Page last updated: 2024-08-25

artemether and Disease Models, Animal

artemether has been researched along with Disease Models, Animal in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (8.57)18.2507
2000's12 (34.29)29.6817
2010's19 (54.29)24.3611
2020's1 (2.86)2.80

Authors

AuthorsStudies
Amewu, R; Bongard, E; Charnaud, S; Davies, J; Ellis, GL; Gargallo, D; Gibbons, P; Hall, C; Jesús, M; Lozanom, S; O'Neill, PM; Rimmer, K; Sabbani, S; Shone, A; Stanford, D; Stocks, PA; Vivas, L; Ward, SA1
Gille, L; Machín, L; Monzote, L; Nápoles, R1
Antunes, LR; Grabe-Guimarães, A; Guimarães, HN; Mosqueira, VCF; Richard, S; Silveira, APA; Souza, ACM1
Hu, B; Meng, J; Shi, Z; Wu, H; Yan, S; Yang, Y; Zhao, X; Zhou, C; Zhou, X1
Chen, A; Jia, Y; Li, M; Shao, J; Wang, F; Wang, L; Zhang, F; Zhang, Z; Zheng, S1
Abd El-Mageed, SA; Abdalla, HA; El-Beshbishi, SN; El-Nemr, HEE; Saleh, NE; Shebl, AM; Taman, A1
El-Lakkany, NM; Seif El-Din, SH1
Anderson, L; Bond, V; Liu, M; Patrickson, J; Pitts, S; Solomon, W; Stiles, JK; Wilson, NO1
Pathak, S; Patil, S; Patravale, V; Sharma, S; Suryavanshi, S1
Dai, JR; Ji, Y; Li, HJ; Li, TY; Liang, YS; Qian, YL; Qu, GL; Wang, W1
Anderson, L; Ford, BD; Liu, M; Patrickson, J; Pitts, S; Solomon, W; Stiles, JK; Wilson, NO1
Abiodun, OO; Akinbo, J; Ojurongbe, O1
Cabrales, P; Carvalho, LJ; Kuypers, FA; Oronsky, B; Scicinski, J; Yalcin, O1
Brennan, GP; Fairweather, I; Halferty, L; Hanna, RE; Johnston, RC; O'Neill, JF1
Avolio, F; Baburin, I; Barbieux, C; Bennett, KL; Berishvili, E; Bock, C; Briand, F; Casteels, T; Colinge, J; Collombat, P; Courtney, M; Distel, M; Farlik, M; Frogne, T; Gridling, M; Harkany, T; Hecksher-Sørensen, J; Hering, S; Honoré, C; Huber, KVM; Ingvorsen, C; Kimmel, RA; Klughammer, J; Kubicek, S; Lardeau, CH; Li, J; Májek, P; Meyer, D; Parapatics, K; Pauler, FM; Penz, T; Romanov, RA; Schmitner, N; Sdelci, S; Spittler, A; Stukalov, A; Sturtzel, C; Sulpice, T; Superti-Furga, G; Vieira, A1
Clark, RL; DeLise, AM; Youreneff, M1
Sullivan, DJ; Walker, LA1
Hong, SJ; Hong, ST; Keiser, J; Kim, TI; Li, S; Yoo, WG1
Jiao, PY; Mei, JY; Xiao, SH1
Abdul-Ghani, R; Hassan, A; Loutfy, N; Sheta, M1
Dai, JR; Li, HJ; Li, YZ; Liang, YS; Qu, GL; Tao, YH; Wang, W; Wei, JY; Xing, YT1
Joshi, M; Pathak, S; Patil, S; Patravale, V; Sharma, S1
Cai, Y; Chollet, J; Tanner, M; Utzinger, J; Xiao, SH; Yao, JM1
Amato Neto, V; Boulos, M; Canhassi, RR; Chieffi, PP; Lescano, SZ1
Arai, M; Ishii, A; Matsuoka, H1
Cuzzocrea, S; Di Paola, R; Mirshafiey, A; Saadat, F1
Keiser, J; Shu-Hua, X; Tanner, M; Utzinger, J1
Jian, X; Keiser, J; Odermatt, P; Shu-Hua, X; Tanner, M; Tesana, S; Utzinger, J; Zhen-San, C1
Chollet, J; Santo-Tomas, J; Scheurer, C; Snyder, C; Wittlin, S1
Fu, YF; Li, Y; Ni, J; Shi, LP; Tang, W; Wan, J; Wang, JX; Yang, YF; Zhou, R; Zuo, JP1
Brennan, G; Dong, Y; Fairweather, I; Keiser, J; Utzinger, J; Vennerstrom, JL1
Chen, YD; Lin, BY; Pan, YR; Tang, WZ; Xu, B; Zhang, JX; Zheng, H1
Fang, Y; Lin, BY; Pan, YR; Zhang, JX; Zheng, H1
Ager, AL; Canfield, CJ; Heiffer, MH; Klayman, DL; Kyle, DE; Milhous, WK; Rossan, RN; Schuster, BG; Shmuklarsky, MJ; Tang, DB1
Chollet, J; Mei, J; Tanner, M; Utzinger, J; Xiao, S; You, J1

