artemisinin has been researched along with Malaria, Falciparum in 686 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 60 (8.75) | 18.2507 |
| 2000's | 119 (17.35) | 29.6817 |
| 2010's | 387 (56.41) | 24.3611 |
| 2020's | 120 (17.49) | 2.80 |
| Authors | Studies |
|---|---|
| Avery, VM; Duffy, S; Khalaf, AI; Scott, FJ; Suckling, CJ | 1 |
| Berry, P; Campo, B; Cao, J; Ciaravino, V; Easom, EE; Erve, JCL; Freund, YR; Gamo, FJ; Guo, D; Jacobs, RT; Plattner, JJ; Rosenthal, PJ; Sanz, LM; Zhang, YK | 1 |
| Alvarez, S; Arnett, SD; Ball, H; Boshoff, HI; Brothers, RC; Couch, RD; Dowd, CS; Edwards, RL; Girma, M; Haymond, A; Johnson, C; Manikkam, M; McKay, KT; Meyers, MJ; Odom John, AR; Osbourn, DM; Wang, X | 1 |
| Adhikari, N; Gaikwad, VR; Govindarajalu, G; Karale, UB; Krishna, EV; Krishna, VS; Misra, S; Rode, HB; Sijwali, PS; Sriram, D | 1 |
| Augereau, JM; Benoit-Vical, F; Deraeve, C; Jimenez, T; Mustière, R; Nguyen, M; Ouji, M | 1 |
| Akao, Y; Avery, VM; Charman, SA; Chen, G; Chen, X; Chiu, FCK; Cho, N; Crespo, B; Dechering, KJ; Duffy, S; Kamaura, M; Katneni, K; Laleu, B; Lucantoni, L; Ochida, A; Sanz, LM; Shackleford, DM; Sturm, A; Wang, B; White, KL; Wittlin, S | 1 |
| Rosenthal, PJ | 1 |
| Alsayari, A; Badshah, SL; Mabkhot, Y; Noreen, N; Salman, SM; Ullah, A | 1 |
| Anywar, DA; Balikagala, B; Emoto, S; Fukuda, N; Horii, T; Ikeda, M; Katuro, OT; Kimura, E; Mita, T; Odongo-Aginya, EI; Ogwang, M; Opio, W; Palacpac, NMQ; Tachibana, SI; Yamauchi, M | 1 |
| Borrmann, S; Nordmann, T; Ramharter, M | 1 |
| Chookajorn, T; Chotivanich, K; de Cozar, C; Gamo, FJ; Gomez-Lorenzo, MG; Kotanan, N; Kümpornsin, K; Lee, MCS; Loesbanluechai, D; Sanz, LM; White, NJ; Wilairat, P | 1 |
| Amanzougaghene, N; Ashraf, K; Azas, N; Benoit-Vical, F; Bosson-Vanga, H; Cohen, A; Dereuddre-Bosquet, N; Donnette, M; Franetich, JF; Gomez, L; Hutter, S; Lagardère, P; Lavazec, C; Le Grand, R; Lisowski, V; Malzert-Fréon, A; Masurier, N; Mazier, D; Mustière, R; Nguyen, M; Paloque, L; Primas, N; Rault, S; Roques, P; Snounou, G; Soulard, V; Suzanne, P; Tajeri, S; Tefit, M; Vanelle, P; Verhaeghe, P | 1 |
| Chu, CS; Lau, YL; Lee, B; Lee, WC; Nosten, F; Phyo, AP; Rénia, L; Russell, B; Sriprawat, K | 1 |
| Cooper, RA; Kirkman, L | 1 |
| Auparakkitanon, S; Wilairat, P | 1 |
| Bailly, J; Balikagala, B; Clain, J; Coppée, R; Dannaoui, E; Fukuda, N; Georges, H; Hamane, S; Houzé, S; Lavergne, RA; Mazars, E; Mita, T; Odongo-Aginya, EI; Sarrasin, V; Vianou, B; Zinsou, BE | 1 |
| Camara, M; Ferreira, MU; Gil, JP; Morris, U; Nóbrega de Sousa, T; Pernaute-Lau, L | 1 |
| Amaratunga, C; Ashley, EA; Bozdech, Z; Chotivanich, K; Day, NPJ; Dhorda, M; Dondorp, AM; Faiz, A; Ginsburg, H; Hien, TT; Imwong, M; Jittamala, P; Kucharski, M; Lek, D; Lin, K; Mayxay, M; Miotto, O; Nayak, S; Newton, PN; Nguyen, HC; Nguyen, TNT; Nosten, F; Peto, TJ; Phyo, AP; Pukrittayakamee, S; Smithuis, F; Tripathi, J; Tripura, R; van der Pluijm, RW; von Seidlein, L; White, NJ; Zhu, L | 1 |
| Creek, DJ; Dogovski, C; Du, Y; Giannangelo, C; He, W; Li, X; Shami, GJ; Tilley, L; Yang, T; Zhou, W | 1 |
| Jiang, T; Liao, FL; Tu, Y; Wang, J; Wong, YK; Xu, C | 1 |
| Rasmussen, C; Ringwald, P | 1 |
| Abu-Shamma, R; Bienvenu, AL; Bonnot, G; Khamis, F; Lawati, HAAA; Pain, A; Petersen, E; Picot, S; Subudhi, AK | 1 |
| Bassat, Q; Cortés, A; Guetens, P; Millogo, A; Natama, HM; Ouédraogo, DF; Portugaliza, HP; Rosanas-Urgell, A; Rovira-Vallbona, E; Sitoe, A; Somé, AM; Sorgho, H; Tinto, H; Valéa, I; van Hong, N; Varo, R | 1 |
| Abdallah, KS; Bacar, A; Deng, C; Li, G; Li, M; Liu, R; Lu, C; Silai, R; Song, J; Tan, R; Wu, W; Xu, Q; Yuan, Y; Zhang, H; Zheng, S | 1 |
| Bamadio, A; Chico, RM; Cohee, LM; Coumare, S; Dara, A; Diarra, M; Djimde, AA; Doumbo, OK; Kodio, A; Maiga, H; Opondo, C; Sagara, I; Sidibe, B; Tekete, M; Traore, OB; Traore, ZI | 1 |
| Bridgford, JL; Fidock, DA; Ward, KE | 1 |
| Aweeka, F; Ehrlich, H; Freeman, T; French, J; Goodwin, J; Huang, L; Kajubi, R; Kay, K; Li, F; Mwebaza, N; Ou, J; Parikh, S; Riggs, M; Ruiz-Garcia, A; Wade, M; Wang, K | 1 |
| Andreu, D; Arce, EM; Avalos-Padilla, Y; Biosca, A; Bouzón-Arnáiz, I; Caño-Prades, O; Fernàndez-Busquets, X; Moita, D; Muñoz-Torrero, D; Prudêncio, M; Román-Álamo, L; Valle, J | 1 |
| Green, JL; Holder, AA; Kampoun, T; Knuepfer, E; Prommana, P; Shaw, PJ; Srichairatanakool, S; Uthaipibull, C | 1 |
| Anam, Z; Bhattacharjee, S; Chaurasiya, A; Das, G; Dubey, N; Garg, S; Gupta, K; Joshi, N; Joshi, P; Kahlon, AK; Kaushik, S; Kumari, G; Kumari, J; Marothia, M; Maurya, MK; Ranganathan, A; Saini, S; Shoaib, R; Singh, N; Singh, S; Singhal, J; Srivastava, P | 1 |
| Augusto, O; Byamugisha, J; Clerk, C; Dellicour, S; Desai, M; Gomes, M; Guérin, PJ; Hill, J; Kagawa, M; Kariuki, S; Kisinza, W; Manyando, C; McGready, R; Mehta, U; Mosha, D; Mrema, S; Njunju, EM; Nosten, F; Rouamba, T; Rulisa, S; Saito, M; Sevene, E; Singlovic, J; Stepniewska, K; Stergachis, A; Ter Kuile, FO; Tinto, H; Vala, A; van Eijk, AM; Were, E; Yore, M | 1 |
| Barry, AE | 1 |
| Feng, J; Kong, X; Xu, Y; Yan, G; Zhou, S | 1 |
| Barale, JC; Bouillon, A; Chy, S; Eam, R; Kauy, C; Ke, S; Khean, C; Khim, N; Kim, S; Kloeung, N; Kul, C; Leang, R; Mairet-Khedim, M; Ringwald, P; Roesch, C; Srun, S; Witkowski, B | 1 |
| Anywar, DA; Balikagala, B; Fukuda, N; Horii, T; Kimura, E; Miida, T; Mita, T; Odongo-Aginya, EI; Ogwang, M; Palacpac, NMQ; Ueno, T | 1 |
| Ganguly, R; Khaw, LT; Lai, JW; Lim, YAL; Maah, MJ; Ng, CH; Sarip, R; Tan, KW | 1 |
| Assisi, C; Boentoro, J; Bozdech, Z; Dondorp, AM; Dziekan, JM; Kucharski, M; Miotto, O; Mok, S; Nayak, S; van der Pluijm, RW; Wirjanata, G | 1 |
| Barik, TK; Behera, J; Meher, BR; Murmu, LK; Panda, M; Purohit, P | 1 |
| Adjei, GO; Ahorhorlu, SY; Alifrangis, M; Duah-Quashie, NO; Dzudzor, B; Hansson, H; Jensen, RW; Kudzi, W; Nartey, ET; Quashie, NB; Wang, CW; Zoiku, F | 1 |
| Aonsri, C; Boonyalai, N; Bunsermyos, W; Chaorattanakawee, S; Dondorp, AM; Imaram, W; Imwong, M; Kosaisavee, V; Kunasol, C; Mungthin, M; Saunders, D; Suwannasin, K; Thamnurak, C | 1 |
| Akbar, S; Almaliti, J; Bick, DS; Bogyo, M; da Fonseca, PCA; Deni, I; Duffey, M; Fairhurst, KJ; Fidock, DA; Gerwick, WH; Gould, AE; Kirkman, LA; Lin, G; Liu, YJ; Muir, R; Ng, CL; Niles, JC; O'Donoghue, AJ; Park, H; Pasaje, CFA; Stokes, BH; Uhlemann, AC; Ward, KE; Yeo, T; Zhan, W; Zhang, H | 1 |
| Baharav, N; Schwartz, E | 1 |
| Achonduh-Atijegbe, O; Ali, IM; Alifrangis, M; Bigoga, JD; Chedjou, JPK; Cui, L; Evehe, MB; Fomboh, CT; Hansson, H; Hocke, EF; Jørgensen, MHM; Mbacham, WF; Niba, PTN; Nji, AM; Stresman, G | 1 |
| Akala, HM; Amwoma, JG; Andagalu, BM; Chemwor, GC; Cheruiyot, AC; Egbo, TE; Garges, EC; Juma, DW; Juma, JA; Kamau, E; Mwakio, EW; Ogutu, BR; Okoth, RO; Onyango, IA; Opot, BH; Roth, AL; Wakoli, DM; Watson, OJ; Yedah, RA | 1 |
| Baker, DA; Ménard, D; Platon, L | 1 |
| Kamchonwongpaisan, S; Kongkasuriyachai, D; Nosten, F; Pengon, J; Phyo, AP; Posayapisit, N; Shaw, PJ; Uthaipibull, C; Yuthavong, Y | 1 |
| Chaijaroenkul, W; Jalei, AA; Muhamad, P; Na-Bangchang, K | 1 |
| Arnaldo, P; Cancio, B; Chivale, N; da Silva, C; Dias, B; Duarte, D; Enosse, S; Luis, S; Matias, D; Nogueira, F; Salvador, C; Silva, M; Viegas, R | 1 |
| Adams, JH; Casandra, D; Cui, L; Gibbons, J; Oberstaller, J; Otto, TD; Pires, CV; Seyfang, A; Siddiqui, F; Simmons, C; Wang, C; Zhang, M | 1 |
| Bailly, J; Bei, AK; Coppée, R; Diallo, MA; Diédhiou, Y; Dièye, B; Diongue, K; Doderer-Lang, C; Fall, A; Garba, MN; Gaye, A; Mama, A; Mbaye, A; Mbaye, AM; Ménard, D; Ndiaye, D; Ndiaye, IM; Ndiaye, T; Thiaw, AB; Tine, A; Yade, MS | 1 |
| Chotivanich, K; Dondorp, AM; Hanboonkunupakarn, B; Kobylinski, KC; Kümpornsin, K; Lee, MCS; Lek, D; Sattabongkot, J; Tarning, J; Tipthara, P; Tripura, R; White, NJ; Yipsirimetee, A | 1 |
| Chen, J; Cheng, G; Gao, P; Gu, L; Krishna, S; Wang, C; Wang, J; Wong, YK; Xiao, W; Yang, DH | 1 |
| Choosri, N; Dondorp, AM; Pan-Ngum, W; Saralamba, S; Simpson, JA; White, L; White, NJ | 1 |
| Alam, MS; Faiz, A; Haldar, K; Haque, R; Islam, MN; Khan, WA; Koepfli, C; Lobo, NF; Phru, CS | 1 |
| Buncherd, H; Imwong, M; Jitueakul, S; Sanmoung, W; Sawangjaroen, N; Thanapongpichat, S; Tun, AW | 1 |
| Jakhan, J; Kojom Foko, LP; Moun, A; Narang, G; Singh, V; Tamang, S | 1 |
| Abdelkader, O; Boulotigam, K; Djimadoum, M; Djimrassengar, H; Doderer-Lang, C; Hassoumi, M; Issa, AH; Issa, MS; Mahamat, MHT; Menard, D; Ndihiokubwayo, JB; Rasmussen, C; Saleh, IDM; Warsame, M | 1 |
| Akhter, M; Chakraborti, S; Chaudhary, P; Dixit, R; Goyal, B; Gupta, S; Kapoor, N; Kumar, B; Pande, V; Pandey, KC; Pasupureddy, R; Shoaib, R; Singh, OP; Singh, S; Vashisht, K | 1 |
| Assefa, A; Bailey, JA; Brhane, BG; Crudal, RM; Cunningham, J; Feleke, SM; Fola, AA; Hennelly, CM; Juliano, JJ; Mamo, H; Mohammed, H; Parr, JB; Petros, B; Reichert, E; Solomon, H; Tasew, G | 1 |
| Amaratunga, C; Boon, WPC; de Haan, F; Dondorp, AM; Lek, D; Moors, EHM; Orng, LH; Quang, TN; Thi, VAC; Vonglokham, M | 1 |
| Chim-Ong, A; Kalamuddin, M; Li, X; Lucky, AB; Miao, J; Shakri, AR; Wang, C | 1 |
| Abugri, J; Amon, D; Aniweh, Y; Ansah, F; Ashitei, S; Awandare, GA; Ayeke, D; Binka, FN; Boyetey, MB; Chirawurah, JD; Dinko, B; Kornu, VE; Kweku, M; Laryea, R; Nyame, K; Opoku, N; Owusu, R; Owusu-Appiah, C; Razak, N; Sutherland, CJ | 1 |
| Bakri, A; Benito, A; Berzosa, P; Chol, BT; García, L; Gisbert, FB; González, V; Julla, A; Molina-de la Fuente, I; Nanclares, C; Ousley, J; Sagrado Benito, MJ | 1 |
| Greenwood, B | 1 |
| D'Alessandro, U; Dabira, ED; Diakite, H; Djimde, M; Dorlo, TP; Erhart, A; González, R; Kabore, B; Kayentao, K; Keita, M; Macuacua, S; Menendez, C; Mens, P; Muhindo, HM; Piqueras, M; Sagara, I; Schallig, H; Sevene, E; Tinto, H; Traore, M; Tshiongo, JK; Vala, A | 1 |
| Bhattacharjee, S; Karmodiya, K; Pandit, K; Surolia, N | 1 |
| Acharya, S; Arnold, L; Chico, RM; Gore-Langton, GR; Lufele, E; Moore, BR; Price, RN; Rogerson, SJ; Ter Kuile, FO; Thriemer, K; Unger, HW; van Eijk, AM; Wu, C | 1 |
| Chenet, SM; Huyhua-Gutiérrez, S; Rojas, LM; Saavedra-Samillán, M; Sandoval-Bances, J; Tapia-Limonchi, R; Tejada-Muñoz, S | 1 |
| Triunfol, M | 1 |
| Amaratunga, C; Boon, WPC; Cao, VAT; de Haan, F; Dondorp, AM; Le Quyen, D; Moors, EHM; Nguyen, TQ | 1 |
| Huang, Y; Li, Y; Liu, X; Qin, X; Si, W; Sun, J; Yan, X; Yu, J; Zhang, Q; Zhao, Y | 1 |
| Capuano, R; Di Natale, C; Pain, A; Stead, Z | 1 |
| Borchardt, C; Foroutan, B; Markoff, S; Wilk-Vollmann, S | 1 |
| Abuaku, B; Bruku, S; Duah-Quashie, NO; Fox, A; Koram, KA; Letizia, A; Matrevi, SA; Opoku-Agyeman, P; Quashie, NB | 1 |
| Amambua-Ngwa, A; Amato, R; Amenga-Etego, L; Andagalu, B; Apinjoh, T; Bouyou-Akotet, M; D'Alessandro, U; Djimde, AA; Ghansah, A; Golassa, L; Ishengoma, D; Jeffries, D; Kamau, E; Kolapo, O; Kwiatkowski, D; Maïga-Ascofaré, O; Mane, K; Randrianarivelojosia, M; Simpson, V; Worwui, A; Yavo, W | 1 |
| Guérin, PJ; Kennon, K; Mansoor, R; McGready, R; Nosten, F; Saito, M; Stepniewska, K | 1 |
| Ayong, L; Ebong, SB; Eboumbou Moukoko, CE; Epee Eboumbou, P; Garke, B; Huang, F; Kojom Foko, LP; Nsango, SE; Sitchueng, L; Yan, H | 1 |
| Bienvenu, AL; Bonnot, G; Kouakou, YI; Lavoignat, A; Leboucher, G; Picot, S; Tod, M | 1 |
| Buncherd, H; Khammanee, T; Sawangjaroen, N; Thanapongpichat, S; Tun, AW | 2 |
| Baum, J; Georgiou, P; Malpartida-Cardenas, K; Miscourides, N; Moser, N; Rodriguez-Manzano, J; Yu, LS | 1 |
| Emran, NA; Lin, Z; Zaw, MT | 1 |
| Chhibber-Goel, J; Sharma, A | 1 |
| Anderson, TJC; Button-Simons, K; Cheeseman, IH; Emrich, S; Ferdig, MT; Haile, M; Kappe, SHI; Kumar, S; Li, X; McDew-White, M; Nosten, F; Vaughan, AM | 1 |
| Fotoran, WL; Irvine, DJ; Kleiber, N; Liebau, E; Miranda, BNM; Müntefering, T; Wunderlich, G | 1 |
| Aluvaala, E; Chege, WK; Judah, T; Kiboi, D; Kiiru, JN; Kimani, FT; Musyoka, KB; Nganga, JK; Omondi, P | 1 |
| Bridgford, JL; Cobbold, SA; Dixon, MW; Duffy, MF; Gillett, DL; McConville, MJ; McMillan, PJ; Ralph, SA; Tilley, L; Tutor, MV; Xie, SC; Yang, T; Yeoh, LM | 1 |
| D'Alessandro, U; Dahal, P; Guerin, PJ; Price, RN; Simpson, JA; Stepniewska, K | 1 |
| Allen, H; Chamroeun, S; Daro, K; Kunthy, S; MacDonald, A; Mundy, G; Panharith, N; Poyer, S; Pratt, A; Ra, S; Samean, S; Sarath, M; Sochea, P; Sovottha, C; Thomson, R; Yeung, S | 1 |
| Abdallah, R; Louzada, J; Lucchi, NW; Oliveira-Ferreira, J; Udhayakumar, V | 1 |
| Bártfai, R; Bergmann, B; Birnbaum, J; Blancke Soares, A; Flemming, S; Fröhlke, U; Herrmann, H; Hoeijmakers, WAM; Jonscher, E; Mesén-Ramírez, P; Sabitzki, R; Scharf, S; Schmidt, S; Schmitt, M; Spielmann, T; Toenhake, CG | 1 |
| Aweeka, F; Huang, L; Hughes, E; Kajubi, R; Mwebaza, N; Mwima, MW; Nguyen, V; Nyunt, MM; Orukan, F; Parikh, S | 1 |
| Abuaku, B; Anto, F; Aydemir, O; Bailey, J; Ghansah, A; Hathaway, NJ; Marsh, PW; Mensah, BA; Myers-Hansen, JL; Opoku, M | 1 |
| Abdulla, S; Bousema, T; Drakeley, C; Hamad, A; Mbaga, TA; Mihayo, M; Mosha, D; Shekalaghe, S | 1 |
| Anderson, TJC; Button-Simons, KA; Cassady, Z; Checkley, LA; Davis, SZ; Ferdig, MT; Foster, GJ; McDew-White, M; Nosten, FH; Shoue, DA; Sievert, MAC; Singh, PP; Vendrely, KM | 1 |
| Basco, L; Bogreau, H; Diallo, SM; Ould Ahmedou Salem, MS; Ould Khairy, ML; Ould Mohamed Salem Boukhary, A; Papa Mze, N; Parola, P | 1 |
| Boonhok, R; Cabrera, M; Cao, Y; Cui, L; Liang, X; Mbenda, HGN; Miao, J; Min, H; Qin, J; Siddiqui, FA; Wang, M; Zhu, X | 1 |
| Barnes, KI; McGready, R; Mokuolu, O; Nosten, F; White, NJ | 1 |
| Baum, J; Freemont, PS; Lai, HE; Wilkinson, MD | 1 |
| Amaratunga, C; Amato, R; Anvikar, AR; Ashley, E; Baidya, S; Behera, PK; Callery, JJ; Chau, NH; Cheah, PY; Chotivanich, K; Chutasmit, K; Day, NPJ; Dhorda, M; Dondorp, AM; Fairhurst, RM; Faiz, A; Fanello, C; Gantait, K; Ghosh, T; Gonçalves, S; Grobusch, MP; Hanboonkunupakarn, B; Heaton, J; Hien, TT; Hlaing, TM; Hoa, NT; Hoglund, RM; Huy, R; Imwong, M; Jacob, CG; Jittamala, P; Kaewmok, W; Kwiatkowski, DP; Lek, D; Lin, K; Mao, S; Maude, RJ; Mayxay, M; Miotto, O; Mohanty, AK; Mukaka, M; Newton, PN; Onyamboko, M; Oun, S; Pearson, RD; Peto, TJ; Pukrittayakamee, S; Pyae Phyo, A; Runcharern, R; Saelow, C; Satpathi, P; Satpathi, S; Smithuis, F; Sovann, Y; Sreng, S; Suon, S; Tarning, J; Thanh, NV; Thant, M; Thuy-Nhien, NT; Tripura, A; Tripura, R; Ul Islam, A; Valecha, N; van der Pluijm, RW; van Vugt, M; von Seidlein, L; Waithira, N; White, NJ; Winterberg, M; Woodrow, CJ; Yen, S | 1 |
| Kelley, J; L'Episcopia, M; Lucchi, N; Menegon, M; Nour, BY; Nurahmed, AM; Patel, D; Perrotti, E; Ravishankar, S; Schmedes, S; Severini, C; Talha, AA; Talundzic, E | 1 |
| Bal, M; Das, A; Khuntia, HK; Krishna, S; Pati, S; Rana, R; Ranjit, M | 1 |
| Becker, K; Crane, A; Edwards, RL; Fidock, DA; Gnädig, NF; Heimsch, KC; Kalantarov, GF; Kuderjavy, M; Lee, MCS; Mok, S; Odom John, AR; Stokes, BH; Straimer, J; Trakht, IN | 1 |
| Barrett, MP; Hughes, KR; Rennie, MT; Roberts, AB; Simwela, NV; Waters, AP | 1 |
| Day, KP; Duffy, MF; Ghansah, A; Koram, KA; Narh, CA; Oduro, AR; Onwona, CO; Ruybal-Pesántez, S; Tiedje, KE | 1 |
| Chakraborty, A; Chowdhury, P; Dasgupta, AK; Ray, S; Sen, S; Sengupta, S | 1 |
| Adebayo, JO; Adegunloye, AP; Balogun, EA; Ishola, AA; Malomo, SO; Tijjani, H | 1 |
| Augereau, JM; Benoit-Vical, F; Ménard, S; Nguyen, M; Ouji, M; Paloque, L; Reyser, T; Witkowski, B | 1 |
| Ashley, EA; Chan, XHS; Day, NPJ; Dhorda, M; Dondorp, AM; Duanguppama, J; Han, KT; Hlaing, TM; Htut, Y; Huch, C; Imwong, M; Khantikul, N; Kunasol, C; Kwiatkowski, DP; Kyaw, MP; Leang, R; Lek, D; Linn, K; Mayxay, M; Miotto, O; Myo Tun, K; Nguon, C; Nosten, FH; Peto, TJ; Phommasone, K; Phyo, AP; Pongvongsa, T; Promnarate, C; Proux, S; Pukrittayakamee, S; Rekol, H; Saejeng, A; Sawangjaroen, N; Smithuis, FM; Srisutham, S; Sugaram, R; Sutawong, K; Suwannasin, K; Thanapongpichat, S; Thu, AM; Tripura, R; van der Pluijm, RW; von Seidlein, L; Vongpromek, R; White, NJ; Win, AA | 1 |
| Ariey, F; Campagne, P; Criscuolo, A; Fidock, DA; Legrand, E; Mazarati, JB; Mbituyumuremyi, A; Menard, D; Munguti, K; Munyaneza, T; Murindahabi, M; Ndikumana, JM; Ngamije, D; Ringwald, P; Stokes, BH; Umulisa, N; Uwimana, A; Warsame, M | 1 |
| Abd-Rahman, AN; Cascales, L; Chalon, S; Chen, N; Collins, KA; Marquart, L; McCarthy, JS; Möhrle, JJ; Odedra, A; Pasay, C; Pava, Z; Peatey, CL; Rebelo, M; Watts, RE; Webb, L | 1 |
| Bontems, S; Boreux, R; De Mol, P; Hayette, MP; Kabututu, PZ; Kayiba, NK; Mvumbi, DM; Mvumbi, GL; Speybroeck, N; Yobi, DM | 1 |
| Fidock, DA; Mok, S; Wicht, KJ | 1 |
| Huang, F; Liu, H; Nyunt, MM; Plowe, CV; Ringwald, P; Shrestha, B; Takala-Harrison, S; Tang, LH; Zhou, SS; Zhou, XN | 1 |
| Boydston, EA; Fidock, DA; Gnädig, NF; Harding, CR; Herneisen, AL; Lourido, S; Markus, BM; Okombo, J; Petrova, B; Sidik, SM; Ward, KE | 1 |
| Ajibola, O; Amambua-Ngwa, A; Awolola, ST; Idowu, ET; Omidiji, O; Tola, M | 1 |
| De Mol, P; Devleesschauwer, B; Hayette, MP; Kayiba, NK; Mvumbi, DM; Mvumbi, GL; Okitolonda Wemakoy, E; Rosas-Aguirre, A; Speybroeck, N; Tshibangu-Kabamba, E; Tuan, VP; Yamaoka, Y; Yobi, DM | 1 |
| Bhattacharyya, MK; Bhattacharyya, S; Bulusu, G; Jha, P; Padhi, S; Roy, A; Suthram, N | 1 |
| Amato, R; Auburn, S; Barry, AE; Gonçalves, S; Hetzel, MW; Hirai, M; Hombhanje, F; Ikeda, M; Kwiatkowski, DP; Laman, M; Marfurt, J; Mehra, S; Miotto, O; Mita, T; Mori, T; Mueller, I; Noviyanti, R; Ohashi, J; Pearson, RD; Price, RN; Ringwald, P; Sekihara, M; Tachibana, SI; Tavul, L; Yamauchi, M | 1 |
| Kanyal, A; Karmodiya, K; Lopez-Rubio, JJ; Rawat, M; Sahasrabudhe, A; Vembar, SS | 1 |
| Contreras-Mancilla, J; Delgado-Ratto, C; Fernandez-Miñope, C; Ferrucci, HR; Gamboa, D; Llanos-Cuentas, A; Van Geertruyden, JP | 1 |
| Hassett, MR; Roepe, PD | 1 |
| Felger, I; Halsey, ES; Hastings, IM; Moriarty, LF; Plucinski, MM; Venkatesan, M | 1 |
| Brieger, W; Escalante, AA; Ezema, B; Goldman, I; Habimana, RM; Halsey, ES; Kabera, M; Lucchi, NW; Mangala, JN; Mbituyumuremyi, A; Moriarty, LF; Munguti, K; Munyaneza, T; Murindahabi, M; Musanabaganwa, C; Mutesa, L; Ngamije, D; Pacheco, MA; Piercefield, E; Rucogoza, A; Sandford, R; Svigel, SS; Talundzic, E; Udhayakumar, V; Umulisa, N; Uwimana, A; Venkatesan, M; Zhou, Z | 1 |
| Das, S; Hati, AK; Kar, A; Mandal, S; Manna, S; Saha, B | 1 |
| Bharti, PK; Das, A; Dubey, S; Lahariya, AK; Schneider, KA; Verma, AK; Verma, K | 1 |
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| Ashley, EA; Aung, H; Aung, Y; Day, NPJ; Dondorp, AM; Heaton, J; Hlaing, T; Imwong, M; Indrasuta, C; Khant, ZS; Kyaw, TT; Maung, SM; McLean, ARD; Phyo, AK; Smithuis, FM; Soe, K; Swe, MMM; Tun, KM; Tun, NN; von Seidlein, L; White, NJ | 1 |
| Bamadio, A; Djimde, AA; Doumbo, OK; Grivoyannis, A; Maiga, H; Plowe, CV; Sagara, I; Sanogo, K; Tolo, Y; Traore, A; Traore, K; Traore, OB; Traore, ZI | 1 |
| Bei, AK; Ehrlich, HY; Parikh, S; Warren, JL; Weinberger, DM | 1 |
| Anderson, TJ; Ariey, F; Bath, JR; Cunningham, CH; Deni, I; Dhingra, SK; Fidock, DA; Gansané, A; Gnädig, NF; Kabanywanyi, AM; Kolley, O; Leang, R; Legrand, E; Ménard, D; Mok, S; Ndayikunda, C; Ndounga, M; Nosten, F; Nzoumbou-Boko, R; Rosenthal, PJ; Ross, LS; Rubiano, K; Schindler, KA; Smith, SJ; Souleymane, IM; Stokes, BH; Straimer, J; Striepen, J; Uwimana, A; Ward, KE; Warsame, M; Yeo, T | 1 |
| Adams, JH; Adapa, SR; Boyapalle, S; Button-Simons, K; Casandra, D; Ferdig, MT; Jiang, RHY; Mayho, M; Oberstaller, J; Otto, TD; Rayner, JC; Thomas, P; Wang, C; Xu, S; Zhang, M | 1 |
| Dass, S; Deobagkar, D; Deshpande, P; Kanyal, A; Karmodiya, K; Ozarkar, A | 1 |
| Bozdech, Z; Casas-Vila, N; Conway, DJ; Cortés, A; Llinás, M; Michel-Todó, L; Russell, TJ; Tintó-Font, E | 1 |
| Creek, DJ; Russell, AS; Siddiqui, G; Srivastava, A | 1 |
| Feng, ZC; Hu, T; Li, SJ; Liu, Y; Sun, YX; Tang, J; Wang, JJ; Wang, XY; Xu, BL; Yang, CY; Yu, YM; Zhang, HW; Zhou, RM | 1 |
| Etoka-Beka, MK; Jeyaraj, S; Kokou, KC; Koukouikila-Koussounda, F; Nguetse, CN; Nkonganyi, CN; Ntoumi, F; Velavan, TP | 1 |
| Eisele, TP; Steketee, RW | 1 |
| Benoit, N; Bercion, R; Diatta, B; Diawara, S; Fall, B; Fall, KB; Fall, M; Gueye, MW; Kounta, MB; Lo, G; Madamet, M; Nakoulima, A; Pradines, B; Wade, KA | 1 |
| Combrinck, JM; Cooper, RA; Cowell, AN; Dhingra, SK; Egan, TJ; Fidock, DA; Gupta, P; Henrich, PP; Hoke, JM; Mok, S; Okombo, J; Redhi, D; Stegman, ML; Winzeler, E; Yeo, T | 1 |
| Chatterjee, M; Ganguly, S; Guha, SK; Maji, AK; Saha, P | 1 |
| Ang, X; Bifani, P; Bodenreider, C; Bonamy, GMC; Chavchich, M; Dembele, L; Diagana, TT; Edstein, MD; Fidock, DA; Lim, MY; Nosten, F; Russell, BM; Selva, JJ; Straimer, J; Yeung, BKS | 1 |
| Balasubramanian, S; Chann, S; Char, M; Gosi, P; Ittiverakul, M; Kuntawunginn, W; Lanteri, CA; Lin, JT; Lon, C; Meshnick, SR; My, M; Rahman, R; Saunders, DL; Sok, S; Spring, MD; Thay, K; Ubalee, R | 1 |
| Cai, TY; Ji, JB; Xing, J; Zhang, YR | 1 |
| Nosten, F | 1 |
| Augereau, JM; Benoit-Vical, F; Paloque, L | 1 |
| D'Alessandro, U; Djimdé, AA; Dorsey, G; Karema, C; Mårtensson, AA; Ndiaye, JL; Olliaro, PL; Zwang, J | 1 |
| Clark, RL | 1 |
| Deponte, M; Djuika, CF; Lanzer, M; Sanchez, CP; Staudacher, V | 1 |
| Alokozai, A; Baktash, SH; Buhler, C; Cundill, B; Hasanzai, A; Laurent, B; Leslie, T; Mayan, I; Mikhail, A; Mohammed, N; Rahimi, HU; Rowland, M; Whitty, CJM; Willey, B; Wood, M | 1 |
| Bogyo, M; Fidock, DA; Ng, CL | 1 |
| Ako, AB; Basco, LK; Djaman, JA; Ngane, VF; Olefongo, D; Roman, J; Tahar, R | 1 |
| Cao, P; Cromer, D; Davenport, MP; Khoury, DS; Klonis, N; McCaw, JM; Simpson, JA; Tilley, L; Zaloumis, S | 1 |
| Avery, VM; Duffy, S | 1 |
| Phyo, AP; von Seidlein, L | 1 |
| Blasco, B; Fidock, DA; Leroy, D | 1 |
| Li, S; Liu, Y; Qian, D; Xu, B; Yang, C; Zhang, H; Zhao, Y; Zhou, R | 1 |
| Aung, PZ; Aye, MM; Aye, TT; Bustos, MDG; Cho, C; Galit, S; Han, ET; Han, SS; Hoque, MR; Kyaw, KT; Kyaw, MP; Myint, HW; Nyunt, MH; Oo, HW; Ortega, L; Ringwald, P; San, NA; Soe, MT; Thimasarn, K; Zaw, NN | 1 |
| Alam, MS; Auburn, S; Hossain, ME; Johora, FT; Khan, WA; Ley, B; Marfurt, J; Nima, MK; Price, RN; Thriemer, K | 1 |
| Gibson, LE; Kimmel, DW; Markwalter, CF; Mbambara, S; Mudenda, L; Thuma, PE; Wright, DW | 1 |
| Bailey, JA; Barnett, EJ; Brazeau, NF; Chaorattanakawee, S; Gosi, P; Juliano, JJ; Lanteri, CA; Lin, JT; Lon, C; Meshnick, SR; Norris, LD; Parobek, CM; Parr, JB; Saunders, DL; Spring, MD | 1 |
| Chhun, P; Chy, S; Ek, S; Kak, N; Kheang, ST; Lek, DS; Mao, S; Menard, D; Nguon, S; Sovannaroth, S | 1 |
| Anderson, TJ; Ataíde, R; Beeson, JG; Fowkes, FJI; McLean, A; Moore, K; Nair, S; Nosten, F; Phyo, AP; Powell, R; Simpson, JA; White, M | 1 |
| Aweeka, F; Conrad, MD; Dorsey, G; Foster, M; Havlir, DV; Huang, L; Jagannathan, P; Kakuru, A; Kamya, MR; Legac, J; Mota, D; Nayebare, P; Rosenthal, PJ; Tukwasibwe, S; Tumwebaze, P; Wallender, E; Whalen, M | 1 |
| Roberts, L | 3 |
| Davis, TME; Salman, S; Sugiarto, SR | 1 |
| Dawre, S; Devarajan, PV; Pathak, S; Sharma, S | 1 |
| Chaijaroenkul, W; Na-Bangchang, K; Phompradit, P | 1 |
| Aniweh, Y; Ansah, F; Awandare, GA; Chirawurah, JD; Duodu, S; Nyarko, PB | 1 |
| Ghani, AC; Griffin, JT; Slater, HC; Walker, PGT; Winskill, P | 1 |
| Ashley, EA; Bonnington, CA; Imwong, M; Nosten, F; Parker, DM; Phyo, AP; Proux, S; Sriprawat, K; White, NJ | 1 |
| Delhaes, L; Jeddi, F; L'Ollivier, C; Malvy, D; Millet, P; Piarroux, R; Pradines, B; Receveur, MC; Torrentino-Madamet, M | 1 |
| Bansal, D; Bharti, PK; Bhattacharyya, DR; Mahanta, J; Mohapatra, PK; Parida, P; Sarma, K; Sarmah, NP; Sehgal, R; Singh, N; Sultan, AA | 1 |
| Gilder, ME; Guérin, PJ; McGready, R; Nosten, F; Saito, M | 1 |
| Feng, GH; Liu, HE; Su, PC; Yang, ZQ; Zhang, J; Zou, CY | 1 |
| Adegnika, AA; Cattaneo, C; Duparc, S; Endamne, L; Flohr, L; Groger, M; Hutchinson, D; Kabwende, L; Kim, J; Kremsner, PG; Lell, B; Lötsch, F; Mischlinger, J; Moehrle, J; Mombo-Ngoma, G; Mordmüller, B; Nguyen, TT; Ramharter, M; Remppis, J; Sievers, M; Velavan, TP; Veletzky, L; Zoleko Manego, R | 1 |
| Ashley, EA; Beau, C; Htike, H; Imwong, M; Nosten, F; Phyo, AP; Proux, S; Sriprawat, K; Swe, LL; Thu, AM; Win, KK; Winterberg, M | 1 |
| Davis, TME; Makani, J; Moore, BR; Sugiarto, SR | 1 |
| Bani-Sadr, F; Brunet, A; Cousson, J; Floch, T; Giltat, A; Julien, G; Lebrun, D; N'Guyen, Y; Romaru, J; Toubas, D | 1 |
| Dimbu, PR; Fortes, F; Goldman, I; Halsey, ES; Kelley, J; Ljolje, D; Lucchi, NW; Macaia, A; Nace, D; Plucinski, MM; Ringwald, P; Talundzic, E; Udhayakumar, V | 1 |
| Adam, I; Gasim, GI; Ibrahim, Y | 1 |
| Anywar, DA; Auma, MA; Balikagala, B; Hashimoto, M; Hirai, M; Horii, T; Ikeda, M; Kaneko, M; Kataoka, M; Katuro, OT; Kimura, E; Mita, T; Obwoya, PS; Odongo-Aginya, EI; Ohashi, J; Okello-Onen, J; Olia, A; Palacpac, NMQ; Sakurai-Yatsushiro, M; Sekihara, M; Tachibana, SI; Takahashi, N; Tsuboi, T; Yamauchi, M; Yatsushiro, S | 1 |
| Aye, KH; Aye, MM; Bergstrand, M; Chit, K; Karlsson, MO; Kyaw, MP; Lohy Das, JP; Nyunt, MH; Tarning, J | 1 |
| Hlaing, T; Kumar, B; Maung, TM; Oo, T; Owiti, P; Shewade, HD; Thi, A; Wai, KT; Zachariah, R | 1 |
| Alifrangis, M; Magnussen, P; Osarfo, J; Tagbor, H | 1 |
| Deibert, J; Gueye, NSG; Kobawila, SC; Koukouikila-Koussounda, F; Mouanga, AM; NKombo, M; Ntoumi, F; Vouvoungui, C | 1 |
| Brashear, A; Cabrera, M; Cao, Y; Chookajorn, T; Cui, L; Dong, G; Kemirembe, K; Miao, J; Rosenthal, PJ; Siddiqui, FA; Wang, M; Wang, Z; Yang, Z | 1 |
| Brown, A; Carey, MA; Cooper, JG; Covelli, V; Guler, JL; Haaren, M; Medlock, GL; Papin, JA | 1 |
| Bonsall, MB; El Mouden, C; Khamis, D; Kura, K | 1 |
| Ariey, F; Ashley, E; Blein, S; Dhorda, M; Eam, R; Iannello, A; Kaiser, K; Ken, M; Khean, C; Khim, N; Kim, S; Legrand, E; Ménard, D; Nosten, F; Pachot, A; Souleymane, IM; Tun, KM; Vachot-Ganée, L | 1 |
| Chookajorn, T | 1 |
| Adams, JH; Adapa, SR; Bronner, IF; Brown, J; Casandra, D; Jiang, RHY; Li, S; Liao, X; Mayho, M; Oberstaller, J; Otto, TD; Rayner, JC; Swanson, J; Udenze, K; Wang, C; Zhang, M | 1 |
| Anh, CX; Birrell, GW; Chavchich, M; Edstein, MD; Quang, NN; Rowcliffe, K; Travers, T; van Breda, K | 1 |
| Ellis, J; Lee, R; Meyer, W; Prosser, C | 1 |
| Bacar, A; Deng, C; Fay, MP; Feng, D; Huang, B; Huang, S; Kéké, RA; Li, D; Li, G; Li, XB; Lin, L; Liu, XH; Lu, F; Mohadji, F; Mohamed, M; Msa Mliva, A; Oithik, F; Said Abdallah, K; Song, J; Su, XZ; Tuo, F; Wang, Q; Wang, X; Wellems, TE; Wu, W; Wu, Z; Xu, Q; Xue, L; Yan, H; Yang, T; Zhang, H; Zheng, S; Zhou, J | 1 |
| Assisya, W; Berens-Riha, N; Clowes, P; Froeschl, G; Gerhardt, M; Hoelscher, M; Kroidl, I; Maboko, L; Mwalongo, W; Ntinginya, EN; Saathoff, E | 1 |
| Brasil, P; Daniel-Ribeiro, CT; Ferreira-da-Cruz, MF; Gomes, LR; Lavigne, A; Ménard, D; Peterka, CL | 1 |
| Ataide, R; Fowkes, FJI; Hellard, M; Price, RN; Scott, N; Simpson, JA; Wilson, DP | 1 |
| Bunditvorapoom, D; Chookajorn, T; Chotivanich, K; Cui, L; Kochakarn, T; Kotanan, N; Krasae, T; Kümpornsin, K; Loesbanluechai, D; Miotto, O; Modchang, C; White, NJ; Wilairat, P | 1 |
| Buppan, P; Harnyuttanakorn, P; Jongwutiwes, S; Kuamsab, N; Putaporntip, C; Seethamchai, S | 1 |
| Chen, MN; Deng, Y; Dong, Y; Mao, XH; Sun, AM; Wang, J; Xu, YC | 1 |
| Cao, P; Dini, S; Fowkes, FJI; McCaw, JM; Price, RN; Simpson, JA; van der Pluijm, RW; Zaloumis, S | 1 |
| Birkholtz, LM; Coertzen, D; de Lange, C; Haynes, RK; N'Da, DD; Smit, FJ; Wentzel, JF; Wong, HN | 1 |
| Boncy, J; Existe, AV; Kano, S; Komaki-Yasuda, K; Vincent, JP | 1 |
| Ahombo, G; Dossou-Yovo, LR; Ibara Ottia, R; Kimbassa Ngoma, G; Kobawila, SC; Kouhounina Batsimba, D; Loukabou Bongolo, NC; Louzolo, I; Macosso, L; Malonga-Massanga, A; Mayengue, PI; Niama, RF; Parra, HJ; Pembet Singana, B; Sekangue Obili, G | 1 |
| Baliga, S; Boloor, A; Devi, R; Gai, P; Gai, PP; Jain, A; Kulkarni, SS; Mahabala, C; Mockenhaupt, FP; Rasalkar, R; Shenoy, D; Siegert, K; Tacoli, C; Wedam, J | 1 |
| Das, S; Hati, AK; Roy, S; Saha, B | 1 |
| Akena, D; Kamya, MR; Kinengyere, AA; Nsobya, S; Obuku, E; Ocan, M; Senono, R | 1 |
| Adams, JH; Amaratunga, C; Breglio, KF; Caleon, RL; Chakravarty, S; Deng, B; Diouf, A; Eastman, RT; Engels, TM; Fairhurst, RM; Fay, MP; Fidock, DA; Figan, CE; Gibson, TJ; Gnädig, NF; Gwadz, RW; Han, PK; Hoffman, SL; James, ER; Kaslow, SR; Kite, WA; Krause, MA; Li, S; Liu, A; Long, CA; Melendez-Muniz, VA; Mershon, JP; Miura, K; Moraes Barros, RR; Mu, J; Nishiguchi, EP; Porcella, SF; Rahman, RS; Ricklefs, S; Sá, JM; Salzman, RE; Sim, BKL; Straimer, J; Sturdevant, DE; Su, XZ; Thomas, ML; Tullo, GS; Udenze, K; Velmurugan, S; Wellems, TE; Zhang, M | 1 |
| Heller, LE; Roepe, PD | 1 |
| Bozdech, Z; Day, NPJ; Dondorp, AM; Kwiatkowski, DP; Miotto, O; Mok, S; Nosten, F; Rocamora, FM; Tripathi, J; van der Pluijm, R; Voss, TS; White, NJ; Zhu, L | 1 |
| Hastings, IM; Hodel, EM; Jones, S; Kay, K; Sharma, R | 1 |
| Asua, V; Conrad, MD; Dorsey, G; Kamya, MR; Kigozi, SP; Legac, J; Nsobya, SL; Rosenthal, PJ; Vinden, J | 1 |
| Ashley, EA; Day, NPJ; Dhorda, M; Dondorp, AM; Imwong, M; Intharabut, B; Kingston, HW; Silamut, K; Srinamon, K; Stepniewska, K; White, NJ; Woodrow, C | 1 |
| Beavogui, AH; Borghini-Fuhrer, I; Djimdé, AA; Duparc, S; Felices, M; Funck-Brentano, C; Khan, Y; Ouedraogo, JB; Ouologuem, N; Sagara, I; Sirima, SB; Soulama, I; Voiriot, P | 1 |
| Áreas, A; Castro, AM; Chapadense, F; Cravo, P; Machado, RB; Machado, RLD; Ventura, AMRDS; Viana, GR; Zalis, MG | 1 |
| Buffet, P; Chambrion, C; Chartrel, N; Mouri, O; Ndour, PA; Roussel, C; Smith, B; Smith, P; Thellier, M; Wojnarski, M | 1 |
| Deng, C; Huang, B; Liang, Y; Song, J; Su, Y; Tan, B; Wang, Q; Wu, G; Wu, W; Zhang, H; Zhang, Z; Zhou, C | 1 |
| Nyunt, MM; Plowe, CV; Zainabadi, K | 1 |
| Agrawal, S; Ashley, EA; Fukuda, MM; Han, KT; Hlaing, TM; Huang, F; Jacob, CG; Li, Y; Lon, C; Nyunt, MM; O'Connor, TD; Plowe, CV; Ringwald, P; Saunders, DL; Shetty, AC; Silva, JC; Stewart, KE; Takala-Harrison, S | 1 |
| Dai, BQ; Hou, HP; Ma, LN; Su, P; Ye, ZG; Zhang, GP; Zhang, ZX | 1 |
| Chy, S; Felger, I; Hastings, I; Hodel, EM; Jones, S; Kay, K; Mbituyumuremyi, A; Menard, D; Uwimana, A | 1 |
| Anvikar, A; Goomber, S; Mishra, N; Valecha, N | 1 |
| Huang, F; Li, S; Liu, Y; Lu, D; Qian, D; Wang, H; Yang, C; Zhang, H; Zhao, Y; Zhou, R | 1 |
