; Hemin; Humans; Iron; Malaria; Quinine; Sesquiterpenes; Spectroscopy, Mossbauer

1996
Effects of artesunate on immune function in mice.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1995, Volume: 16, Issue:5

    Topics: Adjuvants, Immunologic; Animals; Antimalarials; Artemisinins; Artesunate; Complement C3; Female; Hemolysin Proteins; Immunoglobulin G; Lymphocyte Activation; Malaria; Male; Mice; Mice, Inbred ICR; Phagocytosis; Plasmodium berghei; Sesquiterpenes

1995
The chemotherapy of rodent malaria. LIII. 'Fenozan B07' (Fenozan-50F), a difluorinated 3,3'-spirocyclopentane 1,2,4-trioxane: comparison with some compounds of the artemisinin series.
    Annals of tropical medicine and parasitology, 1997, Volume: 91, Issue:1

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Drug Synergism; Malaria; Male; Mice; Parasitemia; Peroxides; Plasmodium; Plasmodium berghei; Plasmodium yoelii; Sesquiterpenes; Spiro Compounds

1997
Plasma levels of the interleukin-6 cytokine family in persons with severe Plasmodium falciparum malaria.
    The Journal of infectious diseases, 1999, Volume: 179, Issue:3

    Topics: Acute Kidney Injury; Adolescent; Adult; Animals; Antimalarials; Artemisinins; Artesunate; Biomarkers; Ciliary Neurotrophic Factor; Female; Humans; Interleukin-6; Malaria; Malaria, Cerebral; Malaria, Falciparum; Male; Middle Aged; Nerve Growth Factors; Nerve Tissue Proteins; Plasmodium falciparum; Receptors, Interleukin-6; Reference Values; Sesquiterpenes

1999
What are the World Health Organization's strategies for meeting regulatory requirements? A case study of artesunate.
    Medecine tropicale : revue du Corps de sante colonial, 1998, Volume: 58, Issue:3 Suppl

    Topics: Administration, Rectal; Antimalarials; Artemisinins; Artesunate; Chemistry, Pharmaceutical; Drug Approval; Europe; Evidence-Based Medicine; Health Services Needs and Demand; Humans; Malaria; Public Health; Registries; Sesquiterpenes; Time Factors; United States; World Health Organization

1998
Imported malaria: successful treatment of 31 patients in the era of chloroquine resistance.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 1999, Volume: 98, Issue:10

    Topics: Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Child; Chloroquine; Drug Resistance; Female; Humans; Malaria; Male; Middle Aged; Primaquine; Quinine; Retrospective Studies; Sesquiterpenes; Travel

1999
The chemotherapy of rodent malaria. LVI. Studies on the development of resistance to natural and synthetic endoperoxides.
    Annals of tropical medicine and parasitology, 1999, Volume: 93, Issue:4

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Drug Resistance; Malaria; Male; Mice; Peroxides; Plasmodium berghei; Plasmodium yoelii; Sesquiterpenes

1999
Schizontocidal effects of oral artesunate on Plasmodium berghei in mice and P knowlesi in monkeys.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1999, Volume: 20, Issue:8

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Erythrocytes; Female; Macaca mulatta; Malaria; Male; Mice; Plasmodium berghei; Plasmodium knowlesi; Sesquiterpenes

1999
Fake antimalaria drugs in Cambodia.
    Lancet (London, England), 2001, Mar-17, Volume: 357, Issue:9259

    Topics: Antimalarials; Artemisinins; Artesunate; Cambodia; Humans; Malaria; Mefloquine; Product Surveillance, Postmarketing; Sesquiterpenes

2001
Potent antimalarial activities of polyether antibiotic, X-206.
    The Journal of antibiotics, 2001, Volume: 54, Issue:8

    Topics: Actinomycetales; Animals; Anti-Bacterial Agents; Antimalarials; Artemether; Artemisinins; Artesunate; Cell Death; Cell Line; Chloroquine; Drug Resistance; Embryo, Mammalian; Embryo, Nonmammalian; Ethers, Cyclic; Humans; Malaria; Mice; Molecular Structure; Plasmodium berghei; Plasmodium falciparum; Pyrimethamine; Quinine; Sesquiterpenes

