Page last updated: 2024-08-26

artenimol and Disease Models, Animal

artenimol has been researched along with Disease Models, Animal in 54 studies

Research

Studies (54)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (16.67)29.6817
2010's29 (53.70)24.3611
2020's16 (29.63)2.80

Authors

AuthorsStudies
Bane, CE; Bayles, BR; Black, C; Butler, K; Caridha, D; Ceja, FG; Cooper, RA; Dodean, RA; Gaona, H; Gaynor-Ohnstad, L; Kancharla, P; Kelly, JX; Kreishman-Deitrick, M; Leed, SE; Li, Q; Li, Y; Lin, H; Luong, TL; Marcsisin, S; Melendez, V; Mu, J; Nolan, C; Olmeda, R; Potter, B; Pou, S; Pybus, B; Rasmussen, SA; Read, L; Reynolds, KA; Riscoe, MK; Roncal, N; Rosenthal, PJ; Sciotti, RJ; Smilkstein, MJ; Sousa, J; Tumwebaze, PK; Vesely, B; Vuong, C; Xie, L; Zeng, Q; Zhang, J; Zhang, P1
Asakawa, AH; Brockmeyer, F; Casandra, D; Huang, L; Kyle, DE; LaCrue, AN; Maher, SP; Maignan, JR; Manetsch, R; Mashkouri, S; Monastyrskyi, A; Padin-Irizarry, V; Parvatkar, PT; Sakhno, YI; Zhao, Y1
Batty, KT; Law, AS; Moore, BR; Stirling, V1
Andrzejewski, C; Batty, KT; Ilett, KF; Jago, JD; Moore, BR; Page-Sharp, M1
Battistuzzi, G; Giannini, G; Vignola, D1
Chen, Y; Dong, Z; Du, Y; Li, J; Luo, M; Pang, Y; Wang, Y; Wu, B; Xia, L1
Bai, T; Li, M; Liu, B; Liu, Y; Qiao, Z; Wang, Z; Yang, L1
Bian, Z; Chen, M; Chen, YW; Fatima, S; Gong, R; Hu, X; Huang, T; Kwan, HY; Song, L; Wong, HLX; Yu, R1
Li, J; Lin, N; Liu, X; Mao, Z; Shi, Y; Wang, J; Wu, H; Xu, Q; Yang, J; Yao, X; Zhang, G; Zhu, C; Zhu, X; Zhu, Y1
Cui, Z; Guo, S; Jiang, T; Li, C; Li, L; Ma, J; Tang, T; Wang, H; Xu, W; Zhou, Y1
Chen, Y; Du, W; Hou, B; Jin, H; Li, H; Ma, Q; Mi, Y; Song, Y; Wang, D; Xing, J; Zhang, L; Zhang, X; Zou, Z1
Hao, CX; Huang, XT; Liu, W; Luo, ZQ; Sun, CC; Tang, SY; Zhang, CY; Zhou, Y1
Guo, J; Lei, Y; Lei, Z; Liu, S; Liu, W; Wu, H; Yang, C; Yang, L; Yang, Y; Zhang, X1
Chen, J; Chen, W; Dong, Q; Feng, P; Huang, W; Li, A; Li, H; Tang, M; Wang, R; Zhao, Y1
Chen, Y; Dai, Z; Han, L; Huang, RY; Liang, CL; Liu, H; Lu, C; Qiu, F; Yan, Y; Zhang, Q1
Gille, L; Machín, L; Monzote, L; Nápoles, R1
He, G; Idris, NFB; Liu, Y; Long, Z; Luo, M; Qiu, Y; Song, A; Wang, K; Zhao, Y1
Jin, Q; Liu, Y; Ma, L; Wu, J; Yang, X; Zhao, X1
He, D; Li, R; Lu, L; Wang, J; Yan, Q; Yin, H1
