Page last updated: 2024-08-25

artemether and Cerebral Malaria

artemether has been researched along with Cerebral Malaria in 41 studies

Research

Studies (41)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	17 (41.46)	18.2507
2000's	8 (19.51)	29.6817
2010's	13 (31.71)	24.3611
2020's	3 (7.32)	2.80

Authors

Authors	Studies
Bertinaria, M; Carvalho, LJ; Frangos, JA; Fruttero, R; Gasco, A; Guglielmo, S; Hofer, A; Marini, E; Martins, YC; Orjuela-Sanchez, P; Zanini, GM	1
Amoh, G; Amuzu, DSY; Andoh, NE; Ansong, M; Hirst, J; Nyaaba, N; Ordóñez-Mena, JM	1
Ackerman, HC; Carvalho, LJ; Daniel-Ribeiro, CT; Gul, S	1
Ackerman, HC; Carvalho, LJM; Conceição, FG; Daniel-Ribeiro, CT; Gul, S; Moreira, AS; Ribeiro-Gomes, FL; Sanches, GS	1
Babu, PP; Baruah, UK; Karri, VVSR; Kuppusamy, G; Pandey, V; Praveen Kumar, S; Vanka, R	1
Effa, EE; Esu, EB; Meremikwu, MM; Opie, ON	1
Anderson, L; Bond, V; Liu, M; Patrickson, J; Pitts, S; Solomon, W; Stiles, JK; Wilson, NO	1
Carvalho, LJ; Frangos, JA; Martins, YC; Meays, D; Melchior, B; Ong, PK; Orjuela-Sánchez, P; Zanini, GM	1
Anderson, L; Ford, BD; Liu, M; Patrickson, J; Pitts, S; Solomon, W; Stiles, JK; Wilson, NO	1
Effa, EE; Esu, E; Meremikwu, MM; Opie, ON; Uwaoma, A	1
Cabrales, P; Carvalho, LJ; Kuypers, FA; Oronsky, B; Scicinski, J; Yalcin, O	1
Desruisseaux, MS; Golightly, LM; Machado, FS; Tanowitz, HB; Weiss, LM	1
Cabrales, P; Carvalho, LJ; Frangos, JA; Meays, D; Zanini, GM	1
Kano, S	1
Carvalho, LJ; Clemmer, L; Frangos, JA; Martins, YC; Zanini, GM	1
Bruno, FP; Dai, M; Desruisseaux, MS; Freeman, B; Reznik, SE; Shikani, HJ; Stephani, RA; Tanowitz, HB; Weiss, LM	1
Elhassan, SH; Ibrahim, SA; Satti, GM	1
Adam, I; Aelbasit, IA; Elbashir, MI; Idris, HM; Mohamed-Ali, AA	1
Aceng, JR; Byarugaba, JS; Tumwine, JK	1
Agbéko, F; Akpako, P; Atakouma, DY; Badayodi, A; Gbadoé, AD; Géraldo, A; Guédénon, J; Lawson-Evi, K	1
Diakite, M; Keita, MM; Konate, S; Oumar, AA; Poudiougou, B; Sall, A; Sylla, M; Togo, B	1
Bartkovjak, M; Bauer, F; Benca, J; Bukovinova, P; Dubai, A; Duris, M; Holeckova, K; Huttova, M; Ianetti, R; Kalavsky, M; Kniezova, Z; Kovac, M; Kralova, J; Kutna, K; Mykyta, Y; Ocenas, M; Ondrusova, A; Pivarnik, M; Seckova, S; Shahum, A; Taziarova, M; Uhercik, L; Vilmova, M	1
Adamcova, J; Benca, J; Ondrusova, A; Polonova, J; Takacova, M; Taziarova, M	1
Boecken, GH; Lademann, M	1
Adio, R; Oduola, AM; Omokhodion, SJ; Salako, LA; Sowunmi, A; Walker, O	1
Chisale, M; Kazembe, P; Molyneux, ME; Ratsma, EY; Taylor, TE; Wills, BA; Wirima, JJ	1
Molyneux, M; Taylor, T; Wills, B; Wirima, J	1
Courtright, P; Lewallen, S; Molyneux, ME; Taylor, TE; Wills, BA	1
Bennett, S; Enwere, G; Forck, S; Frenkel, J; Greenwood, B; Jaffar, S; Kwiatkowski, D; Nusmeijer, A; Onyiorah, E; Palmer, A; Schneider, G; van Hensbroek, MB	1
Bienzle, U; Kremsner, PG; Müller, S; Prada, J	1
Fruchter, O	1
Garg, RK	1
Jaffar, S; Kwiatkowski, D; Palmer, A; Schneider, G; van Hensbroek, MB	1
Courval, JM; Molyneux, ME; Taylor, TE; Wills, BA	1
Newton, CR; Warrell, DA	1
Gravenor, MB; Kwiatkowski, D; van Hensbroek, MB	1
Adeyemo, AA; Björkman, A; Gbadegesin, RA; Olumese, PE; Walker, O	1
Chau, TT; Chu'ong, LV; Day, NP; Farrar, J; Hien, TT; Hunt, NH; Mai, NT; Medana, IM; Phu, NH; Salahifar, H; Smythe, G; Stocker, R; Taylor, A; Turner, GD; White, NJ	1
Lalloo, D; Trevett, A	1
Hla, KK; Shwe, T	1
Than, M; Thwe, Y; Win, K	1

