Page last updated: 2024-08-26

artesunic acid and Cerebral Malaria

artesunic acid has been researched along with Cerebral Malaria in 65 studies

Research

Studies (65)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	10 (15.38)	18.2507
2000's	15 (23.08)	29.6817
2010's	29 (44.62)	24.3611
2020's	11 (16.92)	2.80

Authors

Authors	Studies
Chen, X; Guenther, G; Izem, R; Postels, D; Saidi, AM; Seydel, K	1
Alao, MA; Asinobi, AO; Gbadero, DA; Ibrahim, OR; Nna, EO; Okoye, IJ; Orimadegun, AE; Oyenuga, AO	1
Echendu, ST; Edokwe, ES; Iloh, KK; Nri-Ezedi, CA; Nwaneli, EI; Okeke, KN	1
Amoh, G; Amuzu, DSY; Andoh, NE; Ansong, M; Hirst, J; Nyaaba, N; Ordóñez-Mena, JM	1
Deng, C; Guo, W; Guo, X; Huang, X; Li, C; Pan, Z; Song, J; Tang, Y; Wang, Q; Wu, Z; Xu, Q; Yuan, Y; Zhang, H; Zou, Y	1
Bienvenu, AL; Bin Sa'id, I; Bonnot, G; Coudert, A; Farias, G; Fieux, M; Fromentin, E; Hauchard, N; Kouakou, YI; Lavoignat, A; Millet, A; Omorou, R; Picot, S	1
Chaniad, P; Konyanee, A; Phuwajaroanpong, A; Plirat, W; Punsawad, C; Septama, AW; Viriyavejakul, P	1
Chen, L; Chen, Y; Guo, Y; Jiang, X; Li, K; Li, Y; Liu, H; Qu, S; Weng, X; Yang, T; Zheng, Z; Zhu, X	1
Agbo, CP; Attama, AA; McConville, C; Ofokansi, KC; Ugwuanyi, TC; Ugwuoke, WI	1
Dzikowski, R; Golenser, J; Mäder, K; Simantov, K; Zech, J	1
Chen, L; Deng, S; Li, Y; Liu, H; Qu, S; Wang, X; Yang, Y; Zhang, Y; Zheng, Z; Zhu, X	1
Cao, Y; Chen, G; Cui, L; Du, Y; Yu, C; Zhang, X	1
Kimani, FT; Kirira, PG; Magoma, GN; Malala, BJ; Muregi, FW; Odhiambo, OC; Wamakima, HN	1
Besla, R; Davies, M; Elphinstone, RE; Hausladen, A; Husain, M; Kain, KC; Lu, Z; Robbins, CS; Shikatani, EA; Stamler, JS	1
Carter, C; Mukonka, PS	1
Balani, B; Feldman, J; Hewitt, K; Parrish, A; Procopio, G; Zodda, D	1
Chen, LN; Guo, Y; Jiang, XH; Li, K; Li, YJ; Yang, T; Zheng, XJ; Zheng, ZY; Zhu, XX	1
Carvalho, LJM; Daniel-Ribeiro, CT; Frangos, JA; Moreira, AS; Ong, PK	1
Effa, EE; Esu, EB; Meremikwu, MM; Opie, ON	1
DellaValle, B; Hempel, C; Kurtzhals, JA; Staalsoe, T	1
Carvalho, LJ; Clemmer, L; Frangos, JA; Martins, YC; Ong, PK; Orjuela-Sánchez, P; Zanini, GM	1
Combes, V; El-Assaad, F; Grau, GE; Jambou, R	1
Brant, F; Campos, AC; Cisalpino, D; Machado, FS; Miranda, AS; Rachid, MA; Rocha, NP; Rodrigues, DH; Souza, DG; Teixeira, AL	1
Adhikari, B; Krudsood, S; Tangpukdee, N; Wilairatana, P	1
Agrawal, B; Kumar, M; Kumar, S; Kumari, R	1
Basilico, N; Bosisio, E; Colombo, E; Dell'Agli, M; Haynes, RK; Magenta, D; Parapini, S; Sangiovanni, E; Taramelli, D	1
Effa, EE; Esu, E; Meremikwu, MM; Opie, ON; Uwaoma, A	1
Bienvenu, AL; Bonnot, G; Bringer, C; Fourier, A; Gagnieu, MC; Lavoignat, A; Marijon, A; Picot, S	1
Brant, F; Campos, AC; Machado, FS; Miranda, AS; Teixeira, AL	1
Allister, LM; Brown, DF; Miller, ES; Schultz, ML	1