2001
Histopathological changes of Macaca mulatta infected with Plasmodium knowlesi.
    Chinese medical journal, 2001, Volume: 114, Issue:10

    Topics: Animals; Artemisinins; Artesunate; Macaca mulatta; Malaria; Monkey Diseases; Plasmodium knowlesi; Quinolines; Sesquiterpenes; Suppositories

2001
Mathematical modelling of malaria chemotherapy: combining artesunate and mefloquine.
    Parasitology, 2002, Volume: 124, Issue:Pt 1

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Computer Simulation; Drug Therapy, Combination; Humans; Malaria; Mefloquine; Models, Biological; Parasitemia; Plasmodium; Sesquiterpenes

2002
Impact of large-scale rectal artesunate deployment in the emergency management of malaria.
    Releve epidemiologique hebdomadaire, 2002, Mar-22, Volume: 77, Issue:12

    Topics: Administration, Rectal; Antimalarials; Artemisinins; Artesunate; Clinical Trials as Topic; Emergency Treatment; Female; Humans; International Cooperation; Malaria; Male; Patient Selection; Sesquiterpenes; Severity of Illness Index; World Health Organization

2002
[Effect of artesunate transdermal preparation on Plasmodium cynomolgi].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1990, Volume: 25, Issue:3

    Topics: Administration, Cutaneous; Animals; Antimalarials; Artemisinins; Artesunate; Azepines; Drug Synergism; Macaca mulatta; Malaria; Male; Plasmodium; Sesquiterpenes

1990
Decreased sensitivity of artesunate and chloroquine of Plasmodium falciparum infecting hemoglobin H and/or hemoglobin constant spring erythrocytes.
    The Journal of clinical investigation, 1989, Volume: 83, Issue:2

    Topics: Animals; Artemisinins; Artesunate; Chloroquine; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Erythrocytes; Hemoglobin H; Hemoglobins, Abnormal; Humans; Malaria; Plasmodium falciparum; Sesquiterpenes

1989
[Clinical observations on 100 cases of malignant malaria treated with artesunate tablets].
    Zhonghua yi xue za zhi, 1989, Volume: 69, Issue:9

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Humans; Malaria; Plasmodium falciparum; Sesquiterpenes; Tablets

1989
Experimental studies on the antimalarial activity estimation by artesunate and artemether preparations per skin absorption.
    Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 1988, Volume: 8, Issue:4

    Topics: Administration, Cutaneous; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Female; Malaria; Male; Mice; Plasmodium berghei; Sesquiterpenes; Skin Absorption

1988
[Clinical study on the treatment of malaria with artemether and artesunate].
    Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 1988, Volume: 6, Issue:1

    Topics: Adolescent; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Child; Child, Preschool; Humans; Malaria; Plasmodium falciparum; Plasmodium vivax; Pyrans; Recurrence; Sesquiterpenes

1988
[Development of a qinghaosu-resistant line of Plasmodium berghei ANKA and N strain].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1986, Volume: 21, Issue:11

    Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Drug Resistance, Microbial; Malaria; Male; Mice; Plasmodium berghei; Primaquine; Pyrans; Sesquiterpenes

1986
The chemotherapy of rodent malaria, XL. The action of artemisinin and related sesquiterpenes.
    Annals of tropical medicine and parasitology, 1986, Volume: 80, Issue:5

    Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Drug Resistance; Malaria; Male; Mice; Pigments, Biological; Plasmodium berghei; Pyrans; Sesquiterpenes

1986
Antimalarial agents. III. Mechanism of action of artesunate against Plasmodium berghei infection.
    Chemical & pharmaceutical bulletin, 1987, Volume: 35, Issue:5

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Malaria; Male; Mice; Mice, Inbred Strains; Plasmodium berghei; Sesquiterpenes

1987
Experimental studies on the effect of artesunate sustained released tablet on Plasmodium cynomolgi.
    Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 1987, Volume: 7, Issue:4

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Delayed-Action Preparations; Female; Macaca mulatta; Malaria; Male; Sesquiterpenes; Tablets

1987
[Development of a piperaquine-resistant line of Plasmodium berghei K 173 strain].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1985, Volume: 20, Issue:6

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Malaria; Male; Mefloquine; Mice; Plasmodium berghei; Quinolines; Sesquiterpenes

1985