Page last updated: 2024-08-26

artesunic acid and Blood Poisoning

artesunic acid has been researched along with Blood Poisoning in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (50.00)24.3611
2020's5 (50.00)2.80

Authors

AuthorsStudies
Bai, YM; Chen, JY; Feng, YL; Gao, P; He, XL; Jiang, Y; Li, ZJ; Liao, FL; Liu, Q; Luo, P; Song, P; Wang, C; Wang, JG; Wong, YK; Xie, LL; Zhang, Q1
Chen, X; Hua, L; Huang, Y; Liu, D; Liu, X; Long, S; Ouyang, F; Yuan, Y; Zheng, J; Zhou, H; Zhou, J1
Li, P; Li, X; Liu, S; Liu, X; Shang, S; Wang, Y; Wu, J; Zheng, C; Zheng, J; Zhou, H1
Chen, Q; Jiang, N; Ju, X; Li, D; Wang, J; Wang, Z; Zhang, E1
Bang, S; Bortsov, AV; Chandra, S; Derbyshire, ER; Donnelly, CR; Ji, RR; Luo, X; Tao, X; Toro-Moreno, M; Wang, Z1
Buffet, P; Chotivanich, K; Day, NPJ; Dondorp, AM; Fanello, C; Jauréguiberry, S; Lee, SJ; Onyamboko, M; Rockett, K; Setaphan, S; Stepniewska, K; White, NJ; Woodrow, C1
Jiang, W; Li, B; Li, X; Pan, X; Peng, W; Ren, C; Yu, M; Zheng, J; Zhou, H1
Cao, TH; Fei, DS; Jiang, L; Jin, SG; Kang, K; Lian, ZY; Pan, SH; Zhao, MR; Zhao, MY1
Cao, H; Ding, G; Jiang, W; Li, B; Li, J; Pan, X; Zheng, J; Zhou, H1
Cao, H; Cen, Y; Jiang, W; Li, B; Li, J; Liu, X; Pan, X; Zheng, J; Zheng, X; Zhou, H1

Trials

1 trial(s) available for artesunic acid and Blood Poisoning

ArticleYear
Post-treatment haemolysis in African children with hyperparasitaemic falciparum malaria; a randomized comparison of artesunate and quinine.
    BMC infectious diseases, 2017, 08-17, Volume: 17, Issue:1

    Topics: Administration, Intravenous; Adolescent; Anemia, Hemolytic; Antimalarials; Artemisinins; Artesunate; Blood Transfusion; Child; Child, Preschool; Democratic Republic of the Congo; Erythrocytes; Female; Hemolysis; Hospitalization; Humans; Infant; Malaria, Falciparum; Male; Quinine; Sepsis

2017

Other Studies

9 other study(ies) available for artesunic acid and Blood Poisoning

ArticleYear
Single-cell RNA sequencing deciphers the mechanism of sepsis-induced liver injury and the therapeutic effects of artesunate.
    Acta pharmacologica Sinica, 2023, Volume: 44, Issue:9

    Topics: Animals; Artesunate; Chemical and Drug Induced Liver Injury, Chronic; Endothelial Cells; Mice; Sepsis; Sequence Analysis, RNA

2023
The effect of artesunate to reverse CLP-induced sepsis immunosuppression mice with secondary infection is tightly related to reducing the apoptosis of T cells via decreasing the inhibiting receptors and activating MAPK/ERK pathway.
    International immunopharmacology, 2023, Volume: 124, Issue:Pt A

    Topics: Animals; Apoptosis; Artesunate; CD8-Positive T-Lymphocytes; Coinfection; Cytokines; Disease Models, Animal; Immunosuppression Therapy; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Pseudomonas Infections; Punctures; Sepsis

2023
Artesunate interacts with the vitamin D receptor to reverse sepsis-induced immunosuppression in a mouse model via enhancing autophagy.
    British journal of pharmacology, 2020, Volume: 177, Issue:18

    Topics: Animals; Artesunate; Autophagy; Female; Immunosuppression Therapy; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Receptors, Calcitriol; Sepsis

2020
Artesunate ameliorates sepsis-induced acute lung injury by activating the mTOR/AKT/PI3K axis.
    Gene, 2020, Oct-30, Volume: 759

    Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Apoptosis; Artesunate; Interleukin-6; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Sepsis; Signal Transduction; TOR Serine-Threonine Kinases; Tumor Necrosis Factor-alpha

2020
Activation of GPR37 in macrophages confers protection against infection-induced sepsis and pain-like behaviour in mice.
    Nature communications, 2021, 03-17, Volume: 12, Issue:1

    Topics: Adoptive Transfer; Animals; Artesunate; Disease Models, Animal; Docosahexaenoic Acids; Lipopolysaccharides; Listeria monocytogenes; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Docking Simulation; Pain; Phagocytosis; Plasmodium berghei; Receptors, G-Protein-Coupled; Sepsis

2021
Artesunate reduces serum lipopolysaccharide in cecal ligation/puncture mice via enhanced LPS internalization by macrophages through increased mRNA expression of scavenger receptors.
    International journal of molecular sciences, 2014, Jan-16, Volume: 15, Issue:1

    Topics: Animals; Artemisinins; Artesunate; Cecum; Cell Culture Techniques; Cells, Cultured; Lipopolysaccharides; Macrophages; Mice; Receptors, Immunologic; RNA, Messenger; Scavenger Receptors, Class A; Sepsis

2014
Artesunate Protects Against Sepsis-Induced Lung Injury Via Heme Oxygenase-1 Modulation.
    Inflammation, 2016, Volume: 39, Issue:2

    Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Artemisinins; Artesunate; Bronchoalveolar Lavage Fluid; Cecum; Cyclooxygenase 2; Enzyme Activation; Heme Oxygenase-1; Interleukin-6; Lung; Male; Mice; Neutrophil Infiltration; NF-E2-Related Factor 2; NF-kappa B; Nitric Oxide Synthase Type II; Protoporphyrins; Sepsis; Signal Transduction; Tumor Necrosis Factor-alpha

2016
Artesunate protects sepsis model mice challenged with Staphylococcus aureus by decreasing TNF-alpha release via inhibition TLR2 and Nod2 mRNA expressions and transcription factor NF-kappaB activation.
    International immunopharmacology, 2010, Volume: 10, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Artemisinins; Artesunate; Cells, Cultured; Cytokines; Dose-Response Relationship, Drug; Female; Indicators and Reagents; Inflammation; Macrophages; Male; Mice; NF-kappa B; Nod2 Signaling Adaptor Protein; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sepsis; Staphylococcal Infections; Toll-Like Receptor 2; Tumor Necrosis Factor-alpha

2010
Artesunate in combination with oxacillin protect sepsis model mice challenged with lethal live methicillin-resistant Staphylococcus aureus (MRSA) via its inhibition on proinflammatory cytokines release and enhancement on antibacterial activity of oxacilli
    International immunopharmacology, 2011, Volume: 11, Issue:8

    Topics: Adenosine; Ampicillin; Animals; Anti-Bacterial Agents; Antigens, CD; Artemisinins; Artesunate; Bacterial Load; beta-Lactams; Cytokines; Down-Regulation; Drug Synergism; Drug Therapy, Combination; Female; Interleukin-6; Macrophages, Peritoneal; Male; Methicillin-Resistant Staphylococcus aureus; Mice; Microbial Sensitivity Tests; Nod2 Signaling Adaptor Protein; Oxacillin; Penicillin-Binding Proteins; Sepsis; Staphylococcal Infections; Toll-Like Receptor 2; Tumor Necrosis Factor-alpha

2011