Bertinaria, M; Carvalho, LJ; Frangos, JA; Fruttero, R; Gasco, A; Guglielmo, S; Hofer, A; Marini, E; Martins, YC; Orjuela-Sanchez, P; Zanini, GM	1
Bhatt, AN; Dhunputh, P; Gupta, H; Satyamoorthy, K; Umakanth, S	1
Kandasamy, D; Lodha, R; Rathia, SK; Sankar, J	1
Amireh, S; Guron, G; Shaaban, H	1
Conroy, AL; Crowley, V; Hawkes, M; Hay, JG; Higgins, SJ; Kain, KC; Liles, WC; Opoka, RO; Purcell, LA; Quaggin, SE; Silver, KL; Thurston, G; Tran, V	1
Bienvenu, AL; Picot, S	1
Chakrabartty, S; Patra, VS; Ranjan, R; Thapa, R	1
Ohnishi, K	1
Alexander, ND; Aziz, N; Conway, DJ; de Souza, JB; Foxwell, BM; Jasseh, M; Kaur, H; Kaye, PM; Muangnoicharoen, S; Okomo, U; Owens, BM; Sumariwalla, PF; Tracey, KJ; Ulloa, L; Walther, M; Ward, SA; Warhurst, DC	1
Carvalho, LJ; Clemmer, L; Frangos, JA; Martins, YC; Zanini, GM	1
Cserti-Gazdewich, C; Dhabangi, A; Finney, CA; Hawkes, CA; Kain, DC; Kain, KC; Liles, WC; Musoke, C; Oravecz, T	1
Francis, RC; Kain, DC; Kain, KC; Kim, H; Liles, WC; Lu, Z; Miller, C; Serghides, L; Zapol, WM	1
Krishna, S	1
Agus, C; Batty, KT; Binh, TQ; Chiswell, GM; Davis, TM; Ilett, KF; Phuöng, HL; Phuong, VD	1
Folb, P; Gumede, B; Ryffel, B	1
Havlik, I; Kaneko, Y; Kozbor, D; Krudsood, S; Looareesuwan, S; Thuma, PE; Vannaphan, S; Watanabe, N; Wilairatana, P	1
Attanath, P; Chaivisuth, A; Chanthavanich, P; Na-Bangchang, K; Pengsaa, K; Pojjaroen-Anant, C; Sabchareon, A; Sirivichayakul, C; Thaiarporn, I; Wisetsing, P; Wongsuwan, A	1
Chang, SC; Chen, YC; Fang, CT; Kuo, PH; Sun, HY; Wang, JT	1
Göbels, K; Häussinger, D; Koch, S; Oette, M; Richter, J	1
Kundu, R; Patra, V; Thapa, R	1
Bienvenu, AL; Ferrandiz, J; Kaiser, K; Latour, C; Picot, S	1
Brown, AE; Corcoran, KD; Kyle, DE; Maeno, Y; Ngampochjana, M; Ockenhouse, CF; Smith, CD; Tegoshi, T; Toyoshima, T; Webster, HK	1
Fu, LC; Guo, XB; Jian, HX; Li, GQ; Wang, XH	1
Graninger, W; Looareesuwan, S; Rumpold, H; Schönthal, E; Vannaphan, S; Wagner, O; Wenisch, C; Wenisch, H; Wilairatana, P	1
Brittenham, GM; Gordeuk, VR; Looareesuwan, S; Meshnick, SR; Taylor, TE; Vannaphan, S; Wilairatana, P	1
Andrial, M; Chalermrut, K; Looareesuwan, S; Molunto, W; Olliaro, P; Wilairatana, P	1
Newton, CR; Warrell, DA	1
Linnau, KF; Looaresuwan, S; Rumpold, H; Wenisch, C	1
Aursudkij, B; Gordeux, VR; Looareesuwan, S; Vannaphan, S; Walsh, DS; Wilairatana, P	1
Brittenham, G; Kreil, A; Looareesuwan, S; Peck-Radosavljevic, M; Wenisch, C	1
Chanthavanich, P; Chokejindachai, W; Kabkaew, K; Pengsaa, K; Saelim, R; Sirivichayakul, C	1
Agbenyega, T; Agranoff, D; Appiah, JA; Bedu-Addo, G; Krishna, S; Mansor, SM; Navaratnam, V; Owusu-Ofori, AK; Planche, T; Ramanathan, S; Woodrow, C	1
Adabayeri, V; Akanmori, BD; Asare-Odei, G; Goka, BQ; Kurtzhals, J; Neequaye, J; Ofori-Adjei, D; Ofori-Adjei, E; Quarshie, B	1
Lalloo, D; Trevett, A	1
Than, M; Thwe, Y; Win, K	1