| Conrad, MD; Rosenthal, PJ | 1 |
| Biswas, A; Das, S; Ganguly, S; Guha, SK; Kundu, PK; Maji, AK; Saha, P | 1 |
| Abe, T; Cui, L; Dinh Tuong, T; Jongwutiwes, S; Kaneko, O; Kyaw, MP; Miao, M; Moji, H; Mu, J; Nakazawa, S; Parker, DM; Pongvongsa, T; Putaporntip, C; Sattabongkot, J; Sirichaisinthop, J; Su, XZ; Wang, Z; Xangsayarath, P; Yan, G; Yang, Z; Yuan, L | 1 |
| Bajad, S; Benjamin, K; Covello, PS; Dang, G; Dengrove, D; Diola, D; Dorin, G; Ellens, KW; Eng, D; Fickes, S; Fisher, K; Fleck, M; Galazzo, J; Gaucher, SP; Geistlinger, T; Henry, R; Hepp, M; Horning, T; Iqbal, T; Jiang, H; Keasling, JD; Kizer, L; Leavell, MD; Lenihan, J; Lieu, B; Lievense, J; Main, A; McPhee, D; Melis, D; Moss, N; Newman, JD; Paddon, CJ; Pitera, DJ; Polichuk, DR; Reed, DW; Regentin, R; Reiling, KK; Renninger, NS; Secrest, S; Tai, A; Teoh, KH; Treynor, T; Tsuruta, H; Vazquez, R; Westblade, LF; Westfall, PJ; Xu, L; Yu, M; Zhang, Y; Zhao, L | 1 |
| Anderson, TJ; McGready, R; Nair, S; Nkhoma, SC; Nosten, F; Phyo, AP; Stepniewska, K | 1 |
| Cooksey, R; Dahlström, S; Fairhurst, RM; Flegg, JA; Guerin, PJ; Johnson, JD; Le Bras, J; Le Nagard, H; Lim, P; Ménard, D; Mentré, F; Murillo, C; Musset, L; Noedl, H; Nosten, F; Nsobya, SL; Pradines, B; Quashie, NB; Sibley, CH; Sinou, V; Sriprawat, K; Woodrow, CJ | 1 |
| Kremsner, PG; Krishna, S | 1 |
| Alcock, D; Almagro-Garcia, J; Amambua-Ngwa, A; Amaratunga, C; Amenga-Etego, L; Anderson, JM; Ariey, F; Asoala, V; Auburn, S; Berriman, M; Bethell, D; Boni, MF; Campino, S; Chuor, CM; Conway, DJ; Day, NP; Djimdé, AA; Dolecek, C; Dondorp, AM; Doumbo, OK; Drury, E; Duong, S; Fairhurst, RM; Fukuda, MM; Gamble, C; Hien, TT; Hodgson, AV; Hubbart, C; Imwong, M; Jyothi, D; Koch, O; Kwiatkowski, DP; Lim, P; Lon, C; Macinnis, B; Manske, M; Maslen, G; McVean, G; Miles, A; Miotto, O; Newbold, CI; Nguon, C; Nosten, F; O'Brien, J; Ouedraogo, JB; Oyola, SO; Plowe, CV; Rayner, JC; Ringwald, P; Rockett, KA; Ruano-Rubio, V; Sanders, M; Saunders, D; Se, Y; Spencer, CC; Sreng, S; Su, XZ; Suon, S; Takala-Harrison, S; Thai, CQ; White, NJ; Zongo, I | 1 |
| Bera, DK; Biswas, A; Das, M; Das, S; Ganguly, S; Guha, SK; Kundu, PK; Maji, AK; Mullick, S; Naskar, A; Ray, K; Saha, P | 1 |
| Neafsey, DE | 1 |
| Culleton, R; Ferreira, PE; Gil, JP; Meshnick, SR | 1 |
| Baruah, I; Dhiman, S; Goswami, D; Rabha, B; Sharma, DK; Singh, L; Veer, V | 1 |
| Bright, AT; Winzeler, EA | 1 |
| Krudsood, S; Tangpukdee, N; Wilairatana, P | 1 |
| Chiodini, PL; Coltart, CE; Doherty, T; Jarvis, JN; Pule, M | 1 |
| Alexander, C; Aman, R; Culleton, R; Ferreira, PE; Hunja, CW; Lumsden, R; Mita, T; Morris, S; Unger, H | 1 |
| Dondorp, AM; Faiz, MA; Hien, TT; Mokuolu, OA; Pukrittayakamee, S; White, NJ | 1 |
| Flegg, JA; Gharbi, M; Guerin, PJ; Hopkins Sibley, C; Metcalf, CJE; Shewchuk, T; Venkatesan, M | 1 |
| Sibley, CH; Wongsrichanalai, C | 1 |
| Abdulla, S; Amuri, M; de Savigny, D; Kajungu, D; Khatib, RA; Masanja, IM; Njozi, M; Selemani, M | 1 |
| D'Alessandro, U; Grobusch, MP; Lutumba, P; Muhindo Mavoko, H; Nabasumba, C; Tinto, H; Van Geertruyden, JP | 1 |
| Bakshi, RP; Nenortas, E; Shapiro, TA; Sullivan, DJ; Tripathi, AK | 1 |
| Cremers, S; Fidock, DA; Henrich, PP; Kyle, DE; O'Brien, C; Sáenz, FE | 1 |
| Ashley, EA; Bethell, D; Björkman, A; Borrmann, S; Diakite, M; Djimde, AA; Dondorp, AM; Fairhurst, RM; Flegg, JA; Guérin, PJ; Hien, TT; Mårtensson, A; Mayxay, M; Newton, PN; Noedl, H; Nosten, F; Phyo, AP; Se, Y; Socheat, D; Stepniewska, K; White, NJ | 1 |
| Batty, KT; Kirkpatrick, CM; Patel, K; Simpson, JA; Zaloumis, S | 1 |
| Plowe, CV | 1 |
| Amaratunga, C; Ariey, F; Barale, JC; Beghain, J; Benoit-Vical, F; Berry, A; Bouchier, C; Bout, DM; Chuor, CM; Duong, S; Duru, V; Fairhurst, RM; Fandeur, T; Genton, B; Khim, N; Kim, S; Langlois, AC; Le Bras, J; Leang, R; Lim, P; Ma, L; Ménard, D; Ménard, S; Mercereau-Puijalon, O; Miotto, O; Ringwald, P; Rogers, WO; Sreng, S; Suon, S; Witkowski, B | 1 |
| Abiola, A; Faye, B; Folly, K; Gaye, O; Lo, AC; Ndiaye, JL; Ndiaye, LA; Ndiaye, M; Sow, D; Sylla, K; Tine, RC | 1 |
| Kolaczinski, J; Macdonald, M; Meek, S | 1 |
| Abdul-Ghani, R; Allam, AF; Farag, HF; Shawky, SM | 1 |
| Enweji, N; Gheysari, F; Kaddumukasa, M; Kamugisha, E; Kironde, F; Sendagire, H; Swedberg, G | 1 |
| Adegoke, CA; Amin, A; Amuasi, JH; Ansong, D; Arnold, F; Bruxvoort, K; Diallo, D; Diap, G; Festo, C; Goodman, C; Hanson, K; Johanes, B; Juma, E; Kalolella, A; Kourgueni, IA; Malam, O; Mann, AG; Mberu, B; Ndiaye, S; Nguah, SB; Ren, R; Rueda, ST; Seydou, M; Taylor, M; Thomson, R; Tougher, S; Wamukoya, M; Willey, BA; Ye, Y | 1 |
| Abay, SM | 1 |
| Barillas, E; Chang, J; Evans, L; Lukulay, P; Marmion, J; Pribluda, VS | 1 |
| Bukirwa, H; Kramer, CV; Nair, S; Sinclair, D; Tharyan, P; Unnikrishnan, B | 1 |
| Li, GX; Wang, W; Wang, YH; Xu, FL; Zhang, XG; Zhao, SS | 1 |
| Juliano, JJ; Taylor, SM | 1 |
| Arinaitwe, E; Bigira, V; Conrad, MD; Dorsey, G; Greenhouse, B; Kakuru, A; Kamya, MR; LeClair, N; Muhindo, M; Rosenthal, PJ; Tappero, JW; Wanzira, H | 1 |
| Chotivanich, K; Chuor, CM; Das, D; Day, NP; Dondorp, AM; Pukrittayakamee, S; Socheat, D; Tripura, R; White, NJ; Yi, P | 1 |
| Chen, K; Cui, L; Fan, Q; Feng, G; Hao, M; Lin, Y; Sun, L; Wu, Y; Yang, Z; Zhao, Z | 1 |
| Angus, B | 1 |
| Benjamin, J; Betuela, I; Davis, TM; Laman, M; Moore, BR; Mueller, I; Padapu, N; Robinson, LJ; Siba, P; Tarongka, N | 1 |
| Bala, N; Betuela, I; Davis, TM; Hetzel, MW; Lavu, EK; Page-Sharp, M; Pulford, J | 1 |
| González-Martínez, C; Lalloo, DG; Mackenzie, I; Pace, C; Ramos-Martín, V; Schmutzhard, J; Terlouw, DJ | 1 |
| Amaratunga, C; Dek, D; Fairhurst, RM; Khim, N; Ménard, D; Miotto, O; Try, V; Witkowski, B | 1 |
| Garner, P; Gelband, H; Graves, PM | 3 |
| Beshir, KB; Bousema, T; Burrow, R; Clark, TG; Gadalla, NB; Hallett, RL; Henriques, G; Johnson, RE; Omar, SA; Sawa, P; Sutherland, CJ; van Schalkwyk, DA | 1 |
| Furunishi, M; Hishiya, N; Kasahara, K; Maeda, K; Mikasa, K; Nakamura, F; Ogawa, T; Uno, K; Yamada, Y; Yonekawa, S; Yoshikawa, M | 1 |
| Bjorge, S; Bunkea, T; Cox, J; Dy Soley, L; Meek, S; Mellor, S; Ngak, S; Ringwald, P; Sintasath, D; Sovannaroth, S; Soy Ty, K | 1 |
| Alifrangis, M; Ariey, F; Menard, D; Mercereau-Puijalon, O; Ringwald, P; Roper, C; Talisuna, A | 1 |
| Feachem, RG; Gosling, RD; Hwang, J; MacArthur, JR; Newby, G; Phillips, AA; Smith Gueye, C; Whittaker, M | 1 |
| Makanga, M | 1 |
| Lindegardh, N; Nosten, F; Ouédraogo, JB; Parikh, S; Rosenthal, PJ; Rouamba, N; Somda, SA; Somé, FA; Tarning, J; Zongo, I | 1 |
| Basilico, N; Bosisio, E; Colombo, E; Dell'Agli, M; Haynes, RK; Magenta, D; Parapini, S; Sangiovanni, E; Taramelli, D | 1 |
| Bailey, JA; Bojang, K; Conrad, MD; Coulibaly, SO; DeConti, DK; Desai, M; Doumbo, OK; Greenwood, BM; Gutman, J; Juliano, JJ; Kariuki, S; Kayentao, K; Mårtensson, A; Mathanga, DP; Meshnick, SR; Moormann, AM; Ngasala, B; Njie, F; Parobek, CM; Rosenthal, PJ; Tagbor, H; Taylor, SM; Ter Kuile, FO; Tshefu, AK; Vulule, JM; Williams, J | 1 |
| Hopkins Sibley, C | 1 |
| Adams, M; Ariey, F; Arze, C; Bailey, J; Bethell, D; Brown, TS; Clark, TG; Cummings, MP; Dondorp, AM; Ferdig, MT; Fuehrer, HP; Fukuda, MM; Hien, TT; Hongvanthong, B; Imwong, M; Jacob, CG; Khan, WA; Khanthavong, M; Kwiatkowski, DP; Kyaw, MP; Lon, C; MacInnis, B; Mayxay, M; Menard, D; Mercereau-Puijalon, O; Miotto, O; Newton, PN; Nhien, NT; Noedl, H; Nosten, F; Nyunt, MH; Nyunt, MM; Pepin, CS; Phyo, AP; Plowe, CV; Ringwald, P; Saunders, DL; Se, Y; Silva, JC; Starzengruber, P; Swoboda, P; Takala-Harrison, S; Tan, JC; Tyner, SD; White, NJ | 1 |
| Ahmed, MA; Bhattacharyya, DR; Bora, K; Goswami, BK; Mahanta, J; Mohapatra, PK; Prakash, A; Sarma, B; Sarma, DK | 1 |
| Abdul-Ghani, R; Beier, JC | 1 |
| Amambua-Ngwa, A; Amenga-Etego, L; Andagalu, B; Andrianaranjaka, VH; Apinjoh, T; Bouyou-Akotet, M; Cornelius, V; Djimde, AA; Ghansah, A; Golassa, L; Ishengoma, D; Johnson, K; Kamau, E; Kwiatkowski, DP; Maïga-Ascofaré, O; Mumba, D; Randrianarivelojosia, M; Tindana, P; Tshefu-Kitoto, A; William, Y | 1 |
| Agomo, C; Agomo, P; Aina, O; Banjo, O; Meremikwu, M; Ntadom, G; Odey, F; Ogala, W; Oguche, S; Ogunrinde, G; Okafor, HU; Okuboyejo, T; Sofola, T; Sowunmi, A; Watila, I | 1 |
| Dahlstrom, S; Ferreira, PE; Franzén, O; Gil, JP; Lum, JK; Nosten, F; Osório, NS; Veiga, MI | 1 |
| Alipon, SC; Bosman, P; Canier, L; Chea, N; Chuor Char, M; De Smet, M; Dysoley, L; Etienne, W; Khim, S; Kim, N; Kindermans, JM; Ménard, D; Nackers, F; Stassijns, J; Van den Bergh, R | 1 |
| Bobogare, A; Cheng, Q; Gray, KA; Gresty, KJ; Hii, J; Taleo, G; Waters, NC; Wini, L | 1 |
| Flores, A; Gwala, J; Harrington, H; MacLaren, D; Massey, PD; McBride, E; Oloifana-Polosovai, H; Ribeyro, E; Speare, C; Speare, R | 1 |
| Amambua-Ngwa, A; Amenga-Etego, L; Andagalu, B; Apinjoh, T; Bouyou-Akotet, M; Campino, S; Djimde, AA; Drury, E; Ghansah, A; Golassa, L; Ishengoma, D; Johnson, K; Kamau, E; Kekre, M; Kwiatkowski, D; MacInnis, B; Maiga-Ascofare, O; Mead, D; Mumba, D; Randrianarivelojosia, M; Tindana, P; Yavo, W | 1 |
| Kalwani, V; Mohanasrinivasan, V; Ravikumar, P; Srivastava, S; Subathra Devi, C; Tandon, A; Verma, P | 1 |
| Ashley, E; Day, NP; Dondorp, A; Drake, T; Guérin, PJ; Lubell, Y; Meek, S; White, LJ; White, NJ | 1 |
| Baker, M; Bousema, T; Cairns, M; D'Alessandro, U; Ferguson, NM; Ghani, AC; Griffin, JT; Hugo, P; Jagoe, G; Okell, LC; Tarning, J; Ubben, D | 1 |
| Culleton, R; Endo, H; Hisaoka, T; Mita, T; Murai, K | 1 |
| Fulakeza, JM; Kamn'gona, RM; Laufer, MK; Mukaka, MF; Nkhoma, SC; Seydel, KB; Sisya, TJ; Taylor, TE; Vareta, JA | 1 |
| Manary, MJ; Winzeler, EA | 1 |
| Achonduh, OA; Cundill, B; Drake, TL; Mangham-Jefferies, L; Mbacham, W; Onwujekwe, O; Wiseman, V | 1 |
| Amaratunga, C; Benoit-Vical, F; Dacheux, M; Duru, V; Fairhurst, RM; Fidock, DA; Gnädig, NF; Gregory, PD; Khim, N; Lam, S; Ménard, D; Mercereau-Puijalon, O; Ramadani, AP; Straimer, J; Urnov, FD; Witkowski, B; Zhang, L | 1 |
| Amaratunga, C; Ashley, EA; Bozdech, Z; Chotivanich, K; Day, NP; Dhorda, M; Dondorp, AM; Fairhurst, RM; Faiz, MA; Ferreira, PE; Hien, TT; Htut, Y; Imwong, M; Kwiatkowski, DP; Lim, P; Lin, Z; Mayxay, M; Miotto, O; Mok, S; Newton, PN; Nguon, C; Nosten, F; Onyamboko, MA; Preiser, PR; Pukrittayakamee, S; Suon, S; Tripura, R; White, NJ; Woodrow, CJ; Yeo, T; Zhu, L | 1 |
| Vogel, G | 1 |
| Brown, TS; Cummings, MP; Djimdé, A; Dondorp, AM; Fukuda, M; Hien, TT; Jacob, CG; Kyaw, MP; Mayxay, M; Noedl, H; Nyunt, MM; Plowe, CV; Silva, JC; Takala-Harrison, S | 1 |
| Anderson, TJ; Cheeseman, IH; McDew-White, M; Nosten, F; Phyo, AP; Sriprawat, K | 1 |
| Kiara, SM; Marsh, K; Mwai, L; Nzila, A; Ochola-Oyier, LI; Okombo, J; Pole, L; Tetteh, KK | 1 |
| Han, ET; Han, SS; Hlaing, T; Kyaw, MP; Nyunt, MH; Oo, HW; Phway, HP; San, KK; Tin-Oo, LL; Tun, T; Wang, B; Zaw, NN | 1 |
| Dutta, P; Khan, SA; Mahanta, J; Sharma, J; Soni, M | 1 |
| Gupta, AK; Saxena, AK | 1 |
| Congpuong, K; Hoonchaiyapoom, T; Inorn, K | 1 |
| Benjamin, JM; Betuela, I; Bona, C; Davis, TM; Davis, WA; Karl, S; Kasian, B; Kattenberg, JH; Koleala, T; Laman, M; Lorry, L; Manning, L; Moore, BR; Mueller, I; Robinson, LJ; Rosanas-Urgell, A; Sambale, N; Siba, PM; Warrel, J; Yadi, G | 1 |
| Almagro-Garcia, J; Amaratunga, C; Amato, R; Amenga-Etego, L; Ashley, EA; Bethell, D; Campino, S; Chotivanich, K; Chuor, CM; Day, NP; Dhorda, M; Dondorp, AM; Drury, E; Fairhurst, RM; Faiz, MA; Fanello, CI; Han, KT; Hongvanthong, B; Htut, Y; Imwong, M; Jacob, CG; Khanthavong, M; Kwiatkowski, DP; Kyaw, MP; Lim, P; MacInnis, B; Manske, M; Mayxay, M; McVean, G; Mead, D; Miotto, O; Mokuolu, OA; Newton, PN; Nguon, C; Nosten, F; Onyamboko, M; Oyola, SO; Phyo, AP; Plowe, CV; Pukrittayakamee, S; Ringwald, P; Spencer, CC; Sreng, S; Stalker, J; Suon, S; Takala-Harrison, S; Thanh, TN; Tran, HT; White, NJ; Woodrow, C | 1 |
| Sibley, CH | 2 |
| Galvani, AP; Ndeffo Mbah, ML; Parikh, S | 1 |
| Boulter, A; Carter, TE; Existe, A; Mulligan, CJ; Okech, BA; Romain, JR; St Victor, JY | 1 |
| Achieng, AO; Akala, HM; Andagalu, B; Chebon, LJ; Cheruiyot, AC; Cheruiyot, J; Ingasia, LA; Juma, DW; Kamau, E; Mbuba, E; Muiruri, P; Mwangoka, G; Ng'ang'a, Z; Ngalah, BS; Ogony, J; Onyango, I; Yeda, RA | 1 |
| Chaccour, C; Del Pozo, JL; Kaur, H | 1 |
| Ichinose, Y; Isozumi, R; Kaneko, A; Kimata, I; Logedi, J; Omar, AH; Uemura, H | 1 |
| Ariey, F; Menard, D | 1 |
| Anderson, TJ; Ashley, EA; Cheah, PY; Day, NP; Dhorda, M; Dondorp, AM; Faiz, MA; Flegg, JA; Grist, EP; Guerin, P; Hlaing, T; Hlaing, TM; Imwong, M; Kyaw, MP; Lin, K; Lwin, KM; Maude, RJ; McDew-White, M; Nair, S; Nosten, F; Plewes, K; Pukrittayakamee, S; Smithuis, F; Tun, KM; White, NJ; Win, AA; Woodrow, CJ | 1 |
| Basu, N; Bera, DK; Dutta, S; Ganguly, S; Kundu, PK; Maji, AK; Saha, P | 1 |
| Wang, MY; Zhao, SM | 1 |
| Dondorp, A; von Seidlein, L | 1 |
| Barnwell, JW; Congpuong, K; Goldman, IF; Kachur, PS; Morton, L; Okoth, SA; Plucinski, MM; Satimai, W; Talundzic, E; Udhayakumar, V; Wongsrichanalai, C | 1 |
| Cavaleri, M; Pelfrene, E; Pinheiro, MH | 1 |
| Bhattacharjee, S; Chotivanich, K; Dondorp, AM; Emrich, S; Estiu, G; Ghorbal, M; Haldar, K; Liu, H; Lopez-Rubio, JJ; Mbengue, A; Mohandas, N; Nguon, C; Njimoh, DL; Pandharkar, T; Pfrender, M; Rizk, SS; Ryan, Y; Stahelin, RV; Wiest, O | 1 |
| Burrows, J | 1 |
| Buza, J; Ishengoma, DS; Shayo, A | 1 |
| Adedeji, ON; Ademowo, OG; Bolaji, OO; Falade, CO; Osonuga, OA | 1 |
| Cravo, P; Culleton, R; Napolitano, H | 1 |
| Adams, M; Bustos, MD; Huang, F; Jacob, CG; Liu, H; Nyunt, MM; Plowe, CV; Ringwald, P; Sun, X; Takala-Harrison, S; Tang, L; Xia, Z; Yang, H; Zhou, S | 1 |
| Abdel-Muhsin, AM; Al-Hamidhi, S; Al-Hashami, Z; Albarwani, HS; AlQamashoui, BA; Babiker, HA; Bakhiet, AM; Beja-Pereira, A; Elagib, AA; Elzaki, SE; Idris, MA | 1 |
| Anderson, T; Ashley, EA; Bethell, D; Cooper, BS; Dondorp, AM; Flegg, JA; Lubell, Y; Nair, S; Nguon, C; Nkhoma, S; Nosten, F; Pan-Ngum, W; Phyo, AP; Plowe, C; Silamut, K; Stepniewska, K; Tripura, R; White, LJ; White, NJ; Wiladpai-ngern, JH | 1 |
| Dar, OA; Heymann, DL; Rokadiya, S | 1 |
| Benjamin, J; Davis, TM; Ibam, C; Karl, S; Kasian, B; Koleala, T; Laman, M; Moore, BR; Mueller, I; Siba, PM; St Pierre, TG; Waltmann, A; Woodward, RC | 1 |
| Buathong, N; Chanarat, N; Chann, S; Chaorattanakawee, S; Chuor, CM; Gosi, P; Heng, TK; Jacob, C; Kong, N; Kuntawunginn, W; Lanteri, CA; Lin, JT; Lon, C; Plowe, C; Prom, S; Saingam, P; Saunders, DL; Se, Y; Sea, D; Sriwichai, S; Sundrakes, S; Takala-Harrison, S; Tangthongchaiwiriya, K; Teja-Isavadharm, P; Tyner, SD; Yingyuen, K; Yom, Y | 1 |
| Bouth, DM; Char, MC; Domergue, A; Duru, V; Khim, N; Kim, S; Leang, R; Menard, D; Ringwald, P; Song, L; Tarning, J; Taylor, WR; Witkowski, B | 1 |
| Bassat, Q; Djimde, A; Hamed, K; Ogutu, B; Stricker, K | 1 |
| Anwar, M; Baktash, SH; Drake, TL; Grieve, E; Hansen, KS; Leslie, TJ; Mayan, I; Mikhail, A; Mohammed, N; Rowland, MW; Whitty, CJ | 1 |
| Allan, EL; Clarke, S; Culzoni, MJ; Dwivedi, P; El Sherbiny, M; Fernández, FM; Green, MD; Hall, Z; Ibe, O; Kaur, H; Mamadu, I; Onwujekwe, O; Schellenberg, D; Swamidoss, I; van Wyk, A; Yeung, S | 1 |
| Ciscato, LF; Lopes, NS; Oliveira, VX; Pinheiro, AA; Silva, AF; Silva, LS; Yoshitake, AM | 1 |
| Conroy, AL; Hawkes, M; John, CC; Kain, KC; Liles, WC; Namasopo, S; Opoka, RO; Zhong, K | 1 |
| Djimde, AA; Hamed, K; Kuhen, K; Makanga, M | 1 |
| Fairhurst, RM | 1 |
| Hastings, IM; Hodel, EM; Kay, K | 1 |
| Malhotra, R; Mutreja, D | 1 |
| Maïga-Ascofaré, O; May, J | 1 |
| Brashear, A; Cabrera, M; Cui, L; Gupta, B; Hu, Y; Kemirembe, K; Li, X; Liang, X; Miao, J; Shrestha, S; Sun, X; Wang, Y; Wang, Z; Wu, Y; Yang, Z; Zhang, Y | 1 |
| d'Alessandro, U; Dahal, P; Dorsey, G; Guerin, PJ; Nsanzabana, C; Price, RN; Sibley, CH; Stepniewska, K; Talisuna, AO | 1 |
| Ibrahim, H; Ibrahim, N; Mazier, D; Nepveu, F; Sabater, AM; Valentin, A | 1 |
| Abdulla, S; Ashley, EA; Bassat, Q; Bethell, D; Björkman, A; Borrmann, S; D'Alessandro, U; Dahal, P; Day, NP; Diakite, M; Djimde, AA; Dondorp, AM; Duong, S; Edstein, MD; Fairhurst, RM; Faiz, MA; Falade, C; Flegg, JA; Fogg, C; Gonzalez, R; Greenwood, B; Guérin, PJ; Guthmann, JP; Hamed, K; Hien, TT; Htut, Y; Juma, E; Lim, P; Mårtensson, A; Mayxay, M; Mokuolu, OA; Moreira, C; Newton, P; Noedl, H; Nosten, F; Ogutu, BR; Onyamboko, MA; Owusu-Agyei, S; Phyo, AP; Premji, Z; Price, RN; Pukrittayakamee, S; Ramharter, M; Sagara, I; Se, Y; Stepniewska, K; Suon, S; Ward, SA; White, NJ; Winstanley, PA | 1 |
| Ariey, F; Beghain, J; Ben Haddou, T; Benoit-Vical, F; Berry, A; Bouchier, C; Iriart, X; Ménard, S; Mercereau-Puijalon, O; Ramadani, AP; Witkowski, B | 1 |
| Adak, T; Dang, AS; Dykes, CL; Lather, M; Sharma, D; Singh, OP | 1 |
| Amaratunga, C; Anderson, JM; Burton, TA; Fairhurst, RM; Fay, MP; Gwadz, RW; Men, S; Miller, B; Miotto, O; Sovannaroth, S; St Laurent, B | 1 |
| Aderoyeje, T; Adewoye, EO; Akano, K; Ayede, AI; Fatunmbi, B; Ntadom, G; Sowunmi, A | 2 |
| Benoit, N; Boussaroque, A; Camara, C; Diatta, B; Diémé, Y; Dionne, P; Fall, B; Fall, KB; Fall, M; Madamet, M; Nakoulima, A; Pradines, B; Wade, B | 1 |
| Cheng, HF; Gao, J; Wang, RL; Zhang, SQ; Zhao, Q | 1 |
| Baird, JK; Boni, MF; Dondorp, AM; Farrar, J; Lam, HM; Nguyen, TD; Olliaro, P; Thwaites, GE; White, NJ | 1 |
| Hughes, AL; Jongwutiwes, S; Kosuwin, R; Kuamsab, N; Putaporntip, C; Seethamchai, S; Sueblinvong, T; Tantiwattanasub, W; Vejakama, P | 1 |
| Croft, SL; Ward, S | 1 |
| Abdallah, KS; Attoumane, R; Bacar, A; Deng, C; Guan, Y; Huang, B; Huang, S; Liu, Y; Lu, F; Mliva, AM; Song, J; Su, XZ; Wang, Q; Xu, Q; Xue, L; Yang, T; Yuan, J; Zheng, S; Zhong, Y; Zhou, J | 1 |
| Akinyi Okoth, S; Barnwell, JW; Ceron, N; Chandrabose, J; Chenet, SM; Huber, CS; Krishnalall, K; Lucchi, NW; Macedo de Oliveira, A; Musset, L; Rahman, R; Talundzic, E; Udhayakumar, V; Venkatesan, M | 1 |
| Akala, HM; Auschwitz, JM; Cheruiyot, AC; Gaona, HW; Hickman, MR; Johnson, JD; Kamau, E; Lee, PJ; Leed, SE; Murthy, T; Okello, CO; Talwar, M; Yeda, RA | 1 |
| Fowkes, FJI; Jittamala, P; McGready, R; Moore, KA; Nosten, F; Paw, MK; Pimanpanarak, M; Rijken, MJ; Simpson, JA; White, NJ; Wiladphaingern, J | 1 |
| Menegon, M; Nour, BY; Nurahmed, AM; Severini, C; Talha, AA | 1 |
| Beeching, NJ; Bell, DJ; Chiodini, PL; Lalloo, DG; Shingadia, D; Whitty, CJM | 1 |
| Chotivanich, K; Hanboonkunupakarn, B; Imwong, M; Kyaw, MP; Pukrittayakamee, S; Win, AA; Woodrow, CJ | 1 |
| Maxmen, A | 1 |
| Kilauzi, AL; Magafu, MG; Magafu, NS; Matchaba-Hove, R; Mulumba, JG; Tamfum, JJ; Tapera, R | 1 |
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| Chookajorn, T; Kümpornsin, K; Wilairat, P | 1 |
| Alano, P; Bertuccini, L; Bopp, SE; Clozel, M; Corey, VC; de Almeida, MJ; Fidock, DA; Kasdin, RG; Le Bihan, A; Lee, MC; Ng, CL; Siciliano, G; Winzeler, EA; Wittlin, S | 1 |
| Cui, L; Hemming-Schroeder, E; Lo, E; Nguyen, J; Oo, W; Yan, G; Yang, Z; Zhou, G | 1 |
| Fidock, DA; Lee, AH | 1 |
| Dondorp, A; Imwong, M; Nakeesathit, S; Nosten, F; Pukrittayakamee, S; Saralamba, N; White, NJ | 1 |
| Boukheng, T; Canavati, SE; de Beyl, CZ; Ly, P; Rang, C; Roca-Feltrer, A; Shafique, M; Sintasath, D; Whittaker, MA | 1 |
| Caillet, C; Guerin, PJ; Newton, PN | 1 |
| Canavati, SE; Lawpoolsri, S; Ly, P; Nguon, C; Peeters Grietens, K; Pukrittayakamee, S; Quintero, CE; Singhasivanon, P; Sintasath, D; Whittaker, MA | 1 |
| Batra, S; Biswas, S; Chauhan, BS; Gunjan, S; Pandey, SK; Singh, S; Singh, SK; Srivastava, K; Tripathi, R | 1 |
| Cabral, L; Cristiano, ML; Lobo, L; Nogueira, F; Sousa, Bd | 1 |
| Karunajeewa, HA; Mueller, I | 1 |
| Dondorp, AM; Fairhurst, RM | 1 |
| Cabezas-Fernández, MT; Giménez-López, MJ; Molina-Arrebola, MA; Pousibet-Puerto, J; Salas-Coronas, J; Sánchez-Crespo, A; Soriano-Pérez, MJ; Vázquez-Villegas, J | 1 |
| Ch'ng, JH; Chan, SC; Eriksson, AB; Liu, J; Masters, E; Moles, E; Moll, K; Quintana, Mdel P; Wahlgren, M | 1 |
| Ackermann, I; Aubin, F; Carn, G; Gesase, S; Lusingu, JPA; Mnkande, E; Mrango, Z; Mtoro, A; Ngocho, JS; Ogutu, B; Onyango, KO; Ouedraogo, A; Sirima, SB; Strub, N; Vanraes, J; Yaro, JB | 1 |
| Assohou, C; Damien, G; Deme, AB; Gazard, DK; Hounkpe, VO; Mama, A; Moutouama, JD; Ndam, NT; Ndiaye, D; Ogouyèmi-Hounto, A; Remoué, F; Tchonlin, D | 1 |
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| Bayingana, C; Gahutu, JB; Gai, PP; Geus, D; Mockenhaupt, FP; Ndoli, J; Sendegeya, A; Sifft, K; Tacoli, C | 1 |
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| Kirchner, S; Power, BJ; Waters, AP | 1 |
| Deibert, J; Etoka-Beka, MK; Kobawila, SC; Kombo, M; Koukouikila-Koussounda, F; Ntoumi, F; Poulain, P; Vouvoungui, C | 1 |
| Cornish, K; Daniell, H; Kalamuddin, M; Kumar, S; Malhotra, K; Malhotra, P; Mohmmed, A; Qureshi, MI; Rawat, K; Subramaniyan, M | 1 |
| Anderson, TJ; Ashley, EA; Day, NP; Dhorda, M; Dondorp, AM; Fairhurst, RM; Faiz, MA; Flegg, JA; Gething, PW; Grist, EP; Guerin, PJ; Hien, TT; Hlaing, TM; Humphreys, G; Imwong, M; Kindermans, JM; Mas, IS; Maude, RJ; Mayxay, M; McDew-White, M; Menard, D; Nair, S; Newton, PN; Nguyen, NT; Nosten, F; Price, RN; Pukrittayakamee, S; Sibley, CH; Smithuis, F; Takala-Harrison, S; Tun, KM; White, NJ; Witkowski, B; Woodrow, CJ | 1 |
| Afonne, C; Ajayi, IO; Balyeku, A; Castellani, J; Diarra, A; Falade, CO; Fouque, F; Gansane, Z; Gomes, M; Jegede, AS; Kabarungi, V; Kyaligonza, J; Nsungwa-Sabiiti, J; Oshiname, FO; Petzold, M; Sanou, AK; Sermé, L; Singlovic, J; Siribié, M; Sirima, SB; Tiono, AB; Yusuf, OB | 1 |
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| Anderson, TJ; Ashley, E; Bilgic, F; Cheeseman, IH; McDew-White, M; McGready, R; Nair, S; Nkhoma, S; Nosten, F; Pyae Phyo, A; White, NJ | 1 |
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| Biliya, S; Daniels, R; Deme, AB; Ndiaye, D; Ndiaye, YD; Olsen, C; Patel, DS; Talundzic, E; Udhayakumar, V; Vannberg, FO; Volkman, SK | 1 |
| Dondorp, AM; Seidlein, LV; Smithuis, FM; Woodrow, C | 1 |
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| Deakin, J; Idris-Usman, M; Matthews, H; Nirmalan, NJ; Rajab, M | 1 |
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| Dondorp, A; Menard, D | 1 |
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| Guan, Y; Tang, L; Wu, S; Zhang, G; Zheng, B | 1 |
| Brittenham, GM; Guoqiao, L; Jianping, S; Krudsood, S; Looareesuwan, S; Pothipak, N; Srivilairit, S; Tangpukdee, N; Thanchatwet, V; Wilairatana, P | 1 |
| Bousema, T; Drakeley, CJ; Ghani, AC; Okell, LC; Sutherland, CJ | 1 |
| Kano, S; Krudsood, S; Looareesuwan, S; Punyapradit, N; Somwong, W; Tangpukdee, N; Wilairatana, P; Yew, HS | 1 |
| Ashley, EA; Balkan, S; Bukirwa, H; Checchi, F; Dorsey, G; Guthmann, JP; Olliaro, P; Pinoges, L; Taylor, WR; Turyakira, E; Urruta, PP; van den Broek, I; van Herp, M; Zongo, I | 1 |
| Barnes, KI; McIntyre, D; Zikusooka, CM | 1 |
| Andrianjafy, T; Juliano, JJ; Raharimalala, LA; Randriamanantena, A; Randrianarivelojosia, M; Raveloson, A; Robert, V | 1 |
| Balogun, ST; Gbotosho, GO; Happi, CT; Sowunmi, A | 1 |
| Drakeley, CJ; Nosten, F; Price, RN; Stepniewska, K; Sutherland, CJ; von Seidlein, L; White, NJ | 1 |
| Fukuda, MM; Noedl, H; Schaecher, K; Se, Y; Smith, BL; Socheat, D | 1 |
| Engl, M; Gluderer, D; Ogwang, M; Ploner, F; Ploner, M; Prugger, C; Wernsdorfer, G; Wernsdorfer, WH | 1 |
| Congpuong, K; Kollaritsch, H; Raffelsberger, J; Sirichaisinthop, J; Wernsdorfer, G; Wernsdorfer, WH | 1 |
| Bousema, T; Drakeley, CJ; Ghani, AC; Okell, LC; Whitty, CJ | 1 |
| Anthony, LC; Eng, D; Horning, T; Keasling, JD; Lenihan, JR; Newman, JD; Paddon, CJ; Regentin, R; Renninger, NS; Tsuruta, H | 1 |
| Aguas, R; Day, NP; Dondorp, AM; Maude, RJ; Pontavornpinyo, W; Saralamba, S; White, LJ; White, NJ; Yeung, S | 1 |
| Atheaya, H; Khan, SI; Kumar, N; Rawat, DS; Sharma, M | 1 |
| Ali, A; Bhattarai, A; Björkman, A; Garcia, M; Kahigwa, E; Mårtensson, A; Msellem, MI; Olumese, P; Petzold, M; Rotllant, G; Strömberg, J | 1 |
| Khaing, W; Kyaw, TT; Lin, K; Myint, MK; Tint, HS; Tun, T; Tun, ZW | 1 |
| Avery, BA; Avery, MA; Chittiboyina, A; Kandhari, SP; Mukherjee, P; Shah, F; Zhang, SQ | 1 |
| Achan, J; D'Alessandro, U; Talisuna, AO; Yeka, A | 1 |
| Song, JP; Tan, B; Trung, TN; Van Phuc, D | 1 |
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| Donegan, S; Garner, P; Olliaro, P; Sinclair, D; Zani, B | 1 |
| de Smet, M; Kindermans, JM; Moon, S; Pérez Casas, C; von Schoen-Angerer, T | 1 |
| Noedl, H; Satimai, W; Socheat, D | 1 |
| Quashie, NB | 1 |
| Boly, MD; Deloron, P; Faucher, JF; Houzé, S; Le Bras, J | 1 |
| Kouyaté, B; Meissner, P; Müller, O; Schirmer, RH; Sié, A | 1 |
| Anstey, N; Ashley, E; Barnes, KI; Binh, TQ; D'Alessandro, U; Day, NP; de Vries, PJ; Dorsey, G; Guthmann, JP; Lee, SJ; Mayxay, M; Newton, PN; Nosten, F; Olliaro, P; Osorio, L; Price, RN; Rowland, M; Smithuis, F; Stepniewska, K; Taylor, WR; White, NJ | 1 |
| Clardy, J; Daily, JP; Demas, A; Lakshmanan, V; LeRoux, M; Mboup, S; Ndiaye, D; Ndir, O; Patel, V; Wirth, DF | 1 |
| Oguonu, T; Okafor, HU; Shu, EN | 1 |
| Chevalley, S; Coste, A; Lopez, A; Pipy, B; Valentin, A | 1 |
| Dara, P; Deng, C; Jian, H; Li, G; Ou, F; Seila, S; Socheat, D; Sokunthea, S; Song, J; Tan, B | 1 |
| Bousema, T; Daou, M; Drakeley, C; Kavishe, R; Koenderink, JB; Luty, AJ; Sauerwein, RW; Shekalaghe, SA; ter Braak, R; van den Bijllaardt, W; van den Bosch, S; Whitty, CJ | 1 |
| Day, NP; Dondorp, AM; Nguon, C; Socheat, D; von Seidlein, L; White, L; Yeung, S | 1 |
| Anderson, TJ; Chotivanich, K; Das, D; Day, NP; Dondorp, AM; Imwong, M; Nair, S; Nkhoma, S; Socheat, D; White, NJ; Williams, JT; Yi, P | 1 |
| Chavchich, M; Chen, N; Cheng, Q; Gerena, L; Kyle, DE; Peters, J | 1 |
| Kachur, SP; MacArthur, JR; Slutsker, L | 1 |
| Anderson, TJ; Barends, M; Jaidee, A; Nair, S; Nosten, F; Price, RN; Sudimack, D; Williams, JT | 1 |
| Bustamante, LY; Woodrow, CJ | 1 |
| Angus, BJ; Anstey, NM; Douglas, NM; Nosten, F; Price, RN | 1 |
| Badiane, A; Baril, L; Faye, J; Ly, AB; Michel, R; Perry, R; Rogier, C; Sokhna, C; Tall, A; Touré, A; Trape, JF | 1 |
| Biggs, BA; Casey, GJ; Cowman, AF; Hung, NM; Phuc, BQ; Thanh, NV; Tien, NT; Toan, TQ | 1 |
| Chrubasik, C; Jacobson, RL | 1 |
| Alvarez, G; Blair, S; Piñeros, JG; Ríos, A; Tobón, A | 1 |
| Galea, S; Kruk, ME; Macauley, R; Rockers, PC; Saydee, G; Varpilah, ST; Williams, EH | 1 |
| Alvarez, M; Benoit-Vical, F; Berry, A; Iriart, X; Magnaval, JF; Marchou, B; Menard, S; Naneix-Laroche, V; Soh, PN; Witkowski, B | 1 |
| Basáñez, MG; Bousema, T; Churcher, TS; Drakeley, CJ; Ferguson, NM; Ghani, AC; Griffin, JT; Hinsley, W; Hollingsworth, TD; Okell, LC; White, M | 1 |
| Ashley, E; Aung, PP; Imwong, M; Kyaw, MK; Lee, SJ; Myint, NZ; Naing, AL; Nyo, MY; Oo, AP; Phe, O; Smithuis, F; White, NJ; Win, T | 1 |
| Harris, JC; Yeka, A | 1 |
| Adeyi, O; Atun, R | 1 |
| Ladhani, S; Shingadia, D | 1 |
| Bethell, D; Chan Thap, L; Fukuda, MM; Noedl, H; Rutvisuttinunt, W; Schaecher, K; Se, Y; Smith, B; Socheat, D; Sriwichai, S; Surasri, S; Teja-Isavadharm, P | 1 |
| Setiawan, B | 1 |
| Zarocostas, J | 2 |
| Diakite, S; Dicko, A; Djimde, A; Doumbo, O; Guindo, A; Kone, AK; Kurantsin-Mills, J; Sagara, I; Thera, MA; Walcourt, A | 1 |
| A-Elgayoum, SM; El-Rayah, EA; Giha, HA | 1 |
| Daniel-Ribeiro, CT; de Carvalho, LJ; de Oliveira, NK; de Souza, JM; Ferreira-da-Cruz, Mde F; Gama, BE; Melo, YF; Rosenthal, PJ; Santos, F | 1 |
| White, NJ | 4 |
| Bharti, PK; Chand, G; Dash, AP; Mehra, RK; Sharma, RK; Shukla, MK; Shukla, MM; Singh, MP; Singh, N | 1 |
| Hess, K; Tren, R | 1 |
| Cheng, Q; Codd, A; Gatton, ML; Kyle, DE; Teuscher, F | 1 |
| Held, J; Jansen, FH; Kremsner, PG; Mordmüller, B; Soomro, SA | 1 |
| Adegoke, SA; Adeyemi, LA; Olatunya, OS; Oyelami, OA | 1 |
| Adhikari, M; Alifrangis, M; Bygbjerg, IC; Kapel, CM; Ranjitkar, S; Schousboe, ML; Thomsen, TT | 1 |
| Eisele, TP; Steketee, RW; Thwing, J | 1 |
| Hayatsu, H; Higaki, K; Hiramoto, A; Hiramoto, K; Hiraoka, O; Kawai, S; Kim, HS; Komich, Y; Masuyama, A; Matsumoto, M; Morita, M; Nakase, Y; Nojima, M; Sato, A; Tanigawa, N; Wataya, Y | 1 |
| Bera, DK; Biswas, A; Das, M; Das, S; Guha, SK; Kundu, PK; Maji, AK; Mullick, S; Ray, K; Roy, D; Saha, P; Sengupta, S | 1 |
| Björkman, A; Ferreira, PE; Gil, JP; Jörnhagen, L; Kone, A; Malmberg, M; Nosten, F; Petzold, M; Schmidt, BA; Veiga, MI | 1 |
| Lynch, C; Roper, C | 1 |
| Abu-Bakar, N; Bottova, I; Crespo-Ortiz, MP; Kenny, S; Klonis, N; Rosenthal, PJ; Tilley, L | 1 |
| Bertaux, L; Delaunay, P; Marty, P; Pomares, C; Pradines, B | 1 |
| Basra, A; Bélard, S; Kurth, F; Ramharter, M | 1 |
| Chen, N; Cheng, Q; Gatton, ML; Kyle, DE; Teuscher, F | 1 |
| Fidock, DA; Henrich, PP; O'Brien, C; Passi, N | 1 |
| Kyle, DE; Mutka, T; Patel, J; Sparks, K; Tucker, MS | 1 |
| Alifrangis, M; Bygbjerg, IC; Ishengoma, DS; Lemnge, MM; Lusingu, JP; Mmbando, BP; Theander, TG; Thomsen, TT; Vestergaard, LS | 1 |
| Abossolo, BP; Adegnika, AA; Agnandji, ST; Auer-Hackenberg, L; Basra, A; Fernandes, JF; González, R; Issifou, S; Kizito, G; Kurth, F; Lell, B; Mayengue, PI; Mombo-Ngoma, G; Ramharter, M; Soulanoudjingar, SS | 1 |
| Arango, EM; Carmona-Fonseca, J; Upegui, YA | 1 |
| Gbotosho, GO; Happi, CT; Okuboyejo, TM; Sowunmi, A | 1 |
| Chanthongthip, O; Hongvanthong, B; Imwong, M; Khanthavong, M; Lee, SJ; Mayxay, M; Newton, PN; Phompida, S; Pongvongsa, T; Ringwald, P; Soonthornsata, B; Stepniewska, K; White, NJ | 1 |
| Kaale, EA; Mori, AT | 1 |
| Amor, A; Baquero, M; Benito, A; Berzosa, P; Fernández-Martínez, A; Toro, C | 1 |
| Kattenberg, JH; Mens, PF; Schallig, HD; Tahita, CM; Tinto, H; Traoré-Coulibaly, M; Versteeg, IA | 1 |
| Jung, C; Klein, EY; Levin, SA; Lewis, IA; Llinás, M | 1 |
| Al Saai, S; Anderson, TJ; Ashley, E; Cheeseman, IH; Dondorp, AM; Ferdig, MT; Imwong, M; Lwin, KM; Mayxay, M; McGready, R; Miller, BA; Moo, CL; Nair, S; Newton, PN; Nkhoma, S; Nosten, F; Phyo, AP; Stepniewska, K; Tan, A; Tan, JC; White, NJ; Yi, P | 1 |
| Awono-Ambene, P; Basco, LK; Benoit-Vical, F; Berry, A; Iriart, X; Lemen, B; Magnaval, JF; Mayengue, PI; Menard, S; Morlais, I; Sayang, C; Tahar, R | 1 |