Cao, Y; Chen, A; Shao, J; Wang, X; Wang, Z; Wei, Z; Zhang, F; Zhang, Z; Zheng, S1
Gao, S; He, Y; Jiang, M; Sun, Q; Tang, D; Wang, D; Wang, L; Wu, X; You, X; Zhong, G; Zhu, Y1
Gong, W; Hu, Y; Jiang, L; Li, H; Liang, H; Liu, Y; Ma, Q; Wang, X; Wang, Z; Xiang, S; Xu, Z; Ye, Y; Zhang, F; Zhang, Y1
Bai, J; Li, J; Li, S; Li, X; Shi, X; Wang, L; Wang, Z; Zhou, M1
Achieng, AO; Ghosh, PC; Kempaiah, P; Kumar, P; Perkins, DJ; Rajendran, V; Rathi, B; Rawat, M; Singh, BK1
Allen, TD; Cheng, Z; Li, L; Liu, J; Liu, Q; Pan, S; Qi, R; Xu, D; Zhang, W; Zhou, X1
Chen, Z; Ge, X; Lv, F; Xu, Z; Yang, Y; Zhang, K1
Fan, M; Li, Y; Liu, J; Liu, X; Yao, C1
Chen, X; Chen, Z; Dai, G; Du, Y; He, Y; Liu, P; Liu, Y; Mo, M; Xia, W; Zhang, B; Zhou, Y1
Ji, W; Zhu, H1
Cai, WY; Chen, Y; Li, Q; Li, YJ; Wang, YJ; Weng, XG; Yan, SC; Yang, Q; Zhu, XX1
Briolant, S; Desgrouas, C; Dormoi, J; Pradines, B1
Chu, X; Guan, M; Wang, D; Wei, M; Xie, X; Yang, X1
Dormoi, J; Pradines, B1
Briolant, S; Desgrouas, C; Dormoi, J; Pascual, A; Pradines, B; Travaillé, C1
Dai, JR; Li, HJ; Liang, YS; Qu, GL; Wang, W; Xing, YT; Yang, ZK1
Batty, KT; Gibbons, PL; Kirkpatrick, CM; Moore, BR; Patel, K1
Agnamey, P; Degrouas, C; Jonet, A; Mullié, C; Pascual, A; Sonnet, P; Taudon, N1
Cabral, L; Cristiano, ML; Lobo, L; Nogueira, F; Sousa, Bd1
Anh, DT; Ishida, N; Kume, A; Shichiri, M; Suzuki, H1
Ba, Q; Chen, K; Chen, T; Li, J; Li, X; Liu, H; Liu, Y; Wang, H; Zhang, X; Zhou, Y1
Chen, YF; Cui, Y; Dai, XD; Nie, DP; Qin, YH; Ren, YX; Zheng, LL1
Abiodun, O; Bell, A; Brun, R; Chollet, J; Irungu, BN; Kiboi, DM; Langat, B; Nganga, JK; Nyambati, VC; Nzila, A; Rukunga, GM; Wittlin, S1
Aung, W; Furukawa, T; Saga, T; Sogawa, C1
Dai, JR; Li, HJ; Li, YZ; Liang, YS; Qu, GL; Tao, YH; Wang, W; Wei, JY; Xing, YT2
Batty, KT; Ilett, KF; Jago, JD; Moore, BR; Page-Sharp, M; Stoney, JR1
Coles, GC; Dai, JR; Dai, Y; Li, HJ; Li, YZ; Liang, YS; Qu, GL; Tao, YH; Wang, W; Wang, XT; Wei, JY; Xing, YT1
Liu, G; Liu, YX; Wang, YY; Xie, QB1
Keiser, J; Shu-Hua, X; Tanner, M; Utzinger, J1
Godin, B; Golenser, J; Touitou, E; Waknine, JH1
Barrett, PH; Batty, KT; Davis, TM; Gibbons, PL; Ilett, KF1
Batty, KT; Jago, JD; Moore, BR1
Batty, KT; Davis, TM; Gibbons, PL; Ilett, KF1
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV1