Reviews

7 review(s) available for artesunic acid and Cerebral Malaria

Article	Year
Comparative efficacy and safety of the artemisinin derivatives compared to quinine for treating severe malaria in children and adults: A systematic update of literature and network meta-analysis. PloS one, 2022, Volume: 17, Issue:7 Topics: Adult; Antimalarials; Artemether; Artemisinins; Artesunate; Child; Humans; Malaria, Cerebral; Malaria, Falciparum; Network Meta-Analysis; Quinine	2022
Artemether for severe malaria. The Cochrane database of systematic reviews, 2019, 06-18, Volume: 6 Topics: Adolescent; Adult; Africa; Age Factors; Antimalarials; Artemether; Artesunate; Asia; Child; Child, Preschool; Coma; Fever; Humans; Infant; Injections, Intramuscular; Malaria, Cerebral; Malaria, Falciparum; Oceania; Quinine; Randomized Controlled Trials as Topic; Treatment Outcome	2019
Artemether for severe malaria. The Cochrane database of systematic reviews, 2014, Sep-11, Issue:9 Topics: Adolescent; Adult; Africa; Antimalarials; Artemether; Artemisinins; Artesunate; Asia; Child; Child, Preschool; Humans; Infant; Injections, Intramuscular; Malaria, Cerebral; Malaria, Falciparum; Oceania; Quinine; Randomized Controlled Trials as Topic	2014
[Cerebral malaria]. Brain and nerve = Shinkei kenkyu no shinpo, 2009, Volume: 61, Issue:2 Topics: Animals; Antimalarials; Artemisinins; Artesunate; Hemodiafiltration; Humans; Infusions, Intravenous; Magnetic Resonance Imaging; Malaria, Cerebral; Plasmodium falciparum; Plasmodium vivax; Quinine; Renal Dialysis; Tomography, X-Ray Computed	2009
Adjunctive management of malaria. Current opinion in infectious diseases, 2012, Volume: 25, Issue:5 Topics: Antimalarials; Artemisinins; Artesunate; Blood Transfusion; Fluid Therapy; Humans; Malaria; Malaria, Cerebral; Nitric Oxide	2012
Neurological manifestations of falciparum malaria. Annals of neurology, 1998, Volume: 43, Issue:6 Topics: Adult; Antimalarials; Artemether; Artemisinins; Artesunate; Child; Humans; Malaria, Cerebral; Quinidine; Quinine; Sesquiterpenes	1998
A new look at an old drug: artemesinin and qinghaosu. Papua and New Guinea medical journal, 1992, Volume: 35, Issue:4 Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Humans; Malaria, Cerebral; Malaria, Falciparum; Sesquiterpenes	1992