| Abdulla, SM; Bloland, PB; Elling, BF; Genton, B; Goodman, CA; Gutman, JR; Kabanywanyi, AM; Kachur, SP; Kahigwa, E; Khatib, RA; Lyimo, T; MacArthur, JR; Mills, A; Mshinda, H; Mwita, A; Njau, JD; Roberts, JM; Skarbinski, J; Smith, EE; Somi, MF; Tanner, M | 1 |
| Duffull, SB; Jamsen, KM; Lindegardh, N; Simpson, JA; Tarning, J; White, NJ | 1 |
| Dara, P; Day, NP; Dondorp, AM; Li, G; Maude, RJ; Nguon, C; Saroth, P; Socheat, D; Song, J; White, LJ; White, NJ; Yeung, S | 1 |
| Delacollette, C; Kaewkungwal, J; Khamsiriwatchara, A; Lawpoolsri, S; Potithavoranan, T; Sangvichean, A; Satimai, W; Sawang, S; Singhasivanon, P; Sudathip, P; Vijakadge, S | 1 |
| Albertini, A; Bell, D; Bennett, A; Chisha, Z; Eisele, TP; Hamainza, B; Incardona, S; Keating, J; Miller, JM; Moonga, H; Yukich, JO | 1 |
| Breman, JG; Dondorp, AM; Duong, S; Fairhurst, RM; Hallett, R; Nayyar, GML; Plowe, CV; Ringwald, P; Vennerstrom, JL; Wellems, TE | 1 |
| Holen, Ø | 1 |
| Avery, MA; Helal, MA | 1 |
| Delacollette, C; Kaewkungwal, J; Khamsiriwatchara, A; Lawpoolsri, S; Potithavoranan, T; Sangvichean, A; Satimai, W; Sawang, S; Singhasivanon, P; Sudathip, P; Vijaykadga, S | 1 |
| Breman, JG | 1 |
| Amaratunga, C; Anderson, JM; Anderson, TJ; Dondorp, AM; Duong, S; Fairhurst, RM; Fay, MP; Jiang, H; Lim, P; Lindegardh, N; Mao, S; Mu, J; Phelps, ES; Song, J; Sreng, S; Stepniewska, K; Su, XZ; Suon, S; White, NJ; Zhou, C | 1 |
| Ayong, L; Dossin, Fde M; Freitas-Junior, LH; Genovesio, A; Hansen, MA; Ku, MJ | 1 |
| Adhin, MR; Labadie-Bracho, M; Vreden, SG | 1 |
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| Kusriastuti, R; Surya, A | 1 |
| D'Alessandro, U; Donegan, S; Garner, P; Smith, CT; Williamson, P | 1 |
| Ariey, F; Bjorge, S; Chea, N; Christophel, EM; Duong, S; Habib, N; Hoyer, S; Kheng, S; Khim, N; Kim, S; Mellor, S; Menard, D; Newman, RD; Nguon, S; Ros, S; Sophal, U; Sum, S; Thompson, MM; Thomson, A; Top, S; Witkowski, B; Yeang, C; Yeung, S; Yok, S | 1 |
| D'Alessandro, U; Guerin, PJ; Juma, E; Karema, C; Logedi, J; Mbacham, WF; Mulenga, M; Nyandigisi, A; Ogutu, B; Roper, C; Snow, RW; Talisuna, AO | 1 |
| David, B; Meek, S; Newman, RD; Tulloch, J | 1 |
| Afsharpad, M; Djadid, ND; Hemati, S; Pirahmadi, S; Raeisi, A; Zakeri, S | 1 |
| Dondorp, AM | 1 |
| Chotivanich, K; Das, D; Day, NP; Dondorp, AM; Hanpithakpong, W; Imwong, M; Lee, SJ; Lindegardh, N; Lwin, KM; Menard, D; Nguon, C; Nosten, F; Phyo, AP; Ringwald, P; Silamut, K; Socheat, D; Stepniewska, K; Tarning, J; Tripura, R; White, NJ; Yi, P | 1 |
| Amor, A; Benito, A; Berzosa, P; Charle, P; Cravo, P; Fernández-Martínez, A; Mula, P; Ncogo, P | 1 |
| Casimiro, PN; Ibara, JR; Ibara-Okabande, R; Koukouikila-Koussounda, F; Malonga, V; Ndounga, M; Ntoumi, F; Sidibe, A; Vouvoungui, J | 1 |
| Luzzatto, L; Qi, G; Qiao, LG; White, NJ | 1 |
| Afsharpad, M; Djadid, ND; Pirahmadi, S; Zakeri, S | 1 |
| Balbiano, R; Calleri, G; Caramello, P | 1 |
| Das Sutar, SK; Dhangadamajhi, G; Kar, SK; Ranjit, M | 1 |
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| Alin, H; Ashton, M; Bergqvist, Y; Karlsson, MO; Svensson, US | 1 |
| Bray, PG; Hastings, IM; Ward, SA | 1 |
| Gan, EK; Ho, SS; Nagappan, S; Shahul, WS; Toh, WT; Wong, JW; Yuen, KH | 1 |
| Biggs, B; Cowman, AF; Duraisingh, M; Hipgrave, D; Ngo, T; Reed, M | 1 |
| Abdin, MZ; Israr, M; Jain, SK; Rehman, RU | 1 |
| Dagan, A; Flescher, E; Gatt, S; Gold, D; Pankova-Kholmyansky, I; Skutelsky, E; Zaslavsky, Z | 1 |
| Albrecht, R; Johann-Liang, R | 1 |
| Birku, Y; Björkman, A; Mekonnen, E; Wolday, D | 1 |
| Benoit-Vical, F; Camus, D; Capron, M; Delhaes, L; Meunier, B | 1 |
| Avery, MA; Bandyopadhyaya, AK; Desai, PV; Furtado, MM; Muraleedharan, KM; Tekwani, BL | 1 |
| Duffy, PE; Mutabingwa, TK | 1 |
| Attaran, A; Barnes, KI; Curtis, C; d'Alessandro, U; Fanello, CI; Galinski, MR; Kokwaro, G; Looareesuwan, S; Makanga, M; Mutabingwa, TK; Talisuna, A; Trape, JF; Watkins, WM | 1 |
| Cao, WC; Ding, DB; Li, GF; Shan, CQ; Shi, YL; Wang, JY; Wu, BA; Zhang, M | 1 |
| Barman, K; Dev, V; Phookan, S | 1 |
| Singhal, T | 1 |
| Brewer, TG; Kyle, DE; Peggins, JO; Teja-Isavadharm, P; Webster, HK; White, NJ | 1 |
| Carucci, DJ; Cooper, RA | 1 |
| Brown, ML; Geyer, JA; Terrell, JC; Trotta, RF | 1 |
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| Beg, MA; Khan, MA; Razi, ST; Smego, RA | 1 |
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| Barnes, KI; McIntyre, D; Muheki, C | 1 |
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| Chandrasekhara, KV; Rao, VS; Sriram, D; Yogeeswari, P | 1 |
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| Bhattarai, A; Björkman, A | 1 |
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| Kollaritsch, H; Rojanawatsirivet, C; Sirichainsinthop, J; Thriemer, K; Wernsdorfer, G; Wernsdorfer, WH | 1 |
| Beckermann, B; Chan, HW; Cheung, MK; Croft, SL; Edstein, MD; Fugmann, B; Gerisch, M; Haynes, RK; Heilmann, HD; Kotecka, B; Kyle, DE; Lam, WL; Peters, W; Radtke, M; Rattray, L; Rieckmann, K; Robinson, BL; Römer, A; Schmeer, K; Schmuck, G; Steinke, W; Stetter, J; Stewart, L; Vivas, L; Wollborn, U; Wong, HN | 1 |
| Duangdee, C; Faithong, S; Haoharn, O; Krudsood, S; Leowattana, W; Looareesuwan, S; Phophak, N; Piyaphanee, W; Silachamroon, U; Tangpukdee, N; Thanachartwet, W; Wilairatana, P | 1 |
| Bar-Zeev, N; White, N | 1 |
| Chang, MC; Eachus, RA; Fisher, KJ; Ham, TS; Ho, KA; Keasling, JD; Kirby, J; Ndungu, JM; Newman, KL; Ouellet, M; Paradise, EM; Ro, DK; Sarpong, R; Shiba, Y; Withers, ST | 1 |
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| de Radiguès, X; Diallo, KI; Diallo, M; Djimdé, A; Doumbo, O; Guthmann, JP; Maiga, H; Ngwakum, PA; Sacko, M | 1 |
| Ashley, E; Aye, KZ; Barends, M; Htet, L; Kyaw, MK; Lindegardh, N; Lwin, S; Phe, O; Singtoroj, T; Smithuis, F; Stepniewska, K; White, NJ | 1 |
| Fidock, DA; Krishna, S; Sidhu, AB; Uhlemann, AC; Valderramos, JC; Valderramos, SG | 1 |
| Ahmed, ES; Elamin, SB; Elhassan, AH; Elmardi, KA; Malik, EM; Mannan, AA; Mohamed, TA; Mowien, RM | 1 |
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| Bustamante, LY; Krishna, S; Matile, H; Uhlemann, AC; Wittlin, S | 1 |
| Benoit-Vical, F; Berry, A; Lelièvre, J | 1 |
| Andrianina, NN; Jahevitra, M; Ménard, D; Ramiandrasoa, Z; Randriamanantena, A; Rasoarilalao, N; Ratsimbasoa, A; Raveloson, A; Tuseo, L | 1 |
| De-Eknamkul, W; Matangkasombut, O; Putalun, W; Shoyama, Y; Tanaka, H | 1 |
| Bouwmeester, HJ; Elzinga, S; Lommen, WJ; Verstappen, FW | 1 |
| Enserink, M | 1 |
| Abbas, AK; Abdulla, S; Al-Mafazy, AW; Ali, AS; Bhattarai, A; Björkman, A; Gerstenmaier, JF; Kachur, SP; Kaneko, A; Khatib, R; Mårtensson, A; Molteni, F; Montgomery, SM; Ramsan, M; Rotllant, G | 1 |
| Bosman, A; Mendis, KN | 1 |
| Dama, S; Djimdé, A; Doumbo, O; Fofana, B; Hubert, V; Kaddouri, H; Kodio, A; Koné, A; Le Bras, J; Maiga, H; Sangaré, CP; Sidibe, B; Tekete, M; Yattara, O | 1 |
| Ekland, EH; Fidock, DA | 1 |
| Mills, A; Socheat, D; Van Damme, W; White, NJ; Yeung, S | 1 |
| Burgmann, H; Graninger, W; Hollenstein, U; Looareesuwan, S; Thalhammer, F; Wenisch, C | 1 |
| Nosten, F; Price, RN | 1 |
| Chen, PQ; Fu, LC; Fu, YX; Guo, XB; He, KR; Li, GQ; Song, YZ | 1 |
| Ager, A; Andersen, SL; Berman, J; Ellis, W; Kuschner, R; McGreevy, P; Ohrt, C; Rossan, R; Schuster, BG; Wesche, D | 1 |
| Chen, PQ; Guo, XB; Li, GQ | 1 |
| Beekman, AC; Lugt, CB; Pras, N; van Uden, W; Wallaart, TE; Woerdenbag, HJ | 1 |
| Arnold, K | 1 |
| Fu, LC; Guo, XB; Jian, HX; Li, GQ; Wang, XH | 1 |
| Looareesuwan, S | 1 |
| Hien, TT | 1 |
| Hopperus Buma, AP; Kager, PA; Leentvaar-Kuijpers, A; Tendeloo, CH; van Gool, T; van Thiel, PP | 1 |
| Ager, AL; Oh, CH; Posner, GH; Rossan, RN; Webster, HK | 1 |
| Hong, YL; Meshnick, SR; Yang, YZ | 1 |
| Dao, BH; Le, NB; Mai, VS; Meshnick, SR; Nguyen, DS; Nguyen, PD; Nguyen, VH | 1 |
| Kager, PA | 1 |
| Kamchonwongpaisan, S; Kuypers, F; Lima, V; Meshnick, SR; Yang, YZ; Yuthavong, Y | 1 |
| Alin, MH; Ashton, M; Bjorkman, A; Bwijo, BA; Kihamia, CM; Mtey, GJ; Premji, Z | 1 |
| Ambroise-Thomas, P | 3 |
| Chongsuphajaisiddhi, T; Luxemburger, C; Nosten, F; Paiphun, L; Price, RN; ter Kuile, FO; White, NJ | 1 |
| Danis, M | 1 |
| Chaudhury, RR | 1 |
| Alin, MH; Ashton, M; Björkman, A; Kihamia, CM; Mtey, GJ | 1 |
| Kamchonwongpaisan, S; Meshnick, SR; Taylor, TE | 1 |
| Davis, TM; Johnston, WA; Manning, LS; Skinner, TS | 1 |
| Burgmann, H; Graninger, W; Looareesuwan, S; Vanijanonta, S; Viravan, C; Vorbach, H; Zedwitz-Liebenstein, K | 1 |
| Cumming, JN; Ploypradith, P; Posner, GH | 1 |
| Anh, TK; Bich, NN; De Vries, PJ; Eggelte, TA; Hung, LN; Kager, PA; Phong, TH; Van Thien, H | 1 |
| Dao, DD; De Vries, PJ; Kager, PA; Le Nguyen, B; Nguyen, XK; Pham, TY; Tran, KD; Van Boxtel, CJ | 1 |
| Aust-Kettis, A; Björkman, A; Ekvall, H | 1 |
| Liu, Y | 1 |
| Davis, TM; Edwards, GO; McCarthy, JS | 1 |
| Davis, TM; Le, TA; Nguyen, VP; Tran, QB; Trinh, KA | 1 |
| Gera, R; Khalil, A | 1 |
| Burgmann, H; El Menyawi, I; Knapp, S; Looareesuwan, S; Stoiser, B; Thalhammer, F | 1 |
| Ashton, M; Cong, LD; Hai, TN; Huong, NV; Jonsson, EN; Karlsson, MO; Sidhu, JS; Sy, ND | 1 |
| Kremsner, PG; Philipps, J; Radloff, PD; Wernsdorfer, W | 1 |
| Høgh, B | 1 |
| Newton, P; White, N | 1 |
| Li, Y; Wu, YL | 1 |
| Meshnick, SR | 1 |
| Le Bras, J | 1 |
| Kyle, DE; Leo, K; Li, Q; Teja-Isavadharm, P | 1 |
| Hien, TT; Nosten, F; White, NJ | 1 |
| McIntosh, HM; Olliaro, P | 4 |
| Looareesuwan, S; Wilairatana, P | 2 |
| White, N | 1 |
| Anderson, RM; Danis, M; Greenwood, BM; Hien, TT; Kokwaro, G; Looareesuwan, S; Marsh, K; Molyneux, ME; Newbold, CI; Nosten, F; Olliaro, P; Ouma, J; Ruebush, TK; Snow, RW; Taylor, TE; Watkins, WM; White, NJ | 1 |
| Chongsuphajaisiddhi, T; Luxemburger, C; Nosten, F; Phaipun, L; Price, R; Simpson, JA; ter Kuile, F; van Vugt, M; White, NJ | 1 |
| Akompong, T; Ghori, N; Haldar, K; VanWye, J | 1 |
| Birku, Y; Bjorkman, A; Makonnen, E | 1 |
| Duraisingh, MT; Jones, P; Pinder, M; Sambou, I; von Seidlein, L; Warhurst, DC | 2 |
| Mishra, SK; Mohanty, S | 1 |
| de Vries, PJ; Kager, PA | 1 |
| Burgmann, H; Chullawichit, S; Daxböck, F; El-Menyawi, I; Graninger, W; Looareesuwan, S; Stoiser, B; Thalhammer, F | 1 |
| Brittenham, GM; Gordeuk, VR; Hutagalung, R; Looareesuwan, S; Wilairatana, P | 1 |
| Anh, TK; Bich, NN; de Vries, PJ; Heisterkamp, SH; Hung, LN; Kager, PA; Van Thien, H | 1 |
| Karbwang, J; Na-Bangchang, K; Songthammawat, D; Tan-ariya, P; Ubalee, R | 1 |
| Bodeker, G | 1 |
| Kain, KC; Looareesuwan, S; Mirabelli-Primdahl, L; Ohrt, C; Walsh, D; Wilairatana, P | 1 |
| Benoit-Vical, F; Meunier, B; Robert, A | 1 |
| Agarwal, AK; Gupta, B; Tripathi, BK | 1 |
| Chantharaksri, U; Dangdoungjai, J; Looareesuiwan, S; Pipitaporn, B; Sibmooh, N; Udomsangpetch, R; Wilairatana, P | 1 |
| Ashton, M; Gordi, T; Hai, TN; Hoai, NM; Thyberg, M | 1 |
| Das, B; Jena, RK; Parida, P; Swain, KP | 1 |
| Haynes, RK; Meunier, B; Olliaro, PL; Yuthavong, Y | 1 |
| Etchegorry, MG; Galinski, M; Matthys, F; Nosten, F; White, NJ | 1 |
| Meshnick, SR; Posner, GP | 1 |
| Looareesuwan, S; Silachamroon, U; Treeprasertsuk, S; Vannphan, S; Viriyavejakul, P; Wilairatana, P | 1 |
| Blum, PG; Stephens, D | 1 |
| Winstanley, P | 1 |
| Cho, T; Keo, NK; Looareesuwan, S; McGready, R; Nosten, F; Thwai, KL; Villegas, L; White, NJ | 1 |
| Binh, TQ; de Vries, PJ; Giao, PT; Kager, PA; Long, HP; Van Nam, N; Van Thang, N | 1 |
| Kollaritsch, H; Krudsood, S; Looareesuwan, S; Noedl, H; Viriyavejakul, P; Wernsdorfer, WH; Wiedermann, G; Wilairatana, P | 1 |
| Lalloo, D; Trevett, A | 1 |
126 review(s) available for artemisinin and Malaria, Falciparum
| Article | Year |
|---|---|
New insights into the spread of resistance to artemisinin and its analogues.
Topics: Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria, Falciparum; Protozoan Proteins | 2021 |
Drug-induced hypersensitivity to artemisinin-based therapies for malaria.
Topics: Antimalarials; Artemisinins; Drug Therapy, Combination; Humans; Hypersensitivity; Malaria; Malaria, Falciparum; Plasmodium falciparum | 2022 |
Plasmodium falciparum resistance to artemisinin-based combination therapies.
Topics: Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria, Falciparum; Plasmodium falciparum; Protozoan Proteins | 2022 |
Pregnancy outcomes after first-trimester treatment with artemisinin derivatives versus non-artemisinin antimalarials: a systematic review and individual patient data meta-analysis.
Topics: Abortion, Spontaneous; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Drug Combinations; Ethanolamines; Female; Humans; Malaria; Malaria, Falciparum; Pregnancy; Pregnancy Outcome; Pregnancy Trimester, First; Prospective Studies; Quinine; Stillbirth | 2023 |
Bangladesh in the era of malaria elimination.
Topics: Antimalarials; Bangladesh; Drug Resistance; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum | 2023 |
The many paths to artemisinin resistance in Plasmodium falciparum.
Topics: Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria, Falciparum; Mutation; Plasmodium falciparum; Protozoan Proteins | 2023 |
The effect and control of malaria in pregnancy and lactating women in the Asia-Pacific region.
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Asia; Female; Humans; Lactation; Malaria; Malaria, Falciparum; Pregnancy | 2023 |
Exploring the feasibility of introducing triple artemisinin-based combination therapy in the malaria treatment policy in Vietnam.
Topics: Antimalarials; Artemisinins; Drug Therapy, Combination; Feasibility Studies; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum; Policy; Vietnam | 2023 |
Systematic review of artesunate pharmacokinetics: Implication for treatment of resistant malaria.
Topics: Administration, Intravenous; Administration, Oral; Antimalarials; Artemisinins; Artesunate; Asia, Southeastern; Drug Monitoring; Drug Resistance; Humans; Malaria; Malaria, Falciparum | 2019 |
Importance of kelch 13 C580Y mutation in the studies of artemisinin resistance in Plasmodium falciparum in Greater Mekong Subregion.
Topics: Africa; Alleles; Artemisinins; Cambodia; Drug Resistance; Humans; India; Malaria, Falciparum; Mutation; Plasmodium falciparum; Prevalence; Thailand; Vietnam | 2020 |
Profiles of Kelch mutations in Plasmodium falciparum across South Asia and their implications for tracking drug resistance.
Topics: Antimalarials; Artemisinins; Asia; Drug Resistance; Drug Therapy, Combination; Endemic Diseases; India; Kelch Repeat; Malaria, Falciparum; Mutation; Plasmodium falciparum | 2019 |
Enhancing the antimalarial activity of artesunate.
Topics: Antimalarials; Artemisinins; Artesunate; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Plasmodium falciparum | 2020 |
Molecular Mechanisms of Drug Resistance in
Topics: Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Humans; Malaria, Falciparum; Membrane Transport Proteins; Mutation; Plasmodium falciparum; Protozoan Proteins; Quinolines | 2020 |
Spatial and molecular mapping of Pfkelch13 gene polymorphism in Africa in the era of emerging Plasmodium falciparum resistance to artemisinin: a systematic review.
Topics: Africa; Antimalarials; Artemisinins; DNA, Protozoan; Drug Resistance; Genes, Protozoan; Humans; Malaria, Falciparum; Mutation; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins | 2021 |
Variation in Calculating and Reporting Antimalarial Efficacy against Plasmodium falciparum in Sub-Saharan Africa: A Systematic Review of Published Reports.
Topics: Africa South of the Sahara; Analysis of Variance; Antimalarials; Artemisinins; Data Interpretation, Statistical; Drug Resistance; Guideline Adherence; Guidelines as Topic; Humans; Kaplan-Meier Estimate; Malaria, Falciparum; Plasmodium falciparum; Recurrence; Treatment Outcome | 2021 |
[Plasmodium falciparum resistance to artemisinin-based combination therapies (ACTs): Fears of widespread drug resistance].
Topics: Antimalarials; Artemisinins; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Plasmodium falciparum | 2016 |
Animal Embryotoxicity Studies of Key Non-Artemisinin Antimalarials and Use in Women in the First Trimester.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Drug Combinations; Female; Humans; Malaria; Malaria, Falciparum; Naphthyridines; Pregnancy; Pregnancy Trimester, First; Pyrimethamine; Quinine; Quinolines; Rabbits; Rats; Sulfadoxine; Teratogens | 2017 |
Protein Degradation Systems as Antimalarial Therapeutic Targets.
Topics: Antimalarials; Artemisinins; Drug Resistance; Malaria, Falciparum; Plasmodium falciparum; Proteasome Endopeptidase Complex; Proteolysis | 2017 |
Antimalarial drug resistance: linking Plasmodium falciparum parasite biology to the clinic.
Topics: Antimalarials; Artemisinins; Asia, Southeastern; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Malaria, Falciparum; Plasmodium falciparum | 2017 |
Pharmacokinetic considerations for use of artemisinin-based combination therapies against falciparum malaria in different ethnic populations.
Topics: Antimalarials; Area Under Curve; Artemisinins; Drug Therapy, Combination; Ethnicity; Half-Life; Humans; Malaria, Falciparum; Racial Groups | 2017 |
Methodology of assessment and reporting of safety in anti-malarial treatment efficacy studies of uncomplicated falciparum malaria in pregnancy: a systematic literature review.
Topics: Abortion, Spontaneous; Adverse Drug Reaction Reporting Systems; Antimalarials; Artemisinins; Female; Humans; Infant, Newborn; Malaria, Falciparum; Pregnancy; Pregnancy Outcome; Quinine; Stillbirth; Treatment Outcome | 2017 |
Overview of the improvement of the ring-stage survival assay-a novel phenotypic assay for the detection of artemisinin-resistant
Topics: Antimalarials; Artemisinins; Biological Assay; Drug Resistance; Humans; Malaria, Falciparum; Plasmodium falciparum | 2017 |
Artemisinin Therapy for Malaria in Hemoglobinopathies: A Systematic Review.
Topics: Antimalarials; Artemisinins; Hemoglobinopathies; Humans; Malaria, Falciparum | 2018 |
Efficacy and safety of artemisinin-based combination therapy for uncomplicated Plasmodium falciparum malaria in Sudan: a systematic review and meta-analysis.
Topics: Antimalarials; Artemisinins; Drug Therapy, Combination; Humans; Malaria, Falciparum; Sudan | 2018 |
Association of mutations in the Plasmodium falciparum Kelch13 gene (Pf3D7_1343700) with parasite clearance rates after artemisinin-based treatments-a WWARN individual patient data meta-analysis.
Topics: Africa; Animals; Antimalarials; Artemisinins; Asia; Drug Resistance; Genes, Protozoan; Genotype; Humans; Kelch Repeat; Malaria, Falciparum; Mutation; Phenotype; Plasmodium falciparum | 2019 |
Antimalarial drug resistance in Africa: the calm before the storm?
Topics: Africa South of the Sahara; Antimalarials; Artemisinins; Child; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Incidence; Malaria, Falciparum; Plasmodium falciparum; Treatment Outcome | 2019 |
Antidogmatic approaches to artemisinin resistance: reappraisal as treatment failure with artemisinin combination therapy.
Topics: Animals; Antimalarials; Artemisinins; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Plasmodium falciparum; Treatment Failure | 2013 |
Chemotherapy and drug resistance status of malaria parasite in northeast India.
Topics: Animals; Anopheles; Antimalarials; Artemisinins; Chloroquine; Drug Resistance, Multiple; Drug Therapy, Combination; Humans; India; Malaria, Falciparum; Malaria, Vivax; Plasmodium falciparum; Plasmodium vivax; Quinine | 2013 |
Malaria.
Topics: Africa South of the Sahara; Amodiaquine; Animals; Anopheles; Antimalarials; Artemisinins; Artesunate; Asia, Southeastern; Chloroquine; Drug Administration Schedule; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Humans; Insecticide-Treated Bednets; Insecticides; Malaria; Malaria Vaccines; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Pregnancy; Pregnancy Complications, Infectious; Primary Prevention; Pyrimethamine; Quinine; Quinolines; Seasons; Sulfadoxine | 2014 |
Fighting drug-resistant Plasmodium falciparum: the challenge of artemisinin resistance.
Topics: Antimalarials; Artemisinins; Asia, Southeastern; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Parasitemia; Plasmodium falciparum | 2013 |
Modelling the time course of antimalarial parasite killing: a tour of animal and human models, translation and challenges.
Topics: Animals; Antimalarials; Artemisinins; Drug Dosage Calculations; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Models, Biological; Parasites; Time Factors; Translational Research, Biomedical | 2015 |
Blocking malaria transmission to Anopheles mosquitoes using artemisinin derivatives and primaquine: a systematic review and meta-analysis.
Topics: Animals; Anopheles; Antimalarials; Artemisinins; Humans; Malaria, Falciparum; Plasmodium falciparum; Primaquine | 2013 |
Artesunate plus pyronaridine for treating uncomplicated Plasmodium falciparum malaria.
Topics: Adult; Antimalarials; Artemisinins; Artesunate; Child; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Liver; Lumefantrine; Malaria, Falciparum; Mefloquine; Naphthyridines; Randomized Controlled Trials as Topic | 2014 |
A review of dihydroartemisinin as another gift from traditional Chinese medicine not only for malaria control but also for schistosomiasis control.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Drugs, Chinese Herbal; Female; Malaria, Falciparum; Mice; Praziquantel; Schistosomiasis japonica; Schistosomicides | 2014 |
Novel anti-malarial combinations and their toxicity.
Topics: Animals; Antimalarials; Artemisinins; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Malaria, Falciparum; Molecular Structure; Pharmacovigilance; Plasmodium falciparum | 2014 |
Neuroauditory toxicity of artemisinin combination therapies-have safety concerns been addressed?
Topics: Adult; Antimalarials; Artemisinins; Auditory Diseases, Central; Child, Preschool; Drug Administration Schedule; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Neurotoxicity Syndromes; Plasmodium falciparum | 2014 |
Primaquine or other 8-aminoquinoline for reducing P. falciparum transmission.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Combinations; Glucosephosphate Dehydrogenase Deficiency; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Primaquine; Pyrimethamine; Quinine; Randomized Controlled Trials as Topic; Sulfadoxine | 2014 |
A review of the effects of artemether-lumefantrine on gametocyte carriage and disease transmission.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Drug Combinations; Ethanolamines; Fluorenes; Humans; Malaria, Falciparum; Plasmodium falciparum; Trophozoites | 2014 |
Independent emergence of artemisinin resistance mutations among Plasmodium falciparum in Southeast Asia.
Topics: Antimalarials; Artemisinins; Asia, Southeastern; Drug Resistance; Genotype; Humans; Malaria, Falciparum; Mutation; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins | 2015 |
Strategic use of antimalarial drugs that block falciparum malaria parasite transmission to mosquitoes to achieve local malaria elimination.
Topics: Aminoquinolines; Animals; Antimalarials; Artemisinins; Culicidae; Disease Eradication; Drug Resistance; Humans; Insect Vectors; Malaria, Falciparum; Plasmodium falciparum | 2014 |
Drug resistance genomics of the antimalarial drug artemisinin.
Topics: Antimalarials; Artemisinins; Drug Resistance; Genomics; Humans; Malaria, Falciparum; Plasmodium falciparum | 2014 |
Falsified antimalarials: a minireview.
Topics: Adult; Africa South of the Sahara; Antimalarials; Artemisinins; Artesunate; Child, Preschool; Counterfeit Drugs; Fraud; Humans; Infant; Law Enforcement; Malaria, Falciparum; Plasmodium falciparum; Quality Control; Survival Analysis | 2015 |
Primaquine or other 8-aminoquinoline for reducing Plasmodium falciparum transmission.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Combinations; Glucosephosphate Dehydrogenase Deficiency; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Primaquine; Pyrimethamine; Quinine; Randomized Controlled Trials as Topic; Sulfadoxine | 2015 |
[Artemisinin resistance in Plasmodium falciparum: global status and basic research].
Topics: Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria, Falciparum; Plasmodium falciparum | 2014 |
Fighting fire with fire: mass antimalarial drug administrations in an era of antimalarial resistance.
Topics: Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Drug Therapy, Combination; History, 20th Century; History, 21st Century; Humans; Malaria, Falciparum; Plasmodium falciparum; Pyrimethamine; Sulfadoxine | 2015 |
Artemisinin-based combination therapy in the treatment of uncomplicated malaria: review of recent regulatory experience at the European Medicines Agency.
Topics: Antimalarials; Artemisinins; Drug and Narcotic Control; Drug Therapy, Combination; Europe; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum | 2015 |
Monitoring of efficacy and safety of artemisinin-based anti-malarials for treatment of uncomplicated malaria: a review of evidence of implementation of anti-malarial therapeutic efficacy trials in Tanzania.
Topics: Antimalarials; Artemisinins; Clinical Trials as Topic; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Humans; Malaria, Falciparum; Tanzania; Treatment Outcome | 2015 |
How genomics is contributing to the fight against artemisinin-resistant malaria parasites.
Topics: Africa; Animals; Antimalarials; Artemisinins; Asia, Southeastern; Drug Resistance; Genomics; Humans; Malaria, Falciparum; Plasmodium falciparum | 2015 |
Tailoring a Pediatric Formulation of Artemether-Lumefantrine for Treatment of Plasmodium falciparum Malaria.
Topics: Antimalarials; Artemether; Artemisinins; Chemistry, Pharmaceutical; Clinical Trials, Phase III as Topic; Drug Combinations; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Plasmodium falciparum; Randomized Controlled Trials as Topic; Tablets | 2015 |
The emerging threat of artemisinin resistance in malaria: focus on artemether-lumefantrine.
Topics: Africa South of the Sahara; Antimalarials; Artemether; Artemisinins; Asia; Drug Combinations; Drug Resistance; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Plasmodium falciparum | 2015 |
Understanding artemisinin-resistant malaria: what a difference a year makes.
Topics: Antimalarials; Artemisinins; Drug Resistance; Genes, Protozoan; Humans; Malaria, Falciparum; Plasmodium falciparum | 2015 |
Clinical determinants of early parasitological response to ACTs in African patients with uncomplicated falciparum malaria: a literature review and meta-analysis of individual patient data.
Topics: Africa; Africa South of the Sahara; Amodiaquine; Antimalarials; Artemisinins; Drug Combinations; Drug Therapy, Combination; Humans; Infant; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Prospective Studies; Quinolines | 2015 |
Baseline data of parasite clearance in patients with falciparum malaria treated with an artemisinin derivative: an individual patient data meta-analysis.
Topics: Adolescent; Adult; Aged; Animals; Antimalarials; Artemisinins; Blood; Child; Child, Preschool; Clinical Trials as Topic; Drug Resistance; Female; Humans; Infant; Malaria, Falciparum; Male; Middle Aged; Parasitemia; Plasmodium falciparum; Young Adult | 2015 |
Gametocyte carriage in uncomplicated Plasmodium falciparum malaria following treatment with artemisinin combination therapy: a systematic review and meta-analysis of individual patient data.
Topics: Amodiaquine; Antimalarials; Artemisinins; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Host-Parasite Interactions; Humans; Logistic Models; Malaria, Falciparum; Male; Microscopy; Middle Aged; Plasmodium falciparum; Proportional Hazards Models; Recurrence | 2016 |
Artemisinin-Resistant Plasmodium falciparum Malaria.
Topics: Animals; Anopheles; Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria, Falciparum; Molecular Epidemiology; Plasmodium falciparum | 2016 |
Recent advances in malaria genomics and epigenomics.
Topics: Animals; Antimalarials; Artemisinins; Biological Evolution; Drug Resistance; Epigenesis, Genetic; Genome, Protozoan; Genomics; Host-Parasite Interactions; Humans; Kelch Repeat; Malaria, Falciparum; Mosquito Vectors; Plasmodium falciparum; Protozoan Proteins; Reverse Genetics | 2016 |
Prevention and control of malaria in pregnancy - new threats, new opportunities?
Topics: Adult; Animals; Antimalarials; Artemisinins; Culicidae; Drug Combinations; Drug Resistance; Female; Humans; Insecticide-Treated Bednets; Malaria, Falciparum; Malaria, Vivax; Pregnancy; Pregnancy Complications, Parasitic; Primary Prevention; Pyrimethamine; Quinolines; Sulfadoxine | 2017 |
Risk of drug resistance in Plasmodium falciparum malaria therapy-a systematic review and meta-analysis.
Topics: Amodiaquine; Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinolines; Risk; Sulfadoxine | 2017 |
How to Contain Artemisinin- and Multidrug-Resistant Falciparum Malaria.
Topics: Antimalarials; Artemisinins; Cambodia; Disease Eradication; Drug Resistance; Humans; Malaria, Falciparum; Plasmodium falciparum | 2017 |
Antimalarial Drug Resistance: A Threat to Malaria Elimination.
Topics: Antigens, Bacterial; Antigens, Surface; Antimalarials; Artemisinins; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Malaria, Vivax; Plasmodium | 2017 |
Reduction of transmission from malaria patients by artemisinin combination therapies: a pooled analysis of six randomized trials.
Topics: Animals; Antimalarials; Artemisinins; Child; Child, Preschool; Culicidae; Drug Therapy, Combination; Gambia; Humans; Kenya; Malaria, Falciparum; Multivariate Analysis; Parasitemia; Plasmodium falciparum; Randomized Controlled Trials as Topic; Regression Analysis; Treatment Failure | 2008 |
Lessons learnt from the six decades of chloroquine use (1945-2005) to control malaria in Madagascar.