Other Studies

35 other study(ies) available for artemether and Disease Models, Animal

ArticleYear
Two-step synthesis of achiral dispiro-1,2,4,5-tetraoxanes with outstanding antimalarial activity, low toxicity, and high-stability profiles.
    Journal of medicinal chemistry, 2008, Apr-10, Volume: 51, Issue:7

    Topics: Animals; Antimalarials; Chlorocebus aethiops; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Stability; Humans; Male; Mice; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Rats; Salmonella typhimurium; Spiro Compounds; Stereoisomerism; Structure-Activity Relationship; Tetraoxanes

2008
Leishmania amazonensis response to artemisinin and derivatives.
    Parasitology international, 2021, Volume: 80

    Topics: Animals; Artemether; Artemisinins; Artesunate; Disease Models, Animal; Female; Leishmania mexicana; Mice; Mice, Inbred BALB C; Parasite Load; Trypanocidal Agents

2021
Reduced cardiotoxicity and increased oral efficacy of artemether polymeric nanocapsules in Plasmodium berghei-infected mice.
    Parasitology, 2018, Volume: 145, Issue:8

    Topics: Administration, Oral; Animals; Antimalarials; Artemether; Cardiotoxicity; Disease Models, Animal; Electrocardiography; Female; Malaria; Male; Mice; Mice, Inbred C57BL; Nanocapsules; Plasmodium berghei

2018
Artemether attenuates LPS-induced inflammatory bone loss by inhibiting osteoclastogenesis and bone resorption via suppression of MAPK signaling pathway.
    Cell death & disease, 2018, 05-01, Volume: 9, Issue:5

    Topics: Animals; Artemether; Bone Density Conservation Agents; Bone Remodeling; Disease Models, Animal; Gene Expression Regulation; Lipopolysaccharides; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Osteoclasts; Osteogenesis; Osteolysis; RANK Ligand; RAW 264.7 Cells

2018
P53-dependent induction of ferroptosis is required for artemether to alleviate carbon tetrachloride-induced liver fibrosis and hepatic stellate cell activation.
    IUBMB life, 2019, Volume: 71, Issue:1

    Topics: Animals; Apoptosis; Artemether; Carbon Tetrachloride; Cell Death; Cell Proliferation; Disease Models, Animal; Ferroptosis; Hepatic Stellate Cells; Humans; Iron Overload; Lipid Peroxidation; Liver Cirrhosis; Mice; RNA, Small Interfering; Signal Transduction; Tumor Suppressor Protein p53

2019
Effect of omega-3 fatty acids administered as monotherapy or combined with artemether on experimental Schistosoma mansoni infection.
    Acta tropica, 2019, Volume: 194

    Topics: Africa South of the Sahara; Animals; Artemether; Disease Models, Animal; Drug Combinations; Fatty Acids, Omega-3; Female; Mice; Mice, Inbred BALB C; Schistosoma mansoni; Schistosomiasis; Schistosomicides

2019
Haemin enhances the in vivo efficacy of artemether against juvenile and adult Schistosoma mansoni in mice.
    Parasitology research, 2013, Volume: 112, Issue:5

    Topics: Animals; Antioxidants; Artemether; Artemisinins; Disease Models, Animal; Drug Synergism; Hemin; Male; Mice; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides; Treatment Outcome

2013
Pharmacologic inhibition of CXCL10 in combination with anti-malarial therapy eliminates mortality associated with murine model of cerebral malaria.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: Animals; Antimalarials; Apoptosis; Artemether; Artemisinins; Atorvastatin; Blood-Brain Barrier; Caspases; Cell Count; Chemokine CXCL10; Disease Models, Animal; Drug Interactions; Endothelial Cells; Gene Expression Regulation; Heme Oxygenase-1; Heptanoic Acids; Humans; Leukocytes; Malaria, Cerebral; Membrane Proteins; Mice; Mice, Inbred C57BL; Models, Molecular; Neuroglia; Nucleic Acid Conformation; Pyrroles; Survival Analysis

