artenimol has been researched along with Plasmodium falciparum Malaria in 409 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 22 (5.38) | 18.2507 |
2000's | 86 (21.03) | 29.6817 |
2010's | 214 (52.32) | 24.3611 |
2020's | 87 (21.27) | 2.80 |
Authors | Studies |
---|---|
Ge, J; Huang, Z; Jiang, L; Li, J; Li, X; Rao, Y; Wu, Y; Yang, M; Yang, Y; Yu, J; Yu, Y | 1 |
Boonhok, R; Chakrabarti, D; Huang, G; Melendez, J; Miao, J; Min, H; Solano, CM; Yu-Alfonzo, S; Yuan, Y | 1 |
Ding, Y; Huang, Z; Jiang, L; Li, J; Li, R; Li, X; Ling, D; Liu, T; Mao, F; Tang, T; Wang, M; Wei, H; Xu, W; Zhu, J | 1 |
Avery, VM; Challis, MP; Creek, DJ; De Paoli, A; Devine, SM; Kigotho, JK; MacRaild, CA; Norton, RS; Scammells, PJ; Siddiqui, G | 1 |
Arimondo, PB; Bon, C; Cadet-Daniel, V; Claes, A; Dobrescu, I; Erdmann, D; Halby, L; Hammam, E; Mairet-Khedim, M; Mecheri, S; Nardella, F; Peronet, R; Roesch, C; Scherf, A; Tafit, A; Viluma, J; Witkowski, B | 1 |
Avery, MA; Bandyopadhyaya, AK; Desai, PV; Furtado, MM; Muraleedharan, KM; Tekwani, BL | 1 |
Brun, R; Charman, SA; Charman, WN; Chiu, FC; Chollet, J; Dong, Y; Dorn, A; Karle, JM; Matile, H; Santo Tomas, J; Scheurer, C; Scorneaux, B; Snyder, C; Tang, Y; Urwyler, H; Vennerstrom, JL; Wang, X; Wittlin, S | 1 |
Fukuda, M; Jongsakul, K; Knirsch, C; Krudsood, S; Leowattana, W; Looareesuwan, S; Miller, RS; Noedl, H; Ohrt, C; Sriwichai, S; Tangpukdee, N; Thanachartwet, W; Yingyuen, K | 1 |
Bui, D; Chavchich, M; Dinh, DN; Edstein, MD; Le, TT; Nguyen, DV; Nguyen, ND; Nguyen, QP; Nguyen, TD; Nguyen, TX | 1 |
Abdirahman, A; Borrmann, S; Bull, P; Diriye, A; Kiara, SM; Marsh, K; Mwai, L; Nzila, A; Pole, L; Rippert, A | 1 |
Bunchalee, P; Pyne, SG; Sangdee, A; Seephonkai, P | 1 |
Brun, R; Charman, SA; Charman, WN; Chollet, J; Creek, DJ; Dong, Y; Dorn, A; Koltun, M; Matile, H; Morizzi, J; Padmanilayam, M; Santo Tomas, J; Scheurer, C; Snyder, C; Sriraghavan, K; Tang, Y; Urwyler, H; Vennerstrom, JL; Wang, X; Wittlin, S | 1 |
Greenhouse, B; Joloba, M; Kiggundu, M; Nanyunja, S; Nsobya, SL; Rosenthal, PJ | 1 |
Biagini, GA; Chuawong, P; Fisher, N; Grigg, R; Hasitapan, K; Hunte, C; Kao, WC; Kongkathip, B; Kongkathip, N; Kongsaeree, P; Pradidphol, N; Warman, AJ | 1 |
Fidock, DA; Krishna, S; Scanfeld, D; Uhlemann, AC; Valderramos, SG | 1 |
Fidock, DA; Flannery, EL; Winzeler, EA | 1 |
Amewu, RK; Burrell-Saward, H; Chadwick, J; Hussain, A; Janneh, O; Miguel, C; O'Neill, PM; Panda, S; Rinki, R; Vivas, L; Ward, SA | 1 |
Chowell-Puente, G; Halsey, ES; Jones, S; Kahunu, GM; Kaputu, AK; Likwela, JL; Lucchi, N; Mavoko, HM; Moriarty, LF; Mulopo, PM; Muyembe Tamfum, JJ; Ngoyi, DM; Niang, M; Nkoli, PM; Ntamabyaliro, NY; Plucinski, MM; Rika, JM; Sadou, A; Schmedes, SE; Sompwe, EM; Subramaniam, G; Svigel, SS | 1 |
Banda, S; Blomberg, B; Idro, R; Kühl, MJ; Mukaka, M; Nkosi-Gondwe, T; O Ter Kuile, F; Opoka, RO; Phiri, KS; Robberstad, B | 1 |
Assefa, DG; Makonnen, E; Yismaw, G | 2 |
Ali, AM; Aweeka, F; Dorsey, G; Duvalsaint, M; Huang, L; Hughes, E; Jagannathan, P; Kakuru, A; Kamya, MR; Legac, J; Muhindo, MK; Opira, B; Rosenthal, PJ; Savic, RM; Wallender, E; Whalen, M | 1 |
Aweeka, F; Clark, TD; Dorsey, G; Hughes, E; Jagannathan, P; Kajubi, R; Kakuru, A; Kamya, MR; Ochieng, T; Rosenthal, PJ; Savic, RM; Wallender, E | 1 |
Asua, V; Belay, K; Bosco, A; Bwanika, JB; Ebong, C; Gonahasa, S; Gudoi, S; Halsey, ES; Kamya, MR; Kapisi, J; Kigozi, R; Kyabayinze, D; Lucchi, NW; Moriarty, LF; Mpimbaza, A; Namuganga, JF; Niang, M; Nsobya, SL; Opigo, J; Rubahika, D; Rutazana, D; Sebikaari, G; Souza, SSS; Sserwanga, A; Tibenderana, J; Yeka, A | 1 |
Assefa, DG; Bate, AF; Bekele, E; Makonnen, E; Mebratu, A; Mengistu, N; Molla, W; Sefa, A; Yesmaw, G; Zeleke, ED | 1 |
Deni, I; Dhingra, SK; Eppstein, MJ; Fidock, DA; Gil-Iturbe, E; Hagenah, LM; Kim, J; Mancia, F; Mehta, M; Quick, M; Roepe, PD; Small-Saunders, JL; Vendome, J; Wicht, KJ | 1 |
Baraka, V; Kamugisha, E; Kapesa, A; Kidenya, B; Konje, E; Marwa, K; Mukonzo, J; Swedberg, G | 1 |
Ye, R; Zhang, D; Zhang, Y | 1 |
Grundmann, O; Hernandez Maldonado, J | 1 |
Attaher, O; Bousema, T; Bradley, J; Diallo, M; Dicko, A; Dicko, OM; Drakeley, C; Issiaka, D; Keita, S; Lanke, K; Maguiraga, SO; Mahamar, A; McCall, MBB; Niambele, SM; Sacko, A; Samake, S; Sanogo, K; Sinaba, Y; Smit, MJ; Stone, W; Ter Heine, R; Traore, SF | 1 |
Siahaan, L | 1 |
Campino, S; Clark, TG; Krishna, S; Last, A; Mańko, E; Moss, S | 1 |
Bruschi, F; Fabiani, S; L'Episcopia, M; Mangano, V; Motta, V; Severini, C; Sparavelli, R; Verdenelli, S | 1 |
Baro, B; Bassat, Q; Batty, KT; Karunajeewa, H; Laman, M; Manning, L; Millat-Martínez, P; Mitjà, O; Moore, BR; Page-Sharp, M; Pomat, W; Robinson, LJ; Salman, S | 1 |
Buff, AM; Chebore, W; Desai, M; Kariuki, S; Otieno, K; Owidhi, M; Samuels, AM; Westercamp, N | 1 |
Avery, VM; Duffy, S | 1 |
Clapp, S; Freedman, B; Green, CL; Kirui, JK; Korwa, S; Njuguna, FM; O'Meara, WP; Taylor, SM; Wu, A | 1 |
Albert, I; Bath, J; Fidock, DA; Koo, I; Llinás, M; Mok, S; Okombo, J; Orchard, LM; Owens, E; Qahash, T; Yeo, T | 1 |
Ballo, FI; Barre, YN; Cisse, F; Coulibaly, M; Dama, S; Dao, F; Daou, A; Dara, A; Dara, JN; Dembele, L; Diakite, O; Diallo, N; Djimde, AA; Doumbia, D; Fofana, B; Goita, S; Haidara, AS; Kone, AK; Koumare, S; Niangaly, AB; Ouattara, A; Ouologuem, DT; Sacko, A; Sangare, CPO; Sissoko, S; Sogore, F; Sylla, D; Tandina, F; Tekete, MM; Traore, A | 1 |
Assefa, A; Bekele, W; Chernet, M; Commons, RJ; Etana, K; Gidey, B; Girma, S; Gubae, K; Haile, M; Hailgiorgis, H; Mohammed, H; Sime, H; Solomon, H; Tasew, G; Tollera, G | 1 |
Abera, A; Alemayehu, BH; Anand, A; Assefa, A; Bekele, W; Dilu, D; Etana, K; Ezema, B; Girma, S; Haile, M; Hwang, J; Minta, AA; Mohammed, H; Moriarty, LF; Murphy, M; Sime, H; Solomon, H; Svigel, SS; Tadesse, M; Tadesse, Y; Tasew, G; Teka, H; Woyessa, A; Zhou, Z | 1 |
Abongo, G; Basara, BB; Baseke, J; Bongo, GS; Day, NJP; Dhorda, M; Dondorp, AM; Fanello, C; Kayembe, DK; Maitland, K; Muhindo, R; Mukaka, M; Namayanja, C; Ndjowo, PO; Okalebo, CB; Olupot-Olupot, P; Onyamboko, MA; Onyas, P; Peerawaranun, P; Tarning, J; Taya, C; Taylor, WR; Titin, H; Uyoga, S; Waithira, N; Weere, W; Williams, TN | 1 |
Abuaku, B; Amoako, EO; Asamoah, A; Boateng, P; Duah-Quashie, NO; Koram, KA; Malm, KL; Matrevi, SA; Owusu-Antwi, F; Peprah, NY; Quashie, N | 1 |
Adjei, GO; Ahorhorlu, SY; Alifrangis, M; Duah-Quashie, NO; Dzudzor, B; Hansson, H; Jensen, RW; Kudzi, W; Nartey, ET; Quashie, NB; Wang, CW; Zoiku, F | 1 |
Arinaitwe, E; Kamya, MR; Kiyimba, A; Nankabirwa, J; Obondo, SJ; Ocan, M; Okek, EJ; Ssewanyana, I | 1 |
Akinola, O; Amusan, AI; Ategbero, E; Gbotosho, GO | 1 |
Akala, HM; Amwoma, JG; Andagalu, BM; Chemwor, GC; Cheruiyot, AC; Egbo, TE; Garges, EC; Juma, DW; Juma, JA; Kamau, E; Mwakio, EW; Ogutu, BR; Okoth, RO; Onyango, IA; Opot, BH; Roth, AL; Wakoli, DM; Watson, OJ; Yedah, RA | 1 |
Aina, O; Awolola, ST; Babatunde, S; David, AN; Ekama, SO; Happi, CT; Ijezie, SN; Mohammed, AB; Mokuolu, O; Musa, AZ; Ogbulafor, N; Oguche, S; Okafor, H; Olukosi, AY; Ozor, L; Salako, BL; Uhomoibhi, PE; Wammanda, R | 1 |
Chepngetich, J; Gachie, B; Gathirwa, J; Kiboi, D; Kimani, F; Magoma, G; Muriithi, B; Mwitari, P; Onchieku, N; Thiong'o, K | 1 |
Bailly, J; Bei, AK; Coppée, R; Diallo, MA; Diédhiou, Y; Dièye, B; Diongue, K; Doderer-Lang, C; Fall, A; Garba, MN; Gaye, A; Mama, A; Mbaye, A; Mbaye, AM; Ménard, D; Ndiaye, D; Ndiaye, IM; Ndiaye, T; Thiaw, AB; Tine, A; Yade, MS | 1 |
Arcelia, F; Pasaribu, AP; Yanni, GN | 1 |
Asahi, H; Inoue, SI; Kobayashi, F; Niikura, M; Sendo, F; Wada, A | 1 |
Bradley, J; D'Alessandro, U; Dit Massire Soumare, H; Drakeley, C; Hutchins, H; Jones, RT; Last, AR; Logan, JG; Mabey, D; Martins, C; Nante, EJ; Ndiath, MO; Pretorius, E; Rodrigues, A; Slater, H; Teixeira da Silva, E; Vasileva, H | 1 |
Baraka, V; Francis, F; Geertruyden, JV; Gesase, S; Kyaruzi, E; Lusingu, JPA; Madebe, R; Makenga, G; Minja, DTR; Mtove, G; Nakato, S | 1 |
Asih, PBS; Basri, HH; Bustos, MDG; Charunwatthana, P; Dewayanti, FK; Dondorp, AM; Imwong, M; Permana, DH; Prameswari, HD; Rahmasari, FV; Risandi, R; Rozi, IE; Syafruddin, D; Syahrani, L; Wangsamuda, S | 1 |
D'Alessandro, U; Dabira, ED; Diakite, H; Djimde, M; Dorlo, TP; Erhart, A; González, R; Kabore, B; Kayentao, K; Keita, M; Macuacua, S; Menendez, C; Mens, P; Muhindo, HM; Piqueras, M; Sagara, I; Schallig, H; Sevene, E; Tinto, H; Traore, M; Tshiongo, JK; Vala, A | 1 |
Deng, DW; Li, M; Liu, H; Nie, RH; Wang, HY; Xu, JW; Yin, YJ | 1 |
Arama, C; Beavogui, AH; Dicko, A; Djimde, A; Djimde, M; Fofana, B; Kayentao, K; Mens, PF; Ouedraogo, JB; Sagara, I; Schallig, HD; Sirima, SB; Tshiongo, JK | 1 |
Bamisaiye, A; Basara, BB; Baseke, J; Day, NPJ; Fanello, C; Kayembe, DK; Maitland, K; Muhindo, R; Mukaka, M; Namayanja, C; Ndjowo, PO; Okalebo, CB; Olupot-Olupot, P; Onyamboko, MA; Onyas, P; Taya, C; Taylor, WRJ; Titin, H; Uyoga, S; Were, W; Williams, TN | 1 |
Banda, CG; Kalilani-Phiri, L; Khoo, SH; Lalloo, DG; Macuacua, S; Maculuve, S; Mallewa, J; Mukaka, M; Mwapasa, V; Piqueras, M; Sevene, E; Terlouw, DJ; Vala, A | 1 |
Foguim Tsombeng, F; Gendrot, M; Madamet, M; Pradines, B; Robert, MG | 1 |
Bienvenu, AL; Bonnot, G; Kouakou, YI; Lavoignat, A; Leboucher, G; Picot, S; Tod, M | 1 |
Jiang, T; Krishna, S; Liao, FL; Tu, Y; Wang, J; Xu, C | 1 |
Baum, J; Delves, MJ; Marks, SD; Straschil, U; Witmer, K | 1 |
Adisa, BA; Oludele, OJ; Olufunso, OO | 1 |
Blessborn, D; Byakika-Kibwika, P; Lamorde, M; Ssenyonga, R; Tarning, J | 1 |
Burugu, M; Chege, W; Kimani, F; Matoke-Muhia, D; Muregi, F; Musyoka, KB; Nambati, EA; Omondi, P; Otinga, M; Thiongo, K; Too, E | 1 |
Badjanga, BB; Day, NPJ; Fanello, C; Hoglund, RM; Jackson, NV; Kabedi, C; Kayembe, D; Lee, SJ; McGready, R; Nosten, F; Onyamboko, MA; Tarning, J; Turner, GDH; White, NJ | 1 |
Aye, KH; Bustos, MD; Han, KT; Han, ZY; Lin, K; Markwalter, CF; Moe, M; Myint, MK; Nyunt, MM; Plowe, CV; Rahman, MM; Ringwald, P; Simmons, R; Thi, A | 1 |
Aweeka, F; Huang, L; Hughes, E; Kajubi, R; Mwebaza, N; Mwima, MW; Nguyen, V; Nyunt, MM; Orukan, F; Parikh, S | 1 |
Anderson, TJC; Button-Simons, KA; Cassady, Z; Checkley, LA; Davis, SZ; Ferdig, MT; Foster, GJ; McDew-White, M; Nosten, FH; Shoue, DA; Sievert, MAC; Singh, PP; Vendrely, KM | 1 |
Adhikari, B; Cheah, PY; Chotivanich, K; Cobelens, F; Davoeung, C; Day, NPJ; Dhorda, M; Dondorp, AM; Hanboonkunupakarn, B; Hien, TT; Imwong, M; Jittmala, P; Kajeechiwa, L; Landier, J; Lwin, KM; Mayxay, M; Mukaka, M; Newton, PN; Nguon, C; Nguyen, TN; Nosten, FH; Nosten, S; Parker, DM; Peerawaranun, P; Peto, TJ; Phommasone, K; Pongvongsa, T; Promnarate, C; Proux, S; Pukrittayakamee, S; Rekol, H; Thwaites, GE; Thwin, MM; Tripura, R; van Leth, F; von Seidlein, L; White, NJ; Wiladphaingern, J | 1 |
Boonhok, R; Cabrera, M; Cao, Y; Cui, L; Liang, X; Mbenda, HGN; Miao, J; Min, H; Qin, J; Siddiqui, FA; Wang, M; Zhu, X | 1 |
Amaratunga, C; Amato, R; Anvikar, AR; Ashley, E; Baidya, S; Behera, PK; Callery, JJ; Chau, NH; Cheah, PY; Chotivanich, K; Chutasmit, K; Day, NPJ; Dhorda, M; Dondorp, AM; Fairhurst, RM; Faiz, A; Fanello, C; Gantait, K; Ghosh, T; Gonçalves, S; Grobusch, MP; Hanboonkunupakarn, B; Heaton, J; Hien, TT; Hlaing, TM; Hoa, NT; Hoglund, RM; Huy, R; Imwong, M; Jacob, CG; Jittamala, P; Kaewmok, W; Kwiatkowski, DP; Lek, D; Lin, K; Mao, S; Maude, RJ; Mayxay, M; Miotto, O; Mohanty, AK; Mukaka, M; Newton, PN; Onyamboko, M; Oun, S; Pearson, RD; Peto, TJ; Pukrittayakamee, S; Pyae Phyo, A; Runcharern, R; Saelow, C; Satpathi, P; Satpathi, S; Smithuis, F; Sovann, Y; Sreng, S; Suon, S; Tarning, J; Thanh, NV; Thant, M; Thuy-Nhien, NT; Tripura, A; Tripura, R; Ul Islam, A; Valecha, N; van der Pluijm, RW; van Vugt, M; von Seidlein, L; Waithira, N; White, NJ; Winterberg, M; Woodrow, CJ; Yen, S | 1 |
Desai, MR; Hamel, MJ; Kachur, SP; Kariuki, S; Lindblade, KA; Odero, NA; Odongo, W; Otieno, K; Samuels, AM; Shi, YP; Williamson, J | 1 |
Achan, J; Arinaitwe, E; Bigira, V; Dorsey, G; Gasasira, A; Havlir, D; Jagannathan, P; Kakuru, A; Kamya, MR; Kapisi, J; Muhindo, M; Nankabirwa, JI; Natureeba, P; Rek, J; Rodriguez-Barraquer, I; Rosenthal, PJ; Wanzira, H | 1 |
Duong, NTT; Duong, TT; Erhart, A; Guetens, P; Hien, NTT; Hieu, NL; Huan, RM; Kattenberg, JH; Mai, TT; Ngoc, NTH; Phuc, BQ; Rosanas-Urgell, A; Rovira-Vallbona, E; Van Hong, N; Xa, NX | 1 |
Badiane, AS; Dème, AB; Diallo, I; Diallo, MA; Dieye, B; Diongue, K; Gomis, JF; Ndiaye, D; Ndiaye, M; Ndiaye, YD; Seck, MC; Sow, D; Sy, M; Sy, SA; Yade, MS | 1 |
Anvikar, AR; Ashley, EA; Chandramohan, D; Cohee, LM; D'Alessandro, U; Genton, B; Gilder, ME; Guérin, PJ; Juma, E; Kalilani-Phiri, L; Kennon, K; Kuepfer, I; Laufer, MK; Lwin, KM; Mansoor, R; McGready, R; Meshnick, SR; Mosha, D; Mwapasa, V; Mwebaza, N; Nambozi, M; Ndiaye, JA; Nosten, F; Nyunt, M; Ogutu, B; Parikh, S; Paw, MK; Phyo, AP; Pimanpanarak, M; Piola, P; Rijken, MJ; Saito, M; Sriprawat, K; Stepniewska, K; Tagbor, HK; Tarning, J; Tinto, H; Valéa, I; Valecha, N; White, NJ; Wiladphaingern, J | 1 |
Bah, S; Dabitao, D; Dama, S; Diakité, M; Diakité, SAS; Doumbia, S; Doumbouya, M; Guindo, MA; Keita, B; Konaté, DS; Sangaré, M; Sanogo, I; Traoré, K | 1 |
Chiyende, E; Chizema Kawesha, E; Earle, D; Eisele, TP; Finn, TP; Hamainza, B; Jennings, T; Miller, JM; Sikombe, C; Silumbe, K; Steketee, RW | 1 |
Bennett, A; Bridges, DJ; Chishimba, S; Eisele, TP; Finn, TP; Hamainza, B; Lungu, C; Mambwe, B; Miller, JM; Mulube, C; Mwenda, MC; Porter, TR; Silumbe, K; Slutsker, L; Steketee, RW; Yukich, JO | 1 |
Chizema Kawesha, E; Miller, JM; Steketee, RW | 1 |
Bennett, A; Conner, RO; Eisele, TP; Finn, TP; Hamainza, B; Keating, J; Larson, BA; Miller, JM; Porter, TR; Scott, C; Silumbe, K; Steketee, RW; Yukich, JO | 1 |
Bennett, A; Chalwe, V; Chizema Kawesha, E; Conner, RO; Earle, D; Eisele, TP; Finn, TP; Hamainza, B; Kamuliwo, M; Keating, J; Kooma, E; Miller, JM; Moonga, H; Porter, TR; Schneider, K; Silumbe, K; Slutsker, L; Steketee, RW; Yukich, JO | 1 |
Bennett, A; Chalwe, V; Eisele, TP; Finn, TP; Hamainza, B; Keating, J; Kooma, E; Miller, JM; Moonga, H; Porter, TR; Silumbe, K; Steketee, RW; Yukich, JO | 1 |
Bennett, A; Chizema Kawesha, E; Conner, RO; Eisele, TP; Finn, TP; Hamainza, B; Keating, J; Lungu, C; Miller, JM; Porter, TR; Silumbe, K; Steketee, RW; Yukich, JO | 1 |
Chizema Kawesha, E; Eisele, TP; Fraser, MS; Lewis, MT; Miller, JM; Slutsker, L | 1 |
Ba, A; Ba, M; Ba, S; Cissé, B; Cissé, M; Conner, RO; Dieye, Y; Diop, M; Doucouré, E; Earle, D; Faye, F; Guinot, P; Guinovart, C; Hainsworth, M; Schneider, K; Sene, D; Steketee, RW; Sy, MD; Tall, A; Thiam, T | 1 |
Abbasi, S; Abd El-Wahab, A; Abdallah, M; Abebe, G; Aca-Aca, G; Adama, S; Adefegha, SA; Adidigue-Ndiome, R; Adiseshaiah, P; Adrario, E; Aghajanian, C; Agnese, W; Ahmad, A; Ahmad, I; Ahmed, MFE; Akcay, OF; Akinmoladun, AC; Akutagawa, T; Alakavuklar, MA; Álava-Rabasa, S; Albaladejo-Florín, MJ; Alexandra, AJE; Alfawares, R; Alferiev, IS; Alghamdi, HS; Ali, I; Allard, B; Allen, JD; Almada, E; Alobaid, A; Alonso, GL; Alqahtani, YS; Alqarawi, W; Alsaleh, H; Alyami, BA; Amaral, BPD; Amaro, JT; Amin, SAW; Amodio, E; Amoo, ZA; Andia Biraro, I; Angiolella, L; Anheyer, D; Anlay, DZ; Annex, BH; Antonio-Aguirre, B; Apple, S; Arbuznikov, AV; Arinsoy, T; Armstrong, DK; Ash, S; Aslam, M; Asrie, F; Astur, DC; Atzrodt, J; Au, DW; Aucoin, M; Auerbach, EJ; Azarian, S; Ba, D; Bai, Z; Baisch, PRM; Balkissou, AD; Baltzopoulos, V; Banaszewski, M; Banerjee, S; Bao, Y; Baradwan, A; Barandika, JF; Barger, PM; Barion, MRL; Barrett, CD; Basudan, AM; Baur, LE; Baz-Rodríguez, SA; Beamer, P; Beaulant, A; Becker, DF; Beckers, C; Bedel, J; Bedlack, R; Bermúdez de Castro, JM; Berry, JD; Berthier, C; Bhattacharya, D; Biadgo, B; Bianco, G; Bianco, M; Bibi, S; Bigliardi, AP; Billheimer, D; Birnie, DH; Biswas, K; Blair, HC; Bognetti, P; Bolan, PJ; Bolla, JR; Bolze, A; Bonnaillie, P; Borlimi, R; Bórquez, J; Bottari, NB; Boulleys-Nana, JR; Brighetti, G; Brodeur, GM; Budnyak, T; Budnyk, S; Bukirwa, VD; Bulman, DM; Burm, R; Busman-Sahay, K; Butcher, TW; Cai, C; Cai, H; Cai, L; Cairati, M; Calvano, CD; Camacho-Ordóñez, A; Camela, E; Cameron, T; Campbell, BS; Cansian, RL; Cao, Y; Caporale, AS; Carciofi, AC; Cardozo, V; Carè, J; Carlos, AF; Carozza, R; Carroll, CJW; Carsetti, A; Carubelli, V; Casarotta, E; Casas, M; Caselli, G; Castillo-Lora, J; Cataldi, TRI; Cavalcante, ELB; Cavaleiro, A; Cayci, Z; Cebrián-Tarancón, C; Cedrone, E; Cella, D; Cereda, C; Ceretti, A; Ceroni, M; Cha, YH; Chai, X; Chang, EF; Chang, TS; Chanteux, H; Chao, M; Chaplin, BP; Chaturvedi, S; Chaturvedi, V; Chaudhary, DK; Chen, A; Chen, C; Chen, HY; Chen, J; 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Bassat, Q; Menéndez, C | 1 |
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Buathong, N; Cantilena, L; Chann, S; Haigney, M; Ittiverakul, M; Kodchakorn, C; Kuntawunginn, W; Lanteri, C; Lon, C; Manning, J; Milner, E; Pann, ST; Prom, S; Saunders, D; So, M; Sok, S; Spring, M; Sriwichai, S; Ta-Aksorn, W; Vanachayangkul, P; Wojnarski, M; Youdaline, T | 1 |
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Bergstrand, M; Karlsson, MO; Nosten, F; Permala, J; Tarning, J; White, NJ | 1 |
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Le Thi, DT; Le, NH; Na-Bangchang, K; Nguyen, CH; Phan Thi, D | 1 |
Christophel, E; Hu, XM; Lin, SG; Liu, J; Meng, F; Wang, GZ; Wang, SQ; Zeng, LH | 1 |
Day, NP; Dondorp, AM; Hanpithakpong, W; Kamanikom, B; Lindegardh, N; McGready, R; Nosten, F; Singhasivanon, P; Socheat, D; White, NJ; Yi, P | 1 |
Kager, PA; Mens, PF; Omar, SA; Sawa, P; Schallig, HD; van Amsterdam, SM; Versteeg, I | 1 |
Davis, TM; Gomorrai, PS; Griffin, S; Ilett, KF; Karunajeewa, HA; Kotab, K; Lautu, D; Law, I; Lin, E; Mueller, I; Oa, O; Page-Sharp, M; Salman, S; Senn, M; Siba, P; Suano, P; Tarongka, N; Ura, A; Wong, R | 1 |
Chavchich, M; Dai, B; Edstein, MD; Phong, NC; Shanks, GD; Thanh, NX; Thien, NX; Trung, TN | 1 |
Bandyopadhyay, N; Duparc, S; Kirby, PL; Miller, AK; Ward, SA; Winstanley, PA; Wootton, DG | 1 |
Basco, LK; Ringwald, P; Tahar, R | 1 |
Song, JP; Tan, B; Trung, TN; Van Phuc, D | 1 |
Srinivas, NR | 1 |
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Ashley, EA; D'Alessandro, U; Dorsey, G; Janssens, B; Karema, C; Mayxay, M; Newton, P; Nosten, F; Singhasivanon, P; Smithuis, F; Stepniewska, K; White, NJ; Zwang, J | 1 |
Arinaitwe, E; Dorsey, G; Greenhouse, B; Homsy, J; Kakuru, A; Kalamya, J; Kamya, MR; Rosenthal, PJ; Sandison, TG; Tappero, J; Vora, N; Wanzira, H | 1 |
Douglas, NM; Price, RN | 1 |
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Giha, HA | 1 |
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Annerberg, A; Ashley, EA; Lindegardh, N; McGready, R; Nosten, F; Phaiphun, L; Singhasivanon, P; Stepniewska, K; Tarning, J; White, NJ | 1 |
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Chaponda, M; D'Alessandro, U; Hachizovu, S; Mukwamataba, D; Mulenga, M; Nambozi, M; Ubben, D; Van Geertruyden, JP | 1 |
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Dharia, NV; Eastman, RT; Fidock, DA; Winzeler, EA | 1 |
Björkman, A; Ferreira, PE; Gil, JP; Jörnhagen, L; Kone, A; Malmberg, M; Nosten, F; Petzold, M; Schmidt, BA; Veiga, MI | 1 |
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Abu-Bakar, N; Bottova, I; Crespo-Ortiz, MP; Kenny, S; Klonis, N; Rosenthal, PJ; Tilley, L | 1 |
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Davis, TM; Hwaiwhanje, I; Karunajeewa, HA; Laman, M; Manning, L; Morep, N; Mueller, I; Page-Sharp, M; Salman, S; Siba, P | 1 |
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Li, CF; Liu, H; Nie, RH; Wang, HY; Yang, HL; Zhang, J | 1 |
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Keating, GM | 1 |
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Charman, SA; Gamo-Benito, J; Humberstone, A; Jamsen, KM; McCaw, J; Moehrle, J; Price, RN; Simpson, JA; Smith, K; Zaloumis, S | 1 |
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Dahlan, MS; Hawley, WA; Kosasih, A; Kusriastuti, R; Lobo, NF; Suprijanto, S; Sutanto, I; Syafruddin, D; Ter Kuile, FO | 1 |
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Graninger, W; Kremsner, PG; Noedl, H; Ramharter, M; Wernsdorfer, WH; Winkler, H; Winkler, S | 1 |
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Binh, TQ; de Vries, PJ; Giao, PT; Hung, le Q; Kager, PA; Nam, NV | 1 |
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Kongthaisong, M; Mungthin, M; Na-Bangchang, K; Sinchaipanid, N; Tan-Ariya, P | 1 |
Chalearmrult, K; Krudsood, S; Li, Q; Looareesuwan, S; Lugt, CB; Milhous, WK; Vannaphan, S; Wilairatana, P | 1 |
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Karbwang, J; Na-Bangchang, K; Thanavibul, A; Tippawangkosol, P | 1 |
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Chalermrut, K; Kano, S; Krudsood, S; Looareesuwan, S; Pengruksa, C; Phongtananant, S; Silachamroon, U; Srivilairit, S; Tangpukdee, N; Thanachartwet, W; Wilairatana, P | 1 |
Cho, T; Gilveray, G; Looareesuwan, S; McGready, R; Nosten, F; Stepniewska, K; Ward, SA; White, NJ | 1 |
D'Alessandro, U; Fanello, CI; Karema, C; Ngamije, D; van Doren, W; van Geertruyden, JP; van Overmeir, C | 1 |
Duffy, PE; Mutabingwa, TK | 1 |
Ashley, E; Aye, KZ; Barends, M; Htet, L; Kyaw, MK; Lindegardh, N; Lwin, S; Phe, O; Singtoroj, T; Smithuis, F; Stepniewska, K; White, NJ | 1 |
Barends, M; Keola, S; Khanthavong, M; Lindegårdh, N; Mayxay, M; Newton, PN; Phetsouvanh, R; Phompida, S; Pongvongsa, T; Stepniewska, K; Thongpraseuth, V; White, NJ | 1 |
Ashley, EA; La, Y; Lindegardh, N; McGready, R; Nosten, F; Singhasivanon, P; Stepniewska, K; White, NJ | 1 |
Barnes, KI; Chierakul, W; Evans, AC; Newton, PN; Ruangveerayuth, R; Smith, PJ; White, NJ | 1 |