Trials

12 trial(s) available for artesunic acid and Cerebral Malaria

Article	Year
Efficacy and safety of dual intravenous artesunate plus quinine compared to intravenous artesunate for cerebral malaria in a triple blinded parallel multisite randomized controlled trial in Nigerian children: DUAL PAQ TRIAL Protocol. Trials, 2021, Oct-20, Volume: 22, Issue:1 Topics: Antimalarials; Artemisinins; Artesunate; Child; Humans; Malaria, Cerebral; Neoplasm Recurrence, Local; Nigeria; Quinine; Randomized Controlled Trials as Topic	2021
Efficacy of intranasal administration of artesunate in experimental cerebral malaria. Malaria journal, 2014, Dec-16, Volume: 13 Topics: Administration, Intranasal; Animals; Antimalarials; Artemisinins; Artesunate; Blood Chemical Analysis; Brain Chemistry; Disease Models, Animal; Female; Malaria, Cerebral; Mice, Inbred CBA; Parasitemia; Placebos; Random Allocation; Single-Blind Method; Survival Analysis; Treatment Outcome	2014
Dysregulation of angiopoietin-1 plays a mechanistic role in the pathogenesis of cerebral malaria. Science translational medicine, 2016, 09-28, Volume: 8, Issue:358 Topics: Adenoviridae; Angiopoietin-1; Animals; Antimalarials; Artemisinins; Artesunate; Blood-Brain Barrier; Child, Preschool; Disease Models, Animal; Disease Susceptibility; Endothelial Cells; Female; Gene Deletion; Humans; Infant; Kaplan-Meier Estimate; Kinetics; Malaria, Cerebral; Malaria, Falciparum; Male; Mice, Inbred C57BL; Phenotype; Plasmodium falciparum; Receptor, TIE-2; Recombinant Proteins; Survival Analysis; Treatment Outcome; Uganda	2016
Oral activated charcoal prevents experimental cerebral malaria in mice and in a randomized controlled clinical trial in man did not interfere with the pharmacokinetics of parenteral artesunate. PloS one, 2010, Apr-15, Volume: 5, Issue:4 Topics: Administration, Oral; Adult; Animals; Antimalarials; Artemisinins; Artesunate; Charcoal; Drug Evaluation, Preclinical; Drug Interactions; Female; Humans; Infusions, Parenteral; Malaria, Cerebral; Male; Mice; Mice, Inbred C57BL; Middle Aged; Plasmodium berghei; Survival Rate	2010
Penetration of dihydroartemisinin into cerebrospinal fluid after administration of intravenous artesunate in severe falciparum malaria. Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:1 Topics: Adolescent; Adult; Artemisinins; Artesunate; Chromatography, High Pressure Liquid; Female; Half-Life; Humans; Injections, Intravenous; Malaria, Cerebral; Malaria, Falciparum; Male; Middle Aged; Sesquiterpenes	2003
Curdlan sulphate in human severe/cerebral Plasmodium falciparum malaria. Transactions of the Royal Society of Tropical Medicine and Hygiene, 2005, Volume: 99, Issue:5 Topics: Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; beta-Glucans; Child; Double-Blind Method; Drug Therapy, Combination; Female; Fever; Humans; Malaria, Cerebral; Malaria, Falciparum; Male; Middle Aged; Parasitemia; Sesquiterpenes; Treatment Outcome	2005
Life-saving rectal artesunate for complicated malaria in children. The Southeast Asian journal of tropical medicine and public health, 2005, Volume: 36, Issue:3 Topics: Administration, Rectal; Animals; Antimalarials; Artemisinins; Artesunate; Child; Child Welfare; Child, Preschool; Drug Resistance, Multiple; Drug Therapy, Combination; Humans; Malaria, Cerebral; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Sesquiterpenes; Suppositories; Thailand; Treatment Outcome	2005
Co-administration of desferrioxamine B with artesunate in malaria: an assessment of safety and tolerance. Annals of tropical medicine and parasitology, 1996, Volume: 90, Issue:5 Topics: Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Deferoxamine; Drug Therapy, Combination; Female; Humans; Malaria, Cerebral; Malaria, Falciparum; Male; Prospective Studies; Sesquiterpenes; Single-Blind Method	1996
A comparative clinical trial of sequential treatments of severe malaria with artesunate suppository followed by mefloquine in Thailand. The American journal of tropical medicine and hygiene, 1997, Volume: 57, Issue:3 Topics: Administration, Oral; Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Drug Therapy, Combination; Female; Humans; Malaria; Malaria, Cerebral; Male; Mefloquine; Middle Aged; Sesquiterpenes; Single-Blind Method; Suppositories; Thailand	1997
Bioavailability and preliminary clinical efficacy of intrarectal artesunate in Ghanaian children with moderate malaria. Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:2 Topics: Administration, Rectal; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Female; Follow-Up Studies; Ghana; Humans; Infant; Injections, Intravenous; Malaria; Malaria, Cerebral; Male; Sesquiterpenes	2001
Comparison of chloroquine with artesunate in the treatment of cerebral malaria in Ghanaian children. Journal of tropical pediatrics, 2001, Volume: 47, Issue:3 Topics: Animals; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Female; Ghana; Humans; Malaria, Cerebral; Male; Plasmodium falciparum; Sesquiterpenes	2001
Comparison of combinations of parenteral artemisinin derivatives plus oral mefloquine with intravenous quinine plus oral tetracycline for treating cerebral malaria. Bulletin of the World Health Organization, 1992, Volume: 70, Issue:6 Topics: Adolescent; Adult; Antimalarials; Artemether; Artemisinins; Artesunate; Humans; Malaria, Cerebral; Mefloquine; Middle Aged; Prospective Studies; Quinine; Sesquiterpenes; Tetracycline	1992