Other Studies

54 other study(ies) available for artenimol and Disease Models, Animal

ArticleYear
Lead Optimization of Second-Generation Acridones as Broad-Spectrum Antimalarials.
    Journal of medicinal chemistry, 2020, 06-11, Volume: 63, Issue:11

    Topics: Acridones; Administration, Oral; Animals; Antimalarials; Cell Survival; Disease Models, Animal; Female; Half-Life; Hep G2 Cells; Humans; Life Cycle Stages; Malaria; Male; Mice; Mice, Inbred C57BL; Plasmodium falciparum; Structure-Activity Relationship

2020
Aminoalkoxycarbonyloxymethyl Ether Prodrugs with a pH-Triggered Release Mechanism: A Case Study Improving the Solubility, Bioavailability, and Efficacy of Antimalarial 4(1
    Journal of medicinal chemistry, 2021, 05-27, Volume: 64, Issue:10

    Topics: Administration, Oral; Animals; Antimalarials; Cyclization; Disease Models, Animal; Ethers; Female; Half-Life; Hydrogen-Ion Concentration; Malaria; Mice; Mice, Inbred BALB C; Plasmodium falciparum; Prodrugs; Quinolones; Solubility; Structure-Activity Relationship

2021
Pharmacodynamics of doxycycline in a murine malaria model.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:12

    Topics: Animals; Antimalarials; Artemisinins; Disease Models, Animal; Doxycycline; Drug Synergism; Drug Therapy, Combination; Malaria; Male; Mice; Mice, Inbred BALB C; Plasmodium berghei; Sesquiterpenes

2007
Pharmacokinetics and pharmacodynamics of piperaquine in a murine malaria model.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:1

    Topics: Animals; Antimalarials; Artemisinins; Disease Models, Animal; Drug Therapy, Combination; Humans; Malaria; Male; Mice; Parasitemia; Plasmodium berghei; Quinolines; Sesquiterpenes; Treatment Outcome

2008
Hydroxamic acid based histone deacetylase inhibitors with confirmed activity against the malaria parasite.
    Bioorganic & medicinal chemistry letters, 2015, Feb-01, Volume: 25, Issue:3

    Topics: Animals; Antimalarials; Cell Line, Tumor; Dipeptides; Disease Models, Animal; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Malaria; Mice; Parasites; Plasmodium falciparum; Protein Isoforms

2015
Dihydroartemisinin Induces O-GlcNAcylation and Improves Cognitive Function in a Mouse Model of Tauopathy.
    Journal of Alzheimer's disease : JAD, 2021, Volume: 84, Issue:1

    Topics: Alzheimer Disease; Animals; Antimalarials; Artemisinins; Brain; Cognition; Disease Models, Animal; Humans; Learning; Long-Term Potentiation; Mice; Neuroprotective Agents; Phosphorylation; Tauopathies

2021
Dihydroartemisinin triggers ferroptosis in primary liver cancer cells by promoting and unfolded protein response‑induced upregulation of CHAC1 expression.
    Oncology reports, 2021, Volume: 46, Issue:5

    Topics: Animals; Artemisinins; Cell Line, Tumor; Disease Models, Animal; Ferroptosis; gamma-Glutamylcyclotransferase; Humans; Liver Neoplasms; Mice; RNA, Small Interfering; Unfolded Protein Response; Up-Regulation

2021
Dihydroartemisinin is potential therapeutics for treating late-stage CRC by targeting the elevated c-Myc level.
    Cell death & disease, 2021, 11-05, Volume: 12, Issue:11

    Topics: Animals; Apoptosis; Artemisinins; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Disease Models, Animal; Energy Metabolism; Fatty Acids; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; Ki-67 Antigen; Lipid Metabolism; Luminescent Measurements; Mice, Inbred BALB C; Mice, Nude; Neoplasm Staging; Phenotype; Principal Component Analysis; Proto-Oncogene Proteins c-myc; Transcription, Genetic

2021
The analgesic and antidepressant properties of dihydroartemisinine in the neuropathic pain mice: By the downregulation of HnRNPA1 in the spinal cord and hippocampus.
    Clinical and translational medicine, 2022, Volume: 12, Issue:2

    Topics: Analgesics; Animals; Antidepressive Agents; Artemisinins; Disease Models, Animal; Heterogeneous Nuclear Ribonucleoprotein A1; Hippocampus; Mice; Neuralgia; Spinal Cord

