Compounds > artesunic acid
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artesunic acid and Cytomegalovirus

artesunic acid has been researched along with Cytomegalovirus in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (19.05)29.6817
2010's10 (47.62)24.3611
2020's7 (33.33)2.80

Authors

AuthorsStudies
Alain, S; Andouard, D; Bernardaud, L; Duroux, JL; Fagnère, C; Gueye, R; Hantz, S; Liagre, B; Pouget, C1
Bhat, V; Biswas, S; Bonda, A; Chichra, A; Gokarn, A; Jindal, N; Khattry, N; Kumar, S; Mirgh, S; Nayak, L; Prayag, P; Punatar, S; Saroha, M; Shenoy, R; Toshniwal, A; Tripathi, R1
Alain, S; Andouard, D; Chianea, T; El Hamel, C; Hantz, S; Jacquet, C; Marschall, M; Tsogoeva, SB1
Bertzbach, LD; Fröhlich, T; Hahn, F; Herrmann, L; Kaufer, BB; Marschall, M; Müller, R; Tannig, P; Tsogoeva, SB; Wangen, C; Wild, M1
Adrait, A; Capci, A; Couté, Y; Grau, B; Hahn, F; Herrmann, L; Marschall, M; Niesar, A; Tsogoeva, SB; Wangen, C; Wild, M1
Ackermann, L; Grau, B; Hahn, F; Herrmann, L; Lorion, MM; Marschall, M; Niesar, A; Schütz, M; Tsogoeva, SB; Wild, M1
Arav-Boger, R; Ghosh, AK; Kapoor, A; Lee, H; Mazzone, J; Mukhopadhyay, R; Posner, GH; Roy, S; Zhu, F1
Bertzbach, LD; Frank, T; Fröhlich, T; Hahn, F; Kaufer, BB; Kohrt, S; Marschall, M; Stamminger, T; Tsogoeva, SB1
Bunts, L; Casper, C; Dorsey, G; Gantt, S; Huang, ML; Magaret, A; Rosenthal, PJ; Selke, S; Wald, A1
Desbordes, M; Flobinus, A; Labrosse, B; Mazeron, MC; Schnepf, N; Simon, F; Taudon, N1
Alain, S; Brion, JP; Epaulard, O; Germi, R; Lupo, J; Malvezzi, P; Mariette, C; Morand, P; Saint Raymond, C; Thiebaut, A1
Bahsi, H; Efferth, T; Einsiedel, J; Fröhlich, T; Gmeiner, P; Godl, K; Hutterer, C; Kadioglu, O; Marschall, M; Milbradt, J; Niemann, I; Reiter, C; Stamminger, T; Tsogoeva, SB; Vogel, N; Wagner, S; Wandinger, S; Zeitträger, I1
Boivin, G; Drouot, E; Piret, J1
Efferth, T; Marin, JJ; Marschall, M; Romero, MR; Stamminger, T; Wolf, DG1
Corvo, J; Mazeron, MC; Pors, MJ; Schnepf, N1
John, GT; Lau, PK; Ratanjee, SK; Woods, ML1
Caplan, O; Chou, S; Efferth, T; Marschall, M; Nagler, A; Neumann, AU; Resnick, IB; Rose, J; Shimoni, A; Stamminger, T; Wolf, DG1
Auerochs, S; Chou, S; Marousek, G; Marschall, M; Milbradt, J; Stamminger, T1
Auerochs, S; Bruggeman, CA; Efferth, T; Kalmer, M; Kaptein, SJ; Leis, M; Marschall, M; Rechter, S; Stamminger, T; Vink, C1
Caplan, O; Chou, S; Efferth, T; Lurain, NS; Marschall, M; Neumann, AU; Resnick, IB; Saleh, N; Shapira, MY; Stamminger, T; Wolf, DG1
Efferth, T; Hauber, I; Huang, ES; Huong, SM; Kronschnabl, M; Marschall, M; Olbrich, A; Stamminger, T; Wang, X1

Reviews

1 review(s) available for artesunic acid and Cytomegalovirus

ArticleYear
The antiviral activities of artemisinin and artesunate.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2008, Sep-15, Volume: 47, Issue:6

    Topics: Antiviral Agents; Artemisinins; Artesunate; Cytomegalovirus; Hepacivirus; Herpesviridae; HIV-1; Humans

2008

Trials

1 trial(s) available for artesunic acid and Cytomegalovirus

ArticleYear
An artesunate-containing antimalarial treatment regimen did not suppress cytomegalovirus viremia.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2013, Volume: 58, Issue:1