Reviews

6 review(s) available for artemether and Cerebral Malaria

Article	Year
Comparative efficacy and safety of the artemisinin derivatives compared to quinine for treating severe malaria in children and adults: A systematic update of literature and network meta-analysis. PloS one, 2022, Volume: 17, Issue:7 Topics: Adult; Antimalarials; Artemether; Artemisinins; Artesunate; Child; Humans; Malaria, Cerebral; Malaria, Falciparum; Network Meta-Analysis; Quinine	2022
Artemether for severe malaria. The Cochrane database of systematic reviews, 2019, 06-18, Volume: 6 Topics: Adolescent; Adult; Africa; Age Factors; Antimalarials; Artemether; Artesunate; Asia; Child; Child, Preschool; Coma; Fever; Humans; Infant; Injections, Intramuscular; Malaria, Cerebral; Malaria, Falciparum; Oceania; Quinine; Randomized Controlled Trials as Topic; Treatment Outcome	2019
Artemether for severe malaria. The Cochrane database of systematic reviews, 2014, Sep-11, Issue:9 Topics: Adolescent; Adult; Africa; Antimalarials; Artemether; Artemisinins; Artesunate; Asia; Child; Child, Preschool; Humans; Infant; Injections, Intramuscular; Malaria, Cerebral; Malaria, Falciparum; Oceania; Quinine; Randomized Controlled Trials as Topic	2014
Artemisinin-based combination therapies and their introduction in Japan. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2010, Volume: 16, Issue:6 Topics: Animals; Antimalarials; Artemether; Artemisia annua; Artemisinins; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Japan; Lumefantrine; Malaria, Cerebral; Malaria, Falciparum; Mefloquine; Plasmodium falciparum	2010
Neurological manifestations of falciparum malaria. Annals of neurology, 1998, Volume: 43, Issue:6 Topics: Adult; Antimalarials; Artemether; Artemisinins; Artesunate; Child; Humans; Malaria, Cerebral; Quinidine; Quinine; Sesquiterpenes	1998
A new look at an old drug: artemesinin and qinghaosu. Papua and New Guinea medical journal, 1992, Volume: 35, Issue:4 Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Humans; Malaria, Cerebral; Malaria, Falciparum; Sesquiterpenes	1992