2013
Evaluation of novel lipid based formulation of β-Artemether and Lumefantrine in murine malaria model.
    International journal of pharmaceutics, 2013, Oct-15, Volume: 455, Issue:1-2

    Topics: Animals; Antimalarials; Artemether; Artemisinins; Chemistry, Pharmaceutical; Disease Models, Animal; Ethanolamines; Fluorenes; Lipids; Lumefantrine; Malaria; Male; Mice; Parasitemia; Plasmodium berghei

2013
Efficacy of artemether and artesunate in mice infected with praziquantel non-susceptible isolate of Schistosoma japonicum.
    Parasitology research, 2014, Volume: 113, Issue:3

    Topics: Administration, Oral; Animals; Artemether; Artemisinins; Artesunate; Disease Models, Animal; Drug Resistance; Female; Mice; Mice, Inbred ICR; Praziquantel; Schistosoma japonicum; Schistosomiasis japonica; Schistosomicides

2014
Neuregulin-1 attenuates mortality associated with experimental cerebral malaria.
    Journal of neuroinflammation, 2014, Jan-17, Volume: 11

    Topics: Animals; Antimalarials; Artemether; Artemisinins; Behavior, Animal; Blood-Brain Barrier; Brain; Cytokines; Disease Models, Animal; Encephalitis; Endothelium; Leukocytes; Malaria, Cerebral; Mice; Mice, Inbred C57BL; Neuregulin-1; Neuroprotective Agents; Plasmodium berghei

2014
The effect of lopinavir/ritonavir on the antimalarial activity of artemether or artemether/lumefantrine in a mouse model of Plasmodium berghei.
    Journal of chemotherapy (Florence, Italy), 2015, Volume: 27, Issue:1

    Topics: Animals; Anti-Retroviral Agents; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Coinfection; Disease Models, Animal; Drug Combinations; Drug Interactions; Ethanolamines; Fluorenes; HIV Infections; Lopinavir; Malaria; Mice; Plasmodium berghei; Ritonavir

2015
From METS to malaria: RRx-001, a multi-faceted anticancer agent with activity in cerebral malaria.
    Malaria journal, 2015, May-28, Volume: 14

    Topics: Animals; Antimalarials; Artemether; Artemisinins; Azetidines; Carboxylic Ester Hydrolases; Disease Models, Animal; Drug Combinations; Glucosephosphate Dehydrogenase; Humans; Malaria, Cerebral; Mice; Mice, Inbred C57BL; Motor Activity; Nitro Compounds; Parasitemia; Plasmodium berghei

2015
Disruption of spermatogenesis in the liver fluke, Fasciola hepatica by two artemisinin derivatives, artemether and artesunate.
    Journal of helminthology, 2017, Volume: 91, Issue:1

    Topics: Administration, Oral; Animals; Anti-Infective Agents; Apoptosis; Artemether; Artemisinins; Artesunate; Cell Count; Cell Survival; Disease Models, Animal; Fasciola hepatica; Fascioliasis; Histocytochemistry; Male; Microscopy, Electron, Transmission; Mitochondria; Rats; Spermatogenesis; Spermatozoa; Time Factors

2017
Artemisinins Target GABA
    Cell, 2017, Jan-12, Volume: 168, Issue:1-2

    Topics: Animals; Artemether; Artemisinins; Carrier Proteins; Cell Transdifferentiation; Cells, Cultured; Diabetes Mellitus; Diabetes Mellitus, Type 1; Disease Models, Animal; gamma-Aminobutyric Acid; Gene Expression Profiling; Homeodomain Proteins; Humans; Insulin; Islets of Langerhans; Membrane Proteins; Mice; Protein Stability; Rats; Receptors, GABA-A; Signal Transduction; Single-Cell Analysis; Transcription Factors; Zebrafish

2017
Developmental toxicity studies of lumefantrine and artemether in rats and rabbits.
    Birth defects research. Part B, Developmental and reproductive toxicology, 2016, Volume: 107, Issue:6

    Topics: Animals; Antimalarials; Artemether; Artemisinins; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Embryonic Development; Ethanolamines; Female; Fetal Development; Fluorenes; Lumefantrine; Malaria, Falciparum; Male; Maternal Exposure; Pregnancy; Rabbits; Rats; Rats, Sprague-Dawley; Toxicity Tests; Toxicokinetics

2016
Impact of Extended Duration of Artesunate Treatment on Parasitological Outcome in a Cytocidal Murine Malaria Model.
    Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:4

