Page last updated: 2024-08-26

artesunic acid and Colorectal Cancer

artesunic acid has been researched along with Colorectal Cancer in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (22.22)29.6817
2010's5 (55.56)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Chen, Y; Du, B; Feng, Q; Gan, S; Huang, Q; Huang, Z; Liu, Z; Lu, L; Qi, X; Wang, Y; Zhang, R; Zhuang, X1
Chen, Y; Du, Q; Gong, Z; Pan, D; Peng, J; Sun, R; Wang, Q; Zhou, J1
Das, P; Kumar, VL; Verma, S2
Cui, C; Feng, H; Feng, Z; Fu, J; Fu, Z; Han, Z; Liu, J; Shi, X; Tong, H; Wang, Y1
Picot, S1
Cowan, M; Efferth, T; Finlayson, C; Ganapathi, S; Jansen, H; Kovacsevics, H; Kremsner, PG; Krishna, S; Kumar, D; Saeed, ME; Ster, IC1
Li, LN; Sun, ZX; Tian, ZY; Wang, L; Yuan, SJ; Zhang, HD1
Li, LN; Sun, ZX; Wang, L; Yang, DX; Yuan, SJ; Zhang, HD1

Trials

1 trial(s) available for artesunic acid and Colorectal Cancer

ArticleYear
A Randomised, Double Blind, Placebo-Controlled Pilot Study of Oral Artesunate Therapy for Colorectal Cancer.
    EBioMedicine, 2015, Volume: 2, Issue:1

    Topics: Administration, Oral; Aged; Artemisinins; Artesunate; Biomarkers, Tumor; Carcinoembryonic Antigen; Colorectal Neoplasms; Demography; Double-Blind Method; Female; Humans; Immunohistochemistry; Ki-67 Antigen; Male; Pilot Projects; Placebos; Staining and Labeling; Survival Analysis; Treatment Outcome

2015

Other Studies

8 other study(ies) available for artesunic acid and Colorectal Cancer

ArticleYear
Artesunate Inhibits the Cell Growth in Colorectal Cancer by Promoting ROS-Dependent Cell Senescence and Autophagy.
    Cells, 2022, 08-09, Volume: 11, Issue:16

    Topics: Animals; Apoptosis; Artesunate; Autophagy; Cell Line, Tumor; Cell Proliferation; Cellular Senescence; Colorectal Neoplasms; Endoribonucleases; Mice; Protein Serine-Threonine Kinases; Reactive Oxygen Species

2022
Dual-targeting of artesunate and chloroquine to tumor cells and tumor-associated macrophages by a biomimetic PLGA nanoparticle for colorectal cancer treatment.
    International journal of biological macromolecules, 2023, Jul-31, Volume: 244

    Topics: Animals; Artesunate; Biomimetics; Cell Line, Tumor; Chloroquine; Colorectal Neoplasms; Mice; Nanoparticles; Polylactic Acid-Polyglycolic Acid Copolymer; Tumor Microenvironment; Tumor-Associated Macrophages

2023
Artesunate suppresses inflammation and oxidative stress in a rat model of colorectal cancer.
    Drug development research, 2019, Volume: 80, Issue:8

    Topics: 1,2-Dimethylhydrazine; Administration, Oral; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Artesunate; Aspirin; Colorectal Neoplasms; Cyclooxygenase 2; Down-Regulation; Drug Administration Schedule; Interleukin-1beta; Male; Neoplasms, Experimental; NF-kappa B; Nitric Oxide Synthase Type II; Oxidative Stress; Rats; Treatment Outcome

2019
Chemoprevention by artesunate in a preclinical model of colorectal cancer involves down regulation of β-catenin, suppression of angiogenesis, cellular proliferation and induction of apoptosis.
    Chemico-biological interactions, 2017, Dec-25, Volume: 278

    Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Animals; Apoptosis; Artemisinins; Artesunate; Aspirin; bcl-2-Associated X Protein; beta Catenin; Cell Proliferation; Colorectal Neoplasms; DNA Fragmentation; Down-Regulation; Male; Matrix Metalloproteinase 9; Neovascularization, Pathologic; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Vascular Endothelial Growth Factor A

2017
Artesunate down-regulates immunosuppression from colorectal cancer Colon26 and RKO cells in vitro by decreasing transforming growth factor β1 and interleukin-10.
    International immunopharmacology, 2015, Volume: 27, Issue:1

    Topics: Animals; Artemisinins; Artesunate; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cytokines; Cytotoxicity, Immunologic; Dinoprostone; Humans; Immunosuppression Therapy; Interleukin-10; Killer Cells, Natural; Lymphocyte Activation; Mice; Transforming Growth Factor beta1; Tumor Escape; Vascular Endothelial Growth Factor A

2015
The Other Face of Artesunate: Southern Drug to Treat Northern Diseases.
    EBioMedicine, 2015, Volume: 2, Issue:1

    Topics: Artemisinins; Artesunate; Colorectal Neoplasms; Female; Humans; Male

2015
Artesunate attenuates the growth of human colorectal carcinoma and inhibits hyperactive Wnt/beta-catenin pathway.
    International journal of cancer, 2007, Sep-15, Volume: 121, Issue:6

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Artemisinins; Artesunate; beta Catenin; Blotting, Western; Cell Proliferation; Colorectal Neoplasms; Flow Cytometry; Fluorescent Antibody Technique; Gene Expression; Humans; Immunohistochemistry; Male; Mice; Middle Aged; Reverse Transcriptase Polymerase Chain Reaction; Sesquiterpenes; Signal Transduction; Wnt Proteins; Xenograft Model Antitumor Assays

2007
Differential sensitivity of colorectal cancer cell lines to artesunate is associated with expression of beta-catenin and E-cadherin.
    European journal of pharmacology, 2008, Jun-24, Volume: 588, Issue:1

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Artemisinins; Artesunate; beta Catenin; Blotting, Western; Cadherins; Cell Cycle; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Female; Flow Cytometry; Fluorescent Antibody Technique, Indirect; Humans; Immunohistochemistry; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Neoplasm Proteins; Subcellular Fractions

2008