    Topics: Adolescent; Antimalarials; Antiviral Agents; Artemisinins; Artesunate; Child; Child, Preschool; Cytomegalovirus; Cytomegalovirus Infections; DNA, Viral; Drug Therapy, Combination; Female; Humans; Infant; Malaria; Male; Real-Time Polymerase Chain Reaction; Treatment Outcome; Uganda; Viremia

2013

Other Studies

19 other study(ies) available for artesunic acid and Cytomegalovirus

ArticleYear
Impact of new cyclooxygenase 2 inhibitors on human cytomegalovirus replication in vitro.
    Antiviral therapy, 2021, Volume: 26, Issue:6-8

    Topics: Antiviral Agents; Artesunate; Chalcone; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cytomegalovirus; Dinoprostone; Ganciclovir; Humans

2021
Efficacy of artesunate for treatment of cytomegalovirus reactivation post allogeneic haematopoietic stem cell transplants.
    Bone marrow transplantation, 2023, Volume: 58, Issue:2

    Topics: Artesunate; Cytomegalovirus; Cytomegalovirus Infections; Hematopoietic Stem Cell Transplantation; Humans; Virus Activation

2023
A highly potent trimeric derivative of artesunate shows promising treatment profiles in experimental models for congenital HCMV infection in vitro and ex vivo.
    Antiviral research, 2020, Volume: 175

    Topics: Antiviral Agents; Artesunate; Cell Line; Cytomegalovirus; Cytomegalovirus Infections; Epithelial Cells; Female; Fibroblasts; Humans; Lung; Organ Culture Techniques; Placenta; Pregnancy; Virus Replication

2020
The trimeric artesunate derivative TF27 exerts strong anti-cytomegaloviral efficacy: Focus on prophylactic efficacy and oral treatment of immunocompetent mice.
    Antiviral research, 2020, Volume: 178

    Topics: Administration, Oral; Animals; Antiviral Agents; Artesunate; Cells, Cultured; Chick Embryo; Cytomegalovirus; Cytomegalovirus Infections; Drugs, Investigational; Humans; Marek Disease; Mice; Virus Replication

2020
Target verification of artesunate-related antiviral drugs: Assessing the role of mitochondrial and regulatory proteins by click chemistry and fluorescence labeling.
    Antiviral research, 2020, Volume: 180

    Topics: Antiviral Agents; Artesunate; Cell Line; Cells, Cultured; Click Chemistry; Cytomegalovirus; Fibroblasts; Foreskin; Green Fluorescent Proteins; Humans; Male; Microscopy, Confocal; Mitochondria; Mitochondrial Proteins; Optical Imaging; Proteomics; Signal Transduction; Virus Replication

2020
The Artemisinin-Derived Autofluorescent Compound BG95 Exerts Strong Anticytomegaloviral Activity Based on a Mitochondrial Targeting Mechanism.
    International journal of molecular sciences, 2020, Aug-04, Volume: 21, Issue:15

    Topics: Antiviral Agents; Artemisinins; Artesunate; Cytomegalovirus; Cytomegalovirus Infections; Drug Resistance, Viral; Fluorescent Dyes; Humans; Mitochondria; Viral Proteins; Virus Replication

2020
Artemisinins target the intermediate filament protein vimentin for human cytomegalovirus inhibition.
    The Journal of biological chemistry, 2020, 10-30, Volume: 295, Issue:44

    Topics: Antiviral Agents; Artemisinins; Artesunate; Binding Sites; Calpain; Cell Cycle; Cells, Cultured; Cytomegalovirus; Cytomegalovirus Infections; Drug Repositioning; Humans; Mass Spectrometry; Phosphorylation; Proteasome Endopeptidase Complex; Vimentin; Virus Replication; Withanolides

2020
Artesunate-derived monomeric, dimeric and trimeric experimental drugs - Their unique mechanistic basis and pronounced antiherpesviral activity.
    Antiviral research, 2018, Volume: 152

    Topics: Antiviral Agents; Artesunate; Cytomegalovirus; Cytomegalovirus Infections; Dimerization; Drugs, Investigational; Humans; Microbial Sensitivity Tests; NF-kappa B; Viral Proteins; Virus Replication

2018
Stability and antiviral activity against human cytomegalovirus of artemisinin derivatives.
    The Journal of antimicrobial chemotherapy, 2014, Volume: 69, Issue:1

    Topics: Antiviral Agents; Artemisinins; Artesunate; Biotransformation; Culture Media; Cytomegalovirus; Humans; Inhibitory Concentration 50; Microbial Sensitivity Tests

2014
Success and failure of artesunate treatment in five transplant recipients with disease caused by drug-resistant cytomegalovirus.
    Antiviral research, 2014, Volume: 101

