artemisinin has been researched along with Malaria in 644 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 38 (5.90) | 18.7374 |
| 1990's | 46 (7.14) | 18.2507 |
| 2000's | 128 (19.88) | 29.6817 |
| 2010's | 338 (52.48) | 24.3611 |
| 2020's | 94 (14.60) | 2.80 |
| Authors | Studies |
|---|---|
| Cassera, MB; Dalal, S; Goetz, M; Kingston, DG; Su, Q | 1 |
| Avery, VM; Baragaña, B; Campbell, SF; Delves, MJ; Duffy, S; Fairlamb, AH; Frearson, JA; Gilbert, IH; Gray, DW; Grimaldi, R; Hallyburton, I; Meister, S; Norcross, NR; Norval, S; Osuna-Cabello, M; Porzelle, A; Read, KD; Riley, J; Simeons, FR; Sinden, RE; Stojanovski, L; Waterson, D; Willis, P; Wilson, C; Winzeler, EA; Wittlin, S; Wyatt, PG | 1 |
| Mahajan, S; Vijayaraghavan, S | 1 |
| Bordignon, A; Cieckiewicz, E; Di Giovanni, N; Frédérich, M; Hoareau, F; Illien, B; Jansen, O; Ledoux, A; Marvilliers, A; Pendeville, H; Quetin-Leclercq, J; St-Gelais, A | 1 |
| Berry, P; Campo, B; Cao, J; Ciaravino, V; Easom, EE; Erve, JCL; Freund, YR; Gamo, FJ; Guo, D; Jacobs, RT; Plattner, JJ; Rosenthal, PJ; Sanz, LM; Zhang, YK | 1 |
| Amendola, G; Chouchene, K; Cosconati, S; Ettari, R; Grasso, S; Gut, J; Hellmich, UA; Krauth-Siegel, RL; Previti, S; Rosenthal, PJ; Schirmeister, T; Schmid, I; Ulrich, K; Wagner, A; Wich, PR; Zappalà, M | 1 |
| Chen, W; Guan, L; Huang, J; Huang, Z; Jiang, H; Jiang, L; Li, J; Mao, F; Tang, Y; Wang, W; Zhu, J | 1 |
| Adah, D; Chen, X; Dai, L; Goldberg, DE; Guan, J; Leng, F; Li, X; Liu, J; Liu, X; Liu, Z; Lu, Y; Ma, H; McNitt, SA; Meyers, MJ; Nasamu, AS; Polino, AJ; Qin, L; Tortorella, MD; Tu, Z; Xu, J; Zhao, S | 1 |
| Faist, J; Hochegger, P; Kaiser, M; Mäser, P; Saf, R; Seebacher, W; Weis, R | 1 |
| Cheong, SL; Ng, CH; Tibon, NS | 1 |
| Abramo, C; David da Silva, A; de Almeida Pimentel, G; de Pilla Varotti, F; Glanzmann, N; Gualberto Pereira, HM; Karine da Costa Nunes, I; Marinho, JA; Martins Guimarães, DS; Navarro, M | 1 |
| Aratikatla, EK; Asad, M; Bhattacharya, AK; Datta, G; Kalamuddin, M; Malhotra, P; Mohmmed, A; Rana, KC; Sundararaman, S | 1 |
| Hassam, M; Kumar Yadav, D; Prakash Verma, V; Puri, SK; Sharma, S; Shrivastava, R; Shukla, M; Singh, C | 1 |
| Hassam, M; Karnatak, M; Kumar Yadav, D; Prakash Verma, V; Puri, SK; Rawat, V; Sharma, S; Singh, C; Vanangamudi, M | 1 |
| Hassam, M; Karnatak, M; Puri, SK; Singh, AS; Singh, C; Verma, VP; Yadav, DK | 1 |
| Amaratunga, C; Bolarinwa, OA; Boon, WPC; Cheah, PY; de Haan, F; Dhorda, M; Dondorp, AM; Guissou, R; Mokuolu, OA; Moors, EHM; Ouedraogo, JB; Tindana, P; Tou, F | 1 |
| Borrmann, S; Nordmann, T; Ramharter, M | 1 |
| Barton, M; Brooks, HM; Forgie, EME; Hawkes, MT | 1 |
| Cooper, RA; Kirkman, L | 1 |
| Anibogwu, R; Jesus, K; Mateen, S; Pashikanti, S; Pradhan, S; Sharma, K | 1 |
| Bachmann, A; Bergmann, B; Bozdech, Z; Castro-Peña, C; Davioud-Charvet, E; Elhabiri, M; Gilberger, TW; Mesén-Ramírez, P; Spielmann, T; von Thien, H; Zhu, L | 1 |
| Abbas, FB; Al-Mafazy, AW; Ali, AS; Ali, MH; Bisanzio, D; Eckert, E; Hassan, WS; Joseph, JJ; Kabula, BI; Kitojo, C; Lalji, SM; McKay, M; Mkali, HR; Ngondi, JM; Nyinondi, SS; Reaves, EJ; Reithinger, R; Serbantez, N | 1 |
| Guntur, RD; Islam, FMA; Kingsley, J | 1 |
| Guo, Q; Lin, L; Shi, Z; Tang, Z; Xiong, H | 1 |
| Cui, Z; Jiang, T; Li, C; Li, L; Li, S; Ma, J; Qin, T; Shi, H; Tang, T; Wang, H; Xu, W; Zhou, H | 1 |
| Camara, M; Ferreira, MU; Gil, JP; Morris, U; Nóbrega de Sousa, T; Pernaute-Lau, L | 1 |
| Fidock, DA; Stokes, BH; Ward, KE | 1 |
| Balikagala, B; Fukuda, N; Mita, T | 1 |
| Creek, DJ; Dogovski, C; Du, Y; Giannangelo, C; He, W; Li, X; Shami, GJ; Tilley, L; Yang, T; Zhou, W | 1 |
| Jiang, T; Liao, FL; Tu, Y; Wang, J; Wong, YK; Xu, C | 1 |
| Rasmussen, C; Ringwald, P | 1 |
| Clark, RL | 2 |
| Fleckenstein, L; Miller, RM | 1 |
| Grundmann, O; Maldonado, JH | 1 |
| Bassat, Q; Cortés, A; Guetens, P; Millogo, A; Natama, HM; Ouédraogo, DF; Portugaliza, HP; Rosanas-Urgell, A; Rovira-Vallbona, E; Sitoe, A; Somé, AM; Sorgho, H; Tinto, H; Valéa, I; van Hong, N; Varo, R | 1 |
| Abdallah, KS; Bacar, A; Deng, C; Li, G; Li, M; Liu, R; Lu, C; Silai, R; Song, J; Tan, R; Wu, W; Xu, Q; Yuan, Y; Zhang, H; Zheng, S | 1 |
| Bamadio, A; Chico, RM; Cohee, LM; Coumare, S; Dara, A; Diarra, M; Djimde, AA; Doumbo, OK; Kodio, A; Maiga, H; Opondo, C; Sagara, I; Sidibe, B; Tekete, M; Traore, OB; Traore, ZI | 1 |
| Adewole, AO; Ajumobi, O; Asamoa, K; Bala, U; Cash, S; Gidado, S; Isaac, I; Kachur, SP; Nguku, P; Saleh, A; Simple, E; Ugbenyo, G; Umar, A; Waziri, N; Yoon, S | 1 |
| Aweeka, F; Ehrlich, H; Freeman, T; French, J; Goodwin, J; Huang, L; Kajubi, R; Kay, K; Li, F; Mwebaza, N; Ou, J; Parikh, S; Riggs, M; Ruiz-Garcia, A; Wade, M; Wang, K | 1 |
| Anam, Z; Bhattacharjee, S; Chaurasiya, A; Das, G; Dubey, N; Garg, S; Gupta, K; Joshi, N; Joshi, P; Kahlon, AK; Kaushik, S; Kumari, G; Kumari, J; Marothia, M; Maurya, MK; Ranganathan, A; Saini, S; Shoaib, R; Singh, N; Singh, S; Singhal, J; Srivastava, P | 1 |
| Abo-Dya, NE; Alahmdi, MI; Kumi, RO; Oti, B; Soliman, MES | 1 |
| Augusto, O; Byamugisha, J; Clerk, C; Dellicour, S; Desai, M; Gomes, M; Guérin, PJ; Hill, J; Kagawa, M; Kariuki, S; Kisinza, W; Manyando, C; McGready, R; Mehta, U; Mosha, D; Mrema, S; Njunju, EM; Nosten, F; Rouamba, T; Rulisa, S; Saito, M; Sevene, E; Singlovic, J; Stepniewska, K; Stergachis, A; Ter Kuile, FO; Tinto, H; Vala, A; van Eijk, AM; Were, E; Yore, M | 1 |
| Barry, AE | 1 |
| Arora, P; Malhotra, P; Mohmmed, A; Mukhtar, O; Narwal, M; Thakur, V | 1 |
| Ganguly, R; Khaw, LT; Lai, JW; Lim, YAL; Maah, MJ; Ng, CH; Sarip, R; Tan, KW | 1 |
| Chen, D; Chen, L; He, B; Li, Y; Zeng, ZW | 1 |
| Adjei, GO; Ahorhorlu, SY; Alifrangis, M; Duah-Quashie, NO; Dzudzor, B; Hansson, H; Jensen, RW; Kudzi, W; Nartey, ET; Quashie, NB; Wang, CW; Zoiku, F | 1 |
| Abala, C; Nyeko, R; Obiya, EM; Otim, F | 1 |
| Baharav, N; Schwartz, E | 1 |
| Akala, HM; Amwoma, JG; Andagalu, BM; Chemwor, GC; Cheruiyot, AC; Egbo, TE; Garges, EC; Juma, DW; Juma, JA; Kamau, E; Mwakio, EW; Ogutu, BR; Okoth, RO; Onyango, IA; Opot, BH; Roth, AL; Wakoli, DM; Watson, OJ; Yedah, RA | 1 |
| Aryal, A; Brown, AC; Guler, JL; Liu, S; Warthan, MD | 1 |
| Chaijaroenkul, W; Jalei, AA; Muhamad, P; Na-Bangchang, K | 1 |
| Fan, H; Guan, L; Wang, H; Xu, X | 1 |
| Adetunji, CO; Armstrong, L; Calina, D; Cho, WC; Fokou, PVT; Giordo, R; Gulsunoglu-Konuskan, Z; Habtemariam, S; Martorell, M; Modu, B; Mohammed, SA; Orhan, IE; Pintus, G; Posadino, AM; Razis, AFA; Sharifi-Rad, J; Sharopov, F; Sytar, O; Ydyrys, A | 1 |
| Baird, JK; Berni, A; Budiman, W; Cedar, E; Chand, K; Crenna-Darusallam, C; Duparc, S; Ekawati, LL; Elyazar, I; Fernando, D; Fletcher, K; Goyal, N; Green, JA; Instiaty, I; Jones, S; Kleim, JP; Lardo, S; Martin, A; Noviyanti, R; Prasetya, CB; Rolfe, K; Santy, YW; Satyagraha, AW; Sharma, H; Soebandrio, A; Subekti, D; Sutanto, I; Tan, LK; Taylor, M | 1 |
| Bi, D; Huang, X; Lan, Z; Lin, J; Lin, L; Lu, Y; Luo, S; Luo, X; Tang, X | 1 |
| Chotivanich, K; Dondorp, AM; Hanboonkunupakarn, B; Kobylinski, KC; Kümpornsin, K; Lee, MCS; Lek, D; Sattabongkot, J; Tarning, J; Tipthara, P; Tripura, R; White, NJ; Yipsirimetee, A | 1 |
| Aroffu, M; Fernàndez-Busquets, X; Fulgheri, F; Manca, ML; Manconi, M; Nacher, A; Peris, JE; Ramírez, M; Román-Álamo, L; Usach, I | 1 |
| Alam, MS; Faiz, A; Haldar, K; Haque, R; Islam, MN; Khan, WA; Koepfli, C; Lobo, NF; Phru, CS | 1 |
| Balta, VA; Ma, W; Pan, W; Rimer, JD; Sullivan, DJ; Vekilov, PG | 1 |
| Nabi, N; Saffeullah, P; Singh, S | 1 |
| Buncherd, H; Imwong, M; Jitueakul, S; Sanmoung, W; Sawangjaroen, N; Thanapongpichat, S; Tun, AW | 1 |
| Gupta, S; Jain, R; Kalam Najmi, A; Kumar, P; Maurya, P; Munjal, A; Shafi, S; Shoaib, R; Singh, S | 1 |
| Asua, V; Bailey, JA; Conrad, MD; Cooper, RA; Crudale, RM; Dorsey, G; Garg, S; Giesbrecht, D; Kamya, MR; Katairo, T; Legac, J; Namuganga, JF; Niaré, K; Nsobya, SL; Rosenthal, PJ; Smith, S; Tumwebaze, PK | 1 |
| Dellicour, S; Gutman, JR; Hill, J; Ochodo, E; Osoro, CB; Ter Kuile, F; Young, T | 1 |
| Abugri, J; Amon, D; Aniweh, Y; Ansah, F; Ashitei, S; Awandare, GA; Ayeke, D; Binka, FN; Boyetey, MB; Chirawurah, JD; Dinko, B; Kornu, VE; Kweku, M; Laryea, R; Nyame, K; Opoku, N; Owusu, R; Owusu-Appiah, C; Razak, N; Sutherland, CJ | 1 |
| Greenwood, B | 1 |
| D'Alessandro, U; Dabira, ED; Diakite, H; Djimde, M; Dorlo, TP; Erhart, A; González, R; Kabore, B; Kayentao, K; Keita, M; Macuacua, S; Menendez, C; Mens, P; Muhindo, HM; Piqueras, M; Sagara, I; Schallig, H; Sevene, E; Tinto, H; Traore, M; Tshiongo, JK; Vala, A | 1 |
| Acharya, S; Arnold, L; Chico, RM; Gore-Langton, GR; Lufele, E; Moore, BR; Price, RN; Rogerson, SJ; Ter Kuile, FO; Thriemer, K; Unger, HW; van Eijk, AM; Wu, C | 1 |
| Amaratunga, C; Boon, WPC; Cao, VAT; de Haan, F; Dondorp, AM; Le Quyen, D; Moors, EHM; Nguyen, TQ | 1 |
| Nath, A; Sharma, A; Singh, SK; Sundaram, S | 1 |
| Capuano, R; Di Natale, C; Pain, A; Stead, Z | 1 |
| Aubouy, A; Bourdy, G; Chassagne, F; Deharo, E; Elliott, E; Lamxay, V; Manithip, C; Souvanasy, O; Sydara, K; Sythamala, P; Torres, JA | 1 |
| Bienvenu, AL; Bonnot, G; Kouakou, YI; Lavoignat, A; Leboucher, G; Picot, S; Tod, M | 1 |
| Azad, CS; Nainwal, LM; Narula, AK | 1 |
| Ayong, L; Belle Ebanda Kedi, P; Eboumbou Moukoko, CE; Eya'ane Meva, F; Kojom Foko, LP; Lehman, LG; Ngaha Njila, MI; Ntoumba, AA | 1 |
| Adebowale, AS; Ajayi, IO; Ajumobi, O; Idris, S; Nwankwo, L; Nwokoro, U; Obi, IF; Olorukooba, A; Sabitu, K; Usman, R | 1 |
| Gao, F; Kong, F; Sun, Z; Xiao, J | 1 |
| Ariey, F; Clain, J; Duval, R; Ménard, R; Talman, AM | 1 |
| Abuaku, B; Ahorlu, CS; Amambua-Ngwa, A; Enos, JY; Koram, KA; Mensah, BA; Merle, CSC; Ndong, IC; Nyarko, A; Okyere, D | 1 |
| Aweeka, F; Huang, L; Hughes, E; Kajubi, R; Mwebaza, N; Mwima, MW; Nguyen, V; Nyunt, MM; Orukan, F; Parikh, S | 1 |
| Chaudhary, S; Tiwari, MK | 1 |
| Assebe, LF; Jbaily, A; Johansson, KA; Kwete, XJ; Liu, L; Norheim, OF; Tolla, MT; Verguet, S; Wang, D | 1 |
| D'Hoore, W; Kiguba, R; Kirabira, E; Manirakiza, L; Mukonzo, J; Nabirye, L; Ndagije, HB; Olsson, S; Speybroeck, N; Spinewine, A; Sserwanga, A | 1 |
| Desrosiers, MR; Mittelman, A; Weathers, PJ | 1 |
| Adeoti, O; Afonne, C; Ajayi, IO; Falade, CO; Gomes, M; Jegede, AS; Oshiname, FO; Spiegelman, D | 1 |
| Brown, AC; Guler, JL; Moore, CC | 1 |
| Kam, MYY; Yap, WSP | 1 |
| Agins, BD; Chung, A; Eliades, MJ; Gosling, R; Ikeda, DJ; Murungu, J | 1 |
| Bihoun, B; Derra, K; Kazienga, A; Nakanabo-Diallo, S; Pagnoni, F; Rouamba, E; Rouamba, T; Samadoulougou-Kirakoya, F; Sondo, P; Sorgho, H; Tarnagda, Z; Tinto, H; Valea, I | 1 |
| Bardají, A; Clark, R; González, R; Leke, RGF; Menendez, C; Pons-Duran, C | 1 |
| Higgins, CR; Ippolito, MM; Jackson, KD; Kobayashi, T; Laing, SK; Mwila, C; Ozawa, S; Sylvia, S | 1 |
| Jiang, T; Liao, F; Ma, N; Tu, Y; Zhang, Z | 1 |
| Dai, Y; Dong, X; Guo, Y; Wang, J; Zhang, R | 1 |
| Rocamora, F; Winzeler, EA | 1 |
| Ashley, EA; Poespoprodjo, JR | 1 |
| Adeniyi, OM; Ajibaye, O; Aremu, OI; Asogwa, N; Babamale, OA; Fakayode, O; Fatoba, IM; Iyiola, OA; Omotesho, OB; Opeyemi, OA; Salawu, KM; Shittu, O | 1 |
| He, Y; Li, Y; Liu, Q; Shen, S; Wang, J; Wong, YK; Yang, J; Zhang, J; Zhang, X; Zhong, T | 1 |
| Naing, C; Tanner, M; Whittaker, MA | 1 |
| Ayodo, G; Hamre, KES; Hodges, JS; John, CC | 1 |
| Ao, Z; Han, D; Hu, N; Hu, X; Liao, F; Zhang, Q | 1 |
| Barrett, MP; Hughes, KR; Rennie, MT; Simwela, NV; Waters, AP | 1 |
| Kanyal, A; Karmodiya, K; Lopez-Rubio, JJ; Rawat, M; Sahasrabudhe, A; Vembar, SS | 1 |
| Beteck, RM; Legoabe, LJ; Patel, OPS | 1 |
| Ahanhanzo, CD; Amouh, TS; Ekoye, SM; Guiguemdé, TR; Sombié, I | 1 |
| Das, S; Hati, AK; Kar, A; Mandal, S; Manna, S; Saha, B | 1 |
| Awasthi, SK; Sharma, B; Singh, AK; Singh, P | 1 |
| Kimata-Ariga, Y; Morihisa, R | 1 |
| Bustos, D; Lin, K; Myint, MK; Rasmussen, C; Ringwald, P; Thi, A | 1 |
| Khin, HSS; Thein, ST; Thi, A | 1 |
| Chinnakali, P; Nwe, TW; Oo, T; Shah, S; Thi, A; van Griensven, J; Wai, KT; Zhou, S | 1 |
| Lek, D; Phok, S | 1 |
| Adhin, MR; Barnwell, JW; Chenet, SM; Huber, CS; Kelley, J; Lucchi, N; Macedo de Oliveira, A; Okoth, SA; Udhayakumar, V; Vreden, S | 1 |
| Goodman, C; Hanson, K; Tougher, S | 1 |
| Lun, ZR; Meshnick, SR; Wang, J; Xu, C | 1 |
| D'Alessandro, U; Djimdé, AA; Dorsey, G; Karema, C; Mårtensson, AA; Ndiaye, JL; Olliaro, PL; Zwang, J | 1 |
| Diagne, N; Diene Sarr, F; Doucoure, S; Faye, N; Gaudart, J; Raoult, D; Sokhna, C; Tall, A; Wotodjo, AN | 1 |
| Alokozai, A; Baktash, SH; Buhler, C; Cundill, B; Hasanzai, A; Laurent, B; Leslie, T; Mayan, I; Mikhail, A; Mohammed, N; Rahimi, HU; Rowland, M; Whitty, CJM; Willey, B; Wood, M | 1 |
| D'Alessandro, U; Dias, S; Donegan, S; Tudur Smith, C; Welton, NJ | 1 |
| Bagire, PG; Daddy, NB; Kalisya, LM; Towler, MJ; Watt, RL; Weathers, PJ | 1 |
| Burrows, JN; Manyando, C; Phillips, MA; van Huijsduijnen, RH; Van Voorhis, WC; Wells, TNC | 1 |
| Brooker, SJ; Chatsika, H; Halliday, KE; Mathanga, DP; Mphwatiwa, T; Mtali, A; Nguluwe, P; Okello, G; Roschnik, N; Witek-McManus, S | 1 |
| Al-Mafazy, AW; Ali, AS; Amier, HH; Garimo, IA; Kafuko, JM; Khatib, B; Mkali, H; Msellem, M; Ngondi, JM; Paxton, LA; Ramsan, MM; Reithinger, R; Shija, J; Thawer, NG | 1 |
| Danafar, H; Keramati, M; Kheiri Manjili, H; Malvandi, H; Ramazani, A | 1 |
| Audureau, E; Davis, B; Ladner, J; Saba, J | 1 |
| Blessborn, D; Day, NPJ; Kaewkhao, K; Song, L; Tarning, J; White, NJ | 1 |
| Gazin, P; Muila, M | 1 |
| Bergstrand, M; Dondorp, AM; Hanpithakpong, W; Karlsson, MO; Lim, P; Lohy Das, J; Nosten, F; Phyo, AP; Ringwald, P; Tarning, J; White, NJ | 1 |
| Canavati, SE; Habib, N; Ly, P; McGinn, C; Nguon, C; Quintero, CE; Richards, JS; Thwing, J; Top-Samphor, N; Vinjamuri, SB | 1 |
| Affane, B; Chakir, I; Jambou, R; Said, AI | 1 |
| Agaba, B; Kasasa, S; Kissa, J; Makumbi, F; Nambuusi, B; Ssempiira, J; Vounatsou, P | 1 |
| Çavuş, İ; Kaya, T; Nuraydın, A; Özbilgin, A | 1 |
| Achidi, EA; Amambua-Ngwa, A; Amato, R; Anchang-Kimbi, JK; Apinjoh, TO; Chi, HF; Djimde, A; Fon, EM; Jacob, C; Kwiatkowski, D; Miotto, O; Mugri, RN; Nyingchu, RV; Tangoh, DA; Tata, RB | 1 |
| Gopinath, D; Hongvangthong, B; Kongmanivong, P; Phommixay, S; Sichanthongthip, O; Simmalavong, N; Sintasath, DM | 1 |
| Jaafari, A; Mouse, HA; Oukerrou, MA; Tilaoui, M; Zyad, A | 1 |
| Clarke, SE; Hansen, KS; Lal, S; Magnussen, P; Mbonye, AK | 1 |
| Abwao, E; Ejersa, W; Kiptui, R; Memusi, D; Musuva, A | 1 |
| Achan, J; Byakika-Kibwika, P; Karera-Gonahasa, C; Kiragga, AN; Kiwanuka, N; Lamorde, M; Mayanja-Kizza, H; Merry, C; Nsobya, S; Talisuna, AO | 1 |
| Betson, M; Clifford, S; Kabatereine, NB; Stanton, M; Stothard, JR | 1 |
| Rogerson, SJ | 1 |
| Du, Y; Ismail, M; Li, X; Ling, L; Yao, C | 1 |
| Arnold, F; Bruxvoort, K; Festo, C; Goodman, C; Hanson, K; Johanes, B; Kalolella, A; Mann, A; Ren, R; Taylor, M; Thomson, R; Tougher, S; Willey, B; Ye, Y | 1 |
| Chikodzore, R; Dube, B; Mberikunashe, J; Muchena, G; Murugasampillay, S; Pasipamire, J | 1 |
| Ashley, EA; Pyae Phyo, A; Woodrow, CJ | 1 |
| Kasasa, S; Kissa, J; Kyozira, C; Makumbi, F; Mukooyo, E; Nambuusi, B; Opigo, J; Rutazaana, D; Ssempiira, J; Vounatsou, P | 1 |
| Gong, M; Li, J; Wang, M; Zhang, C | 1 |
| César, IC; Fernandes, C; Pianetti, GA; Ricoy, LBM; Rivelli, GG | 1 |
| Brewer, JM; Lee, RS; Waters, AP | 1 |
| Alexander, ND; Chandramohan, D; Clarke, SE; Hansen, KS; Lal, S; Magnussen, P; Ndyomugenyi, R; Paintain, L | 1 |
| Ashley, EA; Phyo, AP | 1 |
| Boni, MF; Farrar, J; Giang, DDH; Goldlust, SM; Grenfell, BT; Hien, TT; Nguyen, TD; Thang, ND; Thanh, NV; Thuan, PD; Thwaites, GE | 1 |
| Kamara, ARY; Menard, D; Sahr, F; Samai, M; Smith, SJ; Swaray, AS; Warsame, M | 1 |
| Anyanti, J; BongosIkwue, E; Ezire, O; Isiguzo, C; Nwokolo, E; Oyibo, WA; Raji, M; Udoye, I; Ujuju, C | 1 |
| Kipkoech, J; Laktabai, J; Maffioli, E; Menya, D; Mohanan, M; Platt, A; Prudhomme O'Meara, W; Saran, I; Turner, EL | 1 |
| Maxmen, A | 5 |
| Emami, J; Sadeghi, H; Yousefian, H | 1 |
| Afrane, YA; Boakye, MDS; Oluoch, E; Owek, CJ; Wachira, J | 1 |
| Jat, JL; Karnatak, M; Kumari, A; Shankar, R; Sharma, S; Shrivastava, R; Singh, D; Verma, VP; Yadav, D | 1 |
| Herbas, MS; Kume, A; Suzuki, H | 1 |
| Awor, P; Evans, DR; Higgins, CR; Laing, SK; Ozawa, S | 1 |
| Beavogui, AH; Borghini-Fuhrer, I; Djimdé, AA; Duparc, S; Felices, M; Funck-Brentano, C; Khan, Y; Ouedraogo, JB; Ouologuem, N; Sagara, I; Sirima, SB; Soulama, I; Voiriot, P | 1 |
| Witvorapong, N; Yakubu, KY | 1 |
| Bai, F; Bai, G; Chen, M; Gou, Y; Liao, Z; Zhang, F; Zhang, T | 1 |
| Benoit-Vical, F; Liu, Y; Meunier, B; Robert, A | 1 |
| Ampofo, G; Arango, D; Buyze, J; D'Alessandro, U; Hachizovu, S; Kabuya, JB; Mulenga, M; Mwapasa, V; Nambozi, M; Ravinetto, R; Tagbor, H; Tahita, MC; Thriemer, K; Tinto, H; Traoré, M; Valea, I; van Geertruyden, JP | 1 |
| Jiang, T; Krishna, S; Liao, FL; Tu, Y; Wang, J; Xu, C | 1 |
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| Ahorlu, CS; Amambua-Ngwa, A; Enos, JY; Koram, KA; Merle, CSC; Ndong, IC; Nyarko, A; Okyere, D | 1 |
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| Bojang, K; D'Alessandro, U; Okebe, J | 1 |
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| Arnold, F; Bruxvoort, K; Cairns, M; Festo, C; Goodman, C; Hanson, K; Johanes, B; Kachur, SP; Kalolella, A; Kleinschmidt, I; Mann, A; Nchimbi, H; Ren, R; Taylor, M; Thomson, R; Tougher, S; Willey, B; Ye, Y | 1 |
| Chen, WQ; Deng, Y; Liu, Y; Qian, D; Zhang, HW; Zhao, XD; Zhou, RM | 1 |
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| Ali, D; Brooker, SJ; Chimuna, T; Halliday, KE; Mathanga, DP; Mazinga, C; Melody, D; Mtali, A; Mwenda, R; Ndau, S; Phondiwa, E; Roschnik, N; Sande, J; Verney, A; Witek-McManus, S | 1 |
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| Afonne, C; Ajayi, IO; Falade, CO; Jegede, AS; Nsungwa-Sabiiti, J; Oshiname, FO; Sanou, AK; Sermé, L; Siribié, M | 1 |
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154 review(s) available for artemisinin and Malaria
| Article | Year |
|---|---|
Current progress in antimalarial pharmacotherapy and multi-target drug discovery.
Topics: Animals; Antimalarials; Artemisinins; Drug Discovery; Drug Resistance; Humans; Malaria; Molecular Structure; Paclitaxel; Quinolines | 2020 |
Drug-induced hypersensitivity to artemisinin-based therapies for malaria.
Topics: Antimalarials; Artemisinins; Drug Therapy, Combination; Humans; Hypersensitivity; Malaria; Malaria, Falciparum; Plasmodium falciparum | 2022 |
Pediatric Malaria: Global and North American Perspectives.