Other Studies

46 other study(ies) available for artesunic acid and Cerebral Malaria

Article	Year
Plasmodium falciparum clearance time in Malawian children with cerebral malaria: a retrospective cohort study. Malaria journal, 2021, Oct-18, Volume: 20, Issue:1 Topics: Adolescent; Antimalarials; Artesunate; Child; Child, Preschool; Cohort Studies; Female; Humans; Infant; Malaria, Cerebral; Malaria, Falciparum; Malawi; Male; Plasmodium falciparum; Quinine; Retrospective Studies; Time Factors	2021
Congenital cerebral malaria: a masquerader in a neonate. Malaria journal, 2022, Feb-05, Volume: 21, Issue:1 Topics: Anemia; Artesunate; Female; Fetal Diseases; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Malaria, Cerebral; Male; Pregnancy	2022
RNA-seq-based transcriptome analysis of the anti-inflammatory effect of artesunate in the early treatment of the mouse cerebral malaria model. Molecular omics, 2022, 09-26, Volume: 18, Issue:8 Topics: Animals; Anti-Inflammatory Agents; Antimalarials; Artemisinins; Artesunate; Disease Models, Animal; Gene Expression Profiling; Intercellular Adhesion Molecule-1; Interleukin-10; Interleukin-6; Lead; Malaria, Cerebral; Mice; Mice, Inbred C57BL; RNA-Seq; Toll-Like Receptors; Tumor Necrosis Factor-alpha	2022
Pre-referral intranasal artesunate powder for cerebral malaria: a proof-of-concept study. Malaria journal, 2022, Oct-11, Volume: 21, Issue:1 Topics: Administration, Intranasal; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Humans; Malaria, Cerebral; Powders; Referral and Consultation; Suppositories	2022
Efficacy of artesunate combined with Atractylodes lancea or Prabchompoothaweep remedy extracts as adjunctive therapy for the treatment of cerebral malaria. BMC complementary medicine and therapies, 2023, Sep-20, Volume: 23, Issue:1 Topics: Animals; Antimalarials; Artesunate; Atractylodes; Malaria, Cerebral; Male; Mice; Mice, Inbred C57BL	2023
Synergistic Effect of Combined Artesunate and Tetramethylpyrazine in Experimental Cerebral Malaria. ACS infectious diseases, 2020, 09-11, Volume: 6, Issue:9 Topics: Animals; Antimalarials; Artesunate; Malaria, Cerebral; Mice; Mice, Inbred C57BL; Pyrazines; Vascular Endothelial Growth Factor A	2020
Intranasal artesunate-loaded nanostructured lipid carriers: A convenient alternative to parenteral formulations for the treatment of severe and cerebral malaria. Journal of controlled release : official journal of the Controlled Release Society, 2021, 06-10, Volume: 334 Topics: Administration, Intranasal; Animals; Artesunate; Child, Preschool; Drug Carriers; Humans; Lipids; Malaria, Cerebral; Mice; Nanostructures; Particle Size; Swine	2021
Transdermal delivery of artemisinins for treatment of pre-clinical cerebral malaria. International journal for parasitology. Drugs and drug resistance, 2021, Volume: 16 Topics: Animals; Antimalarials; Artemisinins; Artesunate; Humans; Malaria, Cerebral; Mice; Plasmodium berghei	2021
Artesunate and Tetramethylpyrazine Exert Effects on Experimental Cerebral Malaria in a Mechanism of Protein ACS infectious diseases, 2021, 10-08, Volume: 7, Issue:10 Topics: Artesunate; Humans; Malaria, Cerebral; Nitric Oxide; Protein S; Pyrazines	2021
Artesunate and erythropoietin synergistically improve the outcome of experimental cerebral malaria. International immunopharmacology, 2017, Volume: 48 Topics: Animals; Antimalarials; Artemisinins; Artesunate; Brain; Cytokines; Dendritic Cells; Disease Models, Animal; Drug Synergism; Erythropoietin; Female; Intercellular Adhesion Molecule-1; Malaria, Cerebral; Mice, Inbred C57BL; Plasmodium berghei; Spleen; T-Lymphocytes; Vascular Cell Adhesion Molecule-1	2017
Efficacy and safety evaluation of a novel trioxaquine in the management of cerebral malaria in a mouse model. Malaria journal, 2017, 07-03, Volume: 16, Issue:1 Topics: Animals; Antimalarials; Artemisinins; Artesunate; Blood-Brain Barrier; Disease Models, Animal; Drug Evaluation; Heterocyclic Compounds; Malaria, Cerebral; Male; Mice; Mice, Inbred C57BL; Parasitemia; Plasmodium berghei; Quinine; Quinolines; Random Allocation; Safety	2017
Infection and immunity, 2017, Volume: 85, Issue:9 Topics: Alcohol Dehydrogenase; Animals; Antimalarials; Artemisinins; Artesunate; Disease Models, Animal; Female; Malaria, Cerebral; Male; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Plasmodium berghei; Survival Analysis; T-Lymphocytes; Treatment Outcome	2017