Atemnkeng, MA; De Cock, K; Plaizier-Vercammen, J | 1 |
Ayede, I; Dada-Adegbola, HO; Fadero, FF; Falade, AG; Falade, CO; Gbotosho, GO; Happi, CT; Oduola, AM; Salako, LA | 1 |
Anderson, T; Barends, M; Brockman, A; Jaidee, A; Mayxay, M; Nair, S; Newton, PN; Phetsouvanh, R; Phompida, S; Pongvongsa, T; Sudimack, D; White, NJ | 1 |
Ashley, EA; Brockman, A; Chan, S; Goubert, L; Janssens, B; Nong, S; Socheat, D; Uong, S; Van Damme, W; van Herp, M | 1 |
Anstey, NM; Ebsworth, EP; Kenangalem, E; Laihad, F; Maristela, R; Price, RN; Ratcliff, A; Siswantoro, H; Tjitra, E; Wuwung, RM | 1 |
Anstey, NM; Ebsworth, EP; Hasugian, AR; Kenangalem, E; Laihad, F; Maristela, R; Penttinen, PM; Price, RN; Purba, HL; Tjitra, E; Wuwung, RM | 1 |
Hung, le N; Hung, NC; Na-Bangchang, K; Thuy, le TD | 1 |
Chong, MT; Danh, PT; Diem Thuy, le T; Hung, le N; Na-Bangchang, K; Van Binh, N; Van Thang, N | 1 |
Ashley, EA; Day, NP; Myint, HY; Nosten, F; White, NJ | 1 |
Ashley, EA; Hae, R; La, Y; Mytton, OT; Nosten, F; Peto, L; Price, RN; Singhasivanon, P; White, NJ | 1 |
Batty, KT; Davis, TM; Ilett, KF; Karunajeewa, HA; Lammey, J; Law, I; Lin, E; Mueller, I; Page-Sharp, M; Siba, P | 1 |
Bernasconi, A; Casapia, M; D'Alessandro, U; Delgado, C; Erhart, A; Fanello, C; Gamboa, D; Grande, T; Llanos-Cuentas, A; Torres, K | 1 |
Akther, S; Fukuda, M; Haque, R; Khan, WA; Marma, AS; Noedl, H; Starzengruber, P; Thriemer, K; Vossen, MG | 2 |
Chaijaroenkul, W; Muhamad, P; Na-Bangchang, K; Pruktal, P | 1 |
Ashley, EA; Ashton, M; Day, NP; Lindegardh, N; McGready, R; Nosten, F; Phaiphun, L; Stepniewska, K; Tarning, J; White, NJ | 1 |
Barends, M; Boel, ME; McGready, R; Nosten, F; Pimanpanarak, M; Proux, S; Rijken, MJ; Singhasivanon, P | 1 |
Anstey, NM; Fobia, W; Kenangalem, E; Lampah, DA; McGready, R; Poespoprodjo, JR; Price, RN; Seal, A; Sugiarto, P; Tjitra, E; Warikar, N | 1 |
Fu, LC; Guo, XB; Jian, HX; Li, GQ; Wang, XH | 1 |
Edwards, G; Karbwang, J; Na Bangchang, K; Sukontason, K; Thanavibul, A; Thomas, CG; Ward, SA | 1 |
Guo, XB | 1 |
Anh, TK; Batty, KT; Binh, TQ; Davis, TM; Ilett, KF; Thu, LT | 1 |
Kraisintu, K; Looareesuwan, S; Pitisuttithum, P; Vanijanonta, S; Viravan, C; Wilairatana, P | 1 |
Davis, TM; Johnston, WA; Manning, LS; Skinner, TS | 1 |
Batty, KT; Binh, TQ; Davis, TM; Hung, NC; Ilett, KF; Kim, NV; Mai, TX; Powell, SM; Thien, HV; Thu, LT; Tien, NP | 1 |
Congpoung, K; Karbwang, J; Na-Bangchang, K; Thanavibul, A; Ubalee, R | 1 |
Benakis, A; Halpaap, B; Kremsner, PG; Ndjave, M; Paris, M | 1 |
Congpuong, K; Karbwang, J; Molunto, P; Na-Bangchang, K; Thanavibul, A; Wattanakoon, Y | 1 |
Karbwang, J; Molunto, P; Na-Bangchang, K; Thanavibul, A | 1 |
Harinasuta, T; Karbwang, J; Na-Bangchang, K; Rimchala, W; Sukontason, K; Tin, T | 1 |
Chalermrut, K; Chanthavanich, P; Kraisintu, K; Krudsood, S; Looareesuwan, S; Phisalaphong, C; Singhasivanon, P; Treeprasertsuk, S; Wilairatana, P | 1 |
de Vries, PJ; Ha, LD; Kager, PA; Khanh, NX; Koopmans, R; van Boxtel, CJ | 1 |
Li, Y; Wu, YL | 1 |
Le Bras, J | 1 |
Looareesuwan, S; Wilairatana, P | 1 |
Ding, Y; Qi, Z; Xu, C | 1 |
Cheng-Qi, S; Mull, R; Qing, JX; van Agtmael, MA; van Boxtel, CJ | 1 |
Chaovanakawee, S; Karbwang, J; Na-Bangchang, K; Saenglertsilapachai, S; Tippanangkosol, P; Ubalee, R | 1 |
Duraisingh, MT; Jones, P; Pinder, M; Sambou, I; von Seidlein, L; Warhurst, DC | 1 |
Karbwang, J; Na-Bangchang, K; Palacios, PA; Saengtertsilapachai, S; Ubalee, R; Wernsdorfer, WH | 1 |
Chen, PQ; Fu, LC; Guo, XB; Jian, HX; Li, GQ; Wang, XH | 1 |
Batty, KT; Binh, TQ; Davis, TM; Hung, NC; Ilett, KF; Phuong, HL; Phuong, VD; Powell, SM; Thien, HV | 1 |
Maggs, JL; O'Neill, PM; Park, BK; Scheinmann, F; Stachulski, AV | 1 |
Batty, KT; Binh, TQ; Davis, TM; Hung, NC; Ilett, KF; Phuöng, HL; Phuong, VD; Powell, SM; Thien, HV; Thu, LT | 1 |
Micha, ST; Wang, W; Yang, W | 1 |
Brewer, TG; Eamsila, C; Jongsakul, K; Keeratithakul, G; Kyle, DE; Li, Q; Luesutthiviboon, L; Sirisopana, N; Teja-Isavadharm, P; Watt, G | 1 |
Batty, KT; Binh, TQ; Davis, TM; Hung, NC; Ilett, KF; Phuong, HL; Powell, SM; Thu, le TA | 1 |
Looareesuwan, S; Newton, PN; Nosten, F; Rasameesoroj, M; Ruangveerayuth, R; Siriyanonda, D; Slight, T; Suputtamongkol, Y; Teerapong, P; Teja-Isavadharm, P; van Vugt, M; White, NJ | 1 |
28 review(s) available for artenimol and Plasmodium falciparum Malaria
Article | Year |
---|---|
Using genetic methods to define the targets of compounds with antimalarial activity.
Topics: Animals; Anopheles; Antimalarials; Drug Resistance; Genetic Association Studies; Genome, Protozoan; Humans; Malaria, Falciparum; Molecular Targeted Therapy; Plasmodium falciparum | 2013 |
Comparative effect of dihydroartemisinin-piperaquine and artemether-lumefantrine on gametocyte clearance and haemoglobin recovery in children with uncomplicated Plasmodium falciparum malaria in Africa: a systematic review and meta-analysis of randomized c
Topics: Africa; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Drug Combinations; Fluorenes; Hemoglobins; Humans; Malaria, Falciparum; Plasmodium falciparum; Quinolines; Randomized Controlled Trials as Topic | 2021 |
Safety of dihydroartemisinin-piperaquine versus artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria among children in Africa: a systematic review and meta-analysis of randomized control trials.
Topics: Adolescent; Africa; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Child, Preschool; Drug Combinations; Humans; Infant; Malaria, Falciparum; Plasmodium falciparum; Quinolines; Randomized Controlled Trials as Topic | 2022 |
Therapeutic efficacy of artemether-lumefantrine, artesunate-amodiaquine and dihydroartemisinin-piperaquine in the treatment of uncomplicated Plasmodium falciparum malaria in Sub-Saharan Africa: A systematic review and meta-analysis.
Topics: Africa South of the Sahara; Amodiaquine; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Drug Combinations; Ethanolamines; Humans; Malaria; Malaria, Falciparum; Piperazines; Plasmodium falciparum; Quinolines | 2022 |
Drug-Drug Interactions of Artemisinin-Based Combination Therapies in Malaria Treatment: A Narrative Review of the Literature.
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Humans; Malaria; Malaria, Falciparum | 2022 |
How has mass drug administration with dihydroartemisinin-piperaquine impacted molecular markers of drug resistance? A systematic review.
Topics: Antimalarials; Artemisinins; Biomarkers; Drug Resistance; Humans; Malaria, Falciparum; Mass Drug Administration; Piperazines; Plasmodium falciparum; Quinolines | 2022 |
Therapeutic efficacy of dihydroartemisinin-piperaquine combination for the treatment of uncomplicated malaria in Ghana.
Topics: Antimalarials; Child; Drug Combinations; Ghana; Humans; Malaria; Malaria, Falciparum; Parasitemia; Treatment Outcome | 2022 |
Systematic review of artesunate pharmacokinetics: Implication for treatment of resistant malaria.
Topics: Administration, Intravenous; Administration, Oral; Antimalarials; Artemisinins; Artesunate; Asia, Southeastern; Drug Monitoring; Drug Resistance; Humans; Malaria; Malaria, Falciparum | 2019 |
Efficacy and tolerability of artemisinin-based and quinine-based treatments for uncomplicated falciparum malaria in pregnancy: a systematic review and individual patient data meta-analysis.
Topics: Amodiaquine; Anti-Bacterial Agents; Antimalarials; Artemisinins; Artesunate; Atovaquone; Clindamycin; Drug Combinations; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Mefloquine; Pregnancy; Pregnancy Complications, Parasitic; Proguanil; Pyrimethamine; Quinine; Quinolines; Sulfadoxine | 2020 |
Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain; Acyclic Monoterpenes; Adenine Nucleotides; Adhesins, Escherichia coli; Adipocytes; Adipocytes, Brown; Adipogenesis; Administration, Inhalation; Administration, Oral; Adrenal Cortex Hormones; Adsorption; Adult; Aeromonas hydrophila; Africa; Aged; Aged, 80 and over; Agrobacterium tumefaciens; Air; Air Pollutants; Air Pollution; Air Pollution, Indoor; Algorithms; Alkaloids; Alkynes; Allosteric Regulation; Amines; Amino Acid Sequence; Amino Acids; Amino Acids, Branched-Chain; Aminoisobutyric Acids; Aminopyridines; Amyotrophic Lateral Sclerosis; Anaerobic Threshold; Angiography; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animal Distribution; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Ankle Joint; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Inflammatory Agents; Antibodies, Bacterial; Antifungal Agents; Antimalarials; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antioxidants; Antiretroviral Therapy, Highly Active; Antiviral Agents; Aotidae; Apelin; Apoptosis; Arabidopsis Proteins; Argentina; Arginine; Artemisinins; Arthritis, Experimental; Arthritis, Rheumatoid; Arthroscopy; Aspergillus; Aspergillus niger; Asteraceae; Asthma; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; Auditory Cortex; Autoantibodies; Autophagy; Bacteria; Bacterial Infections; Bacterial Proteins; Bacterial Typing Techniques; Base Composition; Base Sequence; Basketball; Beclin-1; Benzhydryl Compounds; Benzimidazoles; Benzo(a)pyrene; Benzofurans; Benzoxazines; Bereavement; beta Catenin; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Betacoronavirus; Betaine; Binding Sites; Biofilms; Biological Assay; Biological Availability; Biological Evolution; Biomarkers; Biomechanical Phenomena; Biopolymers; Biopsy; Bismuth; Blood Glucose; Blood Platelets; Blood Pressure; Body Composition; Body Weight; Bone Marrow; Bone Marrow Cells; Bone Regeneration; Boron; Botrytis; Brain Ischemia; Brain Neoplasms; Brain-Derived Neurotrophic Factor; Brazil; Breast Neoplasms; Breath Tests; Bronchoalveolar Lavage Fluid; Burkholderia; C-Reactive Protein; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Calcification, Physiologic; Calcium; Calcium Signaling; Calorimetry, Differential Scanning; Cameroon; Camptothecin; Candida; Candida albicans; Capillaries; Carbapenem-Resistant Enterobacteriaceae; Carbapenems; Carbohydrate Conformation; Carbon; Carbon Dioxide; Carbon Isotopes; Carcinoma, Ovarian Epithelial; Cardiac Output; Cardiomyopathy, Hypertrophic; Cardiotonic Agents; Cardiovascular Diseases; Caregivers; Carps; Case-Control Studies; Catalase; Catalysis; Cats; CD4 Lymphocyte Count; Cell Culture Techniques; Cell Differentiation; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Proliferation; Cell Survival; Cells, Cultured; Cellulose; Centrosome; Ceratopogonidae; Chickens; Child; China; Cholera Toxin; Choline; Cholinesterases; Chromatography, High Pressure Liquid; Chromatography, Liquid; Chromatography, Micellar Electrokinetic Capillary; Chromatography, Reverse-Phase; Chronic Disease; Cinnamates; Cities; Citrates; Climate Change; Clinical Trials, Phase III as Topic; Coal; Coal Mining; Cohort Studies; Coinfection; Colchicine; Colony Count, Microbial; Colorectal Neoplasms; Coloring Agents; Common Cold; Complement Factor H; Computational Biology; Computer Simulation; Continuous Positive Airway Pressure; Contrast Media; Coordination Complexes; Coronary Artery Bypass; Coronavirus 3C Proteases; Coronavirus Infections; Coronavirus Protease Inhibitors; Corynebacterium glutamicum; Cosmetics; COVID-19; Creatinine; Cross-Sectional Studies; Crotonates; Crystallography, X-Ray; Cues; Culicidae; Culture Media; Curcuma; Cyclopentanes; Cyclopropanes; Cymbopogon; Cystine; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C19 Inhibitors; Cytokines; Databases, Genetic; Death; Dendritic Cells; Density Functional Theory; Depsides; Diabetes Mellitus, Type 2; Diamond; Diarylheptanoids; Dibenzofurans; Dibenzofurans, Polychlorinated; Diclofenac; Diet; Dietary Carbohydrates; Dietary Supplements; Diffusion Magnetic Resonance Imaging; Dioxins; Diphenylamine; Disease Outbreaks; Disease Susceptibility; Disulfides; Dithiothreitol; Dizocilpine Maleate; DNA Methylation; DNA-Binding Proteins; DNA, Bacterial; Dogs; Dose-Response Relationship, Drug; Double-Blind Method; Doublecortin Protein; Drosophila melanogaster; Droughts; Drug Carriers; Drug Combinations; Drug Delivery Systems; Drug Liberation; Drug Resistance; Drug Resistance, Bacterial; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Dust; Dynactin Complex; Dysferlin; Echo-Planar Imaging; Echocardiography; Edaravone; Egypt; Elasticity; Electrodes; Electrolytes; Emodin; Emtricitabine; Endometriosis; Endothelium, Vascular; Endotoxins; Energy Metabolism; Energy Transfer; Enterobacteriaceae; Enterococcus faecalis; Enterotoxigenic Escherichia coli; Environmental Monitoring; Enzyme Inhibitors; Epidemiologic Factors; Epigenesis, Genetic; Erythrocytes; Escherichia coli; Escherichia coli Infections; Escherichia coli Vaccines; Esophageal Neoplasms; Esophagectomy; Esophagogastric Junction; Esterases; Esterification; Ethanol; Ethiopia; Ethnicity; Eucalyptus; Evidence-Based Practice; Exercise; Exercise Tolerance; Extracorporeal Membrane Oxygenation; Family; Fatty Acids; Feedback; Female; Ferric Compounds; Fibrin Fibrinogen Degradation Products; Filtration; Fish Diseases; Flavonoids; Flavonols; Fluorodeoxyglucose F18; Follow-Up Studies; Food Microbiology; Food Preservation; Forests; Fossils; Free Radical Scavengers; Freund's Adjuvant; Fruit; Fungi; Gallium; Gender Identity; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Plant; Gene Knockdown Techniques; Genes, Bacterial; Genes, Plant; Genetic Predisposition to Disease; Genitalia; Genotype; Glomerulonephritis, IGA; Glottis; Glucocorticoids; Glucose; Glucuronides; Glutathione Transferase; Glycogen Synthase Kinase 3 beta; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Grassland; Guinea Pigs; Half-Life; Head Kidney; Heart Atria; Heart Rate; Heart Septum; HEK293 Cells; Hematopoietic Stem Cells; Hemodynamics; Hep G2 Cells; Hepacivirus; Hepatitis C; Hepatitis C, Chronic; Hepatocytes; Hesperidin; High-Frequency Ventilation; High-Temperature Requirement A Serine Peptidase 1; Hippocampus; Hirudins; History, 20th Century; History, 21st Century; HIV Infections; Homeostasis; Hominidae; Housing, Animal; Humans; Hydrocarbons, Brominated; Hydrogen Bonding; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxybutyrates; Hydroxyl Radical; Hypertension; Hypothyroidism; Image Interpretation, Computer-Assisted; Immunoconjugates; Immunogenic Cell Death; Indoles; Infant, Newborn; Infant, Premature; Infarction, Middle Cerebral Artery; Inflammation; Inflammation Mediators; Infrared Rays; Inhibitory Concentration 50; Injections, Intravenous; Interferon-gamma; Interleukin-23; Interleukin-4; Interleukin-6; Intermediate Filaments; Intermittent Claudication; Intestine, Small; Iridoid Glucosides; Iridoids; Iron; Isomerism; Isotope Labeling; Isoxazoles; Itraconazole; Kelch-Like ECH-Associated Protein 1; Ketoprofen; Kidney Failure, Chronic; Kinetics; Klebsiella pneumoniae; Lactams, Macrocyclic; Lactobacillus; Lactulose; Lakes; Lamivudine; Laparoscopy; Laparotomy; Laryngoscopy; Leucine; Limit of Detection; Linear Models; Lipid A; Lipopolysaccharides; Listeria monocytogenes; Liver; Liver Cirrhosis; Logistic Models; Longitudinal Studies; Losartan; Low Back Pain; Lung; Lupinus; Lupus Erythematosus, Systemic; Machine Learning; Macular Degeneration; Madin Darby Canine Kidney Cells; Magnetic Phenomena; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Magnetics; Malaria, Falciparum; Male; Mannans; MAP Kinase Signaling System; Mass Spectrometry; Melatonin; Membrane Glycoproteins; Membrane Proteins; Meniscectomy; Menisci, Tibial; Mephenytoin; Mesenchymal Stem Cells; Metal Nanoparticles; Metal-Organic Frameworks; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; Mice, Obese; Mice, Transgenic; Microbial Sensitivity Tests; Microcirculation; MicroRNAs; Microscopy, Video; Microtubules; Microvascular Density; Microwaves; Middle Aged; Minimally Invasive Surgical Procedures; Models, Animal; Models, Biological; Models, Molecular; Models, Theoretical; Molecular Docking Simulation; Molecular Structure; Molecular Weight; Morus; Mouth Floor; Multicenter Studies as Topic; Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting; Muscle, Skeletal; Myocardial Ischemia; Myocardium; NAD; NADP; Nanocomposites; Nanoparticles; Naphthols; Nasal Lavage Fluid; Nasal Mucosa; Neisseria meningitidis; Neoadjuvant Therapy; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Neoplasms, Experimental; Neural Stem Cells; Neuroblastoma; Neurofilament Proteins; Neurogenesis; Neurons; New York; NF-E2-Related Factor 2; NF-kappa B; Nicotine; Nitriles; Nitrogen; Nitrogen Fixation; North America; Observer Variation; Occupational Exposure; Ochrobactrum; Oils, Volatile; Olea; Oligosaccharides; Omeprazole; Open Field Test; Optimism; Oregon; Oryzias; Osmolar Concentration; Osteoarthritis; Osteoblasts; Osteogenesis; Ovarian Neoplasms; Ovariectomy; Oxadiazoles; Oxidation-Reduction; Oxidative Stress; Oxygen; Ozone; p38 Mitogen-Activated Protein Kinases; Pakistan; Pandemics; Particle Size; Particulate Matter; Patient-Centered Care; Pelargonium; Peptides; Perception; Peripheral Arterial Disease; Peroxides; Pets; Pharmaceutical Preparations; Pharmacogenetics; Phenobarbital; Phenols; Phenotype; Phosphates; Phosphatidylethanolamines; Phosphines; Phospholipids; Phosphorus; Phosphorylation; Photoacoustic Techniques; Photochemotherapy; Photosensitizing Agents; Phylogeny; Phytoestrogens; Pilot Projects; Plant Components, Aerial; Plant Extracts; Plant Immunity; Plant Leaves; Plant Oils; Plants, Medicinal; Plasmodium berghei; Plasmodium falciparum; Platelet Activation; Platelet Function Tests; Pneumonia, Viral; Poaceae; Pogostemon; Poloxamer; Poly I; Poly(ADP-ribose) Polymerase Inhibitors; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Polycyclic Compounds; Polyethylene Glycols; Polylysine; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Population Dynamics; Portasystemic Shunt, Transjugular Intrahepatic; Positron Emission Tomography Computed Tomography; Postoperative Complications; Postprandial Period; Potassium Cyanide; Predictive Value of Tests; Prefrontal Cortex; Pregnancy; Prepulse Inhibition; Prevalence; Procalcitonin; Prodrugs; Prognosis; Progression-Free Survival; Proline; Proof of Concept Study; Prospective Studies; Protein Binding; Protein Conformation; Protein Domains; Protein Folding; Protein Multimerization; Protein Sorting Signals; Protein Structure, Secondary; Proton Pump Inhibitors; Protozoan Proteins; Psychometrics; Pulse Wave Analysis; Pyridines; Pyrrolidines; Quality of Life; Quantum Dots; Quinoxalines; Quorum Sensing; Radiopharmaceuticals; Rain; Random Allocation; Randomized Controlled Trials as Topic; Rats; Rats, Sprague-Dawley; Rats, Wistar; RAW 264.7 Cells; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptor, PAR-1; Receptors, CXCR4; Receptors, Estrogen; Receptors, Glucocorticoid; Receptors, Interleukin-1; Receptors, Interleukin-17; Receptors, Notch; Recombinant Fusion Proteins; Recombinant Proteins; Reducing Agents; Reflex, Startle; Regional Blood Flow; Regression Analysis; Reperfusion Injury; Reproducibility of Results; Republic of Korea; Respiratory Tract Diseases; Retrospective Studies; Reverse Transcriptase Inhibitors; Rhinitis, Allergic; Risk Assessment; Risk Factors; Rituximab; RNA, Messenger; RNA, Ribosomal, 16S; ROC Curve; Rosmarinic Acid; Running; Ruthenium; Rutin; Sarcolemma; Sarcoma; Sarcopenia; Sarcoplasmic Reticulum; SARS-CoV-2; Scavenger Receptors, Class A; Schools; Seasons; Seeds; Sequence Analysis, DNA; Severity of Illness Index; Sex Factors; Shock, Cardiogenic; Short Chain Dehydrogenase-Reductases; Signal Transduction; Silver; Singlet Oxygen; Sinusitis; Skin; Skin Absorption; Small Molecule Libraries; Smoke; Socioeconomic Factors; Soil; Soil Microbiology; Solid Phase Extraction; Solubility; Solvents; Spain; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared; Speech; Speech Perception; Spindle Poles; Spleen; Sporothrix; Staphylococcal Infections; Staphylococcus aureus; Stereoisomerism; Stomach Neoplasms; Stress, Physiological; Stroke Volume; Structure-Activity Relationship; Substrate Specificity; Sulfonamides; Surface Properties; Surface-Active Agents; Surveys and Questionnaires; Survival Rate; T-Lymphocytes, Cytotoxic; Tandem Mass Spectrometry; Temperature; Tenofovir; Terpenes; Tetracycline; Tetrapleura; Textiles; Thermodynamics; Thiobarbituric Acid Reactive Substances; Thrombin; Thyroid Hormones; Thyroid Neoplasms; Tibial Meniscus Injuries; Time Factors; Tissue Distribution; Titanium; Toluidines; Tomography, X-Ray Computed; Tooth; Tramadol; Transcription Factor AP-1; Transcription, Genetic; Transfection; Transgender Persons; Translations; Treatment Outcome; Triglycerides; Ubiquinone; Ubiquitin-Specific Proteases; United Kingdom; United States; Up-Regulation; Vascular Stiffness; Veins; Ventricular Remodeling; Viral Load; Virulence Factors; Virus Replication; Vitis; Voice; Voice Quality; Wastewater; Water; Water Pollutants, Chemical; Water-Electrolyte Balance; Weather; Wildfires; Wnt Signaling Pathway; Wound Healing; X-Ray Diffraction; Xenograft Model Antitumor Assays; Young Adult; Zoogloea | 2022 |
The risk of Plasmodium vivax parasitaemia after P. falciparum malaria: An individual patient data meta-analysis from the WorldWide Antimalarial Resistance Network.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Child, Preschool; Female; Humans; Infant; Malaria; Malaria, Falciparum; Malaria, Vivax; Male; Middle Aged; Parasitemia; Plasmodium vivax; Young Adult | 2020 |
Paediatric formulations of artemisinin-based combination therapies for treating uncomplicated malaria in children.