Topics: Acute Kidney Injury; Anemia; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Child; Child, Preschool; Female; Global Health; Humans; Infant; Malaria; Male; North America; Plasmodium; Respiratory Distress Syndrome; Travel | 2022 |
Extraction, Isolation and Characterization of Bioactive Compounds from
Topics: Artemisia annua; Artemisinins; Humans; Malaria; Phytochemicals; Plants, Medicinal | 2021 |
New Insights into Artesunate as a Pleiotropic Regulator of Innate and Adaptive Immune Cells.
Topics: Adaptive Immunity; Animals; Antimalarials; Artemisinins; Artesunate; Humans; Immune System Diseases; Immunity, Innate; Immunomodulation; Malaria | 2022 |
Safety of treating malaria with artemisinin-based combination therapy in the first trimester of pregnancy.
Topics: Antimalarials; Artemisinins; Female; Humans; Malaria; Pregnancy; Pregnancy Trimester, First | 2022 |
Bridging the Gap in Malaria Parasite Resistance, Current Interventions, and the Way Forward from in Silico Perspective: A Review.
Topics: Animals; Antimalarials; Artemisinins; Humans; Malaria; Parasites; Plasmodium falciparum | 2022 |
Pregnancy outcomes after first-trimester treatment with artemisinin derivatives versus non-artemisinin antimalarials: a systematic review and individual patient data meta-analysis.
Topics: Abortion, Spontaneous; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Drug Combinations; Ethanolamines; Female; Humans; Malaria; Malaria, Falciparum; Pregnancy; Pregnancy Outcome; Pregnancy Trimester, First; Prospective Studies; Quinine; Stillbirth | 2023 |
A comprehensive overview of Artemisinin and its derivatives as anticancer agents.
Topics: Antimalarials; Antineoplastic Agents; Artemisinins; Humans; Malaria | 2023 |
Therapeutical Utilization and Repurposing of Artemisinin and Its Derivatives: A Narrative Review.
Topics: Antimalarials; Artemisinins; Drug Repositioning; Folic Acid Antagonists; Humans; Malaria | 2023 |
Medicinal and mechanistic overview of artemisinin in the treatment of human diseases.
Topics: Antimalarials; Artemisinins; Humans; Malaria | 2023 |
Bangladesh in the era of malaria elimination.
Topics: Antimalarials; Bangladesh; Drug Resistance; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum | 2023 |
An updated review on distribution, biosynthesis and pharmacological effects of artemisinin: A wonder drug.
Topics: Antimalarials; Artemisia; Artemisia annua; Artemisinins; COVID-19; Malaria | 2023 |
The effect and control of malaria in pregnancy and lactating women in the Asia-Pacific region.
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Asia; Female; Humans; Lactation; Malaria; Malaria, Falciparum; Pregnancy | 2023 |
Exploring the feasibility of introducing triple artemisinin-based combination therapy in the malaria treatment policy in Vietnam.
Topics: Antimalarials; Artemisinins; Drug Therapy, Combination; Feasibility Studies; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum; Policy; Vietnam | 2023 |
Bio Prospecting of Endophytes and PGPRs in Artemisinin Production for the Socio-economic Advancement.
Topics: Artemisia annua; Artemisinins; Endophytes; Malaria; Plants, Medicinal; Socioeconomic Factors | 2023 |
Systematic review of artesunate pharmacokinetics: Implication for treatment of resistant malaria.
Topics: Administration, Intravenous; Administration, Oral; Antimalarials; Artemisinins; Artesunate; Asia, Southeastern; Drug Monitoring; Drug Resistance; Humans; Malaria; Malaria, Falciparum | 2019 |
New dimensions in the field of antimalarial research against malaria resurgence.
Topics: Animals; Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria; Plasmodium falciparum | 2019 |
A systematic review on anti-malarial drug discovery and antiplasmodial potential of green synthesis mediated metal nanoparticles: overview, challenges and future perspectives.
Topics: Antimalarials; Artemisinins; Drug Discovery; Malaria; Metal Nanoparticles; Plant Extracts; Plant Leaves; Plasmodium falciparum; Silver | 2019 |
Current scenario of ferrocene-containing hybrids for antimalarial activity.
Topics: Antimalarials; Artemisinins; Ferrous Compounds; Humans; Malaria; Metallocenes; Molecular Structure; Parasitic Sensitivity Tests; Peroxides; Plasmodium falciparum; Quinolines | 2020 |
Artemisinin Bioactivity and Resistance in Malaria Parasites.
Topics: Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria; Models, Biological; Mutation; Plasmodium; Protozoan Proteins | 2019 |
Artemisinin-derived antimalarial endoperoxides from bench-side to bed-side: Chronological advancements and future challenges.
Topics: Animals; Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria; Peroxides; Translational Research, Biomedical | 2020 |
An oxidatively stressful situation: a case of
Topics: Antimalarials; Artemisia annua; Artemisinins; Biotechnology; Humans; Malaria; Oxidative Stress | 2020 |
Systematic review of artemisinin embryotoxicity in animals: Implications for malaria control in human pregnancy.
Topics: Abnormalities, Drug-Induced; Animals; Antimalarials; Artemisinins; Embryo, Mammalian; Female; Humans; Malaria; Pregnancy; Pregnancy Complications, Parasitic | 2020 |
The birth of artemisinin.
Topics: Animals; Antimalarials; Artemisia annua; Artemisinins; Humans; Malaria; Molecular Structure; Plasmodium; Structure-Activity Relationship | 2020 |
Genomic Approaches to Drug Resistance in Malaria.
Topics: Alleles; Antiprotozoal Agents; Artemisinins; Drug Resistance; Genomics; Humans; Malaria; Phenotype; Plasmodium falciparum; Protozoan Proteins | 2020 |
Treatment and prevention of malaria in children.
Topics: Antimalarials; Artemisinins; Child; Child Welfare; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Female; Humans; Malaria; Malaria Vaccines; Male; Seasons; Vaccination | 2020 |
Advances in the research on the targets of anti-malaria actions of artemisinin.
Topics: Animals; Antimalarials; Antineoplastic Agents; Artemisinins; Drug Repositioning; Host-Parasite Interactions; Humans; Malaria; Neoplasms; Plasmodium | 2020 |
Multisectoral Approach to Support Use of Insecticide-Treated Net for Malaria Prevention Among Mobile and Migrant Populations in Myanmar: A Systematic Review.
Topics: Artemisinins; Communicable Disease Control; Female; Health Knowledge, Attitudes, Practice; Humans; Insecticide Resistance; Insecticide-Treated Bednets; Intersectoral Collaboration; Malaria; Male; Myanmar; Transients and Migrants | 2020 |
Exploration of artemisinin derivatives and synthetic peroxides in antimalarial drug discovery research.
Topics: Animals; Antimalarials; Artemisinins; Drug Discovery; Humans; Malaria; Peroxides; Plasmodium falciparum | 2021 |
Advancement of chimeric hybrid drugs to cure malaria infection: An overview with special emphasis on endoperoxide pharmacophores.
Topics: Acridines; Antimalarials; Artemisinins; Drug Design; Half-Life; Humans; Malaria; Quinolines; Tetraoxanes | 2021 |
Unpacking 'Artemisinin Resistance'.
Topics: Animals; Anti-Infective Agents; Antimalarials; Artemisinins; Drug Resistance; Drug Therapy, Combination; Humans; Malaria | 2017 |
Animal Embryotoxicity Studies of Key Non-Artemisinin Antimalarials and Use in Women in the First Trimester.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Drug Combinations; Female; Humans; Malaria; Malaria, Falciparum; Naphthyridines; Pregnancy; Pregnancy Trimester, First; Pyrimethamine; Quinine; Quinolines; Rabbits; Rats; Sulfadoxine; Teratogens | 2017 |
Malaria.
Topics: Africa; Animals; Anopheles; Anti-Infective Agents; Antimalarials; Artemisinins; Child, Preschool; Drug Resistance; Female; Humans; Infant; Insecticide-Treated Bednets; Insecticides; Malaria; Male; Mosquito Control; Mosquito Vectors; Plasmodium; Plasmodium falciparum; Plasmodium vivax | 2017 |
Control of malaria in the Comoro Islands over the past century.
Topics: Antimalarials; Artemisinins; Communicable Disease Control; Comoros; Drug Therapy, Combination; Humans; Malaria | 2017 |
More insights into the pharmacological effects of artemisinin.
Topics: Anti-Infective Agents; Artemisinins; Humans; Malaria | 2018 |
Management of malaria in pregnancy.
Topics: Adult; Antimalarials; Artemisinins; Female; Humans; Malaria; Pregnancy; Pregnancy Complications, Infectious; Quinine | 2017 |
A review of progress towards sub-national malaria elimination in Matabeleland South Province, Zimbabwe (2011-2015): a qualitative study.
Topics: Antimalarials; Artemisinins; Case Management; Disease Eradication; Humans; Incidence; Insect Control; Malaria; Mosquito Vectors; Primaquine; Zimbabwe | 2018 |
Malaria.
Topics: Antimalarials; Artemisinins; Disease Eradication; Drug Discovery; Drug Resistance, Microbial; Humans; Insecticide Resistance; Insecticide-Treated Bednets; Malaria; Malaria Vaccines; Mosquito Control; Protective Factors; Risk Factors | 2018 |
Drugs in Development for Malaria.
Topics: Aminoquinolines; Antimalarials; Artemisinins; Drug Discovery; Drug Resistance, Multiple; Ferrous Compounds; Humans; Imidazoles; Lumefantrine; Malaria; Metallocenes; Piperazines; Signal Transduction; Treatment Outcome | 2018 |
Current scenario of artemisinin and its analogues for antimalarial activity.
Topics: Antimalarials; Artemisinins; Humans; Malaria; Plasmodium | 2019 |
Potential of Vitamin E Deficiency, Induced by Inhibition of α-Tocopherol Efflux, in Murine Malaria Infection.
Topics: alpha-Tocopherol; Animals; Antimalarials; Artemisinins; Carrier Proteins; Cytokines; Malaria; Oxidative Stress; Vitamin E; Vitamin E Deficiency | 2018 |
Small Molecules: The Past or the Future in Drug Innovation?
Topics: Alzheimer Disease; Antimalarials; Artemisinins; Copper; Drug Design; Heme; Humans; Iron; Malaria; Schistosomiasis | 2019 |
The genomic architecture of antimalarial drug resistance.
Topics: Aminoquinolines; Anti-Bacterial Agents; Antimalarials; Artemisinins; Atovaquone; Drug Resistance; Drug Resistance, Multiple; Folic Acid Antagonists; Humans; Malaria; Plasmodium falciparum; Plasmodium vivax; Quinine | 2019 |
Artemisinin and its derivatives; ancient tradition inspiring the latest therapeutic approaches against malaria.
Topics: Antimalarials; Artemisia; Artemisinins; Humans; Malaria; Medicine, Chinese Traditional; Molecular Structure | 2019 |
Early parasitological response following artemisinin-containing regimens: a critical review of the literature.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Monitoring; Humans; Malaria; Parasite Load; Parasitemia; Time Factors; Treatment Outcome; Young Adult | 2013 |
Role of traditional antimalarial plants in the battle against the global malaria burden.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Global Health; Humans; Malaria; Medicine, Traditional; Plant Components, Aerial; Plant Roots; Plants, Medicinal; Plasmodium; Quinine | 2013 |
Malaria.
Topics: Africa South of the Sahara; Amodiaquine; Animals; Anopheles; Antimalarials; Artemisinins; Artesunate; Asia, Southeastern; Chloroquine; Drug Administration Schedule; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Humans; Insecticide-Treated Bednets; Insecticides; Malaria; Malaria Vaccines; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Pregnancy; Pregnancy Complications, Infectious; Primary Prevention; Pyrimethamine; Quinine; Quinolines; Seasons; Sulfadoxine | 2014 |
Malaria and artemisinin derivatives: an updated review.
Topics: Animals; Antimalarials; Artemisinins; Chemistry, Pharmaceutical; Drug Combinations; Drug Resistance; Humans; Malaria | 2013 |
Malaria situation in the Greater Mekong Subregion.
Topics: Antimalarials; Artemisinins; Asia, Southeastern; Drug Resistance; Humans; Incidence; Malaria | 2013 |
Migration and malaria.
Topics: Antimalarials; Artemisinins; Asia, Southeastern; Conservation of Natural Resources; Disasters; Drug Resistance; Economic Development; Emigration and Immigration; Humans; Malaria; Politics; Socioeconomic Factors | 2013 |
Considerations on the mechanism of action of artemisinin antimalarials: part 1--the 'carbon radical' and 'heme' hypotheses.
Topics: Animals; Antimalarials; Artemisinins; Carbon; Heme; Humans; Malaria | 2013 |
Adherence to artemisinin-based combination therapy for the treatment of malaria: a systematic review of the evidence.
Topics: Antimalarials; Artemisinins; Drug Combinations; Drug Therapy, Combination; Humans; Malaria; Medication Adherence | 2014 |
How patients take malaria treatment: a systematic review of the literature on adherence to antimalarial drugs.
Topics: Antimalarials; Artemisinins; Humans; Malaria; Patient Compliance | 2014 |
Malaria successes and challenges in Asia.
Topics: Anti-Infective Agents; Artemisinins; Asia; Disease Eradication; Drug Resistance; Humans; Incidence; Malaria; Plasmodium | 2013 |
Metabolic engineering of plants for artemisinin synthesis.
Topics: Artemisia annua; Artemisinins; Humans; Malaria; Metabolic Engineering; Plants; Synthetic Biology | 2013 |
Price subsidies increase the use of private sector ACTs: evidence from a systematic review.
Topics: Africa; Antimalarials; Artemisinins; Drug Therapy, Combination; Health Services Accessibility; Humans; Malaria; Prescription Fees; Private Sector; Rural Population; Urban Population | 2015 |
Antimalarial drug policy in India: past, present & future.
Topics: Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Humans; India; Malaria; Plasmodium falciparum | 2014 |
Use of artemisinin and its derivatives for the treatment of malaria in children.
Topics: Africa South of the Sahara; Antimalarials; Artemisinins; Child, Preschool; Drug Resistance; Humans; Infant; Infant, Newborn; Malaria | 2014 |
Artemisinin-based combination therapies and their introduction in Japan.
Topics: Anti-Infective Agents; Artemisinins; China; Drug Combinations; Humans; Malaria; Materia Medica | 2014 |
Malaria: an update on current chemotherapy.
Topics: Antimalarials; Artemisinins; Drug Discovery; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria; Plasmodium; Pregnancy | 2014 |
New insight-guided approaches to detect, cure, prevent and eliminate malaria.
Topics: Animals; Artemisinins; Culicidae; Diagnostic Techniques and Procedures; Disease Eradication; Drug Resistance; Humans; Malaria | 2015 |
Synthetic chemistry fuels interdisciplinary approaches to the production of artemisinin.
Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Drug Resistance, Microbial; Malaria; Molecular Structure; Plasmodium falciparum | 2015 |
Efficacy and safety of artemisinin combination therapy (ACT) for non-falciparum malaria: a systematic review.
Topics: Antimalarials; Artemisinins; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Humans; Malaria; Treatment Outcome | 2014 |
Artemisinin-based combination therapy in the treatment of uncomplicated malaria: review of recent regulatory experience at the European Medicines Agency.
Topics: Antimalarials; Artemisinins; Drug and Narcotic Control; Drug Therapy, Combination; Europe; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum | 2015 |
Towards subsidized malaria rapid diagnostic tests. Lessons learned from programmes to subsidise artemisinin-based combination therapies in the private sector: a review.
Topics: Antimalarials; Artemisinins; Diagnostic Tests, Routine; Humans; Inappropriate Prescribing; Malaria; Private Sector | 2016 |
Antimalarial drug resistance in Africa: key lessons for the future.
Topics: Africa; Animals; Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Forecasting; Humans; Malaria; Pyrimethamine; Sulfadoxine | 2015 |
Assessing key assumptions of network meta-analysis: a review of methods.
Topics: Antimalarials; Artemisinins; Biostatistics; Clinical Trials as Topic; Humans; Malaria; Meta-Analysis as Topic; Models, Statistical; Treatment Outcome | 2013 |
Artemisinin resistance, some facts and opinions.
Topics: Antimalarials; Artemisinins; Asia, Southeastern; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Plasmodium | 2015 |
The Case for Development of 11-Aza-artemisinins for Malaria.
Topics: Administration, Oral; Animals; Antimalarials; Artemisinins; Drug Design; Humans; Malaria; Mice; Molecular Structure | 2015 |
Antimalarial Drug Resistance: Literature Review and Activities and Findings of the ICEMR Network.
Topics: Antimalarials; Artemisinins; Biomedical Research; Drug Resistance; Humans; International Cooperation; Malaria; Plasmodium falciparum; Plasmodium vivax | 2015 |
Use of quantitative pharmacology tools to improve malaria treatments.
Topics: Animals; Antimalarials; Artemisinins; Child; Drug Design; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria; Pregnancy | 2016 |
Subsidising artemisinin-based combination therapy in the private retail sector.
Topics: Africa, Eastern; Antimalarials; Artemisinins; Child, Preschool; Drug Costs; Financial Support; Humans; Infant; Malaria; Private Sector; Program Evaluation; Randomized Controlled Trials as Topic | 2016 |
Artemisinin-Derived Dimers: Potent Antimalarial and Anticancer Agents.
Topics: Animals; Antimalarials; Antineoplastic Agents, Phytogenic; Artemisinins; Dimerization; Heterocyclic Compounds; Humans; Malaria; Molecular Conformation; Neoplasms | 2016 |
Honoring antiparasitics: The 2015 Nobel Prize in Physiology or Medicine.
Topics: Animals; Antiparasitic Agents; Artemisinins; Communicable Diseases; Humans; Malaria; Nobel Prize; Parasitic Diseases | 2016 |
Artemisinin-A Gift from Traditional Chinese Medicine to the World (Nobel Lecture).
Topics: Antimalarials; Artemisinins; Humans; Malaria; Medicine, Chinese Traditional | 2016 |
The Safety of Artemisinin Derivatives for the Treatment of Malaria in the 2nd or 3rd Trimester of Pregnancy: A Systematic Review and Meta-Analysis.
Topics: Abortion, Spontaneous; Antimalarials; Artemisinins; Cohort Studies; Female; Humans; Malaria; Pregnancy; Pregnancy Complications, Parasitic; Pregnancy Outcome; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Quinine; Randomized Controlled Trials as Topic | 2016 |
Genome-Wide Association Studies of Drug-Resistance Determinants.
Topics: Antimalarials; Artemisinins; Drug Resistance; Genetics, Population; Genome-Wide Association Study; Humans; Malaria; Plasmodium falciparum | 2017 |
New medicines for tropical diseases in pregnancy: catch-22.
Topics: Anti-Infective Agents; Artemisinins; Female; Humans; Malaria; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Complications, Parasitic; Tropical Climate; Tropical Medicine | 2008 |
Artemisinin derivatives versus quinine in treating severe malaria in children: a systematic review.
Topics: Adolescent; Antimalarials; Artemisinins; Asia, Southeastern; Child; Child, Preschool; Clinical Trials as Topic; Humans; Infant; Infant, Newborn; Malaria; Quinine; Treatment Outcome | 2008 |
Recent advances in artemisinin production through heterologous expression.
Topics: Antimalarials; Artemisia annua; Artemisinins; Biosynthetic Pathways; Escherichia coli; Genetic Engineering; Malaria; Plants, Genetically Modified; Saccharomyces cerevisiae | 2008 |
Deployment of ACT antimalarials for treatment of malaria: challenges and opportunities.
Topics: Animals; Antimalarials; Artemisinins; Drug Therapy, Combination; Health Policy; Health Services Accessibility; Humans; Malaria; Plasmodium; Poverty Areas; Treatment Outcome | 2008 |
The role of anti-malarial drugs in eliminating malaria.
Topics: Aminoquinolines; Animals; Antimalarials; Artemisinins; Drug Therapy, Combination; Health Policy; Humans; Malaria; Plasmodium; Primaquine; Treatment Outcome | 2008 |
Application of pharmacogenomics to malaria: a holistic approach for successful chemotherapy.
Topics: Animals; Antimalarials; Artemisinins; Cost of Illness; Culicidae; Drug Resistance; Drug Therapy, Combination; Holistic Health; Humans; Insecticides; Malaria; Pharmacogenetics; Plasmodium falciparum; Polymorphism, Genetic; Quinine | 2009 |
Artemisinin-based combination therapy for treating uncomplicated malaria.
Topics: Antimalarials; Artemisinins; Artesunate; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Parasitemia; Pyrimethamine; Quinolines; Randomized Controlled Trials as Topic; Sulfadoxine | 2009 |
Global resistance surveillance: ensuring antimalarial efficacy in the future.
Topics: Antimalarials; Artemisinins; Drug Combinations; Drug Resistance; Humans; Malaria; Population Surveillance; Time Factors; Treatment Outcome | 2009 |
Pharmacokinetic and toxicological profile of artemisinin compounds: an update.
Topics: Animals; Antimalarials; Artemisinins; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Malaria; Molecular Structure; Neurotoxicity Syndromes; Reproduction | 2009 |
[From onions to artemisinin. Brief history of malaria chemotherapy].
Topics: Animals; Antimalarials; Artemisinins; History, 19th Century; History, 20th Century; Humans; Malaria; Medicine, Arabic; Onions; Phytotherapy; Quinine | 2009 |
[Active agents and resistance mechanisms. Medicinal Chemistry of drugs against malaria].
Topics: Animals; Anti-Bacterial Agents; Antimalarials; Artemisinins; Dihydropteroate Synthase; Folic Acid Antagonists; Humans; Malaria; Quinine | 2009 |
Do paediatric drug formulations of artemisinin combination therapies improve the treatment of children with malaria? A systematic review and meta-analysis.
Topics: Anti-Infective Agents; Artemisinins; Child; Child, Preschool; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Infant; Malaria; Patient Selection; Tablets; Treatment Outcome | 2010 |
Toxicity of the antimalarial artemisinin and its dervatives.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Clinical Trials as Topic; Developing Countries; Dogs; Drug Administration Routes; Drug-Related Side Effects and Adverse Reactions; Humans; Malaria; Rabbits; Rats; Sesquiterpenes | 2010 |
[Subsidized artemisinin based combination treatments for Africa].
Topics: Africa; Anti-Infective Agents; Artemisinins; Drug Resistance; Drug Therapy, Combination; Humans; International Agencies; Malaria | 2010 |
Antimalarial drugs: modes of action and mechanisms of parasite resistance.
Topics: Antimalarials; Artemisinins; Atovaquone; Drug Resistance; Folic Acid Antagonists; Humans; Malaria; Plasmodium falciparum; Quinolines | 2010 |
Trioxaquines: hybrid molecules for the treatment of malaria.
Topics: Aminoquinolines; Animals; Antimalarials; Artemisinins; Drug Design; Drug Resistance; Erythrocytes; Humans; Malaria | 2010 |
The pharmacokinetic evaluation of artemisinin drugs for the treatment of malaria in paediatric populations.
Topics: Antimalarials; Artemisinins; Child; Clinical Trials as Topic; Combined Modality Therapy; Dose-Response Relationship, Drug; Drug Resistance; Evaluation Studies as Topic; Humans; Malaria; Pediatrics; Protein-Energy Malnutrition | 2011 |
Genetic analysis in mice identifies cysteamine as a novel partner for artemisinin in the treatment of malaria.
Topics: Amidohydrolases; Animals; Artemisinins; Cysteamine; Disease Models, Animal; Drug Therapy, Combination; GPI-Linked Proteins; Humans; Malaria; Mice; Plasmodium | 2011 |
Medicinal chemistry perspectives of trioxanes and tetraoxanes.
Topics: Animals; Antimalarials; Antineoplastic Agents; Artemisia; Artemisinins; Heterocyclic Compounds; Humans; Malaria; Neoplasms; Plasmodium; Tetraoxanes | 2011 |
Pharmacokinetics of antimalarials in pregnancy: a systematic review.
Topics: Anti-Bacterial Agents; Antimalarials; Artemisinins; Atovaquone; Chloroquine; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Lumefantrine; Malaria; Mefloquine; Pregnancy; Pregnancy Complications, Parasitic; Proguanil; Pyrimethamine; Quinine; Sulfadoxine | 2011 |
Malaria drug resistance: new observations and developments.
Topics: Antimalarials; Artemisinins; Asia, Southeastern; Cinchona; Drug Resistance; Haplotypes; Humans; Malaria; Plasmodium | 2011 |
Implementation research evidence uptake and use for policy-making.
Topics: Anti-Infective Agents; Artemisinins; Bangladesh; Burkina Faso; Developing Countries; Diarrhea; Evidence-Based Medicine; Health Policy; Humans; Malaria; Policy Making; Trace Elements; Translational Research, Biomedical; Zinc | 2012 |
Scaling-up malaria treatment: a review of the performance of different providers.
Topics: Adult; Antimalarials; Artemisinins; Child; Community Health Services; Developing Countries; Drug Combinations; Drug Costs; Drug Resistance; Female; Humans; Malaria; Male; Public Health; Referral and Consultation | 2012 |
Chemotherapeutic agents against malaria: what next after chloroquine?
Topics: Animals; Antimalarials; Artemisinins; Biological Factors; Chloroquine; Folic Acid Antagonists; Humans; Malaria; Protease Inhibitors; Quinine; Sesquiterpenes | 2002 |
Artemesinins for severe malaria in Africa?
Topics: Adult; Antimalarials; Artemether; Artemisia; Artemisinins; Child; Drug Evaluation; Humans; Malaria; Phytotherapy; Sesquiterpenes | 2002 |
WHO, the Global Fund, and medical malpractice in malaria treatment.
Topics: Africa; Antimalarials; Artemisinins; Child; Chloroquine; Drug Combinations; Drug Costs; Drug Resistance; Drug Therapy, Combination; Humans; International Agencies; Malaria; Malaria, Falciparum; Malpractice; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Failure; World Health Organization | 2004 |
Development of artemisinin and its structurally simplified trioxane derivatives as antimalarial drugs.
Topics: Anti-Infective Agents; Antimalarials; Artemisinins; Humans; Malaria; Sesquiterpenes; Stereoisomerism; Structure-Activity Relationship | 2004 |
Artemisinin derivatives: toxic for laboratory animals, safe for humans?
Topics: Animals; Antimalarials; Artemisinins; Dogs; Humans; Macaca mulatta; Malaria; Mice; Rats; Sesquiterpenes; Species Specificity | 2004 |
Mechanisms of in situ activation for peroxidic antimalarials.
Topics: Animals; Anti-Infective Agents; Antimalarials; Artemisia; Artemisinins; Drug Design; Free Radicals; Humans; Malaria; Oxidation-Reduction; Peroxides; Plasmodium; Sesquiterpenes | 2003 |
[Combined antimalarial therapy using artemisinin].
Topics: Amodiaquine; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Doxycycline; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Mefloquine; Plasmodium; Pyrimethamine; Quinine; Sesquiterpenes; Sulfadoxine | 2004 |
Antimalarial drug resistance, artemisinin-based combination therapy, and the contribution of modeling to elucidating policy choices.
Topics: Antimalarials; Artemisinins; Drug Resistance, Multiple; Drug Therapy, Combination; Humans; Malaria; Models, Theoretical; Sesquiterpenes | 2004 |
Malaria in endemic areas.
Topics: Antimalarials; Artemether; Artemisinins; Blood Transfusion; Chloroquine; Deferoxamine; Drug Combinations; Humans; Malaria; Malaria, Falciparum; Pyrimethamine; Quinine; Sesquiterpenes; Sulfadoxine | 2003 |
Synthetic peroxides as antimalarials.
Topics: Animals; Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria; Oxidants; Peroxides; Sesquiterpenes | 2004 |
[Review of the use of artemisinin and its derivatives in the treatment of malaria].
Topics: Animals; Antimalarials; Artemisia; Artemisinins; Chemical Phenomena; Chemistry, Physical; Humans; Malaria; Sesquiterpenes | 2005 |
The therapeutic potential of semi-synthetic artemisinin and synthetic endoperoxide antimalarial agents.
Topics: Animals; Antimalarials; Artemisinins; Humans; Malaria; Peroxides; Sesquiterpenes | 2005 |
Antimalarial drug synergism and antagonism: mechanistic and clinical significance.
Topics: Animals; Antimalarials; Artemisinins; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Folic Acid Antagonists; Humans; Malaria; Plasmodium berghei; Plasmodium falciparum; Protease Inhibitors; Quinolines; Sesquiterpenes | 2005 |
Medicinal plants and Malaria: an historical case study of research at the London School of Hygiene and Tropical Medicine in the twentieth century.
Topics: Anti-Infective Agents; Artemisia annua; Artemisinins; History, 19th Century; History, 20th Century; Humans; London; Malaria; Malaria Vaccines; Plants, Medicinal; Research; Schools, Public Health; Sesquiterpenes; Tropical Medicine | 2006 |
Medicines for Malaria Venture: sustaining antimalarial drug development.
Topics: Antimalarials; Artemisinins; Clinical Trials as Topic; Drug Design; Drug Therapy, Combination; Foundations; Humans; Malaria; Research; Sesquiterpenes; Therapies, Investigational | 2006 |
An update on malaria prevention, diagnosis and treatment for the returning traveller.
Topics: Antimalarials; Artemisinins; Humans; Malaria; Malaria Vaccines; Sesquiterpenes; Travel | 2007 |
Current malaria status and distribution of drug resistance in East and Southeast Asia with special focus to Thailand.