Topics: Adolescent; Animals; Antimalarials; Artemisinins; Child; Chloroquine; Disease Outbreaks; Drug Resistance; Drug Therapy, Combination; Evidence-Based Practice; Health Policy; Humans; Madagascar; Malaria, Falciparum; Membrane Transport Proteins; Plasmodium falciparum; Prevalence; Protozoan Proteins | 2009 |
Quinine monotherapy for treating uncomplicated malaria in the era of artemisinin-based combination therapy: an appropriate public health policy?
Topics: Africa; Animals; Antimalarials; Artemisinins; Drug Resistance; Drug Therapy, Combination; Health Policy; Humans; Malaria, Falciparum; Plasmodium falciparum; Quinine | 2009 |
Artemisinin-based combination therapy for treating uncomplicated malaria.
Topics: Antimalarials; Artemisinins; Artesunate; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Parasitemia; Pyrimethamine; Quinolines; Randomized Controlled Trials as Topic; Sulfadoxine | 2009 |
Detection of artemisinin-resistant Plasmodium falciparum in malarial infection: a brief review of methods.
Topics: Anti-Infective Agents; Artemisinins; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum; Point Mutation | 2010 |
Artemisinin resistance: current status and scenarios for containment.
Topics: Antimalarials; Artemisinins; Cambodia; Disease Outbreaks; Drug Resistance; Malaria, Falciparum; Plasmodium falciparum; Thailand | 2010 |
Artemisinin combination therapy for vivax malaria.
Topics: Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Malaria, Vivax; Plasmodium falciparum; Plasmodium vivax | 2010 |
Treating uncomplicated malaria in children: comparing artemisinin-based combination therapies.
Topics: Africa South of the Sahara; Antimalarials; Artemisinins; Asia, Southeastern; Child; Drug Combinations; Health Services Accessibility; Humans; Malaria, Falciparum; Patient Acceptance of Health Care | 2010 |
Protective efficacy of malaria case management and intermittent preventive treatment for preventing malaria mortality in children: a systematic review for the Lives Saved Tool.
Topics: Africa South of the Sahara; Antimalarials; Artemisinins; Case Management; Child; Child Mortality; Drug Therapy, Combination; Humans; Malaria, Falciparum; Quinine; Treatment Outcome | 2011 |
Pyronaridine-artesunate combination therapy for the treatment of malaria.
Topics: Antimalarials; Artemisinins; Drug Combinations; Humans; Malaria, Falciparum; Malaria, Vivax; Naphthyridines | 2011 |
Recent clinical and molecular insights into emerging artemisinin resistance in Plasmodium falciparum.
Topics: Antimalarials; Artemisinins; Asia, Southeastern; Drug Resistance; Humans; Malaria, Falciparum; Plasmodium falciparum | 2011 |
Artemisinin-resistant malaria: research challenges, opportunities, and public health implications.
Topics: Animals; Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria, Falciparum; Plasmodium falciparum; Public Health | 2012 |
Primaquine for reducing Plasmodium falciparum transmission.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Combinations; Glucosephosphate Dehydrogenase Deficiency; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Primaquine; Pyrimethamine; Quinine; Randomized Controlled Trials as Topic; Sulfadoxine | 2012 |
The need for new antimalarial drugs less prone to resistance.
Topics: Antimalarials; Artemisinins; Chloroquine; Drug Design; Drug Resistance; Drug Therapy, Combination; Global Health; Humans; Malaria, Falciparum; Plasmodium falciparum | 2013 |
Mitigating the threat of artemisinin resistance in Africa: improvement of drug-resistance surveillance and response systems.
Topics: Africa; Africa South of the Sahara; Antimalarials; Artemisinins; Communicable Disease Control; Drug Resistance; Humans; Malaria, Falciparum; Plasmodium falciparum; Sentinel Surveillance; World Health Organization | 2012 |
Rationale for recommending a lower dose of primaquine as a Plasmodium falciparum gametocytocide in populations where G6PD deficiency is common.
Topics: Adult; Anemia, Hemolytic; Animals; Anopheles; Antimalarials; Artemisinins; Drug Therapy, Combination; Female; Glucosephosphate Dehydrogenase; Glucosephosphate Dehydrogenase Deficiency; Humans; Insect Vectors; Malaria, Falciparum; Male; Parasitemia; Plasmodium falciparum; Primaquine | 2012 |
Artemisinin, a novel antimalarial drug: biochemical and molecular approaches for enhanced production.
Topics: Animals; Antimalarials; Artemisia annua; Artemisinins; Genetic Engineering; Humans; Lactones; Malaria, Falciparum; Phytotherapy; Plant Preparations; Plasmodium falciparum; Sesquiterpenes | 2003 |
Chloroquine and artemisinin: six decades of research--what next?
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Genes, Protozoan; Humans; Malaria, Falciparum; Mutation; Plasmodium falciparum; Sesquiterpenes | 2003 |
WHO, the Global Fund, and medical malpractice in malaria treatment.
Topics: Africa; Antimalarials; Artemisinins; Child; Chloroquine; Drug Combinations; Drug Costs; Drug Resistance; Drug Therapy, Combination; Humans; International Agencies; Malaria; Malaria, Falciparum; Malpractice; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Failure; World Health Organization | 2004 |
Management of severe malaria.
Topics: Adolescent; Age Distribution; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Combined Modality Therapy; Developing Countries; Endemic Diseases; Exchange Transfusion, Whole Blood; Female; Humans; Incidence; India; Infant; Malaria, Falciparum; Male; Quinine; Randomized Controlled Trials as Topic; Risk Assessment; Sesquiterpenes; Severity of Illness Index; Sex Distribution | 2004 |
Proteomic approaches to studying drug targets and resistance in Plasmodium.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Computational Biology; Computers; Drug Resistance; Gene Expression Profiling; Genes, Protozoan; Genome, Protozoan; Genomics; Humans; Malaria Vaccines; Malaria, Falciparum; Malaria, Vivax; Mass Spectrometry; Plasmodium; Plasmodium falciparum; Plasmodium vivax; Proteomics; Protozoan Proteins; Sesquiterpenes; Software | 2004 |
A medicinal chemistry perspective on artemisinin and related endoperoxides.
Topics: Alkylation; Antimalarials; Artemisinins; Cysteine Proteinase Inhibitors; Drug Resistance; Drug Stability; Drug Therapy, Combination; Heme; Humans; Malaria, Falciparum; Oxidative Stress; Prodrugs; Sesquiterpenes | 2004 |
Emerging drug--resistance and guidelines for treatment of malaria.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Drug Resistance, Multiple; Drug Therapy, Combination; Follow-Up Studies; Humans; Malaria, Falciparum; Pakistan; Phenanthrenes; Plasmodium falciparum; Quinidine; Quinine; Sesquiterpenes; Time Factors | 2004 |
Malaria in endemic areas.
Topics: Antimalarials; Artemether; Artemisinins; Blood Transfusion; Chloroquine; Deferoxamine; Drug Combinations; Humans; Malaria; Malaria, Falciparum; Pyrimethamine; Quinine; Sesquiterpenes; Sulfadoxine | 2003 |
Progress in the research of artemisinin and its analogues as antimalarials: an update.
Topics: Animals; Antimalarials; Artemisia annua; Artemisinins; Drug Resistance, Multiple; Humans; Malaria, Falciparum; Parasitic Sensitivity Tests; Phytotherapy; Plant Extracts; Plasmodium falciparum; Sesquiterpenes | 2004 |
[Combination therapy as a strategy to prevent antimalarial drug resistance].
Topics: Animals; Antimalarials; Artemisinins; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Plasmodium falciparum; Sesquiterpenes | 2004 |
Population biology and antimalarial resistance: The transmission of antimalarial drug resistance in Plasmodium falciparum.
Topics: Animals; Antimalarials; Artemisinins; Disease Transmission, Infectious; Drug Combinations; Drug Resistance, Multiple; Humans; Malaria, Falciparum; Plasmodium falciparum; Population Density; Pyrimethamine; Sesquiterpenes; Sulfadoxine | 2005 |
Public health impact of drug resistant Plasmodium falciparum malaria.
Topics: Africa; Animals; Antimalarials; Artemisinins; Drug Resistance, Multiple; Health Policy; Humans; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum; Public Health; Sesquiterpenes | 2005 |
Artemisinin-based combinations.
Topics: Adult; Animals; Antimalarials; Artemisinins; Child; Child, Preschool; Clinical Trials as Topic; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Multicenter Studies as Topic; Plasmodium falciparum; Pregnancy; Pregnancy Complications, Parasitic; Randomized Controlled Trials as Topic; Sesquiterpenes; Treatment Outcome | 2005 |
Quinolines and artemisinin: chemistry, biology and history.
Topics: Animals; Antimalarials; Artemisinins; Drug Resistance; Hemeproteins; Hemoglobins; Humans; Malaria, Falciparum; Plasmodium falciparum; Quinolines; Sesquiterpenes | 2005 |
Evidence behind the WHO guidelines: Hospital Care for Children: efficacy and safety of artemisinin derivatives in children with malaria.
Topics: Adolescent; Adult; Animals; Anti-Infective Agents; Antimalarials; Artemisinins; Child; Child, Preschool; Hospitalization; Humans; Malaria, Falciparum; Meta-Analysis as Topic; Plasmodium falciparum; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Sesquiterpenes; World Health Organization | 2006 |
Antimalarial drugs: recent advances in molecular determinants of resistance and their clinical significance.
Topics: Africa; Amino Alcohols; Animals; Antimalarials; Artemisinins; Asia, Southeastern; Biological Transport; Calcium-Transporting ATPases; Chloroquine; Drug Resistance; Drug Resistance, Multiple; Drug Therapy, Combination; Gene Amplification; Humans; Malaria, Falciparum; Mefloquine; Membrane Proteins; Membrane Transport Proteins; Models, Biological; Multidrug Resistance-Associated Proteins; Mutation; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Quinine; Sesquiterpenes | 2006 |
Amodiaquine combined with sulfadoxine/pyrimethamine versus artemisinin-based combinations for the treatment of uncomplicated falciparum malaria in Africa: a meta-analysis.
Topics: Africa; Amodiaquine; Artemisinins; Drug Combinations; Humans; Malaria, Falciparum; Multicenter Studies as Topic; Pyrimethamine; Randomized Controlled Trials as Topic; Sesquiterpenes; Sulfadoxine | 2007 |
Transporters involved in resistance to antimalarial drugs.
Topics: Animals; Antimalarials; Artemisinins; Calcium-Transporting ATPases; Chloroquine; Drug Resistance; Humans; Malaria, Falciparum; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Protozoan Proteins; Sesquiterpenes; Sodium-Hydrogen Exchangers | 2006 |
Artemisinin and chloroquine: do mode of action and mechanism of resistance involve the same protagonists?
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Drugs, Investigational; Humans; Malaria, Falciparum; Molecular Structure; Plasmodium falciparum; Sesquiterpenes | 2007 |
A major transition in malaria treatment: the adoption and deployment of artemisinin-based combination therapies.
Topics: Animals; Anti-Infective Agents; Artemisinins; Drug Resistance, Multiple; Drug Therapy, Combination; Endemic Diseases; Humans; Malaria, Falciparum; Plasmodium falciparum | 2007 |
Qinghaosu (artemisinin): the price of success.
Topics: Animals; Antimalarials; Artemisia; Artemisinins; Cost of Illness; Drug Costs; Drug Resistance; Drug Therapy, Combination; Health Services Accessibility; Humans; Malaria, Falciparum; Plasmodium falciparum | 2008 |
New antimalarials. A risk-benefit analysis.
Topics: Animals; Antimalarials; Artemisinins; Dose-Response Relationship, Drug; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Mefloquine; Phenanthrenes; Plasmodium falciparum; Pregnancy; Risk Assessment; Sesquiterpenes | 1995 |
Progress in the research of artemisinin-related antimalarials: an update.
Topics: Animals; Antimalarials; Artemisinins; Clinical Trials as Topic; Drug Design; Drugs, Chinese Herbal; Humans; Malaria, Falciparum; Sesquiterpenes; Structure-Activity Relationship | 1994 |
Overview of clinical studies on artemisinin derivatives in Thailand.
Topics: Antimalarials; Antiprotozoal Agents; Artemether; Artemisinins; Artesunate; Clinical Trials as Topic; Drug Resistance; Humans; Malaria, Falciparum; Sesquiterpenes; Thailand | 1994 |
An overview of the clinical use of artemisinin and its derivatives in the treatment of falciparum malaria in Viet Nam.
Topics: Adolescent; Adult; Antimalarials; Antiprotozoal Agents; Artemether; Artemisinins; Artesunate; Clinical Trials as Topic; Double-Blind Method; Drug Resistance; Humans; Malaria, Falciparum; Middle Aged; Sesquiterpenes; Vietnam | 1994 |
[The role of qinghaosu derivatives in the treatment of malaria in 1995].
Topics: Antimalarials; Artemether; Artemisinins; Clinical Trials as Topic; Drug Resistance; Forecasting; Humans; Malaria, Falciparum; Sesquiterpenes; Treatment Outcome | 1995 |
[Qinghao derivatives in the treatment of severe malaria].
Topics: Antimalarials; Artemisinins; Clinical Trials as Topic; Humans; Malaria, Falciparum; Sesquiterpenes; Severity of Illness Index | 1995 |
The treatment of malaria.
Topics: Adult; Antimalarials; Artemisinins; Child; Chloroquine; Drug Resistance; Female; Humans; Malaria; Malaria, Falciparum; Pregnancy; Prognosis; Sesquiterpenes | 1996 |
Artemisinin and the antimalarial endoperoxides: from herbal remedy to targeted chemotherapy.
Topics: Animals; Antimalarials; Artemisinins; Clinical Trials as Topic; Drug Resistance; Humans; Malaria; Malaria, Falciparum; Peroxides; Plasmodium falciparum; Sesquiterpenes | 1996 |
Antimalarial activity of artemisinin (qinghaosu) and related trioxanes: mechanism(s) of action.
Topics: Animals; Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum; Sesquiterpenes; Structure-Activity Relationship | 1997 |
[Severe falciparum malaria among travellers to Thailand. Blood exchange and artemisinine treatment are therapeutic alternatives].
Topics: Antimalarials; Antiviral Agents; Artemisinins; Humans; Malaria, Falciparum; Plasma Exchange; Sesquiterpenes; Thailand; Travel | 1997 |
Chemotherapy of parasitic diseases. Current status and new directions.
Topics: Amphotericin B; Antimalarials; Antiprotozoal Agents; Artemisinins; Humans; Leishmaniasis, Visceral; Malaria, Falciparum; Parasitic Diseases; Praziquantel; Schistosomiasis japonica; Schistosomicides; Sesquiterpenes | 1996 |
Artemisinine and its derivatives.
Topics: Antimalarials; Artemisinins; Child; Child, Preschool; Clinical Trials as Topic; Dose-Response Relationship, Drug; Humans; India; Infant; Malaria, Falciparum; Sesquiterpenes; Treatment Outcome | 1997 |
[New drugs in the treatment of malaria].
Topics: Antimalarials; Artemisinins; Contraindications; Denmark; Humans; Malaria, Falciparum; Plant Extracts; Sesquiterpenes | 1998 |
Malaria: new developments in treatment and prevention.
Topics: Antimalarials; Artemisinins; Bedding and Linens; Drug Costs; Drug Resistance; Drugs, Chinese Herbal; Humans; Incidence; Malaria; Malaria Vaccines; Malaria, Falciparum; Protective Devices; Sesquiterpenes; Tropical Climate | 1999 |
How Chinese scientists discovered qinghaosu (artemisinin) and developed its derivatives? What are the future perspectives?
Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Drug Evaluation; Drug Resistance; Forecasting; Humans; Malaria, Falciparum; Medicine, Chinese Traditional; Sesquiterpenes | 1998 |
Artemisinin antimalarials: mechanisms of action and resistance.
Topics: Animals; Antimalarials; Artemisinins; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Resistance; Humans; Malaria, Falciparum; Mice; Plasmodium falciparum; Protozoan Proteins; Sesquiterpenes | 1998 |
Pharmacokinetics and pharmacodynamics of qinghaosu derivatives: how do they impact on the choice of drug and the dosage regimens?
Topics: Administration, Oral; Administration, Rectal; Animals; Antimalarials; Artemisinins; Biological Availability; Chemistry, Pharmaceutical; Decision Making; Drug Monitoring; Humans; Infusions, Intravenous; Injections, Intramuscular; Malaria, Falciparum; Mice; Patient Selection; Practice Guidelines as Topic; Rats; Sesquiterpenes | 1998 |
Use of artemisinin derivatives for the control of malaria.
Topics: Antimalarials; Artemisinins; Drug Resistance; Drug Therapy, Combination; Humans; Incidence; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Prospective Studies; Refugees; Risk Factors; Seasons; Sesquiterpenes; Thailand; Treatment Outcome; Vietnam | 1998 |
Treatment of uncomplicated malaria with artemisinin derivatives. A systematic review of randomised controlled trials.
Topics: Adult; Antimalarials; Artemisinins; Child; Dose-Response Relationship, Drug; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Mefloquine; Randomized Controlled Trials as Topic; Research Design; Sesquiterpenes; Time Factors; Treatment Outcome | 1998 |
Treatment of severe malaria with artemisinin derivatives. A systematic review of randomised controlled trials.
Topics: Adult; Antimalarials; Artemisinins; Chemistry, Pharmaceutical; Child; Humans; Malaria, Cerebral; Malaria, Falciparum; Odds Ratio; Quinine; Randomized Controlled Trials as Topic; Research Design; Sesquiterpenes; Survival Analysis | 1998 |
The rational use of qinghaosu and its derivatives: what is the future of new compounds?
Topics: Administration, Oral; Administration, Rectal; Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Drug and Narcotic Control; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Registries; Sesquiterpenes; Suppositories; Thailand | 1998 |
[Current data on major novel antiamalaria drugs: Artemisinin (qinghaosu) derivatives].
Topics: Antimalarials; Artemisinins; Clinical Trials as Topic; Drugs, Chinese Herbal; Humans; Malaria, Falciparum; Sesquiterpenes; Treatment Outcome | 1999 |
[Why is malaria in Vietnam under control, but Africa is threatened with a malaria disaster?].
Topics: Africa; Animals; Antimalarials; Artemisinins; Communicable Disease Control; Disease Outbreaks; Drug Resistance; Humans; Malaria; Malaria, Falciparum; Mosquito Control; Sesquiterpenes; Vietnam | 2000 |
Artemisinin derivatives for treating uncomplicated malaria.
Topics: Adult; Antimalarials; Artemisinins; Humans; Malaria; Malaria, Falciparum; Sesquiterpenes | 2000 |
Artemisinin derivatives for treating severe malaria.
Topics: Adult; Antimalarials; Artemisinins; Child; Humans; Malaria, Falciparum; Sesquiterpenes | 2000 |
Artemisinin derivatives for falciparum malaria.
Topics: Antimalarials; Artemisinins; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Malaria, Falciparum; Male; Prognosis; Sesquiterpenes; Treatment Outcome | 1999 |
Possible modes of action of the artemisinin-type compounds.
Topics: Animals; Antimalarials; Artemisinins; Humans; Malaria, Falciparum; Plasmodium falciparum; Sesquiterpenes | 2001 |
Severe falciparum malaria in five soldiers from East Timor: a case series and literature review.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Australia; Exchange Transfusion, Whole Blood; Female; Humans; Indonesia; Malaria, Cerebral; Malaria, Falciparum; Military Personnel; Multiple Organ Failure; Sesquiterpenes | 2001 |
A new look at an old drug: artemesinin and qinghaosu.
Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Humans; Malaria, Cerebral; Malaria, Falciparum; Sesquiterpenes | 1992 |
63 trial(s) available for artemisinin and Malaria, Falciparum
| Article | Year |
|---|---|
Artemisinin-piperaquine versus artemether-lumefantrine for treatment of uncomplicated Plasmodium falciparum malaria in Grande Comore island: an open-label, non-randomised controlled trial.
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Drug Combinations; Ethanolamines; Fluorenes; Humans; Malaria; Malaria, Falciparum; Piperazines; Plasmodium falciparum; Quinolines | 2022 |
Overall and Gender-Specific Effects of Intermittent Preventive Treatment of Malaria with Artemisinin-Based Combination Therapies among Schoolchildren in Mali: A Three-Group Open Label Randomized Controlled Trial.
Topics: Amodiaquine; Anemia; Antimalarials; Artemisinins; Artesunate; Child; Drug Combinations; Drug Therapy, Combination; Female; Hemoglobins; Humans; Malaria; Malaria, Falciparum; Mali; Pyrimethamine; Sulfadoxine | 2022 |
Therapeutic response to artemisinin combination therapies among individuals with Plasmodium falciparum single infection vs mixed Plasmodium species infections: a retrospective posthoc analysis in Kisumu County, western Kenya.
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Drug Combinations; Humans; Kenya; Malaria; Malaria, Falciparum; Plasmodium falciparum; Quinolines; Reinfection; Retrospective Studies | 2023 |
Efficacy and safety of pyronaridine-artesunate (PYRAMAX) for the treatment of
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Clinical Trials, Phase III as Topic; Drug Combinations; Female; Humans; Infant; Malaria; Malaria, Falciparum; Pregnancy; Pregnant Women; Randomized Controlled Trials as Topic; Sub-Saharan African People; Treatment Outcome | 2023 |
Optimal timing of primaquine to reduce Plasmodium falciparum gametocyte carriage when co-administered with artemether-lumefantrine.
Topics: Adolescent; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Carrier State; Child; Child, Preschool; Drug Therapy, Combination; Female; Hemoglobins; Humans; Malaria, Falciparum; Male; Plasmodium falciparum; Primaquine; Time Factors | 2020 |
Triple artemisinin-based combination therapies versus artemisinin-based combination therapies for uncomplicated Plasmodium falciparum malaria: a multicentre, open-label, randomised clinical trial.
Topics: Adolescent; Adult; Amodiaquine; Anthraquinones; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Plasmodium falciparum; Polymerase Chain Reaction; Quinolines; Treatment Outcome; Young Adult | 2020 |
Safety and parasite clearance of artemisinin-resistant Plasmodium falciparum infection: A pilot and a randomised volunteer infection study in Australia.
Topics: Adolescent; Adult; Animals; Anti-Infective Agents; Antimalarials; Artemisinins; Artesunate; Australia; Female; Headache; Healthy Volunteers; Humans; Malaria, Falciparum; Male; Nausea; Parasites; Pilot Projects; Plasmodium falciparum; Young Adult | 2020 |
Mass drug administration for the acceleration of malaria elimination in a region of Myanmar with artemisinin-resistant falciparum malaria: a cluster-randomised trial.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Cluster Analysis; Disease Eradication; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Mass Drug Administration; Myanmar; Primaquine; Quinolines; Young Adult | 2021 |
Single dose primaquine to reduce gametocyte carriage and Plasmodium falciparum transmission in Cambodia: An open-label randomized trial.
Topics: Adolescent; Adult; Animals; Anopheles; Antimalarials; Artemisinins; Dose-Response Relationship, Drug; Drug Combinations; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Plasmodium falciparum; Primaquine | 2017 |
Use of malaria rapid diagnostic tests by community health workers in Afghanistan: cluster randomised trial.
Topics: Adolescent; Afghanistan; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Community Health Workers; Diagnostic Tests, Routine; Female; Humans; Infant; Infant, Newborn; Malaria; Malaria, Falciparum; Male; Plasmodium vivax; Trimethoprim, Sulfamethoxazole Drug Combination | 2017 |
Efficacy and Safety of Fosmidomycin-Piperaquine as Nonartemisinin-Based Combination Therapy for Uncomplicated Falciparum Malaria: A Single-Arm, Age De-escalation Proof-of-Concept Study in Gabon.
Topics: Adolescent; Adult; Age Factors; Antimalarials; Artemisinins; Child; Child, Preschool; Combined Modality Therapy; Drug Therapy, Combination; Female; Fosfomycin; Humans; Infant; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Polymerase Chain Reaction; Proof of Concept Study; Quinolines; Treatment Outcome; Young Adult | 2018 |
Population pharmacokinetic and pharmacodynamic properties of artesunate in patients with artemisinin sensitive and resistant infections in Southern Myanmar.
Topics: Antimalarials; Artemisinins; Artesunate; Drug Resistance; Humans; Malaria, Falciparum; Myanmar; Plasmodium falciparum | 2018 |
Therapeutic efficacy of artemisinin combination therapies and prevalence of S769N mutation in PfATPase6 gene of Plasmodium falciparum in Kolkata, India.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Base Sequence; Calcium-Transporting ATPases; Child; Drug Resistance; Drug Therapy, Combination; Female; Genes, Protozoan; Humans; India; Malaria, Falciparum; Male; Middle Aged; Molecular Sequence Data; Mutation; Plasmodium falciparum; Treatment Outcome | 2013 |
Impact of retreatment with an artemisinin-based combination on malaria incidence and its potential selection of resistant strains: study protocol for a randomized controlled clinical trial.
Topics: Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child, Preschool; Clindamycin; Clinical Protocols; Democratic Republic of the Congo; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Incidence; Infant; Longitudinal Studies; Malaria, Falciparum; Male; Plasmodium falciparum; Quinine; Recurrence; Research Design; Retreatment; Time Factors; Treatment Outcome; Uganda | 2013 |
Monitoring the efficacy and safety of three artemisinin based-combinations therapies in Senegal: results from two years surveillance.
Topics: Adolescent; Adult; Amodiaquine; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Combinations; Female; Humans; Malaria, Falciparum; Male; Plasmodium falciparum; Population Surveillance; Quinolines; Senegal; Young Adult | 2013 |
Efficacy and day 7 plasma piperaquine concentrations in African children treated for uncomplicated malaria with dihydroartemisinin-piperaquine.
Topics: Antimalarials; Artemisinins; Burkina Faso; Child; Child, Preschool; Drug Administration Schedule; Drug Combinations; Female; Humans; Infant; Malaria, Falciparum; Male; Quinolines; Treatment Failure | 2014 |
Efficacy of artemisinin-based combination treatments of uncomplicated falciparum malaria in under-five-year-old Nigerian children.
Topics: Amodiaquine; Anemia; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child, Preschool; Drug Combinations; Ethanolamines; Female; Fluorenes; Humans; Malaria, Falciparum; Male; Nigeria; Parasitemia; Prevalence; Treatment Outcome | 2014 |
Economic evaluation of a cluster randomized trial of interventions to improve health workers' practice in diagnosing and treating uncomplicated malaria in Cameroon.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Cameroon; Child; Child, Preschool; Cost-Benefit Analysis; Diagnostic Tests, Routine; Drug Therapy, Combination; Female; Fever; Health Facilities; Health Personnel; Humans; Infant; Inservice Training; Malaria; Malaria, Falciparum; Male; Middle Aged; Young Adult | 2014 |
Artemisinin-naphthoquine versus artemether-lumefantrine for uncomplicated malaria in Papua New Guinean children: an open-label randomized trial.
Topics: Adult; Antimalarials; Artemether; Artemisinins; Ethanolamines; Female; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Male; Middle Aged | 2014 |
Genetic architecture of artemisinin-resistant Plasmodium falciparum.
Topics: Antimalarials; Artemisinins; Drug Resistance; Genetic Predisposition to Disease; Genome-Wide Association Study; Genome, Protozoan; Humans; Malaria, Falciparum; Mutation; Plasmodium falciparum; Polymorphism, Single Nucleotide | 2015 |
Validation and pharmacokinetic application of a high-performance liquid chromatographic technique for determining the concentrations of amodiaquine and its metabolite in plasma of patients treated with oral fixed-dose amodiaquine-artesunate combination in
Topics: Administration, Oral; Adult; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Chromatography, High Pressure Liquid; Drug Combinations; Female; Humans; Malaria; Malaria, Falciparum; Male; Nigeria; Young Adult | 2015 |
Evidence of Plasmodium falciparum Malaria Multidrug Resistance to Artemisinin and Piperaquine in Western Cambodia: Dihydroartemisinin-Piperaquine Open-Label Multicenter Clinical Assessment.
Topics: Adolescent; Adult; Antigens, Bacterial; Antigens, Surface; Antimalarials; Artemisinins; Cambodia; Child; Child, Preschool; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Quinolines; Treatment Failure; Young Adult | 2015 |
Cost-effectiveness of malaria diagnosis using rapid diagnostic tests compared to microscopy or clinical symptoms alone in Afghanistan.
Topics: Adolescent; Adult; Afghanistan; Aged; Animals; Antimalarials; Artemisinins; Child; Child, Preschool; Cost-Benefit Analysis; Diagnostic Tests, Routine; Drug Combinations; Humans; Infant; Malaria, Falciparum; Malaria, Vivax; Microscopy; Middle Aged; Plasmodium falciparum; Plasmodium vivax; Young Adult | 2015 |
Temporal changes in haematocrit following artemisinin-based combination treatments of uncomplicated falciparum malaria in children.
Topics: Administration, Intravenous; Adolescent; Amodiaquine; Anemia; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Child, Preschool; Combined Modality Therapy; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Hematocrit; Humans; Infant; Malaria, Falciparum; Male; Prospective Studies; Treatment Outcome | 2015 |
Clinical illness and outcomes in Nigerian children with late-appearing anaemia after artemisinin-based combination treatments of uncomplicated falciparum malaria.
Topics: Adolescent; Amodiaquine; Anemia; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Nigeria; Prognosis; Quinolines; Risk Factors; Time Factors; Treatment Outcome | 2016 |
Comparison of artesunate-mefloquine and artemether-lumefantrine fixed-dose combinations for treatment of uncomplicated Plasmodium falciparum malaria in children younger than 5 years in sub-Saharan Africa: a randomised, multicentre, phase 4 trial.
Topics: Africa South of the Sahara; Antimalarials; Artemether; Artemisinins; Artesunate; Child, Preschool; Ethanolamines; Female; Fluorenes; Humans; Infant; Lumefantrine; Malaria, Falciparum; Male; Mefloquine; Patient Safety; Polymerase Chain Reaction | 2016 |
Efficacy of Artequick versus artesunate-mefloquine in the treatment of acute uncomplicated falciparum malaria in Thailand.
Topics: Acute Disease; Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Drug Combinations; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Primaquine; Prospective Studies; Quinolines; Thailand; Treatment Outcome | 2008 |
Dose ranging studies of new artemisinin-piperaquine fixed combinations compared to standard regimens of artemisisnin combination therapies for acute uncomplicated falciparum malaria.
Topics: Acute Disease; Adolescent; Adult; Anti-Infective Agents; Antimalarials; Artemisinins; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Prospective Studies; Quinolines; Thailand | 2007 |
Effects of amodiaquine, artesunate, and artesunate-amodiaquine on Plasmodium falciparum malaria-associated anaemia in children.
Topics: Amodiaquine; Anemia; Animals; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Nigeria; Treatment Outcome | 2009 |
Evidence of artemisinin-resistant malaria in western Cambodia.
Topics: Animals; Antimalarials; Artemisinins; Cambodia; Drug Resistance; Humans; Inhibitory Concentration 50; Kaplan-Meier Estimate; Malaria, Falciparum; Plasmodium falciparum; Quinine | 2008 |
Efficacy of oral single dose therapy with artemisinin-naphthoquine phosphate in uncomplicated falciparum malaria.
Topics: Administration, Oral; Adolescent; Adult; Animals; Antimalarials; Artemisinins; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Naphthoquinones; Parasitemia; Plasmodium falciparum; Treatment Outcome; Young Adult | 2009 |
A randomized, controlled trial of artemisinin-piperaquine vs dihydroartemisinin-piperaquine phosphate in treatment of falciparum malaria.
Topics: Adolescent; Adult; Anti-Infective Agents; Antimalarials; Artemisinins; Drug Combinations; Female; Humans; Integrative Medicine; Malaria, Falciparum; Male; Quinolines; Treatment Outcome; Young Adult | 2009 |
A comparative, randomized clinical trial of artemisinin/naphtoquine twice daily one day versus artemether/lumefantrine six doses regimen in children and adults with uncomplicated falciparum malaria in Côte d'Ivoire.
Topics: Adult; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Cote d'Ivoire; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Follow-Up Studies; Humans; Malaria, Falciparum; Male; Plasmodium falciparum; Polymerase Chain Reaction; Recurrence; Treatment Outcome | 2009 |
Therapeutic efficacy and effect on gametocyte carriage of an artemisinin and a non-based combination treatment in children with uncomplicated P. falciparum malaria, living in an area with high-level chloroquine resistance.
Topics: Amodiaquine; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Follow-Up Studies; Gametogenesis; Humans; Infant; Lumefantrine; Malaria, Falciparum; Male; Nigeria; Plasmodium falciparum; Polymerase Chain Reaction; Pyrimethamine; Sulfalene; Treatment Outcome | 2010 |
In Tanzania, hemolysis after a single dose of primaquine coadministered with an artemisinin is not restricted to glucose-6-phosphate dehydrogenase-deficient (G6PD A-) individuals.
Topics: Anemia; Anti-Infective Agents; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Follow-Up Studies; Glucosephosphate Dehydrogenase; Glucosephosphate Dehydrogenase Deficiency; Hemoglobins; Hemolysis; Humans; Infant; Malaria, Falciparum; Multivariate Analysis; Prevalence; Primaquine; Pyrimethamine; Regression Analysis; Risk Factors; Sulfadoxine; Tanzania | 2010 |
Effectiveness of five artemisinin combination regimens with or without primaquine in uncomplicated falciparum malaria: an open-label randomised trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Malaria, Vivax; Male; Mefloquine; Middle Aged; Myanmar; Plasmodium falciparum; Primaquine; Treatment Outcome; Young Adult | 2010 |
Artemisinin resistance in Cambodia: a clinical trial designed to address an emerging problem in Southeast Asia.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Cambodia; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Parasitemia; Plasma; Plasmodium falciparum; Quinine; Recurrence; Tetracycline; Thailand; Treatment Failure; Young Adult | 2010 |
Plasmodium falciparum clearance with artemisinin-based combination therapy (ACT) in patients with glucose-6-phosphate dehydrogenase deficiency in Mali.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Therapy, Combination; Glucosephosphate Dehydrogenase Deficiency; Humans; Infant; Malaria, Falciparum; Mali; Middle Aged; Plasmodium falciparum; Treatment Outcome; Young Adult | 2010 |
Effects of lime juice on malaria parasite clearance.
Topics: Antimalarials; Artemisinins; Child; Child, Preschool; Citrus; Drug Therapy, Combination; Female; Fruit; Humans; Infant; Malaria, Falciparum; Male; Parasite Load; Phytotherapy; Plant Preparations; Plasmodium falciparum; Treatment Failure | 2011 |
Efficacy of chloroquine and sulphadoxine-pyrimethamine either alone or in combination before introduction of ACT as first-line therapy in uncomplicated Plasmodium falciparum malaria in Jalpaiguri District, West Bengal, India.
Topics: Adolescent; Adult; Anti-Infective Agents; Antimalarials; Artemisinins; Child; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Humans; India; Kaplan-Meier Estimate; Malaria, Falciparum; Male; Pyrimethamine; Sulfadoxine; Treatment Outcome; Young Adult | 2011 |
Efficacy of different primaquine-based antimalarial regimens against Plasmodium falciparum gametocytemia.
Topics: Adolescent; Adult; Aged; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Colombia; Drug Combinations; Drug Therapy, Combination; Female; Follow-Up Studies; Germ Cells; Humans; Infant; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Parasitemia; Plasmodium falciparum; Primaquine; Pyrimethamine; Sulfadoxine; Treatment Outcome; Young Adult | 2012 |
No evidence for spread of Plasmodium falciparum artemisinin resistance to Savannakhet Province, Southern Laos.
Topics: Administration, Oral; Adolescent; Adult; Aged; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Child; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Follow-Up Studies; Humans; Laos; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Treatment Outcome; Young Adult | 2012 |
Artemisinin-resistant Plasmodium falciparum in Pursat province, western Cambodia: a parasite clearance rate study.
Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Cambodia; Drug Resistance; Female; Genotype; Glucosephosphate Dehydrogenase; Humans; Malaria, Falciparum; Male; Mefloquine; Microsatellite Repeats; Plasmodium falciparum; Treatment Outcome; Young Adult | 2012 |
Effect of high-dose or split-dose artesunate on parasite clearance in artemisinin-resistant falciparum malaria.
Topics: Administration, Oral; Adolescent; Adult; Antibodies, Protozoan; Antimalarials; Artemisinins; Artesunate; Cambodia; Child; Drug Resistance; Female; Half-Life; Humans; Immunoglobulin G; Malaria, Falciparum; Male; Parasite Load; Parasitemia; Plasmodium falciparum; Thailand; Treatment Outcome; Young Adult | 2013 |
Population pharmacokinetic and pharmacodynamic modelling of artemisinin and mefloquine enantiomers in patients with falciparum malaria.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Drug Interactions; Drug Therapy, Combination; Humans; Malaria, Falciparum; Mefloquine; Middle Aged; Models, Biological; Sesquiterpenes; Stereoisomerism; Structure-Activity Relationship | 2002 |
Therapeutic equivalence of a low dose artemisinin formulation in falciparum malaria patients.
Topics: Adolescent; Adult; Animals; Artemisinins; beta-Cyclodextrins; Cyclodextrins; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Sesquiterpenes; Therapeutic Equivalency; Treatment Outcome | 2003 |
Semi-mechanistic pharmacokinetic/pharmacodynamic modelling of the antimalarial effect of artemisinin.
Topics: Antimalarials; Artemisinins; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Half-Life; Humans; Malaria, Falciparum; Male; Models, Biological; Parasitemia; Saliva; Sesquiterpenes | 2005 |
In vitro activity of artemisinin alone and in combination with retinol against Plasmodium falciparum.
Topics: Adolescent; Adult; Animals; Anti-Infective Agents; Antimalarials; Artemisinins; Child; Dose-Response Relationship, Drug; Drug Combinations; Drug Resistance; Drug Synergism; Female; Humans; Malaria, Falciparum; Male; Parasitic Sensitivity Tests; Plasmodium falciparum; Sesquiterpenes; Treatment Outcome; Vitamin A | 2005 |
Efficacy of chloroquine and sulfadoxine/pyrimethamine for the treatment of uncomplicated falciparum malaria in Koumantou, Mali.
Topics: Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Female; Humans; Infant; Malaria, Falciparum; Male; Pyrimethamine; Recurrence; Sesquiterpenes; Sulfadoxine; Treatment Failure | 2006 |
Efficacy and effectiveness of dihydroartemisinin-piperaquine versus artesunate-mefloquine in falciparum malaria: an open-label randomised comparison.
Topics: Adolescent; Animals; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Mefloquine; Myanmar; Plasmodium falciparum; Quinolines; Recurrence; Sesquiterpenes; Treatment Outcome | 2006 |
Randomized clinical trial of artemisinin versus non-artemisinin combination therapy for uncomplicated falciparum malaria in Madagascar.
Topics: Adolescent; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Humans; Infant; Madagascar; Malaria, Falciparum; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Outcome | 2007 |
[The infectivity of gametocytes of Plasmodium falciparum from patients treated with artemisinine].
Topics: Animals; Anopheles; Antimalarials; Artemisinins; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Sesquiterpenes | 1994 |
Efficacy of oral and intravenous artesunate in male Tanzanian adults with Plasmodium falciparum malaria and in vitro susceptibility to artemisinin, chloroquine, and mefloquine.
Topics: Administration, Oral; Adolescent; Adult; Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drugs, Chinese Herbal; Erythrocytes; Humans; Injections, Intravenous; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Parasitemia; Plasmodium falciparum; Recurrence; Sesquiterpenes; Tanzania | 1995 |
Effects of artemisinin derivatives on malaria transmissibility.
Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Child; Child, Preschool; Disease Transmission, Infectious; Female; Gametogenesis; Humans; Malaria, Falciparum; Male; Patient Compliance; Plasmodium falciparum; Sesquiterpenes; Thailand | 1996 |
Clinical efficacy and pharmacokinetics of artemisinin monotherapy and in combination with mefloquine in patients with falciparum malaria.
Topics: Administration, Oral; Adult; Animals; Antimalarials; Artemisinins; Drug Therapy, Combination; Female; Half-Life; Humans; Malaria, Falciparum; Male; Mefloquine; Sesquiterpenes | 1996 |
Efficacy and tolerance of artemisinin in short combination regimens for the treatment of uncomplicated falciparum malaria.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Child; Doxycycline; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Parasitemia; Quinine; Recurrence; Sesquiterpenes; Treatment Outcome | 1996 |
Comparison of rectal artemisinin with intravenous quinine in the treatment of severe malaria in Ethiopia.
Topics: Administration, Rectal; Adult; Animals; Antimalarials; Artemisinins; Ethiopia; Female; Humans; Infusions, Intravenous; Malaria, Falciparum; Male; Plasmodium falciparum; Quinine; Sesquiterpenes; Severity of Illness Index | 1999 |
Combinations of artemisinin and quinine for uncomplicated falciparum malaria: efficacy and pharmacodynamics.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Metabolic Clearance Rate; Middle Aged; Quinine; Sesquiterpenes; Treatment Outcome | 2000 |
Ex vivo blood schizontocidal activities of artemisinin derivatives against Plasmodium falciparum.
Topics: Administration, Oral; Animals; Antimalarials; Artemisinins; Biological Availability; Cross-Over Studies; Humans; Injections, Intramuscular; Malaria, Falciparum; Plasmodium falciparum; Sesquiterpenes; Statistics, Nonparametric; Suppositories | 1999 |
Effect of artemisinin on lipid peroxidation and fluidity of the erythrocyte membrane in malaria.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Cyclic N-Oxides; Deferoxamine; Double-Blind Method; Erythrocyte Membrane; Humans; Lipid Peroxidation; Malaria; Malaria, Falciparum; Membrane Fluidity; Plasmodium falciparum; Sesquiterpenes; Thiobarbituric Acid Reactive Substances | 2000 |
Artemisinin antimalarials in pregnancy: a prospective treatment study of 539 episodes of multidrug-resistant Plasmodium falciparum.
Topics: Animals; Antimalarials; Artemisinins; Drug Resistance, Multiple; Female; Humans; Malaria, Falciparum; Plasmodium falciparum; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prospective Studies; Sesquiterpenes; Treatment Outcome | 2001 |
Artemisinin for treatment of uncomplicated falciparum malaria: is there a place for monotherapy?
Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Child; Child, Preschool; Disease-Free Survival; Drug Administration Schedule; Drugs, Chinese Herbal; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Phytotherapy; Plasmodium falciparum; Recurrence; Sesquiterpenes; Treatment Outcome | 2001 |
In vivo-in vitro model for the assessment of clinically relevant antimalarial cross-resistance.
Topics: Adult; Animals; Antimalarials; Artemisinins; Chloroquine; Cross Reactions; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Models, Biological; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinine; Recurrence; Sesquiterpenes | 2001 |
497 other study(ies) available for artemisinin and Malaria, Falciparum
| Article | Year |
|---|---|
Selective anti-malarial minor groove binders.
Topics: Antimalarials; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Malaria, Falciparum; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship | 2016 |
Benzoxaborole Antimalarial Agents. Part 5. Lead Optimization of Novel Amide Pyrazinyloxy Benzoxaboroles and Identification of a Preclinical Candidate.
Topics: Amides; Animals; Antimalarials; Boron Compounds; Dogs; Female; Humans; Malaria; Malaria, Falciparum; Male; Mice; Plasmodium berghei; Plasmodium falciparum; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship | 2017 |
MEPicides: α,β-Unsaturated Fosmidomycin Analogues as DXR Inhibitors against Malaria.