Topics: Adolescent; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Bias; Child; Child, Preschool; Confidence Intervals; Drug Combinations; Humans; Infant; Malaria, Falciparum; Quinolines; Randomized Controlled Trials as Topic; Suspensions; Tablets; Treatment Failure; Vomiting | 2020 |
Efficacy and safety of dihydroartemisinin-piperaquine versus artemether-lumefantrine for treatment of uncomplicated Plasmodium falciparum malaria in Ugandan children: a systematic review and meta-analysis of randomized control trials.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Child, Preschool; Drug Combinations; Humans; Infant; Malaria, Falciparum; Quinolines; Randomized Controlled Trials as Topic; Uganda | 2021 |
Efficacy of dihydroartemisinin-piperaquine versus artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria among children in Africa: a systematic review and meta-analysis of randomized control trials.
Topics: Adolescent; Africa; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Child, Preschool; Drug Combinations; Humans; Infant; Malaria, Falciparum; Polymerase Chain Reaction; Quality Control; Quinolines; Randomized Controlled Trials as Topic; Regression Analysis; Sensitivity and Specificity; Time Factors | 2021 |
Monitoring antimalarial drug efficacy in the Greater Mekong Subregion: an overview of in vivo results from 2008 to 2010.
Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Asia, Southeastern; Chloroquine; Directly Observed Therapy; Drug Resistance; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Parasitemia; Quinolines | 2013 |
The effect of dosing regimens on the antimalarial efficacy of dihydroartemisinin-piperaquine: a pooled analysis of individual patient data.
Topics: Antimalarials; Artemisinins; Drug Therapy, Combination; Female; Genotype; Humans; Malaria, Falciparum; Male; Quinolines; Risk Factors | 2013 |
Dihydroartemisinin-piperaquine for treating uncomplicated Plasmodium falciparum malaria.
Topics: Adult; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Child; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Malaria, Falciparum; Mefloquine; Parasitemia; Quinolines; Randomized Controlled Trials as Topic | 2014 |
A review of dihydroartemisinin as another gift from traditional Chinese medicine not only for malaria control but also for schistosomiasis control.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Drugs, Chinese Herbal; Female; Malaria, Falciparum; Mice; Praziquantel; Schistosomiasis japonica; Schistosomicides | 2014 |
Clinical determinants of early parasitological response to ACTs in African patients with uncomplicated falciparum malaria: a literature review and meta-analysis of individual patient data.
Topics: Africa; Africa South of the Sahara; Amodiaquine; Antimalarials; Artemisinins; Drug Combinations; Drug Therapy, Combination; Humans; Infant; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Prospective Studies; Quinolines | 2015 |
Prevention and control of malaria in pregnancy - new threats, new opportunities?
Topics: Adult; Animals; Antimalarials; Artemisinins; Culicidae; Drug Combinations; Drug Resistance; Female; Humans; Insecticide-Treated Bednets; Malaria, Falciparum; Malaria, Vivax; Pregnancy; Pregnancy Complications, Parasitic; Primary Prevention; Pyrimethamine; Quinolines; Sulfadoxine | 2017 |
Risk of drug resistance in Plasmodium falciparum malaria therapy-a systematic review and meta-analysis.
Topics: Amodiaquine; Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinolines; Risk; Sulfadoxine | 2017 |
Artemisinin-based combination therapy for treating uncomplicated malaria.
Topics: Antimalarials; Artemisinins; Artesunate; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Parasitemia; Pyrimethamine; Quinolines; Randomized Controlled Trials as Topic; Sulfadoxine | 2009 |
Artemisinin derivatives for treatment of uncomplicated Plasmodium falciparum malaria in Sudan: too early for too much hope.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Combinations; Drug Therapy, Combination; Humans; Malaria, Falciparum; Pyrimethamine; Sudan; Sulfadoxine; Treatment Failure | 2010 |
Antimalarial efficacy of piperaquine-based antimalarial combination therapies: facts and uncertainties.
Topics: Antimalarials; Artemisinins; Drug Combinations; Humans; Malaria, Falciparum; Malaria, Vivax; Quinolines; Treatment Outcome | 2011 |
Dihydroartemisinin/Piperaquine: a review of its use in the treatment of uncomplicated Plasmodium falciparum malaria.
Topics: Antimalarials; Artemisinins; Drug Therapy, Combination; Humans; Malaria, Falciparum; Plasmodium falciparum; Quinolines; Randomized Controlled Trials as Topic; Treatment Outcome | 2012 |
Efficacy and safety of dihydroartemisinin-piperaquine.
Topics: Antimalarials; Artemisinins; Asia, Southeastern; Drug Combinations; Female; Humans; Malaria, Falciparum; Male; Quinolines; Sesquiterpenes; Treatment Outcome | 2007 |
How Chinese scientists discovered qinghaosu (artemisinin) and developed its derivatives? What are the future perspectives?
Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Drug Evaluation; Drug Resistance; Forecasting; Humans; Malaria, Falciparum; Medicine, Chinese Traditional; Sesquiterpenes | 1998 |
The rational use of qinghaosu and its derivatives: what is the future of new compounds?
Topics: Administration, Oral; Administration, Rectal; Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Drug and Narcotic Control; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Registries; Sesquiterpenes; Suppositories; Thailand | 1998 |
172 trial(s) available for artenimol and Plasmodium falciparum Malaria
Article | Year |
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Pharmacokinetics and ex vivo pharmacodynamic antimalarial activity of dihydroartemisinin-piperaquine in patients with uncomplicated falciparum malaria in Vietnam.
Topics: Adolescent; Antimalarials; Artemisinins; Humans; Malaria, Falciparum; Male; Middle Aged; Quinolines; Vietnam; Young Adult | 2009 |
In vitro sensitivities of Plasmodium falciparum to different antimalarial drugs in Uganda.
Topics: Antimalarials; Child; Child, Preschool; Cohort Studies; Drug Resistance; Humans; Malaria, Falciparum; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Treatment Outcome; Uganda | 2010 |
Therapeutic Efficacy of Artemisinin-Based Combination Therapies in Democratic Republic of the Congo and Investigation of Molecular Markers of Antimalarial Resistance.
Topics: Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child, Preschool; Congo; Drug Combinations; Drug Resistance; Female; Humans; Infant; Malaria, Falciparum; Male; Piperazines; Plasmodium falciparum; Quinolines | 2021 |
Adherence to community versus facility-based delivery of monthly malaria chemoprevention with dihydroartemisinin-piperaquine for the post-discharge management of severe anemia in Malawian children: A cluster randomized trial.
Topics: Aftercare; Anemia; Antimalarials; Artemisinins; Child, Preschool; Delivery of Health Care; Drug Combinations; Female; Health Facilities; Humans; Infant; Infant, Newborn; Malaria, Falciparum; Male; Patient Discharge; Plasmodium falciparum; Quinolines; Social Welfare | 2021 |
Identifying an optimal dihydroartemisinin-piperaquine dosing regimen for malaria prevention in young Ugandan children.
Topics: Algorithms; Antimalarials; Artemisinins; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Humans; Incidence; Infant; Malaria, Falciparum; Male; Models, Biological; Outcome Assessment, Health Care; Plasmodium falciparum; Pregnancy; Pregnancy Complications, Parasitic; Quinolines; Uganda | 2021 |
Piperaquine-Induced QTc Prolongation Decreases With Repeated Monthly Dihydroartemisinin-Piperaquine Dosing in Pregnant Ugandan Women.
Topics: Antimalarials; Artemisinins; Drug Combinations; Female; Humans; Long QT Syndrome; Malaria; Malaria, Falciparum; Piperazines; Placenta; Pregnancy; Pregnant Women; Quinolines; Uganda | 2022 |
Single low-dose tafenoquine combined with dihydroartemisinin-piperaquine to reduce Plasmodium falciparum transmission in Ouelessebougou, Mali: a phase 2, single-blind, randomised clinical trial.
Topics: Aminoquinolines; Animals; Artemisinins; Humans; Malaria; Malaria, Falciparum; Mali; Piperazines; Plasmodium falciparum; Quinolines; Single-Blind Method | 2022 |
Monthly sulfadoxine/pyrimethamine-amodiaquine or dihydroartemisinin-piperaquine as malaria chemoprevention in young Kenyan children with sickle cell anemia: A randomized controlled trial.
Topics: Amodiaquine; Anemia, Sickle Cell; Antimalarials; Artemisinins; Chemoprevention; Child; Child, Preschool; Drug Combinations; Female; Humans; Hydroxyurea; Infant; Kenya; Malaria; Malaria, Falciparum; Male; Proguanil; Pyrimethamine; Sulfadoxine | 2022 |
Therapeutic efficacies of artemether-lumefantrine and dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium falciparum and chloroquine and dihydroartemisinin-piperaquine for uncomplicated Plasmodium vivax infection in Ethiopia.
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Chloroquine; Ethiopia; Humans; Malaria, Falciparum; Malaria, Vivax; Plasmodium falciparum; Plasmodium vivax | 2022 |
Safety of age-dosed, single low-dose primaquine in children with glucose-6-phosphate dehydrogenase deficiency who are infected with Plasmodium falciparum in Uganda and the Democratic Republic of the Congo: a randomised, double-blind, placebo-controlled, n
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Child; Democratic Republic of the Congo; Female; Glucosephosphate Dehydrogenase; Glucosephosphate Dehydrogenase Deficiency; Hemoglobins; Humans; Infant; Malaria, Falciparum; Male; Plasmodium falciparum; Primaquine; Uganda; World Health Organization | 2023 |
Effects of anti-malarial prophylaxes on maternal transfer of Immunoglobulin-G (IgG) and association to immunity against Plasmodium falciparum infections among children in a Ugandan birth cohort.
Topics: Antimalarials; Birth Cohort; Child; Drug Combinations; Female; Humans; Immunoglobulin G; Malaria; Malaria, Falciparum; Placenta; Plasmodium falciparum; Pregnancy; Pyrimethamine; Uganda | 2023 |
Therapeutic response to artemisinin combination therapies among individuals with Plasmodium falciparum single infection vs mixed Plasmodium species infections: a retrospective posthoc analysis in Kisumu County, western Kenya.
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Drug Combinations; Humans; Kenya; Malaria; Malaria, Falciparum; Plasmodium falciparum; Quinolines; Reinfection; Retrospective Studies | 2023 |
Protocol for a cluster randomised placebo-controlled trial of adjunctive ivermectin mass drug administration for malaria control on the Bijagós Archipelago of Guinea-Bissau: the MATAMAL trial.
Topics: Animals; Antimalarials; Artemisinins; Guinea-Bissau; Humans; Ivermectin; Malaria; Malaria, Falciparum; Mass Drug Administration; Randomized Controlled Trials as Topic | 2023 |
Effectiveness and safety of intermittent preventive treatment with dihydroartemisinin-piperaquine or artesunate-amodiaquine for reducing malaria and related morbidities in schoolchildren in Tanzania: a randomised controlled trial.
Topics: Amodiaquine; Antimalarials; Artesunate; Child; COVID-19; Drug Combinations; Hemoglobins; Humans; Incidence; Malaria; Malaria, Falciparum; Quinolines; Tanzania | 2023 |
Efficacy and safety of pyronaridine-artesunate (PYRAMAX) for the treatment of
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Clinical Trials, Phase III as Topic; Drug Combinations; Female; Humans; Infant; Malaria; Malaria, Falciparum; Pregnancy; Pregnant Women; Randomized Controlled Trials as Topic; Sub-Saharan African People; Treatment Outcome | 2023 |
Factors affecting haemoglobin dynamics in African children with acute uncomplicated Plasmodium falciparum malaria treated with single low-dose primaquine or placebo.
Topics: alpha-Thalassemia; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Child; Child, Preschool; Female; Glucosephosphate Dehydrogenase Deficiency; Hemoglobins; Humans; Malaria, Falciparum; Male; Plasmodium falciparum; Primaquine | 2023 |
Efficacy and safety of dihydroartemisinin-piperaquine for treatment of Plasmodium falciparum uncomplicated malaria in adult patients on antiretroviral therapy in Malawi and Mozambique: an open label non-randomized interventional trial.
Topics: Adolescent; Adult; Alkynes; Anti-Retroviral Agents; Antimalarials; Artemisinins; Benzoxazines; Cyclopropanes; Drug Combinations; Female; Humans; Malaria, Falciparum; Malawi; Male; Middle Aged; Mozambique; Nevirapine; Plasmodium falciparum; Quinolines; Young Adult | 2019 |
Piperaquine concentration and malaria treatment outcomes in Ugandan children treated for severe malaria with intravenous Artesunate or quinine plus Dihydroartemisinin-Piperaquine.
Topics: Administration, Intravenous; Antimalarials; Artemisinins; Artesunate; Child, Preschool; Female; Follow-Up Studies; Humans; Infant; Malaria, Falciparum; Male; Osmolar Concentration; Plasmodium falciparum; Quinine; Quinolines; Recurrence; Treatment Outcome; Uganda | 2019 |
A Randomized Controlled Trial of Three- versus Five-Day Artemether-Lumefantrine Regimens for Treatment of Uncomplicated Plasmodium falciparum Malaria in Pregnancy in Africa.
Topics: Adult; Africa; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Female; Humans; Malaria, Falciparum; Pregnancy; Young Adult | 2020 |
Mass drug administrations with dihydroartemisinin-piperaquine and single low dose primaquine to eliminate Plasmodium falciparum have only a transient impact on Plasmodium vivax: Findings from randomised controlled trials.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Cambodia; Child; Female; Humans; Malaria, Falciparum; Malaria, Vivax; Male; Mass Drug Administration; Myanmar; Prevalence; Primaquine; Quinolines; Recurrence; Treatment Outcome; Vietnam; Young Adult | 2020 |
Triple artemisinin-based combination therapies versus artemisinin-based combination therapies for uncomplicated Plasmodium falciparum malaria: a multicentre, open-label, randomised clinical trial.
Topics: Adolescent; Adult; Amodiaquine; Anthraquinones; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Plasmodium falciparum; Polymerase Chain Reaction; Quinolines; Treatment Outcome; Young Adult | 2020 |
Impact of Intermittent Mass Testing and Treatment on Incidence of Malaria Infection in a High Transmission Area of Western Kenya.
Topics: Adolescent; Antimalarials; Artemisinins; Child; Child, Preschool; Female; Humans; Incidence; Kenya; Malaria, Falciparum; Male; Mass Screening; Quinolines | 2020 |
Efficacy and safety of artemisinin-based combination therapy and the implications of Pfkelch13 and Pfcoronin molecular markers in treatment failure in Senegal.
Topics: Adolescent; Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Child, Preschool; Drug Combinations; Female; Humans; Infant; Infant, Newborn; Malaria, Falciparum; Male; Microfilament Proteins; Mutation; Plasmodium falciparum; Protozoan Proteins; Quinolines; Senegal; Sequence Analysis, DNA; Treatment Failure | 2020 |
Assessment of the Acceptability of Testing and Treatment during a Mass Drug Administration Trial for Malaria in Zambia Using Mixed Methods.
Topics: Adult; Artemisinins; Attitude to Health; Disease Eradication; Drug Therapy, Combination; Female; Focus Groups; Humans; Malaria, Falciparum; Male; Mass Drug Administration; Medication Adherence; Middle Aged; Patient Acceptance of Health Care; Quinolines; Zambia | 2020 |
A Longitudinal Cohort to Monitor Malaria Infection Incidence during Mass Drug Administration in Southern Province, Zambia.
Topics: Adolescent; Antimalarials; Artemisinins; Child; Child, Preschool; Disease Eradication; Drug Therapy, Combination; Family Characteristics; Female; Humans; Incidence; Longitudinal Studies; Malaria, Falciparum; Male; Mass Drug Administration; Quinolines; Young Adult; Zambia | 2020 |
Implications of the MDA Trial in Southern Province, Zambia, for Malaria Control and Elimination.
Topics: Antimalarials; Artemisinins; Disease Eradication; Drug Therapy, Combination; Humans; Malaria, Falciparum; Mass Drug Administration; Plasmodium falciparum; Prevalence; Program Evaluation; Quinolines; Zambia | 2020 |
Cost-Effectiveness of Focal Mass Drug Administration and Mass Drug Administration with Dihydroartemisinin-Piperaquine for Malaria Prevention in Southern Province, Zambia: Results of a Community-Randomized Controlled Trial.
Topics: Antimalarials; Artemisinins; Cost-Benefit Analysis; Disease Eradication; Drug Costs; Drug Therapy, Combination; Health Care Costs; Humans; Malaria, Falciparum; Mass Drug Administration; Plasmodium falciparum; Quality-Adjusted Life Years; Quinolines; Zambia | 2020 |
Impact of Four Rounds of Mass Drug Administration with Dihydroartemisinin-Piperaquine Implemented in Southern Province, Zambia.
Topics: Antimalarials; Artemisinins; Disease Eradication; Drug Therapy, Combination; Humans; Incidence; Malaria, Falciparum; Mass Drug Administration; Program Evaluation; Quinolines; Zambia | 2020 |
Treatment Coverage Estimation for Mass Drug Administration for Malaria with Dihydroartemisinin-Piperaquine in Southern Province, Zambia.
Topics: Antimalarials; Artemisinins; Drug Therapy, Combination; Family Characteristics; Humans; Malaria, Falciparum; Mass Drug Administration; Program Evaluation; Quinolines; Zambia | 2020 |
Moving from Malaria Burden Reduction toward Elimination: An Evaluation of Mass Drug Administration in Southern Province, Zambia.
Topics: Antimalarials; Artemisinins; Disease Eradication; Drug Therapy, Combination; Humans; Malaria, Falciparum; Mass Drug Administration; Program Evaluation; Quinolines; Zambia | 2020 |
Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain; Acyclic Monoterpenes; Adenine Nucleotides; Adhesins, Escherichia coli; Adipocytes; Adipocytes, Brown; Adipogenesis; Administration, Inhalation; Administration, Oral; Adrenal Cortex Hormones; Adsorption; Adult; Aeromonas hydrophila; Africa; Aged; Aged, 80 and over; Agrobacterium tumefaciens; Air; Air Pollutants; Air Pollution; Air Pollution, Indoor; Algorithms; Alkaloids; Alkynes; Allosteric Regulation; Amines; Amino Acid Sequence; Amino Acids; Amino Acids, Branched-Chain; Aminoisobutyric Acids; Aminopyridines; Amyotrophic Lateral Sclerosis; Anaerobic Threshold; Angiography; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animal Distribution; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Ankle Joint; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Inflammatory Agents; Antibodies, Bacterial; Antifungal Agents; Antimalarials; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antioxidants; Antiretroviral Therapy, Highly Active; Antiviral Agents; Aotidae; Apelin; Apoptosis; Arabidopsis Proteins; Argentina; Arginine; Artemisinins; Arthritis, Experimental; Arthritis, Rheumatoid; Arthroscopy; Aspergillus; Aspergillus niger; Asteraceae; Asthma; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; Auditory Cortex; Autoantibodies; Autophagy; Bacteria; Bacterial Infections; Bacterial Proteins; Bacterial Typing Techniques; Base Composition; Base Sequence; Basketball; Beclin-1; Benzhydryl Compounds; Benzimidazoles; Benzo(a)pyrene; Benzofurans; Benzoxazines; Bereavement; beta Catenin; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Betacoronavirus; Betaine; Binding Sites; Biofilms; Biological Assay; Biological Availability; Biological Evolution; Biomarkers; Biomechanical Phenomena; Biopolymers; Biopsy; Bismuth; Blood Glucose; Blood Platelets; Blood Pressure; Body Composition; Body Weight; Bone Marrow; Bone Marrow Cells; Bone Regeneration; Boron; Botrytis; Brain Ischemia; Brain Neoplasms; Brain-Derived Neurotrophic Factor; Brazil; Breast Neoplasms; Breath Tests; Bronchoalveolar Lavage Fluid; Burkholderia; C-Reactive Protein; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Calcification, Physiologic; Calcium; Calcium Signaling; Calorimetry, Differential Scanning; Cameroon; Camptothecin; Candida; Candida albicans; Capillaries; Carbapenem-Resistant Enterobacteriaceae; Carbapenems; Carbohydrate Conformation; Carbon; Carbon Dioxide; Carbon Isotopes; Carcinoma, Ovarian Epithelial; Cardiac Output; Cardiomyopathy, Hypertrophic; Cardiotonic Agents; Cardiovascular Diseases; Caregivers; Carps; Case-Control Studies; Catalase; Catalysis; Cats; CD4 Lymphocyte Count; Cell Culture Techniques; Cell Differentiation; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Proliferation; Cell Survival; Cells, Cultured; Cellulose; Centrosome; Ceratopogonidae; Chickens; Child; China; Cholera Toxin; Choline; Cholinesterases; Chromatography, High Pressure Liquid; Chromatography, Liquid; Chromatography, Micellar Electrokinetic Capillary; Chromatography, Reverse-Phase; Chronic Disease; Cinnamates; Cities; Citrates; Climate Change; Clinical Trials, Phase III as Topic; Coal; Coal Mining; Cohort Studies; Coinfection; Colchicine; Colony Count, Microbial; Colorectal Neoplasms; Coloring Agents; Common Cold; Complement Factor H; Computational Biology; Computer Simulation; Continuous Positive Airway Pressure; Contrast Media; Coordination Complexes; Coronary Artery Bypass; Coronavirus 3C Proteases; Coronavirus Infections; Coronavirus Protease Inhibitors; Corynebacterium glutamicum; Cosmetics; COVID-19; Creatinine; Cross-Sectional Studies; Crotonates; Crystallography, X-Ray; Cues; Culicidae; Culture Media; Curcuma; Cyclopentanes; Cyclopropanes; Cymbopogon; Cystine; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C19 Inhibitors; Cytokines; Databases, Genetic; Death; Dendritic Cells; Density Functional Theory; Depsides; Diabetes Mellitus, Type 2; Diamond; Diarylheptanoids; Dibenzofurans; Dibenzofurans, Polychlorinated; Diclofenac; Diet; Dietary Carbohydrates; Dietary Supplements; Diffusion Magnetic Resonance Imaging; Dioxins; Diphenylamine; Disease Outbreaks; Disease Susceptibility; Disulfides; Dithiothreitol; Dizocilpine Maleate; DNA Methylation; DNA-Binding Proteins; DNA, Bacterial; Dogs; Dose-Response Relationship, Drug; Double-Blind Method; Doublecortin Protein; Drosophila melanogaster; Droughts; Drug Carriers; Drug Combinations; Drug Delivery Systems; Drug Liberation; Drug Resistance; Drug Resistance, Bacterial; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Dust; Dynactin Complex; Dysferlin; Echo-Planar Imaging; Echocardiography; Edaravone; Egypt; Elasticity; Electrodes; Electrolytes; Emodin; Emtricitabine; Endometriosis; Endothelium, Vascular; Endotoxins; Energy Metabolism; Energy Transfer; Enterobacteriaceae; Enterococcus faecalis; Enterotoxigenic Escherichia coli; Environmental Monitoring; Enzyme Inhibitors; Epidemiologic Factors; Epigenesis, Genetic; Erythrocytes; Escherichia coli; Escherichia coli Infections; Escherichia coli Vaccines; Esophageal Neoplasms; Esophagectomy; Esophagogastric Junction; Esterases; Esterification; Ethanol; Ethiopia; Ethnicity; Eucalyptus; Evidence-Based Practice; Exercise; Exercise Tolerance; Extracorporeal Membrane Oxygenation; Family; Fatty Acids; Feedback; Female; Ferric Compounds; Fibrin Fibrinogen Degradation Products; Filtration; Fish Diseases; Flavonoids; Flavonols; Fluorodeoxyglucose F18; Follow-Up Studies; Food Microbiology; Food Preservation; Forests; Fossils; Free Radical Scavengers; Freund's Adjuvant; Fruit; Fungi; Gallium; Gender Identity; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Plant; Gene Knockdown Techniques; Genes, Bacterial; Genes, Plant; Genetic Predisposition to Disease; Genitalia; Genotype; Glomerulonephritis, IGA; Glottis; Glucocorticoids; Glucose; Glucuronides; Glutathione Transferase; Glycogen Synthase Kinase 3 beta; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Grassland; Guinea Pigs; Half-Life; Head Kidney; Heart Atria; Heart Rate; Heart Septum; HEK293 Cells; Hematopoietic Stem Cells; Hemodynamics; Hep G2 Cells; Hepacivirus; Hepatitis C; Hepatitis C, Chronic; Hepatocytes; Hesperidin; High-Frequency Ventilation; High-Temperature Requirement A Serine Peptidase 1; Hippocampus; Hirudins; History, 20th Century; History, 21st Century; HIV Infections; Homeostasis; Hominidae; Housing, Animal; Humans; Hydrocarbons, Brominated; Hydrogen Bonding; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxybutyrates; Hydroxyl Radical; Hypertension; Hypothyroidism; Image Interpretation, Computer-Assisted; Immunoconjugates; Immunogenic Cell Death; Indoles; Infant, Newborn; Infant, Premature; Infarction, Middle Cerebral Artery; Inflammation; Inflammation Mediators; Infrared Rays; Inhibitory Concentration 50; Injections, Intravenous; Interferon-gamma; Interleukin-23; Interleukin-4; Interleukin-6; Intermediate Filaments; Intermittent Claudication; Intestine, Small; Iridoid Glucosides; Iridoids; Iron; Isomerism; Isotope Labeling; Isoxazoles; Itraconazole; Kelch-Like ECH-Associated Protein 1; Ketoprofen; Kidney Failure, Chronic; Kinetics; Klebsiella pneumoniae; Lactams, Macrocyclic; Lactobacillus; Lactulose; Lakes; Lamivudine; Laparoscopy; Laparotomy; Laryngoscopy; Leucine; Limit of Detection; Linear Models; Lipid A; Lipopolysaccharides; Listeria monocytogenes; Liver; Liver Cirrhosis; Logistic Models; Longitudinal Studies; Losartan; Low Back Pain; Lung; Lupinus; Lupus Erythematosus, Systemic; Machine Learning; Macular Degeneration; Madin Darby Canine Kidney Cells; Magnetic Phenomena; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Magnetics; Malaria, Falciparum; Male; Mannans; MAP Kinase Signaling System; Mass Spectrometry; Melatonin; Membrane Glycoproteins; Membrane Proteins; Meniscectomy; Menisci, Tibial; Mephenytoin; Mesenchymal Stem Cells; Metal Nanoparticles; Metal-Organic Frameworks; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; Mice, Obese; Mice, Transgenic; Microbial Sensitivity Tests; Microcirculation; MicroRNAs; Microscopy, Video; Microtubules; Microvascular Density; Microwaves; Middle Aged; Minimally Invasive Surgical Procedures; Models, Animal; Models, Biological; Models, Molecular; Models, Theoretical; Molecular Docking Simulation; Molecular Structure; Molecular Weight; Morus; Mouth Floor; Multicenter Studies as Topic; Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting; Muscle, Skeletal; Myocardial Ischemia; Myocardium; NAD; NADP; Nanocomposites; Nanoparticles; Naphthols; Nasal Lavage Fluid; Nasal Mucosa; Neisseria meningitidis; Neoadjuvant Therapy; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Neoplasms, Experimental; Neural Stem Cells; Neuroblastoma; Neurofilament Proteins; Neurogenesis; Neurons; New York; NF-E2-Related Factor 2; NF-kappa B; Nicotine; Nitriles; Nitrogen; Nitrogen Fixation; North America; Observer Variation; Occupational Exposure; Ochrobactrum; Oils, Volatile; Olea; Oligosaccharides; Omeprazole; Open Field Test; Optimism; Oregon; Oryzias; Osmolar Concentration; Osteoarthritis; Osteoblasts; Osteogenesis; Ovarian Neoplasms; Ovariectomy; Oxadiazoles; Oxidation-Reduction; Oxidative Stress; Oxygen; Ozone; p38 Mitogen-Activated Protein Kinases; Pakistan; Pandemics; Particle Size; Particulate Matter; Patient-Centered Care; Pelargonium; Peptides; Perception; Peripheral Arterial Disease; Peroxides; Pets; Pharmaceutical Preparations; Pharmacogenetics; Phenobarbital; Phenols; Phenotype; Phosphates; Phosphatidylethanolamines; Phosphines; Phospholipids; Phosphorus; Phosphorylation; Photoacoustic Techniques; Photochemotherapy; Photosensitizing Agents; Phylogeny; Phytoestrogens; Pilot Projects; Plant Components, Aerial; Plant Extracts; Plant Immunity; Plant Leaves; Plant Oils; Plants, Medicinal; Plasmodium berghei; Plasmodium falciparum; Platelet Activation; Platelet Function Tests; Pneumonia, Viral; Poaceae; Pogostemon; Poloxamer; Poly I; Poly(ADP-ribose) Polymerase Inhibitors; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Polycyclic Compounds; Polyethylene Glycols; Polylysine; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Population Dynamics; Portasystemic Shunt, Transjugular Intrahepatic; Positron Emission Tomography Computed Tomography; Postoperative Complications; Postprandial Period; Potassium Cyanide; Predictive Value of Tests; Prefrontal Cortex; Pregnancy; Prepulse Inhibition; Prevalence; Procalcitonin; Prodrugs; Prognosis; Progression-Free Survival; Proline; Proof of Concept Study; Prospective Studies; Protein Binding; Protein Conformation; Protein Domains; Protein Folding; Protein Multimerization; Protein Sorting Signals; Protein Structure, Secondary; Proton Pump Inhibitors; Protozoan Proteins; Psychometrics; Pulse Wave Analysis; Pyridines; Pyrrolidines; Quality of Life; Quantum Dots; Quinoxalines; Quorum Sensing; Radiopharmaceuticals; Rain; Random Allocation; Randomized Controlled Trials as Topic; Rats; Rats, Sprague-Dawley; Rats, Wistar; RAW 264.7 Cells; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptor, PAR-1; Receptors, CXCR4; Receptors, Estrogen; Receptors, Glucocorticoid; Receptors, Interleukin-1; Receptors, Interleukin-17; Receptors, Notch; Recombinant Fusion Proteins; Recombinant Proteins; Reducing Agents; Reflex, Startle; Regional Blood Flow; Regression Analysis; Reperfusion Injury; Reproducibility of Results; Republic of Korea; Respiratory Tract Diseases; Retrospective Studies; Reverse Transcriptase Inhibitors; Rhinitis, Allergic; Risk Assessment; Risk Factors; Rituximab; RNA, Messenger; RNA, Ribosomal, 16S; ROC Curve; Rosmarinic Acid; Running; Ruthenium; Rutin; Sarcolemma; Sarcoma; Sarcopenia; Sarcoplasmic Reticulum; SARS-CoV-2; Scavenger Receptors, Class A; Schools; Seasons; Seeds; Sequence Analysis, DNA; Severity of Illness Index; Sex Factors; Shock, Cardiogenic; Short Chain Dehydrogenase-Reductases; Signal Transduction; Silver; Singlet Oxygen; Sinusitis; Skin; Skin Absorption; Small Molecule Libraries; Smoke; Socioeconomic Factors; Soil; Soil Microbiology; Solid Phase Extraction; Solubility; Solvents; Spain; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared; Speech; Speech Perception; Spindle Poles; Spleen; Sporothrix; Staphylococcal Infections; Staphylococcus aureus; Stereoisomerism; Stomach Neoplasms; Stress, Physiological; Stroke Volume; Structure-Activity Relationship; Substrate Specificity; Sulfonamides; Surface Properties; Surface-Active Agents; Surveys and Questionnaires; Survival Rate; T-Lymphocytes, Cytotoxic; Tandem Mass Spectrometry; Temperature; Tenofovir; Terpenes; Tetracycline; Tetrapleura; Textiles; Thermodynamics; Thiobarbituric Acid Reactive Substances; Thrombin; Thyroid Hormones; Thyroid Neoplasms; Tibial Meniscus Injuries; Time Factors; Tissue Distribution; Titanium; Toluidines; Tomography, X-Ray Computed; Tooth; Tramadol; Transcription Factor AP-1; Transcription, Genetic; Transfection; Transgender Persons; Translations; Treatment Outcome; Triglycerides; Ubiquinone; Ubiquitin-Specific Proteases; United Kingdom; United States; Up-Regulation; Vascular Stiffness; Veins; Ventricular Remodeling; Viral Load; Virulence Factors; Virus Replication; Vitis; Voice; Voice Quality; Wastewater; Water; Water Pollutants, Chemical; Water-Electrolyte Balance; Weather; Wildfires; Wnt Signaling Pathway; Wound Healing; X-Ray Diffraction; Xenograft Model Antitumor Assays; Young Adult; Zoogloea | 2022 |
Infant sex modifies associations between placental malaria and risk of malaria in infancy.