Topics: Age Factors; Animals; Antimalarials; Artemisinins; Asia, Southeastern; Chloroquine; Drug Resistance; Humans; Malaria; Mefloquine; Plasmodium; Quinine; Sesquiterpenes; Sex Factors; Sulfadoxine | 2007 |
The safety of artemisinins during pregnancy: a pressing question.
Topics: Anti-Infective Agents; Artemisinins; Female; Humans; Infant; Infant, Newborn; Malaria; Pregnancy; Pregnancy Complications, Parasitic; Pregnancy Outcome; Sesquiterpenes | 2007 |
Current status and progresses made in malaria chemotherapy.
Topics: Alkyl and Aryl Transferases; Animals; Antimalarials; Artemisinins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Drug Resistance; Fatty Acids; Glutathione; Glutathione Transferase; Hemeproteins; Humans; Malaria; Plasmodium falciparum; Polyamines; Sesquiterpenes; Structure-Activity Relationship; Thioredoxins | 2007 |
Rectal administration of artemisinin derivatives for the treatment of malaria.
Topics: Administration, Rectal; Area Under Curve; Artemether; Artemisinins; Artesunate; Humans; Malaria; Sesquiterpenes | 2007 |
Recent patent reviews on small molecule-based antimalarial drugs.
Topics: Aminoquinolines; Animals; Antigens, Protozoan; Antimalarials; Artemisinins; Biological Assay; Flavonoids; Hepatocyte Growth Factor; Humans; Malaria; Malaria Vaccines; Patents as Topic; Plant Extracts; Primaquine; Protease Inhibitors; Quinazolines; Triazines | 2007 |
Quantification of the antimalarial piperaquine in plasma.
Topics: Animals; Antimalarials; Artemisinins; Drug Therapy, Combination; Humans; Malaria; Quinolines; Tandem Mass Spectrometry | 2008 |
Advances in chemotherapy.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Evaluation, Preclinical; Drug Therapy, Combination; Humans; Malaria; Plasmodium; Plasmodium falciparum; Primaquine; Sesquiterpenes; Triazines | 1982 |
Qinghaosu.
Topics: Adult; Animals; Antimalarials; Artemisinins; Child; Clinical Trials as Topic; Drug Evaluation, Preclinical; Humans; Malaria; Sesquiterpenes | 1993 |
Malarial parasites and antioxidant nutrients.
Topics: Animals; Antimalarials; Antioxidants; Artemisinins; Ascorbic Acid; Dietary Fats; Drug Interactions; Malaria; Male; Mice; Nutritional Status; Oxidation-Reduction; Plasmodium; Rats; Riboflavin; Sesquiterpenes; Vitamin E Deficiency | 1993 |
The treatment of malaria.
Topics: Adult; Antimalarials; Artemisinins; Child; Chloroquine; Drug Resistance; Female; Humans; Malaria; Malaria, Falciparum; Pregnancy; Prognosis; Sesquiterpenes | 1996 |
Artemisinin and the antimalarial endoperoxides: from herbal remedy to targeted chemotherapy.
Topics: Animals; Antimalarials; Artemisinins; Clinical Trials as Topic; Drug Resistance; Humans; Malaria; Malaria, Falciparum; Peroxides; Plasmodium falciparum; Sesquiterpenes | 1996 |
The mode of action of the antimalarial artemisinin and its derivatives.
Topics: Animals; Antimalarials; Artemisinins; Humans; Malaria; Sesquiterpenes | 1996 |
Antimalarial activity of artemisinin (qinghaosu) and related trioxanes: mechanism(s) of action.
Topics: Animals; Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum; Sesquiterpenes; Structure-Activity Relationship | 1997 |
Clinical pharmacology and therapeutic potential of artemisinin and its derivatives in the treatment of malaria.
Topics: Antimalarials; Artemisinins; Humans; Malaria; Sesquiterpenes | 1996 |
Management of multiple drug-resistant malaria in Viet Nam.
Topics: Antimalarials; Artemisinins; Clinical Trials as Topic; Drug Resistance, Multiple; Humans; Malaria; Mefloquine; Sesquiterpenes; Vietnam | 1997 |
Safety assessment of peroxide antimalarials: clinical and chemical perspectives.
Topics: Animals; Antimalarials; Artemisinins; Biotransformation; Ferric Compounds; Humans; Malaria; Peroxides; Sesquiterpenes; Treatment Outcome | 1998 |
Current progress in the chemistry, medicinal chemistry and drug design of artemisinin based antimalarials.
Topics: Animals; Antimalarials; Artemisinins; Biotransformation; Drug Design; Drug Evaluation, Preclinical; Humans; Malaria; Plasmodium; Rats; Sesquiterpenes; Structure-Activity Relationship | 1999 |
Malaria: new developments in treatment and prevention.
Topics: Antimalarials; Artemisinins; Bedding and Linens; Drug Costs; Drug Resistance; Drugs, Chinese Herbal; Humans; Incidence; Malaria; Malaria Vaccines; Malaria, Falciparum; Protective Devices; Sesquiterpenes; Tropical Climate | 1999 |
Artemisinin and derivatives in the treatment of uncomplicated malaria.
Topics: Administration, Oral; Antimalarials; Artemisinins; Chemistry, Pharmaceutical; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Sesquiterpenes; Time Factors | 1998 |
The role of the qinghaosu derivatives in the treatment of severe malaria.
Topics: Adult; Antimalarials; Artemether; Artemisinins; Child; Humans; Malaria; Quinine; Research Design; Sesquiterpenes | 1998 |
Intrarectal artemisinin derivatives.
Topics: Absorption; Administration, Rectal; Adult; Antimalarials; Artemether; Artemisinins; Artesunate; Child; Humans; Malaria; Metabolic Clearance Rate; Sesquiterpenes; Suppositories | 1998 |
Qinghaosu in combinations.
Topics: Antimalarials; Artemisinins; Drug Combinations; Drug Costs; Drug Resistance; Evidence-Based Medicine; Humans; Malaria; Sesquiterpenes | 1998 |
Artemisinin drugs in the treatment of malaria: from medicinal herb to registered medication.
Topics: Animals; Antimalarials; Artemisia; Artemisinins; Clinical Trials as Topic; Drug Approval; Forecasting; Humans; Malaria; Plants, Medicinal; Sesquiterpenes; Treatment Outcome | 1999 |
Delaying antimalarial drug resistance with combination chemotherapy.
Topics: Animals; Antimalarials; Artemisinins; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Plasmodium falciparum; Plasmodium vivax; Selection, Genetic; Sesquiterpenes | 1999 |
[Why is malaria in Vietnam under control, but Africa is threatened with a malaria disaster?].
Topics: Africa; Animals; Antimalarials; Artemisinins; Communicable Disease Control; Disease Outbreaks; Drug Resistance; Humans; Malaria; Malaria, Falciparum; Mosquito Control; Sesquiterpenes; Vietnam | 2000 |
Artemisinin derivatives for treating uncomplicated malaria.
Topics: Adult; Antimalarials; Artemisinins; Humans; Malaria; Malaria, Falciparum; Sesquiterpenes | 2000 |
Artemisinin drugs: novel antimalarial agents.
Topics: Animals; Antimalarials; Artemisinins; Humans; Malaria; Plasmodium falciparum; Sesquiterpenes | 2000 |
Combination therapy for malaria in Africa: hype or hope?
Topics: Africa; Antimalarials; Artemisinins; Artesunate; Asia, Southeastern; Chloroquine; Cross-Cultural Comparison; Half-Life; Humans; Insecticide Resistance; Malaria; Mefloquine; Pyrimethamine; Self Medication; Sesquiterpenes; Sulfadoxine; Thailand | 2000 |
Why artemisinin and certain synthetic peroxides are potent antimalarials. Implications for the mode of action.
Topics: Animals; Antimalarials; Artemisinins; Humans; Malaria; Peroxides; Plasmodium; Sesquiterpenes | 2001 |
Artemisinin and derivatives: the future for malaria treatment?
Topics: Antimalarials; Artemisinins; Humans; Malaria; Sesquiterpenes | 2001 |
[Chemotherapy of parasitic diseases: current status and new advance].
Topics: Animals; Antimalarials; Antiparasitic Agents; Artemisinins; Humans; Malaria; Parasitic Diseases; Sesquiterpenes | 1998 |
Selenium and sulfur in antioxidant protective systems: relationships with vitamin E and malaria.
Topics: Antioxidants; Artemisinins; Fish Oils; Glutathione Peroxidase; Humans; Iodide Peroxidase; Lipid Peroxides; Malaria; Oxidation-Reduction; Proteins; Selenium; Selenoprotein P; Selenoproteins; Sesquiterpenes; Sulfur; Vitamin E | 1992 |
Exchange transfusion in falciparum malaria.
Topics: Animals; Antimalarials; Artemisinins; Combined Modality Therapy; Exchange Transfusion, Whole Blood; Humans; Malaria; Plasmodium falciparum; Sesquiterpenes | 1990 |
Antimalarial drugs currently in development.
Topics: Aminoquinolines; Antimalarials; Artemisinins; Atovaquone; Chemical Phenomena; Chemistry; Drug Design; Drug Evaluation, Preclinical; Drug Resistance; Humans; Malaria; Naphthoquinones; Research; Sesquiterpenes | 1989 |
Qinghaosu (artemisinin): an antimalarial drug from China.
Topics: Animals; Antimalarials; Artemisinins; Brain Diseases; Chemical Phenomena; Chemistry; Humans; Liver; Malaria; Medicine, Chinese Traditional; Metabolic Clearance Rate; Plants, Medicinal; Plasmodium berghei; Plasmodium falciparum; Sesquiterpenes | 1985 |
The problem of drug resistance in malaria.
Topics: Africa; Animals; Antimalarials; Artemisinins; Chemical Phenomena; Chemistry; Chloroquine; Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Evaluation, Preclinical; Drug Resistance, Microbial; Humans; India; Malaria; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinine; Quinolines; Sesquiterpenes; Sulfadoxine | 1985 |
New drugs and their potential use against drug-resistant malaria.
Topics: Aminoquinolines; Animals; Antimalarials; Artemisinins; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Malaria; Mefloquine; Mice; Naphthoquinones; Plasmodium falciparum; Pyrimethamine; Quinolines; Sesquiterpenes; Sulfadoxine | 1985 |
38 trial(s) available for artemisinin and Malaria
| Article | Year |
|---|---|
Artemisinin-piperaquine versus artemether-lumefantrine for treatment of uncomplicated Plasmodium falciparum malaria in Grande Comore island: an open-label, non-randomised controlled trial.
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Drug Combinations; Ethanolamines; Fluorenes; Humans; Malaria; Malaria, Falciparum; Piperazines; Plasmodium falciparum; Quinolines | 2022 |
Overall and Gender-Specific Effects of Intermittent Preventive Treatment of Malaria with Artemisinin-Based Combination Therapies among Schoolchildren in Mali: A Three-Group Open Label Randomized Controlled Trial.
Topics: Amodiaquine; Anemia; Antimalarials; Artemisinins; Artesunate; Child; Drug Combinations; Drug Therapy, Combination; Female; Hemoglobins; Humans; Malaria; Malaria, Falciparum; Mali; Pyrimethamine; Sulfadoxine | 2022 |
Therapeutic response to artemisinin combination therapies among individuals with Plasmodium falciparum single infection vs mixed Plasmodium species infections: a retrospective posthoc analysis in Kisumu County, western Kenya.
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Drug Combinations; Humans; Kenya; Malaria; Malaria, Falciparum; Plasmodium falciparum; Quinolines; Reinfection; Retrospective Studies | 2023 |
Tafenoquine co-administered with dihydroartemisinin-piperaquine for the radical cure of Plasmodium vivax malaria (INSPECTOR): a randomised, placebo-controlled, efficacy and safety study.
Topics: Antimalarials; Artemisinins; Chloroquine; Drug Therapy, Combination; Humans; Malaria; Malaria, Vivax; Plasmodium vivax; Primaquine; Quinolines | 2023 |
Efficacy and safety of pyronaridine-artesunate (PYRAMAX) for the treatment of
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Clinical Trials, Phase III as Topic; Drug Combinations; Female; Humans; Infant; Malaria; Malaria, Falciparum; Pregnancy; Pregnant Women; Randomized Controlled Trials as Topic; Sub-Saharan African People; Treatment Outcome | 2023 |
Use of malaria rapid diagnostic tests by community health workers in Afghanistan: cluster randomised trial.
Topics: Adolescent; Afghanistan; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Community Health Workers; Diagnostic Tests, Routine; Female; Humans; Infant; Infant, Newborn; Malaria; Malaria, Falciparum; Male; Plasmodium vivax; Trimethoprim, Sulfamethoxazole Drug Combination | 2017 |
Cost-effectiveness analysis of introducing malaria diagnostic testing in drug shops: A cluster-randomised trial in Uganda.
Topics: Antimalarials; Artemisinins; Commerce; Cost-Benefit Analysis; Diagnostic Tests, Routine; Drug Evaluation, Preclinical; Fever; Humans; Malaria; Private Sector; Uganda | 2017 |
Intravenous artesunate plus Artemisnin based Combination Therapy (ACT) or intravenous quinine plus ACT for treatment of severe malaria in Ugandan children: a randomized controlled clinical trial.
Topics: Administration, Intravenous; Antimalarials; Artemisinins; Artesunate; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Kaplan-Meier Estimate; Malaria; Male; Quinine; Risk Factors; Treatment Outcome; Uganda | 2017 |
Improving rational use of ACTs through diagnosis-dependent subsidies: Evidence from a cluster-randomized controlled trial in western Kenya.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Child, Preschool; Community Health Workers; Drug Combinations; Drug Costs; Female; Healthcare Financing; Humans; Infant; Kenya; Malaria; Male; Medication Adherence; Nonprescription Drugs; Point-of-Care Testing; Predictive Value of Tests; Private Sector; Public-Private Sector Partnerships; Time Factors; Treatment Outcome | 2018 |
Artemisinin-based combination therapy during pregnancy: outcome of pregnancy and infant mortality: a cohort study.
Topics: Adolescent; Adult; Africa South of the Sahara; Antimalarials; Artemisinins; Cohort Studies; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Infant; Infant Mortality; Infant, Newborn; Malaria; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Young Adult | 2019 |
The effect of an anti-malarial subsidy programme on the quality of service provision of artemisinin-based combination therapy in Kenya: a cluster-randomized, controlled trial.
Topics: Antimalarials; Artemisinins; Child, Preschool; Cross-Sectional Studies; Drug Therapy, Combination; Female; Health Services Research; Humans; Infant; Kenya; Malaria; Male; Pharmacies; Quality of Health Care | 2013 |
High adherence to antimalarials and antibiotics under integrated community case management of illness in children less than five years in eastern Uganda.
Topics: Anti-Bacterial Agents; Antimalarials; Artemisinins; Case Management; Child, Preschool; Cohort Studies; Female; Humans; Infant; Malaria; Male; Medication Adherence; Uganda | 2013 |
Artemisinin-based combination therapies are efficacious and safe for treatment of uncomplicated malaria in HIV-infected Ugandan children.
Topics: Antimalarials; Artemisinins; Child, Preschool; Cohort Studies; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infant; Lopinavir; Malaria; Male; Nevirapine; Parasitemia; Quinolines; Reverse Transcriptase Inhibitors; Ritonavir; Treatment Outcome; Uganda | 2014 |
Economic evaluation of a cluster randomized trial of interventions to improve health workers' practice in diagnosing and treating uncomplicated malaria in Cameroon.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Cameroon; Child; Child, Preschool; Cost-Benefit Analysis; Diagnostic Tests, Routine; Drug Therapy, Combination; Female; Fever; Health Facilities; Health Personnel; Humans; Infant; Inservice Training; Malaria; Malaria, Falciparum; Male; Middle Aged; Young Adult | 2014 |
Validation and pharmacokinetic application of a high-performance liquid chromatographic technique for determining the concentrations of amodiaquine and its metabolite in plasma of patients treated with oral fixed-dose amodiaquine-artesunate combination in
Topics: Administration, Oral; Adult; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Chromatography, High Pressure Liquid; Drug Combinations; Female; Humans; Malaria; Malaria, Falciparum; Male; Nigeria; Young Adult | 2015 |
Seasonal malaria chemoprevention in an area of extended seasonal transmission in Ashanti, Ghana: an individually randomised clinical trial.
Topics: Amodiaquine; Antimalarials; Artemether; Artemisinins; Chemoprevention; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Ghana; Humans; Infant; Infant, Newborn; Lumefantrine; Malaria; Male; Pyrimethamine; Quinolines; Rain; Seasons; Sulfadoxine | 2016 |
Appropriate targeting of artemisinin-based combination therapy by community health workers using malaria rapid diagnostic tests: findings from randomized trials in two contrasting areas of high and low malaria transmission in south-western Uganda.
Topics: Adult; Antimalarials; Artemisinins; Child, Preschool; Clinical Decision-Making; Community Health Workers; Female; Fever; Humans; Infant; Malaria; Male; Parasitemia; Practice Guidelines as Topic; Uganda | 2016 |
Malaria Rapid Diagnostic Tests and Malaria Microscopy for Guiding Malaria Treatment of Uncomplicated Fevers in Nigeria and Prereferral Cases in 3 African Countries.
Topics: Artemisinins; Burkina Faso; Child; Child, Preschool; Community Health Workers; Diagnostic Tests, Routine; Drug Therapy, Combination; Female; Fever; Humans; Infant; Malaria; Male; Microscopy; Nigeria; Parasitemia; Uganda | 2016 |
Quantifying and Valuing Community Health Worker Time in Improving Access to Malaria Diagnosis and Treatment.
Topics: Adult; Antimalarials; Artemisinins; Artesunate; Burkina Faso; Community Health Workers; Diagnostic Tests, Routine; Female; Humans; Malaria; Male; Middle Aged; Nigeria; Rural Population; Surveys and Questionnaires; Time Factors; Uganda; Young Adult | 2016 |
Effect of nutritional status on response to treatment with artemisinin-based combination therapy in young Ugandan children with malaria.
Topics: Antimalarials; Artemisinins; Drug Therapy, Combination; Humans; Infant; Malaria; Malnutrition; Parasitemia; Quinolines | 2011 |
Malaria rapid testing by community health workers is effective and safe for targeting malaria treatment: randomised cross-over trial in Tanzania.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Child; Child, Preschool; Community Health Services; Community Health Workers; Cross-Over Studies; Diagnostic Tests, Routine; Drug Therapy, Combination; Female; Fever; Health Personnel; Humans; Malaria; Male; Middle Aged; Outcome Assessment, Health Care; Tanzania | 2011 |
The efficacy and tolerability of artemisinin-piperaquine (Artequick®) versus artesunate-amodiaquine (Coarsucam™) for the treatment of uncomplicated Plasmodium falciparum malaria in south-central Vietnam.
Topics: Adolescent; Adult; Amodiaquine; Animals; Artemisinins; Blood; Child; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Malaria; Male; Middle Aged; Plasmodium falciparum; Polymerase Chain Reaction; Quinolines; Time Factors; Treatment Outcome; Vietnam; Young Adult | 2012 |
Integrated community case management of fever in children under five using rapid diagnostic tests and respiratory rate counting: a multi-country cluster randomized trial.
Topics: Anti-Bacterial Agents; Antimalarials; Artemisinins; Burkina Faso; Case Management; Child, Preschool; Cluster Analysis; Community Health Services; Diagnostic Tests, Routine; Disease Management; Female; Fever; Ghana; Humans; Inappropriate Prescribing; Infant; Malaria; Male; Pneumonia; Respiratory Rate; Treatment Outcome; Uganda | 2012 |
Increasing incidence of malaria in children despite insecticide-treated bed nets and prompt anti-malarial therapy in Tororo, Uganda.
Topics: Age Factors; Antimalarials; Artemisinins; Child, Preschool; Cohort Studies; Female; Humans; Incidence; Infant; Insecticide-Treated Bednets; Malaria; Male; Mosquito Control; Parasitemia; Risk Factors; Seasons; Uganda | 2012 |
Artemisinin versus nonartemisinin combination therapy for uncomplicated malaria: randomized clinical trials from four sites in Uganda.
Topics: Amodiaquine; Antimalarials; Artemisinins; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Genotype; Humans; Infant; Infections; Malaria; Male; Pyrimethamine; Risk Factors; Sesquiterpenes; Sulfadoxine; Treatment Outcome; Uganda | 2005 |
Differences in willingness to pay for artemisinin-based combinations or monotherapy: experiences from the United Republic of Tanzania.
Topics: Anti-Infective Agents; Antimalarials; Artemisinins; Child, Preschool; Drug Therapy, Combination; Female; Financing, Personal; Humans; Infant; Malaria; Male; Sesquiterpenes; Tanzania | 2005 |
Minor liver profile dysfunctions in Plasmodium vivax, P. malaria and P. ovale patients and normalization after treatment.
Topics: Adolescent; Adult; Alanine Transaminase; Animals; Anti-Infective Agents; Artemisinins; Bilirubin; Female; Humans; Liver; Liver Function Tests; Malaria; Malaria, Vivax; Male; Middle Aged; Plasmodium malariae; Plasmodium ovale; Plasmodium vivax; Serum Albumin; Sesquiterpenes; Treatment Outcome | 2006 |
The safety of artemisinins during pregnancy: a pressing question.
Topics: Anti-Infective Agents; Artemisinins; Female; Humans; Infant; Infant, Newborn; Malaria; Pregnancy; Pregnancy Complications, Parasitic; Pregnancy Outcome; Sesquiterpenes | 2007 |
Feasibility and acceptability of artemisinin-based combination therapy for the home management of malaria in four African sites.
Topics: Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child, Preschool; Drug Combinations; Ethanolamines; Feasibility Studies; Fever; Fluorenes; Ghana; Humans; Infant; Malaria; Nigeria; Patient Acceptance of Health Care; Treatment Outcome; Uganda | 2008 |
Antimalarial activity of mefloquine and qinghaosu.
Topics: Administration, Oral; Adolescent; Adult; Antimalarials; Artemisinins; Child; China; Female; Humans; Injections, Intramuscular; Malaria; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Quinolines; Sesquiterpenes; Time Factors | 1982 |
Randomised comparative study of mefloquine, qinghaosu, and pyrimethamine-sulfadoxine in patients with falciparum malaria.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; China; Clinical Trials as Topic; Drug Combinations; Drug Therapy, Combination; Female; Humans; Malaria; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Prospective Studies; Pyrimethamine; Quinolines; Random Allocation; Sesquiterpenes; Sulfadoxine; Sulfanilamides | 1984 |
Antimalarial efficacy and mode of action of qinghaosu and its derivatives in experimental models. China Cooperative Research Group on qinghaosu and its derivatives as antimalarials.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Erythrocytes; Malaria; Mice; Multicenter Studies as Topic; Plasmodium; Sesquiterpenes | 1982 |
Clinical studies on the treatment of malaria with qinghaosu and its derivatives. China Cooperative Research Group on qinghaosu and its derivatives as antimalarials.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Humans; Malaria; Multicenter Studies as Topic; Plasmodium falciparum; Plasmodium vivax; Sesquiterpenes | 1982 |
Artemisinin kinetics and dynamics during oral and rectal treatment of uncomplicated malaria.
Topics: Administration, Oral; Administration, Rectal; Adult; Antimalarials; Area Under Curve; Artemisinins; Humans; Malaria; Male; Middle Aged; Sesquiterpenes; Time Factors; Vietnam | 1998 |
Effect of artemisinin on lipid peroxidation and fluidity of the erythrocyte membrane in malaria.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Cyclic N-Oxides; Deferoxamine; Double-Blind Method; Erythrocyte Membrane; Humans; Lipid Peroxidation; Malaria; Malaria, Falciparum; Membrane Fluidity; Plasmodium falciparum; Sesquiterpenes; Thiobarbituric Acid Reactive Substances | 2000 |
Artemisinin pharmacokinetics and efficacy in uncomplicated-malaria patients treated with two different dosage regimens.
Topics: Adult; Aging; Antimalarials; Area Under Curve; Artemisinins; Chromatography, High Pressure Liquid; Double-Blind Method; Female; Humans; Malaria; Male; Recurrence; Saliva; Sesquiterpenes; Sex Characteristics; Spectrophotometry, Ultraviolet; Vietnam | 2002 |
[Comparative study of artemisinin suppositories and piperaquine phosphate in the treatment of falciparum malaria].
Topics: Adolescent; Adult; Aged; Animals; Antimalarials; Artemisinins; Child; Female; Humans; Malaria; Male; Middle Aged; Plasmodium falciparum; Quinolines; Sesquiterpenes; Suppositories | 1989 |
The problem of drug resistance in malaria.
Topics: Africa; Animals; Antimalarials; Artemisinins; Chemical Phenomena; Chemistry; Chloroquine; Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Evaluation, Preclinical; Drug Resistance, Microbial; Humans; India; Malaria; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinine; Quinolines; Sesquiterpenes; Sulfadoxine | 1985 |
454 other study(ies) available for artemisinin and Malaria
| Article | Year |
|---|---|
Antiplasmodial phloroglucinol derivatives from Syncarpia glomulifera.
Topics: Antimalarials; Cell Survival; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Malaria; Molecular Structure; Myrtaceae; Parasitic Sensitivity Tests; Phloroglucinol; Plant Bark; Plasmodium falciparum; Structure-Activity Relationship | 2016 |
Discovery of a Quinoline-4-carboxamide Derivative with a Novel Mechanism of Action, Multistage Antimalarial Activity, and Potent in Vivo Efficacy.
Topics: Animals; Antimalarials; Disease Models, Animal; Drug Discovery; Malaria; Mice; Molecular Structure; Plasmodium falciparum; Quinolines; Structure-Activity Relationship | 2016 |
Docking, synthesis and antimalarial activity of novel 4-anilinoquinoline derivatives.
Topics: Aniline Compounds; Antimalarials; Cysteine Endopeptidases; Hemeproteins; Humans; Malaria; Molecular Docking Simulation; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Protozoan Proteins; Quinolines; Structure-Activity Relationship | 2017 |
Antimalarial Activities of Alkyl Cyclohexenone Derivatives Isolated from the Leaves of Poupartia borbonica.
Topics: Anacardiaceae; Animals; Antimalarials; Belgium; Cyclohexanones; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Flavonoids; HeLa Cells; Humans; Inhibitory Concentration 50; Malaria; Mice; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Parasitic Sensitivity Tests; Plant Leaves; Plasmodium berghei; Plasmodium falciparum; Quercetin; Zebrafish | 2017 |
Benzoxaborole Antimalarial Agents. Part 5. Lead Optimization of Novel Amide Pyrazinyloxy Benzoxaboroles and Identification of a Preclinical Candidate.
Topics: Amides; Animals; Antimalarials; Boron Compounds; Dogs; Female; Humans; Malaria; Malaria, Falciparum; Male; Mice; Plasmodium berghei; Plasmodium falciparum; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship | 2017 |
Development of Novel Peptide-Based Michael Acceptors Targeting Rhodesain and Falcipain-2 for the Treatment of Neglected Tropical Diseases (NTDs).
Topics: Antimalarials; Carbamates; Cathepsin L; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dipeptides; HeLa Cells; Humans; Hydrogen Bonding; Malaria; Molecular Docking Simulation; Molecular Dynamics Simulation; Neglected Diseases; Phenylalanine; Plasmodium falciparum; Stereoisomerism; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2017 |
Discovery of new antimalarial agents: Second-generation dual inhibitors against FP-2 and PfDHFR via fragments assembely.
Topics: Animals; Antimalarials; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Drug Discovery; Folic Acid Antagonists; Malaria; Mice; Mice, Inbred BALB C; Molecular Docking Simulation; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase | 2017 |
4-Aryl Pyrrolidines as a Novel Class of Orally Efficacious Antimalarial Agents. Part 1: Evaluation of 4-Aryl- N-benzylpyrrolidine-3-carboxamides.
Topics: Administration, Oral; Animals; Antimalarials; Biological Availability; Disease Models, Animal; Drug Evaluation, Preclinical; Malaria; Mice; Microsomes, Liver; Pyrrolidines; Structure-Activity Relationship | 2019 |
Synthesis and structure-activity relationships for new 6-fluoroquinoline derivatives with antiplasmodial activity.
Topics: Animals; Antimalarials; Cell Line; Cell Survival; Disease Models, Animal; Drug Resistance; Malaria; Mice; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Quinolines; Structure-Activity Relationship | 2019 |
In vitro and in vivo antiplasmodial activity of novel quinoline derivative compounds by molecular hybridization.
Topics: Animals; Antimalarials; Cell Line; Erythrocytes; Female; Hemeproteins; Hemin; Hemolysis; Humans; Malaria; Mice; Plasmodium falciparum; Quinolines | 2021 |
Combating multi-drug resistant malaria parasite by inhibiting falcipain-2 and heme-polymerization: Artemisinin-peptidyl vinyl phosphonate hybrid molecules as new antimalarials.
Topics: Antimalarials; Artemisinins; Cysteine Endopeptidases; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Heme; Malaria; Molecular Structure; Organophosphonates; Parasitic Sensitivity Tests; Peptides; Plasmodium falciparum; Polymerization; Structure-Activity Relationship; Vinyl Compounds | 2021 |
Synthesis of novel 1,2,4-trioxanes and antimalarial evaluation against multidrug-resistant Plasmodium yoelii nigeriensis.