Topics: Aldose-Ketose Isomerases; Animals; Antimalarials; Female; Fosfomycin; Malaria, Falciparum; Mice; Plasmodium falciparum; Prodrugs; Structure-Activity Relationship | 2018 |
Synthesis and efficacy of pyrvinium-inspired analogs against tuberculosis and malaria pathogens.
Topics: Antimalarials; Antitubercular Agents; Dose-Response Relationship, Drug; Malaria, Falciparum; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrvinium Compounds; Structure-Activity Relationship; Tuberculosis | 2020 |
Novel molecule combinations and corresponding hybrids targeting artemisinin-resistant Plasmodium falciparum parasites.
Topics: Antimalarials; Artemisinins; Atovaquone; Dose-Response Relationship, Drug; Drug Resistance; Humans; Malaria, Falciparum; Mefloquine; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship; Triclosan | 2021 |
Discovery and Structure-Activity Relationships of Quinazolinone-2-carboxamide Derivatives as Novel Orally Efficacious Antimalarials.
Topics: Administration, Oral; Animals; Antimalarials; Humans; Malaria, Falciparum; Mice; Molecular Structure; Plasmodium falciparum; Quinazolinones; Structure-Activity Relationship | 2021 |
Are Artemisinin-Based Combination Therapies For Malaria Beginning To Fail in Africa?
Topics: Africa; Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria, Falciparum; Plasmodium falciparum | 2021 |
Evidence of Artemisinin-Resistant Malaria in Africa.
Topics: Antimalarials; Artemisinins; Drug Resistance; Humans; Longitudinal Studies; Malaria, Falciparum; Mutation; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Uganda | 2021 |
Lumefantrine attenuates Plasmodium falciparum artemisinin resistance during the early ring stage.
Topics: Antimalarials; Artemisinins; Drug Resistance; Humans; Lumefantrine; Malaria, Falciparum; Plasmodium falciparum; Protozoan Proteins | 2021 |
A New Thienopyrimidinone Chemotype Shows Multistage Activity against Plasmodium falciparum, Including Artemisinin-Resistant Parasites.
Topics: Animals; Antimalarials; Artemisinins; Cell Line, Tumor; Disease Models, Animal; Dogs; Drug Resistance; Female; Hep G2 Cells; Humans; Liver; Macaca fascicularis; Madin Darby Canine Kidney Cells; Malaria, Falciparum; Male; Mice; Mice, Inbred BALB C; Plasmodium cynomolgi; Plasmodium falciparum; Plasmodium yoelii; Pyrimidinones | 2021 |
Plasmodium falciparum rosetting protects schizonts against artemisinin.
Topics: Antimalarials; Artemisinins; Cell Line; Drug Resistance; Erythrocytes; Humans; Malaria, Falciparum; Phagocytosis; Plasmodium falciparum; Rosette Formation | 2021 |
Can repurposing drugs play a role in malaria control?
Topics: Antimalarials; Artemisinins; Drug Repositioning; Drug Resistance, Microbial; Female; Humans; Imatinib Mesylate; Malaria; Malaria, Falciparum; Plasmodium falciparum; Pregnancy; Pregnancy Complications, Parasitic | 2021 |
Will the in situ activator(s) of artemisinin please stand up?
Topics: Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria, Falciparum; Plasmodium falciparum | 2022 |
Circulation of an Artemisinin-Resistant Malaria Lineage in a Traveler Returning from East Africa to France.
Topics: Antimalarials; Artemisinins; Artesunate; Drug Resistance; Humans; Malaria, Falciparum; Plasmodium falciparum; Protozoan Proteins; Uganda | 2022 |
An update on pharmacogenetic factors influencing the metabolism and toxicity of artemisinin-based combination therapy in the treatment of malaria.
Topics: Antimalarials; Artemisinins; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Malaria, Falciparum; Pharmacogenetics; Plasmodium falciparum | 2022 |
Artemisinin resistance in the malaria parasite, Plasmodium falciparum, originates from its initial transcriptional response.
Topics: Animals; Antimalarials; Artemisinins; Drug Resistance; Malaria, Falciparum; Parasites; Plasmodium falciparum | 2022 |
Dimeric Artesunate Glycerophosphocholine Conjugate Nano-Assemblies as Slow-Release Antimalarials to Overcome Kelch 13 Mutant Artemisinin Resistance.
Topics: Antimalarials; Artemisinins; Artesunate; Cryoelectron Microscopy; Drug Resistance; Humans; Liposomes; Malaria; Malaria, Falciparum; Plasmodium falciparum | 2022 |
Is triple artemisinin-based combination therapy necessary for uncomplicated malaria?
Topics: Antimalarials; Artemisinins; Drug Combinations; Drug Therapy, Combination; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum | 2022 |
Is triple artemisinin-based combination therapy necessary for uncomplicated malaria?
Topics: Antimalarials; Artemisinins; Drug Combinations; Drug Therapy, Combination; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum | 2022 |
The first case of artemisinin treatment failure of Plasmodium falciparum imported to Oman from Tanzania.
Topics: Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria, Falciparum; Oman; Plasmodium falciparum; Tanzania; Treatment Failure | 2023 |
Plasmodium falciparum sexual conversion rates can be affected by artemisinin-based treatment in naturally infected malaria patients.
Topics: Animals; Antimalarials; Artemisinins; Canada; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum | 2022 |
Impact of Drug Exposure on Resistance Selection Following Artemether-Lumefantrine Treatment for Malaria in Children With and Without HIV in Uganda.
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Drug Combinations; Fluorenes; HIV Infections; Humans; Lopinavir; Lumefantrine; Malaria; Malaria, Falciparum; Nevirapine; Ritonavir; Uganda | 2023 |
The protein aggregation inhibitor YAT2150 has potent antimalarial activity in Plasmodium falciparum in vitro cultures.
Topics: Amyloid beta-Peptides; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Humans; Malaria, Falciparum; Plasmodium falciparum; Protein Aggregates; Proteome | 2022 |
Apicoplast ribosomal protein S10-V127M enhances artemisinin resistance of a Kelch13 transgenic Plasmodium falciparum.
Topics: Antimalarials; Apicoplasts; Artemisinins; Drug Resistance; Genome-Wide Association Study; Humans; Malaria, Falciparum; Mutation; Plasmodium falciparum; Protozoan Proteins | 2022 |
Targeting Artemisinin-Resistant Malaria by Repurposing the Anti-Hepatitis C Virus Drug Alisporivir.
Topics: Antimalarials; Artemisinins; Cyclosporine; Drug Repositioning; Drug Resistance; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum | 2022 |
Malaria outbreak in Laos caused by formerly rare artemisinin resistant strains of Plasmodium falciparum.
Topics: Antimalarials; Artemisinins; Drug Resistance; Humans; Laos; Malaria; Malaria, Falciparum; Plasmodium falciparum | 2023 |
Molecular surveillance of artemisinin resistance-related Pfk13 and pfcrt polymorphisms in imported Plasmodium falciparum isolates reported in eastern China from 2015 to 2019.
Topics: Artemisinins; China; Humans; Malaria, Falciparum; Plasmodium falciparum; Retrospective Studies | 2022 |
Prevalence and characterization of piperaquine, mefloquine and artemisinin derivatives triple-resistant Plasmodium falciparum in Cambodia.
Topics: Antimalarials; Artemisinins; Artesunate; Cambodia; Drug Resistance; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Prevalence; Quinolines | 2023 |
The Impact of Sequestration on Artemisinin-Induced Parasite Clearance in Plasmodium falciparum Malaria in Africa.
Topics: Animals; Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria, Falciparum; Parasitemia; Parasites; Plasmodium falciparum; Protozoan Proteins; Uganda | 2023 |
Dinuclear and mononuclear metal(II) polypyridyl complexes against drug-sensitive and drug-resistant Plasmodium falciparum and their mode of action.
Topics: Antimalarials; Artemisinins; Coordination Complexes; Copper; Drug Resistance; Humans; Malaria; Malaria, Falciparum; Metals; Plasmodium falciparum; Zinc | 2022 |
Short tandem repeat polymorphism in the promoter region of cyclophilin 19B drives its transcriptional upregulation and contributes to drug resistance in the malaria parasite Plasmodium falciparum.
Topics: Antimalarials; Cyclophilins; Drug Resistance; Humans; Malaria, Falciparum; Microsatellite Repeats; Plasmodium falciparum; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Protozoan Proteins; Up-Regulation | 2023 |
Molecular surveillance of Kelch-13 gene in Plasmodium falciparum field isolates from Mayurbhanj District, Odisha, India, and in silico artemisinin-Kelch-13 protein interaction study.
Topics: Antimalarials; Artemisinins; Drug Resistance; Humans; India; Malaria, Falciparum; Molecular Docking Simulation; Mutation; Plasmodium falciparum; Protozoan Proteins | 2023 |
Assessment of artemisinin tolerance in Plasmodium falciparum clinical isolates in children with uncomplicated malaria in Ghana.
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Drug Combinations; Drug Tolerance; Ghana; Humans; Lumefantrine; Malaria; Malaria, Falciparum; Plasmodium falciparum | 2023 |
In vitro activity of rhinacanthin analogues against drug resistant Plasmodium falciparum isolates from Northeast Thailand.
Topics: Antimalarials; Atovaquone; Cytochromes b; Drug Resistance; Humans; Malaria, Falciparum; Plasmodium falciparum; Thailand | 2023 |
Mitigating the risk of antimalarial resistance via covalent dual-subunit inhibition of the Plasmodium proteasome.
Topics: Antimalarials; Artemisinins; Humans; Malaria, Falciparum; Plasmodium; Proteasome Endopeptidase Complex; Proteasome Inhibitors | 2023 |
[POST-ARTEMISININ DELAYED HEMOLYSIS AFTER TREATMENT OF MALARIA].
Topics: Anemia; Antimalarials; Artemisinins; Hemolysis; Humans; Malaria; Malaria, Falciparum | 2023 |
Evolution of Plasmodium falciparum antimalarial drug resistance markers post-adoption of artemisinin-based combination therapies in Yaounde, Cameroon.
Topics: Antimalarials; Artemisinins; Cameroon; Drug Combinations; Humans; Malaria, Falciparum; Plasmodium falciparum; Protozoan Proteins; Sulfadoxine | 2023 |
Modified Plasmodium falciparum Ring-Stage Survival Assay with ML10 Kinase Inhibitor.
Topics: Animals; Antimalarials; Antineoplastic Agents; Artemisinins; Drug Resistance; Malaria, Falciparum; Plasmodium falciparum; Protein Kinase Inhibitors; Schizonts | 2023 |
Susceptibility of Southeast Asian Plasmodium falciparum isolates to P218.
Topics: Antimalarials; Artemisinins; Drug Resistance; Folic Acid Antagonists; Humans; Malaria, Falciparum; Plasmodium falciparum; Pyrimethamine | 2023 |
Monitoring antimalarial drug-resistance markers in Somalia.
Topics: Antimalarials; Chloroquine; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum; Somalia | 2023 |
Anti-malarial resistance in Mozambique: Absence of Plasmodium falciparum Kelch 13 (K13) propeller domain polymorphisms associated with resistance to artemisinins.
Topics: Antimalarials; Artemisinins; Cross-Sectional Studies; Drug Resistance; Humans; Malaria, Falciparum; Mozambique; Mutation; Plasmodium falciparum; Protozoan Proteins | 2023 |
A novel Modulator of Ring Stage Translation (MRST) gene alters artemisinin sensitivity in
Topics: Antimalarials; Artemisinins; Humans; Malaria, Falciparum; Plasmodium falciparum | 2023 |
Ex vivo RSA and pfkelch13 targeted-amplicon deep sequencing reveal parasites susceptibility to artemisinin in Senegal, 2017.
Topics: Animals; Antimalarials; Artemisinins; Drug Resistance; High-Throughput Nucleotide Sequencing; Humans; Malaria, Falciparum; Mutation; Parasites; Plasmodium falciparum; Protozoan Proteins; Senegal; Uganda | 2023 |
Activity of Ivermectin and Its Metabolites against Asexual Blood Stage Plasmodium falciparum and Its Interactions with Antimalarial Drugs.
Topics: Animals; Antimalarials; Artemisinins; Drug Combinations; Drug Resistance; Humans; Ivermectin; Malaria; Malaria, Falciparum; Plasmodium falciparum | 2023 |
Multi-omics dissection of stage-specific artemisinin tolerance mechanisms in Kelch13-mutant Plasmodium falciparum.
Topics: Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria, Falciparum; Multiomics; Mutation; Plasmodium falciparum; Protozoan Proteins | 2023 |
An artesunate pharmacometric model to explain therapeutic responses in falciparum malaria.
Topics: Antimalarials; Artemisinins; Artesunate; Bayes Theorem; Drug Resistance; Humans; Malaria, Falciparum; Plasmodium falciparum | 2023 |
Application of loop-mediated isothermal amplification combined with lateral flow assay visualization of Plasmodium falciparum kelch 13 C580Y mutation for artemisinin resistance detection in clinical samples.
Topics: Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria; Malaria, Falciparum; Mutation; Plasmodium falciparum | 2023 |
Nationwide spatiotemporal drug resistance genetic profiling from over three decades in Indian Plasmodium falciparum and Plasmodium vivax isolates.
Topics: Antimalarials; Artemisinins; Drug Resistance; Genetic Profile; Humans; India; Malaria, Falciparum; Malaria, Vivax; Plasmodium falciparum; Plasmodium vivax; Protozoan Proteins | 2023 |
Therapeutic efficacy of artesunate-amodiaquine and artemether-lumefantrine for the treatment of uncomplicated falciparum malaria in Chad: clinical and genetic surveillance.
Topics: Adult; Amodiaquine; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Chad; Female; Humans; Malaria, Falciparum; Pregnancy; Prospective Studies | 2023 |
Artemisinin resistance in P. falciparum: probing the interacting partners of Kelch13 protein in parasite.
Topics: Aldehyde-Lyases; Animals; Antimalarials; Artemisinins; Drug Resistance; Fructose; HSP70 Heat-Shock Proteins; Malaria, Falciparum; Merozoite Surface Protein 1; Mutation; Parasites; Plasmodium falciparum; Protozoan Proteins | 2023 |
Plasmodium falciparum resistant to artemisinin and diagnostics have emerged in Ethiopia.
Topics: Antimalarials; Artemisinins; Ethiopia; Humans; Malaria, Falciparum; Plasmodium falciparum; Protozoan Proteins | 2023 |
Strategies for deploying triple artemisinin-based combination therapy in the Greater Mekong Subregion.
Topics: Artemisinins; Cambodia; Health Personnel; Humans; Information Dissemination; Malaria, Falciparum | 2023 |
Topics: Antimalarials; Artemisinins; Drug Resistance; Glucose; Humans; Malaria, Falciparum; Plasmodium falciparum; Protozoan Proteins | 2023 |
The temporal dynamics of Plasmodium species infection after artemisinin-based combination therapy (ACT) among asymptomatic children in the Hohoe municipality, Ghana.
Topics: Artemisinins; Child; Ghana; Humans; Malaria; Malaria, Falciparum; Nucleic Acids; Plasmodium malariae | 2023 |
Screening for K13-Propeller Mutations Associated with Artemisinin Resistance in Plasmodium falciparum in Yambio County (Western Equatoria State, South Sudan).
Topics: Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria, Falciparum; Mutation; Plasmodium falciparum; Protozoan Proteins; South Sudan | 2023 |
Artemisinin-Resistant and HRP-Negative Malaria Parasites in Africa.
Topics: Africa; Animals; Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria; Malaria, Falciparum; Plasmodium; Plasmodium falciparum | 2023 |
Modeling to guide drug policy response to artemisinin-resistant malaria in Rwanda.
Topics: Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum; Policy; Rwanda | 2023 |
Molecular characterization of the Plasmodium falciparum k13 gene helix domain in samples from native communities of Condorcanqui, Amazonas, Perú
Topics: Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria, Falciparum; Peru; Plasmodium falciparum; Protozoan Proteins | 2023 |
Concerns over stable artemisinin resistance in Uganda.
Topics: Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria, Falciparum; Plasmodium falciparum; Uganda | 2023 |
What exactly does the PfK13 C580Y mutation in Plasmodium falciparum influence?
Topics: Animals; Antimalarials; Artemisinins; Drug Resistance; Iron; Malaria, Falciparum; Mutation; Plasmodium falciparum; Protozoan Proteins | 2023 |
The volatilome signatures of Plasmodium falciparum parasites during the intraerythrocytic development cycle in vitro under exposure to artemisinin drug.
Topics: Animals; Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria; Malaria, Falciparum; Parasites; Plasmodium falciparum; Protozoan Proteins; Volatile Organic Compounds | 2023 |
[PGE1-assisted treatment of microcirculation disturbance in complicated falciparum malaria].
Topics: Administration, Intravenous; Adult; Alprostadil; Artemisinins; Humans; Malaria, Falciparum; Male; Microcirculation | 2019 |
Plasmodium falciparum Kelch Propeller Polymorphisms in Clinical Isolates from Ghana from 2007 to 2016.
Topics: Antimalarials; Artemisinins; Child; Drug Resistance; Female; Genotype; Ghana; Humans; Malaria, Falciparum; Male; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins | 2019 |
Major subpopulations of
Topics: Antimalarials; Artemisinins; Drug Resistance; Ethiopia; Genetic Loci; Ghana; Haplotypes; Humans; Malaria, Falciparum; Malawi; Plasmodium falciparum; Polymorphism, Single Nucleotide; Selection, Genetic | 2019 |
Efficacy of artemisinin-based and quinine-based treatments for uncomplicated falciparum malaria in pregnancy: a protocol for systematic review and individual patient data (IPD) meta-analysis.
Topics: Antimalarials; Artemisinins; Female; Humans; Malaria, Falciparum; Meta-Analysis as Topic; Pregnancy; Pregnancy Complications, Infectious; Quinine; Records; Risk Factors; Systematic Reviews as Topic | 2019 |
K-13 propeller gene polymorphisms isolated between 2014 and 2017 from Cameroonian Plasmodium falciparum malaria patients.
Topics: Alleles; Antimalarials; Artemisinins; Cameroon; Child; Child, Preschool; Drug Resistance; Female; Genes, Protozoan; Humans; Kelch Repeat; Malaria, Falciparum; Male; Mutation; Plasmodium falciparum; Polymorphism, Genetic; Prospective Studies; Protozoan Proteins | 2019 |
Molecular Surveillance of Pfkelch13 and Pfmdr1 Mutations in Plasmodium falciparum Isolates from Southern Thailand.
Topics: Antimalarials; Artemisinins; Base Sequence; DNA, Protozoan; Drug Combinations; Drug Resistance; Genes, MDR; Genetic Markers; Humans; Kelch Repeat; Malaria, Falciparum; Mutation; Plasmodium falciparum; Polymerase Chain Reaction; Thailand | 2019 |
Quantitative and rapid Plasmodium falciparum malaria diagnosis and artemisinin-resistance detection using a CMOS Lab-on-Chip platform.
Topics: Animals; Artemisinins; Biosensing Techniques; Humans; Lab-On-A-Chip Devices; Malaria, Falciparum; Molecular Diagnostic Techniques; Plasmodium falciparum; Point-of-Care Systems; Semiconductors | 2019 |
Genetic mapping of fitness determinants across the malaria parasite Plasmodium falciparum life cycle.
Topics: Animals; Anopheles; Antimalarials; Artemisinins; Chromosome Mapping; Disease Models, Animal; Drug Resistance; Female; Gene Frequency; Genetic Loci; Host-Parasite Interactions; Humans; Life Cycle Stages; Malaria, Falciparum; Male; Mice; Mosquito Vectors; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Ribosomal Proteins; Selection, Genetic; Transplantation Chimera | 2019 |
A multilamellar nanoliposome stabilized by interlayer hydrogen bonds increases antimalarial drug efficacy.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Cross-Linking Reagents; Drug Delivery Systems; Hydrogen Bonding; Liposomes; Malaria, Falciparum; Mice, Inbred BALB C; Mice, Inbred C57BL; Nanoparticles; Particle Size; Plasmodium falciparum; Treatment Outcome | 2019 |
Prevalence of mutations in Plasmodium falciparum genes associated with resistance to different antimalarial drugs in Nyando, Kisumu County in Kenya.
Topics: Antimalarials; Artemisinins; ATP Binding Cassette Transporter, Subfamily B, Member 1; Child; Child, Preschool; Drug Resistance, Microbial; Humans; Infant; Kenya; Malaria, Falciparum; Mutation; Plasmodium falciparum; Polymorphism, Single Nucleotide; Prevalence; Protozoan Proteins | 2020 |
Decreased K13 Abundance Reduces Hemoglobin Catabolism and Proteotoxic Stress, Underpinning Artemisinin Resistance.
Topics: Artemisinins; Hemoglobins; Humans; Malaria, Falciparum; Mutation; Plasmodium falciparum | 2019 |
Dealing with indeterminate outcomes in antimalarial drug efficacy trials: a comparison between complete case analysis, multiple imputation and inverse probability weighting.
Topics: Antimalarials; Artemisinins; Data Interpretation, Statistical; Humans; Likelihood Functions; Malaria, Falciparum; Plasmodium falciparum; Probability; Recurrence; Treatment Outcome | 2019 |
Rubber plantations and drug resistant malaria: a cross-sectional survey in Cambodia.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Cambodia; Cross-Sectional Studies; Drug Resistance; Female; Forestry; Hevea; Humans; Malaria, Falciparum; Malaria, Vivax; Male; Middle Aged; Occupational Diseases; Plasmodium falciparum; Plasmodium vivax; Prevalence; Risk Factors; Young Adult | 2019 |
Molecular Surveillance for Polymorphisms Associated with Artemisinin-Based Combination Therapy Resistance in
Topics: Artemisinins; ATP-Binding Cassette Transporters; Brazil; Drug Resistance; Humans; Malaria, Falciparum; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins | 2020 |
A Kelch13-defined endocytosis pathway mediates artemisinin resistance in malaria parasites.
Topics: Antimalarials; Artemisinins; Drug Resistance; Endocytosis; Hemoglobins; Humans; Malaria, Falciparum; Mutation; Plasmodium falciparum; Protozoan Proteins | 2020 |
Efavirenz-Based Antiretroviral Therapy Reduces Artemether-Lumefantrine Exposure for Malaria Treatment in HIV-Infected Pregnant Women.
Topics: Adolescent; Adult; Alkynes; Anti-HIV Agents; Anti-Retroviral Agents; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Benzoxazines; Cyclopropanes; Drug Combinations; Drug Interactions; Female; HIV Infections; Humans; Lumefantrine; Malaria; Malaria, Falciparum; Pregnancy; Prospective Studies; Uganda; Young Adult | 2020 |
Antimalarial Drug Resistance Profiling of Plasmodium falciparum Infections in Ghana Using Molecular Inversion Probes and Next-Generation Sequencing.
Topics: Adolescent; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Ghana; High-Throughput Nucleotide Sequencing; Humans; Infant; Malaria, Falciparum; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrimethamine; Sulfadoxine | 2020 |
The extended recovery ring-stage survival assay provides a superior association with patient clearance half-life and increases throughput.
Topics: Antimalarials; Artemisinins; Benzothiazoles; Diamines; Drug Resistance; Erythrocytes; Flow Cytometry; Fluorescent Dyes; Half-Life; Humans; Malaria, Falciparum; Organic Chemicals; Parasitemia; Plasmodium falciparum; Povidone; Quinolines; Real-Time Polymerase Chain Reaction; Silicon Dioxide | 2020 |
Malaria epidemiology in Kobeni department, southeastern Mauritania from 2015 to 2017.
Topics: Adolescent; Antimalarials; Artemisinins; Child; Child, Preschool; Coinfection; Diagnostic Tests, Routine; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Malaria, Vivax; Male; Mauritania; Plasmodium falciparum; Plasmodium vivax; Seasons | 2020 |
Role of Plasmodium falciparum Kelch 13 Protein Mutations in P. falciparum Populations from Northeastern Myanmar in Mediating Artemisinin Resistance.
Topics: Antimalarials; Artemisinins; Asia, Southeastern; Drug Resistance; Humans; Malaria, Falciparum; Mutation; Organisms, Genetically Modified; Plasmodium falciparum; Protozoan Proteins | 2020 |
Why is WHO failing women with falciparum malaria in the first trimester of pregnancy?
Topics: Adult; Antimalarials; Artemisinins; Female; Humans; Malaria, Falciparum; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications, Parasitic; Pregnancy Trimester, First; World Health Organization | 2020 |
A Biosynthetic Platform for Antimalarial Drug Discovery.
Topics: Actin Cytoskeleton; Antimalarials; Artemisinins; Biosynthetic Pathways; Drug Discovery; Drug Resistance; Escherichia coli; High-Throughput Screening Assays; Humans; Indoles; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum; Synthetic Biology | 2020 |
Targeted deep amplicon sequencing of kelch 13 and cytochrome b in Plasmodium falciparum isolates from an endemic African country using the Malaria Resistance Surveillance (MaRS) protocol.
Topics: Africa; Anti-Infective Agents; Antimalarials; Artemisinins; Atovaquone; Cytochromes b; DNA, Protozoan; Drosophila Proteins; Drug Combinations; Drug Resistance; Genotype; High-Throughput Nucleotide Sequencing; Humans; Italy; Malaria, Falciparum; Microfilament Proteins; Plasmodium falciparum; Polymorphism, Single Nucleotide; Prevalence; Proguanil; Protozoan Proteins; Travel | 2020 |
Sequence Analysis of the
Topics: Antimalarials; Artemisinins; Drug Resistance; Humans; India; Malaria, Falciparum; Plasmodium falciparum; Polymorphism, Genetic; Protein Domains; Protozoan Proteins | 2020 |
Insights into the intracellular localization, protein associations and artemisinin resistance properties of Plasmodium falciparum K13.
Topics: Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria, Falciparum; Mutation; Plasmodium falciparum; Protozoan Proteins | 2020 |
Experimentally Engineered Mutations in a Ubiquitin Hydrolase, UBP-1, Modulate
Topics: Africa; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Humans; Hydrolases; Malaria, Falciparum; Mutation; Plasmodium berghei; Plasmodium falciparum; Prospective Studies; Protozoan Proteins; Ubiquitin | 2020 |
Evolution of Antimalarial Drug Resistance Markers in the Reservoir of Plasmodium falciparum Infections in the Upper East Region of Ghana.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alleles; Antimalarials; Artemisinins; Child; Child, Preschool; Cross-Sectional Studies; Drug Resistance; Female; Genetic Variation; Genetics, Population; Genotype; Ghana; Haplotypes; Humans; Infant; Malaria, Falciparum; Male; Membrane Transport Proteins; Middle Aged; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Protozoan Proteins; Young Adult | 2020 |
Non-synonymous amino acid alterations in PfEBA-175 modulate the merozoite ligand's ability to interact with host's Glycophorin A receptor.
Topics: Amino Acid Substitution; Animals; Antimalarials; Artemisinins; Artesunate; Erythrocytes; Glycophorins; Host-Parasite Interactions; Humans; Intracellular Signaling Peptides and Proteins; Malaria, Falciparum; Molecular Docking Simulation; Plasmodium falciparum; Polymorphism, Genetic; Protein Binding; Protein Domains; Protein Folding; Protozoan Proteins; Recombinant Proteins | 2020 |
Identification of compounds active against quiescent artemisinin-resistant Plasmodium falciparum parasites via the quiescent-stage survival assay (QSA).
Topics: Animals; Antimalarials; Artemisinins; Cambodia; Drug Resistance; Malaria, Falciparum; Parasites; Plasmodium falciparum; Protozoan Proteins | 2020 |
Molecular epidemiology of resistance to antimalarial drugs in the Greater Mekong subregion: an observational study.
Topics: Antimalarials; Artemisinins; Asia, Southeastern; Genetic Markers; Haplotypes; Humans; Malaria, Falciparum; Molecular Epidemiology; Plasmodium falciparum | 2020 |
Emergence and clonal expansion of in vitro artemisinin-resistant Plasmodium falciparum kelch13 R561H mutant parasites in Rwanda.
Topics: Amino Acid Substitution; Animals; Antimalarials; Arginine; Artemisinins; Clonal Evolution; Communicable Diseases, Emerging; Drug Resistance; Genotype; Histidine; Humans; In Vitro Techniques; Kelch Repeat; Malaria, Falciparum; Mutation, Missense; Parasitic Sensitivity Tests; Phylogeny; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Rwanda | 2020 |
The lack of K13-propeller mutations associated with artemisinin resistance in Plasmodium falciparum in Democratic Republic of Congo (DRC).
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Child; Child, Preschool; Democratic Republic of the Congo; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Mutation; Plasmodium falciparum; Polymorphism, Genetic; Young Adult | 2020 |
No evidence of amplified Plasmodium falciparum plasmepsin II gene copy number in an area with artemisinin-resistant malaria along the China-Myanmar border.
Topics: Antimalarials; Artemisinins; Aspartic Acid Endopeptidases; China; Drug Resistance; Gene Dosage; Malaria, Falciparum; Myanmar; Plasmodium falciparum; Protozoan Proteins | 2020 |
Genetic screens reveal a central role for heme metabolism in artemisinin susceptibility.
Topics: Antimalarials; Artemisinins; Clustered Regularly Interspaced Short Palindromic Repeats; Drug Resistance; Gene Knockout Techniques; Genetic Testing; Heme; Humans; Malaria, Falciparum; Membrane Transport Proteins; Mutation; Plasmodium falciparum; Protozoan Proteins; Toxoplasma | 2020 |
Molecular detection of drug resistant polymorphisms in Plasmodium falciparum isolates from Southwest, Nigeria.
Topics: Adolescent; Adult; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Calcium-Transporting ATPases; Child; Child, Preschool; Coronavirus Infections; COVID-19; Drug Resistance; Female; Gene Expression; Genotype; Humans; Infant; Malaria, Falciparum; Membrane Transport Proteins; Middle Aged; Molecular Epidemiology; Multidrug Resistance-Associated Proteins; Mutation; Nigeria; Pandemics; Plasmodium falciparum; Pneumonia, Viral; Protozoan Proteins | 2020 |
Elucidation of DNA Repair Function of PfBlm and Potentiation of Artemisinin Action by a Small-Molecule Inhibitor of RecQ Helicase.
Topics: Antimalarials; Artemisinins; Chloroquine; DNA Repair; Enzyme Inhibitors; Humans; Malaria, Falciparum; Plasmodium falciparum; Protozoan Proteins; RecQ Helicases | 2020 |
Emergence of artemisinin-resistant Plasmodium falciparum with kelch13 C580Y mutations on the island of New Guinea.
Topics: Anti-Infective Agents; Artemisinins; Cross-Sectional Studies; Drug Resistance; Genes, Protozoan; Humans; Malaria, Falciparum; Mutation; Papua New Guinea; Plasmodium falciparum | 2020 |
Histone acetyltransferase PfGCN5 regulates stress responsive and artemisinin resistance related genes in Plasmodium falciparum.
Topics: Antimalarials; Artemisinins; Drug Resistance; Histone Acetyltransferases; Humans; Malaria; Malaria, Falciparum; p300-CBP Transcription Factors; Plasmodium falciparum; Protozoan Proteins; Stress, Physiological | 2021 |
Towards one standard treatment for uncomplicated Plasmodium falciparum and Plasmodium vivax malaria: Perspectives from and for the Peruvian Amazon.
Topics: Adult; Aminoquinolines; Artemisinins; Female; Humans; Malaria, Falciparum; Malaria, Vivax; Peru; Plasmodium falciparum; Plasmodium vivax; Prevalence; Primaquine; Reference Standards | 2021 |
A LAMP-SNP Assay Detecting C580Y Mutation in Pfkelch13 Gene from Clinically Dried Blood Spot Samples.
Topics: Antimalarials; Artemisinins; Blood; Blood Specimen Collection; DNA Mutational Analysis; DNA, Protozoan; Drug Resistance; Genes, Protozoan; Humans; Malaria, Falciparum; Molecular Diagnostic Techniques; Mutation; Nucleic Acid Amplification Techniques; Plasmodium falciparum; Polymorphism, Single Nucleotide | 2021 |
In vitro growth competition experiments that suggest consequences of the substandard artemisinin epidemic that may be accelerating drug resistance in P. falciparum malaria.
Topics: Antimalarials; Artemisinins; Asia, Southeastern; Drug Resistance; Humans; Malaria, Falciparum; Plasmodium falciparum | 2021 |
Association of Plasmodium falciparum kelch13 R561H genotypes with delayed parasite clearance in Rwanda: an open-label, single-arm, multicentre, therapeutic efficacy study.
Topics: Animals; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child, Preschool; Drug Resistance; Female; Genotype; Humans; Infant; Malaria, Falciparum; Male; Mutation, Missense; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Rwanda | 2021 |
Artemisinin combination therapy fails even in the absence of Plasmodium falciparum kelch13 gene polymorphism in Central India.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Drug Resistance; Drug Therapy, Combination; Female; Humans; India; Kelch Repeat; Malaria; Malaria, Falciparum; Male; Middle Aged; Mutation; Phenotype; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Pyrimethamine; Sulfadoxine; Tetrahydrofolate Dehydrogenase; Treatment Outcome | 2021 |
An integrated virtual screening and drug repurposing strategy for the discovery of new antimalarial drugs against Plasmodium falciparum phosphatidylinositol 3-kinase.
Topics: Antimalarials; Artemisinins; Drug Development; Drug Repositioning; Drug Resistance; High-Throughput Screening Assays; Humans; Malaria, Falciparum; Phosphatidylinositol 3-Kinase; Plasmodium falciparum; Protozoan Proteins | 2021 |
Methodological approaches for analysing data from therapeutic efficacy studies.
Topics: Antimalarials; Artemisinins; Communicable Disease Control; Data Analysis; Disease Eradication; Drug Combinations; Humans; Malaria, Falciparum; Plasmodium falciparum; Randomized Controlled Trials as Topic | 2021 |
Selection of
Topics: Alleles; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Protozoan Proteins | 2021 |
Mapping partner drug resistance to guide antimalarial combination therapy policies in sub-Saharan Africa.
Topics: Africa South of the Sahara; Antimalarials; Artemisinins; Bayes Theorem; Drug Resistance; Genotype; Humans; Malaria, Falciparum; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Mutation; Plasmodium falciparum; Protozoan Proteins | 2021 |
Topics: Africa; Antimalarials; Artemisinins; Asia; Cambodia; Drug Resistance; Humans; Malaria, Falciparum; Molecular Epidemiology; Mutation; Plasmodium falciparum; Protozoan Proteins | 2021 |
The apicoplast link to fever-survival and artemisinin-resistance in the malaria parasite.
Topics: Animals; Apicoplasts; Artemisinins; Drug Resistance; Fever; Gene Expression Regulation; Heat-Shock Response; Malaria, Falciparum; Mutation; Parasites; Phenotype; Plasmodium falciparum; Signal Transduction; Temperature; Terpenes; Transcription, Genetic; Unfolded Protein Response | 2021 |
Analysis of drug resistance marker genes of
Topics: Animals; Artemisinins; Biomarkers; Drug Resistance; Drug Therapy, Combination; India; Malaria, Falciparum; Mutation; Plasmodium falciparum | 2021 |
A heat-shock response regulated by the PfAP2-HS transcription factor protects human malaria parasites from febrile temperatures.
Topics: Antimalarials; Artemisinins; Fever; Gene Expression Regulation; Heat-Shock Response; Hot Temperature; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; Malaria, Falciparum; Plasmodium falciparum; Proteostasis; Protozoan Proteins; Transcription Factors | 2021 |
Multi-omics Based Identification of Specific Biochemical Changes Associated With PfKelch13-Mutant Artemisinin-Resistant Plasmodium falciparum.
Topics: Artemisinins; Drug Resistance; Humans; Malaria, Falciparum; Metabolomics; Models, Biological; Mutation; Plasmodium falciparum; Proteomics; Protozoan Proteins | 2017 |
Prolonged parasite clearance in a Chinese splenectomized patient with falciparum malaria imported from Nigeria.
Topics: Adult; Animals; Antimalarials; Artemisinins; China; Humans; Malaria, Falciparum; Male; Nigeria; Plasmodium falciparum; Splenectomy; Travel | 2017 |
Molecular surveillance of Plasmodium falciparum drug resistance in the Republic of Congo: four and nine years after the introduction of artemisinin-based combination therapy.
Topics: Antimalarials; Artemisinins; Child; Child, Preschool; Cohort Studies; Democratic Republic of the Congo; Drug Resistance; Drug Therapy, Combination; Epidemiological Monitoring; Female; Gene Frequency; Humans; Infant; Malaria, Falciparum; Male; Plasmodium falciparum; Polymerase Chain Reaction; Selection, Genetic; Sequence Analysis, DNA | 2017 |
Watching the availability and use of rapid diagnostic tests (RDTs) and artemisinin-based combination therapy (ACT).
Topics: Antimalarials; Artemisinins; Diagnostic Tests, Routine; Drug Therapy, Combination; Health Services Accessibility; Humans; Malaria, Falciparum; Plasmodium falciparum | 2017 |
Absence of association between polymorphisms in the K13 gene and the presence of Plasmodium falciparum parasites at day 3 after treatment with artemisinin derivatives in Senegal.
Topics: Animals; Antimalarials; Artemisinins; Humans; Malaria, Falciparum; Mutation, Missense; Plasmodium falciparum; Point Mutation; Polymorphism, Genetic; Protozoan Proteins; Senegal; Sequence Analysis, DNA; Time Factors; Treatment Outcome | 2017 |
A Variant PfCRT Isoform Can Contribute to
Topics: Antimalarials; Artemisinins; Cambodia; Drug Resistance; Gene Editing; Humans; Lethal Dose 50; Malaria, Falciparum; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Mutation; Plasmodium falciparum; Protein Isoforms; Protozoan Proteins; Quinolines | 2017 |
Polymorphisms in pfdhfr and pfdhps genes after five years of artemisinin combination therapy (ACT) implementation from urban Kolkata, India.
Topics: Adult; Antimalarials; Artemisinins; Child; Cities; Dihydropteroate Synthase; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Gene Expression; Genotype; Humans; India; Malaria, Falciparum; Male; Mutation; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Pyrimethamine; Retrospective Studies; Sulfadoxine; Tetrahydrofolate Dehydrogenase | 2017 |
The Plasmodium PI(4)K inhibitor KDU691 selectively inhibits dihydroartemisinin-pretreated Plasmodium falciparum ring-stage parasites.
Topics: Animals; Antimalarials; Artemisinins; Cell Cycle Checkpoints; Drug Resistance; Humans; Malaria, Falciparum; Plasmodium falciparum; Pyrazines | 2017 |
Investigation of the component in Artemisia annua L. leading to enhanced antiplasmodial potency of artemisinin via regulation of its metabolism.
Topics: Animals; Antimalarials; Area Under Curve; Artemisia annua; Artemisinins; Biological Availability; Drug Synergism; Flavonoids; Inhibitory Concentration 50; Malaria, Falciparum; Male; Mice; Mice, Inbred ICR; Plant Extracts; Plasmodium falciparum; Rats; Rats, Wistar | 2017 |
[Elimination in South-East Asia? The role of antimalarial drugs].
Topics: Antimalarials; Artemether; Artemisinins; Asia, Southeastern; Disease Eradication; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Quinolines | 2016 |
Haemoglobin changes and risk of anaemia following treatment for uncomplicated falciparum malaria in sub-Saharan Africa.
Topics: Adolescent; Africa South of the Sahara; Anemia; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Therapy, Combination; Female; Hemoglobins; Humans; Infant; Malaria; Malaria, Falciparum; Male; Parasitemia; Risk Factors | 2017 |
Knockout of the peroxiredoxin 5 homologue PFAOP does not affect the artemisinin susceptibility of Plasmodium falciparum.
Topics: Artemisinins; Chromosome Mapping; Gene Expression; Gene Knockout Techniques; Humans; Malaria, Falciparum; Parasitic Sensitivity Tests; Peroxiredoxins; Plasmodium falciparum; Quantitative Trait Loci | 2017 |
Molecular Epidemiology of Malaria in Cameroon and Côte d'Ivoire. XXXI. Kelch 13 Propeller Sequences in
Topics: Antimalarials; Artemisinins; Cameroon; Cote d'Ivoire; Gene Expression Regulation; Humans; Malaria, Falciparum; Molecular Epidemiology; Plasmodium falciparum; Protozoan Proteins; Time Factors | 2017 |
A mechanistic model quantifies artemisinin-induced parasite growth retardation in blood-stage Plasmodium falciparum infection.
Topics: Animals; Anti-Infective Agents; Artemisinins; Life Cycle Stages; Malaria, Falciparum; Parasites; Plasmodium falciparum | 2017 |
Plasmodium falciparum in vitro continuous culture conditions: A comparison of parasite susceptibility and tolerance to anti-malarial drugs throughout the asexual intra-erythrocytic life cycle.
Topics: Antimalarials; Artemisinins; Culture Media; Erythrocytes; Ethanolamines; Fluorenes; Humans; Life Cycle Stages; Lumefantrine; Malaria, Falciparum; Oxygen; Parasitic Sensitivity Tests; Parasitology; Plasmodium falciparum | 2017 |
Challenges to replace ACT as first-line drug.
Topics: Antimalarials; Artemisinins; Asia; Communicable Disease Control; Drug Resistance; Drug Therapy, Combination; Malaria, Falciparum; Plasmodium falciparum | 2017 |
Polymorphisms of Plasmodium falciparum k13-propeller gene among migrant workers returning to Henan Province, China from Africa.
Topics: Adolescent; Adult; Africa, Western; Aged; Angola; Antimalarials; Artemisinins; China; Drug Resistance, Microbial; Female; Genotype; Humans; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Point Mutation; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Protozoan Proteins; South Africa; Transients and Migrants; Young Adult | 2017 |
Clinical and molecular surveillance of artemisinin resistant falciparum malaria in Myanmar (2009-2013).
Topics: Antimalarials; Artemisinins; Biomarkers; Drug Resistance; Malaria, Falciparum; Myanmar; Plasmodium falciparum; Protozoan Proteins | 2017 |
Molecular analysis demonstrates high prevalence of chloroquine resistance but no evidence of artemisinin resistance in Plasmodium falciparum in the Chittagong Hill Tracts of Bangladesh.
Topics: Antimalarials; Artemisinins; ATP-Binding Cassette Transporters; Bangladesh; Chloroquine; Drug Resistance; Humans; Malaria, Falciparum; Membrane Transport Proteins; Plasmodium falciparum; Protozoan Proteins; Sequence Analysis, DNA | 2017 |
Plasmodium falciparum HRP2 ELISA for analysis of dried blood spot samples in rural Zambia.
Topics: Antigens, Protozoan; Artemisinins; Biomarkers; Child, Preschool; Diagnostic Tests, Routine; Enzyme-Linked Immunosorbent Assay; Humans; Malaria, Falciparum; Microscopy; Plasmodium falciparum; Protozoan Proteins; Sensitivity and Specificity; Zambia | 2017 |
Partner-Drug Resistance and Population Substructuring of Artemisinin-Resistant Plasmodium falciparum in Cambodia.
Topics: Adult; Antipruritics; Artemisinins; Cambodia; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Phylogeny; Plasmodium falciparum; Protozoan Proteins; Quinolines; Treatment Failure | 2017 |
Prevalence of K13 mutation and Day-3 positive parasitaemia in artemisinin-resistant malaria endemic area of Cambodia: a cross-sectional study.