Topics: Adult; Antimalarials; Artemisinins; Drug Combinations; Female; Humans; Incidence; Infant; Infant, Newborn; Malaria, Falciparum; Male; Placenta Diseases; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Quinolines; Sulfadoxine; Young Adult | 2020 |
Reactive, self-administered malaria treatment against asymptomatic malaria infection: results of a cluster randomized controlled trial in The Gambia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Asymptomatic Infections; Child; Child, Preschool; Cluster Analysis; Drug Combinations; Female; Gambia; Humans; Incidence; Infant; Malaria, Falciparum; Male; Middle Aged; Prevalence; Quinolines; Self Administration; Young Adult | 2021 |
A randomized controlled trial of dihydroartemisinin-piperaquine, artesunate-mefloquine and extended artemether-lumefantrine treatments for malaria in pregnancy on the Thailand-Myanmar border.
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Drug Therapy, Combination; Female; Humans; Infant, Newborn; Malaria; Malaria, Falciparum; Mefloquine; Myanmar; Pregnancy; Premature Birth; Quinolines; Thailand | 2021 |
Mass drug administration for the acceleration of malaria elimination in a region of Myanmar with artemisinin-resistant falciparum malaria: a cluster-randomised trial.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Cluster Analysis; Disease Eradication; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Mass Drug Administration; Myanmar; Primaquine; Quinolines; Young Adult | 2021 |
Imatinib augments standard malaria combination therapy without added toxicity.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Drug Therapy, Combination; Fever; Humans; Imatinib Mesylate; Malaria, Falciparum; Middle Aged; Quinolines; Treatment Outcome; Vietnam; Young Adult | 2021 |
Efficacies of DHA-PPQ and AS/SP in patients with uncomplicated Plasmodium falciparum malaria in an area of an unstable seasonal transmission in Sudan.
Topics: Adolescent; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Parasitemia; Plasmodium falciparum; Pyrimethamine; Quinolines; Sudan; Sulfadoxine; Time Factors; Treatment Outcome; Young Adult | 2017 |
Changing Antimalarial Drug Sensitivities in Uganda.
Topics: Adolescent; Amodiaquine; Antimalarials; Artemisinins; Aspartic Acid Endopeptidases; Child; Child, Preschool; Chloroquine; Drug Resistance; Ethanolamines; Female; Fluorenes; Gene Expression; Humans; Infant; Inhibitory Concentration 50; Lumefantrine; Malaria, Falciparum; Male; Mefloquine; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Mutation; Parasitic Sensitivity Tests; Plasmodium falciparum; Protozoan Proteins; Quinolines; Uganda; Young Adult | 2017 |
Efficacy and Tolerability Outcomes of a Phase II, Randomized, Open-Label, Multicenter Study of a New Water-Dispersible Pediatric Formulation of Dihydroartemisinin-Piperaquine for the Treatment of Uncomplicated Plasmodium falciparum Malaria in African Infa
Topics: Africa; Antimalarials; Artemisinins; Drug Combinations; Female; Humans; Infant; Kaplan-Meier Estimate; Malaria, Falciparum; Male; Quinolines; Treatment Outcome | 2018 |
Community-led Responses for Elimination (CoRE): a study protocol for a community randomized controlled trial assessing the effectiveness of community-level, reactive focal drug administration for reducing Plasmodium falciparum infection prevalence and inc
Topics: Adolescent; Adult; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Child, Preschool; Clinical Protocols; Community Health Services; Drug Administration Schedule; Drug Combinations; Ethanolamines; Female; Fluorenes; Humans; Incidence; Infant; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Prevalence; Quinolines; Research Design; Risk Factors; Time Factors; Treatment Outcome; Young Adult; Zambia | 2017 |
Efficacy and safety of primaquine and methylene blue for prevention of Plasmodium falciparum transmission in Mali: a phase 2, single-blind, randomised controlled trial.
Topics: Adolescent; Adult; Amodiaquine; Artemisinins; Child; Child, Preschool; Drug Combinations; Humans; Malaria, Falciparum; Mali; Methylene Blue; Middle Aged; Plasmodium falciparum; Primaquine; Pyrimethamine; Quinolines; Sulfadoxine; Young Adult | 2018 |
A Controlled Trial of Mass Drug Administration to Interrupt Transmission of Multidrug-Resistant Falciparum Malaria in Cambodian Villages.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Cambodia; Child; Child, Preschool; Cross-Sectional Studies; Drug Resistance, Multiple; Female; Humans; Incidence; Malaria, Falciparum; Male; Mass Drug Administration; Middle Aged; Plasmodium falciparum; Plasmodium vivax; Prevalence; Quinolines; Young Adult | 2018 |
Intermittent Preventive Treatment for Malaria in Pregnancy: Optimization of Target Concentrations of Dihydroartemisinin-Piperaquine.
Topics: Artemisinins; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Humans; Infant, Newborn; Malaria, Falciparum; Models, Biological; Pregnancy; Pregnancy Complications, Parasitic; Pregnancy Outcome; Quinolines | 2018 |
Comparison of Two Genotyping Methods for Distinguishing Recrudescence from Reinfection in Antimalarial Drug Efficacy/Effectiveness Trials.
Topics: Antigens, Protozoan; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Cluster Analysis; Drug Combinations; Female; Gene Expression; Genotype; Genotyping Techniques; Humans; Malaria, Falciparum; Malawi; Male; Merozoite Surface Protein 1; Merozoites; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Quinolines; Recurrence; Treatment Outcome | 2018 |
High efficacy of artemether-lumefantrine and dihydroartemisinin-piperaquine for the treatment of uncomplicated falciparum malaria in Muheza and Kigoma Districts, Tanzania.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Child, Preschool; Female; Humans; Infant; Malaria, Falciparum; Male; Quinolines; Tanzania | 2018 |
Dihydroartemisinin-piperaquine for intermittent preventive treatment of malaria during pregnancy and risk of malaria in early childhood: A randomized controlled trial.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child, Preschool; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Humans; Incidence; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Malaria, Falciparum; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Quinolines; Sulfadoxine; Time Factors; Treatment Outcome; Uganda; Young Adult | 2018 |
A randomized trial of dihydroartemisinin-piperaquine versus artemether-lumefantrine for treatment of uncomplicated Plasmodium falciparum malaria in Mali.
Topics: Adolescent; Adult; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Child, Preschool; Drug Combinations; Ethanolamines; Female; Fluorenes; Humans; Infant; Malaria, Falciparum; Male; Mali; Middle Aged; Plasmodium falciparum; Quinolines; Young Adult | 2018 |
Efficacy of artemether-lumefantrine and dihydroartemisinin-piperaquine for the treatment of uncomplicated malaria in Papua New Guinea.
Topics: Adolescent; Adult; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Child, Preschool; Drug Combinations; Ethanolamines; Female; Fluorenes; Humans; Infant; Inhibitory Concentration 50; Malaria, Falciparum; Malaria, Vivax; Male; Middle Aged; Papua New Guinea; Plasmodium falciparum; Plasmodium vivax; Quinolines; Young Adult | 2018 |
Cluster-randomized trial of monthly malaria prophylaxis versus focused screening and treatment: a study protocol to define malaria elimination strategies in Cambodia.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Cambodia; Child; Child, Preschool; Disease Eradication; Drug Administration Schedule; Drug Combinations; Female; Humans; Insecticides; Malaria, Falciparum; Male; Mass Screening; Middle Aged; Military Medicine; Military Personnel; Mosquito Control; Pilot Projects; Plasmodium falciparum; Predictive Value of Tests; Primaquine; Protective Clothing; Quinolines; Randomized Controlled Trials as Topic; Time Factors; Treatment Outcome; Young Adult | 2018 |
The dynamic of asymptomatic Plasmodium falciparum infections following mass drug administrations with dihydroarteminisin-piperaquine plus a single low dose of primaquine in Savannakhet Province, Laos.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Asymptomatic Infections; Child; Drug Combinations; Female; Humans; Incidence; Laos; Malaria, Falciparum; Male; Mass Drug Administration; Middle Aged; Plasmodium falciparum; Prevalence; Quinolines; Young Adult | 2018 |
Comparative Efficacy of Artemether-Lumefantrine and Dihydroartemisinin-Piperaquine for the Treatment of Uncomplicated Malaria in Ugandan Children.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child, Preschool; Comparative Effectiveness Research; Drug Combinations; Drug Resistance; Female; Genotype; Humans; Infant; Malaria, Falciparum; Male; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Parasitemia; Plasmodium falciparum; Protozoan Proteins; Quinolines; Recurrence; Single-Blind Method; Uganda | 2019 |
Optimal dosing of dihydroartemisinin-piperaquine for seasonal malaria chemoprevention in young children.
Topics: Antimalarials; Artemisinins; Chemoprevention; Child, Preschool; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Quinolines; Seasons | 2019 |
The tolerability of single low dose primaquine in glucose-6-phosphate deficient and normal falciparum-infected Cambodians.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Cambodia; Child; Child, Preschool; Female; Glucose-6-Phosphate; Glucosephosphate Dehydrogenase Deficiency; Humans; Malaria, Falciparum; Male; Middle Aged; Parasitemia; Plasmodium falciparum; Primaquine; Young Adult | 2019 |
Monthly sulfadoxine-pyrimethamine versus dihydroartemisinin-piperaquine for intermittent preventive treatment of malaria in pregnancy: a double-blind, randomised, controlled, superiority trial.
Topics: Adult; Antimalarials; Artemisinins; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Pregnancy; Pregnancy Complications, Parasitic; Pregnancy Outcome; Pyrimethamine; Quinolines; Sulfadoxine; Uganda; Young Adult | 2019 |
Intermittent screening and treatment with dihydroartemisinin-piperaquine and intermittent preventive therapy with sulfadoxine-pyrimethamine have similar effects on malaria antibody in pregnant Malawian women.
Topics: Adolescent; Adult; Antibodies, Protozoan; Antimalarials; Artemisinins; Drug Combinations; Female; Humans; Malaria, Falciparum; Malawi; Mass Screening; Plasmodium falciparum; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Quinolines; Sulfadoxine; Young Adult | 2019 |
High therapeutic efficacy of artemether-lumefantrine and dihydroartemisinin-piperaquine for the treatment of uncomplicated falciparum malaria in Somalia.
Topics: Adolescent; Adult; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Child, Preschool; Female; Humans; Infant; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Quinolines; Somalia; Young Adult | 2019 |
Intermittent preventive treatment with dihydroartemisinin-piperaquine and risk of malaria following cessation in young Ugandan children: a double-blind, randomised, controlled trial.
Topics: Anemia; Antimalarials; Artemisinins; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Incidence; Infant; Malaria, Falciparum; Male; Parasitemia; Quinolines; Risk Assessment; Uganda; Withholding Treatment | 2019 |
Determinants of dihydroartemisinin-piperaquine treatment failure in Plasmodium falciparum malaria in Cambodia, Thailand, and Vietnam: a prospective clinical, pharmacological, and genetic study.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Cambodia; Drug Resistance, Multiple; Drug Therapy, Combination; Female; High-Throughput Nucleotide Sequencing; Humans; Malaria, Falciparum; Male; Mefloquine; Membrane Transport Proteins; Middle Aged; Mutation; Plasmodium falciparum; Prospective Studies; Protozoan Proteins; Quinolines; Thailand; Treatment Failure; Vietnam; Young Adult | 2019 |
Efficacy and safety of intermittent preventive treatment and intermittent screening and treatment versus single screening and treatment with dihydroartemisinin-piperaquine for the control of malaria in pregnancy in Indonesia: a cluster-randomised, open-la
Topics: Adult; Antimalarials; Artemisinins; Drug Combinations; Female; Humans; Indonesia; Malaria, Falciparum; Malaria, Vivax; Parturition; Postpartum Period; Pregnancy; Pregnancy Complications, Parasitic; Prevalence; Quinolines; Young Adult | 2019 |
Malaria transmission after artemether-lumefantrine and dihydroartemisinin-piperaquine: a randomized trial.
Topics: Animals; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Child, Preschool; Culicidae; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Infant; Kenya; Malaria, Falciparum; Male; Plasmodium falciparum; Polymerase Chain Reaction; Quinolines; Secondary Prevention; Time Factors; Treatment Outcome | 2013 |
A randomized trial of artemether-lumefantrine and dihydroartemisinin-piperaquine in the treatment of uncomplicated malaria among children in western Kenya.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child, Preschool; Drug Combinations; Ethanolamines; Female; Fluorenes; Humans; Infant; Kenya; Malaria, Falciparum; Male; Quinolines; Treatment Outcome | 2013 |
Residual Plasmodium falciparum parasitemia in Kenyan children after artemisinin-combination therapy is associated with increased transmission to mosquitoes and parasite recurrence.
Topics: Animals; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Chi-Square Distribution; Child; Child, Preschool; DNA, Protozoan; Drug Combinations; Drug Resistance; Ethanolamines; Fluorenes; Humans; Infant; Kenya; Malaria, Falciparum; Parasitemia; Plasmodium falciparum; Polymerase Chain Reaction; Quinolines; Recurrence | 2013 |
Monitoring the efficacy and safety of three artemisinin based-combinations therapies in Senegal: results from two years surveillance.
Topics: Adolescent; Adult; Amodiaquine; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Combinations; Female; Humans; Malaria, Falciparum; Male; Plasmodium falciparum; Population Surveillance; Quinolines; Senegal; Young Adult | 2013 |
Early parasite clearance following artemisinin-based combination therapy among Ugandan children with uncomplicated Plasmodium falciparum malaria.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child, Preschool; Drug Combinations; Drug Resistance; Ethanolamines; Fluorenes; Humans; Kinetics; Longitudinal Studies; Malaria, Falciparum; Parasitemia; Plasmodium falciparum; Quinolines; Risk Factors; Uganda | 2014 |
Efficacy and safety of artemether-lumefantrine and dihydroartemisinin-piperaquine in the treatment of uncomplicated Plasmodium falciparum malaria in Kenyan children aged less than five years: results of an open-label, randomized, single-centre study.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child, Preschool; Drug Combinations; Ethanolamines; Fluorenes; Humans; Infant; Kenya; Malaria, Falciparum; Plasmodium falciparum; Polymerase Chain Reaction; Quinolines; Tablets | 2014 |
Pharmacokinetics of artesunate alone and in combination with sulfadoxine/pyrimethamine in healthy Sudanese volunteers.
Topics: Administration, Oral; Adult; Antimalarials; Artemisinins; Artesunate; Cross-Over Studies; Drug Combinations; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Plasmodium falciparum; Pyrimethamine; Sudan; Sulfadoxine; Volunteers; Young Adult | 2014 |
Impact of intermittent preventive treatment with dihydroartemisinin-piperaquine on malaria in Ugandan schoolchildren: a randomized, placebo-controlled trial.
Topics: Anemia; Antimalarials; Artemisinins; Child; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Humans; Malaria; Malaria, Falciparum; Male; Parasitemia; Prevalence; Quinolines; Risk Factors; Uganda | 2014 |
Efficacy of two versus three-day regimens of dihydroartemisinin-piperaquine for uncomplicated malaria in military personnel in northern Cambodia: an open-label randomized trial.
Topics: Adult; Antimalarials; Artemisinins; Cambodia; Drug Administration Schedule; Drug Resistance, Multiple; Humans; Malaria, Falciparum; Malaria, Vivax; Male; Military Personnel; Models, Biological; Quinolines; Recurrence | 2014 |
Longitudinal outcomes in a cohort of Ugandan children randomized to artemether-lumefantrine versus dihydroartemisinin-piperaquine for the treatment of malaria.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child, Preschool; Cohort Studies; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; HIV Infections; Hospitalization; Humans; Infant; Longitudinal Studies; Malaria, Falciparum; Male; Quinolines; Recurrence; Time Factors; Treatment Outcome; Uganda | 2014 |
[Therapeutic efficacy and safety of compound dihydroartemisinin/piperaquine for uncomplicated Plasmodium falciparum infection in Laiza City of Myanmar bordering on China].
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Child, Preschool; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Quinolines; Treatment Outcome; Young Adult | 2011 |
Randomized comparison of the efficacies and tolerabilities of three artemisinin-based combination treatments for children with acute Plasmodium falciparum malaria in the Democratic Republic of the Congo.
Topics: Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child, Preschool; Democratic Republic of the Congo; Drug Combinations; Erythrocyte Count; Ethanolamines; Female; Fluorenes; Humans; Malaria, Falciparum; Male; Parasitemia; Plasmodium falciparum; Quinolines; Treatment Outcome | 2014 |
Pharmacokinetic evaluation of intravenous artesunate in adults with uncomplicated falciparum malaria in Kenya: a phase II study.
Topics: Activation, Metabolic; Adult; Aged; Antimalarials; Artemisinins; Artesunate; Atovaquone; Chromatography, Liquid; Drug Combinations; Drug Compounding; Drug Monitoring; Female; Half-Life; Humans; Infusions, Intravenous; Kenya; Malaria, Falciparum; Male; Mass Spectrometry; Middle Aged; Proguanil; Reticulocytes; Young Adult | 2014 |
Dihydroartemisinin-piperaquine failure in Cambodia.
Topics: Adult; Antimalarials; Artemisinins; Cambodia; Drug Combinations; Humans; Malaria, Falciparum; Quinolines; Recurrence; Treatment Failure | 2014 |
Delayed parasite clearance after treatment with dihydroartemisinin-piperaquine in Plasmodium falciparum malaria patients in central Vietnam.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Resistance; Drug Therapy, Combination; Erythrocytes; Female; Genotyping Techniques; Humans; Infant; Inhibitory Concentration 50; Malaria, Falciparum; Male; Microfilament Proteins; Middle Aged; Molecular Typing; Mutation; Parasitic Sensitivity Tests; Plasmodium falciparum; Protozoan Proteins; Quinolines; Time Factors; Vietnam | 2014 |
Pharmacokinetic interactions between primaquine and pyronaridine-artesunate in healthy adult Thai subjects.
Topics: Administration, Oral; Adult; Antimalarials; Artemisinins; Artesunate; Cross-Over Studies; Drug Interactions; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Malaria, Vivax; Male; Middle Aged; Naphthyridines; Primaquine; Thailand; Young Adult | 2015 |
Randomized non-inferiority and safety trial of dihydroartemisin-piperaquine and artesunate-amodiaquine versus artemether-lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria in Cameroonian children.
Topics: Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Cameroon; Child; Child, Preschool; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Ethanolamines; Fluorenes; Humans; Infant; Malaria, Falciparum; Male; Quinolines; Treatment Outcome | 2015 |
Increased systemic exposures of artemether and dihydroartemisinin in infants under 5 kg with uncomplicated Plasmodium falciparum malaria treated with artemether-lumefantrine (Coartem®).
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Ethanolamines; Female; Fluorenes; Humans; Infant; Malaria, Falciparum; Male; Treatment Outcome | 2015 |
Evidence of Plasmodium falciparum Malaria Multidrug Resistance to Artemisinin and Piperaquine in Western Cambodia: Dihydroartemisinin-Piperaquine Open-Label Multicenter Clinical Assessment.
Topics: Adolescent; Adult; Antigens, Bacterial; Antigens, Surface; Antimalarials; Artemisinins; Cambodia; Child; Child, Preschool; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Quinolines; Treatment Failure; Young Adult | 2015 |
Clinical Efficacy of Dihydroartemisinin-Piperaquine for the Treatment of Uncomplicated Plasmodium falciparum Malaria at the China-Myanmar Border.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Child, Preschool; China; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Middle Aged; Myanmar; Quinolines; Treatment Outcome; Young Adult | 2015 |
Artemether-Lumefantrine Pharmacokinetics and Clinical Response Are Minimally Altered in Pregnant Ugandan Women Treated for Uncomplicated Falciparum Malaria.
Topics: Adolescent; Adult; Antimalarials; Artemether; Artemisinins; Cohort Studies; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Middle Aged; Pregnancy; Pregnancy Complications, Parasitic; Prospective Studies; Treatment Outcome; Uganda; Young Adult | 2015 |
Frequent Malaria Drives Progressive Vδ2 T-Cell Loss, Dysfunction, and CD16 Up-regulation During Early Childhood.
Topics: Artemisinins; Child, Preschool; Drug Combinations; GPI-Linked Proteins; Humans; Immune Tolerance; Infant; Longitudinal Studies; Malaria, Falciparum; Plasmodium falciparum; Pyrimethamine; Quinolines; Receptors, Antigen, T-Cell, gamma-delta; Receptors, IgG; Sulfadoxine; T-Lymphocyte Subsets; Up-Regulation | 2016 |
Antibody profiles to plasmodium merozoite surface protein-1 in Cambodian adults during an active surveillance cohort with nested treatment study.