Topics: Administration, Oral; Animals; Antimalarials; Drug Resistance, Microbial; Drug Resistance, Multiple; Heterocyclic Compounds; Injections, Intramuscular; Malaria; Mice; Parasitic Sensitivity Tests; Plasmodium yoelii | 2021 |
Novel naphthyl based 1,2,4-trioxanes: Synthesis and in vivo efficacy in the Plasmodium yoelii nigeriensis in Swiss mice.
Topics: Animals; Antimalarials; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Heterocyclic Compounds; Malaria; Mice; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium yoelii; Structure-Activity Relationship | 2021 |
Novel hydrazone derivatives of N-amino-11-azaartemisinin with high order of antimalarial activity against multidrug-resistant Plasmodium yoelii nigeriensis in Swiss mice via intramuscular route.
Topics: Animals; Antimalarials; Artemisinins; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Hydrazones; Malaria; Mice; Molecular Structure; Plasmodium yoelii; Structure-Activity Relationship | 2022 |
To what extent are the antimalarial markets in African countries ready for a transition to triple artemisinin-based combination therapies?
Topics: Antimalarials; Artemisinins; Burkina Faso; Drug Approval; Drug Therapy, Combination; Focus Groups; Humans; Malaria; Marketing; Nigeria; Patient Acceptance of Health Care; Practice Guidelines as Topic; Prescription Drugs; Private Sector; Public Sector; Social Control, Formal | 2021 |
Can repurposing drugs play a role in malaria control?
Topics: Antimalarials; Artemisinins; Drug Repositioning; Drug Resistance, Microbial; Female; Humans; Imatinib Mesylate; Malaria; Malaria, Falciparum; Plasmodium falciparum; Pregnancy; Pregnancy Complications, Parasitic | 2021 |
The parasitophorous vacuole nutrient channel is critical for drug access in malaria parasites and modulates the artemisinin resistance fitness cost.
Topics: Amino Acids; Animals; Antimalarials; Artemisinins; Drug Design; Exercise; Humans; Malaria; Nutrients; Parasites; Up-Regulation; Vacuoles | 2021 |
Risk factors associated with malaria infection identified through reactive case detection in Zanzibar, 2012-2019.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Child; Child, Preschool; Cross-Sectional Studies; Diagnostic Tests, Routine; Drug Combinations; Female; Humans; Infant; Infant, Newborn; Malaria; Male; Middle Aged; Risk Factors; Tanzania; Young Adult | 2021 |
Malaria treatment-seeking behaviour and its associated factors: A cross-sectional study in rural East Nusa Tenggara Province, Indonesia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Artemisinins; Cross-Sectional Studies; Female; Guideline Adherence; Humans; Indonesia; Malaria; Male; Middle Aged; Multivariate Analysis; Patient Acceptance of Health Care; Patient Participation; Rural Health Services; Rural Population; Time-to-Treatment; Treatment Outcome; Young Adult | 2022 |
Ferroptosis plays an essential role in the antimalarial mechanism of low-dose dihydroartemisinin.
Topics: Animals; Antimalarials; Artemisinins; Cell Death; Female; Ferroptosis; Humans; Malaria; Mice; Mice, Inbred C57BL; Parasites; Piperazines; Reactive Oxygen Species; Sorafenib | 2022 |
An update on pharmacogenetic factors influencing the metabolism and toxicity of artemisinin-based combination therapy in the treatment of malaria.
Topics: Antimalarials; Artemisinins; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Malaria, Falciparum; Pharmacogenetics; Plasmodium falciparum | 2022 |
Evidence of Artemisinin-Resistant Malaria in Africa.
Topics: Africa; Antimalarials; Artemisinins; Humans; Malaria | 2022 |
Evidence of Artemisinin-Resistant Malaria in Africa. Reply.
Topics: Africa; Antimalarials; Artemisinins; Humans; Malaria | 2022 |
Dimeric Artesunate Glycerophosphocholine Conjugate Nano-Assemblies as Slow-Release Antimalarials to Overcome Kelch 13 Mutant Artemisinin Resistance.
Topics: Antimalarials; Artemisinins; Artesunate; Cryoelectron Microscopy; Drug Resistance; Humans; Liposomes; Malaria; Malaria, Falciparum; Plasmodium falciparum | 2022 |
Is triple artemisinin-based combination therapy necessary for uncomplicated malaria?
Topics: Antimalarials; Artemisinins; Drug Combinations; Drug Therapy, Combination; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum | 2022 |
Is triple artemisinin-based combination therapy necessary for uncomplicated malaria?
Topics: Antimalarials; Artemisinins; Drug Combinations; Drug Therapy, Combination; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum | 2022 |
Misstatements in Artemisinin-Based Combination Therapies in Malaria Treatment.
Topics: Antimalarials; Artemisinins; Drug Resistance; Drug Therapy, Combination; Humans; Malaria | 2022 |
"Misstatements in Artemisinin-Based Combination Therapies in Malaria Treatment" by Fleckenstein and Miller.
Topics: Antimalarials; Artemisinins; Drug Resistance; Drug Therapy, Combination; Humans; Malaria | 2022 |
Plasmodium falciparum sexual conversion rates can be affected by artemisinin-based treatment in naturally infected malaria patients.
Topics: Animals; Antimalarials; Artemisinins; Canada; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum | 2022 |
Malaria frontline project: pre-intervention Malaria baseline assessment in Kano and Zamfara States, August 2016.
Topics: Artemisinins; Cross-Sectional Studies; Female; Humans; Insecticide-Treated Bednets; Insecticides; Malaria; Mosquito Control; Nigeria; Pregnancy; Quinine; United States | 2021 |
Impact of Drug Exposure on Resistance Selection Following Artemether-Lumefantrine Treatment for Malaria in Children With and Without HIV in Uganda.
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Drug Combinations; Fluorenes; HIV Infections; Humans; Lopinavir; Lumefantrine; Malaria; Malaria, Falciparum; Nevirapine; Ritonavir; Uganda | 2023 |
Targeting Artemisinin-Resistant Malaria by Repurposing the Anti-Hepatitis C Virus Drug Alisporivir.
Topics: Antimalarials; Artemisinins; Cyclosporine; Drug Repositioning; Drug Resistance; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum | 2022 |
Malaria outbreak in Laos caused by formerly rare artemisinin resistant strains of Plasmodium falciparum.
Topics: Antimalarials; Artemisinins; Drug Resistance; Humans; Laos; Malaria; Malaria, Falciparum; Plasmodium falciparum | 2023 |
A Plasmodium falciparum ubiquitin-specific protease (PfUSP) is essential for parasite survival and its disruption enhances artemisinin efficacy.
Topics: Animals; Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria; Parasites; Plasmodium falciparum; Proteasome Endopeptidase Complex; Ubiquitin; Ubiquitin-Specific Proteases | 2023 |
Dinuclear and mononuclear metal(II) polypyridyl complexes against drug-sensitive and drug-resistant Plasmodium falciparum and their mode of action.
Topics: Antimalarials; Artemisinins; Coordination Complexes; Copper; Drug Resistance; Humans; Malaria; Malaria, Falciparum; Metals; Plasmodium falciparum; Zinc | 2022 |
Assessment of artemisinin tolerance in Plasmodium falciparum clinical isolates in children with uncomplicated malaria in Ghana.
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Drug Combinations; Drug Tolerance; Ghana; Humans; Lumefantrine; Malaria; Malaria, Falciparum; Plasmodium falciparum | 2023 |
Anti-malarial drug use, appropriateness and associated factors among children under-five with febrile illnesses presenting to a tertiary health facility: a cross sectional study.
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Child, Preschool; Cross-Sectional Studies; Fever; Humans; Malaria | 2023 |
[POST-ARTEMISININ DELAYED HEMOLYSIS AFTER TREATMENT OF MALARIA].
Topics: Anemia; Antimalarials; Artemisinins; Hemolysis; Humans; Malaria; Malaria, Falciparum | 2023 |
Nutrient Limitation Mimics Artemisinin Tolerance in Malaria.
Topics: Antimalarials; Artemisinins; Drug Resistance; Drug Tolerance; Humans; Malaria; Nutrients; Plasmodium falciparum | 2023 |
Monitoring antimalarial drug-resistance markers in Somalia.
Topics: Antimalarials; Chloroquine; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum; Somalia | 2023 |
Clinical characteristics of platelet-mediated killing circulating parasite of major human malaria.
Topics: Animals; Artemisinins; Blood Platelets; Humans; Malaria; Parasites; Retrospective Studies; Thrombocytopenia | 2023 |
Activity of Ivermectin and Its Metabolites against Asexual Blood Stage Plasmodium falciparum and Its Interactions with Antimalarial Drugs.
Topics: Animals; Antimalarials; Artemisinins; Drug Combinations; Drug Resistance; Humans; Ivermectin; Malaria; Malaria, Falciparum; Plasmodium falciparum | 2023 |
Curcumin or quercetin loaded nutriosomes as oral adjuvants for malaria infections.
Topics: Adenocarcinoma; Adjuvants, Immunologic; Adjuvants, Pharmaceutic; Antimalarials; Artemisinins; Caco-2 Cells; Colonic Neoplasms; Curcumin; Endothelial Cells; Humans; Liposomes; Malaria; Quercetin | 2023 |
Nonclassical mechanisms to irreversibly suppress β-hematin crystal growth.
Topics: Antimalarials; Crystallization; Hemin; Humans; Malaria; Quinolines | 2023 |
Application of loop-mediated isothermal amplification combined with lateral flow assay visualization of Plasmodium falciparum kelch 13 C580Y mutation for artemisinin resistance detection in clinical samples.
Topics: Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria; Malaria, Falciparum; Mutation; Plasmodium falciparum | 2023 |
Tackling the emerging Artemisinin-resistant malaria parasite by modulation of defensive oxido-reductive mechanism via nitrofurantoin repurposing.
Topics: Animals; Antimalarials; Artemisinins; Drug Repositioning; Malaria; Mice; Nitrofurantoin; Parasites | 2023 |
Evolution of Partial Resistance to Artemisinins in Malaria Parasites in Uganda.
Topics: Animals; Artemisinins; Benchmarking; Drug Resistance; Humans; Malaria; Parasites; Protozoan Proteins; Uganda | 2023 |
Healthcare provider and drug dispenser knowledge and adherence to guidelines for the case management of malaria in pregnancy in the context of multiple first-line artemisinin-based combination therapy in western Kenya.
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Case Management; Cross-Sectional Studies; Female; Humans; Kenya; Malaria; Pregnancy; Quinine | 2023 |
The temporal dynamics of Plasmodium species infection after artemisinin-based combination therapy (ACT) among asymptomatic children in the Hohoe municipality, Ghana.
Topics: Artemisinins; Child; Ghana; Humans; Malaria; Malaria, Falciparum; Nucleic Acids; Plasmodium malariae | 2023 |
Artemisinin-Resistant and HRP-Negative Malaria Parasites in Africa.
Topics: Africa; Animals; Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria; Malaria, Falciparum; Plasmodium; Plasmodium falciparum | 2023 |
Modeling to guide drug policy response to artemisinin-resistant malaria in Rwanda.
Topics: Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum; Policy; Rwanda | 2023 |
The volatilome signatures of Plasmodium falciparum parasites during the intraerythrocytic development cycle in vitro under exposure to artemisinin drug.
Topics: Animals; Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria; Malaria, Falciparum; Parasites; Plasmodium falciparum; Protozoan Proteins; Volatile Organic Compounds | 2023 |
Forest Fevers: traditional treatment of malaria in the southern lowlands of Laos.
Topics: Aged; Aged, 80 and over; Artemisinins; Fever; Forests; Humans; Laos; Malaria; Male; Medicine, African Traditional; Middle Aged; Phytotherapy; Plant Preparations; Plants, Medicinal | 2020 |
Health workers' perception of malaria rapid diagnostic test and factors influencing compliance with test results in Ebonyi state, Nigeria.
Topics: Adult; Antimalarials; Artemisinins; Cross-Sectional Studies; Diagnostic Tests, Routine; Drug Prescriptions; Drug Therapy, Combination; Female; Health Personnel; Hospitals; Humans; Malaria; Male; Nigeria; Perception; Reagent Kits, Diagnostic; Surveys and Questionnaires; Tertiary Care Centers | 2019 |
Prevalence of asymptomatic malaria parasitaemia following mass testing and treatment in Pakro sub-district of Ghana.
Topics: Adolescent; Anti-Infective Agents; Artemisinins; Child; Child, Preschool; Combined Modality Therapy; Feasibility Studies; Female; Ghana; Humans; Infant; Malaria; Male; Mass Screening; Parasitemia; Prevalence; Retrospective Studies; Treatment Outcome | 2019 |
Efavirenz-Based Antiretroviral Therapy Reduces Artemether-Lumefantrine Exposure for Malaria Treatment in HIV-Infected Pregnant Women.
Topics: Adolescent; Adult; Alkynes; Anti-HIV Agents; Anti-Retroviral Agents; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Benzoxazines; Cyclopropanes; Drug Combinations; Drug Interactions; Female; HIV Infections; Humans; Lumefantrine; Malaria; Malaria, Falciparum; Pregnancy; Prospective Studies; Uganda; Young Adult | 2020 |
Health gains and financial risk protection afforded by public financing of selected malaria interventions in Ethiopia: an extended cost-effectiveness analysis.
Topics: Anti-Infective Agents; Artemisinins; Cost-Benefit Analysis; Ethiopia; Health Expenditures; Humans; Incidence; Income; Insecticide-Treated Bednets; Insecticides; Malaria; Malaria Vaccines; Risk Factors; Socioeconomic Factors | 2020 |
Healthcare professionals' perspective can guide post-marketing surveillance of artemisinin-based combination therapy in Uganda.
Topics: Adult; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Cross-Sectional Studies; Drug Resistance; Drug Therapy, Combination; Female; Health Personnel; Humans; Logistic Models; Malaria; Male; Patient Compliance; Plasmodium falciparum; Product Surveillance, Postmarketing; Quinolines; Sesquiterpenes; Surveys and Questionnaires; Tablets; Treatment Failure; Uganda | 2020 |
Dried Leaf
Topics: Animals; Artemisia annua; Artemisinins; Biological Availability; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Female; Humans; Liver; Malaria; Male; Microsomes, Liver; Plant Extracts; Plant Leaves; Rats; Rats, Sprague-Dawley | 2020 |
The fidelity of implementation of recommended care for children with malaria by community health workers in Nigeria.
Topics: Adult; Antimalarials; Artemisinins; Caregivers; Child, Preschool; Clinical Protocols; Community Health Workers; Counseling; Drug Therapy, Combination; Employee Performance Appraisal; Female; Humans; Implementation Science; Infant; Inservice Training; Malaria; Microbiological Techniques; Middle Aged; Nigeria; Socioeconomic Factors | 2020 |
Cholesterol-dependent enrichment of understudied erythrocytic stages of human Plasmodium parasites.
Topics: Artemisinins; Cell Separation; Cholesterol; Erythrocytes; Humans; Malaria; Metabolomics; Parasitology; Plasmodium | 2020 |
Bridging the quality gap in diagnosis and treatment of malaria.
Topics: Africa South of the Sahara; Anti-Infective Agents; Antimalarials; Artemisinins; Child, Preschool; Disease Eradication; Female; Health Services Accessibility; Humans; Infant; Malaria; Male; Mosquito Control; Pregnancy; Pregnancy Complications, Parasitic; Professional Practice Gaps; Quality of Health Care | 2020 |
Optimal Approach and Strategies to Strengthen Pharmacovigilance in Sub-Saharan Africa: A Cohort Study of Patients Treated with First-Line Artemisinin-Based Combination Therapies in the Nanoro Health and Demographic Surveillance System, Burkina Faso.
Topics: Adolescent; Amodiaquine; Antimalarials; Artemisinins; Burkina Faso; Child; Child, Preschool; Cohort Studies; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Infant; Infant, Newborn; Lumefantrine; Malaria; Male; Pharmacovigilance; Pregnancy; Prospective Studies; Structure-Activity Relationship | 2020 |
Impact of substandard and falsified antimalarials in Zambia: application of the SAFARI model.
Topics: Antimalarials; Artemisinins; Child; Child, Preschool; Computer Simulation; Counterfeit Drugs; Humans; Income; Infant; Malaria; Models, Economic; Models, Theoretical; Patient Acceptance of Health Care; Zambia | 2020 |
A protocol for systematic review and meta-analysis of optimizing treatment for malaria.
Topics: Anti-Infective Agents; Antimalarials; Artemisinins; Combined Modality Therapy; Female; Humans; Malaria; Male; Meta-Analysis as Topic; Plasmodium falciparum; Randomized Controlled Trials as Topic; Research Design; Safety; Systematic Reviews as Topic; Treatment Failure; Treatment Outcome | 2020 |
Clinical Probe of Cyp2C8*2 Mutants in a Malaria Hyperendemic Zone: Evidence from North-Central, Nigeria.
Topics: Adult; Amodiaquine; Antimalarials; Artemisinins; Chloroquine; Cytochrome P-450 CYP2C8; Drug Resistance; Female; Humans; Malaria; Male; Nigeria; Pharmacogenomic Testing; Plasmodium falciparum | 2020 |
Lack of Consistent Malaria Incidence Hotspots in a Highland Kenyan Area During a 10-Year Period of Very Low and Unstable Transmission.
Topics: Anti-Infective Agents; Artemisinins; Disease Hotspot; Humans; Incidence; Kenya; Longitudinal Studies; Malaria | 2020 |
Artemisinin-Ginkgo biloba extract combination therapy for Plasmodium yoelii.
Topics: Animals; Antimalarials; Artemisinins; Blood Circulation; Drug Therapy, Combination; Gene Expression; Ginkgo biloba; Immunity, Innate; Malaria; Male; Mice; Mice, Inbred BALB C; Plant Extracts; Plasmodium yoelii | 2021 |
Mammalian Deubiquitinating Enzyme Inhibitors Display
Topics: Animals; Artemisinins; Deubiquitinating Enzymes; Drug Resistance; Humans; Malaria; Plasmodium falciparum | 2021 |
Histone acetyltransferase PfGCN5 regulates stress responsive and artemisinin resistance related genes in Plasmodium falciparum.
Topics: Antimalarials; Artemisinins; Drug Resistance; Histone Acetyltransferases; Humans; Malaria; Malaria, Falciparum; p300-CBP Transcription Factors; Plasmodium falciparum; Protozoan Proteins; Stress, Physiological | 2021 |
Seeking research questions from implementers: considerations for leveraging ground actors research needs in the fight against malaria in West Africa.
Topics: Africa, Western; Antimalarials; Artemisinins; Chemoprevention; Child, Preschool; Communicable Disease Control; Community Participation; Drug Combinations; Humans; Infant; Infant, Newborn; Malaria | 2021 |
Artemisinin combination therapy fails even in the absence of Plasmodium falciparum kelch13 gene polymorphism in Central India.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Drug Resistance; Drug Therapy, Combination; Female; Humans; India; Kelch Repeat; Malaria; Malaria, Falciparum; Male; Middle Aged; Mutation; Phenotype; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Pyrimethamine; Sulfadoxine; Tetrahydrofolate Dehydrogenase; Treatment Outcome | 2021 |
Functional analyses of plasmodium ferredoxin Asp97Tyr mutant related to artemisinin resistance of human malaria parasites.
Topics: Animals; Antimalarials; Artemisinins; Aspartic Acid; Electron Transport; Ferredoxin-NADP Reductase; Ferredoxins; Humans; Kinetics; Malaria; Mutation; Parasites; Plasmodium falciparum; Protozoan Proteins; Tyrosine | 2021 |
Therapeutic efficacy and artemisinin resistance in northern Myanmar: evidence from in vivo and molecular marker studies.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Child; Child, Preschool; DNA, Protozoan; Drug Resistance; Drug Therapy, Combination; Female; Genes, Protozoan; Humans; Malaria; Male; Middle Aged; Myanmar; Plasmodium; Polymorphism, Genetic; Prospective Studies; Sequence Analysis, DNA; Treatment Outcome; Young Adult | 2017 |
Insights into the availability and distribution of oral artemisinin monotherapy in Myanmar: evidence from a nationally representative outlet survey.
Topics: Antimalarials; Artemisinins; Community Health Workers; Humans; Malaria; Myanmar; Private Sector | 2017 |
Malaria profiles and challenges in artemisinin resistance containment in Myanmar.
Topics: Antimalarials; Artemisinins; Cross-Sectional Studies; Drug Resistance; Humans; Incidence; Malaria; Myanmar; Plasmodium | 2017 |
Evidence on anti-malarial and diagnostic markets in Cambodia to guide malaria elimination strategies and policies.
Topics: Antimalarials; Artemisinins; Cambodia; Cross-Sectional Studies; Diagnostic Tests, Routine; Drug Combinations; Humans; Malaria; Private Sector; Public Sector | 2017 |
Molecular Profile of Malaria Drug Resistance Markers of Plasmodium falciparum in Suriname.
Topics: Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Genotype; Malaria; Mutation; Plasmodium falciparum; Protozoan Proteins; Suriname | 2017 |
What happened to anti-malarial markets after the Affordable Medicines Facility-malaria pilot? Trends in ACT availability, price and market share from five African countries under continuation of the private sector co-payment mechanism.
Topics: Africa South of the Sahara; Antimalarials; Artemisinins; Commerce; Drug Combinations; Health Facilities; Madagascar; Malaria; Pilot Projects; Private Sector | 2017 |
Haemoglobin changes and risk of anaemia following treatment for uncomplicated falciparum malaria in sub-Saharan Africa.
Topics: Adolescent; Africa South of the Sahara; Anemia; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Therapy, Combination; Female; Hemoglobins; Humans; Infant; Malaria; Malaria, Falciparum; Male; Parasitemia; Risk Factors | 2017 |
Malaria in Dielmo, a Senegal village: Is its elimination possible after seven years of implementation of long-lasting insecticide-treated nets?
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Artemisinins; Child; Child, Preschool; Cross-Sectional Studies; Humans; Infant; Insecticide-Treated Bednets; Longitudinal Studies; Malaria; Middle Aged; Mosquito Control; Outcome Assessment, Health Care; Recurrence; Risk Factors; Senegal; Socioeconomic Factors; Surveys and Questionnaires; Time Factors; Young Adult | 2017 |
Network meta-analysis including treatment by covariate interactions: Consistency can vary across covariate values.
Topics: Adolescent; Adult; Aged; Algorithms; Artemisinins; Bayes Theorem; Humans; Malaria; Middle Aged; Models, Statistical; Network Meta-Analysis; Odds Ratio; Probability; Research Design; Time Factors; Young Adult | 2017 |
Artemisia annua dried leaf tablets treated malaria resistant to ACT and i.v. artesunate: Case reports.
Topics: Administration, Intravenous; Adolescent; Adult; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisia annua; Artemisinins; Artesunate; Child; Child, Preschool; Drug Combinations; Drug Resistance, Microbial; Ethanolamines; Female; Fluorenes; Humans; Infant; Malaria; Male; Middle Aged; Plant Leaves; Tablets; Treatment Outcome; Young Adult | 2017 |
School-based diagnosis and treatment of malaria by teachers using rapid diagnostic tests and artemisinin-based combination therapy: experiences and perceptions of users and implementers of the Learner Treatment Kit, southern Malawi.
Topics: Artemisinins; Case Management; Diagnostic Tests, Routine; Drug Therapy, Combination; Health Knowledge, Attitudes, Practice; Malaria; Malawi; Perception; Randomized Controlled Trials as Topic; Schools | 2017 |
Artemisinin combination therapy mass drug administration in a setting of low malaria endemicity: programmatic coverage and adherence during an observational study in Zanzibar.
Topics: Antimalarials; Artemisinins; Drug Therapy, Combination; Humans; Malaria; Mass Drug Administration; Parasitemia; Tanzania; Treatment Adherence and Compliance | 2017 |
Preparation and in vivo evaluation of anti-plasmodial properties of artemisinin-loaded PCL-PEG-PCL nanoparticles.
Topics: Animals; Anti-Infective Agents; Artemisinins; Drug Carriers; Drug Evaluation, Preclinical; Female; Malaria; Mice; Nanoparticles; Plasmodium berghei; Polyesters; Polyethylene Glycols | 2018 |
Treatment-seeking patterns for malaria in pharmacies in five sub-Saharan African countries.
Topics: Adolescent; Adult; Africa South of the Sahara; Antimalarials; Artemisinins; Case Management; Child; Child, Preschool; Commerce; Diagnostic Tests, Routine; Drug Prescriptions; Drug Therapy, Combination; Female; Ghana; Health Care Sector; Humans; Kenya; Malaria; Male; Nigeria; Pharmacies; Private Sector; Surveys and Questionnaires; Tanzania; Uganda; Young Adult | 2017 |
Quantification of the antimalarial drug pyronaridine in whole blood using LC-MS/MS - Increased sensitivity resulting from reduced non-specific binding.
Topics: Antimalarials; Artemisinins; Chromatography, Liquid; Cross-Over Studies; Drug Interactions; Formates; Humans; Malaria; Naphthyridines; Sensitivity and Specificity; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2017 |
Antimalarial drugs available in the city Cabinda (Angola) in 2016.
Topics: Angola; Antimalarials; Artemisinins; Cities; Drug Costs; Drug Therapy, Combination; Health Services Accessibility; Humans; Malaria; Pharmacies; Private Sector; Urban Population | 2017 |
Population Pharmacokinetic and Pharmacodynamic Modeling of Artemisinin Resistance in Southeast Asia.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Drug Resistance; Female; Humans; Malaria; Male; Models, Biological; Nomograms; Young Adult | 2017 |
The use of respondent-driven sampling to assess malaria knowledge, treatment-seeking behaviours and preventive practices among mobile and migrant populations in a setting of artemisinin resistance in Western Cambodia.
Topics: Antimalarials; Artemisinins; Cambodia; Drug Resistance; Female; Health Behavior; Health Knowledge, Attitudes, Practice; Humans; Malaria; Male; Primary Prevention; Sampling Studies; Transients and Migrants | 2017 |
The contribution of malaria control interventions on spatio-temporal changes of parasitaemia risk in Uganda during 2009-2014.
Topics: Animals; Artemisinins; Child, Preschool; Culicidae; Female; Humans; Infant; Insecticide-Treated Bednets; Insecticides; Malaria; Male; Mosquito Control; Parasitemia; Spatio-Temporal Analysis; Uganda | 2017 |
In vivo and in vitro Models for Scanning Drug Substances in Malaria: Prestudy.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Disease Models, Animal; Drug Evaluation, Preclinical; In Vitro Techniques; Malaria; Male; Mice; Mice, Inbred BALB C; Plant Extracts; Plasmodium berghei; Tetracycline | 2017 |
Molecular markers for artemisinin and partner drug resistance in natural Plasmodium falciparum populations following increased insecticide treated net coverage along the slope of mount Cameroon: cross-sectional study.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Biomarkers; Cameroon; Child; Child, Preschool; Cross-Sectional Studies; Drug Combinations; Drug Resistance; Female; Humans; Infant; Insecticide-Treated Bednets; Malaria; Male; Middle Aged; Parasitemia; Plasmodium falciparum; Protozoan Proteins; Young Adult | 2017 |
Expanding malaria diagnosis and treatment in Lao PDR: lessons learned from a public-private mix initiative.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Child, Preschool; Diagnostic Tests, Routine; Drug Therapy, Combination; Female; Humans; Laos; Malaria; Male; Middle Aged; Public-Private Sector Partnerships; Young Adult | 2017 |
The malaria testing and treatment landscape in Kenya: results from a nationally representative survey among the public and private sector in 2016.
Topics: Antimalarials; Artemisinins; Case Management; Commerce; Disease Management; Humans; Kenya; Malaria; Pharmacies; Population Surveillance; Private Sector; Public Sector; Surveys and Questionnaires; Universal Health Insurance | 2017 |
Emergence of Nonfalciparum Plasmodium Infection Despite Regular Artemisinin Combination Therapy in an 18-Month Longitudinal Study of Ugandan Children and Their Mothers.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Longitudinal Studies; Malaria; Male; Middle Aged; Plasmodium; Risk Factors; Uganda; Young Adult | 2018 |
Liposomes of dimeric artesunate phospholipid: A combination of dimerization and self-assembly to combat malaria.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Dimerization; Drug Carriers; Drug Liberation; Female; Glycerylphosphorylcholine; Humans; Liposomes; Malaria; Mice, Inbred BALB C; Nanoparticles; Particle Size | 2018 |
An assessment of the malaria-related knowledge and practices of Tanzania's drug retailers: exploring the impact of drug store accreditation.
Topics: Accreditation; Antimalarials; Artemisinins; Commerce; Health Knowledge, Attitudes, Practice; Health Services Research; Humans; Malaria; Pharmacies; Private Sector; Qualitative Research; Tanzania | 2018 |
The effect of case management and vector-control interventions on space-time patterns of malaria incidence in Uganda.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Bayes Theorem; Case Management; Child; Child, Preschool; Drug Combinations; Humans; Incidence; Infant; Infant, Newborn; Malaria; Middle Aged; Mosquito Control; Plasmodium; Spatio-Temporal Analysis; Uganda; Young Adult | 2018 |
Combination of artemisinin-based natural compounds from Artemisia annua L. for the treatment of malaria: Pharmacodynamic and pharmacokinetic studies.
Topics: Animals; Antimalarials; Artemisia annua; Artemisinins; Malaria; Male; Mice; Plant Extracts | 2018 |
Level A in vitro-in vivo correlation: Application to establish a dissolution test for artemether and lumefantrine tablets.