    Topics: Antiviral Agents; Artemisinins; Artesunate; Cytomegalovirus; Cytomegalovirus Infections; Drug Resistance, Viral; Female; Hematopoietic Stem Cell Transplantation; Humans; Male; Middle Aged; Organ Transplantation; Transplantation; Treatment Outcome; Viral Load

2014
The broad-spectrum antiinfective drug artesunate interferes with the canonical nuclear factor kappa B (NF-κB) pathway by targeting RelA/p65.
    Antiviral research, 2015, Volume: 124

    Topics: Antiviral Agents; Artemisinins; Artesunate; Cyclic AMP Response Element-Binding Protein; Cytomegalovirus; Drug Resistance, Viral; HEK293 Cells; Herpesviridae; Humans; Mutation; NF-kappa B; Signal Transduction; Transcription Factor RelA; Transcriptional Activation; Up-Regulation

2015
Artesunate demonstrates in vitro synergism with several antiviral agents against human cytomegalovirus.
    Antiviral therapy, 2016, Volume: 21, Issue:6

    Topics: Antiviral Agents; Artemisinins; Artesunate; Cell Line; Cytomegalovirus; Cytomegalovirus Infections; Drug Resistance, Viral; Drug Synergism; Humans; In Vitro Techniques; Microbial Sensitivity Tests; Viral Proteins; Virus Replication

2016
Antiviral activity of ganciclovir and artesunate towards human cytomegalovirus in astrocytoma cells.
    Antiviral research, 2011, Volume: 89, Issue:2

    Topics: Antiviral Agents; Artemisinins; Artesunate; Astrocytes; Cell Line, Tumor; Cytomegalovirus; Fibroblasts; Ganciclovir; Humans; Inhibitory Concentration 50; Microbial Sensitivity Tests

2011
Artesunate is ineffective in controlling valganciclovir-resistant cytomegalovirus infection.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2011, Jan-15, Volume: 52, Issue:2

    Topics: Antiviral Agents; Artemisinins; Artesunate; Cytomegalovirus; Cytomegalovirus Infections; Drug Resistance, Viral; Ganciclovir; Humans; Treatment Failure; Valganciclovir

2011
Human cytomegalovirus kinetics following institution of artesunate after hematopoietic stem cell transplantation.
    Antiviral research, 2011, Volume: 90, Issue:3

    Topics: Adult; Aged; Antiviral Agents; Artemisinins; Artesunate; Child; Cytomegalovirus; Cytomegalovirus Infections; Female; Hematopoietic Stem Cell Transplantation; Humans; Kinetics; Male; Middle Aged; Viral Load

2011
The unique antiviral activity of artesunate is broadly effective against human cytomegaloviruses including therapy-resistant mutants.
    Antiviral research, 2011, Volume: 92, Issue:2

    Topics: Antiviral Agents; Artemisinins; Artesunate; Benzimidazoles; Cell Line; Cytomegalovirus; Drug Synergism; Humans; Inhibitory Concentration 50; Microbial Sensitivity Tests; Ribonucleosides; Virus Replication

2011
The anti-malaria drug artesunate inhibits replication of cytomegalovirus in vitro and in vivo.
    Antiviral research, 2006, Volume: 69, Issue:2

    Topics: Animals; Antimalarials; Antiviral Agents; Artemisinins; Artesunate; Cells, Cultured; Cytomegalovirus; Cytomegalovirus Infections; Drug Therapy, Combination; Ferrous Compounds; Fibroblasts; Herpesviridae Infections; Humans; Immunocompromised Host; Male; Muromegalovirus; Rats; Rats, Inbred Lew; Sesquiterpenes; Specific Pathogen-Free Organisms; Transferrin; Virus Replication

2006
Artesunate as a potent antiviral agent in a patient with late drug-resistant cytomegalovirus infection after hematopoietic stem cell transplantation.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2008, May-01, Volume: 46, Issue:9

    Topics: Antiviral Agents; Artemisinins; Artesunate; Child; Cytomegalovirus; Cytomegalovirus Infections; Drug Resistance, Viral; Foscarnet; Hematopoietic Stem Cell Transplantation; Humans; Male; Treatment Outcome

2008
Antiviral activity of artesunate towards wild-type, recombinant, and ganciclovir-resistant human cytomegaloviruses.
    Journal of molecular medicine (Berlin, Germany), 2002, Volume: 80, Issue:4

    Topics: Antiviral Agents; Artemisinins; Artesunate; Cells, Cultured; Cytomegalovirus; DNA, Viral; Drug Resistance, Viral; Ganciclovir; Green Fluorescent Proteins; Humans; Luminescent Proteins; Microbial Sensitivity Tests; NF-kappa B; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Ribosomal Protein S6 Kinases; Sesquiterpenes; Simplexvirus; Sp1 Transcription Factor; Viral Plaque Assay; Virus Replication

2002