2022
Effect of Dihydroartemisinin on
    The American journal of Chinese medicine, 2019, Volume: 47, Issue:6

    Topics: Animals; Antimalarials; Artemisinins; Azaserine; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression; Glutamate Synthase (NADH); Glutamic Acid; Humans; Malaria; Mice, Inbred C57BL; Phytotherapy; Plasmodium falciparum

2019
Dihydroartemisinin-induced unfolded protein response feedback attenuates ferroptosis via PERK/ATF4/HSPA5 pathway in glioma cells.
    Journal of experimental & clinical cancer research : CR, 2019, Sep-13, Volume: 38, Issue:1

    Topics: Activating Transcription Factor 4; Animals; Artemisinins; Biomarkers; Cell Line, Tumor; Cell Survival; Disease Models, Animal; eIF-2 Kinase; Endoplasmic Reticulum Chaperone BiP; Ferroptosis; Gene Expression; Glioma; Heat-Shock Proteins; Humans; Mice; Reactive Oxygen Species; Signal Transduction; Unfolded Protein Response

2019
Dihydroartemisinin attenuates lipopolysaccharide‑induced acute lung injury in mice by suppressing NF‑κB signaling in an Nrf2‑dependent manner.
    International journal of molecular medicine, 2019, Volume: 44, Issue:6

    Topics: Acute Lung Injury; Animals; Artemisinins; Disease Models, Animal; Humans; Inflammation; Lipopolysaccharides; Lung; Macrophages; Mice; NF-E2-Related Factor 2; NF-kappa B; Signal Transduction; Tumor Necrosis Factor-alpha

2019
Dihydroartemisinin ameliorates dextran sulfate sodium induced inflammatory bowel diseases in mice.
    Bioorganic chemistry, 2020, Volume: 100

    Topics: Animals; Antimalarials; Artemisinins; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Microbiome; Inflammatory Bowel Diseases; Male; Mice; Mice, Inbred C57BL

2020
Dihydroartemisinin Attenuates Pulmonary Hypertension Through Inhibition of Pulmonary Vascular Remodeling in Rats.
    Journal of cardiovascular pharmacology, 2020, Volume: 76, Issue:3

    Topics: Adaptor Proteins, Signal Transducing; Animals; Antihypertensive Agents; Artemisinins; Arterial Pressure; beta Catenin; Carrier Proteins; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Glycogen Synthase Kinase 3 beta; Male; Monocrotaline; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Pulmonary Arterial Hypertension; Pulmonary Artery; Rats, Sprague-Dawley; Vascular Remodeling; Wnt Signaling Pathway

2020
Dihydroartemisinin ameliorates psoriatic skin inflammation and its relapse by diminishing CD8
    Theranostics, 2020, Volume: 10, Issue:23

    Topics: Animals; Artemisinins; CD8-Positive T-Lymphocytes; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Imiquimod; Immunologic Memory; Interleukin-15; Interleukin-17; Male; Methotrexate; Mice; Psoriasis; Recurrence; Secondary Prevention; Skin; Skin Transplantation; Transplantation Chimera

2020
Leishmania amazonensis response to artemisinin and derivatives.
    Parasitology international, 2021, Volume: 80

    Topics: Animals; Artemether; Artemisinins; Artesunate; Disease Models, Animal; Female; Leishmania mexicana; Mice; Mice, Inbred BALB C; Parasite Load; Trypanocidal Agents

2021
Dihydroartemisinin Ameliorates Decreased Neuroplasticity-Associated Proteins and Excessive Neuronal Apoptosis in APP/PS1 Mice.
    Current Alzheimer research, 2020, Volume: 17, Issue:10

    Topics: Alzheimer Disease; Animals; Antimalarials; Apoptosis; Artemisinins; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Hippocampus; Humans; Male; Memory; Mice; Mice, Transgenic; Neuronal Plasticity; Neuroprotective Agents

2020
Dihydroartemisinin attenuates osteoarthritis by inhibiting abnormal bone remodeling and angiogenesis in subchondral bone.
    International journal of molecular medicine, 2021, Volume: 47, Issue:3

    Topics: Animals; Artemisinins; Bone and Bones; Bone Remodeling; Disease Models, Animal; Female; Mice; Neovascularization, Physiologic; Osteoarthritis