Topics: Adolescent; Adult; Antimalarials; Artemether; Artemisinins; Ethanolamines; Female; Fluorenes; Humans; Lumefantrine; Malaria; Male; Middle Aged; Solubility; Tablets; Young Adult | 2018 |
A cryptic cycle in haematopoietic niches promotes initiation of malaria transmission and evasion of chemotherapy.
Topics: Animals; Antimalarials; Artemisinins; Disease Models, Animal; Drug Resistance; Female; Gametogenesis; Hematopoietic Stem Cells; Humans; Malaria; Mice; Mice, Inbred BALB C; Plasmodium berghei; Reproduction, Asexual; Reticulocytes; Stem Cell Niche | 2018 |
Caregivers' compliance with referral advice: evidence from two studies introducing mRDTs into community case management of malaria in Uganda.
Topics: Adolescent; Antimalarials; Artemisinins; Artesunate; Caregivers; Case Management; Child; Child, Preschool; Community Health Workers; Diagnostic Tests, Routine; Female; Guideline Adherence; Humans; Infant; Malaria; Male; Randomized Controlled Trials as Topic; Referral and Consultation; Treatment Adherence and Compliance; Uganda | 2018 |
The decline of malaria in Vietnam, 1991-2014.
Topics: Antimalarials; Artemisinins; Case Management; Incidence; Malaria; Mosquito Control; Plasmodium; Vietnam | 2018 |
Efficacy of artemisinin-based combination therapies and prevalence of molecular markers associated with artemisinin, piperaquine and sulfadoxine-pyrimethamine resistance in Sierra Leone.
Topics: Antimalarials; Artemisinins; Child, Preschool; Drug Resistance; Drug Therapy, Combination; Female; Humans; Infant; Malaria; Male; Mutation; Quinolines; Sulfadoxine; Tetrahydrofolate Dehydrogenase | 2018 |
Misuse of Artemisinin Combination Therapies by Clients of Medicine Retailers Suspected to Have Malaria Without Prior Parasitological Confirmation in Nigeria.
Topics: Adult; Antimalarials; Artemisinins; Cross-Sectional Studies; Drug Misuse; Drug Therapy, Combination; Female; Humans; Malaria; Male; Middle Aged; Nigeria; Pharmacies; Young Adult | 2018 |
How to defuse malaria's ticking time bomb.
Topics: Animals; Armed Conflicts; Artemisinins; Cambodia; Culicidae; Drug Resistance; Female; Foundations; Global Health; Humans; Malaria; Male; Myanmar; Plasmodium falciparum | 2018 |
Targeted Nanostructured Lipid Carrier for Brain Delivery of Artemisinin: Design, Preparation, Characterization, Optimization and Cell Toxicity.
Topics: Antimalarials; Antineoplastic Agents; Artemisinins; Brain; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Carriers; Drug Delivery Systems; Drug Design; Drug Screening Assays, Antitumor; Humans; Lipids; Malaria; Nanostructures; Parasitic Sensitivity Tests; Particle Size; Structure-Activity Relationship; Transferrin | 2018 |
Challenges of achieving sustainable community health services for community case management of malaria.
Topics: Adult; Artemisinins; Case Management; Child, Preschool; Community Health Services; Community Health Workers; Equipment and Supplies; Female; Focus Groups; Humans; Infant; Kenya; Malaria; Middle Aged; Mothers; Pregnancy; Program Evaluation; Qualitative Research; Stakeholder Participation | 2018 |
Development of an agent-based model to assess the impact of substandard and falsified anti-malarials: Uganda case study.
Topics: Antimalarials; Artemisinins; Child, Preschool; Counterfeit Drugs; Drug Resistance; Female; Humans; Infant; Malaria; Male; Models, Theoretical; Private Sector; Uganda | 2019 |
Evaluation of the effects on the QT-interval of 4 artemisinin-based combination therapies with a correction-free and heart rate-free method.
Topics: Adolescent; Amodiaquine; Antimalarials; Arrhythmias, Cardiac; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Child, Preschool; Drug Combinations; Ethanolamines; Female; Fluorenes; Heart Rate; Humans; Long QT Syndrome; Malaria; Malaria, Falciparum; Male; Quinolines; Young Adult | 2019 |
Effectiveness of antimalarial interventions in Nigeria: Evidence from facility-level longitudinal data.
Topics: Antimalarials; Artemisinins; Case Management; Drug Therapy, Combination; Government Programs; Health Education; Health Workforce; Humans; Insecticide-Treated Bednets; Longitudinal Studies; Malaria; Models, Econometric; Nigeria; Reagent Kits, Diagnostic | 2019 |
AaPP2C1 negatively regulates the expression of genes involved in artemisinin biosynthesis through dephosphorylating AaAPK1.
Topics: Abscisic Acid; Arabidopsis Proteins; Artemisia annua; Artemisinins; Gene Expression Regulation, Plant; Humans; Malaria; Phosphorylation; Phosphotransferases; Plant Leaves; Plants, Genetically Modified; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Transcription Factors | 2019 |
A Temporizing Solution to "Artemisinin Resistance".
Topics: Antimalarials; Artemisinins; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Parasitemia; Plasmodium | 2019 |
Malaria today: advances in management and control.
Topics: Antimalarials; Artemisinins; Drug Discovery; Drug Resistance; Global Health; Humans; Malaria; Malaria Vaccines; Mosquito Control; Plasmodium | 2019 |
Quality of Malaria Case Management and Reporting at Public Health Facilities in Six Health Districts in Guinea, 2018.
Topics: Adolescent; Antimalarials; Artemisinins; Case Management; Child; Child, Preschool; Diagnostic Tests, Routine; Drug Therapy, Combination; Female; Guinea; Health Facilities; Humans; Infant; Malaria; Male; Public Health | 2019 |
Malaria morbidity and mortality following introduction of a universal policy of artemisinin-based treatment for malaria in Papua, Indonesia: A longitudinal surveillance study.
Topics: Antimalarials; Artemisinins; Drug Resistance, Multiple; Humans; Incidence; Indonesia; Longitudinal Studies; Malaria; Population Surveillance; Program Evaluation; Prospective Studies; Risk Factors; Time Factors; Treatment Outcome | 2019 |
Challenges and perceptions of implementing mass testing, treatment and tracking in malaria control: a qualitative study in Pakro sub-district of Ghana.
Topics: Adult; Anti-Infective Agents; Artemisinins; Child; Child, Preschool; Feasibility Studies; Female; Focus Groups; Ghana; Health Personnel; Health Plan Implementation; Health Services Accessibility; Humans; Infection Control; Malaria; Male; Mass Screening; Parasitemia; Perception; Qualitative Research | 2019 |
[Adherence of private sector providers to uncomplicated malaria management policy in Madagascar].
Topics: Antimalarials; Artemisinins; Cross-Sectional Studies; Diagnostic Tests, Routine; Drug Therapy, Combination; Guideline Adherence; Humans; Madagascar; Malaria; Practice Guidelines as Topic; Private Sector; Retrospective Studies | 2019 |
Artemisinin-(Iso)quinoline Hybrids by C-H Activation and Click Chemistry: Combating Multidrug-Resistant Malaria.
Topics: Animals; Antimalarials; Artemisinins; Click Chemistry; Drug Resistance, Multiple; Humans; Isoquinolines; Malaria; Mice; Plasmodium | 2019 |
Retrospective Comparison of 2 Management Strategies for Perioperative Malaria Episodes in Pediatric Patients in a Limited-Resource Setting.
Topics: Adolescent; Age Factors; Antimalarials; Artemisinins; Child; Child, Preschool; Cleft Lip; Cleft Palate; Clinical Protocols; Developing Countries; Drug Administration Schedule; Elective Surgical Procedures; Female; Health Resources; Humans; Incidence; Infant; Malaria; Male; Nigeria; Oral Surgical Procedures; Perioperative Care; Prevalence; Retrospective Studies; Risk Factors; Time Factors; Treatment Outcome | 2019 |
Leveraging crowdsourcing to accelerate global health solutions.
Topics: Antimalarials; Artemisinins; Crowdsourcing; Global Health; Humans; Malaria | 2019 |
The impact of artemisinin combination therapy and long-lasting insecticidal nets on forest malaria incidence in tribal villages of India, 2006-2011.
Topics: Adolescent; Antimalarials; Artemisinins; Child; Child, Preschool; Female; Humans; India; Infant; Infant, Newborn; Insecticide-Treated Bednets; Malaria; Male; Mosquito Control; Plasmodium; Trees; Young Adult | 2013 |
The quest for affordable artemisinin.
Topics: Animals; Antimalarials; Artemisia annua; Artemisinins; Chemistry Techniques, Synthetic; Drug Costs; Humans; Malaria; Plasmodium | 2013 |
Malaria burden and artemisinin resistance in the mobile and migrant population on the Thai-Myanmar border, 1999-2011: an observational study.
Topics: Antimalarials; Artemisinins; Artesunate; Climate; Community Health Workers; Cross-Sectional Studies; Drug Resistance; Female; Geography; Hospitalization; Humans; Malaria; Mefloquine; Myanmar; Plasmodium falciparum; Plasmodium vivax; Pregnancy; Pregnancy Complications, Parasitic; Prevalence; Rain; Reproducibility of Results; Temperature; Thailand; Transients and Migrants | 2013 |
Artemisinin-based combination therapy: knowledge and perceptions of patent medicine dealers in Owerri Metropolis, Imo State, Nigeria and implications for compliance with current malaria treatment protocol.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Cross-Sectional Studies; Drug Therapy, Combination; Educational Status; Female; Health Knowledge, Attitudes, Practice; Humans; Malaria; Male; Medication Adherence; Middle Aged; Nigeria; Pharmacies; Young Adult | 2013 |
Implementation of the Affordable Medicines for Malaria Facility (AMFm) in Ghana: processes, challenges and achievements.
Topics: Antimalarials; Artemisinins; Cooperative Behavior; Drug Therapy, Combination; Ghana; Health Education; Health Promotion; Health Services Accessibility; Humans; International Agencies; International Cooperation; Malaria; Private Sector; Public Sector | 2013 |
Safety of Artemisinin-Based Combination Therapies in Nigeria: A Cohort Event Monitoring Study.
Topics: Adolescent; Adult; Amodiaquine; Anti-Infective Agents; Antimalarials; Artemisinins; Child; Child, Preschool; Cohort Studies; Ethanolamines; Female; Fluorenes; Humans; Infant; Infant, Newborn; Lumefantrine; Malaria; Male; Nigeria; Pregnancy; Prospective Studies; Young Adult | 2013 |
Artemisinin-based combination therapy availability and use in the private sector of five AMFm phase 1 countries.
Topics: Africa; Artemisinins; Drug Therapy, Combination; Health Services Accessibility; Humans; Interviews as Topic; Malaria; Pharmacies; Private Sector; Program Evaluation; Surveys and Questionnaires | 2013 |
Made in Europe: will artemisinin resistance emerge in French Guiana?
Topics: Antimalarials; Artemisinins; Drug Resistance; Europe; French Guiana; Health Policy; Humans; Malaria | 2013 |
Access to artemisinin-based anti-malarial treatment and its related factors in rural Tanzania.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Therapy, Combination; Female; Health Services Accessibility; Humans; Infant; Infant, Newborn; Interviews as Topic; Malaria; Male; Middle Aged; Rural Population; Tanzania; Young Adult | 2013 |
Measuring coverage in MNCH: accuracy of measuring diagnosis and treatment of childhood malaria from household surveys in Zambia.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Caregivers; Chi-Square Distribution; Child Health Services; Child, Preschool; Cross-Sectional Studies; Developing Countries; Drug Therapy, Combination; Family Characteristics; Female; Health Care Surveys; Health Knowledge, Attitudes, Practice; Health Services Research; Humans; Infant; Infant, Newborn; Malaria; Male; Mental Recall; Middle Aged; Parasitology; Predictive Value of Tests; Program Evaluation; Reproducibility of Results; Research Design; Surveys and Questionnaires; Time Factors; Treatment Outcome; Young Adult; Zambia | 2013 |
Probabilistic record linkage for monitoring the safety of artemisinin-based combination therapy in the first trimester of pregnancy in Senegal.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anti-Infective Agents; Artemisinins; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Malaria; Medical Record Linkage; Middle Aged; Pregnancy; Pregnancy Complications, Parasitic; Pregnancy Outcome; Pregnancy Trimester, First; Senegal; Young Adult | 2013 |
Differential interactions of the broad spectrum drugs artemisinin, dihydroartemisinin and artesunate with serum albumin.
Topics: Animals; Artemisinins; Artesunate; Cattle; Drug Therapy, Combination; Hydrophobic and Hydrophilic Interactions; Malaria; Protein Binding; Serum Albumin | 2013 |
Correlation between Plasmodium yoelii nigeriensis susceptibility to artemisinin and alkylation of heme by the drug.
Topics: Alkylation; Animals; Antimalarials; Artemisinins; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Resistance; Erythrocytes; Female; Heme; Malaria; Mice; Plasmodium yoelii; Protein Binding; Spleen | 2013 |
Access to subsidized ACT and malaria treatment--evidence from the first year of the AMFm program in six districts in Uganda.
Topics: Adult; Anti-Bacterial Agents; Antimalarials; Artemisinins; Child; Drug Costs; Drug Therapy, Combination; Female; Financing, Government; Health Services Accessibility; Humans; Malaria; Male; Private Sector; Uganda | 2014 |
Adverse drug events resulting from use of drugs with sulphonamide-containing anti-malarials and artemisinin-based ingredients: findings on incidence and household costs from three districts with routine demographic surveillance systems in rural Tanzania.
Topics: Antimalarials; Artemisinins; Child, Preschool; Cross-Sectional Studies; Drug-Related Side Effects and Adverse Reactions; Family Characteristics; Female; Health Care Costs; Humans; Incidence; Infant; Malaria; Male; Rural Population; Sulfonamides; Tanzania | 2013 |
An endoperoxide-based hybrid approach to deliver falcipain inhibitors inside malaria parasites.
Topics: Antimalarials; Artemisinins; Binding Sites; Chloroquine; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Drug Resistance; Erythrocytes; Ferrous Compounds; Hemoglobins; Humans; Malaria; Molecular Docking Simulation; Plasmodium falciparum; Protein Structure, Tertiary; Structure-Activity Relationship; Sulfones; Tetraoxanes | 2013 |
Disrupting malaria parasite AMA1-RON2 interaction with a small molecule prevents erythrocyte invasion.
Topics: Animals; Antimalarials; Artemisinins; Erythrocytes; Humans; Inhibitory Concentration 50; Malaria; Merozoites; Parasites; Plasmodium falciparum; Protein Binding; Protein Kinase Inhibitors; Protozoan Proteins; Small Molecule Libraries; src-Family Kinases | 2013 |
Do price subsidies on artemisinin combination therapy for malaria increase household use? Evidence from a repeated cross-sectional study in remote regions of Tanzania.
Topics: Antimalarials; Artemisinins; Cross-Sectional Studies; Drug Therapy, Combination; Geography; Health Services Accessibility; Humans; Malaria; Tanzania | 2013 |
The impact of heterogeneous transmission on the establishment and spread of antimalarial drug resistance.
Topics: Animals; Antimalarials; Artemisinins; Computer Simulation; Culicidae; Drug Resistance; Humans; Malaria; Models, Statistical; Plasmodium falciparum; Poisson Distribution; Stochastic Processes; Time Factors | 2014 |
Sperm characteristics, antioxidant status and hormonal profile in rats treated with artemisinin.
Topics: 5'-Nucleotidase; Animals; Antimalarials; Antioxidants; Artemisinins; Body Weight; Drug Evaluation, Preclinical; Fertility; Genitalia, Male; Malaria; Male; Oxidative Stress; Phytotherapy; Plant Extracts; Random Allocation; Rats, Wistar; Sperm Count; Spermatozoa | 2014 |
Simulated digestion of dried leaves of Artemisia annua consumed as a treatment (pACT) for malaria.
Topics: Antimalarials; Artemisia annua; Artemisinins; Biological Availability; Capsules; Dietary Supplements; Digestion; Edible Grain; Flavonoids; Food-Drug Interactions; Gastric Mucosa; Intestinal Mucosa; Malaria; Plant Leaves; Plant Oils; Sucrose | 2014 |
Diffusion of subsidized ACTs in accredited drug shops in Tanzania: determinants of stocking and characteristics of early and late adopters.
Topics: Accreditation; Antimalarials; Artemisinins; Economic Competition; Financing, Government; Health Services Needs and Demand; Humans; Malaria; Pharmacies; Tanzania | 2013 |
[Malaria].
Topics: Antimalarials; Artemisinins; Artesunate; Atovaquone; Drug Therapy, Combination; Humans; Malaria; Prevalence; Proguanil | 2014 |
Scale-up of malaria rapid diagnostic tests and artemisinin-based combination therapy: challenges and perspectives in sub-Saharan Africa.
Topics: Africa South of the Sahara; Antimalarials; Artemisinins; Delivery of Health Care; Diagnostic Tests, Routine; Drug Combinations; Health Knowledge, Attitudes, Practice; Health Policy; Humans; Malaria | 2014 |
Realistically, how far are we from a universal malaria drug?
Topics: Antimalarials; Artemisinins; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Malaria; Plasmodium; Primaquine; Recurrence | 2014 |
The survival times of malaria-infected mice are prolonged more by several new two-carbon-linked artemisinin-derived dimer carbamates than by the trioxane antimalarial drug artemether.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Carbamates; Carbon; Crystallography, X-Ray; Dimerization; Drug Therapy, Combination; Malaria; Mefloquine; Mice; Molecular Conformation; Plasmodium berghei; Structure-Activity Relationship; Survival Analysis | 2014 |
What determines providers' stated preference for the treatment of uncomplicated malaria?
Topics: Antimalarials; Artemisinins; Attitude of Health Personnel; Cameroon; Drug Therapy, Combination; Health Facilities; Health Personnel; Humans; Malaria; Models, Econometric; Multilevel Analysis; Nigeria; Pharmacies; Practice Guidelines as Topic; Practice Patterns, Physicians' | 2014 |
Quality of malaria case management in Malawi: results from a nationally representative health facility survey.
Topics: Adolescent; Artemisinins; Case Management; Child; Child, Preschool; Data Collection; Female; Health Facilities; Health Personnel; Humans; Infant; Malaria; Malawi; Male; Quality of Health Care | 2014 |
Malaria and natural products: what is the future of this long-lasting relationship?
Topics: Antimalarials; Artemisinins; Biological Products; Humans; Malaria; Plasmodium falciparum | 2014 |
Pharmacokinetics of artemisinin delivered by oral consumption of Artemisia annua dried leaves in healthy vs. Plasmodium chabaudi-infected mice.
Topics: Administration, Oral; Animals; Antimalarials; Artemisia annua; Artemisinins; Malaria; Male; Mice, Inbred C57BL; Plant Leaves; Plasmodium chabaudi | 2014 |
Awareness of antimalarial policy and use of artemisinin-based combination therapy for malaria treatment in communities of two selected local government areas of Ogun State, Nigeria.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Awareness; Child, Preschool; Cross-Sectional Studies; Drug Therapy, Combination; Female; Health Knowledge, Attitudes, Practice; Health Policy; Health Services Accessibility; Humans; Infant; Infant, Newborn; Malaria; Nigeria; Pregnancy; Socioeconomic Factors | 2014 |
Prevalence of malaria parasitemia and purchase of artemisinin-based combination therapies (ACTs) among drug shop clients in two regions in Tanzania with ACT subsidies.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Child, Preschool; Demography; Drug Therapy, Combination; Female; Geography; Health Planning Support; Humans; Malaria; Male; Parasitemia; Patient Acceptance of Health Care; Pharmacies; Prevalence; Tanzania; Young Adult | 2014 |
Time to contain artemisinin resistance.
Topics: Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria | 2014 |
Malaria: a molecular marker of artemisinin resistance.
Topics: Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria | 2014 |
Antimalarial chemotherapy: artemisinin-derived dimer carbonates and thiocarbonates.
Topics: Animals; Antimalarials; Artemisinins; Carbonates; Dimerization; Disease Models, Animal; Dose-Response Relationship, Drug; Malaria; Male; Mice; Mice, Inbred C57BL; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium berghei; Structure-Activity Relationship; Sulfhydryl Compounds | 2014 |
The rise and fall of malaria in a West African rural community, Dielmo, Senegal, from 1990 to 2012: a 22 year longitudinal study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Anopheles; Antimalarials; Artemisinins; Child; Child, Preschool; Cross-Sectional Studies; Drug Therapy, Combination; Humans; Infant; Infant, Newborn; Insect Vectors; Longitudinal Studies; Malaria; Middle Aged; Plasmodium falciparum; Plasmodium malariae; Plasmodium ovale; Prevalence; Prospective Studies; Rural Population; Senegal; Young Adult | 2014 |
Has Tanzania embraced the green leaf? Results from outlet and household surveys before and after implementation of the Affordable Medicines Facility-malaria.
Topics: Antimalarials; Artemisinins; Drug Costs; Family Characteristics; Health Services Accessibility; Health Surveys; Humans; Malaria; Pharmacies; Private Sector; Program Evaluation; Public Sector; Surveys and Questionnaires; Tanzania | 2014 |
[Diagnosis and treatment for three imported Plasmodium malariae malaria cases in Henan Province].
Topics: Artemisinins; Humans; Malaria; Microscopy; Polymerase Chain Reaction | 2014 |
Spatial distribution, work patterns, and perception towards malaria interventions among temporary mobile/migrant workers in artemisinin resistance containment zone.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Child, Preschool; Cross-Sectional Studies; Drug Resistance; Family Characteristics; Female; Geographic Mapping; Health Knowledge, Attitudes, Practice; Health Services Accessibility; Humans; Insecticide-Treated Bednets; Malaria; Male; Myanmar; Patient Acceptance of Health Care; Perception; Prospective Studies; Transients and Migrants; Work; Young Adult | 2014 |
Severe malaria not responsive to artemisinin derivatives in man returning from Angola to Vietnam.
Topics: Angola; Antimalarials; Artemisinins; Clindamycin; Drug Therapy, Combination; Humans; Malaria; Male; Middle Aged; Vietnam | 2014 |
QSAR and docking based semi-synthesis and in vivo evaluation of artemisinin derivatives for antimalarial activity.
Topics: Animals; Antimalarials; Artemisinins; Aspartic Acid Endopeptidases; Binding Sites; Biological Availability; Computer-Aided Design; Disease Models, Animal; Drug Design; Magnetic Resonance Spectroscopy; Malaria; Mice; Molecular Docking Simulation; Plasmodium yoelii; Protozoan Proteins; Quantitative Structure-Activity Relationship | 2014 |
Management of febrile children under five years in hospitals and health centres of rural Ghana.
Topics: Anti-Bacterial Agents; Antimalarials; Artemisinins; Caregivers; Child Health Services; Child, Preschool; Community Health Services; Cross-Sectional Studies; Delivery of Health Care; Disease Management; Drug Therapy, Combination; Drug Utilization; Female; Fever; Ghana; Health Literacy; Hospitals, Rural; Humans; Infant; Infant, Newborn; Insurance Coverage; Malaria; Male; Medical Audit; Rural Population; Sampling Studies; Socioeconomic Factors | 2014 |
Chloroquine remains effective for treating Plasmodium vivax malaria in Pursat province, Western Cambodia.
Topics: Anti-Infective Agents; Artemisinins; Cambodia; Chloroquine; Drug Resistance; Malaria; Plasmodium vivax | 2014 |
Access to artemisinin-based combination therapy (ACT) and quinine in malaria holoendemic regions of western Kenya.
Topics: Adult; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Cross-Sectional Studies; Drug Combinations; Ethanolamines; Fluorenes; Health Services Accessibility; Humans; Kenya; Malaria; Quinine | 2014 |
In search of next generation antimalarials.
Topics: Animals; Antimalarials; Artemisinins; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Discovery; Macaca mulatta; Malaria; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium; Structure-Activity Relationship | 2014 |
Improving access to malaria medicine through private-sector subsidies in seven African countries.
Topics: Africa; Antimalarials; Artemisinins; Cluster Analysis; Commerce; Developing Countries; Drug Resistance; Health Services Accessibility; Humans; Malaria; Quality Improvement | 2014 |
Genetic mutations in Plasmodium falciparum and Plasmodium vivax dihydrofolate reductase (DHFR) and dihydropteroate synthase (DHPS) in Vanuatu and Solomon Islands prior to the introduction of artemisinin combination therapy.
Topics: Antimalarials; Artemisinins; Cross-Sectional Studies; Dihydropteroate Synthase; Dried Blood Spot Testing; Drug Combinations; Drug Therapy, Combination; Genetic Markers; Humans; Malaria; Melanesia; Mutation; Plasmodium falciparum; Plasmodium vivax; Pyrimethamine; Sulfadoxine; Tetrahydrofolate Dehydrogenase; Vanuatu | 2014 |
Presumptive treatment of malaria from formal and informal drug vendors in Nigeria.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Black People; Commerce; Drug Therapy, Combination; Female; Health Behavior; Humans; Logistic Models; Malaria; Male; Middle Aged; Nigeria; Nonprescription Drugs; Young Adult | 2014 |
Cytochrome P450 single nucleotide polymorphisms in an indigenous Tanzanian population: a concern about the metabolism of artemisinin-based combinations.
Topics: Adult; Antimalarials; Artemisinins; Cross-Sectional Studies; Cytochrome P-450 Enzyme System; Female; Gene Frequency; Humans; Malaria; Male; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Tanzania; Young Adult | 2014 |
Genomics illuminates parasite biology.
Topics: Animals; Anti-Infective Agents; Artemisinins; Drug Resistance; Genome, Protozoan; Genomics; Humans; Malaria; Mutation; Plasmodium; Protozoan Proteins | 2014 |
Patterns and predictors of malaria care-seeking, diagnostic testing, and artemisinin-based combination therapy for children under five with fever in Northern Nigeria: a cross-sectional study.
Topics: Antimalarials; Artemisinins; Child, Preschool; Cross-Sectional Studies; Drug Therapy, Combination; Female; Fever; Humans; Infant; Infant, Newborn; Malaria; Male; Nigeria; Patient Acceptance of Health Care | 2014 |
Stage specific activity of synthetic antimalarial endoperoxides, N-89 and N-251, against Plasmodium falciparum.
Topics: Animals; Antimalarials; Artemisinins; Drug Resistance, Multiple; Erythrocytes; Heterocyclic Compounds, 2-Ring; Humans; Malaria; Parasitic Sensitivity Tests; Plasmodium falciparum; Spiro Compounds; Tetraoxanes; Trophozoites | 2015 |
Core concept: Synthetic biology-change, accelerated.
Topics: Artemisinins; Biomedical Engineering; Genetic Engineering; Humans; Malaria; Synthetic Biology; Tissue Engineering | 2014 |
Antimalarial chemotherapy: orally curative artemisinin-derived trioxane dimer esters.
Topics: Administration, Oral; Animals; Antimalarials; Artemisinins; Dimerization; Malaria; Mice; Plasmodium berghei | 2015 |
Drug resistance. Population transcriptomics of human malaria parasites reveals the mechanism of artemisinin resistance.
Topics: Animals; Antimalarials; Artemisinins; Chaperonin Containing TCP-1; Drug Resistance; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum; Transcriptome; Unfolded Protein Response | 2015 |
Infectious diseases. Understanding artemisinin resistance.
Topics: Animals; Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum; Protozoan Proteins; Unfolded Protein Response | 2015 |
Measuring the association between artemisinin-based case management and malaria incidence in southern Vietnam, 1991-2010.
Topics: Animals; Anti-Infective Agents; Artemisinins; Case Management; Confidence Intervals; Culicidae; Humans; Incidence; Insect Vectors; Insecticide-Treated Bednets; Malaria; Models, Statistical; Mosquito Control; Plasmodium; Vietnam | 2015 |
Adherence and uptake of artemisinin-based combination treatments for uncomplicated malaria: a qualitative study in northern Ghana.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Drug Therapy, Combination; Female; Ghana; Health Facilities; Health Knowledge, Attitudes, Practice; Humans; Malaria; Male; Medication Adherence; Young Adult | 2015 |
Improving uptake and use of malaria rapid diagnostic tests in the context of artemisinin drug resistance containment in eastern Myanmar: an evaluation of incentive schemes among informal private healthcare providers.
Topics: Antimalarials; Artemisinins; Drug Resistance; Female; Health Personnel; Humans; Malaria; Male; Middle Aged; Myanmar; Parasitology; Private Practice; Reagent Kits, Diagnostic; Reimbursement, Incentive | 2015 |
Anti-malarial prescribing practices in Sudan eight years after introduction of artemisinin-based combination therapies and implications for development of drug resistance.
Topics: Antimalarials; Artemisinins; Cross-Sectional Studies; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Medication Errors; Practice Patterns, Physicians'; Sudan | 2015 |
Utilization of community health workers for malaria treatment: results from a three-year panel study in the districts of Kaya and Zorgho, Burkina Faso.
Topics: Antimalarials; Artemisinins; Burkina Faso; Case Management; Child, Preschool; Community Health Workers; Drug Combinations; Female; Humans; Infant; Longitudinal Studies; Malaria; Male | 2015 |
Screening and Treating UN Peacekeepers to Prevent the Introduction of Artemisinin-Resistant Malaria into Africa.