Topics: Adult; Antibodies, Protozoan; Antigens, Protozoan; Artemisinins; Enzyme-Linked Immunosorbent Assay; Female; Humans; Malaria; Malaria, Falciparum; Male; Merozoite Surface Protein 1; Plasmodium falciparum; Plasmodium vivax; Young Adult | 2016 |
Primaquine to reduce transmission of Plasmodium falciparum malaria in Mali: a single-blind, dose-ranging, adaptive randomised phase 2 trial.
Topics: Animals; Anopheles; Antimalarials; Artemisinins; Drug Administration Schedule; Drug Therapy, Combination; Humans; Malaria, Falciparum; Mali; Primaquine; Quinolines; Single-Blind Method | 2016 |
Effective Antimalarial Chemoprevention in Childhood Enhances the Quality of CD4+ T Cells and Limits Their Production of Immunoregulatory Interleukin 10.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; CD4-Positive T-Lymphocytes; Chemoprevention; Child, Preschool; Female; Humans; Infant; Interleukin-10; Malaria, Falciparum; Male; Quinolines; Uganda; Young Adult | 2016 |
Malaria illness mediated by anaemia lessens cognitive development in younger Ugandan children.
Topics: Age Factors; Anemia; Antimalarials; Artemisinins; Child, Preschool; Cognition; Cognition Disorders; Coinfection; Drug Combinations; Female; Humans; Infant; Malaria, Falciparum; Male; Pyrimethamine; Quinolines; Risk Factors; Sulfadoxine; Trimethoprim, Sulfamethoxazole Drug Combination; Uganda | 2016 |
Clinical illness and outcomes in Nigerian children with late-appearing anaemia after artemisinin-based combination treatments of uncomplicated falciparum malaria.
Topics: Adolescent; Amodiaquine; Anemia; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Nigeria; Prognosis; Quinolines; Risk Factors; Time Factors; Treatment Outcome | 2016 |
Intermittent Preventive Treatment with Dihydroartemisinin-Piperaquine in Ugandan Schoolchildren Selects for Plasmodium falciparum Transporter Polymorphisms That Modify Drug Sensitivity.
Topics: Adolescent; Antimalarials; Artemisinins; Child; Female; Humans; Malaria, Falciparum; Male; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Polymorphism, Genetic; Pre-Exposure Prophylaxis; Protozoan Proteins; Quinolines; Uganda | 2016 |
Artemether-Lumefantrine versus Dihydroartemisinin-Piperaquine for Treatment of Uncomplicated Plasmodium falciparum Malaria in Children Aged Less than 15 Years in Guinea-Bissau - An Open-Label Non-Inferiority Randomised Clinical Trial.
Topics: Antimalarials; Artemether; Artemisinins; Child; Ethanolamines; Fluorenes; Guinea-Bissau; Humans; Lumefantrine; Malaria, Falciparum; Quinolines; Treatment Outcome | 2016 |
The Gametocytocidal Efficacy of Different Single Doses of Primaquine with Dihydroartemisinin-piperaquine in Asymptomatic Parasite Carriers in The Gambia: A Randomized Controlled Trial.
Topics: Adolescent; Antimalarials; Artemisinins; Asymptomatic Diseases; Carrier State; Child; Drug Therapy, Combination; Female; Gambia; Humans; Malaria, Falciparum; Male; Plasmodium falciparum; Primaquine; Quinolines; Treatment Outcome | 2016 |
Short-term Impact of Mass Drug Administration With Dihydroartemisinin Plus Piperaquine on Malaria in Southern Province Zambia: A Cluster-Randomized Controlled Trial.
Topics: Antimalarials; Artemisinins; Chemoprevention; Child, Preschool; Drug Therapy; Family Characteristics; Female; Humans; Incidence; Infant; Malaria, Falciparum; Male; Prevalence; Quinolines; Treatment Outcome; Zambia | 2016 |
Piperaquine Population Pharmacokinetics and Cardiac Safety in Cambodia.
Topics: Antimalarials; Arrhythmias, Cardiac; Artemisinins; Cambodia; Cardiotoxicity; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Myocardial Contraction; Plasmodium falciparum; Quinolines | 2017 |
Artemether-lumefantrine versus dihydroartemisinin-piperaquine for treating uncomplicated malaria: a randomized trial to guide policy in Uganda.
Topics: Antimalarials; Artemether; Artemisinins; Child; Child, Preschool; Drug Therapy, Combination; Ethanolamines; Fluorenes; Health Policy; Humans; Infant; Lumefantrine; Malaria, Falciparum; Quinolines; Uganda | 2008 |
Pharmacokinetics of a five-day oral dihydroartemisinin monotherapy regimen in patients with uncomplicated falciparum malaria.
Topics: Administration, Oral; Adolescent; Adult; Antimalarials; Area Under Curve; Artemisinins; Female; Humans; Malaria, Falciparum; Male; Metabolic Clearance Rate; Middle Aged | 2008 |
[Efficacy of dihydroartemisinin-piperaquine and artemether-lumefantrine in the treatment of uncomplicated falciparum malaria in Hainan, China].
Topics: Adolescent; Adult; Aged; Animals; Antimalarials; Artemether; Artemisinins; Child; Child, Preschool; China; Dose-Response Relationship, Drug; Drug Combinations; Ethanolamines; Female; Fluorenes; Follow-Up Studies; Humans; Infant; Lumefantrine; Malaria, Falciparum; Male; Middle Aged; Quinolines; Treatment Outcome; Young Adult | 2008 |
A randomized trial to monitor the efficacy and effectiveness by QT-NASBA of artemether-lumefantrine versus dihydroartemisinin-piperaquine for treatment and transmission control of uncomplicated Plasmodium falciparum malaria in western Kenya.
Topics: Animals; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Blood; Child; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Infant; Kenya; Malaria, Falciparum; Male; Microscopy; Parasitemia; Plasmodium falciparum; Quinolines; Self-Sustained Sequence Replication; Treatment Outcome | 2008 |
A trial of combination antimalarial therapies in children from Papua New Guinea.
Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Child, Preschool; Chloroquine; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Infant; Kaplan-Meier Estimate; Lumefantrine; Malaria, Falciparum; Malaria, Vivax; Male; Proportional Hazards Models; Pyrimethamine; Quinolines; Recurrence; Sulfadoxine | 2008 |
Open label randomized comparison of dihydroartemisinin-piperaquine and artesunate-amodiaquine for the treatment of uncomplicated Plasmodium falciparum malaria in central Vietnam.
Topics: Adolescent; Adult; Amodiaquine; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Combinations; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Pilot Projects; Quinolines; Treatment Outcome; Vietnam; Young Adult | 2009 |
Pharmacokinetics of chlorproguanil, dapsone, artesunate and their major metabolites in patients during treatment of acute uncomplicated Plasmodium falciparum malaria.
Topics: Adult; Antimalarials; Area Under Curve; Artemisinins; Artesunate; Dapsone; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Drug Therapy, Combination; Female; Gambia; Humans; Malaria, Falciparum; Malawi; Male; Middle Aged; Parasitic Sensitivity Tests; Proguanil; Time Factors | 2009 |
A randomized, controlled trial of artemisinin-piperaquine vs dihydroartemisinin-piperaquine phosphate in treatment of falciparum malaria.
Topics: Adolescent; Adult; Anti-Infective Agents; Antimalarials; Artemisinins; Drug Combinations; Female; Humans; Integrative Medicine; Malaria, Falciparum; Male; Quinolines; Treatment Outcome; Young Adult | 2009 |
Artemisinin resistance in Plasmodium falciparum malaria.
Topics: Administration, Oral; Adolescent; Adult; Animals; Antimalarials; Artemisinins; Artesunate; Drug Resistance; Drug Therapy, Combination; Follow-Up Studies; Humans; Hypoxanthine; Inhibitory Concentration 50; Malaria, Falciparum; Mefloquine; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Polymorphism, Genetic; Recurrence; Young Adult | 2009 |
Artemether-lumefantrine versus dihydroartemisinin-piperaquine for falciparum malaria: a longitudinal, randomized trial in young Ugandan children.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child, Preschool; Drug Combinations; Ethanolamines; Fluorenes; Humans; Infant; Malaria, Falciparum; Quinolines; Treatment Outcome; Uganda | 2009 |
Dihydroartemisinin-piperaquine and artemether-lumefantrine for treating uncomplicated malaria in African children: a randomised, non-inferiority trial.
Topics: Africa; Antiparasitic Agents; Artemether; Artemisinins; Child, Preschool; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Infant; Lumefantrine; Malaria; Malaria, Falciparum; Plasmodium falciparum; Polymerase Chain Reaction; Quinolines; Time Factors | 2009 |
Safety and tolerability of artemether-lumefantrine versus dihydroartemisinin-piperaquine for malaria in young HIV-infected and uninfected children.
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Follow-Up Studies; HIV Infections; Humans; Infant; Longitudinal Studies; Malaria, Falciparum; Male; Quinolines; Risk Factors; Treatment Outcome; Uganda | 2009 |
Dihydroartemisinin-piperaquine versus artemether-lumefantrine, in the treatment of uncomplicated Plasmodium falciparum malaria in central Sudan.
Topics: Antimalarials; Artemisinins; Child; Child, Preschool; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Plasmodium falciparum; Quinolines; Sudan; Treatment Outcome | 2010 |
An open-label, randomised study of dihydroartemisinin-piperaquine versus artesunate-mefloquine for falciparum malaria in Asia.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Artesunate; Asia; Child; Child, Preschool; Female; Humans; Infant; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Quinolines; Young Adult | 2010 |
Population pharmacokinetics and pharmacodynamics of artemether and lumefantrine during combination treatment in children with uncomplicated falciparum malaria in Tanzania.
Topics: Antimalarials; Artemether; Artemisinins; Body Temperature; Child; Child, Preschool; Ethanolamines; Female; Fluorenes; Humans; Infant; Lumefantrine; Malaria, Falciparum; Male; Tanzania; Treatment Outcome | 2010 |
A phase III, randomized, non-inferiority trial to assess the efficacy and safety of dihydroartemisinin-piperaquine in comparison with artesunate-mefloquine in patients with uncomplicated Plasmodium falciparum malaria in southern Laos.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Laos; Malaria, Falciparum; Male; Mefloquine; Quinolines; Young Adult | 2010 |
Safety and efficacy of dihydroartemisinin-piperaquine versus artemether-lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria in Zambian children.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child, Preschool; Drug Combinations; Ethanolamines; Fluorenes; Humans; Infant; Malaria, Falciparum; Plasmodium falciparum; Quinolines; Treatment Outcome; Zambia | 2011 |
Population pharmacokinetics of artesunate and dihydroartemisinin in pregnant and non-pregnant women with malaria.
Topics: Administration, Oral; Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Case-Control Studies; Democratic Republic of the Congo; Female; Humans; Malaria, Falciparum; Models, Biological; Models, Statistical; Pregnancy; Pregnancy Complications, Parasitic; Young Adult | 2011 |
A small amount of fat does not affect piperaquine exposure in patients with malaria.
Topics: Adolescent; Adult; Aged; Artemisinins; Chromatography, Liquid; Dietary Fats; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Quinolines; Tandem Mass Spectrometry; Young Adult | 2011 |
Comparative study of the efficacy and tolerability of dihydroartemisinin-piperaquine-trimethoprim versus artemether-lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria in Cameroon, Ivory Coast and Senegal.
Topics: Adolescent; Adult; Animals; Antimalarials; Artemether; Artemisinins; Cameroon; Child; Child, Preschool; Cote d'Ivoire; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Male; Middle Aged; Quinolines; Senegal; Treatment Outcome; Trimethoprim; Young Adult | 2011 |
Multicentric assessment of the efficacy and tolerability of dihydroartemisinin-piperaquine compared to artemether-lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria in sub-Saharan Africa.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Cameroon; Child; Child, Preschool; Cote d'Ivoire; Drug Combinations; Ethanolamines; Female; Fluorenes; Humans; Malaria, Falciparum; Male; Middle Aged; Quinolines; Senegal; Treatment Outcome; Young Adult | 2011 |
[Efficacy of compound dihydroartemisinin/piperaquine in treatment of uncomplicated falciparum malaria in Myanmar].
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Myanmar; Quinolines; Tablets; Treatment Outcome; Young Adult | 2011 |
A head-to-head comparison of four artemisinin-based combinations for treating uncomplicated malaria in African children: a randomized trial.
Topics: Adult; Africa South of the Sahara; Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Drug Combinations; Ethanolamines; Female; Fluorenes; Humans; Malaria, Falciparum; Male | 2011 |
Declining responsiveness of Plasmodium falciparum infections to artemisinin-based combination treatments on the Kenyan coast.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child, Preschool; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Infant; Kenya; Malaria, Falciparum; Male; Plasmodium falciparum; Quinolines; Survival Rate | 2011 |
Similar efficacy and safety of artemether-lumefantrine (Coartem®) in African infants and children with uncomplicated falciparum malaria across different body weight ranges.
Topics: Age Factors; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Body Weight; Child; Child, Preschool; Drug Combinations; Ethanolamines; Female; Fluorenes; Humans; Infant; Lumefantrine; Malaria, Falciparum; Male; Plasmodium falciparum; Polymerase Chain Reaction; Time Factors; Treatment Outcome | 2011 |
A simplified intravenous artesunate regimen for severe malaria.
Topics: Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Double-Blind Method; Female; Humans; Kaplan-Meier Estimate; Malaria, Falciparum; Male; Parasite Load; Parasitemia; Time Factors; Treatment Outcome | 2012 |
Randomized, double-blind, placebo-controlled trial of monthly versus bimonthly dihydroartemisinin-piperaquine chemoprevention in adults at high risk of malaria.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Chemoprevention; Dietary Fats; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Hematocrit; Humans; Malaria, Falciparum; Malaria, Vivax; Male; Middle Aged; Placebos; Plasmodium falciparum; Plasmodium vivax; Quinolines; Risk; Thailand | 2012 |
Population pharmacokinetics and pharmacodynamics of piperaquine in children with uncomplicated falciparum malaria.
Topics: Artemisinins; Body Weight; Burkina Faso; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Quinolines | 2012 |
Therapeutic efficacy and safety of dihydroartemisinin-piperaquine versus artesunate-mefloquine in uncomplicated Plasmodium falciparum malaria in India.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Artesunate; Asia; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Female; Humans; India; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Quinolines; Treatment Outcome; Young Adult | 2012 |
Pharmacokinetics and pharmacodynamics of oral artesunate monotherapy in patients with uncomplicated Plasmodium falciparum malaria in western Cambodia.
Topics: Administration, Oral; Adult; Antimalarials; Artemisinins; Artesunate; Cambodia; Drug Administration Schedule; Female; Humans; Malaria, Falciparum; Male; Parasitemia; Plasmodium falciparum; Severity of Illness Index | 2012 |
In vivo susceptibility of Plasmodium falciparum to artesunate in Binh Phuoc Province, Vietnam.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Child; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Plasmodium falciparum; Quinolines; Treatment Outcome; Vietnam; Young Adult | 2012 |
The effect of primaquine on gametocyte development and clearance in the treatment of uncomplicated falciparum malaria with dihydroartemisinin-piperaquine in South sumatra, Western indonesia: an open-label, randomized, controlled trial.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Drug Therapy, Combination; Female; Glucosephosphate Dehydrogenase; Humans; Indonesia; Malaria, Falciparum; Male; Parasitemia; Plasmodium falciparum; Quinolines; Treatment Outcome; Young Adult | 2013 |
Efficacy of quinine, artemether-lumefantrine and dihydroartemisinin-piperaquine as rescue treatment for uncomplicated malaria in Ugandan children.
Topics: Antimalarials; Artemether; Artemisinins; Child, Preschool; Ethanolamines; Fluorenes; Humans; Infant; Lumefantrine; Malaria, Falciparum; Male; Quinine; Quinolines; Safety; Treatment Outcome; Uganda | 2013 |
The effects of ACT treatment and TS prophylaxis on Plasmodium falciparum gametocytemia in a cohort of young Ugandan children.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Fluorenes; HIV Infections; Humans; Infant; Longitudinal Studies; Malaria, Falciparum; Multivariate Analysis; Parasitemia; Plasmodium falciparum; Post-Exposure Prophylaxis; Prevalence; Proportional Hazards Models; Quinolines; Risk Factors; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination; Trophozoites; Uganda | 2013 |
Efficacy and safety of dihydroartemisinin-piperaquine (Artekin) in Cambodian children and adults with uncomplicated falciparum malaria.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Cambodia; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Quinolines; Sesquiterpenes; Treatment Outcome | 2002 |
Penetration of dihydroartemisinin into cerebrospinal fluid after administration of intravenous artesunate in severe falciparum malaria.
Topics: Adolescent; Adult; Artemisinins; Artesunate; Chromatography, High Pressure Liquid; Female; Half-Life; Humans; Injections, Intravenous; Malaria, Cerebral; Malaria, Falciparum; Male; Middle Aged; Sesquiterpenes | 2003 |
[Study on treatment of multi-drug resistant falciparum malaria by using a combination of dihydroartemisinin and pyronaridine].
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Child; Child, Preschool; Double-Blind Method; Drug Resistance, Multiple; Drug Therapy, Combination; Humans; Infant; Malaria, Falciparum; Middle Aged; Naphthyridines; Sesquiterpenes | 2002 |
A comparative clinical trial of combinations of dihydroartemisinin plus azithromycin and dihydroartemisinin plus mefloquine for treatment of multidrug resistant falciparum malaria.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Azithromycin; Drug Combinations; Drug Resistance, Multiple; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Sesquiterpenes; Statistics, Nonparametric; Thailand | 2002 |
An open randomized clinical trial of Artecom vs artesunate-mefloquine in the treatment of acute uncomplicated falciparum malaria in Thailand.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Artesunate; Child; Drug Combinations; Drug Resistance, Multiple; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Quinolines; Sesquiterpenes; Thailand; Trimethoprim | 2002 |
Rectal dihydroartemisinin versus intravenous quinine in the treatment of severe malaria: a randomised clinical trial.
Topics: Administration, Rectal; Adolescent; Adult; Antimalarials; Artemisinins; Child; Child, Preschool; Humans; Infusions, Intravenous; Malaria, Falciparum; Middle Aged; Quinine; Sesquiterpenes | 2000 |
Comparative clinical trial of two-fixed combinations dihydroartemisinin-napthoquine-trimethoprim (DNP) and artemether-lumefantrine (Coartem/Riamet) in the treatment of acute uncomplicated falciparum malaria in Thailand.
Topics: Adolescent; Adult; Antimalarials; Artemether; Artemisinins; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Male; Middle Aged; Sesquiterpenes; Thailand; Treatment Outcome; Trimethoprim | 2003 |
Safety evaluation of fixed combination piperaquine plus dihydroartemisinin (Artekin) in Cambodian children and adults with malaria.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Blood Glucose; Cambodia; Child; Child, Preschool; Drug Combinations; Drug Evaluation; Electrocardiography; Heart Rate; Hematocrit; Humans; Infant; Infant, Newborn; Malaria, Falciparum; Malaria, Vivax; Middle Aged; Quinolines; Sesquiterpenes | 2004 |
Dihydroartemisinin-piperaquine against multidrug-resistant Plasmodium falciparum malaria in Vietnam: randomised clinical trial.
Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Combinations; Drug Resistance, Multiple; Female; Follow-Up Studies; Humans; Malaria, Falciparum; Male; Pilot Projects; Plasmodium falciparum; Quinolines; Sesquiterpenes; Treatment Outcome; Trimethoprim; Vietnam | 2004 |
CV8, a new combination of dihydroartemisinin, piperaquine, trimethoprim and primaquine, compared with atovaquone-proguanil against falciparum malaria in Vietnam.
Topics: Adolescent; Adult; Aged; Animals; Antimalarials; Artemisinins; Atovaquone; Drug Combinations; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Naphthoquinones; Parasitemia; Plasmodium falciparum; Primaquine; Proguanil; Quinolines; Sesquiterpenes; Treatment Outcome; Trimethoprim; Vietnam | 2004 |
Randomized, controlled dose-optimization studies of dihydroartemisinin-piperaquine for the treatment of uncomplicated multidrug-resistant falciparum malaria in Thailand.
Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Drug Combinations; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Quinolines; Sesquiterpenes; Thailand | 2004 |
Comparison of the bioequivalence of three oral formulations of dihydroartemisinin based on ex vivo blood schizontocidal activities against Plasmodium falciparum.
Topics: Administration, Oral; Adult; Animals; Antimalarials; Area Under Curve; Artemisinins; Cells, Cultured; Chemistry, Pharmaceutical; Cross-Over Studies; Humans; Malaria, Falciparum; Male; Parasitemia; Plasmodium falciparum; Sesquiterpenes; Therapeutic Equivalency | 2004 |
Pharmacokinetic investigation on the therapeutic potential of artemotil (beta-arteether) in Thai patients with severe Plasmodium falciparum malaria.
Topics: Adult; Antimalarials; Area Under Curve; Artemisinins; Half-Life; Humans; Injections, Intramuscular; Malaria, Falciparum; Sesquiterpenes | 2004 |
Efficacy comparison between anti-malarial drugs in Africans presenting with mild malaria in the Central Republic of Africa: a preliminary study.
Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Central African Republic; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Parasitemia; Parasitic Sensitivity Tests; Patient Compliance; Plasmodium falciparum; Pyrimethamine; Quinine; Quinolines; Sesquiterpenes; Sulfadoxine; Treatment Outcome; Trimethoprim | 2005 |
Pharmacokinetics of the four combination regimens of dihydroartemisinin/mefloquine in acute uncomplicated falciparum malaria.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Animals; Antimalarials; Artemisinins; Drug Therapy, Combination; Humans; Malaria, Falciparum; Mefloquine; Sesquiterpenes | 2005 |
A randomized, controlled study of a simple, once-daily regimen of dihydroartemisinin-piperaquine for the treatment of uncomplicated, multidrug-resistant falciparum malaria.
Topics: Adolescent; Adult; Aged; Animals; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Drug Combinations; Drug Resistance, Multiple; Female; Humans; Infant; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Quinolines; Sesquiterpenes | 2005 |
An open randomized clinical trial of Artekin vs artesunate-mefloquine in the treatment of acute uncomplicated falciparum malaria.
Topics: Acute Disease; Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Drug Combinations; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Quinolines; Sesquiterpenes; Thailand; Treatment Outcome | 2005 |
Safety and efficacy of dihydroartemisinin/piperaquine (Artekin) for the treatment of uncomplicated Plasmodium falciparum malaria in Rwandan children.
Topics: Antimalarials; Artemisinins; Child, Preschool; Drug Combinations; Female; Humans; Leukocyte Count; Malaria, Falciparum; Male; Quinolines; Rwanda; Sesquiterpenes; Treatment Outcome | 2006 |
Efficacy and effectiveness of dihydroartemisinin-piperaquine versus artesunate-mefloquine in falciparum malaria: an open-label randomised comparison.
Topics: Adolescent; Animals; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Mefloquine; Myanmar; Plasmodium falciparum; Quinolines; Recurrence; Sesquiterpenes; Treatment Outcome | 2006 |
An open, randomized comparison of artesunate plus mefloquine vs. dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium falciparum malaria in the Lao People's Democratic Republic (Laos).
Topics: Administration, Oral; Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Child; Drug Therapy, Combination; Female; Humans; Laos; Malaria, Falciparum; Male; Mefloquine; Parasitemia; Quinolines; Recurrence; Sesquiterpenes; Treatment Failure; Treatment Outcome | 2006 |
The pharmacokinetics of artemether and lumefantrine in pregnant women with uncomplicated falciparum malaria.
Topics: Adolescent; Adult; Antimalarials; Area Under Curve; Artemether; Artemisinins; Drug Administration Schedule; Ethanolamines; Female; Fluorenes; Follow-Up Studies; Half-Life; Humans; Lumefantrine; Malaria, Falciparum; Male; Pregnancy; Pregnancy Outcome; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Recurrence; Remission Induction; Sesquiterpenes; Tablets; Thailand | 2006 |
The pharmacokinetics of intravenous artesunate in adults with severe falciparum malaria.
Topics: Administration, Oral; Adolescent; Adult; Age Factors; Antimalarials; Area Under Curve; Artemisinins; Artesunate; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electrochemistry; Female; Half-Life; Humans; Injections, Intravenous; Malaria, Falciparum; Male; Metabolic Clearance Rate; Middle Aged; Pilot Projects; Quinine; Sesquiterpenes; Severity of Illness Index; Thailand | 2006 |
Dihydroartemisinin suppository in moderately severe malaria: comparative efficacy of dihydroartemisinin suppository versus intramuscular artemeter followed by oral sulfadoxine-pyrimethamine in the management of moderately severe malaria in Nigerian childr
Topics: Antimalarials; Artemether; Artemisinins; Child; Child, Preschool; Drug Combinations; Humans; Infant; Injections, Intramuscular; Malaria, Falciparum; Nigeria; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Suppositories | 2007 |
A randomized open study to assess the efficacy and tolerability of dihydroartemisinin-piperaquine for the treatment of uncomplicated falciparum malaria in Cambodia.
Topics: Adolescent; Adult; Aged; Anemia; Antimalarials; Artemisinins; Artesunate; Cambodia; Child; Child, Preschool; Drug Therapy, Combination; Female; Genome, Protozoan; Humans; Infant; Malaria, Falciparum; Malaria, Vivax; Male; Mefloquine; Middle Aged; Quinolines; Recurrence; Sesquiterpenes; Treatment Outcome | 2007 |
Two fixed-dose artemisinin combinations for drug-resistant falciparum and vivax malaria in Papua, Indonesia: an open-label randomised comparison.
Topics: Adolescent; Adult; Anemia; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Child, Preschool; Diarrhea; Drug Administration Schedule; Drug Combinations; Drug Resistance, Multiple; Ethanolamines; Female; Fluorenes; Humans; Indonesia; Infant; Malaria, Falciparum; Malaria, Vivax; Male; Middle Aged; Prospective Studies; Quinolines; Recurrence; Sesquiterpenes; Treatment Outcome; Urticaria; Vomiting | 2007 |
Dihydroartemisinin-piperaquine versus artesunate-amodiaquine: superior efficacy and posttreatment prophylaxis against multidrug-resistant Plasmodium falciparum and Plasmodium vivax malaria.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Artesunate; Drug Resistance, Multiple; Drug Tolerance; Humans; Indonesia; Malaria, Falciparum; Malaria, Vivax; Plasmodium falciparum; Quinolines; Sesquiterpenes; Treatment Outcome | 2007 |
Pharmacokinetics of mefloquine with dihydroartemisinin as 2-day regimens in patients with uncomplicated falciparum malaria.
Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Drug Administration Schedule; Drug Therapy, Combination; Humans; Interviews as Topic; Malaria, Falciparum; Male; Mefloquine; Plasmodium falciparum; Sesquiterpenes; Treatment Outcome | 2007 |
Clinical efficacy of high dose monotherapy of oral dihydroartemisinin in uncomplicated falciparum malaria in viet nam.
Topics: Administration, Oral; Adolescent; Adult; Animals; Antimalarials; Artemisinins; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Sesquiterpenes; Treatment Outcome; Vietnam | 2007 |
Electrocardiographic safety evaluation of dihydroartemisinin piperaquine in the treatment of uncomplicated falciparum malaria.
Topics: Arrhythmias, Cardiac; Artemisinins; Electrocardiography; Humans; Malaria, Falciparum; Sesquiterpenes | 2007 |
Pharmacokinetics and efficacy of piperaquine and chloroquine in Melanesian children with uncomplicated malaria.