Malaria: diagnosis, treatment and management of a critically ill patient. British journal of nursing (Mark Allen Publishing), 2017, Jul-13, Volume: 26, Issue:13 Topics: Adolescent; Antimalarials; Artemisinins; Artesunate; Critical Care Nursing; Critical Illness; Fatal Outcome; Female; Humans; Malaria, Cerebral; Malaria, Falciparum	2017
Severe malaria presenting to the ED: A collaborative approach utilizing exchange transfusion and artesunate. The American journal of emergency medicine, 2018, Volume: 36, Issue:6 Topics: Adult; Antimalarials; Artesunate; Critical Care; Emergency Medical Services; Exchange Transfusion, Whole Blood; Humans; Infectious Disease Medicine; Intersectoral Collaboration; Malaria, Cerebral; Male; Parasitemia; Severity of Illness Index; Treatment Outcome	2018
[Protective effects of artesunate combination on experimental cerebral malaria and nerve injury]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2018, Volume: 43, Issue:15 Topics: Animals; Antimalarials; Artesunate; Disease Models, Animal; Malaria, Cerebral; Mice; Mice, Inbred C57BL; Plasmodium berghei	2018
Reversal of cerebrovascular constriction in experimental cerebral malaria by L-arginine. Scientific reports, 2018, 10-29, Volume: 8, Issue:1 Topics: Animals; Antimalarials; Arginine; Artesunate; Cerebral Arteries; Dose-Response Relationship, Drug; Female; Malaria, Cerebral; Mice; Mice, Inbred C57BL; Nitric Oxide Donors; Nitric Oxide Synthase; Plasmodium berghei; Survival Rate; Vasoconstriction	2018
Investigation of hydrogen sulfide gas as a treatment against P. falciparum, murine cerebral malaria, and the importance of thiolation state in the development of cerebral malaria. PloS one, 2013, Volume: 8, Issue:3 Topics: Animals; Antimalarials; Artemisinins; Artesunate; Blood Platelets; Dose-Response Relationship, Drug; Erythrocytes; Humans; Hydrogen Sulfide; Malaria, Cerebral; Mice; Mice, Inbred C57BL; Morpholines; Organothiophosphorus Compounds; Plasmodium berghei; Plasmodium falciparum; Species Specificity; Sulfhydryl Compounds; Sulfides	2013
Slow and continuous delivery of a low dose of nimodipine improves survival and electrocardiogram parameters in rescue therapy of mice with experimental cerebral malaria. Malaria journal, 2013, Apr-24, Volume: 12 Topics: Administration, Intravenous; Animals; Antihypertensive Agents; Antimalarials; Artemisinins; Artesunate; Disease Models, Animal; Electrocardiography; Female; Malaria, Cerebral; Mice; Mice, Inbred C57BL; Nimodipine; Plasmodium berghei; Salvage Therapy; Survival Analysis; Treatment Outcome	2013
Potential efficacy of citicoline as adjunct therapy in treatment of cerebral malaria. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:1 Topics: Animals; Antimalarials; Artemisinins; Artesunate; Cytidine Diphosphate Choline; Female; Humans; Malaria, Cerebral; Mice	2014
Further evidence for an anti-inflammatory role of artesunate in experimental cerebral malaria. Malaria journal, 2013, Nov-02, Volume: 12 Topics: Animals; Anti-Inflammatory Agents; Antimalarials; Artemisinins; Artesunate; Cytokines; Cytological Techniques; Disease Models, Animal; Female; Frontal Lobe; Gene Expression Profiling; Hippocampus; Malaria, Cerebral; Mice; Mice, Inbred C57BL; Plasmodium berghei; Real-Time Polymerase Chain Reaction; RNA, Messenger; Survival Analysis	2013
Factors associated with cerebral malaria. The Southeast Asian journal of tropical medicine and public health, 2013, Volume: 44, Issue:6 Topics: Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Body Mass Index; Case-Control Studies; Female; Humans; Malaria, Cerebral; Male; Mefloquine; Plasmodium falciparum; Retrospective Studies; Thailand	2013
Cerebral malaria due to Plasmodium vivax in a young infant. Indian journal of pediatrics, 2014, Volume: 81, Issue:12 Topics: Anticonvulsants; Antimalarials; Artemisinins; Artesunate; Diagnosis, Differential; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Cerebral; Malaria, Vivax; Phenytoin	2014
Inhibition of metalloproteinase-9 secretion and gene expression by artemisinin derivatives. Acta tropica, 2014, Volume: 140 Topics: Artemisinins; Artesunate; Cytokines; Gene Expression Regulation; Humans; Inflammation Mediators; Malaria, Cerebral; Malaria, Falciparum; Matrix Metalloproteinase 9; Monocytes; Plasmodium falciparum; Polymerase Chain Reaction; RNA, Messenger	2014
Cannabidiol increases survival and promotes rescue of cognitive function in a murine model of cerebral malaria. Neuroscience, 2015, Mar-19, Volume: 289 Topics: Animals; Antimalarials; Anxiety; Artemisinins; Artesunate; Brain-Derived Neurotrophic Factor; Cannabidiol; Cognition; Disease Models, Animal; Drug Therapy, Combination; Female; Hippocampus; Malaria, Cerebral; Memory Disorders; Mice, Inbred C57BL; Nerve Growth Factor; Neuroprotective Agents; Plasmodium berghei; Prefrontal Cortex; Survival Analysis; Treatment Outcome	2015