Topics: Adult; Anti-Infective Agents; Artemisinins; Drug Resistance, Microbial; Humans; Malaria; Military Personnel; United Nations | 2015 |
Prices and mark-ups on antimalarials: evidence from nationally representative studies in six malaria-endemic countries.
Topics: Africa; Antimalarials; Artemisinins; Cambodia; Commerce; Drug Industry; Drug Therapy, Combination; Global Health; Health Services Accessibility; Humans; Malaria; Private Sector; Surveys and Questionnaires | 2016 |
Effect of diagnostic testing on medicines used by febrile children less than five years in 12 malaria-endemic African countries: a mixed-methods study.
Topics: Africa South of the Sahara; Anti-Bacterial Agents; Antimalarials; Artemisinins; Child, Preschool; Diagnostic Tests, Routine; Drug Combinations; Female; Fever; Humans; Infant; Infant, Newborn; Logistic Models; Malaria; Male; Risk; Seasons; Socioeconomic Factors | 2015 |
Implications of Glutathione Levels in the Plasmodium berghei Response to Chloroquine and Artemisinin.
Topics: Animals; Artemisinins; Chloroquine; Drug Resistance; Glutamate-Cysteine Ligase; Glutathione; Malaria; Mice; Plasmodium berghei; Protozoan Proteins | 2015 |
[Malaria and HIV: which interactions?].
Topics: Adult; Animals; Antimalarials; Artemisinins; Coinfection; Female; HIV Infections; Humans; Insect Bites and Stings; Malaria; Travel | 2015 |
Availability and quality of anti-malarials among private sector outlets in Myanmar in 2012: results from a large, community-based, cross-sectional survey before a large-scale intervention.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Commerce; Cross-Sectional Studies; Humans; Malaria; Middle Aged; Myanmar; Pharmacies; Private Sector; Young Adult | 2015 |
Myanmar ministers and opposition leaders agree plan to eliminate malaria by 2030.
Topics: Antimalarials; Artemisinins; Disease Eradication; Drug Resistance, Multiple; Health Planning; Humans; Interprofessional Relations; Malaria; Myanmar; Politics | 2015 |
Seasonality in malaria transmission: implications for case-management with long-acting artemisinin combination therapy in sub-Saharan Africa.
Topics: Antimalarials; Artemisinins; Child; Child, Preschool; Cross-Sectional Studies; Drug Therapy, Combination; Humans; Incidence; Malaria; Seasons | 2015 |
Prompt access to effective malaria treatment among children under five in sub-Saharan Africa: a multi-country analysis of national household survey data.
Topics: Africa South of the Sahara; Antimalarials; Artemisinins; Child, Preschool; Cross-Sectional Studies; Drug Therapy, Combination; Female; Fever; Humans; Infant; Infant, Newborn; Malaria; Male; Time-to-Treatment | 2015 |
Novel Cross-Border Approaches to Optimise Identification of Asymptomatic and Artemisinin-Resistant Plasmodium Infection in Mobile Populations Crossing Cambodian Borders.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Asymptomatic Infections; Cambodia; Carrier State; Drug Resistance; Emigration and Immigration; Female; Humans; Laos; Malaria; Male; Plasmodium; Plasmodium falciparum; Plasmodium malariae; Plasmodium vivax; Risk Factors; Thailand; Transients and Migrants; Vietnam; Young Adult | 2015 |
Mobility dynamics of migrant workers and their socio-behavioral parameters related to malaria in Tier II, Artemisinin Resistance Containment Zone, Myanmar.
Topics: Adolescent; Adult; Artemisinins; Awareness; Child; Child, Preschool; Cross-Sectional Studies; Drug Resistance; Emigration and Immigration; Employment; Female; Health Knowledge, Attitudes, Practice; Health Services Accessibility; Humans; Insecticide-Treated Bednets; Malaria; Male; Myanmar; Population Dynamics; Pregnancy; Prospective Studies; Transients and Migrants; Young Adult | 2015 |
Design, implementation and evaluation of a training programme for school teachers in the use of malaria rapid diagnostic tests as part of a basic first aid kit in southern Malawi.
Topics: Antimalarials; Artemisinins; Child; Diagnostic Techniques and Procedures; Drug Therapy, Combination; Faculty; Female; First Aid; Humans; Inservice Training; Malaria; Malawi; Male | 2015 |
Induction of Multidrug Tolerance in Plasmodium falciparum by Extended Artemisinin Pressure.
Topics: Antimalarials; Artemisinins; Asia, Southeastern; Drug Tolerance; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum | 2015 |
Anti-parasite drugs sweep Nobel prize in medicine 2015.
Topics: Animals; Antimalarials; Antiparasitic Agents; Artemisinins; History, 20th Century; Humans; Ivermectin; Malaria; Medicine; Nobel Prize | 2015 |
NOBEL PRIZES. Neglected tropical diseases get the limelight in Stockholm.
Topics: Antimalarials; Artemisinins; China; Humans; Malaria; Medicine, Chinese Traditional; Neglected Diseases; Nobel Prize; Onchocerciasis, Ocular; Tropical Medicine | 2015 |
Feasibility and cost of using mobile phones for capturing drug safety information in peri-urban settlement in Ghana: a prospective cohort study of patients with uncomplicated malaria.
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Antimalarials; Artemisinins; Cell Phone; Child; Child, Preschool; Drug Therapy, Combination; Female; Ghana; Health Care Costs; Humans; Infant; Infant, Newborn; Malaria; Male; Prospective Studies; Suburban Population; Young Adult | 2015 |
Impact of chrysosplenetin on the pharmacokinetics and anti-malarial efficacy of artemisinin against Plasmodium berghei as well as in vitro CYP450 enzymatic activities in rat liver microsome.
Topics: Animals; Antimalarials; Artemisinins; Chromatography, Liquid; Cytochrome P-450 Enzyme System; Drug Synergism; Enzyme Inhibitors; Female; Flavonoids; Malaria; Male; Mice; Microsomes, Liver; Plasma; Plasmodium berghei; Rats, Sprague-Dawley; Tandem Mass Spectrometry; Treatment Outcome | 2015 |
Prevalence of asymptomatic malaria infection and use of different malaria control measures among primary school children in Morogoro Municipality, Tanzania.
Topics: Adolescent; Age Factors; Anemia; Antimalarials; Artemisinins; Asymptomatic Infections; Child; Cross-Sectional Studies; Drug Combinations; Female; Humans; Insecticide-Treated Bednets; Malaria; Male; Prevalence; Schools; Tanzania | 2015 |
Assessment of the safety of antimalarial drug use during early pregnancy (ASAP): protocol for a multicenter prospective cohort study in Burkina Faso, Kenya and Mozambique.
Topics: Antimalarials; Artemisinins; Clinical Protocols; Cohort Studies; Drug Administration Schedule; Female; Gestational Age; Humans; Infant, Newborn; Malaria; Maternal-Fetal Exchange; Patient Selection; Pharmacovigilance; Pregnancy; Pregnancy Complications, Parasitic; Pregnancy Outcome; Pregnancy Trimester, First; Prenatal Exposure Delayed Effects; Prospective Studies; Research Design; Sample Size | 2015 |
Stearylamine Liposomal Delivery of Monensin in Combination with Free Artemisinin Eliminates Blood Stages of Plasmodium falciparum in Culture and P. berghei Infection in Murine Malaria.
Topics: Amines; Animals; Antimalarials; Artemisinins; Blood; Drug Delivery Systems; Drug Therapy, Combination; Female; Liposomes; Malaria; Mice; Monensin; Plasmodium berghei; Plasmodium falciparum; Tissue Distribution | 2015 |
The discovery of Qinghaosu (artemisinin) as an effective anti-malaria drug: A unique China story.
Topics: Animals; Antimalarials; Artemisinins; China; Drug Discovery; History, 20th Century; History, 21st Century; Humans; Malaria; Medicine, Chinese Traditional; Plasmodium | 2016 |
Nobel Parasites in the Kingdom of Invertebrates.
Topics: Animals; Artemisinins; Drug Discovery; Host-Parasite Interactions; Humans; Immunity, Innate; Malaria; Nematode Infections; Nobel Prize; Physiology | 2016 |
Evaluation of the behaviour change communication and community mobilization activities in Myanmar artemisinin resistance containment zones.
Topics: Antimalarials; Artemisinins; Behavior Therapy; Cross-Sectional Studies; Disease Transmission, Infectious; Female; Health Communication; Health Services Research; Humans; Malaria; Male; Myanmar | 2015 |
Identification of Compounds with Efficacy against Malaria Parasites from Common North American Plants.
Topics: Animals; Antimalarials; Artemisinins; Drug Resistance; Glycosides; HeLa Cells; Humans; Malaria; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plants, Medicinal; Plasmodium falciparum; Quinine; Triterpenes; United States | 2016 |
A Brief History of Qinghaosu.
Topics: Africa; Antimalarials; Artemisia annua; Artemisinins; Asia; History, 20th Century; History, 21st Century; Humans; Malaria; Nobel Prize; Plant Extracts | 2015 |
Dispute delays release of malaria money in Cambodia.
Topics: Antimalarials; Artemisinins; Cambodia; Drug Resistance; Healthcare Financing; Humans; Malaria | 2015 |
[Youyou Tu, from Mao Zedong to the Nobel Prize].
Topics: Animals; Artemisinins; China; Communism; History, 20th Century; History, 21st Century; Humans; Malaria; Mice; Nobel Prize | 2016 |
Synergistic anti-malarial action of cryptolepine and artemisinins.
Topics: Animals; Antimalarials; Artemisinins; Cryptolepis; Drug Synergism; Drug Therapy, Combination; Indole Alkaloids; Malaria; Male; Mice; Mice, Inbred ICR; Plasmodium berghei; Quinolines; Rats; Rats, Sprague-Dawley | 2016 |
UK malaria treatment guidelines 2016.
Topics: Adult; Antimalarials; Artemisinins; Artesunate; Breast Feeding; Child; Child, Preschool; Female; Humans; Malaria; Malaria, Falciparum; Malaria, Vivax; Plasmodium falciparum; Plasmodium vivax; Pregnancy; Pregnancy Complications, Parasitic; Primaquine; Travel | 2016 |
Patterns of treatment-seeking behaviors among caregivers of febrile young children: a Ugandan multiple case study.
Topics: Adult; Antimalarials; Artemisinins; Caregivers; Child, Preschool; Combined Modality Therapy; Disease Management; Female; Fever; Health Behavior; Humans; Infant; Malaria; Male; Middle Aged; Parents; Patient Acceptance of Health Care; Population Density; Qualitative Research; Uganda; Young Adult | 2016 |
Antimalarial and cytotoxic properties of Chukrasia tabularis A. Juss and Turraea vogelii Hook F. Ex. Benth.
Topics: Animals; Antimalarials; Artemia; Artemisinins; Cell Survival; Chloroquine; Drug Resistance; Malaria; Male; Meliaceae; Mice; Plant Bark; Plant Extracts; Plant Stems; Plasmodium berghei; Plasmodium falciparum | 2016 |
Synthetic biology's first malaria drug meets market resistance.
Topics: Antimalarials; Artemisia annua; Artemisinins; Crops, Agricultural; Drug Costs; Humans; Malaria; Synthetic Biology | 2016 |
Malaria Policy Advisory Committee to the WHO: conclusions and recommendations of eighth biannual meeting (September 2015).
Topics: Antimalarials; Artemisinins; Drug Resistance; Global Health; Health Policy; Humans; Malaria; Public Health Surveillance; World Health Organization | 2016 |
Repetitive live sporozoites inoculation under arteether chemoprophylaxis confers protection against subsequent sporozoite challenge in rodent malaria model.
Topics: Animals; Antimalarials; Artemisinins; Chemoprevention; Chloroquine; Female; Immunization; Malaria; Mefloquine; Mice; Parasite Load; Plasmodium yoelii; Primaquine; Sporozoites; Vaccination | 2016 |
Back on TRAC: New trial launched in bid to outpace multidrug-resistant malaria.
Topics: Antimalarials; Artemisinins; Asia, Southeastern; Drug Resistance, Multiple; Drug Therapy, Combination; Humans; India; Malaria; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Quinolines | 2016 |
IR and Vibrational Circular Dichroism Spectroscopy of Matrine- and Artemisinin-Type Herbal Products: Stereochemical Characterization and Solvent Effects.
Topics: Alkaloids; Artemisinins; Circular Dichroism; Drugs, Chinese Herbal; Hydrogen Bonding; Malaria; Matrines; Molecular Structure; Quinolizines; Sophora | 2016 |
Assessing the effects of malaria interventions on the geographical distribution of parasitaemia risk in Burkina Faso.
Topics: Animals; Antimalarials; Artemisinins; Bayes Theorem; Burkina Faso; Child, Preschool; Climate; Culicidae; Drug Combinations; Female; Humans; Infant; Insecticide-Treated Bednets; Insecticides; Malaria; Parasitemia; Prevalence; Risk Assessment | 2016 |
Tu Youyou's Nobel Prize and the academic evaluation system in China.
Topics: Academies and Institutes; Anti-Infective Agents; Artemisinins; Biomedical Research; China; Educational Measurement; Humans; Malaria; Nobel Prize; Publishing; Research; Translational Research, Biomedical | 2016 |
Globally prevalent PfMDR1 mutations modulate Plasmodium falciparum susceptibility to artemisinin-based combination therapies.
Topics: Antimalarials; Artemisinins; Drug Resistance, Microbial; Drug Therapy, Combination; Geography; Haplotypes; Malaria; Multidrug Resistance-Associated Proteins; Mutation; Plasmodium falciparum | 2016 |
Oral artemisinin monotherapy removal from the private sector in Eastern Myanmar between 2012 and 2014.
Topics: Administration, Oral; Antimalarials; Artemisinins; Cross-Sectional Studies; Drug Therapy; Drug Utilization; Health Services Research; Humans; Malaria; Myanmar; Private Sector | 2016 |
Challenges encountered by local health volunteers in early diagnosis and prompt treatment of malaria in Myanmar artemisinin resistance containment zones.
Topics: Antimalarials; Artemisinins; Attitude of Health Personnel; Community Health Workers; Cross-Sectional Studies; Drug Resistance; Drug Therapy, Combination; Early Diagnosis; Education, Medical; Health Knowledge, Attitudes, Practice; Healthy Volunteers; Humans; Malaria; Myanmar; Secondary Prevention | 2016 |
Adherence to malaria diagnosis and treatment guidelines among healthcare workers in Ogun State, Nigeria.
Topics: Adult; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Case Management; Cross-Sectional Studies; Delivery of Health Care; Diagnostic Tests, Routine; Drug Prescriptions; Drug Therapy, Combination; Female; Guideline Adherence; Health Facilities; Health Personnel; Humans; Malaria; Male; Middle Aged; Nigeria; Practice Guidelines as Topic; Private Sector; Public Sector; Young Adult | 2016 |
Busting the billion-dollar myth: how to slash the cost of drug development.
Topics: Africa; Amodiaquine; Anti-Bacterial Agents; Artemisinins; Benzamides; Boron Compounds; Child; Clinical Trials as Topic; Cooperative Behavior; Developed Countries; Developing Countries; Drug Approval; Drug Combinations; Drug Costs; Drug Discovery; Drug Industry; Drug Repositioning; Drug Resistance, Microbial; Female; Humans; Malaria; Neglected Diseases; Negotiating; Nitroimidazoles; Organizations, Nonprofit; Sample Size; Trypanosomiasis, African; World Health Organization | 2016 |
Caregivers' treatment-seeking behaviors and predictors of whether a child received an appropriate antimalarial treatment: a household survey in rural Uganda.
Topics: Adult; Antimalarials; Artemisinins; Caregivers; Child Health Services; Child, Preschool; Combined Modality Therapy; Family Characteristics; Female; Humans; Infant; Infant, Newborn; Interviews as Topic; Malaria; Male; Patient Acceptance of Health Care; Rural Health; Rural Population; Surveys and Questionnaires; Uganda | 2016 |
Changes in the availability and affordability of subsidised artemisinin combination therapy in the private drug retail sector in rural Ghana: before and after the introduction of the AMFm subsidy.
Topics: Antimalarials; Artemisinins; Commerce; Drug Therapy, Combination; Ghana; Health Facilities; Health Services Accessibility; Humans; Malaria; Pharmacies; Private Sector; Rural Population | 2016 |
Quality of Artemisinin-based Combination Therapy for malaria found in Ghanaian markets and public health implications of their use.
Topics: Anti-Infective Agents; Antimalarials; Artemisinins; Cross-Sectional Studies; Drug Therapy, Combination; Ghana; Health Care Sector; Humans; Malaria; Public Health | 2016 |
In vitro and in vivo anti-malarial activity of novel harmine-analog heat shock protein 90 inhibitors: a possible partner for artemisinin.
Topics: Animals; Antimalarials; Artemisinins; Cell Line; Cell Survival; Disease Models, Animal; Drug Synergism; Female; Harmine; HSP90 Heat-Shock Proteins; Humans; Inhibitory Concentration 50; Malaria; Mice, Inbred BALB C; Plasmodium berghei; Plasmodium falciparum; Protein Binding; Protozoan Proteins; Treatment Outcome | 2016 |
Feasibility of Malaria Diagnosis and Management in Burkina Faso, Nigeria, and Uganda: A Community-Based Observational Study.
Topics: Administration, Oral; Antimalarials; Artemisinins; Artesunate; Burkina Faso; Child; Child, Preschool; Community Health Workers; Diagnostic Tests, Routine; Female; Humans; Infant; Malaria; Malaria, Falciparum; Male; Nigeria; Proteins; Referral and Consultation; Uganda | 2016 |
Impact of Improving Community-Based Access to Malaria Diagnosis and Treatment on Household Costs.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Burkina Faso; Child, Preschool; Community Health Workers; Family Characteristics; Female; Health Services Accessibility; Humans; Malaria; Male; Middle Aged; Nigeria; Surveys and Questionnaires; Uganda; Young Adult | 2016 |
Assessing Acceptability of a Diagnostic and Malaria Treatment Package Delivered by Community Health Workers in Malaria-Endemic Settings of Burkina Faso, Nigeria, and Uganda.
Topics: Antimalarials; Artemisinins; Artesunate; Burkina Faso; Community Health Workers; Diagnostic Tests, Routine; Female; Humans; Malaria; Male; Nigeria; Uganda | 2016 |
Using Respondent Driven Sampling to Identify Malaria Risks and Occupational Networks among Migrant Workers in Ranong, Thailand.
Topics: Adult; Aged; Antimalarials; Artemisinins; Drug Resistance; Female; Health Behavior; Health Knowledge, Attitudes, Practice; Humans; Malaria; Male; Middle Aged; Occupational Exposure; Risk Assessment; Surveys and Questionnaires; Thailand; Transients and Migrants; Young Adult | 2016 |
[Practices of caregivers and national recommendations for treatment of malaria in Benin in 2009].
Topics: Antimalarials; Artemisinins; Attitude of Health Personnel; Benin; Caregivers; Chloroquine; Cross-Sectional Studies; Drug Therapy, Combination; Female; Guideline Adherence; Health Knowledge, Attitudes, Practice; Humans; Malaria; Male; Practice Guidelines as Topic; Practice Patterns, Physicians'; Surveys and Questionnaires | 2017 |
Molecular Evidence of Drug Resistance in Asymptomatic Malaria Infections, Myanmar, 2015.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Drug Resistance; Female; Humans; Malaria; Male; Middle Aged; Mutation; Myanmar; Plasmodium; Young Adult | 2017 |
Antimalarial activity of Garcinia mangostana L rind and its synergistic effect with artemisinin in vitro.
Topics: Antimalarials; Artemisinins; Drug Synergism; Fruit; Garcinia mangostana; In Vitro Techniques; Inhibitory Concentration 50; Malaria; Plant Extracts; Plasmodium falciparum; Xanthones | 2017 |
Access to artemisinin combination therapy for malaria in remote areas of Cambodia.
Topics: Adult; Antimalarials; Artemisinins; Blood; Cambodia; Child, Preschool; Cross-Sectional Studies; Drug Therapy, Combination; Female; Health Services Accessibility; Humans; Infant; Infant, Newborn; Malaria; Male; Surveys and Questionnaires | 2008 |
Monitoring antimalarial safety and tolerability in clinical trials: a case study from Uganda.
Topics: Adverse Drug Reaction Reporting Systems; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Therapy, Combination; Humans; Infant; Malaria; Randomized Controlled Trials as Topic; Treatment Outcome; Uganda | 2008 |
The use of artemisinin-based combination therapies (ACTs) in public secondary health facilities in Lagos, Nigeria.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Antimalarials; Artemisia; Artemisinins; Child; Child, Preschool; Drug Prescriptions; Drug Therapy, Combination; Female; Hospitals, General; Humans; Incidence; Infant; Malaria; Male; Middle Aged; Nigeria; Outpatients; Practice Patterns, Physicians'; Retrospective Studies | 2008 |
Intermittent preventive antimalarial treatment to children (IPTc): firebreak or fire trap?
Topics: Amodiaquine; Antimalarials; Artemisinins; Child, Preschool; Decision Making; Drug Administration Schedule; Drug Combinations; Drug Resistance; Humans; Infant; Malaria; Pyrimethamine; Sulfadoxine | 2008 |
Overuse of artemisinin-combination therapy in Mto wa Mbu (river of mosquitoes), an area misinterpreted as high endemic for malaria.
Topics: Adolescent; Adult; Age Distribution; Animals; Anopheles; Antibodies, Protozoan; Artemisinins; Child; Child, Preschool; Drug Therapy, Combination; Endemic Diseases; Ethanolamines; Female; Fluorenes; Humans; Infant; Lumefantrine; Malaria; Male; Middle Aged; Parasitemia; Rain; Rural Health Services; Seroepidemiologic Studies; Tanzania; Young Adult | 2008 |
Amino- and hydroxy-functionalized 11-azaartemisinins and their derivatives.
Topics: Administration, Oral; Animals; Antiprotozoal Agents; Artemisinins; Aza Compounds; Drug Resistance, Multiple; Malaria; Mice; Plasmodium yoelii | 2008 |
Malaria-infected mice are cured by a single oral dose of new dimeric trioxane sulfones which are also selectively and powerfully cytotoxic to cancer cells.
Topics: Administration, Oral; Animals; Antimalarials; Antineoplastic Agents; Artemisinins; Cell Line, Tumor; Drug Screening Assays, Antitumor; Drug Stability; Drug Therapy, Combination; Humans; Malaria; Mefloquine; Mice; Sulfones | 2009 |
[Therapeutic efficacy of naphthoquine phosphate combined with artemisinine against Plasmodium knowlesi].
Topics: Animals; Antimalarials; Artemisinins; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Macaca mulatta; Malaria; Male; Naphthoquinones; Plasmodium knowlesi | 2008 |
Advances in global biotechnology and local resources to treat malaria.
Topics: Antimalarials; Artemether; Artemisia; Artemisinins; Artesunate; Drug Approval; Drug Resistance, Multiple; Drugs, Investigational; Global Health; Humans; Malaria; Minnesota; Phytotherapy | 2009 |
Evaluation of Artemisia annua infusion efficacy for the treatment of malaria in Plasmodium chabaudi chabaudi infected mice.
Topics: Animals; Anti-Infective Agents; Artemisia annua; Artemisinins; Beverages; Chromatography, Thin Layer; Densitometry; Disease Models, Animal; Female; Malaria; Mice; Parasitemia; Phytotherapy; Plant Leaves; Plasmodium chabaudi | 2009 |
New funding mechanism is launched to combat malaria.
Topics: Antimalarials; Artemisinins; Drug Combinations; Financing, Organized; Health Services Accessibility; Humans; Malaria | 2009 |
Liquid chromatographic tandem mass spectrometric assay for quantification of 97/78 and its metabolite 97/63: a promising trioxane antimalarial in monkey plasma.
Topics: Animals; Antimalarials; Artemisinins; Chromatography, Liquid; Disease Models, Animal; Humans; Macaca mulatta; Malaria; Male; Tandem Mass Spectrometry | 2009 |
Malaria drug-makers ignore WHO ban.
Topics: Antimalarials; Artemisinins; Drug Combinations; Drug Industry; Drug Resistance; Humans; Malaria; World Health Organization | 2009 |
Artemisinin-resistant Plasmodium falciparum: can the genie be put back in the bottle?
Topics: Animals; Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria; Plasmodium falciparum | 2009 |
Piloting the global subsidy: the impact of subsidized artemisinin-based combination therapies distributed through private drug shops in rural Tanzania.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Commerce; Drug Combinations; Drug Costs; Ethanolamines; Financing, Government; Fluorenes; Health Services Accessibility; Humans; Malaria; Pilot Projects; Private Sector; Pyrimethamine; Rural Health; Rural Population; Sulfadoxine; Tanzania | 2009 |
Innovating for impact: the Affordable Medicines Facility-malaria (AMFm).
Topics: Antimalarials; Artemisinins; Developing Countries; Drug Therapy, Combination; Health Services Accessibility; Humans; Malaria | 2009 |
Simple field assays to check quality of current artemisinin-based antimalarial combination formulations.
Topics: Animals; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Drug Combinations; Drug Evaluation, Preclinical; Ethanolamines; Fluorenes; Malaria; Pharmaceutical Preparations; Reference Standards; Sensitivity and Specificity; Silicon Dioxide; Tablets | 2009 |
Artemisinin-based combination therapies (ACTs) and herbal drugs crosstalk: facts and perspectives.
Topics: Animals; Anti-Infective Agents; Antimalarials; Artemisinins; Drug Therapy, Combination; Humans; Malaria; Medicine, Traditional; Plant Extracts; Plasmodium | 2009 |
Artemisinin resistance on the Thai-Cambodian border.
Topics: Antimalarials; Artemisinins; Cambodia; Drug Combinations; Drug Industry; Drug Resistance; Humans; Malaria; Thailand | 2009 |
Treatment of malaria in Austria: hazardous for patients or physicians?
Topics: Anti-Infective Agents; Artemisinins; Drug Approval; Humans; Malaria | 2009 |
Hyperparasitaemia and low dosing are an important source of anti-malarial drug resistance.
Topics: Antimalarials; Artemisinins; Dose-Response Relationship, Drug; Drug Resistance; Humans; Malaria; Parasitemia; Plasmodium; Recurrence | 2009 |
Artemisinin biosynthesis in growing plants of Artemisia annua. A 13CO2 study.
Topics: Antimalarials; Artemisia annua; Artemisinins; Biosynthetic Pathways; Carbon Dioxide; Carbon Isotopes; Malaria; Mevalonic Acid; Molecular Structure; Phytotherapy; Polycyclic Sesquiterpenes; Polyisoprenyl Phosphates; Sesquiterpenes | 2010 |
Time for a "Third Wave" of malaria activism to tackle the drug stock-out crisis.
Topics: Africa; Antimalarials; Artemisinins; Developing Countries; Drug Therapy, Combination; Healthcare Disparities; Humans; Malaria | 2009 |
Possible interruption of malaria transmission, highland Kenya, 2007-2008.
Topics: Animals; Artemether, Lumefantrine Drug Combination; Artemisinins; Drug Combinations; Ethanolamines; Fluorenes; Health Policy; Humans; Insecticides; Kenya; Malaria; Mosquito Control; Parasitemia; Polymerase Chain Reaction; Rain; Temperature; Time Factors | 2009 |
HIV protease inhibitors, indinavir or nelfinavir, augment antimalarial action of artemisinin in vitro.
Topics: Antimalarials; Artemisinins; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Malaria; Nelfinavir | 2010 |
Plant science. The botanical solution for malaria.
Topics: Animals; Antimalarials; Artemisia annua; Artemisinins; Chromosome Mapping; Crosses, Genetic; Gene Expression Profiling; Humans; Malaria; Quantitative Trait Loci; Sequence Analysis, DNA | 2010 |
The genetic map of Artemisia annua L. identifies loci affecting yield of the antimalarial drug artemisinin.
Topics: Antimalarials; Artemisia; Artemisinins; Chromosome Mapping; Crosses, Genetic; DNA, Complementary; Gene Expression Profiling; Genes, Plant; Genetic Association Studies; Humans; Malaria; Mutation; Phenotype; Polymorphism, Single Nucleotide; Quantitative Trait Loci; Sequence Analysis, DNA | 2010 |
Dual labeling with a far red probe permits analysis of growth and oxidative stress in P. falciparum-infected erythrocytes.
Topics: Animals; Artemisinins; Catalase; Chloroquine; Cysteine Proteases; Erythrocytes; Flow Cytometry; Fluorescent Dyes; Humans; Malaria; Models, Biological; Nucleic Acids; Oxidative Stress; Oxygen; Plasmodium falciparum | 2010 |
Artemisinin directly targets malarial mitochondria through its specific mitochondrial activation.
Topics: Anti-Infective Agents; Antimalarials; Artemisinins; Malaria; Mitochondria; Mitochondrial Membranes; Models, Chemical; Oxygen Consumption; Peroxides; Plasmodium berghei; Plasmodium falciparum; Reactive Oxygen Species | 2010 |
Malaria treatment by using artemisinin in Indonesia.
Topics: Anti-Infective Agents; Antimalarials; Artemisinins; Drug Resistance; Drug Therapy, Combination; Humans; Indonesia; Malaria; Treatment Failure | 2010 |
Ancient Chinese methods are remarkably effective for the preparation of artemisinin-rich extracts of Qing Hao with potent antimalarial activity.