Topics: Antimalarials; Artemisinins; Cambodia; Cross-Sectional Studies; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Mutation; Parasitemia; Plasmodium falciparum; Prevalence; Protozoan Proteins | 2017 |
Declining Transmission and Immunity to Malaria and Emerging Artemisinin Resistance in Thailand: A Longitudinal Study.
Topics: Adolescent; Adult; Antibodies, Protozoan; Antigens, Protozoan; Antimalarials; Artemisinins; Child; Child, Preschool; DNA, Protozoan; Drug Resistance; Female; Humans; Linear Models; Longitudinal Studies; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Retrospective Studies; Thailand; Young Adult | 2017 |
Impact of Intermittent Preventive Treatment During Pregnancy on Plasmodium falciparum Drug Resistance-Mediating Polymorphisms in Uganda.
Topics: Antimalarials; Artemisinins; Drug Combinations; Drug Resistance; Female; Humans; Malaria, Falciparum; Plasmodium falciparum; Polymorphism, Genetic; Pregnancy; Pyrimethamine; Quinolines; Sulfadoxine | 2017 |
Drug-resistant malaria advances in Mekong.
Topics: Antimalarials; Artemisinins; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Plasmodium falciparum; Quinolines; Vietnam; World Health Organization | 2017 |
Enhanced antimalalarial activity of a prolonged release in situ gel of arteether-lumefantrine in a murine model.
Topics: Animals; Antimalarials; Artemisinins; Chemistry, Pharmaceutical; Delayed-Action Preparations; Disease Models, Animal; Drug Therapy, Combination; Ethanolamines; Fluorenes; Gels; Lumefantrine; Malaria, Falciparum; Male; Mice; Polymers | 2018 |
Cellular mechanisms of action and resistance of Plasmodium falciparum to artemisinin.
Topics: Antimalarials; Antioxidants; Artemisinins; Artesunate; Drug Resistance; Hemeproteins; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Polymorphism, Genetic; Thailand | 2017 |
Antimalarial activity of Malaria Box Compounds against Plasmodium falciparum clinical isolates.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Evaluation, Preclinical; Drug Resistance; Erythrocytes; Ghana; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum | 2017 |
The US President's Malaria Initiative, Plasmodium falciparum transmission and mortality: A modelling study.
Topics: Artemisinins; Female; Humans; Insecticides; Malaria, Falciparum; Models, Biological; Mosquito Nets; Plasmodium falciparum; Treatment Outcome | 2017 |
Plasmodium falciparum Kelch 13 mutations and treatment response in patients in Hpa-Pun District, Northern Kayin State, Myanmar.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Middle Aged; Mutation; Myanmar; Phenotype; Plasmodium falciparum; Polymorphism, Genetic; Prevalence; Protozoan Proteins; Young Adult | 2017 |
Plasmodium falciparum Recrudescence Two Years after Treatment of an Uncomplicated Infection without Return to an Area Where Malaria Is Endemic.
Topics: Adult; Antimalarials; Artemisinins; Female; France; Genetic Variation; Humans; Malaria, Falciparum; Plasmodium falciparum; Pregnancy; Recurrence; Travel | 2018 |
Antifolate drug resistance: Novel mutations and haplotype distribution in
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Child, Preschool; Contraindications, Drug; Dihydropteroate Synthase; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Gene Expression; Haplotypes; Humans; India; Malaria, Falciparum; Male; Middle Aged; Mutation; Plasmodium falciparum; Protozoan Proteins; Pyrimethamine; Sulfadoxine; Tetrahydrofolate Dehydrogenase | 2017 |
Poor response to artesunate treatment in two patients with severe malaria on the Thai-Myanmar border.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Drug Resistance; Fatal Outcome; Humans; Malaria, Falciparum; Male; Myanmar; Plasmodium falciparum; Quinine; Thailand; Treatment Outcome | 2018 |
Severe post-artesunate delayed onset anaemia responding to corticotherapy: a case report.
Topics: Administration, Intravenous; Adrenal Cortex Hormones; Adult; Anemia, Hemolytic; Artemisinins; Artesunate; Coombs Test; Hemolysis; Humans; Malaria, Falciparum; Male; Parasitemia; Travel | 2018 |
Prevalence of molecular markers of artemisinin and lumefantrine resistance among patients with uncomplicated Plasmodium falciparum malaria in three provinces in Angola, 2015.
Topics: Angola; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Biomarkers; Drug Resistance; Humans; Lumefantrine; Malaria, Falciparum; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins | 2018 |
Artemisinin-Resistant Plasmodium falciparum with High Survival Rates, Uganda, 2014-2016.
Topics: Antimalarials; Artemisinins; Child, Preschool; Cross-Sectional Studies; Drug Resistance; Female; Genotype; History, 21st Century; Humans; Malaria, Falciparum; Male; Mutation; Phenotype; Plasmodium falciparum; Survival Rate; Uganda; Whole Genome Sequencing | 2018 |
Assessment of household ownership of bed nets in areas with and without artemisinin resistance containment measures in Myanmar.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Resistance; Family Characteristics; Female; Health Services Accessibility; Humans; Infant; Infant, Newborn; Insecticide-Treated Bednets; Malaria, Falciparum; Male; Middle Aged; Myanmar; Plasmodium falciparum; Pregnancy; Retrospective Studies; Young Adult | 2018 |
Molecular Markers of
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Cross-Sectional Studies; Drug Combinations; Drug Resistance; Female; Genetic Markers; Ghana; Haplotypes; Humans; Infant, Newborn; Malaria, Falciparum; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Mutation; Plasmodium falciparum; Polymorphism, Single Nucleotide; Pregnancy; Protozoan Proteins; Pyrimethamine; Sulfadoxine; Tetrahydrofolate Dehydrogenase | 2018 |
Plasmodium falciparum merozoite protein-1 genetic diversity and multiplicity of infection in isolates from Congolese children consulting in a pediatric hospital in Brazzaville.
Topics: Animals; Antimalarials; Artemisinins; Child; Child, Preschool; Cohort Studies; Congo; Female; Fever; Genetic Variation; Genotype; Hospitals, Pediatric; Humans; Infant; Malaria, Falciparum; Male; Merozoite Surface Protein 1; Plasmodium falciparum; Polymerase Chain Reaction; Prevalence; Referral and Consultation | 2018 |
Plasmodium falciparum Falcipain-2a Polymorphisms in Southeast Asia and Their Association With Artemisinin Resistance.
Topics: Antimalarials; Artemisinins; China; Cysteine Endopeptidases; DNA, Protozoan; Drug Resistance; Genetic Variation; Haplotypes; Humans; Malaria, Falciparum; Myanmar; Plasmodium falciparum; Sequence Analysis, DNA | 2018 |
Influential Parameters for the Analysis of Intracellular Parasite Metabolomics.
Topics: Animals; Antimalarials; Artemisinins; Culture Media; Erythrocytes; Genome, Protozoan; Host-Parasite Interactions; Intracellular Space; Malaria, Falciparum; Mass Spectrometry; Metabolome; Metabolomics; Plasmodium falciparum; Protozoan Proteins | 2018 |
Optimal control of malaria: combining vector interventions and drug therapies.
Topics: Antimalarials; Artemisinins; Communicable Disease Control; Drug Combinations; Humans; Malaria, Falciparum; Models, Theoretical; Mosquito Control; Mosquito Vectors; Plasmodium falciparum | 2018 |
A novel field-based molecular assay to detect validated artemisinin-resistant k13 mutants.
Topics: Artemisinins; Cambodia; Chad; Drug Resistance; Humans; Malaria, Falciparum; Mutation; Myanmar; Plasmodium falciparum; Population Surveillance; Protozoan Proteins | 2018 |
How to combat emerging artemisinin resistance: Lessons from "The Three Little Pigs".
Topics: Animals; Antimalarials; Artemisinins; Disease Models, Animal; Drug Resistance; Humans; Malaria, Falciparum; Plasmodium falciparum; Public Health; Swine | 2018 |
Uncovering the essential genes of the human malaria parasite
Topics: Animals; Antimalarials; Artemisinins; Conserved Sequence; Drug Resistance; Erythrocytes; Genes, Essential; Genes, Protozoan; Genetic Fitness; Humans; Malaria Vaccines; Malaria, Falciparum; Mutagenesis; Plasmodium falciparum; Reproduction, Asexual | 2018 |
Comparison of the Pharmacokinetics and Ex Vivo Antimalarial Activities of Artesunate-Amodiaquine and Artemisinin-Piperaquine in Healthy Volunteers for Preselection Malaria Therapy.
Topics: Amodiaquine; Antimalarials; Area Under Curve; Artemisinins; Biotransformation; Drug Administration Schedule; Drug Combinations; Half-Life; Healthy Volunteers; Humans; Malaria, Falciparum; Male; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Tablets; Young Adult | 2018 |
Resistance screening and trend analysis of imported falciparum malaria in NSW, Australia (2010 to 2016).
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Resistance; Female; Genome; Genotype; Geography; Haplotypes; Humans; Infant; Malaria, Falciparum; Male; Middle Aged; Mutation; New South Wales; Papua New Guinea; Plasmodium falciparum; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Protozoan Proteins; Risk | 2018 |
Large-scale Artemisinin-Piperaquine Mass Drug Administration With or Without Primaquine Dramatically Reduces Malaria in a Highly Endemic Region of Africa.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Child, Preschool; Comoros; DNA, Protozoan; Drug Therapy, Combination; Endemic Diseases; Female; Humans; Infant; Malaria, Falciparum; Male; Mass Drug Administration; Parasitemia; Plasmodium falciparum; Polymorphism, Genetic; Primaquine; Quinolines; Treatment Outcome; Young Adult | 2018 |
Reduction of malaria prevalence after introduction of artemisinin-combination-therapy in Mbeya Region, Tanzania: results from a cohort study with 6773 participants.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Combinations; Female; Humans; Infant; Infant, Newborn; Longitudinal Studies; Malaria, Falciparum; Male; Middle Aged; Prevalence; Tanzania; Young Adult | 2018 |
Absence of K13 Polymorphism in Plasmodium falciparum from Brazilian Areas Where the Parasite Is Endemic.
Topics: Artemisinins; Brazil; DNA, Protozoan; Humans; Malaria, Falciparum; Mutation; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins | 2018 |
Implications of population-level immunity for the emergence of artemisinin-resistant malaria: a mathematical model.
Topics: Africa; Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria, Falciparum; Models, Biological; Plasmodium falciparum | 2018 |
Fitness Loss under Amino Acid Starvation in Artemisinin-Resistant Plasmodium falciparum Isolates from Cambodia.
Topics: Amino Acids; Antimalarials; Artemisinins; Cambodia; Drug Resistance; Genetic Fitness; Genotype; Humans; Malaria, Falciparum; Phenotype; Plasmodium falciparum; Polymorphism, Single Nucleotide; Starvation | 2018 |
Multiple Novel Mutations in
Topics: Amino Acid Substitution; Antigens, Protozoan; Antimalarials; Artemisinins; Drug Resistance; Drug Therapy, Combination; Female; Gene Expression; Haplotypes; Humans; Malaria, Falciparum; Male; Membrane Transport Proteins; Merozoite Surface Protein 1; Molecular Epidemiology; Mutation; Plasmodium falciparum; Protozoan Proteins; Selection, Genetic; Severity of Illness Index; Tetrahydrofolate Dehydrogenase; Thailand | 2018 |
[Polymorphism Analysis of Plasmodium falciparum K13 Gene Kelch Domain Associated with Resistance to Artemisinin in Yunnan Province].
Topics: Antimalarials; Artemisinins; China; Drug Resistance; Humans; Kelch Repeat; Malaria, Falciparum; Mutation; Plasmodium falciparum; Polymerase Chain Reaction; Polymorphism, Genetic; Protozoan Proteins | 2016 |
Investigating the Efficacy of Triple Artemisinin-Based Combination Therapies for Treating Plasmodium falciparum Malaria Patients Using Mathematical Modeling.
Topics: Antimalarials; Artemisinins; Asia, Southeastern; Drug Therapy, Combination; Humans; Malaria, Falciparum; Mefloquine; Models, Theoretical; Plasmodium falciparum; Quinolines | 2018 |
Synthesis, antimalarial activities and cytotoxicities of amino-artemisinin-1,2-disubstituted ferrocene hybrids.
Topics: Antimalarials; Artemisinins; Cell Line, Tumor; Ferrous Compounds; HEK293 Cells; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Metallocenes; Plasmodium falciparum | 2018 |
No Plasmodium falciparum Chloroquine Resistance Transporter and Artemisinin Resistance Mutations, Haiti.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Resistance; Haiti; Humans; Infant; Malaria, Falciparum; Membrane Transport Proteins; Middle Aged; Mutation; Plasmodium falciparum; Protozoan Proteins; Surveys and Questionnaires; Young Adult | 2018 |
No polymorphisms in K13-propeller gene associated with artemisinin resistance in Plasmodium falciparum isolated from Brazzaville, Republic of Congo.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Child; Congo; Drug Resistance; Female; Genotype; Humans; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Young Adult | 2018 |
Molecular Evidence for
Topics: Adolescent; Adult; Aged; Alleles; Antimalarials; Artemisinins; Artesunate; Child; Dihydropteroate Synthase; Drug Combinations; Drug Resistance; Epidemiological Monitoring; Female; Gene Expression; Humans; India; Kelch Repeat; Lumefantrine; Malaria, Falciparum; Male; Middle Aged; Molecular Epidemiology; Multidrug Resistance-Associated Proteins; Mutation; Plasmodium falciparum; Protozoan Proteins; Pyrimethamine; Sulfadoxine; Tetrahydrofolate Dehydrogenase | 2018 |
Evidence of Artemisinin-Resistant Plasmodium falciparum Malaria in Eastern India.
Topics: Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria, Falciparum; Mutation; Parasite Load; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins | 2018 |
K13-propeller gene polymorphisms in Plasmodium falciparum parasite population: a systematic review protocol of burden and associated factors.
Topics: Africa; Animals; Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria, Falciparum; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Systematic Reviews as Topic | 2018 |
Artemisinin resistance phenotypes and K13 inheritance in a
Topics: Animals; Antimalarials; Aotidae; Artemisinins; Crosses, Genetic; Drug Resistance; Gene Expression Regulation; Malaria, Falciparum; Mutation; Plasmodium falciparum; Protozoan Proteins | 2018 |
Quantification of Free Ferriprotoporphyrin IX Heme and Hemozoin for Artemisinin Sensitive versus Delayed Clearance Phenotype Plasmodium falciparum Malarial Parasites.
Topics: Animals; Antimalarials; Artemisinins; Drug Resistance; Erythrocytes; Heme; Hemeproteins; Hemin; Humans; Malaria, Falciparum; Phenotype; Plasmodium falciparum | 2018 |
The origins of malaria artemisinin resistance defined by a genetic and transcriptomic background.
Topics: Antimalarials; Artemisinins; Chromosome Mapping; DNA, Protozoan; Drug Resistance; Farnesyltranstransferase; Gene Expression; Gene Regulatory Networks; Genes, Protozoan; Geography; Humans; Malaria, Falciparum; Molecular Epidemiology; Mutation; Plasmodium falciparum; Protozoan Proteins; Thioredoxins; Transcriptome | 2018 |
Optimal Treatments for Severe Malaria and the Threat Posed by Artemisinin Resistance.
Topics: Acute Disease; Antimalarials; Artemisinins; Artesunate; Drug Resistance; Humans; Malaria, Falciparum; Models, Biological; Parasitemia; Plasmodium falciparum; Treatment Outcome | 2019 |
Changing Molecular Markers of Antimalarial Drug Sensitivity across Uganda.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Aspartic Acid Endopeptidases; Child; Chloroquine; Drug Resistance; Folic Acid Antagonists; Humans; Lumefantrine; Malaria, Falciparum; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Quinolines; Uganda | 2019 |
Artemisinin Resistance and Stage Dependency of Parasite Clearance in Falciparum Malaria.
Topics: Antimalarials; Artemisinins; Drug Resistance; Drug Therapy, Combination; Genotype; Humans; Life Cycle Stages; Malaria, Falciparum; Mutation; Parasitemia; Plasmodium falciparum; Protozoan Proteins | 2019 |
Evaluation of the effects on the QT-interval of 4 artemisinin-based combination therapies with a correction-free and heart rate-free method.
Topics: Adolescent; Amodiaquine; Antimalarials; Arrhythmias, Cardiac; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Child, Preschool; Drug Combinations; Ethanolamines; Female; Fluorenes; Heart Rate; Humans; Long QT Syndrome; Malaria; Malaria, Falciparum; Male; Quinolines; Young Adult | 2019 |
Plasmodium falciparum malarial parasites from Brazil lack artemisinin resistance-associated mutations in the kelch13 gene.
Topics: Artemisinins; Drug Resistance; Genotype; Humans; Malaria, Falciparum; Mutation; Phenotype; Plasmodium falciparum; Protozoan Proteins | 2019 |
Plasmodium falciparum Clearance Is Pitting-Dependent With Artemisinin-Based Drugs but Pitting-Independent With Atovaquone-Proguanil or Mefloquine.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Atovaquone; Child; Drug Combinations; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Proguanil; Young Adult | 2019 |
Effect of artemisinin-piperaquine treatment on the electrocardiogram of malaria patients.
Topics: Adult; Antimalarials; Artemisinins; Drug Therapy, Combination; Electrocardiography; Female; Humans; Long QT Syndrome; Malaria, Falciparum; Male; Middle Aged; Quinolines; Retrospective Studies | 2019 |
An improved nucleic acid extraction method from dried blood spots for amplification of Plasmodium falciparum kelch13 for detection of artemisinin resistance.
Topics: Antimalarials; Artemisinins; Asia, Southeastern; Blood; Desiccation; DNA, Protozoan; Drug Resistance; Humans; Malaria, Falciparum; Plasmodium falciparum; Polymerase Chain Reaction; Protozoan Proteins; Sequence Analysis, DNA; Specimen Handling | 2019 |
Genomic structure and diversity of Plasmodium falciparum in Southeast Asia reveal recent parasite migration patterns.
Topics: Antimalarials; Artemisinins; Asia, Southeastern; Biodiversity; Drug Resistance; Epidemiological Monitoring; Genome, Protozoan; Genotype; Geography, Medical; Malaria, Falciparum; Plasmodium falciparum; Polymorphism, Single Nucleotide | 2019 |
Effects and Mechanism of Action of Artemisinin on Mitochondria of Plasmodium berghei.
Topics: Animals; Antimalarials; Artemisinins; Energy Metabolism; Malaria, Falciparum; Membrane Potentials; Mice; Mitochondria; Oxidative Stress; Plasmodium berghei; Reactive Oxygen Species; Superoxide Dismutase | 2020 |
Improving Methods for Analyzing Antimalarial Drug Efficacy Trials: Molecular Correction Based on Length-Polymorphic Markers
Topics: Algorithms; Antigens, Protozoan; Antimalarials; Artemisinins; Biomarkers; Clinical Trials as Topic; Gene Expression; Humans; Lumefantrine; Malaria, Falciparum; Mefloquine; Merozoite Surface Protein 1; Models, Statistical; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Restriction Fragment Length; Protozoan Proteins; Quinolines; Time Factors; Treatment Outcome | 2019 |
Geographic Plasmodium falciparum sarcoplasmic reticulum Ca2+ ATPase (PfSERCA) genotype diversity in India.
Topics: Antimalarials; Artemisinins; Calcium-Transporting ATPases; Child; Drug Resistance; Genotype; Haplotypes; Humans; India; Malaria, Falciparum; Mutation; Plasmodium falciparum; Sarcoplasmic Reticulum | 2020 |
Molecular Surveillance of Drug Resistance of Plasmodium falciparum Isolates Imported from Angola in Henan Province, China.
Topics: Amino Acid Substitution; Angola; Antimalarials; Artemisinins; China; Dihydropteroate Synthase; Drug Resistance; Epidemiological Monitoring; Gene Expression; Humans; Malaria, Falciparum; Membrane Transport Proteins; Molecular Epidemiology; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Tetrahydrofolate Dehydrogenase; Travel | 2019 |
High prevalence of asymptomatic malaria in a tribal population in eastern India.
Topics: Antimalarials; Artemisinins; Asymptomatic Infections; Base Sequence; Drug Combinations; Drug Resistance; Genotype; Humans; India; Malaria, Falciparum; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Polymorphism, Single Nucleotide; Population Groups; Prevalence; Protozoan Proteins; Pyrimethamine; Sequence Analysis, DNA; Sulfadoxine | 2013 |
Genetic diversity and lack of artemisinin selection signature on the Plasmodium falciparum ATP6 in the Greater Mekong Subregion.
Topics: Antimalarials; Artemisinins; Asia, Southeastern; Calcium-Transporting ATPases; DNA, Protozoan; Drug Resistance; Haplotypes; Humans; Malaria, Falciparum; Mutation; Phylogeography; Plasmodium falciparum; Polymorphism, Single Nucleotide; Selection, Genetic | 2013 |
High-level semi-synthetic production of the potent antimalarial artemisinin.
Topics: Antimalarials; Artemisinins; Biosynthetic Pathways; Biotechnology; Fermentation; Genetic Engineering; Malaria, Falciparum; Molecular Sequence Data; Saccharomyces cerevisiae; Singlet Oxygen | 2013 |
Genetic evaluation of the performance of malaria parasite clearance rate metrics.
Topics: Animals; Antimalarials; Artemisinins; Genotype; Humans; Malaria, Falciparum; Parasitemia; Plasmodium falciparum; Polymorphism, Single Nucleotide | 2013 |
High-throughput analysis of antimalarial susceptibility data by the WorldWide Antimalarial Resistance Network (WWARN) in vitro analysis and reporting tool.
Topics: Amodiaquine; Antimalarials; Artemisinins; Automation, Laboratory; Chloroquine; Drug Resistance; Drug Therapy, Combination; High-Throughput Screening Assays; Internet; Malaria, Falciparum; Mefloquine; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinine | 2013 |
Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia.
Topics: Antimalarials; Artemisinins; Cambodia; Chromosome Painting; Cluster Analysis; Drug Resistance; Founder Effect; Genes, Protozoan; Genetic Association Studies; Homozygote; Humans; Malaria, Falciparum; Models, Genetic; Plasmodium falciparum; Polymorphism, Single Nucleotide; Principal Component Analysis | 2013 |
Genome sequencing sheds light on emerging drug resistance in malaria parasites.
Topics: Antimalarials; Artemisinins; Genes, Protozoan; Humans; Malaria, Falciparum; Plasmodium falciparum | 2013 |
Artemisinin resistance in Plasmodium falciparum: what is it really?
Topics: Animals; Antimalarials; Artemisinins; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Plasmodium falciparum | 2013 |
Epidemiology: resistance mapping in malaria.
Topics: Animals; Antimalarials; Artemisinins; Drug Resistance; Genome, Protozoan; Humans; Malaria, Falciparum; Plasmodium falciparum | 2013 |
Definition of hyperparasitemia in severe falciparum malaria should be updated.
Topics: Anemia; Antimalarials; Artemisinins; Humans; Malaria, Falciparum; Parasitemia; Plasmodium falciparum; Severity of Illness Index | 2013 |
Artemisinin therapy and severe delayed haemolysis.
Topics: Adult; Anemia, Hemolytic; Antimalarials; Artemisinins; Hemolysis; Humans; Malaria, Falciparum; Male | 2013 |
Travellers as sentinels: Assaying the worldwide distribution of polymorphisms associated with artemisinin combination therapy resistance in Plasmodium falciparum using malaria cases imported into Scotland.
Topics: Antimalarials; Artemisinins; Asia; Drug Resistance; Malaria, Falciparum; Phylogeography; Plasmodium falciparum; Polymorphism, Single Nucleotide; Scotland; Sentinel Surveillance; Travel | 2013 |
Trends in antimalarial drug use in Africa.
Topics: Africa; Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Drug Resistance; Health Surveys; Humans; Malaria, Falciparum; Models, Statistical; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Time Factors | 2013 |
Health worker factors associated with prescribing of artemisinin combination therapy for uncomplicated malaria in rural Tanzania.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Attitude of Health Personnel; Child; Child, Preschool; Drug Prescriptions; Female; Guideline Adherence; Humans; Infant; Infant, Newborn; Malaria, Falciparum; Male; Middle Aged; Practice Patterns, Physicians'; Rural Population; Tanzania; Young Adult | 2013 |
Model system to define pharmacokinetic requirements for antimalarial drug efficacy.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Disease Models, Animal; Humans; Malaria, Falciparum; Mice; Mice, Inbred C57BL; Models, Biological; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Reproducibility of Results; Treatment Outcome | 2013 |
Evidence for pyronaridine as a highly effective partner drug for treatment of artemisinin-resistant malaria in a rodent model.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Artesunate; Drug Combinations; Drug Resistance; Female; Flow Cytometry; Malaria, Falciparum; Mefloquine; Mice; Naphthyridines | 2014 |
Optimal sampling designs for estimation of Plasmodium falciparum clearance rates in patients treated with artemisinin derivatives.
Topics: Africa; Artemisinins; Asia; Humans; Malaria, Falciparum; Parasite Load; Parasitemia; Plasmodium falciparum; Specimen Handling; Time Factors | 2013 |
Malaria: Resistance nailed.
Topics: Animals; Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria, Falciparum; Plasmodium falciparum; Protozoan Proteins | 2014 |
A molecular marker of artemisinin-resistant Plasmodium falciparum malaria.
Topics: Alleles; Animals; Antimalarials; Artemisinins; Blood Cells; Cambodia; Drug Resistance; Genetic Markers; Half-Life; Humans; Malaria, Falciparum; Mutation; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protein Structure, Tertiary; Protozoan Proteins; Time Factors | 2014 |
Vector control to eliminate artemisinin resistant malaria in the Greater Mekong subregion.
Topics: Animals; Anopheles; Antimalarials; Artemisinins; Asia, Southeastern; Disease Vectors; Drug Resistance; Humans; Malaria, Falciparum; Mosquito Control; Plasmodium falciparum | 2014 |
Prevailing Plasmodium falciparum dihydrofolate reductase 108-asparagine in Hodeidah, Yemen: a questionable sulfadoxine-pyrimethamine partner within the artemisinin-based combination therapy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Asparagine; Child; Child, Preschool; Cross-Sectional Studies; DNA, Protozoan; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Gene Frequency; Humans; Infant; Infant, Newborn; Malaria, Falciparum; Male; Middle Aged; Mutation, Missense; Plasmodium falciparum; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Pyrimethamine; Sulfadoxine; Tetrahydrofolate Dehydrogenase; Yemen; Young Adult | 2014 |
Detecting adenosine triphosphatase 6 (pfATP6) point mutations that may be associated with Plasmodium falciparum resistance to artemisinin: prevalence at baseline, before policy change in Uganda.
Topics: Anti-Infective Agents; Artemether; Artemisinins; Calcium-Transporting ATPases; Drug Resistance, Microbial; Drug Therapy, Combination; Ethanolamines; Fluorenes; Genotype; Humans; Lumefantrine; Malaria, Falciparum; Point Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Prevalence; Sequence Analysis, DNA; Uganda | 2011 |
Communicating the AMFm message: exploring the effect of communication and training interventions on private for-profit provider awareness and knowledge related to a multi-country anti-malarial subsidy intervention.
Topics: Africa South of the Sahara; Antimalarials; Artemisinins; Communication; Drug Combinations; Health Knowledge, Attitudes, Practice; Health Services Accessibility; Humans; Malaria, Falciparum; Private Sector | 2014 |
Were medicine quality and pharmaceutical management contributing factors in diminishing artemisinin efficacy in Guyana and Suriname?
Topics: Antimalarials; Artemisinins; Drug Resistance; Drug Utilization; Guyana; Humans; Malaria, Falciparum; Plasmodium falciparum; Suriname; Treatment Outcome | 2014 |
Artemisinin combination therapies and malaria parasite drug resistance: the game is afoot.
Topics: Artemisinins; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Plasmodium falciparum; Polymorphism, Genetic | 2014 |
Comparative impacts over 5 years of artemisinin-based combination therapies on Plasmodium falciparum polymorphisms that modulate drug sensitivity in Ugandan children.
Topics: Alleles; Artemisinins; Child, Preschool; Drug Resistance; Female; Humans; Infant; Malaria, Falciparum; Male; Plasmodium falciparum; Polymorphism, Genetic; Uganda | 2014 |
Laboratory detection of artemisinin-resistant Plasmodium falciparum.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Drug Resistance; Half-Life; Malaria, Falciparum; Parasitic Sensitivity Tests; Phenotype; Plasmodium falciparum | 2014 |
Competition between Plasmodium falciparum strains in clinical infections during in vitro culture adaptation.
Topics: Alleles; Antigens, Protozoan; Antimalarials; Artemisinins; DNA, Protozoan; Drug Resistance; Genetic Variation; Genotype; Humans; Malaria, Falciparum; Merozoite Surface Protein 1; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Protozoan Proteins; Quinolines; Tetrahydrofolate Dehydrogenase | 2014 |
Comparison of an assumed versus measured leucocyte count in parasite density calculations in Papua New Guinean children with uncomplicated malaria.
Topics: Antimalarials; Artemisinins; Child, Preschool; Drug Combinations; Female; Humans; Leukocyte Count; Malaria, Falciparum; Malaria, Vivax; Male; Microscopy; Papua New Guinea; Parasite Load; Plasmodium falciparum; Plasmodium vivax | 2014 |
Quality of antimalarial drugs and antibiotics in Papua New Guinea: a survey of the health facility supply chain.
Topics: Amodiaquine; Amoxicillin; Antimalarials; Artemether; Artemisinins; Biosimilar Pharmaceuticals; Chloroquine; Drug Resistance; Health Facilities; Humans; Malaria, Falciparum; Malaria, Vivax; Papua New Guinea; Primaquine; Quality Control; Quinine | 2014 |
Plasmodium falciparum founder populations in western Cambodia have reduced artemisinin sensitivity in vitro.
Topics: Alleles; Antimalarials; Artemisinins; Cambodia; Drug Resistance; Founder Effect; Half-Life; Humans; Life Cycle Stages; Malaria, Falciparum; Mutation; Parasitic Sensitivity Tests; Plasmodium falciparum | 2014 |
Directional selection at the pfmdr1, pfcrt, pfubp1, and pfap2mu loci of Plasmodium falciparum in Kenyan children treated with ACT.
Topics: Antimalarials; Artemisinins; Cambodia; Child; Child, Preschool; Drug Resistance; Drug Therapy, Combination; Female; Genotype; Humans; Infant; Kenya; Malaria, Falciparum; Male; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Protozoan Proteins; Selection, Genetic | 2014 |
[Case of severe tropical malaria with a suspicion of hemolytic anemia due to a artemisinin derivative].
Topics: Anemia, Hemolytic; Anti-Infective Agents; Artemisinins; Humans; Malaria, Falciparum; Male; Young Adult | 2014 |
Evaluation of community-based systems for the surveillance of day three-positive Plasmodium falciparum cases in Western Cambodia.
Topics: Artemisinins; Attitude of Health Personnel; Cambodia; Cluster Analysis; Community Health Workers; Community-Based Participatory Research; Comorbidity; Drug Resistance; Feasibility Studies; Health Personnel; House Calls; Humans; Interviews as Topic; Malaria, Falciparum; Malaria, Vivax; Microscopy; Parasitemia; Parasitology; Pilot Projects; Plasmodium falciparum; Population Surveillance; Program Evaluation; Qualitative Research; Remuneration; Specimen Handling; Time Factors; Transportation | 2014 |
Molecular surveillance for artemisinin resistance in Africa.
Topics: Adolescent; Africa; Artemisinins; Child; Child, Preschool; Drug Resistance; Epidemiological Monitoring; Genetic Markers; Genotyping Techniques; Humans; Infant; Malaria, Falciparum; Plasmodium falciparum; Young Adult | 2014 |
The challenge of artemisinin resistance can only be met by eliminating Plasmodium falciparum malaria across the Greater Mekong subregion.
Topics: Antimalarials; Artemisinins; Asia, Southeastern; Drug Resistance; Humans; Malaria, Falciparum; Plasmodium falciparum | 2014 |
Inhibition of metalloproteinase-9 secretion and gene expression by artemisinin derivatives.
Topics: Artemisinins; Artesunate; Cytokines; Gene Expression Regulation; Humans; Inflammation Mediators; Malaria, Cerebral; Malaria, Falciparum; Matrix Metalloproteinase 9; Monocytes; Plasmodium falciparum; Polymerase Chain Reaction; RNA, Messenger | 2014 |
Absence of putative artemisinin resistance mutations among Plasmodium falciparum in Sub-Saharan Africa: a molecular epidemiologic study.
Topics: Adult; Africa South of the Sahara; Antimalarials; Artemisinins; Child; Child, Preschool; Female; Gene Frequency; Genotype; High-Throughput Nucleotide Sequencing; Humans; Malaria, Falciparum; Male; Molecular Epidemiology; Mutation; Plasmodium falciparum; Polymorphism, Genetic; Pregnancy; Prevalence | 2015 |
Artemisinin resistance: the more we know, the more complicated it appears.
Topics: Antimalarials; Artemisinins; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Mutation; Plasmodium falciparum; Pregnancy | 2015 |
Molecular evidence of increased resistance to anti-folate drugs in Plasmodium falciparum in North-East India: a signal for potential failure of artemisinin plus sulphadoxine-pyrimethamine combination therapy.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Codon; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Haplotypes; Humans; India; Malaria, Falciparum; Male; Membrane Transport Proteins; Middle Aged; Multidrug Resistance-Associated Proteins; Mutation; Plasmodium falciparum; Protozoan Proteins; Pyrimethamine; Sulfadoxine | 2014 |
Monitoring parasite diversity for malaria elimination in sub-Saharan Africa.
Topics: Africa South of the Sahara; Animals; Anopheles; Antimalarials; Artemisinins; Disease Eradication; Drug Resistance; Epidemiological Monitoring; Genetic Variation; Humans; Malaria, Falciparum; Plasmodium falciparum | 2014 |
Complex polymorphisms in the Plasmodium falciparum multidrug resistance protein 2 gene and its contribution to antimalarial response.
Topics: Amino Acid Sequence; Antimalarials; Artemisinins; Biological Transport; Chloroquine; Chromosomes; Drug Resistance, Multiple; Erythrocytes; Humans; INDEL Mutation; Malaria, Falciparum; Mefloquine; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Single Nucleotide; Quinolines; Thailand | 2014 |
Plasmodium prevalence and artemisinin-resistant falciparum malaria in Preah Vihear Province, Cambodia: a cross-sectional population-based study.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Cambodia; Child; Child, Preschool; Cross-Sectional Studies; Drug Resistance; Female; Humans; Infant; Infant, Newborn; Malaria, Falciparum; Male; Middle Aged; Mutation; Plasmodium falciparum; Prevalence; Young Adult | 2014 |
Genetic mutations in pfcrt and pfmdr1 at the time of artemisinin combination therapy introduction in South Pacific islands of Vanuatu and Solomon Islands.
Topics: Antimalarials; Artemisinins; Child; Child, Preschool; Dried Blood Spot Testing; Drug Therapy, Combination; Haplotypes; Humans; Malaria, Falciparum; Melanesia; Membrane Transport Proteins; Microsatellite Repeats; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Prevalence; Protozoan Proteins; Vanuatu | 2014 |
A marked decline in the incidence of malaria in a remote region of Malaita, Solomon Islands, 2008 to 2013.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Child; Child, Preschool; Female; Hospitals; Humans; Incidence; Infant; Infant, Newborn; Malaria, Falciparum; Malaria, Vivax; Male; Melanesia; Middle Aged; Plasmodium falciparum; Plasmodium vivax; Population Surveillance; Seasons; Social Capital; Young Adult | 2014 |
K13-propeller polymorphisms in Plasmodium falciparum parasites from sub-Saharan Africa.
Topics: Alleles; Antimalarials; Artemisinins; Asia, Southeastern; Drug Resistance; Gene Frequency; Humans; Malaria, Falciparum; Mutation; Plasmodium falciparum; Polymorphism, Single Nucleotide | 2015 |
Development of a novel malarial vaccine design: a hypothetical approach.
Topics: Adjuvants, Immunologic; Animals; Artemisinins; Benzopyrans; Catechols; Cell Movement; Chlorates; Drug Design; Drug Therapy, Combination; Female; Humans; Immunotherapy, Active; Malaria Vaccines; Malaria, Falciparum; Plasmodium falciparum; Protease Inhibitors; Sporozoites | 2014 |
Artemisinin resistance--modelling the potential human and economic costs.
Topics: Antimalarials; Artemisinins; Artesunate; Drug Resistance; Drug Therapy, Combination; Health Care Costs; Humans; Malaria, Falciparum; Quinine | 2014 |
Contrasting benefits of different artemisinin combination therapies as first-line malaria treatments using model-based cost-effectiveness analysis.
Topics: Africa; Antimalarials; Artemisinins; Cost-Benefit Analysis; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Models, Theoretical; Quinolines; Seasons | 2014 |
Global distribution of polymorphisms associated with delayed Plasmodium falciparum parasite clearance following artemisinin treatment: genotyping of archive blood samples.
Topics: Africa; Antimalarials; Artemisinins; Blood; Cambodia; Drug Resistance; Drug Therapy, Combination; Genotype; Humans; Linkage Disequilibrium; Malaria, Falciparum; Mutation; Plasmodium falciparum; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Sequence Analysis, DNA; South America; Thailand | 2015 |
Subtle changes in Plasmodium falciparum infection complexity following enhanced intervention in Malawi.
Topics: Artemisinins; Child, Preschool; Genetic Variation; Genotype; Humans; Infant; Infant, Newborn; Insecticide-Treated Bednets; Malaria, Falciparum; Malawi; Mosquito Control; Plasmodium falciparum; Polymorphism, Single Nucleotide; Population Density | 2015 |
Drug resistance. K13-propeller mutations confer artemisinin resistance in Plasmodium falciparum clinical isolates.
Topics: Amino Acid Sequence; Antimalarials; Artemisinins; Cambodia; Drug Resistance; Genetic Loci; Humans; Malaria, Falciparum; Molecular Sequence Data; Mutation; Plasmodium falciparum; Protein Structure, Tertiary; Protozoan Proteins | 2015 |
Drug resistance. Population transcriptomics of human malaria parasites reveals the mechanism of artemisinin resistance.
Topics: Animals; Antimalarials; Artemisinins; Chaperonin Containing TCP-1; Drug Resistance; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum; Transcriptome; Unfolded Protein Response | 2015 |
Infectious diseases. The genetics of resistant malaria.
Topics: Antimalarials; Artemisinins; Drug Resistance; Drug Therapy, Combination; Genes, Protozoan; Humans; Malaria, Falciparum; Mutation; Plasmodium falciparum; Protozoan Proteins | 2014 |
Plasmodium falciparum field isolates from areas of repeated emergence of drug resistant malaria show no evidence of hypermutator phenotype.
Topics: Antimalarials; Artemisinins; Asia, Southeastern; DNA, Protozoan; Drug Resistance; Humans; Malaria, Falciparum; Mutation Rate; Phenotype; Plasmodium falciparum; Sequence Analysis, DNA | 2015 |
Pooled sequencing and rare variant association tests for identifying the determinants of emerging drug resistance in malaria parasites.
Topics: Antimalarials; Artemisinins; Base Sequence; Drug Resistance; Genetic Association Studies; Genome; Humans; Malaria, Falciparum; Molecular Sequence Data; Plasmodium falciparum; Polymorphism, Single Nucleotide; Sequence Analysis, DNA | 2015 |
The MSPDBL2 codon 591 polymorphism is associated with lumefantrine in vitro drug responses in Plasmodium falciparum isolates from Kilifi, Kenya.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Codon; Drug Combinations; Drug Resistance; Ethanolamines; Fluorenes; Humans; Kenya; Lumefantrine; Malaria, Falciparum; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins | 2015 |
Molecular assessment of artemisinin resistance markers, polymorphisms in the k13 propeller, and a multidrug-resistance gene in the eastern and western border areas of Myanmar.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Child, Preschool; DNA, Protozoan; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Molecular Sequence Data; Mutation, Missense; Myanmar; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Sequence Analysis, DNA; Young Adult | 2015 |
Detection of point mutation in Plasmodium falciparum ATPase6 gene associated with artemisinin resistance from Assam and Arunachal Pradesh.
Topics: Antimalarials; Artemisinins; DNA, Protozoan; Drug Resistance; Female; Gene Frequency; Humans; India; Malaria, Falciparum; Male; Mitochondrial Proton-Translocating ATPases; Plasmodium falciparum; Point Mutation; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Sequence Analysis, DNA | 2014 |
Molecular modelling based target identification for endo-peroxides class of antimalarials.
Topics: Amino Acid Sequence; Antimalarials; Artemisinins; Calcium-Transporting ATPases; Drug Design; Heme; Heterocyclic Compounds; Humans; Malaria, Falciparum; Models, Molecular; Molecular Docking Simulation; Molecular Sequence Data; Plasmodium falciparum; Sequence Alignment | 2015 |
Plasmodium falciparum genotype diversity in artemisinin derivatives treatment failure patients along the Thai-Myanmar border.
Topics: Adult; Antigens, Protozoan; Antimalarials; Artemisinins; Female; Gene Frequency; Genetic Variation; Genotype; Humans; Malaria, Falciparum; Male; Merozoite Surface Protein 1; Myanmar; Plasmodium falciparum; Polymerase Chain Reaction; Protozoan Proteins; Thailand; Treatment Failure | 2014 |
Infectious diseases. Understanding artemisinin resistance.
Topics: Animals; Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum; Protozoan Proteins; Unfolded Protein Response | 2015 |
Comparing the impact of artemisinin-based combination therapies on malaria transmission in sub-Saharan Africa.
Topics: Africa South of the Sahara; Artemisinins; Drug Therapy, Combination; Humans; Malaria, Falciparum; Models, Biological; Uncertainty | 2015 |
Artemisinin resistance-associated polymorphisms at the K13-propeller locus are absent in Plasmodium falciparum isolates from Haiti.
Topics: Antimalarials; Artemisinins; Drug Resistance; Haiti; Humans; Malaria, Falciparum; Plasmodium falciparum; Polymorphism, Genetic | 2015 |
Analysis of major genome loci underlying artemisinin resistance and pfmdr1 copy number in pre- and post-ACTs in western Kenya.
Topics: Alleles; Antimalarials; Artemisinins; Gene Dosage; Gene Frequency; Genetic Loci; Humans; Inhibitory Concentration 50; Kenya; Malaria, Falciparum; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Polymorphism, Genetic; Polymorphism, Single Nucleotide | 2015 |
Novel mutations in K13 propeller gene of artemisinin-resistant Plasmodium falciparum.
Topics: Anti-Infective Agents; Artemisinins; Cross-Sectional Studies; Drug Resistance; Geography; Humans; Kenya; Malaria, Falciparum; Mutation; Parasitic Sensitivity Tests; Plasmodium falciparum; Protozoan Proteins | 2015 |
Towards real-time monitoring of artemisinin resistance.
Topics: Antimalarials; Artemisinins; Drug Resistance; Malaria, Falciparum; Plasmodium falciparum | 2015 |
Spread of artemisinin-resistant Plasmodium falciparum in Myanmar: a cross-sectional survey of the K13 molecular marker.
Topics: Antimalarials; Artemisinins; Bangladesh; Cross-Sectional Studies; DNA, Protozoan; Drug Resistance; Genetic Markers; Genotype; Malaria, Falciparum; Mutation; Myanmar; Phylogeography; Plasmodium falciparum; Prevalence; Sequence Analysis, DNA; Thailand | 2015 |
Impact of Artemisinin-Based Combination Therapy on Falciparum Malaria in Urban Kolkata: A Clinic-Based Report.