Altered Mental Status and Fever. The Journal of emergency medicine, 2015, Volume: 49, Issue:2 Topics: Anti-Bacterial Agents; Antimalarials; Artemisinins; Artesunate; Ceftriaxone; Child; Confusion; Drug Therapy, Combination; Emergency Service, Hospital; Exchange Transfusion, Whole Blood; Female; Fever; Ghana; Humans; Malaria, Cerebral; Massachusetts; Parasitemia; Travel; Vancomycin	2015
NO-Donor Dihydroartemisinin Derivatives as Multitarget Agents for the Treatment of Cerebral Malaria. Journal of medicinal chemistry, 2015, Oct-08, Volume: 58, Issue:19 Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Chemistry Techniques, Synthetic; Malaria, Cerebral; Mice; Molecular Targeted Therapy; Muscle Relaxation; Nitric Oxide Donors; Plasmodium berghei; Rats; Vasodilator Agents	2015
Cerebral malaria in a man with Plasmodium vivax mono-infection: a case report. Tropical doctor, 2016, Volume: 46, Issue:4 Topics: Administration, Intravenous; Administration, Oral; Antimalarials; Artemisinins; Artesunate; Doxycycline; Female; Humans; Malaria, Cerebral; Malaria, Vivax; Male; Plasmodium vivax; Polymerase Chain Reaction; Seizures; Treatment Outcome; Young Adult	2016
Plasmodium vivax Malaria Presenting with Multifocal Hemorrhagic Brain Infarcts in a School-going Child. Journal of tropical pediatrics, 2016, Volume: 62, Issue:4 Topics: Acute Febrile Encephalopathy; Anti-Bacterial Agents; Antimalarials; Artemisinins; Artesunate; Brain; Child; Clindamycin; Electroencephalography; Humans; Intensive Care Units, Pediatric; Intracranial Pressure; Malaria, Cerebral; Malaria, Vivax; Male; Plasmodium vivax; Treatment Outcome	2016
Severe Plasmodium vivax cerebral malaria complicated by hemophagocytic lymphohistiocytosis treated with artesunate and doxycycline. Hematology/oncology and stem cell therapy, 2018, Volume: 11, Issue:1 Topics: Adult; Artemisinins; Artesunate; Doxycycline; Humans; Lymphohistiocytosis, Hemophagocytic; Malaria, Cerebral; Malaria, Vivax; Male; Plasmodium vivax	2018
Statins alone are ineffective in cerebral malaria but potentiate artesunate. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:11 Topics: Animals; Antimalarials; Artemisinins; Artesunate; Atorvastatin; Disease Models, Animal; Drug Synergism; Fatty Acids, Monounsaturated; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Malaria, Cerebral; Malaria, Falciparum; Mice; Neuroprotective Agents; Pravastatin; Pyrroles; Simvastatin	2008
Childhood cerebral vivax malaria with pancytopenia. Journal of pediatric hematology/oncology, 2009, Volume: 31, Issue:2 Topics: Animals; Artemisinins; Artesunate; Child; Female; Humans; Malaria, Cerebral; Malaria, Vivax; Pancytopenia; Plasmodium vivax; Trophozoites	2009
Artemether and artesunate show the highest efficacies in rescuing mice with late-stage cerebral malaria and rapidly decrease leukocyte accumulation in the brain. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:4 Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Brain; Leukocytes; Malaria, Cerebral; Mefloquine; Mice; Parasitemia; Plasmodium berghei; Quinine	2011
S1P is associated with protection in human and experimental cerebral malaria. Molecular medicine (Cambridge, Mass.), 2011, Volume: 17, Issue:7-8 Topics: Aldehyde-Lyases; Animals; Antimalarials; Artemisinins; Artesunate; Brain; Cell Adhesion Molecules; Child; Child, Preschool; Female; Fingolimod Hydrochloride; Humans; Imidazoles; Immunosuppressive Agents; Infant; Interferon-gamma; Lysophospholipids; Malaria, Cerebral; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Oximes; Plasmodium berghei; Propylene Glycols; Sphingosine; Survival Analysis; T-Lymphocytes; Treatment Outcome	2011
Inhaled nitric oxide reduces endothelial activation and parasite accumulation in the brain, and enhances survival in experimental cerebral malaria. PloS one, 2011, Volume: 6, Issue:11 Topics: Administration, Inhalation; Animals; Artemisinins; Artesunate; Blood Vessels; Blood-Brain Barrier; Brain; Endothelial Cells; Gene Expression Regulation; Inflammation; Intercellular Adhesion Molecule-1; Malaria, Cerebral; Male; Mice; Nitric Oxide; Plasmodium berghei; Survival Analysis; Time Factors	2011
Oral artesunate prevents Plasmodium berghei Anka infection in mice. Parasitology international, 2003, Volume: 52, Issue:1 Topics: Administration, Oral; Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Therapy, Combination; Malaria, Cerebral; Mice; Mice, Inbred C57BL; Plasmodium berghei; Sesquiterpenes	2003