Topics: Administration, Oral; Animals; Antimalarials; Artemisinins; Drugs, Chinese Herbal; Malaria; Medicine, Chinese Traditional; Mice; Plasmodium berghei | 2010 |
Advances in the treatment of malaria.
Topics: Antimalarials; Artemisinins; Drug Therapy, Combination; Humans; Malaria | 2010 |
In vitro antiplasmodial and phytochemical study of five Artemisia species from Iran and in vivo activity of two species.
Topics: Animals; Antimalarials; Artemisia; Artemisia absinthium; Artemisia annua; Artemisinins; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Drug Resistance, Multiple; Female; Iran; Magnetic Resonance Spectroscopy; Malaria; Mice; Mice, Inbred BALB C; Parasitic Sensitivity Tests; Plant Extracts; Plasmodium berghei; Plasmodium falciparum; Species Specificity | 2010 |
Dynamics of Plasmodium falciparum parasitemia regarding combined treatment regimens for acute uncomplicated malaria, Antioquia, Colombia.
Topics: Administration, Oral; Animals; Antimalarials; Artemisinins; Artesunate; Clinical Protocols; Colombia; Drug Therapy, Combination; Female; Humans; Malaria; Malaria, Falciparum; Male; Mefloquine; Parasitemia; Patient Compliance; Plasmodium falciparum; Primaquine; Treatment Outcome | 2010 |
Soft targets or partners in health? Retail pharmacies and their role in Tanzania's malaria control program.
Topics: Adult; Antimalarials; Artemisinins; Attitude of Health Personnel; Drug Therapy, Combination; Female; Health Policy; Humans; Interviews as Topic; Malaria; Observation; Pharmacies; Pharmacists; Practice Guidelines as Topic; Professional Role; Professional-Patient Relations; Social Responsibility; Tanzania; Young Adult | 2010 |
Demand for malaria drug soars.
Topics: Agriculture; Artemisia annua; Artemisinins; Chloroquine; Drug Costs; Drug Resistance; Humans; Malaria | 2010 |
Experimental evolution, genetic analysis and genome re-sequencing reveal the mutation conferring artemisinin resistance in an isogenic lineage of malaria parasites.
Topics: Animals; Artemisinins; Computer Simulation; Directed Molecular Evolution; DNA Copy Number Variations; Drug Resistance; Genes, Protozoan; Genome, Protozoan; Genotype; Humans; INDEL Mutation; Malaria; Mutagenesis, Insertional; Mutation; Parasites; Phenotype; Phylogeny; Plasmodium chabaudi; Point Mutation; Pyrimethamine; Sequence Analysis, DNA; Sequence Deletion | 2010 |
Who gets prompt access to artemisinin-based combination therapy? A prospective community-based study in children from rural Kilosa, Tanzania.
Topics: Artemisinins; Child, Preschool; Data Collection; Drug Therapy, Combination; Female; Government; Health Facilities; Health Services Accessibility; Humans; Infant; Malaria; Male; Prospective Studies; Rural Population; Tanzania; Time Factors | 2010 |
Plasmodium berghei K173: selection of resistance to naphthoquine in a mouse model.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Dose-Response Relationship, Drug; Drug Resistance; Ethanolamines; Fluorenes; Lumefantrine; Malaria; Male; Mice; Naphthoquinones; Plasmodium berghei; Pyrimethamine; Random Allocation | 2011 |
UK treatment of malaria.
Topics: Anti-Infective Agents; Antimalarials; Artemisinins; Child; Humans; Malaria; Malaria, Falciparum; Treatment Outcome; United Kingdom | 2011 |
A single, low, oral dose of a 5-carbon-linked trioxane dimer orthoester plus mefloquine cures malaria-infected mice.
Topics: Administration, Oral; Animals; Antimalarials; Artemisinins; Crystallography, X-Ray; Drug Therapy, Combination; Esters; Heterocyclic Compounds; Heterocyclic Compounds, 4 or More Rings; Malaria; Mefloquine; Mice; Molecular Structure; Plasmodium berghei | 2011 |
Implication of intracellular glutathione and its related enzymes on resistance of malaria parasites to the antimalarial drug arteether.
Topics: Animals; Antimalarials; Artemisinins; Drug Resistance; Glucosephosphate Dehydrogenase; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Malaria; Mice; Parasitic Sensitivity Tests; Plasmodium | 2011 |
In areas of low transmission, is the presumptive treatment of febrile but bloodsmear-negative patients for malaria validated by the results of PCR-based testing?
Topics: Antigens, Protozoan; Antimalarials; Artemisinins; Female; Fever; Humans; Malaria; Malaria, Falciparum; Male; Plasmodium falciparum; Polymerase Chain Reaction; Sudan | 2010 |
Malaria prevention and control in Bhutan: successes and challenges.
Topics: Animals; Anopheles; Artemisinins; Bhutan; Drug Therapy, Combination; Humans; Insecticides; Malaria; Morbidity; Mortality; Mosquito Control; Mosquito Nets; Plasmodium falciparum; Plasmodium vivax; Population | 2011 |
Design, synthesis, and study of a mycobactin-artemisinin conjugate that has selective and potent activity against tuberculosis and malaria.
Topics: Antitubercular Agents; Artemisinins; Drug Design; Iron Chelating Agents; Malaria; Molecular Structure; Mycobacterium tuberculosis; Oxazoles; Tuberculosis | 2011 |
Improving rational treatment of malaria: perceptions and influence of RDTs on prescribing behaviour of health workers in southeast Nigeria.
Topics: Antimalarials; Artemisinins; Community Health Workers; Diagnostic Tests, Routine; Humans; Malaria; Nigeria; Practice Patterns, Physicians'; Reagent Kits, Diagnostic | 2011 |
Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malaria.
Topics: Adamantane; Animals; Antimalarials; Artemisinins; Dose-Response Relationship, Drug; Drug Stability; Heterocyclic Compounds; Iron; Malaria; Male; Mice; Peroxides; Plasmodium berghei; Rats; Rats, Sprague-Dawley; Time Factors; Treatment Outcome | 2011 |
Feasibility of malaria elimination.
Topics: Anti-Infective Agents; Antimalarials; Artemisinins; Drug Therapy, Combination; Humans; Insecticides; International Cooperation; Malaria; Mosquito Control; Mosquito Nets | 2011 |
Measuring the AMFm.
Topics: Antimalarials; Artemisinins; Burkina Faso; Drug Costs; Humans; Malaria | 2011 |
Assessment of global reporting of adverse drug reactions for anti-malarials, including artemisinin-based combination therapy, to the WHO Programme for International Drug Monitoring.
Topics: Adverse Drug Reaction Reporting Systems; Antimalarials; Artemisinins; Drug Therapy, Combination; Global Health; Humans; Malaria; World Health Organization | 2011 |
Millet-porridge with Artemisia annua as first aid for African children with malaria?
Topics: Antimalarials; Artemisia annua; Artemisinins; Child; Chromatography, High Pressure Liquid; Edible Grain; Food, Fortified; Humans; Malaria; Panicum; Phytotherapy; Plant Leaves; Plant Preparations; Taste | 2011 |
Antimalarial activity of endoperoxide compound 6-(1,2,6,7-tetraoxaspiro[7.11]nonadec-4-yl)hexan-1-ol.
Topics: Administration, Oral; Animals; Antimalarials; Artemisinins; Cell Line, Tumor; Drug Therapy, Combination; Erythrocytes; Heterocyclic Compounds, 2-Ring; Hexanols; Humans; Malaria; Malaria, Falciparum; Mice; Mice, Inbred ICR; Molecular Structure; Parasitemia; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Rats; Spiro Compounds; Survival Analysis; Tetraoxanes | 2011 |
Grand rounds: The opportunity for and challenges to malaria eradication.
Topics: Adult; Africa; Antimalarials; Artemisinins; Child; Cost of Illness; Female; Global Health; Humans; Insecticide-Treated Bednets; Insecticides; Malaria; Malaria Vaccines; Pregnancy | 2011 |
Development, evaluation, and application of an in silico model for antimalarial drug treatment and failure.
Topics: Antimalarials; Artemisinins; Humans; Malaria; Models, Theoretical | 2011 |
WHO urges the phasing out of artemisinin based monotherapy for malaria to reduce resistance.
Topics: Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria; World Health Organization | 2011 |
The Plasmodium falciparum Ca(2+)-ATPase PfATP6: insensitive to artemisinin, but a potential drug target.
Topics: Animals; Anti-Infective Agents; Artemisinins; Binding Sites; Calcium-Transporting ATPases; Drug Design; Humans; Isoenzymes; Malaria; Models, Molecular; Plasmodium falciparum; Protein Conformation; Rabbits | 2011 |
Treatment of uncomplicated malaria at public health facilities and medicine retailers in south-eastern Nigeria.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Child, Preschool; Cross-Sectional Studies; Drug Therapy, Combination; Drug Utilization; Female; Guideline Adherence; Humans; Infant; Malaria; Male; Nigeria; Pregnancy; Young Adult | 2011 |
Genomewide scan reveals amplification of mdr1 as a common denominator of resistance to mefloquine, lumefantrine, and artemisinin in Plasmodium chabaudi malaria parasites.
Topics: Antimalarials; Artemisinins; Base Sequence; Chromosome Mapping; Drug Resistance, Multiple; Ethanolamines; Fluorenes; Genetic Linkage; Genome, Protozoan; Lumefantrine; Malaria; Mefloquine; Multidrug Resistance-Associated Proteins; Plasmodium chabaudi; Sequence Analysis, DNA | 2011 |
Design and evaluation of primaquine-artemisinin hybrids as a multistage antimalarial strategy.
Topics: Animals; Antimalarials; Artemisinins; Cell Line; Humans; Malaria; Mice; Parasitemia; Plasmodium berghei; Plasmodium falciparum; Primaquine | 2011 |
Current status of the clinical development and implementation of paediatric artemisinin combination therapies in Sub-Saharan Africa.
Topics: Africa South of the Sahara; Anti-Infective Agents; Antimalarials; Artemisinins; Child; Drug Compounding; Drug Therapy, Combination; Female; Humans; Malaria; Male | 2011 |
Malaria morbidity and pyrethroid resistance after the introduction of insecticide-treated bednets and artemisinin-based combination therapies: a longitudinal study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antimalarials; Artemisinins; Child; Child, Preschool; Culicidae; Drug Resistance; Female; Humans; Incidence; Infant; Infant, Newborn; Insect Bites and Stings; Insecticide-Treated Bednets; Longitudinal Studies; Malaria; Middle Aged; Morbidity; Mosquito Control; Plasmodium; Prevalence; Pyrethrins; Young Adult | 2011 |
From bark to weed: the history of artemisinin.
Topics: Antimalarials; Artemisinins; China; History, 20th Century; History, Ancient; Humans; Malaria | 2011 |
Knowledge and malaria treatment practices using artemisinin combination therapy (ACT) in Malawi: survey of health professionals.
Topics: Adult; Antimalarials; Artemisinins; Attitude of Health Personnel; Cross-Sectional Studies; Drug Therapy, Combination; Female; Guideline Adherence; Humans; Malaria; Malawi; Male; Pharmacists; Physicians; Professional Competence; Surveys and Questionnaires | 2011 |
Five years of antimalarial resistance marker surveillance in Gaza Province, Mozambique, following artemisinin-based combination therapy roll out.
Topics: Adolescent; Alleles; Animals; Antimalarials; Artemisinins; Child; Drug Resistance; Drug Therapy, Combination; Geography; Humans; Malaria; Mozambique; Mutation; Parasites; Population Surveillance | 2011 |
Artemisinin: the gifts from traditional Chinese medicine not only for malaria control but also for schistosomiasis control.
Topics: Animals; Anthelmintics; Artemisinins; China; Humans; Lepidoptera; Malaria; Medicine, Chinese Traditional; Schistosomiasis | 2012 |
From branch to bedside: Youyou Tu is awarded the 2011 Lasker~DeBakey Clinical Medical Research Award for discovering artemisinin as a treatment for malaria.
Topics: Animals; Artemisinins; Awards and Prizes; China; History, 20th Century; History, 21st Century; Humans; Malaria; Medicine, Chinese Traditional; Models, Biological; Translational Research, Biomedical | 2011 |
Malaria prevalence and treatment of febrile patients at health facilities and medicine retailers in Cameroon.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Cameroon; Child; Child, Preschool; Commerce; Cross-Sectional Studies; Female; Fever; Health Facilities; Humans; Infant; Malaria; Male; Odds Ratio; Patient Acceptance of Health Care; Pharmacies; Physical Examination; Plant Extracts; Prescriptions; Prevalence; Private Sector; Public Sector; Young Adult | 2012 |
Artemisinin and artemisinin plus curcumin liposomal formulations: enhanced antimalarial efficacy against Plasmodium berghei-infected mice.
Topics: Animals; Antimalarials; Artemisinins; Chemistry, Pharmaceutical; Curcumin; Drug Carriers; Drug Stability; Drug Therapy, Combination; Female; Liposomes; Malaria; Mice; Mice, Inbred BALB C; Nanoparticles; Particle Size; Plasmodium berghei; Polyethylene Glycols | 2012 |
Generation of the potent anti-malarial drug artemisinin in tobacco.
Topics: Antimalarials; Artemisia annua; Artemisinins; Genetic Vectors; Humans; Malaria; Metabolic Networks and Pathways; Molecular Structure; NADPH-Ferrihemoprotein Reductase; Nicotiana; Oxidoreductases; Plant Proteins; Plants, Genetically Modified; Polycyclic Sesquiterpenes; Sesquiterpenes | 2011 |
Rapid assessment of the performance of malaria control strategies implemented by countries in the Amazon subregion using adequacy criteria: case study.
Topics: Antimalarials; Artemisinins; Bolivia; Colombia; Data Collection; Disease Eradication; Disease Transmission, Infectious; Drug Combinations; Ecuador; Guyana; Humans; Insecticide-Treated Bednets; Insecticides; Malaria; Mosquito Control; Peru; Plasmodium; Program Evaluation | 2011 |
Optimal dose finding for novel antimalarial combination therapy.
Topics: Antimalarials; Artemisinins; Biomedical Research; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Design; Drug Dosage Calculations; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Models, Statistical; Plasmodium; Quinine | 2012 |
[Use of intravenous artemisinin derivatives in severe malaria].
Topics: Antimalarials; Artemisinins; Artesunate; Child, Preschool; Female; Humans; Injections, Intravenous; Malaria; Male; Severity of Illness Index | 2012 |
Artemisinin combination therapies price disparity between government and private health sectors and its implication on antimalarial drug consumption pattern in Morogoro Urban District, Tanzania.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Cities; Demography; Drug Therapy, Combination; Female; Government; Health Care Sector; Health Knowledge, Attitudes, Practice; Healthcare Disparities; Humans; Malaria; Male; Middle Aged; Private Sector; Tanzania; Young Adult | 2012 |
Designing adverse event forms for real-world reporting: participatory research in Uganda.
Topics: Adverse Drug Reaction Reporting Systems; Anti-Infective Agents; Artemisinins; Community-Based Participatory Research; Drug Monitoring; Drug Therapy, Combination; Humans; Malaria; Pharmacovigilance; Reproducibility of Results; Research Design; Uganda | 2012 |
Malaria.
Topics: Africa; Artemisinins; Asia, Southeastern; Endemic Diseases; Health Services Accessibility; Humans; Malaria | 2012 |
Drug development: Holding out for reinforcements.
Topics: Antimalarials; Artemisinins; Asia, Southeastern; Drug Discovery; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Plasmodium; Time Factors | 2012 |
Public health: Death at the doorstep.
Topics: Animals; Antimalarials; Artemisinins; Child, Preschool; Culicidae; Drug Therapy, Combination; Female; Health Education; Health Services Accessibility; Humans; Infant; International Cooperation; Malaria; Male; Plasmodium; Public Health; Uganda; World Health Organization | 2012 |
Perspectives: The missing pieces.
Topics: Animals; Anopheles; Antigens, Protozoan; Antimalarials; Artemisinins; Biomedical Research; Drug Resistance; Erythrocytes; Female; Hepatocytes; Humans; Malaria; Malaria Vaccines; Mosquito Control; Plasmodium; Primaquine; Sporozoites; Vaccines, Attenuated | 2012 |
Malaria subsidy pilot soars, but some see turbulence ahead.
Topics: Antimalarials; Artemisinins; Drug Costs; Drug Therapy, Combination; Humans; Malaria | 2012 |
Willingness-to-pay for a rapid malaria diagnostic test and artemisinin-based combination therapy from private drug shops in Mukono District, Uganda.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Drug Costs; Drug Therapy, Combination; Female; Financing, Personal; Humans; Malaria; Male; Middle Aged; Patient Acceptance of Health Care; Pharmacies; Reagent Kits, Diagnostic; Uganda; Young Adult | 2013 |
Flow chemistry: a light touch to a deadly problem.
Topics: Antimalarials; Artemisinins; Chromatography, High Pressure Liquid; Drug Discovery; Humans; Malaria | 2012 |
Harmine is a potent antimalarial targeting Hsp90 and synergizes with chloroquine and artemisinin.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Synergism; Harmaline; Harmine; HSP90 Heat-Shock Proteins; Malaria; Mice; Mice, Inbred BALB C; Mutagenesis, Site-Directed; Plasmodium berghei; Plasmodium falciparum; Protein Structure, Quaternary; Protein Structure, Tertiary; Surface Plasmon Resonance | 2012 |
Factors associated with non-adherence to Artemisinin-based combination therapy (ACT) to malaria in a rural population from holoendemic region of western Kenya.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Child; Child, Preschool; Cross-Sectional Studies; Drug Therapy, Combination; Female; Humans; Infant; Infant, Newborn; Kenya; Malaria; Male; Medication Adherence; Middle Aged; Rural Population; Surveys and Questionnaires; Young Adult | 2012 |
Community health workers use malaria rapid diagnostic tests (RDTs) safely and accurately: results of a longitudinal study in Zambia.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Clinical Competence; Female; Health Personnel; Humans; Longitudinal Studies; Malaria; Male; Middle Aged; Young Adult; Zambia | 2012 |
Complementary and alternative medicine: is it possible to be mainstream?
Topics: Artemisinins; Complementary Therapies; Delivery of Health Care; Humans; Malaria; Practice Patterns, Physicians'; Treatment Outcome | 2012 |
A concise synthesis of (+)-artemisinin.
Topics: Antimalarials; Artemisia annua; Artemisinins; Humans; Malaria; Stereoisomerism | 2012 |
Malaria-infected mice live until at least day 30 after a new artemisinin-derived thioacetal thiocarbonate combined with mefloquine are administered together in a single, low, oral dose.
Topics: Acetals; Administration, Oral; Animals; Antimalarials; Artemisinins; Magnetic Resonance Spectroscopy; Malaria; Mefloquine; Mice; Mice, Inbred C57BL; Spectrometry, Mass, Fast Atom Bombardment | 2012 |
Adoption of rapid diagnostic tests for the diagnosis of malaria, a preliminary analysis of the Global Fund program data, 2005 to 2010.
Topics: Antimalarials; Artemisinins; Diagnostic Tests, Routine; Health Care Costs; Health Services Accessibility; Humans; International Cooperation; Malaria; Program Evaluation; Reagent Kits, Diagnostic; United States; World Health Organization | 2012 |
Are patent medicine vendors effective agents in malaria control? Using lot quality assurance sampling to assess quality of practice in Jigawa, Nigeria.
Topics: Antimalarials; Artemisinins; Commerce; Drug Resistance; Guidelines as Topic; Health Services Accessibility; Humans; Malaria; Nigeria; Pharmacies; Quality Assurance, Health Care; Quality of Health Care | 2012 |
First-time comparison of the in vitro antimalarial activity of Artemisia annua herbal tea and artemisinin.
Topics: Antimalarials; Artemisia; Artemisinins; Beverages; Cost-Benefit Analysis; Drug Resistance, Microbial; Female; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Malaria; Male; Plant Extracts; Plasmodium falciparum; Reproducibility of Results; Saponins; Solubility | 2012 |
Scale-up of home-based management of malaria based on rapid diagnostic tests and artemisinin-based combination therapy in a resource-poor country: results in Senegal.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Child; Child, Preschool; Community Health Workers; Diagnostic Tests, Routine; Drug Therapy, Combination; Female; Health Services Administration; Health Services Research; Humans; Infant; Infant, Newborn; Malaria; Male; Middle Aged; Pregnancy; Senegal; Young Adult | 2012 |
Antimalarial and anticancer activities of artemisinin-quinoline hybrid-dimers and pharmacokinetic properties in mice.
Topics: Animals; Antimalarials; Antineoplastic Agents; Artemisinins; Cell Line, Tumor; Humans; Malaria; Male; Mice; Mice, Inbred C57BL; Parasitemia; Plasmodium falciparum; Quinolines | 2012 |
Project to increase availability of malaria drug has worked, study finds.
Topics: Africa; Antimalarials; Artemisinins; Drug Costs; Health Services Accessibility; Humans; Malaria; Marketing of Health Services | 2012 |
Access to artemisinin-combination therapy (ACT) and other anti-malarials: national policy and markets in Sierra Leone.
Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Drug Costs; Geography; Health Policy; Health Services Accessibility; Humans; Malaria; Organizations, Nonprofit; Pharmacies; Poverty; Private Sector; Public Sector; Sierra Leone | 2012 |
Counter perspective: artemisinin resistance: facts, fears, and fables.
Topics: Antimalarials; Artemisinins; Humans; Malaria | 2012 |
Too much to ask.
Topics: Africa; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Drug Therapy, Combination; Humans; Malaria | 2012 |
Stabilizing supply of artemisinin and artemisinin-based combination therapy in an era of wide-spread scale-up.
Topics: Antimalarials; Artemisinins; Drug Costs; Drug Industry; Drug Therapy, Combination; Global Health; Humans; Malaria | 2012 |
In the Global Fund's court: experimentation, evaluation, and the AMFm.
Topics: Antimalarials; Artemisinins; Drug Combinations; Financing, Organized; Global Health; Humans; Malaria | 2012 |
Transitioning from malaria control to elimination: the vital role of ACTs.
Topics: Antimalarials; Artemisinins; Chemoprevention; Disease Eradication; Humans; Malaria | 2013 |
Effect of single nucleotide polymorphisms in cytochrome P450 isoenzyme and N-acetyltransferase 2 genes on the metabolism of artemisinin-based combination therapies in malaria patients from Cambodia and Tanzania.
Topics: Alleles; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Arylamine N-Acetyltransferase; Base Sequence; Cambodia; Cytochrome P-450 Enzyme System; Drug Combinations; Ethanolamines; Fluorenes; Gene Frequency; Humans; Isoenzymes; Malaria; Mefloquine; Pharmacogenetics; Polymorphism, Single Nucleotide; Quinolines; Sequence Analysis, DNA; Tanzania | 2013 |
Dried whole plant Artemisia annua as an antimalarial therapy.
Topics: Animals; Antimalarials; Artemisia annua; Artemisinins; Humans; Malaria; Mice; Parasitemia; Plant Leaves; Plants, Medicinal; Plasmodium chabaudi | 2012 |
Understanding the impact of subsidizing artemisinin-based combination therapies (ACTs) in the retail sector--results from focus group discussions in rural Kenya.
Topics: Antimalarials; Artemisinins; Female; Focus Groups; Humans; Kenya; Malaria; Male; Medication Adherence | 2013 |
Safety monitoring of artemisinin combination therapy through a national pharmacovigilance system in an endemic malaria setting.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Endemic Diseases; Female; Humans; Infant; Malaria; Male; Middle Aged; Pharmacovigilance; Senegal; Young Adult | 2013 |
Structure-activity relationships of the antimalarial agent artemisinin. 7. Direct modification of (+)-artemisinin and in vivo antimalarial screening of new, potential preclinical antimalarial candidates.
Topics: Administration, Oral; Animals; Antimalarials; Artemisinins; Drug Evaluation, Preclinical; Drug Resistance; Injections, Intravenous; Malaria; Mice; Plasmodium berghei; Plasmodium falciparum; Plasmodium yoelii; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Stereoisomerism; Structure-Activity Relationship | 2002 |
New malaria drug candidate could cure in a single dose.
Topics: Animals; Antimalarials; Artemisinins; Clinical Trials, Phase I as Topic; Humans; Investigational New Drug Application; Malaria; Mice; Peroxides; Sesquiterpenes; Treatment Outcome | 2002 |
The chemotherapy of rodent malaria. LX. The importance of formulation in evaluating the blood schizontocidal activity of some endoperoxide antimalarials.
Topics: Administration, Oral; Animals; Antimalarials; Artemisinins; Bridged Bicyclo Compounds, Heterocyclic; Chemistry, Pharmaceutical; Corn Oil; Drug Carriers; Drug Evaluation, Preclinical; Injections, Subcutaneous; Lipids; Malaria; Mice; Parasitemia; Peroxides; Plasmodium berghei; Plasmodium yoelii; Sesquiterpenes; Spiro Compounds; Styrenes; Water | 2002 |
ACT now--with caution--for malaria treatments.
Topics: Africa; Antimalarials; Artemisinins; Drug Resistance, Multiple; Humans; Malaria; Sesquiterpenes | 2003 |
An affordable antimalarial.
Topics: Antimalarials; Artemisia; Artemisinins; Cost Control; Developing Countries; Drug Resistance, Microbial; Escherichia coli; Genetic Engineering; Humans; Lactones; Malaria; Sesquiterpenes | 2004 |
Drug combinations for malaria: time to ACT?
Topics: Africa; Antimalarials; Artemisinins; Asia, Southeastern; Communicable Diseases, Emerging; Drug Resistance; Drug Therapy, Combination; Humans; Incidence; Malaria; Malaria, Falciparum; Parasitemia; Sesquiterpenes | 2004 |
Global fund changes tack on malaria therapy.
Topics: Africa; Antimalarials; Artemisinins; Drug Costs; Gift Giving; Humans; International Cooperation; Malaria; Sesquiterpenes; World Health Organization | 2004 |
Medicinal chemistry: a worthy adversary for malaria.
Topics: Animals; Antimalarials; Artemisinins; Biological Availability; Drug Design; Drug Evaluation, Preclinical; Humans; Inhibitory Concentration 50; Malaria; Sesquiterpenes | 2004 |
Identification of an antimalarial synthetic trioxolane drug development candidate.
Topics: Animals; Antimalarials; Artemisinins; Biological Availability; Drug Design; Drug Evaluation, Preclinical; Half-Life; Heterocyclic Compounds, 1-Ring; Humans; Inhibitory Concentration 50; Malaria; Mice; Oxidation-Reduction; Peroxides; Plasmodium berghei; Plasmodium falciparum; Rats; Rats, Wistar; Sesquiterpenes; Solubility; Spiro Compounds; Tissue Distribution | 2004 |
The paradox of home management of malaria with artemisinin combinations.
Topics: Africa; Animals; Antimalarials; Artemisinins; Drug Therapy, Combination; Home Nursing; Humans; Malaria; Patient Education as Topic; Sesquiterpenes; World Health Organization | 2004 |
A threshold analysis of the cost-effectiveness of artemisinin-based combination therapies in sub-saharan Africa.
Topics: Africa South of the Sahara; Antimalarials; Artemisinins; Cost-Benefit Analysis; Decision Trees; Drug Therapy, Combination; Humans; Malaria; Models, Theoretical; Monte Carlo Method; Sesquiterpenes | 2004 |
Evidence that haem iron in the malaria parasite is not needed for the antimalarial effects of artemisinin.
Topics: Animals; Antimalarials; Artemisinins; Carbon Monoxide; Chloroquine; Erythrocytes; Heme; Hemoglobins; Humans; Iron; Malaria; Oxidation-Reduction; Oxidative Stress; Oxygen; Plasmodium falciparum; Sesquiterpenes | 2004 |
Combination therapy counteracts the enhanced transmission of drug-resistant malaria parasites to mosquitoes.
Topics: Alleles; Animals; Anopheles; Antimalarials; Artemisinins; ATP-Binding Cassette Transporters; Chloroquine; Drug Resistance; Drug Therapy, Combination; Genotype; Humans; Malaria; Membrane Proteins; Membrane Transport Proteins; Plasmodium falciparum; Protozoan Proteins; Sesquiterpenes | 2004 |
Synthetic antimalaria drug enters clinical trials.
Topics: Antimalarials; Artemisinins; Clinical Trials as Topic; Drug Costs; Drug Design; Drug Therapy, Combination; Heterocyclic Compounds, 1-Ring; Humans; Malaria; Peroxides; Research Support as Topic; Sesquiterpenes; Spiro Compounds; Thailand | 2004 |
Campaign to fight malaria hit by surge in demand for medicine.
Topics: Antimalarials; Artemisinins; Drug Industry; Drug Therapy, Combination; Humans; Malaria; Sesquiterpenes; World Health Organization | 2004 |
Amodiaquine during pregnancy.
Topics: Adult; Amodiaquine; Antimalarials; Artemisinins; Drug Therapy, Combination; Female; Humans; Malaria; Pregnancy; Pregnancy Complications, Parasitic; Safety; Sesquiterpenes; Treatment Outcome | 2004 |
[Construction of the subtracted cDNA libraries related to artemisinin-resistance of Plasmodium berghei].
Topics: Animals; Anti-Infective Agents; Artemisinins; DNA, Complementary; Drug Resistance; Genomic Library; Malaria; Male; Mice; Nucleic Acid Hybridization; Plasmodium berghei; Sequence Analysis, DNA; Sesquiterpenes | 2004 |
Fake antimalarials in Southeast Asia are a major impediment to malaria control: multinational cross-sectional survey on the prevalence of fake antimalarials.