Trials

13 trial(s) available for artemether and Cerebral Malaria

Article	Year
The efficacy of artemether versus quinine in the treatment of cerebral malaria. Journal of the Egyptian Society of Parasitology, 2002, Volume: 32, Issue:2 Topics: Adolescent; Animals; Antimalarials; Artemether; Artemisinins; Child; Child, Preschool; Drug Resistance; Female; Humans; Infant; Malaria, Cerebral; Male; Quinine; Sesquiterpenes; Time Factors; Treatment Outcome	2002
Comparison of intramuscular artemether and intravenous quinine in the treatment of Sudanese children with severe falciparum malaria. East African medical journal, 2002, Volume: 79, Issue:12 Topics: Animals; Antimalarials; Artemether; Artemisinins; Child; Child, Preschool; Coma; Female; Fever; Humans; Infusions, Intravenous; Injections, Intramuscular; Malaria, Cerebral; Malaria, Falciparum; Male; Plasmodium falciparum; Quinine; Sesquiterpenes; Sudan; Treatment Outcome	2002
Rectal artemether versus intravenous quinine for the treatment of cerebral malaria in children in Uganda: randomised clinical trial. BMJ (Clinical research ed.), 2005, Feb-12, Volume: 330, Issue:7487 Topics: Administration, Rectal; Antimalarials; Artemether; Artemisinins; Child; Child, Preschool; Humans; Infant; Infusions, Intravenous; Malaria, Cerebral; Parasitemia; Quinine; Sesquiterpenes; Single-Blind Method; Suppositories; Time Factors; Treatment Outcome; Uganda	2005
Artemether in moderately severe and cerebral malaria in Nigerian children. Transactions of the Royal Society of Tropical Medicine and Hygiene, 1994, Volume: 88 Suppl 1 Topics: Antimalarials; Antiprotozoal Agents; Artemether; Artemisinins; Child; Child, Preschool; Drug Combinations; Humans; Infant; Malaria, Cerebral; Malaria, Falciparum; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Outcome	1994
Rapid coma resolution with artemether in Malawian children with cerebral malaria. Lancet (London, England), 1993, Mar-13, Volume: 341, Issue:8846 Topics: Animals; Antimalarials; Artemether; Artemisinins; Child, Preschool; Coma; Female; Humans; Infant; Malaria, Cerebral; Malawi; Male; Plasmodium falciparum; Proportional Hazards Models; Quinine; Sesquiterpenes; Time Factors; Treatment Outcome	1993
Ocular fundus findings in Malawian children with cerebral malaria. Ophthalmology, 1993, Volume: 100, Issue:6 Topics: Antimalarials; Artemether; Artemisinins; Blood Glucose; Child; Child, Preschool; Fundus Oculi; Humans; Infant; Malaria, Cerebral; Malawi; Ophthalmoscopy; Papilledema; Prognosis; Quinine; Sesquiterpenes; World Health Organization	1993
A trial of artemether or quinine in children with cerebral malaria. The New England journal of medicine, 1996, Jul-11, Volume: 335, Issue:2 Topics: Antimalarials; Artemether; Artemisinins; Central Nervous System Diseases; Child; Child, Preschool; Female; Humans; Injections, Intramuscular; Malaria, Cerebral; Male; Odds Ratio; Quinine; Sesquiterpenes; Survival Analysis; Treatment Outcome	1996
Chemotherapy for cerebral malaria. Indian pediatrics, 1996, Volume: 33, Issue:12 Topics: Antimalarials; Artemether; Artemisinins; Child; Child, Preschool; Humans; Infant; Injections, Intramuscular; Malaria, Cerebral; Malaria, Falciparum; Quinine; Sesquiterpenes; Treatment Outcome	1996
Intramuscular artemether vs intravenous quinine: an open, randomized trial in Malawian children with cerebral malaria. Tropical medicine & international health : TM & IH, 1998, Volume: 3, Issue:1 Topics: Antimalarials; Artemether; Artemisinins; Child, Preschool; Coma; Electrocardiography; Female; Fever; Humans; Infant; Infusions, Intravenous; Injections, Intramuscular; Malaria, Cerebral; Male; Nervous System Diseases; Parasitemia; Prognosis; Quinine; Recurrence; Sesquiterpenes; Survival Analysis; Time Factors	1998
Comparative efficacy of intramuscular artemether and intravenous quinine in Nigerian children with cerebral malaria. Acta tropica, 1999, Oct-15, Volume: 73, Issue:3 Topics: Antimalarials; Artemether; Artemisinins; Child, Preschool; Humans; Infant; Malaria, Cerebral; Nigeria; Quinine; Sesquiterpenes; Treatment Outcome	1999
The clinical significance of cerebrospinal fluid levels of kynurenine pathway metabolites and lactate in severe malaria. The Journal of infectious diseases, 2002, Mar-01, Volume: 185, Issue:5 Topics: Adolescent; Adult; Aged; Animals; Antimalarials; Artemether; Artemisinins; Humans; Kynurenine; Lactates; Malaria, Cerebral; Middle Aged; Picolinic Acids; Plasmodium falciparum; Quinine; Quinolinic Acid; Sesquiterpenes	2002
The effect of artemether plus mefloquine on Myanmar patients with complicated falciparum malaria. The Southeast Asian journal of tropical medicine and public health, 1992, Volume: 23 Suppl 4 Topics: Antimalarials; Artemether; Artemisinins; Drug Therapy, Combination; Humans; Malaria, Cerebral; Malaria, Falciparum; Mefloquine; Myanmar; Quinine; Recurrence; Sesquiterpenes; Survival Rate	1992
Comparison of combinations of parenteral artemisinin derivatives plus oral mefloquine with intravenous quinine plus oral tetracycline for treating cerebral malaria. Bulletin of the World Health Organization, 1992, Volume: 70, Issue:6 Topics: Adolescent; Adult; Antimalarials; Artemether; Artemisinins; Artesunate; Humans; Malaria, Cerebral; Mefloquine; Middle Aged; Prospective Studies; Quinine; Sesquiterpenes; Tetracycline	1992