2021
Dihydroartemisinin alleviates skin fibrosis and endothelial dysfunction in bleomycin-induced skin fibrosis models.
    Clinical rheumatology, 2021, Volume: 40, Issue:10

    Topics: Animals; Artemisinins; Bleomycin; Disease Models, Animal; Fibroblasts; Fibrosis; Human Umbilical Vein Endothelial Cells; Humans; Mice; Phosphatidylinositol 3-Kinases; Scleroderma, Systemic; Skin

2021
Dihydroartemisinin alleviates hepatic fibrosis through inducing ferroptosis in hepatic stellate cells.
    BioFactors (Oxford, England), 2021, Volume: 47, Issue:5

    Topics: Animals; Artemisinins; Disease Models, Animal; Ferroptosis; Hepatic Stellate Cells; Liver Cirrhosis; Male; Rats; Rats, Sprague-Dawley; Signal Transduction

2021
Retardant effect of dihydroartemisinin on ulcerative colitis in a JAK2/STAT3-dependent manner.
    Acta biochimica et biophysica Sinica, 2021, Aug-31, Volume: 53, Issue:9

    Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Artemisinins; Caco-2 Cells; Cell Survival; Colitis, Ulcerative; Dextran Sulfate; Disease Models, Animal; Humans; Interleukins; Janus Kinase 2; Male; Mice, Inbred C57BL; Occludin; STAT3 Transcription Factor; THP-1 Cells; Zonula Occludens-1 Protein

2021
Dihydroartemisinin inhibits TCTP-dependent metastasis in gallbladder cancer.
    Journal of experimental & clinical cancer research : CR, 2017, 05-15, Volume: 36, Issue:1

    Topics: Animals; Antineoplastic Agents; Artemisinins; Biomarkers, Tumor; cdc42 GTP-Binding Protein; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Models, Animal; Female; Gallbladder Neoplasms; Heterografts; Humans; Mice; Neoplasm Metastasis; Neoplasm Staging; Tumor Protein, Translationally-Controlled 1

2017
Dihydroartemisinin induces autophagy-dependent death in human tongue squamous cell carcinoma cells through DNA double-strand break-mediated oxidative stress.
    Oncotarget, 2017, Jul-11, Volume: 8, Issue:28

    Topics: Animals; Artemisinins; Autophagy; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; DNA Breaks, Double-Stranded; Humans; Models, Biological; Oxidative Stress; STAT3 Transcription Factor; Tongue Neoplasms; Tumor Burden; Xenograft Model Antitumor Assays

2017
Synergistic blending of high-valued heterocycles inhibits growth of Plasmodium falciparum in culture and P. berghei infection in mouse model.
    Scientific reports, 2017, 07-27, Volume: 7, Issue:1

    Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Erythrocytes; Female; Humans; Inhibitory Concentration 50; Life Cycle Stages; Malaria; Mice; Phthalimides; Plasmodium berghei; Plasmodium falciparum

2017
Dihydroartemisinin ameliorates sepsis-induced hyperpermeability of glomerular endothelium via up-regulation of occludin expression.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 99

    Topics: Acute Kidney Injury; Animals; Apoptosis; Artemisinins; Cell Survival; Disease Models, Animal; Endothelial Cells; Endothelium; Humans; Kidney Glomerulus; Lipopolysaccharides; Mice, Inbred C57BL; Occludin; Permeability; Sepsis; Tumor Necrosis Factor-alpha; Up-Regulation

2018
The effects of dihydroartemisinin on inflammatory bowel disease-related bone loss in a rat model.
    Experimental biology and medicine (Maywood, N.J.), 2018, Volume: 243, Issue:8

    Topics: Animals; Anti-Inflammatory Agents; Artemisinins; Bone Density Conservation Agents; Bone Diseases, Metabolic; Dextran Sulfate; Disease Models, Animal; Inflammatory Bowel Diseases; Injections, Intraperitoneal; Male; Rats, Sprague-Dawley; Treatment Outcome