Successful treatment of imported cerebral malaria with artesunate-mefloquine combination therapy. Journal of the Formosan Medical Association = Taiwan yi zhi, 2006, Volume: 105, Issue:1 Topics: Adult; Antimalarials; Artemisinins; Artesunate; Drug Therapy, Combination; Female; Humans; Malaria, Cerebral; Mefloquine; Reticulocytes; Sesquiterpenes; Travel; Treatment Outcome	2006
Cerebral malaria in spite of peripheral parasite clearance in a patient treated with atovaquone/proguanil. Parasitology research, 2007, Volume: 100, Issue:4 Topics: Adult; Animals; Antimalarials; Artemisinins; Artesunate; Atovaquone; Female; Humans; Malaria, Cerebral; Plasmodium falciparum; Proguanil; Quinine; Sesquiterpenes	2007
Plasmodium vivax cerebral malaria. Indian pediatrics, 2007, Volume: 44, Issue:6 Topics: Animals; Artemisinins; Artesunate; Central Nervous System Protozoal Infections; Child; Humans; Malaria; Malaria, Cerebral; Male; Plasmodium vivax; Sesquiterpenes	2007
Artesunate-erythropoietin combination for murine cerebral malaria treatment. Acta tropica, 2008, Volume: 106, Issue:2 Topics: Animals; Artemisinins; Artesunate; Drug Therapy, Combination; Erythropoietin; Female; Malaria, Cerebral; Mice; Mice, Inbred CBA; Plasmodium berghei; Survival Analysis; Time Factors; Treatment Outcome	2008
A nonhuman primate model for human cerebral malaria: effects of artesunate (qinghaosu derivative) on rhesus monkeys experimentally infected with Plasmodium coatneyi. The American journal of tropical medicine and hygiene, 1993, Volume: 49, Issue:6 Topics: Animals; Artemisinins; Artesunate; Brain; Cell Adhesion; Cell Adhesion Molecules; Complement C3; Disease Models, Animal; E-Selectin; Erythrocytes; Fluorescent Antibody Technique; Immunoglobulin G; Intercellular Adhesion Molecule-1; Macaca mulatta; Malaria, Cerebral; Microcirculation; Microscopy, Electron; Plasmodium; Sesquiterpenes	1993
Clinical trials of artemisinin and its derivatives in the treatment of malaria in China. Transactions of the Royal Society of Tropical Medicine and Hygiene, 1994, Volume: 88 Suppl 1 Topics: Antimalarials; Antiprotozoal Agents; Artemisinins; Artesunate; China; Clinical Trials as Topic; Humans; Injections, Intramuscular; Injections, Intravenous; Malaria, Cerebral; Malaria, Falciparum; Sesquiterpenes; Suppositories; Tablets	1994
Big endothelin in patients with complicated Plasmodium falciparum malaria. The Journal of infectious diseases, 1996, Volume: 173, Issue:5 Topics: Antimalarials; Artemisinins; Artesunate; Endothelin-1; Endothelins; Enzyme-Linked Immunosorbent Assay; Humans; Interleukin-6; Malaria, Cerebral; Malaria, Falciparum; Matched-Pair Analysis; Platelet Count; Protein Precursors; Renal Insufficiency; Sesquiterpenes; Tumor Necrosis Factor-alpha	1996
Plasma levels of the interleukin-6 cytokine family in persons with severe Plasmodium falciparum malaria. The Journal of infectious diseases, 1999, Volume: 179, Issue:3 Topics: Acute Kidney Injury; Adolescent; Adult; Animals; Antimalarials; Artemisinins; Artesunate; Biomarkers; Ciliary Neurotrophic Factor; Female; Humans; Interleukin-6; Malaria; Malaria, Cerebral; Malaria, Falciparum; Male; Middle Aged; Nerve Growth Factors; Nerve Tissue Proteins; Plasmodium falciparum; Receptors, Interleukin-6; Reference Values; Sesquiterpenes	1999
Pulmonary edema in cerebral malaria patients in Thailand. The Southeast Asian journal of tropical medicine and public health, 1998, Volume: 29, Issue:3 Topics: Adolescent; Adult; Aged; Antimalarials; APACHE; Artemisinins; Artesunate; Drug Administration Schedule; Female; Humans; Intensive Care Units; Malaria, Cerebral; Male; Mefloquine; Middle Aged; Prognosis; Prospective Studies; Pulmonary Edema; Respiratory Distress Syndrome; Sesquiterpenes; Thailand	1998
Thrombopoietin in Plasmodium falciparum malaria. British journal of haematology, 2000, Volume: 109, Issue:3 Topics: Acute Kidney Injury; Antimalarials; Artemisinins; Artesunate; Humans; Malaria, Cerebral; Malaria, Falciparum; Platelet Count; Sesquiterpenes; Statistics, Nonparametric; Thrombopoietin	2000
Pleural effusion in childhood falciparum malaria. The Southeast Asian journal of tropical medicine and public health, 2000, Volume: 31, Issue:1 Topics: Albumins; Anticonvulsants; Antimalarials; Artemisinins; Artesunate; Child; Combined Modality Therapy; Drug Therapy, Combination; Furosemide; Humans; Intubation, Intratracheal; Malaria, Cerebral; Male; Pleural Effusion; Sesquiterpenes	2000