Topics: Animals; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Malaria, Vivax; Male; Papua New Guinea; Plasmodium falciparum; Plasmodium vivax; Pyrimethamine; Quinolines; Sesquiterpenes; Sulfadoxine; Treatment Outcome | 2008 |
A randomised controlled trial to assess the efficacy of dihydroartemisinin-piperaquine for the treatment of uncomplicated falciparum malaria in Peru.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Peru; Quinolines; Sesquiterpenes | 2007 |
Population pharmacokinetics of piperaquine after two different treatment regimens with dihydroartemisinin-piperaquine in patients with Plasmodium falciparum malaria in Thailand.
Topics: Adolescent; Adult; Animals; Antimalarials; Area Under Curve; Artemisinins; Child; Child, Preschool; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Quinolines; Thailand; Treatment Outcome | 2008 |
[Randomised comparison on the treatment of falciparum malaria with dihydroartemisinin and piperaquine].
Topics: Adult; Antimalarials; Artemisinins; Drug Evaluation; Female; Humans; Malaria, Falciparum; Male; Quinolines; Sesquiterpenes | 1993 |
A pharmacokinetic and pharmacodynamic study of intravenous vs oral artesunate in uncomplicated falciparum malaria.
Topics: Administration, Oral; Adult; Antimalarials; Artemisinins; Artesunate; Female; Humans; Injections, Intravenous; Malaria, Falciparum; Male; Reference Values; Sesquiterpenes; Time Factors; Vietnam | 1998 |
Pharmacokinetics of oral artemether in Thai patients with uncomplicated falciparum malaria.
Topics: Administration, Oral; Adolescent; Adult; Antimalarials; Area Under Curve; Artemether; Artemisinins; Chromatography, High Pressure Liquid; Follow-Up Studies; Humans; Malaria, Falciparum; Sesquiterpenes; Thailand | 1998 |
Plasma concentrations of artemether and its major plasma metabolite, dihydroartemisinin, following a 5-day regimen of oral artemether, in patients with uncomplicated falciparum malaria.
Topics: Acute Disease; Adolescent; Adult; Antimalarials; Artemether; Artemisinins; Drug Resistance, Multiple; Follow-Up Studies; Humans; Malaria, Falciparum; Male; Middle Aged; Sesquiterpenes | 1998 |
Pharmacokinetics of intramuscular artemether in patients with severe falciparum malaria with or without acute renal failure.
Topics: Acute Kidney Injury; Adolescent; Adult; Antimalarials; Artemether; Artemisinins; Humans; Kidney; Malaria, Falciparum; Male; Metabolic Clearance Rate; Middle Aged; Sesquiterpenes; Treatment Outcome | 1998 |
Declining concentrations of dihydroartemisinin in plasma during 5-day oral treatment with artesunate for Falciparum malaria.
Topics: Adult; Antimalarials; Artemisinins; Artesunate; Chromatography, High Pressure Liquid; Electrochemistry; Humans; Malaria, Falciparum; Male; Sesquiterpenes | 1999 |
Multiple dose pharmacokinetics of artemether in Chinese patients with uncomplicated falciparum malaria.
Topics: Adolescent; Adult; Antimalarials; Artemether; Artemisinins; China; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Male; Middle Aged; Models, Chemical; Sesquiterpenes; Time Factors | 1999 |
Comparative clinical trial of four regimens of dihydroartemisinin-mefloquine in multidrug-resistant falciparum malaria.
Topics: Administration, Oral; Adolescent; Adult; Antimalarials; Artemisinins; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance, Multiple; Drug Therapy, Combination; Humans; Malaria, Falciparum; Male; Mefloquine; Sesquiterpenes; Treatment Outcome | 1999 |
Pharmacokinetics and bioequivalence evaluation of three commercial tablet formulations of mefloquine when given in combination with dihydroartemisinin in patients with acute uncomplicated falciparum malaria.
Topics: Acute Disease; Adolescent; Adult; Antimalarials; Artemisinins; Biological Availability; Chromatography, High Pressure Liquid; Drug Therapy, Combination; Humans; Malaria, Falciparum; Male; Mefloquine; Recurrence; Sesquiterpenes; Tablets; Thailand; Therapeutic Equivalency; Time Factors | 2000 |
Dose findings of dihydroartemisinin in treatment of falciparum malaria.
Topics: Administration, Oral; Adolescent; Adult; Aged; Antimalarials; Artemisinins; Child; China; Dose-Response Relationship, Drug; Drug Resistance; Fever; Follow-Up Studies; Humans; Malaria, Falciparum; Middle Aged; Sesquiterpenes; Time Factors | 1999 |
Pharmacokinetics and pharmacodynamics of intravenous artesunate in severe falciparum malaria.
Topics: Adult; Antimalarials; Area Under Curve; Artemisinins; Artesunate; Female; Half-Life; Humans; Infusions, Intravenous; Malaria, Falciparum; Male; Sesquiterpenes | 2001 |
Oral bioavailability of dihydroartemisinin in Vietnamese volunteers and in patients with falciparum malaria.
Topics: Administration, Oral; Adult; Antimalarials; Artemisinins; Biological Availability; Cross-Over Studies; Dose-Response Relationship, Drug; Half-Life; Humans; Injections, Intravenous; Malaria, Falciparum; Metabolic Clearance Rate; Sesquiterpenes; Time Factors; Vietnam | 2001 |
Efficacy of dihydroartemisinin-mefloquine on acute uncomplicated falciparum malaria.
Topics: Acute Disease; Adolescent; Adult; Animals; Antimalarials; Artemisinins; Child; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Nausea; Plasmodium falciparum; Sesquiterpenes; Treatment Outcome; Vomiting | 2001 |
The pharmacokinetic properties of intramuscular artesunate and rectal dihydroartemisinin in uncomplicated falciparum malaria.
Topics: Administration, Rectal; Adult; Antimalarials; Area Under Curve; Artemisinins; Artesunate; Confidence Intervals; Cross-Over Studies; Female; Humans; Injections, Intramuscular; Injections, Intravenous; Malaria, Falciparum; Male; Sesquiterpenes; Statistics, Nonparametric | 2002 |
Comparison of oral artesunate and dihydroartemisinin antimalarial bioavailabilities in acute falciparum malaria.
Topics: Acute Disease; Adolescent; Adult; Aged; Antimalarials; Area Under Curve; Artemisinins; Artesunate; Biological Availability; Chromatography, High Pressure Liquid; Cross-Over Studies; Double-Blind Method; Female; Half-Life; Humans; Malaria, Falciparum; Male; Middle Aged; Sesquiterpenes; Spectrophotometry, Ultraviolet; Vietnam | 2002 |
210 other study(ies) available for artenimol and Plasmodium falciparum Malaria
Article | Year |
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Target Elucidation by Cocrystal Structures of NADH-Ubiquinone Oxidoreductase of Plasmodium falciparum (PfNDH2) with Small Molecule To Eliminate Drug-Resistant Malaria.
Topics: Allosteric Regulation; Animals; Drug Resistance; Electron Transport Complex I; Malaria, Falciparum; Plasmodium falciparum; Protein Conformation | 2017 |
Discovery of fast-acting dual-stage antimalarial agents by profiling pyridylvinylquinoline chemical space via copper catalyzed azide-alkyne cycloadditions.
Topics: Antimalarials; Azides; Copper; Cycloaddition Reaction; Hep G2 Cells; Humans; Life Cycle Stages; Malaria, Falciparum; Plasmodium falciparum; Quinolines | 2021 |
Discovery of Novel
Topics: Animals; Antimalarials; Drug Design; Drug Repositioning; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Stability; Histone Deacetylase Inhibitors; Hydroxamic Acids; Malaria, Falciparum; Mice; Microsomes, Liver; Molecular Structure; Plasmodium falciparum; Structure-Activity Relationship | 2021 |
Discovery and development of 2-aminobenzimidazoles as potent antimalarials.
Topics: Antimalarials; Benzimidazoles; Dose-Response Relationship, Drug; Drug Discovery; HEK293 Cells; Humans; Malaria, Falciparum; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship | 2021 |
Procainamide-SAHA Fused Inhibitors of hHDAC6 Tackle Multidrug-Resistant Malaria Parasites.
Topics: Antimalarials; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Histone Deacetylase 6; Histone Deacetylase Inhibitors; Hydroxamic Acids; Malaria, Falciparum; Molecular Structure; Plasmodium falciparum; Procainamide; Structure-Activity Relationship | 2021 |
Structure-activity relationships of the antimalarial agent artemisinin. 8. design, synthesis, and CoMFA studies toward the development of artemisinin-based drugs against leishmaniasis and malaria.
Topics: Animals; Antimalarials; Antiprotozoal Agents; Artemisinins; Clone Cells; Drug Design; Inhibitory Concentration 50; L-Lactate Dehydrogenase; Leishmania donovani; Malaria, Falciparum; Models, Molecular; Molecular Conformation; Plasmodium falciparum; Sesquiterpenes; Static Electricity; Stereoisomerism; Structure-Activity Relationship | 2003 |
Spiro and dispiro-1,2,4-trioxolanes as antimalarial peroxides: charting a workable structure-activity relationship using simple prototypes.
Topics: Adamantane; Animals; Antimalarials; Cell Line, Tumor; Drug Resistance; Half-Life; Malaria; Malaria, Falciparum; Mice; Micronucleus Tests; Ozone; Peroxides; Plasmodium berghei; Rats; Spiro Compounds; Structure-Activity Relationship | 2005 |
In vitro antimalarial activity of azithromycin, artesunate, and quinine in combination and correlation with clinical outcome.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Azithromycin; Clinical Trials, Phase II as Topic; Drug Evaluation; Drug Interactions; Drug Therapy, Combination; Humans; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinine; Sesquiterpenes | 2007 |
In vitro activities of piperaquine, lumefantrine, and dihydroartemisinin in Kenyan Plasmodium falciparum isolates and polymorphisms in pfcrt and pfmdr1.
Topics: Animals; Antimalarials; Artemisinins; Ethanolamines; Fluorenes; Genotype; Humans; Lumefantrine; Malaria, Falciparum; Membrane Transport Proteins; Microbial Sensitivity Tests; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Quinolines | 2009 |
Cytotoxic and antiplasmodial compounds from the roots of Strophioblachia fimbricalyx.
Topics: Animals; Antimalarials; Antineoplastic Agents, Phytogenic; Chlorocebus aethiops; Drug Screening Assays, Antitumor; Euphorbiaceae; Female; Free Radical Scavengers; Humans; Malaria, Falciparum; Molecular Structure; Phenanthrenes; Plant Roots; Plants, Medicinal; Plasmodium falciparum; Thailand | 2009 |
The structure-activity relationship of the antimalarial ozonide arterolane (OZ277).
Topics: Animals; Antimalarials; Heterocyclic Compounds, 1-Ring; Malaria, Falciparum; Mice; Molecular Conformation; Parasitic Sensitivity Tests; Peroxides; Plasmodium falciparum; Spiro Compounds; Stereoisomerism; Structure-Activity Relationship | 2010 |
Transforming rhinacanthin analogues from potent anticancer agents into potent antimalarial agents.
Topics: Animals; Antimalarials; Antineoplastic Agents; Cell Survival; Chlorocebus aethiops; Electron Transport Complex III; Erythrocytes; Inhibitory Concentration 50; Malaria, Falciparum; Male; Mitochondrial Membranes; Naphthoquinones; Plasmodium falciparum; Rats; Rats, Wistar; Saccharomyces cerevisiae; Structure-Activity Relationship; Vero Cells | 2010 |
Investigations into the role of the Plasmodium falciparum SERCA (PfATP6) L263E mutation in artemisinin action and resistance.
Topics: Animals; Antimalarials; Artemisinins; Inhibitory Concentration 50; Malaria, Falciparum; Mutation; Plasmodium falciparum; Reverse Transcriptase Polymerase Chain Reaction; Sarcoplasmic Reticulum Calcium-Transporting ATPases | 2010 |
Synthesis and evaluation of the antimalarial, anticancer, and caspase 3 activities of tetraoxane dimers.
Topics: Antimalarials; Antineoplastic Agents; Caspase 3; Cell Line, Tumor; Dimerization; Humans; Malaria, Falciparum; Neoplasms; Plasmodium falciparum; Tetraoxanes | 2013 |
Efficacy and safety of artemether-lumefantrine and dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium falciparum malaria and prevalence of molecular markers associated with artemisinin and partner drug resistance in Uganda.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Biomarkers; Drug Resistance; Humans; Malaria, Falciparum; Plasmodium falciparum; Quinolines; Uganda | 2021 |
Evidence for the early emergence of piperaquine-resistant Plasmodium falciparum malaria and modeling strategies to mitigate resistance.
Topics: Alleles; Animals; Antimalarials; Artemisinins; Chloroquine; Computer Simulation; Drug Resistance, Multiple; Humans; Malaria, Falciparum; Membrane Transport Proteins; Piperazines; Plasmodium falciparum; Protozoan Proteins; Quinolines | 2022 |
Evaluations of candidate markers of dihydroartemisinin-piperaquine resistance in Plasmodium falciparum isolates from the China-Myanmar, Thailand-Myanmar, and Thailand-Cambodia borders.
Topics: Antimalarials; Artemisinins; Biomarkers; Cambodia; Chloroquine; Drug Resistance; Humans; Malaria, Falciparum; Membrane Transport Proteins; Myanmar; Piperazines; Plasmodium falciparum; Protozoan Proteins; Quinolines; Thailand | 2022 |
Observation of Malaria Treatment with Dihydroartemisinin-Piperaquine Combination at Primary Health Care
Topics: Antimalarials; Artemisinins; Drug Therapy, Combination; Humans; Malaria; Malaria, Falciparum; Malaria, Vivax; Piperazines; Primary Health Care; Quinolines; Treatment Outcome | 2022 |
Artesunate and dihydroartemisinin-piperaquine treatment failure in a severe Plasmodium falciparum malaria case imported from Republic of Côte d'Ivoire.
Topics: Aged; Antimalarials; Artemisinins; Artesunate; Cote d'Ivoire; Drug Combinations; Humans; Malaria; Malaria, Falciparum; Male; Piperazines; Plasmodium falciparum; Quinolines; Treatment Failure | 2022 |
Piperaquine Pharmacokinetic and Pharmacodynamic Profiles in Healthy Volunteers of Papua New Guinea after Administration of Three-Monthly Doses of Dihydroartemisinin-Piperaquine.
Topics: Adult; Antimalarials; Artemisinins; Female; Healthy Volunteers; Humans; Long QT Syndrome; Longitudinal Studies; Malaria, Falciparum; Male; Papua New Guinea; Piperazines; Quinolines | 2022 |
Efficacy of Artemether-Lumefantrine and Dihydroartemisinin-Piperaquine for the Treatment of Uncomplicated Plasmodium falciparum Malaria among Children in Western Kenya, 2016 to 2017.
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Drug Combinations; Ethanolamines; Fluorenes; Folic Acid Antagonists; Humans; Infant; Kenya; Malaria; Malaria, Falciparum; Piperazines; Plasmodium falciparum; Quinolines; Reinfection | 2022 |
Naturally Acquired Kelch13 Mutations in Plasmodium falciparum Strains Modulate
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Drug Resistance; Drug Tolerance; Hyperoxia; Malaria, Falciparum; Mutation; Parasites; Plasmodium falciparum; Protozoan Proteins | 2022 |
Piperaquine-resistant PfCRT mutations differentially impact drug transport, hemoglobin catabolism and parasite physiology in Plasmodium falciparum asexual blood stages.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Heme; Hemoglobins; Humans; Malaria, Falciparum; Membrane Transport Proteins; Mutation; Parasites; Plasmodium falciparum; Protozoan Proteins | 2022 |
A Novel
Topics: Antimalarials; Chloroquine; Humans; Malaria, Falciparum; Plasmodium falciparum; Primaquine | 2022 |
Therapeutic efficacy of dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium vivax malaria in Seacha area, Arbaminch Zuria District, South West Ethiopia.
Topics: Antimalarials; Artemisinins; Ethiopia; Humans; Malaria; Malaria, Falciparum; Malaria, Vivax | 2022 |
Assessment of artemisinin tolerance in Plasmodium falciparum clinical isolates in children with uncomplicated malaria in Ghana.
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Drug Combinations; Drug Tolerance; Ghana; Humans; Lumefantrine; Malaria; Malaria, Falciparum; Plasmodium falciparum | 2023 |
Comparative efficacy of sulphadoxine-pyrimethamine and dihydroartemisinin-piperaquine against malaria infection during late-stage pregnancy in mice.
Topics: Animals; Antimalarials; Drug Combinations; Drug Therapy, Combination; Female; Malaria; Malaria, Falciparum; Mice; Plasmodium berghei; Pregnancy; Pyrimethamine | 2023 |
Design, Implementation, and Coordination of Malaria Therapeutic Efficacy Studies in Nigeria in 2018.
Topics: Amodiaquine; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Child; Drug Combinations; Ethanolamines; Fluorenes; Humans; Malaria; Malaria, Falciparum; Nigeria | 2023 |
Prevalence of mutations in the cysteine desulfurase IscS (Pfnfs1) gene in recurrent Plasmodium falciparum infections following artemether-lumefantrine (AL) and dihydroartemisinin-piperaquine (DP) treatment in Matayos, Western Kenya.
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Drug Combinations; Humans; Kenya; Lumefantrine; Malaria; Malaria, Falciparum; Mutation; Plasmodium falciparum; Prevalence; Quinolines; Reinfection | 2023 |
Ex vivo RSA and pfkelch13 targeted-amplicon deep sequencing reveal parasites susceptibility to artemisinin in Senegal, 2017.
Topics: Animals; Antimalarials; Artemisinins; Drug Resistance; High-Throughput Nucleotide Sequencing; Humans; Malaria, Falciparum; Mutation; Parasites; Plasmodium falciparum; Protozoan Proteins; Senegal; Uganda | 2023 |
Effectiveness of dihydroartemisinin-piperaquine after 10 years as treatment for vivax malaria in Indonesia.
Topics: Adult; Antimalarials; Child; Humans; Indonesia; Malaria; Malaria, Falciparum; Malaria, Vivax; Prospective Studies | 2023 |
Dihydroartemisinin Disrupts Zinc Homeostasis in
Topics: Animals; Antimalarials; Artemisinins; Folic Acid Antagonists; Glutathione; Homeostasis; Humans; Malaria; Malaria, Falciparum; Parasites; Plasmodium falciparum | 2023 |
Evolution of genetic markers for drug resistance after the introduction of dihydroartemisinin-piperaquine as first-line anti-malarial treatment for uncomplicated falciparum malaria in Indonesia.
Topics: Antimalarials; DNA Copy Number Variations; Drug Resistance; Genetic Markers; Humans; Indonesia; Malaria; Malaria, Falciparum; Plasmodium falciparum; Protozoan Proteins | 2023 |
Dihydroartemisinin-piperaquine efficacy in Plasmodium falciparum treatment and prevalence of drug-resistant molecular markers along China-Myanmar border in 2014-2023.
Topics: Antimalarials; China; Humans; Malaria, Falciparum; Myanmar; Plasmodium falciparum; Prevalence | 2023 |
Variation in neutrophil levels and artemisinin-based combination therapy efficacy in West-Africa.
Topics: Africa; Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Drug Combinations; Ethanolamines; Humans; Malaria; Malaria, Falciparum; Neutropenia; Neutrophils; Parasitemia; Plasmodium falciparum; Prospective Studies | 2023 |
Are k13 and plasmepsin II genes, involved in Plasmodium falciparum resistance to artemisinin derivatives and piperaquine in Southeast Asia, reliable to monitor resistance surveillance in Africa?
Topics: Africa; Antimalarials; Artemisinins; Aspartic Acid Endopeptidases; Drug Resistance; Humans; Malaria, Falciparum; Plasmodium falciparum; Protozoan Proteins; Quinolines | 2019 |
Suboptimal dosing triggers artemisinin partner drug resistance.
Topics: Artemisinins; Cambodia; Drug Resistance; Humans; Malaria, Falciparum; Prospective Studies; Quinolines; Thailand; Treatment Failure; Vietnam | 2019 |
Screen of traditional soup broths with reported antipyretic activity towards the discovery of potential antimalarials.
Topics: Antipyretics; Artemisinins; Child; Double-Blind Method; Drugs, Chinese Herbal; Food; Humans; Malaria, Falciparum; Meat; Medicine, Chinese Traditional; Plasmodium falciparum; Vegetables | 2019 |
Regulated rutin co-administration reverses mitochondrial-mediated apoptosis in Plasmodium berghei-infected mice.
Topics: Animals; Apoptosis; Artemisinins; Artesunate; Drug Therapy, Combination; Malaria, Falciparum; Male; Mefloquine; Mice; Mitochondria; Plasmodium berghei; Rutin | 2020 |
Gametocyte clearance in children, from western Kenya, with uncomplicated Plasmodium falciparum malaria after artemether-lumefantrine or dihydroartemisinin-piperaquine treatment.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Child, Preschool; Female; Humans; Infant; Kenya; Malaria, Falciparum; Male; Plasmodium falciparum; Prevalence; Quinolines | 2019 |
Artemether-Lumefantrine and Dihydroartemisinin-Piperaquine Retain High Efficacy for Treatment of Uncomplicated
Topics: Adolescent; Adult; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Drug Combinations; Female; Genotype; Humans; Malaria, Falciparum; Male; Middle Aged; Myanmar; Plasmodium falciparum; Quinolines; Young Adult | 2020 |
Efavirenz-Based Antiretroviral Therapy Reduces Artemether-Lumefantrine Exposure for Malaria Treatment in HIV-Infected Pregnant Women.
Topics: Adolescent; Adult; Alkynes; Anti-HIV Agents; Anti-Retroviral Agents; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Benzoxazines; Cyclopropanes; Drug Combinations; Drug Interactions; Female; HIV Infections; Humans; Lumefantrine; Malaria; Malaria, Falciparum; Pregnancy; Prospective Studies; Uganda; Young Adult | 2020 |
The extended recovery ring-stage survival assay provides a superior association with patient clearance half-life and increases throughput.
Topics: Antimalarials; Artemisinins; Benzothiazoles; Diamines; Drug Resistance; Erythrocytes; Flow Cytometry; Fluorescent Dyes; Half-Life; Humans; Malaria, Falciparum; Organic Chemicals; Parasitemia; Plasmodium falciparum; Povidone; Quinolines; Real-Time Polymerase Chain Reaction; Silicon Dioxide | 2020 |
Role of Plasmodium falciparum Kelch 13 Protein Mutations in P. falciparum Populations from Northeastern Myanmar in Mediating Artemisinin Resistance.
Topics: Antimalarials; Artemisinins; Asia, Southeastern; Drug Resistance; Humans; Malaria, Falciparum; Mutation; Organisms, Genetically Modified; Plasmodium falciparum; Protozoan Proteins | 2020 |
The Impact of Control Interventions on Malaria Burden in Young Children in a Historically High-Transmission District of Uganda: A Pooled Analysis of Cohort Studies from 2007 to 2018.
Topics: Antimalarials; Artemisinins; Child, Preschool; Cohort Studies; Communicable Disease Control; Directly Observed Therapy; Female; Housing; Humans; Infant; Insecticides; Malaria, Falciparum; Male; Mosquito Control; Organothiophosphorus Compounds; Quinolines; Trimethoprim, Sulfamethoxazole Drug Combination; Uganda | 2020 |
Efficacy of dihydroartemisinin/piperaquine and artesunate monotherapy for the treatment of uncomplicated Plasmodium falciparum malaria in Central Vietnam.
Topics: Antimalarials; Artemisinins; Artesunate; Humans; Malaria, Falciparum; Plasmodium falciparum; Quinolines; Vietnam | 2020 |
Ex-vivo Sensitivity of Plasmodium falciparum to Common Anti-malarial Drugs: The Case of Kéniéroba, a Malaria Endemic Village in Mali.
Topics: Adolescent; Amodiaquine; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Resistance; Endemic Diseases; Humans; Infant; Inhibitory Concentration 50; Lumefantrine; Malaria, Falciparum; Mali; Mefloquine; Plasmodium falciparum; Quinine; Quinolines | 2020 |
Recent Travel History and
Topics: Adolescent; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Therapy, Combination; Family Characteristics; Female; Humans; Malaria, Falciparum; Male; Mass Drug Administration; Plasmodium falciparum; Prevalence; Quinolines; Risk Factors; Travel; Zambia | 2020 |
Mass testing and treatment for malaria followed by weekly fever screening, testing and treatment in Northern Senegal: feasibility, cost and impact.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Child; Child, Preschool; Diagnostic Tests, Routine; Feasibility Studies; Female; Fever; Humans; Infant; Malaria, Falciparum; Male; Mass Screening; Middle Aged; Plasmodium falciparum; Quinolines; Senegal; Young Adult | 2020 |
Genetic screens reveal a central role for heme metabolism in artemisinin susceptibility.
Topics: Antimalarials; Artemisinins; Clustered Regularly Interspaced Short Palindromic Repeats; Drug Resistance; Gene Knockout Techniques; Genetic Testing; Heme; Humans; Malaria, Falciparum; Membrane Transport Proteins; Mutation; Plasmodium falciparum; Protozoan Proteins; Toxoplasma | 2020 |
Anti-malarial efficacy and resistance monitoring of artemether-lumefantrine and dihydroartemisinin-piperaquine shows inadequate efficacy in children in Burkina Faso, 2017-2018.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Burkina Faso; Child, Preschool; Drug Resistance; Female; Humans; Infant; Malaria, Falciparum; Male; Quinolines | 2021 |
Electrocardiographic effect of artemisinin-piperaquine, dihydroartemisinin-piperaquine, and artemether-lumefantrine treatment in falciparum malaria patients.
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Drug Combinations; Electrocardiography; Humans; Malaria; Malaria, Falciparum; Quinolines | 2021 |
Effect of Body Weight and Age on the Pharmacokinetics of Dihydroartemisinin: Food and Drug Administration Basis for Dose Determination of Artesunate for Injection in Pediatric Patients With Severe Malaria.
Topics: Antimalarials; Artemisinins; Artesunate; Body Weight; Child; Humans; Malaria; Malaria, Falciparum; United States; United States Food and Drug Administration | 2021 |
Unintentional artenimol/piperaquine overdose in two children occurring without evidence of subsequent cardiotoxicity.
Topics: Antimalarials; Artemisinins; Cardiotoxicity; Child; Child, Preschool; Drug Overdose; Drug Therapy, Combination; Humans; Malaria, Falciparum; Paris; Quinolines | 2021 |
Longitudinal study based on a safety registry for malaria patients treated with artenimol-piperaquine in six European countries.
Topics: Adolescent; Adult; Aged; Artemisinins; Belgium; Child; Child, Preschool; Communicable Diseases, Imported; Drug Combinations; Female; France; Germany; Humans; Italy; Longitudinal Studies; Malaria, Falciparum; Male; Middle Aged; Quinolines; Registries; Spain; United Kingdom; Young Adult | 2021 |
Restructured Mitochondrial-Nuclear Interaction in Plasmodium falciparum Dormancy and Persister Survival after Artemisinin Exposure.
Topics: Antimalarials; Artemisinins; Cell Nucleus; Erythrocytes; Humans; Malaria, Falciparum; Mitochondria; Plasmodium falciparum | 2021 |
Plasmodium falciparum phenotypic and genotypic resistance profile during the emergence of Piperaquine resistance in Northeastern Thailand.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; DNA Copy Number Variations; DNA, Protozoan; Drug Resistance; Drug Therapy, Combination; Endemic Diseases; Female; Genetic Association Studies; Genotype; Haplotypes; Humans; Malaria, Falciparum; Male; Middle Aged; Parasitemia; Plasmodium falciparum; Protozoan Proteins; Quinolines; Thailand; Young Adult | 2021 |
Efficacy of dihydroartemisinin/piperaquine in patients with non-complicated Plasmodium falciparum malaria in Yaoundé, Cameroon.