Other Studies

22 other study(ies) available for artemether and Cerebral Malaria

Article	Year
NO-Donor Dihydroartemisinin Derivatives as Multitarget Agents for the Treatment of Cerebral Malaria. Journal of medicinal chemistry, 2015, Oct-08, Volume: 58, Issue:19 Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Chemistry Techniques, Synthetic; Malaria, Cerebral; Mice; Molecular Targeted Therapy; Muscle Relaxation; Nitric Oxide Donors; Plasmodium berghei; Rats; Vasodilator Agents	2015
Intravenous whole blood transfusion results in faster recovery of vascular integrity and increased survival in experimental cerebral malaria. Memorias do Instituto Oswaldo Cruz, 2023, Volume: 117 Topics: Administration, Intravenous; Animals; Antimalarials; Artemether; Artemisinins; Blood Component Transfusion; Malaria, Cerebral; Malaria, Falciparum; Mice; Plasma	2023
Whole blood transfusion improves vascular integrity and increases survival in artemether-treated experimental cerebral malaria. Scientific reports, 2021, 06-08, Volume: 11, Issue:1 Topics: Animals; Artemether; Blood Transfusion; Female; Malaria, Cerebral; Mice; Plasmodium berghei	2021
Ameliorating the in vivo antimalarial efficacy of artemether using nanostructured lipid carriers. Journal of microencapsulation, 2018, Volume: 35, Issue:2 Topics: Animals; Antimalarials; Artemether; Artemisinins; Brain; Diglycerides; Drug Carriers; Drug Delivery Systems; HEK293 Cells; Humans; Lipids; Malaria, Cerebral; Male; Mice, Inbred C57BL; Monoglycerides; Nanostructures; Particle Size; Plasmodium berghei; Surface-Active Agents	2018
Pharmacologic inhibition of CXCL10 in combination with anti-malarial therapy eliminates mortality associated with murine model of cerebral malaria. PloS one, 2013, Volume: 8, Issue:4 Topics: Animals; Antimalarials; Apoptosis; Artemether; Artemisinins; Atorvastatin; Blood-Brain Barrier; Caspases; Cell Count; Chemokine CXCL10; Disease Models, Animal; Drug Interactions; Endothelial Cells; Gene Expression Regulation; Heme Oxygenase-1; Heptanoic Acids; Humans; Leukocytes; Malaria, Cerebral; Membrane Proteins; Mice; Mice, Inbred C57BL; Models, Molecular; Neuroglia; Nucleic Acid Conformation; Pyrroles; Survival Analysis	2013
Transdermal glyceryl trinitrate as an effective adjunctive treatment with artemether for late-stage experimental cerebral malaria. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:11 Topics: Administration, Cutaneous; Animals; Antimalarials; Artemether; Artemisinins; Arterial Pressure; Brain; Drug Synergism; Female; Gene Expression; Malaria, Cerebral; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type I; Nitroglycerin; Plasmodium berghei; Survival Analysis; Treatment Outcome; Vasoconstriction; Vasodilator Agents	2013
Neuregulin-1 attenuates mortality associated with experimental cerebral malaria. Journal of neuroinflammation, 2014, Jan-17, Volume: 11 Topics: Animals; Antimalarials; Artemether; Artemisinins; Behavior, Animal; Blood-Brain Barrier; Brain; Cytokines; Disease Models, Animal; Encephalitis; Endothelium; Leukocytes; Malaria, Cerebral; Mice; Mice, Inbred C57BL; Neuregulin-1; Neuroprotective Agents; Plasmodium berghei	2014