    Topics: Amodiaquine; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Disease Models, Animal; Female; Malaria; Mice; Mice, Inbred BALB C; Quinolines

2017
Efficacy of artesunate and artemether against Clonorchis sinensis in rabbits.
    Parasitology research, 2009, Volume: 106, Issue:1

    Topics: Administration, Oral; Animals; Anthelmintics; Artemether; Artemisinins; Artesunate; Bile Ducts; Clonorchiasis; Clonorchis sinensis; Disease Models, Animal; Praziquantel; Rabbits

2009
Effect of mefloquine administered orally at single, multiple, or combined with artemether, artesunate, or praziquantel in treatment of mice infected with Schistosoma japonicum.
    Parasitology research, 2011, Volume: 108, Issue:2

    Topics: Administration, Oral; Animals; Artemether; Artemisinins; Artesunate; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Female; Mefloquine; Mice; Mice, Inbred Strains; Parasitic Diseases, Animal; Parasitic Sensitivity Tests; Praziquantel; Schistosoma japonicum; Schistosomiasis japonica; Schistosomicides; Treatment Outcome

2011
Artemether shows promising female schistosomicidal and ovicidal effects on the Egyptian strain of Schistosoma mansoni after maturity of infection.
    Parasitology research, 2011, Volume: 108, Issue:5

    Topics: Animals; Anthelmintics; Artemether; Artemisinins; Disease Models, Animal; Egypt; Female; Intestines; Liver; Mice; Parasite Egg Count; Schistosoma mansoni; Schistosomiasis mansoni; Treatment Outcome

2011
Effects of artemether, artesunate and dihydroartemisinin administered orally at multiple doses or combination in treatment of mice infected with Schistosoma japonicum.
    Parasitology research, 2011, Volume: 109, Issue:2

    Topics: Administration, Oral; Animals; Antiprotozoal Agents; Artemether; Artemisinins; Artesunate; Disease Models, Animal; Female; Mice; Rodent Diseases; Schistosoma japonicum; Schistosomiasis japonica; Treatment Outcome

2011
Intravenous β-artemether formulation (ARM NLC) as a superior alternative to commercial artesunate formulation.
    The Journal of antimicrobial chemotherapy, 2012, Volume: 67, Issue:11

    Topics: Administration, Intravenous; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Disease Models, Animal; Malaria; Male; Mice; Parasitemia; Plasmodium berghei; Treatment Outcome

2012
Selection and reversal of Plasmodium berghei resistance in the mouse model following repeated high doses of artemether.
    Parasitology research, 2004, Volume: 92, Issue:3

    Topics: Animals; Antimalarials; Artemether; Artemisinins; Disease Models, Animal; Drug Resistance; Female; Immunity, Innate; Malaria; Male; Mice; Mice, Inbred Strains; Naphthyridines; Plasmodium berghei; Sesquiterpenes

2004
[Antischistosomal activity of artemether in experimental Schistosomiasis mansoni].
    Revista de saude publica, 2004, Volume: 38, Issue:1

    Topics: Animals; Artemether; Artemisinins; Disease Models, Animal; Feces; Female; Mice; Mice, Inbred BALB C; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides; Sesquiterpenes

2004
Laboratory evaluation of the ict malaria P.f./P.v. immunochromatographic test for detecting the panmalarial antigen using a rodent malaria model.
    The American journal of tropical medicine and hygiene, 2004, Volume: 70, Issue:2

    Topics: Animals; Antigens, Protozoan; Antimalarials; Artemether; Artemisinins; Chromatography; Disease Models, Animal; False Negative Reactions; False Positive Reactions; Female; Fructose-Bisphosphate Aldolase; Malaria; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Parasitemia; Plasmodium berghei; Plasmodium falciparum; Plasmodium vivax; Reagent Kits, Diagnostic; Sensitivity and Specificity; Sesquiterpenes

2004
Artemether: a new therapeutic strategy in experimental rheumatoid arthritis.
    Immunopharmacology and immunotoxicology, 2005, Volume: 27, Issue:4

    Topics: Animals; Antibodies; Antimalarials; Antirheumatic Agents; Artemether; Artemisinins; Arthritis, Experimental; Arthritis, Rheumatoid; Bone and Bones; Cell Line, Tumor; Cell Survival; Collagen Type II; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Injections, Intramuscular; Injections, Intraperitoneal; Joints; Male; Matrix Metalloproteinase 2; Methotrexate; Mice; Nitric Oxide; Rats; Rats, Inbred Lew; Time Factors