Topics: Artemisinins; Drug Therapy, Combination; Humans; Incidence; India; Malaria, Falciparum; Malaria, Vivax; Retrospective Studies; Treatment Outcome; Urban Population | 2015 |
Selection and spread of artemisinin-resistant alleles in Thailand prior to the global artemisinin resistance containment campaign.
Topics: Alleles; Anti-Infective Agents; Antigens, Bacterial; Antigens, Surface; Artemisinins; Containment of Biohazards; Drug Resistance, Microbial; Epidemiological Monitoring; Genotype; Humans; Malaria, Falciparum; Molecular Sequence Data; Mutation; Plasmodium falciparum; Polymerase Chain Reaction; Thailand | 2015 |
A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria.
Topics: Antimalarials; Artemisinins; Drug Resistance; Genome-Wide Association Study; Malaria, Falciparum; Models, Molecular; Mutation; Phosphatidylinositol 3-Kinase; Phosphatidylinositol Phosphates; Phosphoinositide-3 Kinase Inhibitors; Plasmodium falciparum; Protozoan Proteins | 2015 |
Microbiology: Malaria runs rings round artemisinin.
Topics: Antimalarials; Artemisinins; Drug Resistance; Malaria, Falciparum; Phosphoinositide-3 Kinase Inhibitors; Plasmodium falciparum | 2015 |
Observing in real time the evolution of artemisinin resistance in Plasmodium falciparum.
Topics: Antimalarials; Artemisinins; Asia, Southeastern; Biological Evolution; Genotype; Malaria, Falciparum; Plasmodium falciparum | 2015 |
A Single Mutation in K13 Predominates in Southern China and Is Associated With Delayed Clearance of Plasmodium falciparum Following Artemisinin Treatment.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Child; Child, Preschool; China; Drug Tolerance; Female; Genotype; Humans; Infant; Malaria, Falciparum; Male; Middle Aged; Mutation, Missense; Plasmodium falciparum; Prospective Studies; Protozoan Proteins; Sequence Analysis, DNA; Treatment Outcome; Young Adult | 2015 |
Plasmodium falciparum population structure in Sudan post artemisinin-based combination therapy.
Topics: Antimalarials; Artemisinins; Drug Therapy, Combination; Genetic Variation; Genotype; Haplotypes; Humans; Linkage Disequilibrium; Malaria, Falciparum; Microsatellite Repeats; Plasmodium falciparum; Sudan; Trinucleotide Repeats | 2015 |
Defining the in vivo phenotype of artemisinin-resistant falciparum malaria: a modelling approach.
Topics: Antimalarials; Artemisinins; Artesunate; Cambodia; Drug Resistance; Humans; Life Cycle Stages; Malaria, Falciparum; Myanmar; Parasite Load; Parasitemia; Phenotype; Phylogeny; Plasmodium falciparum; Reference Values; Thailand | 2015 |
Keeping ahead of the resistance curve: product bundling to conserve artemisinin-based combination therapy.
Topics: Antimalarials; Artemisinins; Humans; Malaria, Falciparum; Mass Screening | 2015 |
Gametocyte Clearance Kinetics Determined by Quantitative Magnetic Fractionation in Melanesian Children with Uncomplicated Malaria Treated with Artemisinin Combination Therapy.
Topics: Antimalarials; Artemether; Artemisinins; Child, Preschool; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Half-Life; Humans; Kinetics; Lumefantrine; Malaria, Falciparum; Malaria, Vivax; Male; Naphthoquinones; Plasmodium falciparum | 2015 |
Ex Vivo Drug Susceptibility Testing and Molecular Profiling of Clinical Plasmodium falciparum Isolates from Cambodia from 2008 to 2013 Suggest Emerging Piperaquine Resistance.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Cambodia; Chloroquine; Drug Resistance; Female; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Male; Mefloquine; Membrane Transport Proteins; Middle Aged; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Young Adult | 2015 |
Quality of artemisinin-based combination formulations for malaria treatment: prevalence and risk factors for poor quality medicines in public facilities and private sector drug outlets in Enugu, Nigeria.
Topics: Antimalarials; Artemisinins; Artesunate; Chromatography, High Pressure Liquid; Humans; Malaria, Falciparum; Nigeria; Pharmacies; Private Sector; Public Facilities; Quality Control; Risk Factors; Tablets | 2015 |
Antimalarial Effect of 3-Methoxy-1,2-Dioxetanes on the Erythrocytic Cycle of Plasmodium falciparum.
Topics: Animals; Antimalarials; Artemisinins; Drug Design; Drug Evaluation, Preclinical; Erythrocytes; Hemolysis; Humans; In Vitro Techniques; Malaria, Falciparum; Peroxides; Plasmodium falciparum | 2015 |
Slow Clearance of Plasmodium falciparum in Severe Pediatric Malaria, Uganda, 2011-2013.
Topics: Antimalarials; Artemisinins; Child; Child, Preschool; Drug Resistance; Female; Genes, Protozoan; Humans; Infant; Malaria, Falciparum; Male; Plasmodium falciparum; Polymorphism, Single Nucleotide; Sequence Analysis, DNA; Uganda | 2015 |
Altering Antimalarial Drug Regimens May Dramatically Enhance and Restore Drug Effectiveness.
Topics: Adult; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Drug Dosage Calculations; Ethanolamines; Female; Fluorenes; Humans; Malaria, Falciparum; Male; Models, Statistical; Parasitic Sensitivity Tests; Plasmodium falciparum; Pregnancy; Treatment Outcome | 2015 |
A Case of Complicated Falciparum Malaria with Treatment Failure to Artemisinin Combination Therapy.
Topics: Adolescent; Antimalarials; Artemisinins; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Male; Treatment Failure | 2014 |
Is the A578S Single-Nucleotide Polymorphism in K13-propeller a Marker of Emerging Resistance to Artemisinin Among Plasmodium falciparum in Africa?
Topics: Africa; Antimalarials; Artemisinins; Drug Resistance; Genetic Markers; Humans; Malaria, Falciparum; Plasmodium falciparum; Polymorphism, Single Nucleotide | 2016 |
Artemisinin resistance at the China-Myanmar border and association with mutations in the K13 propeller gene.
Topics: Artemisinins; China; Drug Resistance, Multiple; Genotype; Malaria, Falciparum; Mutation; Myanmar; Plasmodium falciparum; Quinolines | 2015 |
Artemisinin nanoformulation suitable for intravenous injection: Preparation, characterization and antimalarial activities.
Topics: Animals; Antimalarials; Artemisinins; Biological Availability; Drug Compounding; Injections, Intravenous; Malaria, Falciparum; Mice; Mice, Inbred NOD; Mice, SCID; Nanoparticles; Parasitemia; Particle Size; Plasmodium falciparum; Solubility | 2015 |
Induction of Multidrug Tolerance in Plasmodium falciparum by Extended Artemisinin Pressure.
Topics: Antimalarials; Artemisinins; Asia, Southeastern; Drug Tolerance; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum | 2015 |
Disagreement in genotyping results of drug resistance alleles of the Plasmodium falciparum dihydrofolate reductase (Pfdhfr) gene by allele-specific PCR (ASPCR) assays and Sanger sequencing.
Topics: Alleles; Antimalarials; Artemisinins; Codon; Dihydropteroate Synthase; DNA Primers; DNA, Protozoan; Drug Resistance; Drug Therapy, Combination; Genotyping Techniques; Humans; Malaria, Falciparum; Mutation; Plasmodium falciparum; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Pyrimethamine; Sensitivity and Specificity; Sequence Analysis, DNA; Sulfadoxine; Tetrahydrofolate Dehydrogenase | 2016 |
Artemisinin-resistant Plasmodium falciparum clinical isolates can infect diverse mosquito vectors of Southeast Asia and Africa.
Topics: Africa; Animals; Anopheles; Antimalarials; Artemisinins; Asia, Southeastern; Cambodia; Culicidae; Drug Resistance, Microbial; Humans; Insect Vectors; Malaria, Falciparum; Plasmodium falciparum; Protozoan Proteins; Sporozoites | 2015 |
Emergence of Mutations in the K13 Propeller Gene of Plasmodium falciparum Isolates from Dakar, Senegal, in 2013-2014.
Topics: Antimalarials; Artemisinins; Drug Resistance; Gene Expression; Humans; Malaria, Falciparum; Microfilament Proteins; Models, Molecular; Mutation; Plasmodium falciparum; Polymorphism, Genetic; Protein Structure, Secondary; Protein Structure, Tertiary; Protozoan Proteins; Senegal | 2016 |
[Assessment of Antimalarial Activity of Choline Derivatives against Plasmodium falciparum Growth in vitro by SYBR Green I Method].
Topics: Antimalarials; Artemisinins; Benzothiazoles; Choline; Diamines; Humans; Malaria, Falciparum; Organic Chemicals; Plasmodium falciparum; Quinolines | 2015 |
Optimum population-level use of artemisinin combination therapies: a modelling study.
Topics: Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Drug Administration Schedule; Drug Combinations; Drug Resistance; Ethanolamines; Fluorenes; Humans; Malaria, Falciparum; Models, Biological; Plasmodium falciparum; Quinolines; Treatment Failure | 2015 |
Natural selection of K13 mutants of Plasmodium falciparum in response to artemisinin combination therapies in Thailand.
Topics: Amino Acid Substitution; Antimalarials; Artemisinins; Codon; Drug Resistance; Drug Therapy, Combination; Genes, Protozoan; Humans; Malaria, Falciparum; Mutation; Plasmodium falciparum; Polymorphism, Genetic; Selection, Genetic; Sequence Analysis, DNA; Thailand | 2016 |
The Nobel Prize in Medicine 2015: Two drugs that changed global health.
Topics: Actinobacteria; Antimalarials; Antiparasitic Agents; Artemisia annua; Artemisinins; Drug Design; Global Health; History, 20th Century; History, 21st Century; Humans; Infectious Disease Medicine; Ivermectin; Malaria, Falciparum; Nobel Prize; Plasmodium falciparum | 2015 |
Polymorphisms of the artemisinin resistant marker (K13) in Plasmodium falciparum parasite populations of Grande Comore Island 10 years after artemisinin combination therapy.
Topics: Antimalarials; Artemisinins; Comoros; Drug Resistance; Gene Frequency; Genetic Markers; Haplotypes; Humans; Malaria, Falciparum; Plasmodium falciparum; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Sequence Analysis, DNA | 2015 |
Independent Emergence of the Plasmodium falciparum Kelch Propeller Domain Mutant Allele C580Y in Guyana.
Topics: Antimalarials; Artemisinins; DNA, Protozoan; Drug Resistance; Drug Therapy, Combination; Guyana; Humans; Malaria, Falciparum; Molecular Typing; Mutation; Plasmodium falciparum | 2016 |
Assessment of the Worldwide Antimalarial Resistance Network Standardized Procedure for In Vitro Malaria Drug Sensitivity Testing Using SYBR Green Assay for Field Samples with Various Initial Parasitemia Levels.
Topics: Antimalarials; Artemisinins; Atovaquone; Benzothiazoles; Biological Assay; Chloroquine; Diamines; DNA, Protozoan; Drug Resistance; Erythrocytes; Fluorescent Dyes; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Mefloquine; Organic Chemicals; Parasitemia; Plasmodium falciparum; Public Health Surveillance; Quinolines; Reproducibility of Results; Sensitivity and Specificity | 2016 |
Safety of artemisinins in first trimester of prospectively followed pregnancies: an observational study.
Topics: Abortion, Spontaneous; Adolescent; Adult; Antimalarials; Artemisinins; Female; Humans; Malaria, Falciparum; Malaria, Vivax; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Quinine; Thailand | 2016 |
Molecular surveillance of antimalarial drug resistance related genes in Plasmodium falciparum isolates from Eritrea.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Resistance; Eritrea; Female; Genes, Protozoan; Humans; Infant; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Polymorphism, Genetic; Prevalence; Young Adult | 2016 |
UK malaria treatment guidelines 2016.
Topics: Adult; Antimalarials; Artemisinins; Artesunate; Breast Feeding; Child; Child, Preschool; Female; Humans; Malaria; Malaria, Falciparum; Malaria, Vivax; Plasmodium falciparum; Plasmodium vivax; Pregnancy; Pregnancy Complications, Parasitic; Primaquine; Travel | 2016 |
K13 mutations and pfmdr1 copy number variation in Plasmodium falciparum malaria in Myanmar.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; DNA Copy Number Variations; DNA, Protozoan; Drug Combinations; Ethanolamines; Fluorenes; Humans; Malaria, Falciparum; Multidrug Resistance-Associated Proteins; Mutation; Myanmar; Plasmodium falciparum; Prospective Studies | 2016 |
Back on TRAC: New trial launched in bid to outpace multidrug-resistant malaria.
Topics: Antimalarials; Artemisinins; Asia, Southeastern; Drug Resistance, Multiple; Drug Therapy, Combination; Humans; India; Malaria; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Quinolines | 2016 |
Genomic epidemiology of artemisinin resistant malaria.
Topics: Africa; Antimalarials; Artemisinins; Asia, Southeastern; Drug Resistance; Malaria, Falciparum; Molecular Epidemiology; Plasmodium falciparum | 2016 |
SD Bioline malaria antigen Pf (HRP-2/pLHD) for assessing efficacy of artemisinin combination therapy against Plasmodium falciparum in pediatric patients in the Democratic Republic of the Congo.
Topics: Antigens, Protozoan; Antimalarials; Artemisinins; Child, Preschool; Democratic Republic of the Congo; Diagnostic Tests, Routine; Drug Resistance; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Infant; Malaria, Falciparum; Male; Plasmodium falciparum; Predictive Value of Tests; Sensitivity and Specificity; Time Factors | 2015 |
Primaquine plus artemisinin combination therapy for reduction of malaria transmission: promise and risk.
Topics: Adult; Antimalarials; Artemisinins; Child; Disease Transmission, Infectious; Drug Therapy, Combination; Humans; Malaria, Falciparum; Plasmodium falciparum; Primaquine; Risk Assessment | 2016 |
Plasmodium falciparum malaria: Convergent evolutionary trajectories towards delayed clearance following artemisinin treatment.
Topics: Animals; Antimalarials; Artemisinins; Asia, Southeastern; Biological Evolution; Drug Resistance; Erythrocytes; Evolution, Molecular; Genetic Fitness; Humans; Linkage Disequilibrium; Malaria, Falciparum; Models, Genetic; Mutation; Parasitemia; Plasmodium falciparum; Selection, Genetic | 2016 |
CRISPR-Cas9-modified pfmdr1 protects Plasmodium falciparum asexual blood stages and gametocytes against a class of piperazine-containing compounds but potentiates artemisinin-based combination therapy partner drugs.
Topics: Acrylamides; Antimalarials; Artemisinins; ATP-Binding Cassette Transporters; Clustered Regularly Interspaced Short Palindromic Repeats; DNA, Protozoan; Drug Resistance; Drug Synergism; Humans; Malaria, Falciparum; Multidrug Resistance-Associated Proteins; Piperazines; Plasmodium falciparum; Point Mutation; Polymorphism, Single Nucleotide | 2016 |
Examining Plasmodium falciparum and P. vivax clearance subsequent to antimalarial drug treatment in the Myanmar-China border area based on quantitative real-time polymerase chain reaction.
Topics: Antimalarials; Artemisinins; China; DNA, Protozoan; Drug Resistance; Genotype; Humans; Malaria, Falciparum; Malaria, Vivax; Microsatellite Repeats; Myanmar; Plasmodium falciparum; Plasmodium vivax; Protozoan Proteins; Real-Time Polymerase Chain Reaction | 2016 |
Evidence of a Mild Mutator Phenotype in Cambodian Plasmodium falciparum Malaria Parasites.
Topics: Alleles; Antimalarials; Artemisinins; Cambodia; Drug Resistance, Multiple; Gene Frequency; Humans; Indoles; Malaria, Falciparum; Mutation; MutL Protein Homolog 1; Phenotype; Plasmodium falciparum; Protozoan Proteins; Sodium-Potassium-Exchanging ATPase; Spiro Compounds | 2016 |
Malaria wars.
Topics: Antimalarials; Artemisinins; Cambodia; Chloroquine; Disease Eradication; Drug Resistance, Microbial; Humans; Malaria, Falciparum; Mekong Valley; Plasmodium falciparum | 2016 |
Skirmishing over the scope of the threat.
Topics: Animals; Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria, Falciparum; Mutation; Myanmar; Plasmodium falciparum | 2016 |
Limited Polymorphism of the Kelch Propeller Domain in Plasmodium malariae and P. ovale Isolates from Thailand.
Topics: Antimalarials; Artemisinins; Humans; Malaria, Falciparum; Mutation; Plasmodium malariae; Plasmodium ovale; Polymorphism, Genetic; Thailand | 2016 |
Evaluation of intensified behaviour change communication strategies in an artemisinin resistance setting.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Cambodia; Child; Cluster Analysis; Cross-Sectional Studies; Drug Resistance; Female; Humans; Information Dissemination; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Rural Health; Young Adult | 2016 |
A link between poor quality antimalarials and malaria drug resistance?
Topics: Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Malaria, Falciparum; Plasmodium falciparum; Pyrimethamine; Sulfadoxine | 2016 |
Village malaria worker performance key to the elimination of artemisinin-resistant malaria: a Western Cambodia health system assessment.
Topics: Adult; Antimalarials; Artemisinins; Cambodia; Community Health Workers; Cross-Sectional Studies; Disease Management; Drug Resistance; Female; Health Services Research; Humans; Malaria, Falciparum; Male; Middle Aged; Surveys and Questionnaires | 2016 |
Pyrrolidine-Acridine hybrid in Artemisinin-based combination: a pharmacodynamic study.
Topics: Acridines; Animals; Antimalarials; Artemether; Artemisinins; Drug Resistance, Multiple; Drug Therapy, Combination; Lethal Dose 50; Malaria, Falciparum; Mice; Parasitemia; Plasmodium falciparum; Pyrrolidines | 2016 |
Highly active ozonides selected against drug resistant malaria.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Disease Models, Animal; Female; Humans; Malaria, Falciparum; Mefloquine; Mice; Parasitemia; Plasmodium falciparum | 2016 |
How important is gametocyte clearance after malaria therapy?
Topics: Animals; Antimalarials; Artemisinins; Culicidae; Humans; Malaria, Falciparum; Plasmodium falciparum | 2016 |
Impact of using artemisinin-based combination therapy (ACT) in the treatment of uncomplicated malaria from Plasmodium falciparum in a non-endemic zone.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Drug Therapy, Combination; Female; Humans; Length of Stay; Malaria, Falciparum; Male; Middle Aged; Retrospective Studies; Treatment Outcome; Young Adult | 2016 |
Rosette-Disrupting Effect of an Anti-Plasmodial Compound for the Potential Treatment of Plasmodium falciparum Malaria Complications.
Topics: Animals; Antimalarials; Artemisinins; Drug Discovery; Drug Resistance; Erythrocytes; High-Throughput Screening Assays; Humans; Malaria, Cerebral; Malaria, Falciparum; Microcirculation; Microvessels; Parasite Load; Plasmodium falciparum; Pyridines | 2016 |
Lack of artemisinin resistance in Plasmodium falciparum in northwest Benin after 10 years of use of artemisinin-based combination therapy.
Topics: Anti-Infective Agents; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Benin; Child, Preschool; DNA, Protozoan; Drug Combinations; Drug Resistance; Ethanolamines; Fluorenes; Humans; Infant; Malaria, Falciparum; Plasmodium falciparum; Polymorphism, Genetic; Sequence Alignment | 2016 |
Ascorbic acid co-administration with artemisinin based combination therapies in falciparum malaria.
Topics: Artemisinins; Ascorbic Acid; Drug Combinations; Humans; Malaria, Falciparum | 2016 |
Prevalence of K13-propeller gene polymorphisms among Plasmodium falciparum parasites isolated from adult symptomatic patients in northern Uganda.
Topics: Adult; Animals; Antigens, Protozoan; Antimalarials; Artemisinins; Codon; DNA, Protozoan; Drug Resistance; Haplotypes; Humans; Malaria, Falciparum; Plasmodium falciparum; Polymorphism, Single Nucleotide; Prevalence; Sequence Analysis, DNA; Uganda; Young Adult | 2016 |
Artemisinin Resistance-Associated K13 Polymorphisms of Plasmodium falciparum in Southern Rwanda, 2010-2015.
Topics: Antimalarials; Artemisinins; Child; Child, Preschool; DNA, Protozoan; Drug Resistance; Female; Humans; Infant; Malaria, Falciparum; Male; Plasmodium falciparum; Polymorphism, Genetic; Rwanda; Sequence Analysis, DNA | 2016 |
Assessing the asymptomatic reservoir and dihydroartemisinin-piperaquine effectiveness in a low transmission setting threatened by artemisinin resistant Plasmodium falciparum.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Asymptomatic Diseases; Cambodia; Child; Child, Preschool; Cross-Sectional Studies; Drug Resistance; Female; Humans; Incidence; Infant; Infant, Newborn; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Prevalence; Quinolines; Real-Time Polymerase Chain Reaction; Treatment Outcome; Young Adult | 2016 |
Plasmodium falciparum infection in febrile Congolese children: prevalence of clinical malaria 10 years after introduction of artemisinin-combination therapies.
Topics: Antigens, Protozoan; Artemisinins; Child; Child, Preschool; Congo; Female; Fever; Hemoglobins; Hospitals; Humans; Infant; Malaria, Falciparum; Male; Pediatrics; Plasmodium falciparum; Polymerase Chain Reaction; Prevalence; Protozoan Proteins; Sickle Cell Trait | 2016 |
Compartmentalized Metabolic Engineering for Artemisinin Biosynthesis and Effective Malaria Treatment by Oral Delivery of Plant Cells.
Topics: Administration, Oral; Animals; Artemisinins; Chloroplasts; Malaria, Falciparum; Metabolic Engineering; Mice; Plant Cells; Plants, Genetically Modified | 2016 |
Optimal health and disease management using spatial uncertainty: a geographic characterization of emergent artemisinin-resistant Plasmodium falciparum distributions in Southeast Asia.
Topics: Anti-Infective Agents; Artemisinins; Asia, Southeastern; Communicable Diseases, Emerging; Disease Management; Drug Resistance; Geography; Health Status; Humans; Malaria, Falciparum; Plasmodium falciparum; Population Surveillance | 2016 |
Feasibility of Malaria Diagnosis and Management in Burkina Faso, Nigeria, and Uganda: A Community-Based Observational Study.
Topics: Administration, Oral; Antimalarials; Artemisinins; Artesunate; Burkina Faso; Child; Child, Preschool; Community Health Workers; Diagnostic Tests, Routine; Female; Humans; Infant; Malaria; Malaria, Falciparum; Male; Nigeria; Proteins; Referral and Consultation; Uganda | 2016 |
Polymorphisms in K13, pfcrt, pfmdr1, pfdhfr, and pfdhps in parasites isolated from symptomatic malaria patients in Burkina Faso.
Topics: Adolescent; Adult; Antigens, Bacterial; Antigens, Surface; Antimalarials; Artemisinins; Burkina Faso; Child; Child, Preschool; Drug Resistance; Drug Therapy, Combination; Humans; Infant; Malaria, Falciparum; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Young Adult | 2016 |
Population Parameters Underlying an Ongoing Soft Sweep in Southeast Asian Malaria Parasites.
Topics: Adaptation, Physiological; Animals; Antimalarials; Artemisinins; Drug Resistance; Gene Frequency; Genetics, Population; Humans; Malaria, Falciparum; Mutation; Mutation Rate; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Selection, Genetic; Sequence Analysis, DNA; Thailand | 2017 |
How to tackle antimalarial resistance?
Topics: Antimalarials; Artemisinins; Clinical Studies as Topic; Drug Resistance, Multiple; Humans; Malaria, Falciparum; Mutation; Plasmodium falciparum; Quinolines | 2017 |
Changing Antimalarial Drug Resistance Patterns Identified by Surveillance at Three Sites in Uganda.
Topics: Adolescent; Aminoquinolines; Antimalarials; Artemisinins; Cross-Sectional Studies; DNA, Protozoan; Drug Resistance; Ethanolamines; Female; Fluorenes; Folic Acid Antagonists; Genes, Protozoan; Humans; Lumefantrine; Malaria, Falciparum; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Mutation; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Sequence Analysis, DNA; Uganda | 2017 |
Molecular Epidemiology of Plasmodium falciparum kelch13 Mutations in Senegal Determined by Using Targeted Amplicon Deep Sequencing.
Topics: Amino Acid Sequence; Antimalarials; Artemisinins; DNA-Binding Proteins; Drug Resistance; Epidemiological Monitoring; Gene Expression; Genotype; Humans; Malaria, Falciparum; Molecular Epidemiology; Nuclear Proteins; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Senegal; Sequence Alignment; Sequence Analysis, DNA | 2017 |
Molecular surveillance of artemisinin resistance falciparum malaria among migrant goldmine workers in Myanmar.
Topics: Adult; Antimalarials; Artemisinins; Cross-Sectional Studies; Drug Resistance; Female; Genetic Markers; Gold; Humans; Malaria, Falciparum; Male; Miners; Mining; Myanmar; Plasmodium falciparum; Real-Time Polymerase Chain Reaction; Sequence Analysis, DNA; Transients and Migrants; Young Adult | 2017 |
Investigating antimalarial drug interactions of emetine dihydrochloride hydrate using CalcuSyn-based interactivity calculations.
Topics: Antimalarials; Artemisinins; Atovaquone; Chloroquine; Computational Biology; Drug Combinations; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Emetine; Humans; Malaria, Falciparum; Plasmodium falciparum; Proguanil | 2017 |
The Malaria TaqMan Array Card Includes 87 Assays for Plasmodium falciparum Drug Resistance, Identification of Species, and Genotyping in a Single Reaction.
Topics: Antimalarials; Artemisinins; Atovaquone; Chloroquine; Drug Resistance; Epidemiological Monitoring; Genotyping Techniques; Humans; Malaria, Falciparum; Plasmodium falciparum; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Pyrimethamine; Reagent Kits, Diagnostic; Sulfadoxine | 2017 |
Improving estimation of ACT treatment coverage in Africa.
Topics: Africa; Antimalarials; Artemisinins; Humans; Malaria, Falciparum | 2017 |
[Self-medication in the treatment of acute malaria: study based on users of private health drug stores in Ouagadougou, Burkina Faso].
Topics: Acute Disease; Adult; Antimalarials; Artemisinins; Burkina Faso; Child; Chloroquine; Cross-Sectional Studies; Drug Administration Schedule; Drug Combinations; Drug Resistance; Drug Utilization; Educational Status; Female; Health Knowledge, Attitudes, Practice; Humans; Malaria, Falciparum; Male; Middle Aged; Motivation; Pharmacies; Pyrimethamine; Self Medication; Sulfadoxine; Urban Population | 2008 |
No PfATPase6 S769N mutation found in Plasmodium falciparum isolates from China.
Topics: Animals; Antimalarials; Artemisinins; Calcium-Transporting ATPases; China; Codon; DNA, Protozoan; Drug Resistance; Humans; Malaria, Falciparum; Mutation; Plasmodium falciparum; Polymerase Chain Reaction; Sequence Analysis, DNA | 2008 |
Dynamic changes in white blood cell counts in uncomplicated Plasmodium falciparum and P. vivax malaria.
Topics: Acute Disease; Adolescent; Adult; Aged; Animals; Antimalarials; Artemisinins; Female; Humans; Leukocyte Count; Leukopenia; Malaria, Falciparum; Malaria, Vivax; Male; Middle Aged; Plasmodium falciparum; Plasmodium vivax; Young Adult | 2008 |
Different methodological approaches to the assessment of in vivo efficacy of three artemisinin-based combination antimalarial treatments for the treatment of uncomplicated falciparum malaria in African children.
Topics: Africa; Amodiaquine; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Child, Preschool; Databases as Topic; Drug Combinations; Ethanolamines; Fluorenes; Genotype; Humans; Infant; Lumefantrine; Malaria, Falciparum; Plasmodium falciparum; Polymerase Chain Reaction; Pyrimethamine; Sulfadoxine; Treatment Outcome | 2008 |
Should countries implementing an artemisinin-based combination malaria treatment policy also introduce rapid diagnostic tests?
Topics: Adolescent; Animals; Artemisinins; Child; Child, Preschool; Cost-Benefit Analysis; Diagnostic Tests, Routine; Ethanolamines; Fluorenes; Health Policy; Humans; Infant; Lumefantrine; Malaria, Falciparum; Mozambique; Parasitemia; Plasmodium falciparum; Pyrimethamine; Sulfadoxine | 2008 |
Plasmodium falciparum gametocyte dynamics in areas of different malaria endemicity.
Topics: Adolescent; Animals; Antimalarials; Artemisinins; Carrier State; Child; Child, Preschool; Drug Combinations; Endemic Diseases; Female; Gambia; Humans; Infant; Infant, Newborn; Kaplan-Meier Estimate; Malaria, Falciparum; Male; Multivariate Analysis; Parasitemia; Plasmodium falciparum; Proportional Hazards Models; Pyrimethamine; Retrospective Studies; Sulfadoxine; Tanzania; Thailand | 2008 |
Malariological baseline survey and in vitro antimalarial drug resistance in Gulu district, Northern Uganda.
Topics: Adolescent; Adult; Amodiaquine; Animals; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Cross-Sectional Studies; Developing Countries; Drug Resistance; Drug Therapy, Combination; Endemic Diseases; Ethanolamines; Evidence-Based Medicine; Female; Fluorenes; Health Surveys; Humans; Incidence; Infant; Lumefantrine; Malaria, Falciparum; Male; Parasitic Sensitivity Tests; Plasmodium falciparum; Refugees; Uganda; Young Adult | 2008 |
Pharmacodynamic interaction between monodesbutyl-benflumetol and artemisinin as well as proguanil in Plasmodium falciparum in vitro.
Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Dose-Response Relationship, Drug; Drug Synergism; Ethanolamines; Female; Fluorenes; Humans; Malaria, Falciparum; Male; Middle Aged; Parasitic Sensitivity Tests; Plasmodium falciparum; Proguanil; Thailand; Young Adult | 2008 |
Modelling the impact of artemisinin combination therapy and long-acting treatments on malaria transmission intensity.
Topics: Adolescent; Adult; Animals; Anti-Infective Agents; Artemisinins; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Infant, Newborn; Malaria, Falciparum; Male; Middle Aged; Models, Theoretical; Tanzania; Young Adult | 2008 |
High-level production of amorpha-4,11-diene, a precursor of the antimalarial agent artemisinin, in Escherichia coli.
Topics: Acetates; Ammonia; Anti-Infective Agents; Antimalarials; Artemisinins; Child, Preschool; Escherichia coli; Fermentation; Glucose; Humans; Malaria, Falciparum; Mevalonic Acid; Operon; Polycyclic Sesquiterpenes; Saccharomyces cerevisiae; Sesquiterpenes | 2009 |
The last man standing is the most resistant: eliminating artemisinin-resistant malaria in Cambodia.
Topics: Animals; Anti-Infective Agents; Antimalarials; Artemisinins; Cambodia; Drug Therapy, Combination; Humans; Malaria, Falciparum; Models, Theoretical; Plasmodium falciparum | 2009 |
Iodine-catalyzed one-pot synthesis and antimalarial activity evaluation of symmetrically and asymmetrically substituted 3,6-diphenyl[1,2,4,5]tetraoxanes.
Topics: Animals; Antimalarials; Artemisinins; Chemistry, Organic; Chemistry, Pharmaceutical; Chlorocebus aethiops; Drug Design; Inhibitory Concentration 50; Iodine; Malaria, Falciparum; Models, Chemical; Molecular Structure; Plasmodium falciparum; Tetraoxanes; Vero Cells | 2009 |
Influence of rapid malaria diagnostic tests on treatment and health outcome in fever patients, Zanzibar: a crossover validation study.
Topics: Adult; Antimalarials; Artemisinins; Child; Child, Preschool; Cross-Over Studies; Diagnostic Tests, Routine; Drug Therapy, Combination; Fever; Humans; Malaria, Falciparum; Odds Ratio; Prescriptions; Tanzania; Treatment Outcome | 2009 |
In vitro erythrocytic uptake studies of artemisinin and selected derivatives using LC-MS and 2D-QSAR analysis of uptake in parasitized erythrocytes.
Topics: Animals; Anti-Infective Agents; Artemisinins; Chromatography, Liquid; Erythrocytes; Humans; Linear Models; Malaria, Falciparum; Mass Spectrometry; Plasmodium falciparum; Quantitative Structure-Activity Relationship | 2009 |
Focusing on quality patient care in the new global subsidy for malaria medicines.
Topics: Antimalarials; Artemisinins; Delivery of Health Care; Drug Therapy, Combination; Financing, Organized; Global Health; Health Services Accessibility; Humans; International Cooperation; Malaria, Falciparum; Quality of Health Care | 2009 |
Artemisinin-resistant malaria in Asia.
Topics: Adult; Animals; Antimalarials; Artemisinins; Asia, Southeastern; Bangladesh; Communicable Disease Control; Drug Resistance; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Middle Aged; Plasmodium falciparum; Treatment Failure; Young Adult | 2009 |
PfHRP2 and PfLDH antigen detection for monitoring the efficacy of artemisinin-based combination therapy (ACT) in the treatment of uncomplicated falciparum malaria.
Topics: Amodiaquine; Antigens, Protozoan; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Benin; Blood; Child, Preschool; Drug Combinations; Drug Monitoring; Drug Therapy, Combination; Ethanolamines; Fluorenes; Follow-Up Studies; Humans; Infant; L-Lactate Dehydrogenase; Malaria, Falciparum; Microscopy; Molecular Diagnostic Techniques; Protozoan Proteins; Pyrimethamine; Sensitivity and Specificity; Sulfadoxine; Treatment Outcome | 2009 |
Artemisinin resistance on the Thai-Cambodian border.
Topics: Amodiaquine; Antimalarials; Artemisinins; Burkina Faso; Cambodia; Drug Combinations; Drug Resistance; Humans; Malaria, Falciparum; Thailand | 2009 |
In vivo parasitological measures of artemisinin susceptibility.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Resistance; Endemic Diseases; Humans; Infant; Kaplan-Meier Estimate; Malaria, Falciparum; Middle Aged; Parasitemia; Plasmodium falciparum; Recurrence | 2010 |
A non-radioactive DAPI-based high-throughput in vitro assay to assess Plasmodium falciparum responsiveness to antimalarials--increased sensitivity of P. falciparum to chloroquine in Senegal.
Topics: Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Fluorescent Dyes; Genotype; Humans; Indoles; Malaria, Falciparum; Plasmodium falciparum; Senegal; Staining and Labeling | 2010 |
Flow cytometry for the evaluation of anti-plasmodial activity of drugs on Plasmodium falciparum gametocytes.
Topics: Anti-Infective Agents; Antimalarials; Artemisinins; Chloroquine; Drug Evaluation, Preclinical; Flow Cytometry; Inhibitory Concentration 50; Malaria, Falciparum; Microscopy; Parasitemia; Parasitic Sensitivity Tests; Plasmodium falciparum; Primaquine; Xanthurenates | 2010 |
Rapid and effective malaria control in Cambodia through mass administration of artemisinin-piperaquine.
Topics: Administration, Oral; Adolescent; Adult; Anti-Infective Agents; Antimalarials; Artemisinins; Cambodia; Child; Drug Administration Schedule; Drug Therapy, Combination; Endemic Diseases; Female; Humans; Malaria, Falciparum; Male; Parasitemia; Pilot Projects; Plasmodium falciparum; Population Surveillance; Primaquine; Quinolines; Treatment Outcome | 2010 |
Another step towards preventing artemisinin resistance.
Topics: Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria, Falciparum; Practice Guidelines as Topic; World Health Organization | 2010 |
High heritability of malaria parasite clearance rate indicates a genetic basis for artemisinin resistance in western Cambodia.
Topics: Antimalarials; Artemisinins; Cambodia; Drug Resistance; Genetic Variation; Genotype; Humans; Malaria, Falciparum; Microsatellite Repeats; Plasmodium falciparum; Quantitative Trait, Heritable | 2010 |
Role of pfmdr1 amplification and expression in induction of resistance to artemisinin derivatives in Plasmodium falciparum.
Topics: Alleles; Animals; Antimalarials; Artemisinins; Drug Resistance; Gene Amplification; Gene Dosage; Gene Expression; Genes, Protozoan; Humans; In Vitro Techniques; Malaria, Falciparum; Mefloquine; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; RNA, Messenger; RNA, Protozoan | 2010 |
A call to action: addressing the challenge of artemisinin-resistant malaria.
Topics: Animals; Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria, Falciparum; Plasmodium falciparum | 2010 |
Inferred relatedness and heritability in malaria parasites.
Topics: Antimalarials; Artemisinins; Drug Resistance; Genetic Variation; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Phenotype; Phylogeny; Plasmodium falciparum | 2010 |
Plasmodium falciparum ATP6 not under selection during introduction of artemisinin combination therapy in Peru.
Topics: Antimalarials; Artemisinins; Drug Therapy, Combination; Genotype; Humans; Malaria, Falciparum; Peru; Plasmodium falciparum | 2010 |
Use of HRP-2-based rapid diagnostic test for Plasmodium falciparum malaria: assessing accuracy and cost-effectiveness in the villages of Dielmo and Ndiop, Senegal.
Topics: Adolescent; Antigens, Protozoan; Antimalarials; Artemisinins; Child; Child, Preschool; Cost-Benefit Analysis; Cross-Sectional Studies; Diagnostic Tests, Routine; Drug Therapy, Combination; Female; Follow-Up Studies; Health Care Costs; Humans; Infant; Malaria, Falciparum; Male; Microscopy; Parasitemia; Plasmodium falciparum; Predictive Value of Tests; Protozoan Proteins; Reagent Kits, Diagnostic; Senegal | 2010 |
Monitoring for Plasmodium falciparum drug resistance to artemisinin and artesunate in Binh Phuoc Province, Vietnam: 1998-2009.
Topics: Adolescent; Adult; Anti-Infective Agents; Antimalarials; Artemisinins; Artesunate; Child; Drug Resistance; Female; Follow-Up Studies; Genotype; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Male; Parasitemia; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymerase Chain Reaction; Recurrence; Sensitivity and Specificity; Time Factors; Vietnam; Young Adult | 2010 |
The development of artemisinin resistance in malaria: reasons and solutions.
Topics: Antimalarials; Artemisinins; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Plasmodium falciparum | 2010 |
Dynamics of Plasmodium falciparum parasitemia regarding combined treatment regimens for acute uncomplicated malaria, Antioquia, Colombia.
Topics: Administration, Oral; Animals; Antimalarials; Artemisinins; Artesunate; Clinical Protocols; Colombia; Drug Therapy, Combination; Female; Humans; Malaria; Malaria, Falciparum; Male; Mefloquine; Parasitemia; Patient Compliance; Plasmodium falciparum; Primaquine; Treatment Outcome | 2010 |
Availability of essential health services in post-conflict Liberia.
Topics: Adult; Anti-Infective Agents; Artemisinins; Child; Child Health Services; Community Health Services; Delivery, Obstetric; Emergency Medical Services; Female; Health Care Surveys; Health Services Accessibility; HIV Infections; Humans; Liberia; Malaria, Falciparum; Male; Maternal Health Services; Mental Health Services; Middle Aged; Rural Health Services; Time Factors | 2010 |
pfmdr1 amplification associated with clinical resistance to mefloquine in West Africa: implications for efficacy of artemisinin combination therapies.
Topics: Adult; Africa, Western; Artemisinins; Drug Resistance; Drug Therapy, Combination; Gene Dosage; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Male; Mefloquine; Multidrug Resistance-Associated Proteins; Treatment Failure | 2010 |
Reducing Plasmodium falciparum malaria transmission in Africa: a model-based evaluation of intervention strategies.
Topics: Africa; Animals; Anopheles; Artemisinins; Humans; Insect Vectors; Malaria, Falciparum; Models, Theoretical; Mosquito Control; Plasmodium falciparum | 2010 |
Universal access to malaria medicines: innovation in financing and delivery.
Topics: Antimalarials; Artemisinins; Drug Costs; Drug Industry; Drug Resistance; Drug Therapy, Combination; Health Services Accessibility; Humans; Malaria, Falciparum; Private Sector; Public Sector | 2010 |
UK treatment of malaria.
Topics: Anti-Infective Agents; Antimalarials; Artemisinins; Child; Humans; Malaria; Malaria, Falciparum; Treatment Outcome; United Kingdom | 2011 |
Current malaria management: guideline 2009.
Topics: Anti-Infective Agents; Antimalarials; Artemisinins; Humans; Indonesia; Malaria, Falciparum; Malaria, Vivax; Risk Factors | 2010 |
Better surveillance is needed to halt spread of artemisinin resistant malaria.
Topics: Antimalarials; Artemisinins; Drug Resistance, Multiple; Humans; Malaria, Falciparum | 2010 |
In areas of low transmission, is the presumptive treatment of febrile but bloodsmear-negative patients for malaria validated by the results of PCR-based testing?
Topics: Antigens, Protozoan; Antimalarials; Artemisinins; Female; Fever; Humans; Malaria; Malaria, Falciparum; Male; Plasmodium falciparum; Polymerase Chain Reaction; Sudan | 2010 |
Brazilian Plasmodium falciparum isolates: investigation of candidate polymorphisms for artemisinin resistance before introduction of artemisinin-based combination therapy.
Topics: Adenosine Triphosphatases; Adult; Antimalarials; Artemisinins; Brazil; DNA, Protozoan; Drug Resistance; Genetic Variation; Genotype; Humans; Malaria, Falciparum; Male; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Polymerase Chain Reaction; Sequence Analysis, DNA | 2010 |
Artemisinin resistance--the clock is ticking.
Topics: Africa; Anti-Infective Agents; Artemisinins; Asia, Southeastern; Cambodia; Drug Resistance; Global Health; Humans; India; Malaria, Falciparum; Plasmodium falciparum; Travel | 2010 |
WHO unveils plan to stop artemisinin resistance "dead in its tracks".
Topics: Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria, Falciparum | 2011 |
Has artemisinin resistance spread already?
Topics: Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria, Falciparum; World Health Organization | 2011 |
Epidemic of Plasmodium falciparum malaria in Central India, an area where chloroquine has been replaced by artemisinin-based combination therapy.
Topics: Adolescent; Age Distribution; Antimalarials; Artemisinins; Child; Chloroquine; Drug Therapy, Combination; Epidemics; Female; Humans; India; Infant; Infant, Newborn; Insecticide Resistance; Insecticides; Malaria, Falciparum; Male; Prevalence; Rural Health; Treatment Outcome | 2011 |
Measuring the AMFm.
Topics: Antimalarials; Artemisinins; Developing Countries; Drug Costs; Humans; Malaria, Falciparum | 2011 |
Artemisinin-induced parasite dormancy: a plausible mechanism for treatment failure.
Topics: Animals; Antimalarials; Artemisinins; Malaria, Falciparum; Models, Statistical; Plasmodium falciparum; Treatment Failure | 2011 |
In vitro activity of new artemisinin derivatives against Plasmodium falciparum clinical isolates from Gabon.
Topics: Adolescent; Antimalarials; Artemisinins; Child; Child, Preschool; Gabon; Humans; Infant; Inhibitory Concentration 50; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum | 2011 |
Prevalence of molecular markers of anti-malarial drug resistance in Plasmodium vivax and Plasmodium falciparum in two districts of Nepal.