Topics: Antimalarials; Artemisinins; Cameroon; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum; Quinolines | 2021 |
Treatment Failure of Dihydroartemisinin/Piperaquine for Plasmodium falciparum Malaria, Vietnam.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Drug Combinations; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Mutation; Plasmodium falciparum; Protozoan Proteins; Quinolines; Vietnam | 2017 |
Post-licensure safety evaluation of dihydroartemisinin piperaquine in the three major ecological zones across Ghana.
Topics: Adolescent; Antimalarials; Artemisinins; Child; Child, Preschool; Drug-Related Side Effects and Adverse Reactions; Female; Ghana; Humans; Malaria, Falciparum; Male; Plasmodium falciparum; Quinolines | 2017 |
Topics: Antimalarials; Artemisinins; Cambodia; Cell Survival; Drug Resistance; Heterocyclic Compounds; Humans; Malaria, Falciparum; Mutation, Missense; Plasmodium falciparum; Protozoan Proteins; Virulence | 2017 |
A Variant PfCRT Isoform Can Contribute to
Topics: Antimalarials; Artemisinins; Cambodia; Drug Resistance; Gene Editing; Humans; Lethal Dose 50; Malaria, Falciparum; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Mutation; Plasmodium falciparum; Protein Isoforms; Protozoan Proteins; Quinolines | 2017 |
The Plasmodium PI(4)K inhibitor KDU691 selectively inhibits dihydroartemisinin-pretreated Plasmodium falciparum ring-stage parasites.
Topics: Animals; Antimalarials; Artemisinins; Cell Cycle Checkpoints; Drug Resistance; Humans; Malaria, Falciparum; Plasmodium falciparum; Pyrazines | 2017 |
Impact of Intermittent Preventive Treatment During Pregnancy on Plasmodium falciparum Drug Resistance-Mediating Polymorphisms in Uganda.
Topics: Antimalarials; Artemisinins; Drug Combinations; Drug Resistance; Female; Humans; Malaria, Falciparum; Plasmodium falciparum; Polymorphism, Genetic; Pregnancy; Pyrimethamine; Quinolines; Sulfadoxine | 2017 |
Sustained
Topics: Amodiaquine; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Drug Therapy, Combination; Ethanolamines; Fluorenes; Gambia; Humans; Lumefantrine; Malaria, Falciparum; Membrane Transport Proteins; Microsatellite Repeats; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Quinolines | 2017 |
The prevalence, incidence and prevention of Plasmodium falciparum infections in forest rangers in Bu Gia Map National Park, Binh Phuoc province, Vietnam: a pilot study.
Topics: Adult; Antibiotic Prophylaxis; Antimalarials; Artemisinins; Drug Therapy, Combination; Feasibility Studies; Humans; Incidence; Malaria, Falciparum; Male; Occupational Diseases; Parks, Recreational; Pilot Projects; Plasmodium falciparum; Prevalence; Primaquine; Quinolines; Vietnam | 2017 |
Researchers and WHO clash over global threat of drug resistant malaria.
Topics: Antimalarials; Artemisinins; Asia, Southeastern; Drug Resistance, Microbial; Humans; Malaria, Falciparum; Plasmodium falciparum; Quinolines; Research; Tropical Medicine; World Health Organization | 2017 |
Factors contributing to anaemia after uncomplicated falciparum malaria in under five year-old Nigerian children ten years following adoption of artemisinin-based combination therapies as first-line antimalarials.
Topics: Amodiaquine; Anemia; Antimalarials; Area Under Curve; Artemisinins; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Follow-Up Studies; Hematocrit; Humans; Infant; Kaplan-Meier Estimate; Logistic Models; Lumefantrine; Malaria, Falciparum; Male; Nigeria; Odds Ratio; Quinolines; ROC Curve; Treatment Outcome | 2017 |
Predicting Optimal Dihydroartemisinin-Piperaquine Regimens to Prevent Malaria During Pregnancy for Human Immunodeficiency Virus-Infected Women Receiving Efavirenz.
Topics: Adult; Alkynes; Anti-HIV Agents; Antimalarials; Artemisinins; Benzoxazines; Cyclopropanes; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; HIV Infections; Humans; Malaria, Falciparum; Pregnancy; Pregnancy Complications, Parasitic; Quinolines; Young Adult | 2018 |
Choreoathetosis - an unusual adverse effect of dihydroartemisinin-piperaquine: a case report.
Topics: Adult; Antimalarials; Artemisinins; Athetosis; Black People; Chorea; Drug Therapy, Combination; Humans; Malaria, Falciparum; Male; Quinolines; Treatment Outcome | 2017 |
Closing in on the Reservoir: Proactive Case Detection in High-Risk Groups as a Strategy to Detect Plasmodium falciparum Asymptomatic Carriers in Cambodia.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Cambodia; Carrier State; Child; Child, Preschool; Disease Reservoirs; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Pharmacy and Therapeutics Committee; Pilot Projects; Plasmodium falciparum; Primaquine; Quinolines; Risk Factors; Young Adult | 2018 |
Treatment for Uncomplicated Plasmodium falciparum Malaria in French Soldiers Deployed in Sub-Saharan Africa: Gaps Between Policy and Field Practice.
Topics: Adult; Antimalarials; Artemisinins; Atovaquone; Central African Republic; Drug Combinations; Female; France; Health Knowledge, Attitudes, Practice; Humans; Malaria, Falciparum; Male; Middle Aged; Physicians; Proguanil; Retrospective Studies; Surveys and Questionnaires | 2018 |
Efficacy and safety of artemether-lumefantrine, artesunate-amodiaquine, and dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium falciparum malaria in three provinces in Angola, 2017.
Topics: Adolescent; Amodiaquine; Angola; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Child, Preschool; Drug Combinations; Female; Humans; Infant; Malaria, Falciparum; Male; Parasitemia; Quinolines; Treatment Failure | 2018 |
Comparison of the Pharmacokinetics and Ex Vivo Antimalarial Activities of Artesunate-Amodiaquine and Artemisinin-Piperaquine in Healthy Volunteers for Preselection Malaria Therapy.
Topics: Amodiaquine; Antimalarials; Area Under Curve; Artemisinins; Biotransformation; Drug Administration Schedule; Drug Combinations; Half-Life; Healthy Volunteers; Humans; Malaria, Falciparum; Male; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Tablets; Young Adult | 2018 |
Longitudinal surveillance of drug resistance in Plasmodium falciparum isolates from the China-Myanmar border reveals persistent circulation of multidrug resistant parasites.
Topics: Antimalarials; Artemisinins; China; Chloroquine; Drug Resistance, Multiple; Epidemiological Monitoring; Genotype; Humans; In Vitro Techniques; Inhibitory Concentration 50; Lumefantrine; Malaria, Falciparum; Multidrug Resistance-Associated Proteins; Mutation; Myanmar; Plasmodium falciparum; Protozoan Proteins | 2018 |
Plasmodium falciparum Plasmepsin 2 Duplications, West Africa.
Topics: Antimalarials; Artemisinins; Aspartic Acid Endopeptidases; Drug Combinations; Drug Resistance; Humans; Malaria, Falciparum; Mali; Pilot Projects; Plasmodium falciparum; Quinolines | 2018 |
Efficacy of Artemisinin-Based Combination Treatments of Uncomplicated Falciparum Malaria in Under-Five-Year-Old Nigerian Children Ten Years Following Adoption as First-Line Antimalarials.
Topics: Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child, Preschool; Combined Modality Therapy; Drug Combinations; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Nigeria; Parasitemia; Plasmodium falciparum; Quinolines; Treatment Outcome | 2018 |
Dihydroartemisinin-piperaquine treatment failure in uncomplicated Plasmodium falciparum malaria case imported from Ethiopia.
Topics: Adult; Artemisinins; Communicable Diseases, Imported; Drug Combinations; Ethiopia; Female; Humans; Italy; Malaria, Falciparum; Quinolines; Treatment Failure | 2018 |
Population Pharmacokinetics of Artemether, Dihydroartemisinin, and Lumefantrine in Rwandese Pregnant Women Treated for Uncomplicated Plasmodium falciparum Malaria.
Topics: Adolescent; Adult; Antimalarials; Artemether; Artemisinins; Female; Humans; Lumefantrine; Malaria, Falciparum; Pregnancy; Tandem Mass Spectrometry; Young Adult | 2018 |
Investigating the Efficacy of Triple Artemisinin-Based Combination Therapies for Treating Plasmodium falciparum Malaria Patients Using Mathematical Modeling.
Topics: Antimalarials; Artemisinins; Asia, Southeastern; Drug Therapy, Combination; Humans; Malaria, Falciparum; Mefloquine; Models, Theoretical; Plasmodium falciparum; Quinolines | 2018 |
Gametocytes from K13 Propeller Mutant Plasmodium falciparum Clinical Isolates Demonstrate Reduced Susceptibility to Dihydroartemisinin in the Male Gamete Exflagellation Inhibition Assay.
Topics: Antimalarials; Artemisinins; Cambodia; Drug Resistance; Flagella; Germ Cells; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Mutation; Plasmodium falciparum; Protozoan Proteins | 2018 |
Topics: Antimalarials; Artemisinins; Artesunate; Computer Simulation; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Mefloquine; Models, Biological; Plasmodium falciparum; Quinolines; Treatment Failure | 2018 |
Electrocardiographic Safety of Repeated Monthly Dihydroartemisinin-Piperaquine as a Candidate for Mass Drug Administration.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Administration Schedule; Drug Combinations; Electrocardiography; Female; Healthy Volunteers; Humans; Long QT Syndrome; Malaria; Malaria, Falciparum; Malaria, Vivax; Male; Mass Drug Administration; Middle Aged; Papua New Guinea; Patient Safety; Prospective Studies; Quinolines | 2018 |
Cryptic severe
Topics: Administration, Intravenous; Administration, Oral; Antimalarials; Artemisinins; Artesunate; Humans; Italy; Malaria, Falciparum; Male; Middle Aged; Morocco; Plasmodium falciparum; Quinolines; Transients and Migrants; Treatment Outcome | 2018 |
Efficacy and safety of artemisinin-based combination therapy, and molecular markers for artemisinin and piperaquine resistance in Mainland Tanzania.
Topics: Adolescent; Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Child, Preschool; Drug Combinations; Female; Humans; Infant; Malaria, Falciparum; Male; Plasmodium falciparum; Prospective Studies; Quinolines; Tanzania | 2018 |
Dihydroartemisinin-Ferriprotoporphyrin IX Adduct Abundance in Plasmodium falciparum Malarial Parasites and the Relationship to Emerging Artemisinin Resistance.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Erythrocytes; Heme; Hemin; Humans; Malaria, Falciparum; Plasmodium falciparum | 2018 |
Has doxycycline, in combination with anti-malarial drugs, a role to play in intermittent preventive treatment of Plasmodium falciparum malaria infection in pregnant women in Africa?
Topics: Africa; Antimalarials; Artemisinins; Doxycycline; Drug Combinations; Female; Humans; Malaria, Falciparum; Pregnancy; Pregnancy Complications, Parasitic; Pregnant Women; Pyrimethamine; Quinolines; Sulfadoxine | 2018 |
Evaluation of the effects on the QT-interval of 4 artemisinin-based combination therapies with a correction-free and heart rate-free method.
Topics: Adolescent; Amodiaquine; Antimalarials; Arrhythmias, Cardiac; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Child, Preschool; Drug Combinations; Ethanolamines; Female; Fluorenes; Heart Rate; Humans; Long QT Syndrome; Malaria; Malaria, Falciparum; Male; Quinolines; Young Adult | 2019 |
Baseline
Topics: Animals; Antimalarials; Artemisinins; Aspartic Acid Endopeptidases; DNA Copy Number Variations; Humans; Malaria, Falciparum; Plasmodium falciparum; Protozoan Proteins; Quinolines; Senegal; Treatment Failure | 2019 |
Case Report: Hyperreactive Malarial Splenomegaly Syndrome Diagnosed with Loop-Mediated Isothermal Amplification and Treated with Artemisinin-Based Combination Therapy.
Topics: Adolescent; Antibodies, Protozoan; Antimalarials; Artemisinins; Belgium; Chronic Disease; Drug Therapy, Combination; Guinea; Humans; Malaria, Falciparum; Male; Nucleic Acid Amplification Techniques; Plasmodium falciparum; Quinolines; Splenomegaly; Temperature | 2019 |
High cure rates and tolerability of artesunate-amodiaquine and dihydroartemisinin-piperaquine for the treatment of uncomplicated falciparum malaria in Kibaha and Kigoma, Tanzania.
Topics: Amodiaquine; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Combinations; Female; Humans; Infant; Malaria, Falciparum; Male; Quinolines; Tanzania | 2019 |
Reduced Exposure to Piperaquine, Compared to Adults, in Young Children Receiving Dihydroartemisinin-Piperaquine as Malaria Chemoprevention.
Topics: Adult; Age Factors; Antimalarials; Artemisinins; Chemoprevention; Child, Preschool; Female; Humans; Infant; Malaria, Falciparum; Male; Quinolines; Young Adult | 2019 |
Decreased
Topics: Antimalarials; Artemisinins; Base Sequence; Drug Resistance; Erythrocytes; Gene Expression; Geography; Humans; India; Kelch Repeat; Life Cycle Stages; Malaria, Falciparum; Mutation; Plasmodium falciparum; Protozoan Proteins | 2019 |
Evolution and expansion of multidrug-resistant malaria in southeast Asia: a genomic epidemiology study.
Topics: Alleles; Antimalarials; Artemisinins; Asia, Southeastern; Drug Resistance, Multiple; Drug Therapy, Combination; Genome-Wide Association Study; Humans; Malaria, Falciparum; Membrane Transport Proteins; Mutation; Phylogeny; Phylogeography; Plasmodium falciparum; Protozoan Proteins; Quinolines; Whole Genome Sequencing | 2019 |
In vitro synergistic interaction of potent 4-aminoquinolines in combination with dihydroartemisinin against chloroquine-resistant Plasmodium falciparum.
Topics: Aminoquinolines; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Humans; Malaria, Falciparum; Plasmodium falciparum | 2019 |
Potential of artemisinin-based combination therapies to block malaria transmission.
Topics: Animals; Artemether, Lumefantrine Drug Combination; Artemisinins; Drug Combinations; Ethanolamines; Female; Fluorenes; Humans; Malaria, Falciparum; Male; Quinolines | 2013 |
Population pharmacokinetics of intramuscular artesunate in African children with severe malaria: implications for a practical dosing regimen.
Topics: Antimalarials; Artemisinins; Artesunate; Body Weight; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Infant; Injections, Intramuscular; Malaria, Falciparum; Models, Biological; Nonlinear Dynamics; Severity of Illness Index; Tanzania; Time Factors; Tissue Distribution | 2013 |
Ex vivo responses of Plasmodium falciparum clinical isolates to conventional and new antimalarial drugs in Niger.
Topics: Amodiaquine; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Naphthyridines; Niger; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines | 2013 |
Pharmacokinetic modelling of the anti-malarial drug artesunate and its active metabolite dihydroartemisinin.
Topics: Adult; Antimalarials; Artemisinins; Artesunate; Computer Simulation; Humans; Malaria, Falciparum; Mathematical Concepts; Models, Biological | 2013 |
Pharmacokinetic properties of artemether, dihydroartemisinin, lumefantrine, and quinine in pregnant women with uncomplicated plasmodium falciparum malaria in Uganda.
Topics: Adolescent; Adult; Artemether; Artemisinins; Ethanolamines; Female; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Pregnancy; Quinine; Young Adult | 2013 |
Ex vivo susceptibility of Plasmodium falciparum to antimalarial drugs in western, northern, and eastern Cambodia, 2011-2012: association with molecular markers.
Topics: Antimalarials; Artemisinins; Benzothiazoles; Biomarkers; Cambodia; Diamines; DNA Copy Number Variations; Drug Combinations; Drug Resistance, Multiple; Epidemiological Monitoring; Gene Expression; Humans; Malaria, Falciparum; Microscopy, Fluorescence; Multidrug Resistance-Associated Proteins; Organic Chemicals; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines | 2013 |
Tracking artemisinin resistance in Plasmodium falciparum.
Topics: Antimalarials; Artemisinins; Humans; Malaria, Falciparum; Plasmodium falciparum | 2013 |
Novel phenotypic assays for the detection of artemisinin-resistant Plasmodium falciparum malaria in Cambodia: in-vitro and ex-vivo drug-response studies.
Topics: Antimalarials; Artemisinins; Cambodia; Drug Resistance; Genotype; Humans; Malaria, Falciparum; Phenotype; Plasmodium falciparum; Prospective Studies; Survival Analysis; Survival Rate | 2013 |
Effects of body size and gender on the population pharmacokinetics of artesunate and its active metabolite dihydroartemisinin in pediatric malaria patients.
Topics: Administration, Oral; Adult; Age Factors; Antimalarials; Artemisinins; Artesunate; Body Size; Body Weight; Child; Child, Preschool; Computer Simulation; Drug Administration Schedule; Drug Dosage Calculations; Female; Half-Life; Humans; Malaria, Falciparum; Male; Microbial Sensitivity Tests; Models, Statistical; Plasmodium falciparum; Sex Factors | 2013 |
[Treatment of severe and uncomplicated falciparum malaria in children in France].
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Atovaquone; Child; Drug Combinations; Ethanolamines; Fluorenes; France; Humans; Malaria, Falciparum; Proguanil; Quinolines | 2013 |
Evidence for pyronaridine as a highly effective partner drug for treatment of artemisinin-resistant malaria in a rodent model.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Artesunate; Drug Combinations; Drug Resistance; Female; Flow Cytometry; Malaria, Falciparum; Mefloquine; Mice; Naphthyridines | 2014 |
Genome-wide screen identifies new candidate genes associated with artemisinin susceptibility in Plasmodium falciparum in Kenya.
Topics: Antimalarials; Artemisinins; Base Sequence; DNA, Protozoan; Drug Resistance; Genome, Protozoan; High-Throughput Nucleotide Sequencing; Humans; Kenya; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Single Nucleotide; Sequence Analysis, DNA | 2013 |
Dihydroartemisinin-piperaquine treatment of multidrug resistant falciparum and vivax malaria in pregnancy.
Topics: Acute Disease; Antimalarials; Artemisinins; Drug Resistance, Multiple; Female; Humans; Malaria, Falciparum; Malaria, Vivax; Parasitemia; Pregnancy; Pregnancy Complications, Parasitic; Pregnancy Outcome; Quinolines | 2014 |
Competition between Plasmodium falciparum strains in clinical infections during in vitro culture adaptation.
Topics: Alleles; Antigens, Protozoan; Antimalarials; Artemisinins; DNA, Protozoan; Drug Resistance; Genetic Variation; Genotype; Humans; Malaria, Falciparum; Merozoite Surface Protein 1; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Protozoan Proteins; Quinolines; Tetrahydrofolate Dehydrogenase | 2014 |
Inhibition of metalloproteinase-9 secretion and gene expression by artemisinin derivatives.
Topics: Artemisinins; Artesunate; Cytokines; Gene Expression Regulation; Humans; Inflammation Mediators; Malaria, Cerebral; Malaria, Falciparum; Matrix Metalloproteinase 9; Monocytes; Plasmodium falciparum; Polymerase Chain Reaction; RNA, Messenger | 2014 |
Role of Pfmdr1 in in vitro Plasmodium falciparum susceptibility to chloroquine, quinine, monodesethylamodiaquine, mefloquine, lumefantrine, and dihydroartemisinin.
Topics: Adult; Amodiaquine; Antimalarials; Artemisinins; Biological Transport; Child; Chloroquine; Drug Resistance; Erythrocytes; Ethanolamines; Female; Fluorenes; Gene Expression; Haplotypes; Humans; Inhibitory Concentration 50; Lumefantrine; Malaria, Falciparum; Male; Mefloquine; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Single Nucleotide; Quinine; Senegal | 2014 |
Effect of fluorescent dyes on in vitro-differentiated, late-stage Plasmodium falciparum gametocytes.
Topics: Antimalarials; Artemisinins; Artesunate; Carbocyanines; Erythrocytes; Fluorescent Dyes; Gametogenesis; Humans; Inhibitory Concentration 50; Life Cycle Stages; Luminescent Measurements; Malaria, Falciparum; Mitochondria; Plasmodium falciparum; Rhodamines | 2014 |
Efficacy of artemether-lumefantrine and dihydroartemisinin-piperaquine for treatment of uncomplicated malaria in children in Zaire and Uíge Provinces, angola.
Topics: Angola; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Drug Combinations; Drug Resistance; Ethanolamines; Female; Fluorenes; Humans; Malaria, Falciparum; Male; Plasmodium falciparum; Quinolines; Treatment Failure | 2015 |
In vivo selection of Plasmodium falciparum Pfcrt and Pfmdr1 variants by artemether-lumefantrine and dihydroartemisinin-piperaquine in Burkina Faso.
Topics: Antimanic Agents; Artemether, Lumefantrine Drug Combination; Artemisinins; Burkina Faso; Drug Combinations; Drug Resistance; Ethanolamines; Fluorenes; Genetic Variation; Humans; Malaria, Falciparum; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Protozoan Proteins; Quinolines | 2015 |
Contrasting benefits of different artemisinin combination therapies as first-line malaria treatments using model-based cost-effectiveness analysis.
Topics: Africa; Antimalarials; Artemisinins; Cost-Benefit Analysis; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Models, Theoretical; Quinolines; Seasons | 2014 |
In vivo monitoring of dihydroartemisinin-piperaquine sensitivity in Plasmodium falciparum along the China-Myanmar border of Yunnan Province, China from 2007 to 2013.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Child, Preschool; China; Drug Resistance; Female; Humans; Kaplan-Meier Estimate; Malaria, Falciparum; Male; Middle Aged; Myanmar; Parasitemia; Plasmodium falciparum; Public Health Surveillance; Quinolines; Young Adult | 2015 |
Polymorphisms of the Pfatpase 6 and Pfcrt gene and their relationship with the in vitro susceptibility to dihydroartemisinin and chloroquine of Plasmodium falciparum isolates from Abobo, Côte d'Ivoire.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Cote d'Ivoire; Drug Resistance; Gene Expression Regulation; Humans; Malaria, Falciparum; Membrane Transport Proteins; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Sarcoplasmic Reticulum Calcium-Transporting ATPases | 2014 |
[Therapeutic effect of 138 imported falciparum malaria patients].
Topics: Adult; Africa; Antimalarials; Artemether; Artemisinins; Artesunate; China; Diagnostic Errors; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Retrospective Studies; Travel; Young Adult | 2014 |
A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria.
Topics: Antimalarials; Artemisinins; Drug Resistance; Genome-Wide Association Study; Malaria, Falciparum; Models, Molecular; Mutation; Phosphatidylinositol 3-Kinase; Phosphatidylinositol Phosphates; Phosphoinositide-3 Kinase Inhibitors; Plasmodium falciparum; Protozoan Proteins | 2015 |
Dihydroartemisinin-piperaquine failure associated with a triple mutant including kelch13 C580Y in Cambodia: an observational cohort study.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Cambodia; Cohort Studies; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Mutation, Missense; Plasmodium falciparum; Point Mutation; Protozoan Proteins; Quinolines; Randomized Controlled Trials as Topic; Treatment Failure; Young Adult | 2015 |
Mass campaigns with antimalarial drugs: a modelling comparison of artemether-lumefantrine and DHA-piperaquine with and without primaquine as tools for malaria control and elimination.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Infant; Malaria, Falciparum; Male; Middle Aged; Models, Biological; Post-Exposure Prophylaxis; Prevalence; Primaquine; Quinolines; Young Adult; Zambia | 2015 |
Population pharmacokinetics, tolerability, and safety of dihydroartemisinin-piperaquine and sulfadoxine-pyrimethamine-piperaquine in pregnant and nonpregnant Papua New Guinean women.
Topics: Adolescent; Adult; Antimalarials; Area Under Curve; Artemisinins; Biological Availability; Dietary Fats; Drug Combinations; Female; Follow-Up Studies; Food-Drug Interactions; Humans; Infant, Newborn; Malaria, Falciparum; Models, Statistical; Papua New Guinea; Pregnancy; Pregnancy Outcome; Pyrimethamine; Quinolines; Sulfadoxine; Young Adult | 2015 |
Ex Vivo Drug Susceptibility Testing and Molecular Profiling of Clinical Plasmodium falciparum Isolates from Cambodia from 2008 to 2013 Suggest Emerging Piperaquine Resistance.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Cambodia; Chloroquine; Drug Resistance; Female; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Male; Mefloquine; Membrane Transport Proteins; Middle Aged; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Young Adult | 2015 |
Lack of Artemisinin Resistance in Plasmodium falciparum in Uganda Based on Parasitological and Molecular Assays.
Topics: Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria, Falciparum; Molecular Sequence Data; Parasitemia; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Uganda | 2015 |
Measuring windows of selection for anti-malarial drug treatments.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Drug Combinations; Ethanolamines; Fluorenes; Humans; Malaria, Falciparum; Models, Biological; Plasmodium falciparum; Quinolines | 2015 |
How Robust Are Malaria Parasite Clearance Rates as Indicators of Drug Effectiveness and Resistance?
Topics: Adult; Antimalarials; Artemisinins; Artesunate; Child; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Drug Dosage Calculations; Drug Resistance; Humans; Immunity, Innate; Malaria, Falciparum; Mefloquine; Models, Statistical; Parasitemia; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Treatment Outcome | 2015 |
An Economic Evaluation of the Posttreatment Prophylactic Effect of Dihydroartemisinin-Piperaquine Versus Artemether-Lumefantrine for First-Line Treatment of Plasmodium falciparum Malaria Across Different Transmission Settings in Africa.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Drug Combinations; Ethanolamines; Fluorenes; Humans; Malaria, Falciparum; Markov Chains; Models, Biological; Models, Economic; Plasmodium falciparum; Quinolines; Recurrence | 2015 |
High Antimalarial Efficacy of Dihydroartemisinin-Piperaquine on the China-Myanmar Border: The Calm Before the Storm.
Topics: Antimalarials; Artemisinins; China; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Myanmar; Plasmodium falciparum; Quinolines; Treatment Outcome | 2015 |
Artemisinin resistance at the China-Myanmar border and association with mutations in the K13 propeller gene.
Topics: Artemisinins; China; Drug Resistance, Multiple; Genotype; Malaria, Falciparum; Mutation; Myanmar; Plasmodium falciparum; Quinolines | 2015 |
Artemether-Lumefantrine Exposure in HIV-Infected Nigerian Subjects on Nevirapine-Containing Antiretroviral Therapy.
Topics: Adult; Anti-HIV Agents; Antimalarials; Artemether; Artemisinins; Case-Control Studies; Coinfection; Drug Combinations; Drug Interactions; Ethanolamines; Female; Fluorenes; HIV Infections; HIV-1; Humans; Lumefantrine; Malaria, Falciparum; Male; Nevirapine; Nigeria; Plasmodium falciparum | 2015 |
Optimum population-level use of artemisinin combination therapies: a modelling study.
Topics: Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Drug Administration Schedule; Drug Combinations; Drug Resistance; Ethanolamines; Fluorenes; Humans; Malaria, Falciparum; Models, Biological; Plasmodium falciparum; Quinolines; Treatment Failure | 2015 |
Plasmodium falciparum dihydroartemisinin-piperaquine failures in Cambodia are associated with mutant K13 parasites presenting high survival rates in novel piperaquine in vitro assays: retrospective and prospective investigations.
Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Cambodia; Female; Humans; Malaria, Falciparum; Male; Parasites; Plasmodium falciparum; Prospective Studies; Quinolines; Retrospective Studies; Survival Rate; Treatment Failure; Treatment Outcome; Young Adult | 2015 |
Atovaquone-Proguanil Remains a Potential Stopgap Therapy for Multidrug-Resistant Plasmodium falciparum in Areas along the Thai-Cambodian Border.