Topics: Antimalarials; Artemisinins; Artesunate; Asia, Southeastern; Cross-Sectional Studies; Drug Labeling; Fraud; Humans; Malaria; Mefloquine; Self Medication; Sesquiterpenes | 2004 |
Editorial: Should artemisinin-based combination treatment be used in the home-based management of malaria?
Topics: Africa; Antimalarials; Artemisinins; Developing Countries; Drug Combinations; Humans; Malaria; Self Medication; Sesquiterpenes | 2005 |
Combination drug policy for malaria.
Topics: Anti-Infective Agents; Antimalarials; Artemisinins; Developing Countries; Drug Therapy, Combination; Financing, Organized; Humans; Malaria; Sesquiterpenes | 2005 |
[Artemisinin and successors].
Topics: Animals; Antimalarials; Artemisinins; Heterocyclic Compounds, 1-Ring; Humans; Malaria; Peroxides; Sesquiterpenes; Spiro Compounds | 2005 |
Malaria control in Vietnam: the Binh Thuan experience.
Topics: Animals; Artemisinins; Bedding and Linens; Endemic Diseases; Government Programs; Humans; Incidence; Insect Vectors; Insecticides; Malaria; Mosquito Control; Program Evaluation; Sesquiterpenes; Vietnam | 2005 |
International partnership launches malaria model in Zambia.
Topics: Africa; Animals; Artemisinins; Bedding and Linens; Child Mortality; Child, Preschool; Government Programs; Humans; Insecticides; International Cooperation; Malaria; National Health Programs; Sesquiterpenes; Zambia | 2005 |
The antimalarial drug artemisinin alkylates heme in infected mice.
Topics: Alkylation; Animals; Antimalarials; Artemisinins; Female; Heme; Malaria; Mice; Plasmodium; Sesquiterpenes; Spleen; Urine | 2005 |
Artemisinin-based combination treatment for malaria in Africa: no perfect solutions.
Topics: Africa; Antimalarials; Artemisinins; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Sesquiterpenes | 2005 |
Antimalarial treatment with artemisinin combination therapy in Africa.
Topics: Antimalarials; Artemisinins; Drug Therapy, Combination; Humans; Malaria; Sesquiterpenes | 2005 |
Arata Kochi profile. Fighting words from WHO's new malaria chief.
Topics: Antimalarials; Artemisinins; Developing Countries; Drug Industry; Drug Resistance; Drug Therapy, Combination; History, 20th Century; History, 21st Century; Humans; Japan; Malaria; Sesquiterpenes; World Health Organization | 2006 |
[Selective enzyme inhibitor instead of an "iron-triggered cluster bomb"].
Topics: Animals; Antimalarials; Artemisinins; Humans; Malaria; Plasmodium falciparum; Sesquiterpenes | 2006 |
The history of qing hao in the Chinese materia medica.
Topics: Anti-Infective Agents; Artemisia; Artemisinins; Fever; History, 16th Century; History, 20th Century; History, Medieval; Humans; Malaria; Medicine, Chinese Traditional; Phytotherapy; Plant Preparations; Sesquiterpenes | 2006 |
Safety of artemisinin antimalarials.
Topics: Antimalarials; Artemisinins; Ataxia; Humans; Malaria; Sesquiterpenes; Tremor | 2006 |
Malaria breakthrough raises spectre of drug resistance.
Topics: Antimalarials; Artemisinins; Drug Evaluation, Preclinical; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Sesquiterpenes; World Health Organization | 2006 |
Curcumin-artemisinin combination therapy for malaria.
Topics: Animals; Antimalarials; Artemisinins; Curcumin; Drug Therapy, Combination; Inhibitory Concentration 50; Malaria; Mice; Parasitemia; Plasmodium berghei; Plasmodium falciparum; Sesquiterpenes; Survival Analysis; Treatment Outcome | 2006 |
WHO ultimatum on artemisinin monotherapy is showing results.
Topics: Antimalarials; Artemisinins; Humans; Malaria; Sesquiterpenes; World Health Organization | 2006 |
Supporting the use of artemisinin in combination.
Topics: Antimalarials; Artemisinins; Drug Costs; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Sesquiterpenes | 2006 |
WHO calls for an immediate halt to provision of single-drug artemisinin malaria pills. New malaria treatment guidelines issued by WHO.
Topics: Anti-Infective Agents; Artemisinins; Drug Resistance, Bacterial; Humans; Malaria; Marketing of Health Services; Practice Guidelines as Topic; Sesquiterpenes; World Health Organization | 2006 |
A case-control auditory evaluation of patients treated with artemether-lumefantrine.
Topics: Anti-Infective Agents; Artemisinins; Audiometry; Auditory Threshold; Case-Control Studies; Ethanolamines; Fluorenes; Hearing Loss; Humans; Lumefantrine; Malaria; Research; Sesquiterpenes; Time Factors | 2006 |
Editorial: natural products chemistry in China.
Topics: Alkaloids; Alzheimer Disease; Artemisinins; Biological Products; Malaria; Medicine, Chinese Traditional; Sesquiterpenes | 2006 |
Neurotoxicity of artemisinin derivatives.
Topics: Antimalarials; Artemisinins; Humans; Malaria; Neurotoxicity Syndromes; Sesquiterpenes | 2006 |
Erythrocyte G protein as a novel target for malarial chemotherapy.
Topics: Adrenergic beta-Antagonists; Animals; Antimalarials; Antiprotozoal Agents; Artemisinins; Drug Therapy, Combination; Erythrocyte Membrane; Erythrocytes; GTP-Binding Proteins; Humans; Malaria; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Molecular Sequence Data; Nucleotidases; Plasmodium falciparum; Propranolol; Sesquiterpenes; Signal Transduction; Trophozoites | 2006 |
Antimalarial drug prescribing practice in private and public health facilities in South-east Nigeria: a descriptive study.
Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Resistance; Drug Therapy, Combination; Female; Guideline Adherence; Health Policy; Hospitals, Public; Humans; Malaria; Male; Medical Audit; Nigeria; Plasmodium falciparum; Practice Patterns, Physicians'; Private Practice; Rural Population; Sesquiterpenes; Urban Population | 2007 |
Antimalarial drugs--here and on the horizon.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Aspartic Acid Endopeptidases; Drug Combinations; Drug Industry; Drug Resistance; GTP-Binding Proteins; Humans; Interdisciplinary Communication; Malaria; Medical Missions; Plasmodium falciparum; Sesquiterpenes; Signal Transduction | 2007 |
Improving surveillance for antimalarial drug resistance.
Topics: Antimalarials; Artemisinins; Drug Resistance; Drug Therapy, Combination; Global Health; Humans; Malaria; Population Surveillance; Sesquiterpenes | 2007 |
The challenges of changing national malaria drug policy to artemisinin-based combinations in Kenya.
Topics: Antimalarials; Artemisinins; Community Health Services; Drug Therapy, Combination; Evidence-Based Medicine; Health Policy; History, 20th Century; History, 21st Century; Humans; Kenya; Legislation, Drug; Malaria; Practice Guidelines as Topic; Sesquiterpenes | 2007 |
Eurycoma longifolia extract-artemisinin combination: parasitemia suppression of Plasmodium yoelii-infected mice.
Topics: Animals; Antimalarials; Artemisinins; Eurycoma; Malaria; Mice; Parasitemia; Plant Extracts; Plant Roots; Plants, Medicinal; Plasmodium yoelii | 2007 |
Haemoglobinuria in a 38-year-old French expatriate man living in Cameroon following artemisinin-based antimalarial treatment.
Topics: Adult; Antimalarials; Artemisinins; Cameroon; Diagnosis, Differential; France; Hemoglobinuria; Humans; Malaria; Male; Travel | 2007 |
Estimating antimalarial drugs consumption in Africa before the switch to artemisinin-based combination therapies (ACTs).
Topics: Antimalarials; Artemisinins; Chloroquine; Drug Therapy; Drug Therapy, Combination; Humans; Malaria; Malawi; Pyrimethamine; Rwanda; Senegal; Sulfadoxine; Tanzania; Zimbabwe | 2007 |
The costs of introducing artemisinin-based combination therapy: evidence from district-wide implementation in rural Tanzania.
Topics: Antimalarials; Artemisinins; Drug Therapy, Combination; Evidence-Based Medicine; Health Care Costs; Humans; Malaria; Policy Making; Rural Health; Tanzania | 2008 |
Polymorphism of antimalaria drug metabolizing, nuclear receptor, and drug transport genes among malaria patients in Zanzibar, East Africa.
Topics: Antimalarials; Artemisinins; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Child, Preschool; Cytochrome P-450 Enzyme System; Female; Humans; Malaria; Male; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Pregnane X Receptor; Receptors, Steroid; Tanzania | 2008 |
From chloroquine to artemether-lumefantrine: the process of drug policy change in Zambia.
Topics: Antimalarials; Artemisinins; Chloroquine; Drug Therapy, Combination; Ethanolamines; Fluorenes; Health Planning Guidelines; Health Policy; Humans; Lumefantrine; Malaria; Zambia | 2008 |
Malaria control in South Africa - challenges and successes.
Topics: Anti-Infective Agents; Antimalarials; Artemisinins; Chloroquine; History, 19th Century; History, 20th Century; HIV Infections; Humans; Malaria; Mosquito Control; South Africa; Travel | 2007 |
Why don't health workers prescribe ACT? A qualitative study of factors affecting the prescription of artemether-lumefantrine.
Topics: Adult; Antimalarials; Artemether; Artemisinins; Case Management; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Government Programs; Guideline Adherence; Health Personnel; Humans; Kenya; Lumefantrine; Malaria; Male; Middle Aged; Rural Population; Surveys and Questionnaires | 2008 |
Plasmodium chabaudi: efficacy of artemisinin + curcumin combination treatment on a clone selected for artemisinin resistance in mice.
Topics: Administration, Oral; Alkaloids; Animals; Anti-Infective Agents; Artemisinins; Benzodioxoles; Biological Availability; Curcumin; Drug Resistance; Drug Therapy, Combination; Malaria; Male; Mice; Parasitemia; Piperidines; Plasmodium chabaudi; Polyunsaturated Alkamides | 2008 |
Promoting the social value of research in Kenya: examining the practical aspects of collaborative partnerships using an ethical framework.
Topics: Academies and Institutes; Anti-Infective Agents; Antimalarials; Artemisinins; Community-Institutional Relations; Cooperative Behavior; Drug Therapy, Combination; Ethics, Research; Haemophilus Vaccines; Health Policy; Humans; Information Dissemination; Interviews as Topic; Kenya; Malaria; Policy Making; Social Values | 2008 |
Drug subsidy could help Tanzania tackle malaria.
Topics: Adult; Anti-Infective Agents; Antimalarials; Artemisinins; Child, Preschool; Female; Fund Raising; Hospital Mortality; Humans; Infant; Malaria; Mother-Child Relations; Pediatrics; Poverty; Rural Health Services; Tanzania | 2008 |
The treatment of falciparum malaria.
Topics: Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Humans; Malaria; Mefloquine; Plasmodium falciparum; Quinidine; Quinine; Quinolines; Sesquiterpenes | 1984 |
[Effect of qinghaosu by rectal administration in the treatment of vivax malaria].
Topics: Antimalarials; Artemisinins; Humans; Malaria; Plasmodium vivax; Sesquiterpenes; Suppositories | 1984 |
[Research on the dose regime of Qinghaosu administration according to its biological half-life].
Topics: Animals; Antimalarials; Artemisinins; Half-Life; Malaria; Mice; Sesquiterpenes | 1984 |
The chemistry and synthesis of qinghaosu derivatives. China Cooperative Research Group on qinghaosu and its derivatives as antimalarials.
Topics: Animals; Antimalarials; Artemisinins; Chemical Phenomena; Chemistry; Malaria; Mice; Plasmodium berghei; Sesquiterpenes | 1982 |
Clinical studies on treatment of cerebral malaria with qinghaosu and its derivatives.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Brain Diseases; Child; Child, Preschool; Female; Humans; Malaria; Male; Middle Aged; Plasmodium falciparum; Sesquiterpenes | 1982 |
[Observation of therapeutic effect of single-dose combined administration of Qinghaosu, sulphomethoxine, pyrimethamine and primaquine in the treatment of chloroquine-resistant malignant malaria (author's transl)].
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria; Male; Middle Aged; Primaquine; Pyrans; Pyrimethamine; Sesquiterpenes; Sulfamethazine | 1981 |
Antimalarial activity of novel ring-contracted artemisinin derivatives.
Topics: Administration, Oral; Animals; Antimalarials; Artemisinins; Drugs, Chinese Herbal; Malaria; Mice; Microbial Sensitivity Tests; Plasmodium berghei; Plasmodium yoelii; Sesquiterpenes; Solubility; Structure-Activity Relationship | 1995 |
Activity of azithromycin as a blood schizonticide against rodent and human plasmodia in vivo.
Topics: Administration, Oral; Animals; Antimalarials; Aotus trivirgatus; Artemisinins; Azithromycin; Disease Models, Animal; Doxycycline; Drug Therapy, Combination; Humans; Injections, Subcutaneous; Malaria; Malaria, Falciparum; Mice; Parasitemia; Phenanthrenes; Plasmodium berghei; Quinine; Sesquiterpenes | 1995 |
Pharmacokinetic and pharmacodynamic aspects of artelinic acid in rodents.
Topics: Absorption; Administration, Oral; Administration, Rectal; Animals; Antimalarials; Artemisinins; Biological Availability; Injections, Intramuscular; Injections, Intravenous; Malaria; Mice; Plasmodium berghei; Sesquiterpenes | 1993 |
Antimalarial activity of dihydroartemisinin derivatives by transdermal application.
Topics: Administration, Cutaneous; Animals; Antimalarials; Artemether; Artemisinins; Gels; Malaria; Mice; Plasmodium berghei; Sesquiterpenes; Structure-Activity Relationship | 1994 |
Artemisinin. Proceedings of a meeting convened by the Wellcome Trust. 25-27 April 1993, Worcestershire, UK.
Topics: Animals; Antimalarials; Antiprotozoal Agents; Artemisinins; Drugs, Chinese Herbal; Humans; Malaria; Sesquiterpenes | 1994 |
Artemisinin: current status.
Topics: Antimalarials; Antiprotozoal Agents; Artemisinins; Artesunate; Drugs, Chinese Herbal; Humans; Malaria; Sesquiterpenes | 1994 |
Comparison of in vivo and in vitro antimalarial activity of artemisinin, dihydroartemisinin and sodium artesunate in the Plasmodium berghei-rodent model.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Malaria; Mice; Plasmodium berghei; Rats; Rats, Wistar; Sesquiterpenes | 1994 |
New, antimalarial, tricyclic 1,2,4-trioxanes: evaluations in mice and monkeys.
Topics: Animals; Antimalarials; Aotus trivirgatus; Artemisinins; Bridged-Ring Compounds; Heterocyclic Compounds; Malaria; Malaria, Falciparum; Mice; Molecular Structure; Plasmodium berghei; Sesquiterpenes | 1994 |
Syntheses and antimalarial activities of N-substituted 11-azaartemisinins.
Topics: Animals; Antimalarials; Artemisinins; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Magnetic Resonance Spectroscopy; Malaria; Mass Spectrometry; Mice; Molecular Structure; Plasmodium berghei; Plasmodium falciparum; Sesquiterpenes; Structure-Activity Relationship | 1995 |
East meets west for improved antimalarials.
Topics: Antimalarials; Artemisinins; Drugs, Chinese Herbal; Humans; Malaria; Sesquiterpenes | 1996 |
The chemotherapy of rodent malaria. LIII. 'Fenozan B07' (Fenozan-50F), a difluorinated 3,3'-spirocyclopentane 1,2,4-trioxane: comparison with some compounds of the artemisinin series.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Drug Synergism; Malaria; Male; Mice; Parasitemia; Peroxides; Plasmodium; Plasmodium berghei; Plasmodium yoelii; Sesquiterpenes; Spiro Compounds | 1997 |
Antimalarial activity of new dihydroartemisinin derivatives. 7. 4-(p-substituted phenyl)-4(R or S)-[10(alpha or beta)-dihydroartemisininoxy]butyric acids.
Topics: Animals; Antimalarials; Artemisinins; Drug Design; Female; Magnetic Resonance Spectroscopy; Malaria; Mice; Molecular Conformation; Molecular Structure; Parasitemia; Plasmodium berghei; Plasmodium falciparum; Sesquiterpenes; Solubility | 1997 |
Herbal remedies for malaria.
Topics: Adult; Antimalarials; Artemisinins; Child; Developing Countries; Humans; Malaria; Phytotherapy; Research; Sesquiterpenes; World Health Organization | 1997 |
Report on the 8th European congress of Clinical Microbiology and Infectious Diseases, Lausanne, Switzerland May 25-28, 1997.
Topics: Antimalarials; Artemisinins; Communicable Diseases; Europe; Hepatitis B; HIV Infections; Humans; Leishmaniasis; Malaria; Microbiology; Sesquiterpenes; Travel; Vaccination | 1997 |
The chemotherapy of rodent malaria. LV. Interactions between pyronaridine and artemisinin.
Topics: Animals; Antimalarials; Artemisinins; Drug Combinations; Drug Resistance; Drug Synergism; Malaria; Mice; Naphthyridines; Plasmodium yoelii; Sesquiterpenes | 1997 |
The chemotherapy of rodent malaria. LVI. Studies on the development of resistance to natural and synthetic endoperoxides.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Drug Resistance; Malaria; Male; Mice; Peroxides; Plasmodium berghei; Plasmodium yoelii; Sesquiterpenes | 1999 |
Synthesis and antimalarial activity of artemisinin derivatives containing an amino group.
Topics: Administration, Oral; Animals; Antimalarials; Artemisinins; Heterocyclic Compounds, 4 or More Rings; Injections, Subcutaneous; Malaria; Mice; Plasmodium berghei; Sesquiterpenes; Structure-Activity Relationship | 2000 |
Potent in vivo antimalarial activity of 3,15-di-O-acetylbruceolide against Plasmodium berghei infection in mice.
Topics: Animals; Antimalarials; Artemisinins; Carbolines; Chloroquine; Dose-Response Relationship, Drug; Malaria; Male; Mice; Mice, Inbred ICR; Plasmodium berghei; Pyridones; Random Allocation; Sesquiterpenes | 2000 |
Re.: Complex, and large, trials of pragmatic malaria interventions.
Topics: Antimalarials; Artemisinins; Clinical Trials as Topic; Humans; Malaria; Sesquiterpenes | 2001 |
Controlling malaria: challenges and solutions.
Topics: Advisory Committees; Africa South of the Sahara; Antimalarials; Artemisinins; Biomarkers; Drug Resistance; Drug Therapy, Combination; Endpoint Determination; Epidemiologic Research Design; Humans; Malaria; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Sesquiterpenes; Treatment Outcome; World Health Organization | 2001 |
In vitro beta-hematin formation assays with plasma of mice infected with Plasmodium yoelii and other parasite preparations: comparative inhibition with quinoline and endoperoxide antimalarials.
Topics: Animals; Antimalarials; Artemisinins; Biological Assay; Dose-Response Relationship, Drug; Erythrocytes; Hemeproteins; Hemin; In Vitro Techniques; Malaria; Male; Mice; Parasitemia; Peroxides; Plasmodium yoelii; Quinolines; Sesquiterpenes | 2001 |
Mechanism-based design of parasite-targeted artemisinin derivatives: synthesis and antimalarial activity of new diamine containing analogues.
Topics: Animals; Antimalarials; Artemisinins; Heterocyclic Compounds, 4 or More Rings; Malaria; Male; Mice; Piperazines; Plasmodium berghei; Plasmodium falciparum; Sesquiterpenes | 2002 |
[Studies on the antimalarial action of gelatin capsule of Artemisia annua].
Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Child; Child, Preschool; Drugs, Chinese Herbal; Female; Gelatin; Humans; Lethal Dose 50; Malaria; Malaria, Vivax; Male; Mice; Middle Aged; Plasmodium berghei; Recurrence; Sesquiterpenes | 1992 |
Rediscovering wormwood: qinghaosu for malaria.
Topics: Antimalarials; Artemisinins; Drugs, Chinese Herbal; Humans; Malaria; Sesquiterpenes | 1992 |
[The blood schizontocidal effects of pyronaridine, amodiaquine, mefloquine and qinghaosu on mice infected with Plasmodium berghei].
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Drug Resistance; Female; Malaria; Male; Mefloquine; Mice; Naphthyridines; Plasmodium berghei; Sesquiterpenes | 1992 |
Stereoselective synthesis and antimalarial activity of alpha-artelinic acid from artemisinin.
Topics: Animals; Antimalarials; Artemisinins; Macaca mulatta; Malaria; Plasmodium knowlesi; Sesquiterpenes | 1992 |
Comparison of effects of pyronaridine, amodiaquine, mefloquine and qinghaosu on rodent malaria.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Drug Administration Schedule; Drug Evaluation, Preclinical; Drug Resistance; Female; Malaria; Male; Mefloquine; Mice; Naphthyridines; Plasmodium berghei; Sesquiterpenes | 1992 |
Drug use and design in the nineties.
Topics: Aminoquinolines; Amodiaquine; Antimalarials; Artemisinins; Calcium Channel Blockers; Chloroquine; Humans; Malaria; Mefloquine; Naphthoquinones; Phenanthrenes; Primaquine; Quinine; Sesquiterpenes; Sulfadoxine | 1991 |
Study of the gametocytocidal/sporontocidal action of qinghaosu (artemisinin) by electron microscopy.
Topics: Animals; Anopheles; Antimalarials; Artemisinins; Drugs, Chinese Herbal; Macaca mulatta; Malaria; Microscopy, Electron, Scanning; Plasmodium; Sesquiterpenes | 1990 |
Synthesis and antimalarial activity of (+)-deoxoartemisinin.
Topics: Animals; Antimalarials; Artemisinins; Chemical Phenomena; Chemistry; Malaria; Mice; Sesquiterpenes; Stereoisomerism; Structure-Activity Relationship | 1990 |
Plasmodium berghei: the antimalarial action of artemisinin and sodium artelinate in vivo and in vitro, studied by flow cytometry.
Topics: Administration, Oral; Animals; Antimalarials; Artemisinins; DNA; Drugs, Chinese Herbal; Flow Cytometry; Injections, Subcutaneous; Malaria; Mice; Plasmodium berghei; Sesquiterpenes | 1990 |
The potentiating action of tetrandrine in combination with chloroquine or qinghaosu against chloroquine-sensitive and resistant falciparum malaria.
Topics: Alkaloids; Animals; Antimalarials; Artemisinins; Benzylisoquinolines; Chloroquine; Drug Resistance; Drug Synergism; Malaria; Plasmodium falciparum; Sesquiterpenes; Species Specificity | 1989 |
Qinghaosu, dietary vitamin E, selenium, and cod-liver oil: effect on the susceptibility of mice to the malarial parasite Plasmodium yoelii.
Topics: Animals; Antimalarials; Antioxidants; Artemisinins; Cod Liver Oil; Disease Susceptibility; Drugs, Chinese Herbal; Female; Malaria; Mice; Plasmodium yoelii; Selenium; Sesquiterpenes; Vitamin E Deficiency | 1989 |
Follow-up observation on the therapeutic effects and remote reactions of artemisinin (Qinghaosu) and artemether in treating malaria in pregnant woman.
Topics: Antimalarials; Artemether; Artemisinins; Female; Follow-Up Studies; Humans; Malaria; Pregnancy; Pregnancy Complications, Infectious; Sesquiterpenes | 1989 |
Artemisinin (qinghaosu)--a new gametocytocidal drug for malaria.
Topics: Animals; Anopheles; Antimalarials; Artemisinins; Macaca mulatta; Malaria; Plasmodium; Sesquiterpenes | 1989 |
Qinghaosu, mefloquine, and pyrimethamine-sulfadoxine in falciparum malaria.
Topics: Antimalarials; Artemisinins; Drug Combinations; Humans; Malaria; Mefloquine; Pyrimethamine; Quinolines; Sesquiterpenes; Sulfadoxine | 1985 |
Qinghaosu, mefloquine, and pyrimethamine-sulfadoxine in falciparum malaria.
Topics: Artemisinins; Drug Combinations; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Malaria; Mefloquine; Pyrimethamine; Quinolines; Sesquiterpenes; Sulfadoxine; Sulfanilamides | 1985 |
[The effect of qinghaosu on the PFC and RFC of mice infected with Plasmodium berghei].
Topics: Animals; Antibody-Producing Cells; Antimalarials; Artemisinins; Female; Hemolytic Plaque Technique; Malaria; Male; Medicine, Chinese Traditional; Medicine, East Asian Traditional; Mice; Plants, Medicinal; Plasmodium berghei; Rosette Formation; Sesquiterpenes | 1985 |
[Authentic species of the Chinese herbal drug qinghao].
Topics: Antimalarials; Artemisinins; Drug Contamination; Drugs, Chinese Herbal; Malaria; Plants, Medicinal; Sesquiterpenes | 1987 |
Effect of mefloquine and artemisinin on the sporogonic cycle of Plasmodium berghei ANKA in Anopheles stephensi mosquitoes.
Topics: Animals; Anopheles; Antimalarials; Artemisinins; Female; Insect Vectors; Malaria; Mefloquine; Mice; Plasmodium berghei; Quinolines; Sesquiterpenes | 1988 |
1,2,4-Trioxanes as potential antimalarial agents.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Malaria; Mice; Plasmodium berghei; Plasmodium falciparum; Sesquiterpenes; Structure-Activity Relationship | 1988 |
[Development of a qinghaosu-resistant line of Plasmodium berghei ANKA and N strain].
Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Drug Resistance, Microbial; Malaria; Male; Mice; Plasmodium berghei; Primaquine; Pyrans; Sesquiterpenes | 1986 |
Endoperoxides as potential antimalarial agents.
Topics: Animals; Antimalarials; Artemisinins; Chemical Phenomena; Chemistry; Drug Resistance; Malaria; Mice; Peroxides; Plasmodium berghei; Plasmodium falciparum; Sesquiterpenes | 1987 |
The chemotherapy of rodent malaria, XL. The action of artemisinin and related sesquiterpenes.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Drug Resistance; Malaria; Male; Mice; Pigments, Biological; Plasmodium berghei; Pyrans; Sesquiterpenes | 1986 |
Effect of artemisinin (qinghaosu) and chloroquine on drug-sensitive and drug-resistant strains of Plasmodium falciparum malaria: use of [2,8-3H]adenosine as an alternative to [G-3H]hypoxanthine in the assessment of in vitro antimalarial activity.
Topics: Adenosine; Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Erythrocytes; Humans; Hypoxanthine; Hypoxanthines; Malaria; Mice; Plasmodium falciparum; Sesquiterpenes | 1987 |
The effect of combinations of qinghaosu (artemisinin) with standard antimalarial drugs in the suppressive treatment of malaria in mice.
Topics: Animals; Antimalarials; Artemisinins; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Malaria; Male; Mice; Plasmodium berghei; Sesquiterpenes | 1987 |
[Control of malaria--chemotherapy and immunoprophylaxis. 1. Chemotherapy].
Topics: Antimalarials; Artemisinins; Drug Combinations; Drug Resistance; Humans; In Vitro Techniques; Malaria; Mefloquine; Plasmodium; Quinolines; Sesquiterpenes; Vaccination | 1986 |
Qinghaosu resistance in rodent malaria.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Malaria; Male; Mice; Plasmodium; Plasmodium berghei; Sesquiterpenes | 1986 |
[Effects of qinghaosu on the surface structure of erythrocytes infected with Plasmodium berghei and the erythrocyte-free parasites].
Topics: Animals; Antimalarials; Artemisinins; Erythrocyte Membrane; Erythrocytes; Malaria; Mice; Plasmodium berghei; Sesquiterpenes | 1986 |
Antimalarial drugs: mode of action and resistance.
Topics: Aminoquinolines; Animals; Anti-Bacterial Agents; Antimalarials; Antimetabolites; Artemisinins; Cell Compartmentation; DNA; Hemin; Humans; Lysosomes; Malaria; Membranes; Plasmodium; Sesquiterpenes | 1986 |
The chemotherapy of rodent malaria, XXXIX. Ultrastructural changes following treatment with artemisinine of Plasmodium berghei infection in mice, with observations of the localization of [3H]-dihydroartemisinine in P. falciparum in vitro.
Topics: Animals; Antimalarials; Artemisinins; Cell Membrane; Endoplasmic Reticulum; Erythrocytes; Malaria; Mice; Microscopy, Electron; Plasmodium berghei; Plasmodium falciparum; Protein Biosynthesis; Ribosomes; Sesquiterpenes; Time Factors | 1985 |
Observation on the efficacy of qinghaosu suppository in 100 cases of falciparum malaria.
Topics: Adolescent; Antimalarials; Artemisinins; Child; Child, Preschool; Female; Humans; Infant; Malaria; Male; Medicine, Chinese Traditional; Medicine, East Asian Traditional; Plant Extracts; Plants, Medicinal; Plasmodium falciparum; Sesquiterpenes; Suppositories | 1985 |
[Development of a piperaquine-resistant line of Plasmodium berghei K 173 strain].
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Malaria; Male; Mefloquine; Mice; Plasmodium berghei; Quinolines; Sesquiterpenes | 1985 |