Topics: Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Drug Resistance; Humans; Malaria, Falciparum; Malaria, Vivax; Nepal; Plasmodium falciparum; Plasmodium vivax; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Protozoan Proteins; Pyrimethamine; Sulfadoxine | 2011 |
Antimalarial activity of endoperoxide compound 6-(1,2,6,7-tetraoxaspiro[7.11]nonadec-4-yl)hexan-1-ol.
Topics: Administration, Oral; Animals; Antimalarials; Artemisinins; Cell Line, Tumor; Drug Therapy, Combination; Erythrocytes; Heterocyclic Compounds, 2-Ring; Hexanols; Humans; Malaria; Malaria, Falciparum; Mice; Mice, Inbred ICR; Molecular Structure; Parasitemia; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Rats; Spiro Compounds; Survival Analysis; Tetraoxanes | 2011 |
Novel polymorphisms in Plasmodium falciparum ABC transporter genes are associated with major ACT antimalarial drug resistance.
Topics: Animals; Antimalarials; Artemisinins; ATP-Binding Cassette Transporters; Base Sequence; Drug Resistance; Ethanolamines; Fluorenes; Gene Frequency; Genotype; Haplotypes; Humans; Inhibitory Concentration 50; Lumefantrine; Malaria, Falciparum; Mefloquine; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins | 2011 |
The transit phase of migration: circulation of malaria and its multidrug-resistant forms in Africa.
Topics: Africa; Antimalarials; Artemisinins; Drug Resistance, Multiple; Emigration and Immigration; Health Policy; Health Services; Humans; Malaria, Falciparum; Plasmodium falciparum; Uganda | 2011 |
Artemisinin activity against Plasmodium falciparum requires hemoglobin uptake and digestion.
Topics: Animals; Antimalarials; Artemisinins; Biological Transport, Active; Cysteine Endopeptidases; Endocytosis; Erythrocytes; Gene Deletion; Genes, Protozoan; Hemoglobins; Host-Parasite Interactions; Humans; Malaria, Falciparum; Parasitemia; Plasmodium falciparum | 2011 |
Reduced in vitro susceptibility to artemisinin derivatives associated with multi-resistance in a traveller returning from South-East Asia.
Topics: Antimalarials; Artemisinins; Asia, Southeastern; Doxycycline; Drug Resistance; Female; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Middle Aged; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Quinine; Travel; Treatment Outcome | 2011 |
Phenotypic changes in artemisinin-resistant Plasmodium falciparum lines in vitro: evidence for decreased sensitivity to dormancy and growth inhibition.
Topics: Animals; Antimalarials; Artemisinins; Cell Culture Techniques; Drug Resistance; Erythrocytes; Genotype; Humans; Inhibitory Concentration 50; Life Cycle Stages; Malaria, Falciparum; Microscopy; Parasitic Sensitivity Tests; Phenotype; Plasmodium falciparum; Recurrence | 2012 |
Phenotypic and genotypic analysis of in vitro-selected artemisinin-resistant progeny of Plasmodium falciparum.
Topics: Antimalarials; Artemisinins; Benzothiazoles; Cell Culture Techniques; Diamines; Dose-Response Relationship, Drug; Drug Resistance; Erythrocytes; Gene Dosage; Genotype; Humans; Hypoxanthine; Inhibitory Concentration 50; Malaria, Falciparum; Merozoites; Microscopy; Multidrug Resistance-Associated Proteins; Organic Chemicals; Parasitic Sensitivity Tests; Phenotype; Plasmodium falciparum; Quinolines; Recurrence | 2012 |
Prevalence of single nucleotide polymorphisms in the Plasmodium falciparum multidrug resistance gene (Pfmdr-1) in Korogwe District in Tanzania before and after introduction of artemisinin-based combination therapy.
Topics: Antimalarials; Artemisinins; ATP-Binding Cassette Transporters; Codon; Cross-Sectional Studies; Drug Resistance, Multiple; Drug Therapy, Combination; Ethanolamines; Fluorenes; Haplotypes; Humans; Lumefantrine; Malaria, Falciparum; Plasmodium falciparum; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Prevalence; Protozoan Proteins; Tanzania | 2011 |
The use of paediatric artemisinin combinations in sub-Saharan Africa: a snapshot questionnaire survey of health care personnel.
Topics: Africa South of the Sahara; Antimalarials; Artemisinins; Child; Dosage Forms; Drug Combinations; Drug Industry; Drug Utilization; Health Personnel; Health Policy; Humans; Malaria, Falciparum; Marketing of Health Services; Patient Safety; Practice Patterns, Physicians'; Quality of Health Care; Surveys and Questionnaires | 2011 |
Risk factors for gametocyte carriage in uncomplicated falciparum malaria in children before and after artemisinin-based combination treatments.
Topics: Adolescent; Aminoquinolines; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Infant; Malaria, Falciparum; Male; Risk Factors | 2011 |
Priority setting for the implementation of artemisinin-based combination therapy policy in Tanzania: evaluation against the accountability for reasonableness framework.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Cost-Benefit Analysis; Data Collection; Drug Combinations; Drug Industry; Drug Resistance, Multiple; Ethanolamines; Fluorenes; Health Priorities; Humans; Malaria, Falciparum; Sample Size; Social Responsibility; Tanzania; Treatment Outcome | 2012 |
Molecular markers in plasmodium falciparum linked to resistance to anti-malarial drugs in samples imported from Africa over an eight-year period (2002-2010): impact of the introduction of artemisinin combination therapy.
Topics: Africa; Alleles; Animals; Antimalarials; Artemisinins; DNA, Protozoan; Drug Combinations; Drug Resistance; Gene Frequency; Genotype; Humans; Malaria, Falciparum; Multidrug Resistance-Associated Proteins; Mutant Proteins; Mutation, Missense; Peptide Synthases; Plasmodium falciparum; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Pyrimethamine; Sulfadoxine; Tetrahydrofolate Dehydrogenase; Travel | 2012 |
Antigen persistence of rapid diagnostic tests in pregnant women in Nanoro, Burkina Faso, and the implications for the diagnosis of malaria in pregnancy.
Topics: Adult; Analysis of Variance; Anti-Infective Agents; Antigens, Protozoan; Artemisinins; Biomarkers; Burkina Faso; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Humans; L-Lactate Dehydrogenase; Malaria, Falciparum; Multienzyme Complexes; Plasmodium falciparum; Pregnancy; Pregnancy Complications, Parasitic; Protozoan Proteins; Real-Time Polymerase Chain Reaction; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase; Treatment Outcome | 2012 |
Relationship between treatment-seeking behaviour and artemisinin drug quality in Ghana.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Caregivers; Child, Preschool; Commerce; Counterfeit Drugs; Drug Therapy, Combination; Educational Status; Ghana; Humans; Magnetic Resonance Spectroscopy; Malaria, Falciparum; Patient Acceptance of Health Care; Plasmodium falciparum; Quality Control | 2012 |
A major genome region underlying artemisinin resistance in malaria.
Topics: Antimalarials; Artemisinins; Cambodia; DNA Copy Number Variations; Drug Resistance; Gene Frequency; Genetic Association Studies; Genome, Protozoan; Haplotypes; Humans; Laos; Malaria, Falciparum; Microsatellite Repeats; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Selection, Genetic; Thailand | 2012 |
Molecular monitoring of Plasmodium falciparum drug susceptibility at the time of the introduction of artemisinin-based combination therapy in Yaoundé, Cameroon: implications for the future.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Cameroon; Child; Child, Preschool; DNA, Protozoan; Drug Resistance; Drug Therapy, Combination; Female; Genotype; Humans; Infant; Infant, Newborn; Malaria, Falciparum; Male; Membrane Transport Proteins; Middle Aged; Multidrug Resistance-Associated Proteins; Mutation, Missense; Plasmodium falciparum; Prevalence; Protozoan Proteins; Real-Time Polymerase Chain Reaction; Sentinel Surveillance; Young Adult | 2012 |
Routine delivery of artemisinin-based combination treatment at fixed health facilities reduces malaria prevalence in Tanzania: an observational study.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Child, Preschool; Cross-Sectional Studies; Drug Combinations; Drug Therapy, Combination; Health Facilities; Health Services Research; Humans; Infant; Malaria, Falciparum; Parasitemia; Prevalence; Pyrimethamine; Sulfadoxine; Tanzania; Treatment Outcome; Young Adult | 2012 |
Optimal designs for population pharmacokinetic studies of the partner drugs co-administered with artemisinin derivatives in patients with uncomplicated falciparum malaria.
Topics: Adult; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Models, Statistical; Pharmaceutical Preparations; Pregnancy; Research Design; Time Factors | 2012 |
Optimising strategies for Plasmodium falciparum malaria elimination in Cambodia: primaquine, mass drug administration and artemisinin resistance.
Topics: Antimalarials; Artemisinins; Cambodia; Drug Resistance; Humans; Malaria, Falciparum; Models, Theoretical; Population Surveillance; Prevalence; Primaquine | 2012 |
Artemisinin resistance containment project in Thailand. (I): Implementation of electronic-based malaria information system for early case detection and individual case management in provinces along the Thai-Cambodian border.
Topics: Animals; Antimalarials; Artemisinins; Communicable Disease Control; Drug Resistance; Electronic Data Processing; Humans; Information Systems; Malaria, Falciparum; Plasmodium falciparum; Thailand | 2012 |
Reductions in artemisinin-based combination therapy consumption after the nationwide scale up of routine malaria rapid diagnostic testing in Zambia.
Topics: Antimalarials; Artemisinins; Child, Preschool; Databases, Factual; Diagnostic Tests, Routine; Drug Prescriptions; Humans; Malaria, Falciparum; Pilot Projects; Plasmodium falciparum; Retrospective Studies; Zambia | 2012 |
[More artemisinin-resistant malaria in Thailand].
Topics: Antimalarials; Artemisinins; Drug Resistance; Global Health; Humans; Malaria, Falciparum; Plasmodium falciparum; Thailand | 2012 |
Combined receptor-based and ligand-based approach to delineate the mode of binding of guaianolide-endoperoxides to PfATP6.
Topics: Antimalarials; Artemisinins; Calcium-Transporting ATPases; Drug Design; Humans; Malaria, Falciparum; Molecular Docking Simulation; Peroxides; Plasmodium falciparum; Sesquiterpenes, Guaiane; Structural Homology, Protein | 2012 |
Artemisinin resistance containment project in Thailand. II: Responses to mefloquine-artesunate combination therapy among falciparum malaria patients in provinces bordering Cambodia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Artesunate; Cambodia; Child; Child, Preschool; Drug Resistance; Drug Therapy, Combination; Epidemiological Monitoring; Female; Humans; Infant; Infant, Newborn; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Thailand; Treatment Outcome; Young Adult | 2012 |
Resistance to artemisinin-based combination therapy.
Topics: Animals; Antimalarials; Artemisinins; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Plasmodium falciparum | 2012 |
An image-based drug susceptibility assay targeting the placental sequestration of Plasmodium falciparum-infected erythrocytes.
Topics: Algorithms; Animals; Antimalarials; Artemisinins; Automation; Brefeldin A; CD36 Antigens; Cell Adhesion; Cell Line; Cell Survival; Chondroitin Sulfates; Drug Evaluation, Preclinical; Erythrocytes; Female; Humans; Image Processing, Computer-Assisted; Malaria, Falciparum; Placenta; Plasmodium falciparum; Pregnancy | 2012 |
Status of potential PfATP6 molecular markers for artemisinin resistance in Suriname.
Topics: Artemisinins; Calcium-Transporting ATPases; DNA, Protozoan; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Mutation, Missense; Plasmodium falciparum; Point Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Suriname | 2012 |
New treatment policy of malaria as a part of malaria control program in Indonesia.
Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Disease Eradication; Drug Resistance; Drug Therapy, Combination; Health Policy; Humans; Indonesia; Malaria, Falciparum; Malaria, Vivax; Practice Guidelines as Topic; Primaquine | 2012 |
Combining individual patient data and aggregate data in mixed treatment comparison meta-analysis: Individual patient data may be beneficial if only for a subset of trials.
Topics: Artemisinins; Data Interpretation, Statistical; Drug Therapy, Combination; Humans; Malaria, Falciparum; Meta-Analysis as Topic; Models, Statistical; Plasmodium falciparum; Randomized Controlled Trials as Topic; Treatment Outcome | 2013 |
Focused Screening and Treatment (FSAT): a PCR-based strategy to detect malaria parasite carriers and contain drug resistant P. falciparum, Pailin, Cambodia.
Topics: Artemisinins; Atovaquone; Base Sequence; Cambodia; Carrier State; Cross-Sectional Studies; Demography; Drug Combinations; Drug Resistance; Humans; Interviews as Topic; Malaria, Falciparum; Mass Screening; Molecular Sequence Data; Plasmodium falciparum; Polymerase Chain Reaction; Prevalence; Primaquine; Proguanil; Sequence Analysis, DNA; Statistics, Nonparametric | 2012 |
Artemisinin-resistant malaria in the Asia-Pacific region.
Topics: Antimalarials; Artemisinins; Asia; Australia; Drug Resistance; Humans; Malaria, Falciparum | 2013 |
Molecular assessment of atpase6 mutations associated with artemisinin resistance among unexposed and exposed Plasmodium falciparum clinical isolates to artemisinin-based combination therapy.
Topics: Adenosine Triphosphatases; Animals; Antimalarials; Artemisinins; Base Sequence; DNA, Protozoan; Drug Resistance; Drug Therapy, Combination; Gene Dosage; Genes, Protozoan; Haplotypes; Humans; Iran; Malaria, Falciparum; Mutation; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins | 2012 |
Editorial commentary: single-dose primaquine as gametocytocidal treatment in patients with uncomplicated falciparum malaria.
Topics: Antimalarials; Artemisinins; Artesunate; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Parasitemia; Plasmodium falciparum | 2013 |
Primaquine to prevent transmission of falciparum malaria.
Topics: Antimalarials; Artemisinins; Drug Resistance; Drug Therapy, Combination; Hemolysis; Humans; Malaria, Falciparum; Plasmodium falciparum; Primaquine | 2013 |
Characterization of the Plasmodium falciparum sarcoplasmic/endoplasmic reticulum Ca2+-ATPase gene in samples from Equatorial Guinea before implementation of artemisinin-based combination therapy.
Topics: Animals; Antimalarials; Artemisinins; DNA, Protozoan; Equatorial Guinea; Humans; Malaria, Falciparum; Plasmodium falciparum; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Sarcoplasmic Reticulum Calcium-Transporting ATPases | 2013 |
Reduction of multiplicity of infections but no change in msp2 genetic diversity in Plasmodium falciparum isolates from Congolese children after introduction of artemisinin-combination therapy.
Topics: Antigens, Protozoan; Antimalarials; Artemisinins; Child; Child, Preschool; Congo; Drug Therapy, Combination; Gene Frequency; Genes, Protozoan; Genetic Variation; Humans; Infant; Malaria, Falciparum; Molecular Epidemiology; Plasmodium falciparum; Protozoan Proteins; Recurrence | 2012 |
Mutation analysis in pfmdr1 and pfmrp1 as potential candidate genes for artemisinin resistance in Plasmodium falciparum clinical isolates 4years after implementation of artemisinin combination therapy in Iran.
Topics: Artemisinins; Drug Resistance; Gene Dosage; Haplotypes; Humans; Iran; Malaria, Falciparum; Molecular Typing; Multidrug Resistance-Associated Proteins; Mutation; Mutation Rate; Plasmodium falciparum; Real-Time Polymerase Chain Reaction | 2013 |
Are artemisinin-based combination therapies effective against Plasmodium malariae?
Topics: Adult; Antimalarials; Artemether; Artemisinins; Drug Combinations; Ethanolamines; Fluorenes; HIV Infections; Humans; Lumefantrine; Malaria, Falciparum; Male; Plasmodium malariae; Treatment Failure | 2013 |
Molecular monitoring of antimalarial drug resistance among Plasmodium falciparum field isolates from Odisha, India.
Topics: Antimalarials; Artemisinins; Chloroquine; Cross-Sectional Studies; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; India; Malaria, Falciparum; Mutation, Missense; Plasmodium falciparum; Prevalence; Protozoan Proteins; Pyrimethamine; Sulfadoxine | 2013 |
[Artemisinine and artesunate in the treatment of malaria in Vietnam (1984-1999)].
Topics: Adult; Anti-Bacterial Agents; Antimalarials; Artemisinins; Artesunate; Child; Doxycycline; Drug Combinations; Drug Resistance; Drugs, Chinese Herbal; Humans; Malaria, Falciparum; Malaria, Vivax; Sesquiterpenes; Tetracycline; Vietnam | 2002 |
Parasitology. A requiem for chloroquine.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Drug Therapy, Combination; Drug Tolerance; Evolution, Molecular; Genes, Protozoan; Humans; Malaria, Falciparum; Membrane Proteins; Membrane Transport Proteins; Mutation; Plasmodium falciparum; Protozoan Proteins; Sesquiterpenes; Tetrahydrofolate Dehydrogenase | 2002 |
Analysis of pfcrt, pfmdr1, dhfr, and dhps mutations and drug sensitivities in Plasmodium falciparum isolates from patients in Vietnam before and after treatment with artemisinin.
Topics: Animals; Antimalarials; Artemisinins; ATP-Binding Cassette Transporters; Dihydropteroate Synthase; Drug Resistance; Genotype; Malaria, Falciparum; Membrane Proteins; Membrane Transport Proteins; Mutation; Plasmodium falciparum; Protozoan Proteins; Sesquiterpenes; Tetrahydrofolate Dehydrogenase; Vietnam | 2003 |
Ceramide mediates growth inhibition of the Plasmodium falciparum parasite.
Topics: Animals; Antiprotozoal Agents; Apoptosis; Artemisinins; Ceramides; Glutathione; Growth Inhibitors; Lysophospholipids; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Sesquiterpenes; Sphingomyelin Phosphodiesterase; Sphingosine | 2003 |
Safety evaluations of drugs containing artemisinin derivatives for the treatment of malaria.
Topics: Animals; Antimalarials; Artemisinins; Drug Therapy, Combination; Evaluation Studies as Topic; Malaria, Falciparum; Sesquiterpenes; Treatment Outcome; United States; United States Food and Drug Administration; World Health Organization | 2003 |
Delayed clearance of Plasmodium falciparum in patients with human immunodeficiency virus co-infection treated with artemisinin.
Topics: Adolescent; Adult; Anti-Infective Agents; Artemisinins; Comorbidity; Enzyme-Linked Immunosorbent Assay; Female; Hemoglobins; HIV Infections; HIV Seronegativity; Humans; Immunocompromised Host; Leukocyte Count; Malaria, Falciparum; Male; Middle Aged; Sesquiterpenes; Time Factors; Treatment Outcome | 2002 |
Structure-activity relationships of the antimalarial agent artemisinin. 8. design, synthesis, and CoMFA studies toward the development of artemisinin-based drugs against leishmaniasis and malaria.
Topics: Animals; Antimalarials; Antiprotozoal Agents; Artemisinins; Clone Cells; Drug Design; Inhibitory Concentration 50; L-Lactate Dehydrogenase; Leishmania donovani; Malaria, Falciparum; Models, Molecular; Molecular Conformation; Plasmodium falciparum; Sesquiterpenes; Static Electricity; Stereoisomerism; Structure-Activity Relationship | 2003 |
Drug combinations for malaria: time to ACT?
Topics: Africa; Antimalarials; Artemisinins; Asia, Southeastern; Communicable Diseases, Emerging; Drug Resistance; Drug Therapy, Combination; Humans; Incidence; Malaria; Malaria, Falciparum; Parasitemia; Sesquiterpenes | 2004 |
Naphthoquine phosphate and its combination with artemisinine.
Topics: Animals; Antimalarials; Artemisinins; Clinical Trials as Topic; Drug Combinations; Drug Synergism; Half-Life; Humans; Malaria, Falciparum; Mice; Plasmodium berghei; Plasmodium falciparum; Sesquiterpenes | 2004 |
Therapeutic efficacies of antimalarial drugs in the treatment of uncomplicated, Plasmodium falciparum malaria in Assam, north-eastern India.
Topics: Adolescent; Adult; Aged; Animals; Anti-Infective Agents; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Combinations; Female; Humans; India; Infant; Malaria, Falciparum; Male; Middle Aged; Parasitemia; Pyrimethamine; Quinine; Sesquiterpenes; Sulfadoxine | 2003 |
Plasmodium falciparum-based bioassay for measurement of artemisinin derivatives in plasma or serum.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Biological Assay; Biotransformation; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Electrochemistry; Hot Temperature; Humans; In Vitro Techniques; Macaca mulatta; Malaria, Falciparum; Plasmodium falciparum; Reproducibility of Results; Sesquiterpenes | 2004 |
Defective DNA repair as a potential mechanism for the rapid development of drug resistance in Plasmodium falciparum.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; DNA Damage; DNA Repair; Drug Resistance; Drug Resistance, Multiple; Humans; Malaria, Falciparum; Mefloquine; Parasitic Sensitivity Tests; Phenanthrenes; Plasmodium falciparum; Pyrimethamine; Quinine; Sesquiterpenes; Sulfanilamide; Sulfanilamides; Ultraviolet Rays | 2004 |
Is combination therapy for malaria based on user-fees worthwhile and equitable to consumers? Assessment of costs and willingness to pay in Southeast Nigeria.
Topics: Antimalarials; Artemisinins; Cost-Benefit Analysis; Cross-Sectional Studies; Drug Therapy, Combination; Female; Financing, Personal; Humans; Income; Malaria, Falciparum; Male; Middle Aged; Nigeria; Regression Analysis; Sesquiterpenes; Social Class; Surveys and Questionnaires | 2004 |
Global fund switches to artemisinin.
Topics: Animals; Antimalarials; Artemisinins; Drug Therapy, Combination; Fund Raising; Humans; Malaria, Falciparum; Plasmodium falciparum; Sesquiterpenes | 2004 |
Artemisinin-based combination therapy reduces expenditure on malaria treatment in KwaZulu Natal, South Africa.
Topics: Anti-Infective Agents; Antimalarials; Artemisinins; Cost Savings; Decision Trees; Drug Costs; Drug Therapy, Combination; Ethanolamines; Fluorenes; Health Expenditures; Humans; Lumefantrine; Malaria, Falciparum; Sesquiterpenes; South Africa | 2004 |
Quinine based combination therapy (QCT): first choice!
Topics: Anti-Infective Agents; Antimalarials; Artemisinins; Drug Resistance, Multiple; Drug Therapy, Combination; Humans; Malaria, Falciparum; Quinine; Sesquiterpenes | 2004 |
Comment on: Randomized controlled trial of a traditional preparation of Artemisia annua L. (Annual Wormwood) in the treatment of malaria.
Topics: Anti-Infective Agents; Antimalarials; Artemisia annua; Artemisinins; Drug Resistance; Drugs, Chinese Herbal; Humans; Malaria, Falciparum; Phytotherapy; Sesquiterpenes | 2004 |
Shortfall in front-line antimalarial drug likely in 2005.
Topics: Animals; Antimalarials; Artemisinins; Drug Design; Drug Industry; Humans; Malaria, Falciparum; Sesquiterpenes | 2005 |
Surge in demand leads to shortage of artemisinin-based combination therapy for malaria.
Topics: Antimalarials; Artemisinins; Drug Combinations; Humans; Malaria, Falciparum; Sesquiterpenes; World Health Organization | 2005 |
The benefits of artemisinin combination therapy for malaria extend beyond the individual patient.
Topics: Animals; Anti-Infective Agents; Artemisinins; Drug Therapy, Combination; Gametogenesis; Health Policy; Humans; Malaria, Falciparum; Plasmodium falciparum; Public Health; Sesquiterpenes | 2005 |
Artemisinin resistance: how can we find it?
Topics: Animals; Anti-Infective Agents; Antimalarials; Artemisinins; Drug Resistance; Malaria, Falciparum; Plasmodium falciparum; Sesquiterpenes | 2005 |
Adoption of the new antimalarial drug policy in Tanzania--a cross-sectional study in the community.
Topics: Antimalarials; Artemisinins; Child, Preschool; Chloroquine; Cross-Sectional Studies; Drug Combinations; Drug Therapy, Combination; Female; Focus Groups; Health Knowledge, Attitudes, Practice; Health Policy; Humans; Malaria, Falciparum; Male; Patient Acceptance of Health Care; Population Surveillance; Pyrimethamine; Rural Health; Self Administration; Sesquiterpenes; Sulfadoxine; Tanzania | 2005 |
Emergency measures against malaria in Niger.
Topics: Antimalarials; Artemisinins; Bedding and Linens; Child, Preschool; Drug Therapy, Combination; Humans; Infant; Infant, Newborn; Insecticides; Malaria, Falciparum; Niger; Nutrition Disorders; Sesquiterpenes; World Health Organization | 2005 |
Imported quinine resistant Plasmodium falciparum malaria in Sri Lanka.
Topics: Animals; Artemisinins; Drug Resistance; Follow-Up Studies; Humans; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Quinine; Risk Assessment; Sesquiterpenes; Severity of Illness Index; Sri Lanka; Travel; Treatment Outcome | 2005 |
Diagnosis and management of malaria in children: recommendations and IAP plan of action.
Topics: Animals; Anti-Infective Agents; Antigens, Protozoan; Antimalarials; Artemisinins; Child; Humans; Malaria, Falciparum; Plasmodium falciparum; Quinine; Sesquiterpenes | 2005 |
Artemisone--a highly active antimalarial drug of the artemisinin class.
Topics: Animals; Anti-Infective Agents; Antimalarials; Artemisia; Artemisinins; Brain; Cell Survival; Cells, Cultured; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats; Sesquiterpenes; Stem Cells | 2006 |
Emergence and clearance of gametocytes in uncomplicated Plasmodium falciparum malaria.
Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Child; Child, Preschool; Female; Gametogenesis; Humans; Malaria, Falciparum; Male; Middle Aged; Parasitemia; Plasmodium falciparum; Retrospective Studies; Sesquiterpenes | 2006 |
Production of the antimalarial drug precursor artemisinic acid in engineered yeast.
Topics: Animals; Antimalarials; Artemisia annua; Artemisinins; Bioreactors; Cytochrome P-450 Enzyme System; Drug Costs; Fermentation; Gas Chromatography-Mass Spectrometry; Genetic Engineering; Malaria, Falciparum; Mevalonic Acid; Molecular Sequence Data; Plasmodium falciparum; Saccharomyces cerevisiae; Sesquiterpenes | 2006 |
[Malaria: a medical and economic problem].
Topics: Anti-Infective Agents; Antimalarials; Artemisinins; Atovaquone; Chloroquine; Drug Combinations; Drug Resistance; Ethanolamines; Fluorenes; Health Care Costs; Humans; Lumefantrine; Malaria, Falciparum; Naphthoquinones; Proguanil; Sesquiterpenes; Survival Rate; World Health Organization | 2006 |
Decreasing pfmdr1 copy number in plasmodium falciparum malaria heightens susceptibility to mefloquine, lumefantrine, halofantrine, quinine, and artemisinin.
Topics: Animals; Antimalarials; Artemisinins; ATP-Binding Cassette Transporters; DNA, Protozoan; Drug Resistance, Multiple; Ethanolamines; Fluorenes; Genes, MDR; Inhibitory Concentration 50; Lumefantrine; Malaria, Falciparum; Mefloquine; Parasitic Sensitivity Tests; Phenanthrenes; Plasmodium falciparum; Polymerase Chain Reaction; Protozoan Proteins; Quinine; Sesquiterpenes | 2006 |
From chloroquine to artemisinin-based combination therapy: the Sudanese experience.
Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Fluorenes; Health Policy; Humans; Lumefantrine; Malaria, Falciparum; Product Surveillance, Postmarketing; Pyrimethamine; Sesquiterpenes; Sudan; Sulfadoxine; Time Factors | 2006 |
Mechanism of antimalarial action of the synthetic trioxolane RBX11160 (OZ277).
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Calcium-Transporting ATPases; Heterocyclic Compounds, 1-Ring; Malaria, Falciparum; Microscopy, Confocal; Peroxides; Plasmodium falciparum; Sesquiterpenes; Spiro Compounds | 2007 |
Preparation of a novel monoclonal antibody against the antimalarial drugs, artemisinin and artesunate.
Topics: Animals; Antibodies, Monoclonal; Antimalarials; Artemisia annua; Artemisinins; Artesunate; Enzyme-Linked Immunosorbent Assay; Malaria, Falciparum; Male; Mice; Mice, Inbred BALB C; Phytotherapy; Plasmodium falciparum; Sesquiterpenes | 2007 |
Artemisinin and sesquiterpene precursors in dead and green leaves of Artemisia annua L. crops.
Topics: Animals; Antimalarials; Artemisia annua; Artemisinins; Malaria, Falciparum; Phytotherapy; Plant Leaves; Plasmodium falciparum; Sesquiterpenes | 2007 |
Resistance to artemisinin derivatives along the Thai-Cambodian border.
Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Cambodia; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Sesquiterpenes; Thailand | 2007 |
Combating malaria. Malaria treatment: ACT two.
Topics: Africa; Antimalarials; Artemisinins; Drug Costs; Drug Industry; Drug Therapy, Combination; Health Policy; Humans; Malaria, Falciparum | 2007 |
Impact of artemisinin-based combination therapy and insecticide-treated nets on malaria burden in Zanzibar.
Topics: Adolescent; Animals; Artemisinins; Bedding and Linens; Child; Child, Preschool; Cross-Sectional Studies; Drug Therapy, Combination; Female; Humans; Infant; Infant, Newborn; Insecticides; Malaria, Falciparum; Male; Mosquito Control; Parasitemia; Plasmodium falciparum; Prevalence; Tanzania | 2007 |
Baseline in vitro efficacy of ACT component drugs on Plasmodium falciparum clinical isolates from Mali.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance, Microbial; Enzyme-Linked Immunosorbent Assay; Genetic Markers; Malaria, Falciparum; Mali; Parasitic Sensitivity Tests; Plasmodium falciparum | 2008 |
In vitro evaluations of antimalarial drugs and their relevance to clinical outcomes.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance, Microbial; Global Health; Humans; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum | 2008 |
Cost of increasing access to artemisinin combination therapy: the Cambodian experience.
Topics: Animals; Antimalarials; Artemisinins; Cambodia; Costs and Cost Analysis; Drug Therapy, Combination; Humans; Malaria, Falciparum; Mefloquine | 2008 |
Serum concentrations of MIP-1 alpha and interleukin-8 in patients suffering from acute Plasmodium falciparum malaria.
Topics: Adolescent; Adult; Aged; Anemia; Artemisinins; Artesunate; Blood; Body Temperature; Chemokine CCL3; Chemokine CCL4; Cytokines; Enzyme-Linked Immunosorbent Assay; Female; Hematocrit; Humans; Interleukin-8; Macrophage Inflammatory Proteins; Malaria, Falciparum; Male; Middle Aged; Monokines; Sesquiterpenes; Thailand | 1995 |
The infectivity of gametocytes of Plasmodium falciparum from patients treated with artemisinin.
Topics: Animals; Antimalarials; Artemisinins; Humans; Malaria, Falciparum; Plasmodium falciparum; Sesquiterpenes | 1994 |
Activity of azithromycin as a blood schizonticide against rodent and human plasmodia in vivo.
Topics: Administration, Oral; Animals; Antimalarials; Aotus trivirgatus; Artemisinins; Azithromycin; Disease Models, Animal; Doxycycline; Drug Therapy, Combination; Humans; Injections, Subcutaneous; Malaria; Malaria, Falciparum; Mice; Parasitemia; Phenanthrenes; Plasmodium berghei; Quinine; Sesquiterpenes | 1995 |
Early treatment of malaria in the community using artemisinin--hope or hazard?
Topics: Adult; Antimalarials; Antiprotozoal Agents; Artemisinins; Child; Community Health Services; Drug Resistance; Humans; Malaria, Falciparum; Rural Health; Sesquiterpenes | 1994 |
Clinical trials of artemisinin and its derivatives in the treatment of malaria in China.
Topics: Antimalarials; Antiprotozoal Agents; Artemisinins; Artesunate; China; Clinical Trials as Topic; Humans; Injections, Intramuscular; Injections, Intravenous; Malaria, Cerebral; Malaria, Falciparum; Sesquiterpenes; Suppositories; Tablets | 1994 |
Artemisinin compounds in treatment of malaria.
Topics: Adult; Antimalarials; Artemisinins; Artesunate; Cambodia; Drug Approval; Drug Resistance; Humans; Malaria, Falciparum; Male; Military Personnel; Netherlands; Phenanthrenes; Sesquiterpenes | 1993 |
New, antimalarial, tricyclic 1,2,4-trioxanes: evaluations in mice and monkeys.
Topics: Animals; Antimalarials; Aotus trivirgatus; Artemisinins; Bridged-Ring Compounds; Heterocyclic Compounds; Malaria; Malaria, Falciparum; Mice; Molecular Structure; Plasmodium berghei; Sesquiterpenes | 1994 |
The interaction of artemisinin with malarial hemozoin.
Topics: Animals; Antimalarials; Artemisinins; Biological Transport, Active; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Drugs, Chinese Herbal; Hemeproteins; Humans; In Vitro Techniques; Malaria, Falciparum; Plasmodium falciparum; Sesquiterpenes | 1994 |
Treatment of malaria in Vietnam with oral artemisinin.
Topics: Administration, Oral; Adult; Antimalarials; Artemisinins; Capsules; Child; Humans; Malaria, Falciparum; Malaria, Vivax; Retrospective Studies; Sesquiterpenes; Tablets; Vietnam | 1993 |
[Qinghaosu (artemisinine), Chinese herb against multi-resistant malaria parasite; also important for The Netherlands].
Topics: Animals; Antimalarials; Artemisinins; Drug Resistance; Drugs, Chinese Herbal; Humans; Malaria, Falciparum; Plasmodium falciparum; Sesquiterpenes | 1993 |
Iron-dependent free radical generation from the antimalarial agent artemisinin (qinghaosu).
Topics: Animals; Antimalarials; Artemisinins; Drugs, Chinese Herbal; Erythrocyte Deformability; Free Radicals; Iron; Iron Chelating Agents; Malaria, Falciparum; Male; Mice; Plasmodium falciparum; Sesquiterpenes | 1993 |
A closer look at malaria in India.
Topics: Animals; Antimalarials; Artemisinins; Drug Resistance; Humans; India; Malaria, Falciparum; Plasmodium falciparum; Sesquiterpenes | 1996 |
In vitro stage-specific sensitivity of Plasmodium falciparum to quinine and artemisinin drugs.
Topics: Adult; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Drug Evaluation, Preclinical; Drug Resistance; Humans; In Vitro Techniques; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Quinine; Sesquiterpenes | 1996 |
Serum laminin and basic fibroblast growth factor concentrations in patients with complicated Plasmodium falciparum malaria.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Artesunate; Fibroblast Growth Factor 2; Humans; Kinetics; Laminin; Malaria, Falciparum; Mefloquine; Middle Aged; Sesquiterpenes | 1996 |
The pharmacokinetics of a single dose of artemisinin in patients with uncomplicated falciparum malaria.
Topics: Adult; Antimalarials; Artemisinins; Humans; Malaria, Falciparum; Sesquiterpenes | 1997 |
Artesunate and cerebellar dysfunction in falciparum malaria.
Topics: Adult; Antimalarials; Artemisinins; Artesunate; Cerebellar Diseases; Humans; Malaria, Falciparum; Male; Sesquiterpenes | 1997 |
Delayed parasite clearance in a splenectomized patient with falciparum malaria who was treated with artemisinin derivatives.
Topics: Adult; Animals; Antimalarials; Artemisinins; Humans; Malaria, Falciparum; Male; Plasmodium falciparum; Sesquiterpenes; Splenectomy | 1997 |
Measurement of serum nitrite/nitrate concentrations using high-performance liquid chromatography.
Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Artesunate; Child; Chromatography, High Pressure Liquid; Circadian Rhythm; Cohort Studies; Humans; Malaria, Falciparum; Middle Aged; Nitrates; Nitrites; Reference Values; Reproducibility of Results; Sensitivity and Specificity; Sesquiterpenes; Time Factors | 1998 |
Artemisinin population pharmacokinetics in children and adults with uncomplicated falciparum malaria.
Topics: Administration, Oral; Adolescent; Adult; Antimalarials; Artemisinins; Child; Child, Preschool; Female; Half-Life; Humans; Malaria, Falciparum; Male; Middle Aged; Models, Biological; Sesquiterpenes | 1998 |
Follow-up of the susceptibility of Plasmodium falciparum to antimalarials in Gabon.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Dose-Response Relationship, Drug; Drug Resistance; Follow-Up Studies; Gabon; Malaria, Falciparum; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Sesquiterpenes; Sulfadoxine | 1998 |
The rational use of qinghaosu and its derivatives in the treatment of malaria in 1998.
Topics: Antimalarials; Artemisinins; Chemistry, Pharmaceutical; Drug Resistance; Evidence-Based Medicine; Humans; Malaria, Falciparum; Sesquiterpenes; Therapeutic Equivalency | 1998 |
In vitro susceptibility of African Plasmodium falciparum isolates to dihydroartemisinin and the risk factors for resistance to qinghaosu.
Topics: Africa; Animals; Antimalarials; Artemisinins; Chloroquine; Cross Reactions; Drug Evaluation, Preclinical; Drug Resistance; France; Humans; Malaria, Falciparum; Mefloquine; Phenanthrenes; Plasmodium falciparum; Sesquiterpenes; Travel | 1998 |
Antimalarial drug resistance and combination chemotherapy.
Topics: Animals; Antimalarials; Artemisinins; Atovaquone; Chloroquine; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Mefloquine; Naphthoquinones; Plasmodium falciparum; Sesquiterpenes | 1999 |
Averting a malaria disaster.
Topics: Animals; Antimalarials; Artemisinins; Costs and Cost Analysis; Drug Resistance; Drug Therapy, Combination; Drugs, Chinese Herbal; Humans; Malaria, Falciparum; Pyrimethamine; Sesquiterpenes; Sulfadoxine | 1999 |
Risk factors for gametocyte carriage in uncomplicated falciparum malaria.
Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Carrier State; Child; Child, Preschool; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Multivariate Analysis; Parasitemia; Phenanthrenes; Plasmodium falciparum; Prospective Studies; Quinine; Regression Analysis; Risk Factors; Seroepidemiologic Studies; Sesquiterpenes; Thailand | 1999 |
Artemisinin and its derivatives are transported by a vacuolar-network of Plasmodium falciparum and their anti-malarial activities are additive with toxic sphingolipid analogues that block the network.
Topics: Animals; Antimalarials; Artemisinins; Biological Transport; Chloroquine; Drug Resistance; Drug Synergism; Erythrocytes; Fluorescent Antibody Technique, Indirect; Humans; Malaria, Falciparum; Membrane Proteins; Microscopy, Electron; Plasmodium falciparum; Protozoan Proteins; Sesquiterpenes; Sphingolipids; Vacuoles | 1999 |
Inoculum effect leads to overestimation of in vitro resistance for artemisinin derivatives and standard antimalarials: a Gambian field study.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Gambia; Hematocrit; Humans; Malaria, Falciparum; Mefloquine; Parasitemia; Phenanthrenes; Plasmodium falciparum; Quinine; Scintillation Counting; Sensitivity and Specificity; Sesquiterpenes | 1999 |
Ptyalism as a side effect in the treatment of falciparum malaria with artemisinin.
Topics: Antimalarials; Artemisinins; Humans; Malaria, Falciparum; Sesquiterpenes; Sialorrhea | 1999 |
Serum concentrations of granulocyte-colony stimulating factor in complicated Plasmodium falciparum malaria.
Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Artesunate; Calcitonin; Calcitonin Gene-Related Peptide; Chemokine CCL4; Child; Enzyme-Linked Immunosorbent Assay; Erythrocytes; Erythropoietin; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Macrophage Inflammatory Proteins; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Nitrates; Plasmodium falciparum; Protein Precursors; Reference Values; Sesquiterpenes; Stem Cell Factor | 2000 |
Influence of hemoglobin E trait on the antimalarial effect of artemisinin derivatives.
Topics: Adult; Antimalarials; Artemisinins; Case-Control Studies; Female; Hemoglobin E; Humans; Malaria, Falciparum; Male; Retrospective Studies; Sesquiterpenes | 2000 |
Searching for antimalarials in plants.
Topics: Animals; Antimalarials; Artemisia; Artemisinins; Drug Resistance; Flavonoids; Humans; Malaria, Falciparum; Photography; Phytotherapy; Plant Extracts; Plants, Medicinal; Plasmodium vivax; Sesquiterpenes; Vietnam | 2000 |
The tyrosine-86 allele of the pfmdr1 gene of Plasmodium falciparum is associated with increased sensitivity to the anti-malarials mefloquine and artemisinin.
Topics: Alleles; Animals; Antimalarials; Artemisinins; ATP-Binding Cassette Transporters; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Protozoan Proteins; Sesquiterpenes; Tetrahydrofolate Dehydrogenase; Tyrosine | 2000 |
Determination of failure of treatment of plasmodium falciparum infection by using polymerase chain reaction single-strand conformational polymorphism fingerprinting.
Topics: Animals; Antimalarials; Artemisinins; Humans; Malaria, Falciparum; Merozoite Surface Protein 1; Plasmodium falciparum; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Protozoan Proteins; Sensitivity and Specificity; Sesquiterpenes; Treatment Failure | 1999 |
In vitro and in vivo potentiation of artemisinin and synthetic endoperoxide antimalarial drugs by metalloporphyrins.
Topics: Animals; Antimalarials; Artemisinins; Cell Line; Chloroquine; Drug Resistance; Drug Synergism; Humans; Malaria, Falciparum; Metalloporphyrins; Mice; Peroxides; Plasmodium falciparum; Sesquiterpenes | 2000 |
Use of saliva and capillary blood samples as substitutes for venous blood sampling in pharmacokinetic investigations of artemisinin.
Topics: Adolescent; Adult; Antimalarials; Area Under Curve; Artemisinins; Capillaries; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Humans; Malaria, Falciparum; Male; Middle Aged; Randomized Controlled Trials as Topic; Regression Analysis; Saliva; Sesquiterpenes; Veins | 2000 |
Guideline in management of severe malaria.
Topics: Antimalarials; Artemisinins; Humans; Malaria, Falciparum; Practice Guidelines as Topic; Quinine; Sesquiterpenes | 2000 |
Emerging resistance of Plasmodium falciparum to artemisinine and related compounds.
Topics: Adult; Animals; Antimalarials; Artemisinins; Drug Resistance; Humans; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Sesquiterpenes | 2000 |
Malaria epidemic in Burundi.
Topics: Antimalarials; Artemisinins; Burundi; Chloroquine; Disease Outbreaks; Drug Therapy, Combination; Humans; Malaria, Falciparum; Sesquiterpenes | 2001 |
Radical mechanism of action of the artemisinin-type compounds.
Topics: Animals; Antimalarials; Artemisinins; Humans; Malaria, Falciparum; Plasmodium falciparum; Sesquiterpenes | 2001 |
Is there any artemisinin resistance in falciparum malaria?
Topics: Animals; Antimalarials; Artemisinins; Dose-Response Relationship, Drug; Drug Resistance; Humans; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Sesquiterpenes; Treatment Outcome | 2000 |
Chlorproguanil-dapsone (LAPDAP) for uncomplicated falciparum malaria.
Topics: Antimalarials; Artemisinins; Clinical Trials, Phase III as Topic; Dapsone; Drug Approval; Drug Combinations; Drug Therapy, Combination; Health Services Accessibility; Humans; Malaria, Falciparum; Proguanil; Sesquiterpenes | 2001 |