2018
Dihydroartemisinin derivative DC32 attenuates collagen-induced arthritis in mice by restoring the Treg/Th17 balance and inhibiting synovitis through down-regulation of IL-6.
    International immunopharmacology, 2018, Volume: 65

    Topics: Animals; Antirheumatic Agents; Artemisinins; Arthritis, Experimental; Cells, Cultured; Disease Models, Animal; Down-Regulation; Humans; Interleukin-6; Male; Mice; Mice, Inbred DBA; Rats; Rats, Sprague-Dawley; Synovitis; T-Lymphocytes, Regulatory; Th17 Cells

2018
Dihydroartemisinin attenuates renal fibrosis through regulation of fibroblast proliferation and differentiation.
    Life sciences, 2019, Apr-15, Volume: 223

    Topics: Animals; Artemisinins; Cell Differentiation; Cell Proliferation; Disease Models, Animal; Fibroblasts; Fibrosis; Kidney; Male; Mice, Inbred C57BL; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Ureteral Obstruction

2019
Dihydroartemisinin Ameliorated Ovalbumin-Induced Asthma in Mice via Regulation of MiR-183C.
    Medical science monitor : international medical journal of experimental and clinical research, 2019, May-22, Volume: 25

    Topics: Allergens; Animals; Artemisinins; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Female; Forkhead Transcription Factors; Lung; Mice; Mice, Inbred BALB C; MicroRNAs; Ovalbumin; STAT3 Transcription Factor; T-Lymphocytes, Regulatory; Th17 Cells

2019
Dihydroartemisinin Regulates the Th/Treg Balance by Inducing Activated CD4+ T cell Apoptosis via Heme Oxygenase-1 Induction in Mouse Models of Inflammatory Bowel Disease.
    Molecules (Basel, Switzerland), 2019, Jul-05, Volume: 24, Issue:13

    Topics: Animals; Apoptosis; Artemisinins; Colitis; Disease Models, Animal; Enzyme Induction; Heme Oxygenase-1; Inflammatory Bowel Diseases; Lymphocyte Activation; Lymphocyte Subsets; Mice; Oxazolone; T-Lymphocytes, Helper-Inducer; T-Lymphocytes, Regulatory; Trinitrobenzenesulfonic Acid

2019
Efficacy of proveblue (methylene blue) in an experimental cerebral malaria murine model.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:7

    Topics: Animals; Antimalarials; Artemisinins; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inhibitors; Female; Malaria, Cerebral; Methylene Blue; Mice; Mice, Inbred C57BL; Plasmodium berghei

2013
Dihydroartemisinin suppresses ovalbumin-induced airway inflammation in a mouse allergic asthma model.
    Immunopharmacology and immunotoxicology, 2013, Volume: 35, Issue:3

    Topics: Animals; Anti-Asthmatic Agents; Artemisinins; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Female; Goblet Cells; Immunoglobulin E; Inflammation; Inflammation Mediators; Mice; Mice, Inbred BALB C; Mucus; Ovalbumin; Respiratory Hypersensitivity; Respiratory System; Th2 Cells

2013
Dose responses of proveblue methylene blue in an experimental murine cerebral malaria model.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:8

    Topics: Animals; Antimalarials; Artemisinins; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Synergism; Erythrocytes; Female; Kaplan-Meier Estimate; Malaria, Cerebral; Methylene Blue; Mice; Mice, Inbred C57BL; Plasmodium berghei; Time Factors; Treatment Outcome

2013
Improvement of the efficacy of dihydroartemisinin with atorvastatin in an experimental cerebral malaria murine model.
    Malaria journal, 2013, Aug-30, Volume: 12

    Topics: Animals; Anti-Inflammatory Agents; Antimalarials; Artemisinins; Atorvastatin; Biomarkers; Disease Models, Animal; Drug Therapy, Combination; Female; Heptanoic Acids; Inflammation; Malaria, Cerebral; Mice; Mice, Inbred C57BL; Pyrroles; Survival Analysis; Treatment Outcome

2013
Is there a reduced sensitivity of dihydroartemisinin against praziquantel-resistant Schistosoma japonicum?
    Parasitology research, 2014, Volume: 113, Issue:1