From METS to malaria: RRx-001, a multi-faceted anticancer agent with activity in cerebral malaria. Malaria journal, 2015, May-28, Volume: 14 Topics: Animals; Antimalarials; Artemether; Artemisinins; Azetidines; Carboxylic Ester Hydrolases; Disease Models, Animal; Drug Combinations; Glucosephosphate Dehydrogenase; Humans; Malaria, Cerebral; Mice; Mice, Inbred C57BL; Motor Activity; Nitro Compounds; Parasitemia; Plasmodium berghei	2015
Cerebral malaria: a vasculopathy. The American journal of pathology, 2010, Volume: 176, Issue:3 Topics: Animals; Artemether; Artemisinins; Humans; Malaria, Cerebral; Mice; Nimodipine; Plasmodium berghei; Vasospasm, Intracranial	2010
Murine cerebral malaria is associated with a vasospasm-like microcirculatory dysfunction, and survival upon rescue treatment is markedly increased by nimodipine. The American journal of pathology, 2010, Volume: 176, Issue:3 Topics: Animals; Artemether; Artemisinins; Arterioles; Body Temperature; Cell Adhesion; Cerebrovascular Circulation; Erythrocytes; Leukocytes; Malaria, Cerebral; Mice; Mice, Inbred C57BL; Microcirculation; Nimodipine; Parasitemia; Plasmodium berghei; Survival Analysis; Vasoconstriction; Vasodilation; Vasospasm, Intracranial	2010
Artemether and artesunate show the highest efficacies in rescuing mice with late-stage cerebral malaria and rapidly decrease leukocyte accumulation in the brain. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:4 Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Brain; Leukocytes; Malaria, Cerebral; Mefloquine; Mice; Parasitemia; Plasmodium berghei; Quinine	2011
The novel ETA receptor antagonist HJP-272 prevents cerebral microvascular hemorrhage in cerebral malaria and synergistically improves survival in combination with an artemisinin derivative. Life sciences, 2012, Oct-15, Volume: 91, Issue:13-14 Topics: Animals; Antimalarials; Artemether; Artemisinins; Cerebral Hemorrhage; Drug Synergism; Drug Therapy, Combination; Endothelin A Receptor Antagonists; Endothelin-1; Female; Hydroxyquinolines; Malaria, Cerebral; Mice; Mice, Inbred C57BL; Microvessels; Parasitemia; Plasmodium berghei; Random Allocation; Survival	2012
[Severe malaria: assessment of the treatment of anaemia and cerebral manifestations in a tropical intensive cares unit]. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2006, Volume: 13, Issue:12 Topics: Age Factors; Anemia; Antimalarials; Artemether; Artemisinins; Blood Transfusion; Child; Child, Preschool; Cross-Over Studies; Humans; Infant; Injections, Intramuscular; Intensive Care Units, Pediatric; Malaria, Cerebral; Malaria, Falciparum; Prognosis; Quality of Health Care; Quinine; Togo	2006
[Blackwater fever in children during cerebral malaria: 3 case reports in Bamako]. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2007, Volume: 14, Issue:8 Topics: Acute Kidney Injury; Antimalarials; Artemether; Artemisinins; Blackwater Fever; Child; Child, Preschool; Female; Humans; Malaria, Cerebral; Male; Mali; Oliguria	2007