Topics: Antimalarials; Artemisinins; Atovaquone; Base Sequence; Cambodia; DNA, Protozoan; Drug Combinations; Drug Resistance, Multiple; Humans; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum; Proguanil; Quinolines; Sequence Analysis, DNA; Thailand | 2015 |
Dihydroartemisinin-piperaquine resistance in Plasmodium falciparum malaria in Cambodia: a multisite prospective cohort study.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Cambodia; Child; Child, Preschool; Cohort Studies; Drug Resistance; Drug Therapy, Combination; Female; Genotype; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Prospective Studies; Quinolines; Young Adult | 2016 |
Safety of artemisinins in first trimester of prospectively followed pregnancies: an observational study.
Topics: Abortion, Spontaneous; Adolescent; Adult; Antimalarials; Artemisinins; Female; Humans; Malaria, Falciparum; Malaria, Vivax; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Quinine; Thailand | 2016 |
UK malaria treatment guidelines 2016.
Topics: Adult; Antimalarials; Artemisinins; Artesunate; Breast Feeding; Child; Child, Preschool; Female; Humans; Malaria; Malaria, Falciparum; Malaria, Vivax; Plasmodium falciparum; Plasmodium vivax; Pregnancy; Pregnancy Complications, Parasitic; Primaquine; Travel | 2016 |
Parasite clearance rates in Upper Myanmar indicate a distinctive artemisinin resistance phenotype: a therapeutic efficacy study.
Topics: Administration, Oral; Adolescent; Adult; Aged; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Resistance; Female; Humans; Infant; Malaria, Falciparum; Male; Middle Aged; Mutation, Missense; Myanmar; Parasitemia; Prospective Studies; Protozoan Proteins; Quinolines; Young Adult | 2016 |
[Multiple and successive treatment failures in a patient infected by Plasmodium falciparum in Cambodia and treated by dihydroartemisinin-piperaquine].
Topics: Antimalarials; Artemisinins; Cambodia; Drug Therapy, Combination; Humans; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Quinolines; Recurrence; Treatment Failure | 2016 |
Highly active ozonides selected against drug resistant malaria.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Disease Models, Animal; Female; Humans; Malaria, Falciparum; Mefloquine; Mice; Parasitemia; Plasmodium falciparum | 2016 |
Hemolysis after Oral Artemisinin Combination Therapy for Uncomplicated Plasmodium falciparum Malaria.
Topics: Administration, Oral; Adolescent; Adult; Anemia; Antimalarials; Artemether; Artemisinins; Child; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Hemolysis; Humans; Lumefantrine; Malaria, Falciparum; Male; Prospective Studies; Quinolines | 2016 |
Assessing the asymptomatic reservoir and dihydroartemisinin-piperaquine effectiveness in a low transmission setting threatened by artemisinin resistant Plasmodium falciparum.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Asymptomatic Diseases; Cambodia; Child; Child, Preschool; Cross-Sectional Studies; Drug Resistance; Female; Humans; Incidence; Infant; Infant, Newborn; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Prevalence; Quinolines; Real-Time Polymerase Chain Reaction; Treatment Outcome; Young Adult | 2016 |
Failure of dihydroartemisinin plus piperaquine treatment of falciparum malaria by under-dosing in an overweight patient.
Topics: Adult; Antimalarials; Artemisinins; Djibouti; Drug Therapy, Combination; France; Humans; Malaria, Falciparum; Male; Military Personnel; Overweight; Quinolines; Treatment Failure | 2016 |
Failure of dihydroartemisinin-piperaquine treatment of uncomplicated Plasmodium falciparum malaria in a traveller coming from Ethiopia.
Topics: Adult; Antimalarials; Artemisinins; Ethiopia; France; Humans; Malaria, Falciparum; Military Personnel; Overweight; Quinolines; Treatment Failure | 2016 |
A surrogate marker of piperaquine-resistant Plasmodium falciparum malaria: a phenotype-genotype association study.
Topics: Antimalarials; Artemisinins; Aspartic Acid Endopeptidases; Biomarkers; Cambodia; DNA Copy Number Variations; Drug Resistance, Multiple; Genetic Association Studies; Humans; Malaria, Falciparum; Plasmodium falciparum; Quinolines; Treatment Failure | 2017 |
Treatment-seeking behaviour and associated costs for malaria in Papua, Indonesia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Child; Child, Preschool; Cost of Illness; Cross-Sectional Studies; Family Characteristics; Female; Guideline Adherence; Health Expenditures; Humans; Indonesia; Infant; Infant, Newborn; Malaria, Falciparum; Malaria, Vivax; Male; Middle Aged; Patient Acceptance of Health Care; Quinolines; Random Allocation; Young Adult | 2016 |
Dihydroartemisinin-piperaquine: if it works for control, can we use it for elimination?
Topics: Antimalarials; Artemisinins; Malaria, Falciparum; Quinolines | 2017 |
Insight into k13-propeller gene polymorphism and ex vivo DHA-response profiles from Cameroonian isolates.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Cameroon; Child; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Parasitic Sensitivity Tests; Plasmodium falciparum; Point Mutation; Polymorphism, Genetic; Prospective Studies; Protozoan Proteins; Quinolines; Treatment Outcome; Volunteers; Young Adult | 2016 |
Association between Polymorphisms in the Pf
Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Asparagine; ATP-Binding Cassette Transporters; Chloroquine; Doxycycline; Drug Resistance; Ethanolamines; Fluorenes; Gene Expression; Humans; Inhibitory Concentration 50; Lumefantrine; Malaria, Falciparum; Mefloquine; Naphthyridines; Plasmodium falciparum; Polymorphism, Genetic; Protein Isoforms; Protozoan Proteins; Quinine; Quinolines; Repetitive Sequences, Amino Acid; Senegal | 2017 |
Rapid decline in the susceptibility of Plasmodium falciparum to dihydroartemisinin-piperaquine in the south of Vietnam.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Resistance; Endemic Diseases; Female; Humans; Incidence; Malaria, Falciparum; Male; Plasmodium falciparum; Quinolines; Time Factors; Treatment Failure; Vietnam; Young Adult | 2017 |
Efficacy of artemether-lumefantrine, artesunate-amodiaquine, and dihydroartemisinin-piperaquine for treatment of uncomplicated Plasmodium falciparum malaria in Angola, 2015.
Topics: Amodiaquine; Angola; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Child, Preschool; Drug Combinations; Ethanolamines; Female; Fluorenes; Humans; Infant; Malaria, Falciparum; Male; Quinolines; Recurrence; Treatment Failure | 2017 |
Emergence of Indigenous Artemisinin-Resistant Plasmodium falciparum in Africa.
Topics: Adult; Africa; Antimalarials; Artemisinins; Asia, Southeastern; Drug Resistance; Drug Therapy, Combination; Equatorial Guinea; Humans; Malaria, Falciparum; Male; Mutation; Papua New Guinea; Parasitemia; Plasmodium falciparum; Polymorphism, Single Nucleotide; Quinolines | 2017 |
Prediction of Improved Antimalarial Chemoprevention with Weekly Dosing of Dihydroartemisinin-Piperaquine.
Topics: Antimalarials; Artemisinins; Chemoprevention; Computer Simulation; Drug Administration Schedule; Drug Therapy, Combination; Humans; Malaria, Falciparum; Quinolines; Treatment Outcome | 2017 |
Major pitfalls in the measurement of artemisinin derivatives in plasma in clinical studies.
Topics: Anticoagulants; Antimalarials; Artemisinins; Female; Hemolysis; Humans; Malaria, Falciparum; Pregnancy; Pregnancy Complications, Infectious; Solid Phase Extraction; Tandem Mass Spectrometry; Temperature | 2008 |
Molecular epidemiology of malaria in Cameroon. XXVIII. In vitro activity of dihydroartemisinin against clinical isolates of Plasmodium falciparum and sequence analysis of the P. falciparum ATPase 6 gene.
Topics: Animals; Antimalarials; Artemisinins; Calcium-Transporting ATPases; Cameroon; Haplotypes; Humans; Malaria, Falciparum; Mutation; Plasmodium falciparum | 2009 |
Dihydroartemisinin pharmacokinetics in patients with malaria after multiple doses--assembling clues and perspectives.
Topics: Artemisinins; Humans; Malaria, Falciparum | 2009 |
Safety and efficacy of dihydroartemisinin-piperaquine in falciparum malaria: a prospective multi-centre individual patient data analysis.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Child; Child, Preschool; Female; Humans; Infant; Malaria, Falciparum; Male; Middle Aged; Prospective Studies; Quinolines; Randomized Controlled Trials as Topic | 2009 |
Artemisinin combination therapy for malaria: beyond good efficacy.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child, Preschool; Drug Combinations; Ethanolamines; Fluorenes; Humans; Infant; Malaria, Falciparum; Quinolines; Treatment Outcome | 2009 |
Selection of known Plasmodium falciparum resistance-mediating polymorphisms by artemether-lumefantrine and amodiaquine-sulfadoxine-pyrimethamine but not dihydroartemisinin-piperaquine in Burkina Faso.
Topics: Amodiaquine; Antimalarials; Artemether; Artemisinins; Burkina Faso; Drug Combinations; Drug Resistance, Bacterial; Ethanolamines; Fluorenes; Genotype; Humans; Infant; Lumefantrine; Malaria, Falciparum; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Pyrimethamine; Quinolines; Randomized Controlled Trials as Topic; Recurrence; Sulfadoxine | 2010 |
Comparison of plasma, venous and capillary blood levels of piperaquine in patients with uncomplicated falciparum malaria.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Blood Chemical Analysis; Capillaries; Child; Child, Preschool; Drug Combinations; Female; Fingers; Humans; Malaria, Falciparum; Male; Middle Aged; Phlebotomy; Plasma; Quinolines; Randomized Controlled Trials as Topic | 2010 |
Severe congenital malaria acquired in utero.
Topics: Adult; Antimalarials; Artemisinins; Artesunate; Female; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Malaria, Falciparum; Pregnancy; Quinolines | 2010 |
A liquid chromatographic-tandem mass spectrometric method for determination of artemether and its metabolite dihydroartemisinin in human plasma.
Topics: Antimalarials; Artemether; Artemisinins; Calibration; Chromatography, Liquid; Drug Therapy, Combination; Ethanolamines; Fluorenes; High-Throughput Screening Assays; Humans; Lumefantrine; Malaria, Falciparum; Reproducibility of Results; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2009 |
Pharmacokinetics and pharmacodynamics of artesunate and dihydroartemisinin following oral treatment in pregnant women with asymptomatic Plasmodium falciparum infections in Kinshasa DRC.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Asymptomatic Infections; Chromatography, Liquid; Democratic Republic of the Congo; Female; Humans; Infant, Newborn; Malaria, Falciparum; Mass Spectrometry; Plasma; Plasmodium falciparum; Pregnancy; Pregnancy Complications, Infectious; Young Adult | 2011 |
Piperaquine resistance is associated with a copy number variation on chromosome 5 in drug-pressured Plasmodium falciparum parasites.
Topics: Antimalarials; Artemisinins; DNA Copy Number Variations; Drug Resistance; Drug Therapy, Combination; Genome, Protozoan; Malaria, Falciparum; Phenotype; Plasmodium falciparum; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Quinolines | 2011 |
Novel polymorphisms in Plasmodium falciparum ABC transporter genes are associated with major ACT antimalarial drug resistance.
Topics: Animals; Antimalarials; Artemisinins; ATP-Binding Cassette Transporters; Base Sequence; Drug Resistance; Ethanolamines; Fluorenes; Gene Frequency; Genotype; Haplotypes; Humans; Inhibitory Concentration 50; Lumefantrine; Malaria, Falciparum; Mefloquine; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins | 2011 |
Artemisinin activity against Plasmodium falciparum requires hemoglobin uptake and digestion.
Topics: Animals; Antimalarials; Artemisinins; Biological Transport, Active; Cysteine Endopeptidases; Endocytosis; Erythrocytes; Gene Deletion; Genes, Protozoan; Hemoglobins; Host-Parasite Interactions; Humans; Malaria, Falciparum; Parasitemia; Plasmodium falciparum | 2011 |
Meningeal inflammation increases artemether concentrations in cerebrospinal fluid in Papua New Guinean children treated with intramuscular artemether.
Topics: Artemether; Artemisinins; Child; Child, Preschool; Female; Humans; Infant; Injections, Intramuscular; Malaria, Falciparum; Male; Meninges; Papua New Guinea; Prospective Studies | 2011 |
Indolone-N-oxide derivatives: in vitro activity against fresh clinical isolates of Plasmodium falciparum, stage specificity and in vitro interactions with established antimalarial drugs.
Topics: Adult; Antimalarials; Artemisinins; Cameroon; Chloroquine; Drug Interactions; Drug Resistance; Female; Humans; Hypoxanthine; Indoles; Malaria, Falciparum; Male; Nitrogen Oxides; Oxidation-Reduction; Parasitic Sensitivity Tests; Plasmodium falciparum | 2011 |
Highly effective therapy for maternal malaria associated with a lower risk of vertical transmission.
Topics: Antimalarials; Artemisinins; Drug Combinations; Female; Humans; Indonesia; Infant, Newborn; Infectious Disease Transmission, Vertical; Malaria, Falciparum; Malaria, Vivax; Population Surveillance; Pregnancy; Prospective Studies; Quinolines; Risk Factors | 2011 |
Pharmacokinetics of dihydroartemisinin and piperaquine in pregnant and nonpregnant women with uncomplicated falciparum malaria.
Topics: Adult; Antimalarials; Area Under Curve; Artemisinins; Drug Administration Schedule; Drug Therapy, Combination; Female; Half-Life; Humans; Malaria, Falciparum; Pregnancy; Pregnancy Complications, Parasitic; Pregnancy Outcome; Quinolines; Thailand; Young Adult | 2011 |
Artesunate/dihydroartemisinin pharmacokinetics in acute falciparum malaria in pregnancy: absorption, bioavailability, disposition and disease effects.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Biological Availability; Dose-Response Relationship, Drug; Female; Humans; Malaria, Falciparum; Metabolic Clearance Rate; Postpartum Period; Pregnancy; Pregnancy Complications, Parasitic; Severity of Illness Index; Young Adult | 2012 |
Population pharmacokinetics of Artemether and dihydroartemisinin in pregnant women with uncomplicated Plasmodium falciparum malaria in Uganda.
Topics: Administration, Oral; Adolescent; Adult; Antimalarials; Artemether; Artemisinins; Chromatography; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Mass Spectrometry; Models, Statistical; Plasma; Pregnancy; Pregnancy Complications, Infectious; Uganda; Young Adult | 2012 |
Assessing the utility of an anti-malarial pharmacokinetic-pharmacodynamic model for aiding drug clinical development.
Topics: Animals; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Dose-Response Relationship, Drug; Drug Combinations; Drug Discovery; Ethanolamines; Fluorenes; Host-Pathogen Interactions; Humans; Malaria, Falciparum; Mefloquine; Models, Statistical; Plasmodium falciparum; Quinolines | 2012 |
Optimizing the HRP-2 in vitro malaria drug susceptibility assay using a reference clone to improve comparisons of Plasmodium falciparum field isolates.
Topics: Antigens, Protozoan; Antimalarials; Artemisinins; Artesunate; Chromatography, Liquid; Culture Media; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Mass Spectrometry; Parasitic Sensitivity Tests; Plasmodium falciparum; Protozoan Proteins | 2012 |
A population pharmacokinetic model of piperaquine in pregnant and non-pregnant women with uncomplicated Plasmodium falciparum malaria in Sudan.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Biological Availability; Drug Combinations; Female; Humans; Malaria, Falciparum; Metabolic Clearance Rate; Models, Biological; Nonlinear Dynamics; Pregnancy; Pregnancy Complications, Parasitic; Quinolines; Sudan; Young Adult | 2012 |
Reduced artemisinin susceptibility of Plasmodium falciparum ring stages in western Cambodia.
Topics: Antimalarials; Artemisinins; Cambodia; Cell Cycle Checkpoints; Drug Resistance; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum | 2013 |
Efficacy of dihydroartemisinin-piperaquine for treatment of uncomplicated Plasmodium falciparum and Plasmodium vivax in Cambodia, 2008 to 2010.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Cambodia; Child; Chloroquine; Drug Resistance; Drug Therapy, Combination; Female; Genotype; Humans; Malaria, Falciparum; Malaria, Vivax; Male; Mefloquine; Membrane Transport Proteins; Middle Aged; Parasitic Sensitivity Tests; Plasmodium falciparum; Plasmodium vivax; Protozoan Proteins; Quinolines; Treatment Outcome; Young Adult | 2013 |
Synthesis of a potent antimalarial agent through natural products conjugation.
Topics: Animals; Antimalarials; Artemisinins; Benzofurans; Biological Products; Cell Line; Drug Discovery; Female; Malaria, Falciparum; Mice; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats | 2013 |
Glucuronidation of dihydroartemisinin in vivo and by human liver microsomes and expressed UDP-glucuronosyltransferases.
Topics: Adult; Antimalarials; Artemisinins; Artesunate; Female; Glucuronides; Glucuronosyltransferase; Humans; In Vitro Techniques; Malaria, Falciparum; Male; Microsomes, Liver; Recombinant Proteins; Sesquiterpenes | 2002 |
[Therapeutic effect of dihydroartemisinin combined with naphthoquine phosphate in patients with falciparum malaria].
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Malaria, Falciparum; Male; Middle Aged; Sesquiterpenes; Treatment Outcome | 2002 |
Comparison of bioassay and high performance liquid chromatographic assay of artesunate and dihydroartemisinin in plasma.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Biological Assay; Chromatography, High Pressure Liquid; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Plasmodium falciparum; Sesquiterpenes | 2003 |
In vitro activity and interaction of clindamycin combined with dihydroartemisinin against Plasmodium falciparum.
Topics: Animals; Anti-Bacterial Agents; Antimalarials; Artemisinins; Clindamycin; Drug Combinations; Drug Resistance; Drug Synergism; Humans; Malaria, Falciparum; Plasmodium falciparum; Sesquiterpenes | 2003 |
Population pharmacokinetics of artemether and dihydroartemisinin following single intramuscular dosing of artemether in African children with severe falciparum malaria.
Topics: Acidosis, Respiratory; Antimalarials; Artemether; Artemisinins; Child; Child, Preschool; Female; Half-Life; Humans; Infant; Injections, Intramuscular; Malaria, Falciparum; Male; Respiratory Insufficiency; Sesquiterpenes | 2004 |
Plasmodium falciparum-based bioassay for measurement of artemisinin derivatives in plasma or serum.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Biological Assay; Biotransformation; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Electrochemistry; Hot Temperature; Humans; In Vitro Techniques; Macaca mulatta; Malaria, Falciparum; Plasmodium falciparum; Reproducibility of Results; Sesquiterpenes | 2004 |
Protein binding and alpha : beta anomer ratio of dihydroartemisinin in vivo.
Topics: Adult; Albumins; Antimalarials; Artemisinins; Female; Humans; Malaria, Falciparum; Male; Protein Binding; Sesquiterpenes | 2004 |
[Effects of combined artemether and dihydroarteamisinin in treatment of children with falciparum malaria].
Topics: Antimalarials; Artemether; Artemisinins; Child; Drug Therapy, Combination; Humans; Malaria, Falciparum | 2005 |
Once-daily combination therapy for uncomplicated malaria: is this the way forward?
Topics: Animals; Antimalarials; Artemisinins; Drug Combinations; Drug Resistance, Multiple; Humans; Malaria, Falciparum; Plasmodium falciparum; Quinolines; Sesquiterpenes | 2005 |
In vitro antimalarial drug susceptibility in Thai border areas from 1998-2003.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Quinine; Sesquiterpenes; Thailand; Time Factors | 2005 |
In-vitro susceptibility of Plasmodium falciparum to monodesethylamodiaquine, dihydroartemisinin and quinine in an area of high chloroquine resistance in Rwanda.
Topics: Adolescent; Adult; Amodiaquine; Animals; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Resistance, Multiple; Female; Humans; Infant; Inhibitory Concentration 50; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Quinine; Rwanda; Sesquiterpenes | 2006 |
Pharmacokinetics of dihydroartemisinin following oral artesunate treatment of pregnant women with acute uncomplicated falciparum malaria.
Topics: Acute Disease; Adolescent; Adult; Analysis of Variance; Antimalarials; Artemisinins; Artesunate; Atovaquone; Drug Combinations; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Half-Life; Humans; Malaria, Falciparum; Pregnancy; Pregnancy Complications, Parasitic; Pregnancy Outcome; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Proguanil; Sesquiterpenes; Thailand | 2006 |
Artemisinin combination therapies.
Topics: Adult; Africa; Antimalarials; Artemisinins; Artesunate; Asia; Child, Preschool; Drug Therapy, Combination; Humans; Malaria, Falciparum; Mefloquine; Quinolines; Sesquiterpenes | 2006 |
Quality control of active ingredients in artemisinin-derivative antimalarials within Kenya and DR Congo.
Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Capsules; Chromatography, High Pressure Liquid; Democratic Republic of the Congo; Dosage Forms; Endemic Diseases; Humans; Kenya; Malaria, Falciparum; Quality Control; Sesquiterpenes; Tablets | 2007 |
In vitro antimalarial drug susceptibility and pfcrt mutation among fresh Plasmodium falciparum isolates from the Lao PDR (Laos).
Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; DNA, Protozoan; Drug Resistance; Ethanolamines; Female; Fluorenes; Humans; Inhibitory Concentration 50; Laos; Lumefantrine; Malaria, Falciparum; Male; Mefloquine; Membrane Transport Proteins; Middle Aged; Plasmodium falciparum; Point Mutation; Polymerase Chain Reaction; Protozoan Proteins; Sesquiterpenes | 2007 |
In vitro interaction of dihydroartemisin and lumefantrine in clinical field isolates from Bangladesh.
Topics: Animals; Antimalarials; Artemisinins; Bangladesh; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Lethal Dose 50; Lumefantrine; Malaria, Falciparum; Plasmodium falciparum; Survival Rate; Treatment Outcome | 2007 |
[In vitro interaction studies of azithromycin and dihydroartemisinin in Plasmodium falciparum isolates from Bangladesh].
Topics: Animals; Artemisinins; Azithromycin; Bangladesh; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Humans; Lethal Dose 50; Malaria, Falciparum; Plasmodium falciparum; Survival Rate; Treatment Outcome | 2007 |
Assessment of in vitro antimalarial interactions between dihydroartemisinin and fosmidomycin.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance; Fosfomycin; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Plasmodium falciparum; Schizonts; Sesquiterpenes | 2007 |
Dihydroartemisinin-piperaquine rescue treatment of multidrug-resistant Plasmodium falciparum malaria in pregnancy: a preliminary report.
Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Drug Therapy, Combination; Female; Fever; Gestational Age; Gravidity; Humans; Malaria, Falciparum; Parity; Plasmodium falciparum; Plasmodium vivax; Pregnancy; Pregnancy Complications, Infectious; Quinolines; Retrospective Studies; Thailand | 2008 |
Adverse pregnancy outcomes in an area where multidrug-resistant plasmodium vivax and Plasmodium falciparum infections are endemic.
Topics: Adult; Animals; Antimalarials; Artemisinins; Cross-Sectional Studies; Drug Resistance, Multiple; Endemic Diseases; Female; Humans; Indonesia; Malaria, Falciparum; Malaria, Vivax; Parasitemia; Plasmodium falciparum; Plasmodium vivax; Pregnancy; Pregnancy Complications, Parasitic; Pregnancy Outcome; Quinolines; Surveys and Questionnaires | 2008 |
Clinical trials of artemisinin and its derivatives in the treatment of malaria in China.
Topics: Antimalarials; Antiprotozoal Agents; Artemisinins; Artesunate; China; Clinical Trials as Topic; Humans; Injections, Intramuscular; Injections, Intravenous; Malaria, Cerebral; Malaria, Falciparum; Sesquiterpenes; Suppositories; Tablets | 1994 |
Pharmacokinetics of artemether after oral administration to healthy Thai males and patients with acute, uncomplicated falciparum malaria.
Topics: Administration, Oral; Adult; Animals; Antimalarials; Artemether; Artemisinins; Humans; Malaria, Falciparum; Male; Plasmodium falciparum; Sesquiterpenes; Thailand | 1994 |
Selective high-performance liquid chromatographic determination of artesunate and alpha- and beta-dihydroartemisinin in patients with falciparum malaria.
Topics: Antimalarials; Artemisinins; Artesunate; Chromatography, High Pressure Liquid; Humans; Isomerism; Malaria, Falciparum; Reproducibility of Results; Sesquiterpenes; Spectrophotometry, Ultraviolet | 1996 |
Treatment of acute, uncomplicated, falciparum malaria with oral dihydroartemisinin.
Topics: Acute Disease; Adolescent; Adult; Antimalarials; Artemisinins; Drug Resistance, Multiple; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Parasitemia; Sesquiterpenes; Thailand; Treatment Outcome | 1996 |
In vitro stage-specific sensitivity of Plasmodium falciparum to quinine and artemisinin drugs.
Topics: Adult; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Drug Evaluation, Preclinical; Drug Resistance; Humans; In Vitro Techniques; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Quinine; Sesquiterpenes | 1996 |
Pharmacokinetic and bioequivalence evaluation of two generic formulations of oral artesunate.
Topics: Administration, Oral; Adult; Animals; Antimalarials; Artemisinins; Artesunate; Drugs, Generic; Humans; Malaria, Falciparum; Male; Plasmodium falciparum; Sesquiterpenes; Therapeutic Equivalency | 1998 |
Plasma levels of artesunate and dihydroartemisinin in children with Plasmodium falciparum malaria in Gabon after administration of 50-milligram artesunate suppositories.
Topics: Absorption; Antimalarials; Artemisinins; Artesunate; Child; Female; Fever; Gabon; Humans; Malaria, Falciparum; Male; Parasitemia; Sesquiterpenes; Suppositories | 1998 |
A comparison of three different dihydroartemisinin formulations for the treatment of acute uncomplicated falciparum malaria in Thailand.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Animals; Antimalarials; Artemisia; Artemisinins; Chemistry, Pharmaceutical; Drug Evaluation; Female; Follow-Up Studies; Humans; Malaria, Falciparum; Male; Middle Aged; Phytotherapy; Plants, Medicinal; Sesquiterpenes; Thailand; Time Factors; Treatment Outcome | 1998 |
In vitro susceptibility of African Plasmodium falciparum isolates to dihydroartemisinin and the risk factors for resistance to qinghaosu.
Topics: Africa; Animals; Antimalarials; Artemisinins; Chloroquine; Cross Reactions; Drug Evaluation, Preclinical; Drug Resistance; France; Humans; Malaria, Falciparum; Mefloquine; Phenanthrenes; Plasmodium falciparum; Sesquiterpenes; Travel | 1998 |
[Efficacy of dihydroartemisinin in treatment of 37 malaria cases].
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Female; Humans; Malaria, Falciparum; Malaria, Vivax; Male; Middle Aged; Recurrence; Sesquiterpenes | 1997 |
Inoculum effect leads to overestimation of in vitro resistance for artemisinin derivatives and standard antimalarials: a Gambian field study.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Gambia; Hematocrit; Humans; Malaria, Falciparum; Mefloquine; Parasitemia; Phenanthrenes; Plasmodium falciparum; Quinine; Scintillation Counting; Sensitivity and Specificity; Sesquiterpenes | 1999 |
Efficient preparations of the beta-glucuronides of dihydroartemisinin and structural confirmation of the human glucuronide metabolite.
Topics: Antimalarials; Artemisinins; Chromatography, Liquid; Glucuronides; Humans; Malaria, Falciparum; Male; Mass Spectrometry; Sesquiterpenes; Stereoisomerism | 2001 |
Comparative pharmacokinetics and effect kinetics of orally administered artesunate in healthy volunteers and patients with uncomplicated falciparum malaria.
Topics: Administration, Oral; Adult; Antimalarials; Area Under Curve; Artemisinins; Artesunate; Chromatography, High Pressure Liquid; Humans; Malaria, Falciparum; Male; Sesquiterpenes | 2001 |