    Topics: Animals; Artemisinins; Disease Models, Animal; Drug Resistance; Female; Mice; Mice, Inbred ICR; Praziquantel; Schistosoma japonicum; Schistosomiasis japonica; Schistosomicides

2014
Predicting the parasite killing effect of artemisinin combination therapy in a murine malaria model.
    The Journal of antimicrobial chemotherapy, 2014, Volume: 69, Issue:8

    Topics: Animals; Antimalarials; Artemisinins; Disease Models, Animal; Drug Combinations; Malaria; Mice; Parasite Load; Parasitic Sensitivity Tests; Plasmodium berghei; Quinolines; Recurrence

2014
Enantiomerically pure amino-alcohol quinolines: in vitro anti-malarial activity in combination with dihydroartemisinin, cytotoxicity and in vivo efficacy in a Plasmodium berghei mouse model.
    Malaria journal, 2014, Oct-16, Volume: 13

    Topics: Animals; Antimalarials; Artemisinins; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Erythrocytes; Female; Hemolysis; Inhibitory Concentration 50; Malaria; Mice, Inbred BALB C; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Survival Analysis; Treatment Outcome

2014
Highly active ozonides selected against drug resistant malaria.
    Memorias do Instituto Oswaldo Cruz, 2016, Jun-07, Volume: 0

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Disease Models, Animal; Female; Humans; Malaria, Falciparum; Mefloquine; Mice; Parasitemia; Plasmodium falciparum

2016
Probucol dramatically enhances dihydroartemisinin effect in murine malaria.
    Malaria journal, 2016, 09-15, Volume: 15

    Topics: Animals; Antimalarials; Artemisinins; Chemoprevention; Disease Models, Animal; Malaria; Male; Mice, Inbred C57BL; Plasmodium yoelii; Probucol; Treatment Outcome

2016
Preclinical Efficacy and Safety Assessment of Artemisinin-Chemotherapeutic Agent Conjugates for Ovarian Cancer.
    EBioMedicine, 2016, Volume: 14

    Topics: Animals; Antineoplastic Agents; Apoptosis; Artemisinins; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Models, Animal; Drug Combinations; Drug Evaluation, Preclinical; Epithelial-Mesenchymal Transition; Female; Humans; Mice; Neoplasm Metastasis; Neoplasm Staging; Ovarian Neoplasms; Structure-Activity Relationship; Xenograft Model Antitumor Assays

2016
[Experimental treatment using combined Fructus psoraleae and dihydroartemisinin in mouse cryptosporidiosis].
    Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 2008, Feb-28, Volume: 26, Issue:1

    Topics: Animals; Artemisinins; CD3 Complex; CD4 Antigens; Cryptosporidiosis; Cryptosporidium parvum; Disease Models, Animal; Drug Therapy, Combination; Ficusin; Interferon-gamma; Intestinal Mucosa; Intestines; Male; Mice; Mice, Inbred Strains; Nitric Oxide; T-Lymphocytes; Treatment Outcome

2008
Plasmodium berghei ANKA: selection of resistance to piperaquine and lumefantrine in a mouse model.
    Experimental parasitology, 2009, Volume: 122, Issue:3

    Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Chloroquine; Disease Models, Animal; Drug Resistance; Ethanolamines; Female; Fluorenes; Lumefantrine; Malaria; Male; Mice; Parasitemia; Plasmodium berghei; Quinolines; Serial Passage

2009
Anticancer effect of dihydroartemisinin (DHA) in a pancreatic tumor model evaluated by conventional methods and optical imaging.
    Anticancer research, 2011, Volume: 31, Issue:5

    Topics: Animals; Antimalarials; Apoptosis; Artemisinins; Biomarkers, Tumor; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Diagnostic Imaging; Disease Models, Animal; Flow Cytometry; Fluorescent Antibody Technique; Humans; Immunoenzyme Techniques; Mice; Mice, Nude; Pancreatic Neoplasms; Xenograft Model Antitumor Assays

2011
Effects of artemether, artesunate and dihydroartemisinin administered orally at multiple doses or combination in treatment of mice infected with Schistosoma japonicum.
    Parasitology research, 2011, Volume: 109, Issue:2