Cerebral malaria in children in South Sudan: 8 years experience in 261 cases. Neuro endocrinology letters, 2007, Volume: 28 Suppl 2 Topics: Antimalarials; Artemether; Artemisinins; Child, Preschool; Clindamycin; Coma; Comorbidity; Drug Therapy, Combination; Fever; Humans; Infant; Malaria, Cerebral; Quinine; Retrospective Studies; Seizures; Sudan	2007
Ten years experience with 497 cases of neuroinfections in tropic: in limited laboratory infrastructure initially treat both, cerebral malaria and meningitis. Neuro endocrinology letters, 2007, Volume: 28 Suppl 2 Topics: Africa South of the Sahara; Anti-Bacterial Agents; Antimalarials; Artemether; Artemisinins; Ceftriaxone; Chloramphenicol; Diagnosis, Differential; Drug Therapy, Combination; Humans; Laboratories; Malaria, Cerebral; Medically Underserved Area; Meningitis, Bacterial; Quinine; Retrospective Studies; Tropical Medicine	2007
[Complicated malaria tropica--therapy with artemether]. Wiener medizinische Wochenschrift (1946), 1994, Volume: 144, Issue:4 Topics: Adult; Antimalarials; Artemether; Artemisinins; Cambodia; Critical Care; Drug Therapy, Combination; Female; Humans; Injections, Intramuscular; Malaria; Malaria, Cerebral; Male; Pregnancy; Pregnancy Complications, Parasitic; Sesquiterpenes	1994
Artemether in cerebral malaria. Lancet (London, England), 1993, Jun-19, Volume: 341, Issue:8860 Topics: Antimalarials; Artemether; Artemisinins; Child; Humans; Malaria, Cerebral; Sesquiterpenes; Treatment Outcome	1993
Upregulation of reactive oxygen and nitrogen intermediates in Plasmodium berghei infected mice after rescue therapy with chloroquine or artemether. The Journal of antimicrobial chemotherapy, 1996, Volume: 38, Issue:1 Topics: Animals; Antimalarials; Artemether; Artemisinins; Chloroquine; Enzyme Induction; Female; Genetic Code; In Situ Hybridization; Malaria, Cerebral; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase; Nitrogen Compounds; Plasmodium berghei; Reactive Oxygen Species; Sesquiterpenes; Spleen; Up-Regulation	1996
Artemether in severe malaria. The New England journal of medicine, 1996, Dec-19, Volume: 335, Issue:25 Topics: Antimalarials; Artemether; Artemisinins; Chelation Therapy; Child; Coma; Deferoxamine; Humans; Malaria, Cerebral; Quinine; Sesquiterpenes	1996
Residual neurologic sequelae after childhood cerebral malaria. The Journal of pediatrics, 1997, Volume: 131, Issue:1 Pt 1 Topics: Acidosis, Lactic; Antimalarials; Artemether; Artemisinins; Ataxia; Brain Diseases; Cause of Death; Child; Child, Preschool; Coma; Female; Forecasting; Gambia; Humans; Hypoglycemia; Infant; Logistic Models; Longitudinal Studies; Malaria, Cerebral; Male; Paresis; Patient Admission; Patient Discharge; Prospective Studies; Quinine; Risk Factors; Seizures; Sesquiterpenes; Survival Rate; Time Factors; Treatment Outcome; Tropical Climate; Unconsciousness	1997
Estimating sequestered parasite population dynamics in cerebral malaria. Proceedings of the National Academy of Sciences of the United States of America, 1998, Jun-23, Volume: 95, Issue:13 Topics: Animals; Antimalarials; Artemether; Artemisinins; Child; Erythrocytes; Host-Parasite Interactions; Humans; Malaria, Cerebral; Parasitemia; Plasmodium falciparum; Quinine; Sesquiterpenes	1998