2005
Artesunate and artemether are effective fasciolicides in the rat model and in vitro.
    The Journal of antimicrobial chemotherapy, 2006, Volume: 57, Issue:6

    Topics: Animals; Antiplatyhelmintic Agents; Artemether; Artemisinins; Artesunate; Bile Ducts; Disease Models, Animal; Fasciola hepatica; Fascioliasis; Female; Microscopy, Electron, Scanning; Rats; Rats, Wistar; Sesquiterpenes

2006
Effect of artesunate and artemether against Clonorchis sinensis and Opisthorchis viverrini in rodent models.
    International journal of antimicrobial agents, 2006, Volume: 28, Issue:4

    Topics: Animals; Artemether; Artemisinins; Artesunate; Clonorchis sinensis; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Opisthorchis; Rats; Sesquiterpenes

2006
In vitro and in vivo interaction of synthetic peroxide RBx11160 (OZ277) with piperaquine in Plasmodium models.
    Experimental parasitology, 2007, Volume: 115, Issue:3

    Topics: Animals; Antimalarials; Artemether; Artemisinins; Atovaquone; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Erythrocytes; Female; Heterocyclic Compounds, 1-Ring; Humans; Malaria; Mice; Parasitemia; Parasitic Sensitivity Tests; Peroxides; Plasmodium berghei; Plasmodium falciparum; Pyrimethamine; Quinolines; Spiro Compounds

2007
Investigation of the immunosuppressive activity of artemether on T-cell activation and proliferation.
    British journal of pharmacology, 2007, Volume: 150, Issue:5

    Topics: Animals; Artemether; Artemisinins; CD3 Complex; Cell Cycle; Cell Proliferation; Cell Survival; Concanavalin A; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Female; Hypersensitivity, Delayed; Immunity, Cellular; Immunologic Memory; Immunosuppressive Agents; Interferon-gamma; Interleukin-2; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mitogens; Ovalbumin; Phosphorylation; Proto-Oncogene Proteins c-raf; ras Proteins; T-Lymphocytes; Time Factors

2007
Activity of artemether and OZ78 against triclabendazole-resistant Fasciola hepatica.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2007, Volume: 101, Issue:12

    Topics: Adamantane; Administration, Oral; Animals; Antiplatyhelmintic Agents; Artemether; Artemisinins; Benzimidazoles; Bile Ducts; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Resistance; Fasciola hepatica; Fascioliasis; Female; Male; Rats; Rats, Sprague-Dawley; Rats, Wistar; Triclabendazole

2007
[Studies on the establishment of malarial animal model of short-term relapse. IV. Short-term relapse in rhesus monkeys infected with sporozoites of Plasmodium cynomolgi].
    Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 1993, Volume: 11, Issue:4

    Topics: Animals; Antimalarials; Artemether; Artemisinins; Chloroquine; Disease Models, Animal; Drug Therapy, Combination; Erythrocytes; Macaca mulatta; Malaria; Naphthyridines; Plasmodium cynomolgi; Recurrence; Sesquiterpenes

1993
[Studies on the establishment of malarial animal model of short-term relapse. III. Combined therapy with pyronaridine-artemether-chloroquine for parasitemia clearance].
    Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 1993, Volume: 11, Issue:3

    Topics: Animals; Antimalarials; Artemether; Artemisinins; Chloroquine; Disease Models, Animal; Drug Therapy, Combination; Macaca mulatta; Malaria; Naphthyridines; Plasmodium cynomolgi; Recurrence; Sesquiterpenes

1993
Comparison of beta-artemether and beta-arteether against malaria parasites in vitro and in vivo.
    The American journal of tropical medicine and hygiene, 1993, Volume: 48, Issue:3

    Topics: Animals; Antimalarials; Aotus trivirgatus; Artemether; Artemisinins; Chloroquine; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Malaria; Malaria, Falciparum; Male; Mefloquine; Mice; Plasmodium berghei; Plasmodium falciparum; Sesquiterpenes; Structure-Activity Relationship

1993
Effect of combined treatment with praziquantel and artemether on Schistosoma japonicum and Schistosoma mansoni in experimentally infected animals.
    Acta tropica, 2001, Sep-01, Volume: 80, Issue:1

    Topics: Administration, Oral; Animals; Anthelmintics; Artemether; Artemisinins; Cricetinae; Disease Models, Animal; Drug Therapy, Combination; Female; Male; Praziquantel; Rabbits; Schistosoma japonicum; Schistosoma mansoni; Schistosomiasis japonica; Schistosomiasis mansoni; Schistosomicides; Sesquiterpenes; Time Factors

2001