    Topics: Administration, Oral; Animals; Antiprotozoal Agents; Artemether; Artemisinins; Artesunate; Disease Models, Animal; Female; Mice; Rodent Diseases; Schistosoma japonicum; Schistosomiasis japonica; Treatment Outcome

2011
Pharmacokinetics, pharmacodynamics, and allometric scaling of chloroquine in a murine malaria model.
    Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:8

    Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Chromatography, High Pressure Liquid; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Malaria; Male; Mice; Mice, Inbred BALB C; Parasitemia; Plasmodium berghei

2011
Dihydroartemisinin-praziquantel combinations and multiple doses of dihydroartemisinin in the treatment of Schistosoma japonicum in experimentally infected mice.
    Annals of tropical medicine and parasitology, 2011, Volume: 105, Issue:4

    Topics: Animals; Anthelmintics; Artemisinins; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Drug Evaluation, Preclinical; Female; Male; Mice; Parasitic Diseases, Animal; Parasitic Sensitivity Tests; Praziquantel; Schistosoma japonicum; Schistosomiasis japonica; Treatment Outcome

2011
Effect of the in vivo activity of dihydroartemisinin against Schistosoma mansoni infection in mice.
    Parasitology research, 2012, Volume: 110, Issue:5

    Topics: Administration, Oral; Animals; Anthelmintics; Artemisinins; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Mice; Parasite Load; Schistosoma mansoni; Schistosomiasis mansoni; Treatment Outcome

2012
[Effects of dihydroartemisinin on collagen II-induced arthritis in rats model].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2012, Volume: 43, Issue:6

    Topics: Animals; Artemisia; Artemisinins; Arthritis; Collagen Type II; Disease Models, Animal; Male; Rats; Rats, Wistar

2012
Artesunate and artemether are effective fasciolicides in the rat model and in vitro.
    The Journal of antimicrobial chemotherapy, 2006, Volume: 57, Issue:6

    Topics: Animals; Antiplatyhelmintic Agents; Artemether; Artemisinins; Artesunate; Bile Ducts; Disease Models, Animal; Fasciola hepatica; Fascioliasis; Female; Microscopy, Electron, Scanning; Rats; Rats, Wistar; Sesquiterpenes

2006
Treatment of malaria in a mouse model by intranasal drug administration.
    International journal for parasitology, 2006, Volume: 36, Issue:14

    Topics: Administration, Intranasal; Animals; Antimalarials; Artemisinins; Disease Models, Animal; Drug Administration Schedule; Female; Malaria; Malaria, Cerebral; Mice; Mice, Inbred ICR; Parasitemia; Plasmodium berghei; Sesquiterpenes; Survival Analysis; Treatment Outcome

2006
Development of a pharmacodynamic model of murine malaria and antimalarial treatment with dihydroartemisinin.
    International journal for parasitology, 2007, Volume: 37, Issue:14

    Topics: Animals; Antimalarials; Artemisinins; Disease Models, Animal; Dose-Response Relationship, Drug; Erythrocyte Count; Erythrocytes; Malaria; Male; Mice; Mice, Inbred BALB C; Parasitemia; Plasmodium berghei; Sesquiterpenes

2007
Plasmodium berghei: parasite clearance after treatment with dihydroartemisinin in an asplenic murine malaria model.
    Experimental parasitology, 2008, Volume: 118, Issue:4

    Topics: Animals; Antimalarials; Artemisinins; Aspartate Aminotransferases; Disease Models, Animal; Erythrocytes; Hemeproteins; Hemoglobins; Leukocyte Count; Liver; Lung; Malaria; Male; Mice; Mice, Inbred BALB C; Parasitemia; Plasmodium berghei; Platelet Count; Sesquiterpenes; Spleen; Splenectomy

2008
Pharmacokinetics of dihydroartemisinin in a murine malaria model.
    The American journal of tropical medicine and hygiene, 2008, Volume: 78, Issue:4

    Topics: Animals; Antimalarials; Artemisinins; Disease Models, Animal; Humans; Malaria; Metabolic Clearance Rate; Mice; Rats; Species Specificity

2008
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

2020