Compounds > arsenic trioxide
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arsenic trioxide and Medulloblastoma

arsenic trioxide has been researched along with Medulloblastoma in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (77.78)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Andrade, AF; Cruzeiro, GAV; das Chagas, PF; de Andrade, PV; de Oliveira, RS; de Paula Queiroz, RG; Delsin, LEA; Dos Santos Klinger, PH; Lira, RCP; Scrideli, CA; Tone, LG; Trevisan, FA; Valera, ET1
Andrade, AF; Delsin, LE; Klinger, PH; Queiroz, RG; Scrideli, CA; Tone, LG; Valera, ET1
Beachy, PA; Gardner, D; Kim, J; Lee, JJ1
Raju, GP1
Albanese, C; Beauchamp, EM; Bulut, G; Hall, MD; Lee, YC; Macdonald, TJ; Ozdemirli, M; Peaceman, D; Ringer, L; Rodriguez, O; Sajwan, KP; Toretsky, JA; Uren, A1
Amano, S; Gao, Y; Gu, C; Koizumi, S; Namba, H; Tokuyama, T; Yokota, N1
Beauchamp, EM; Uren, A1
Aftab, BT; Beachy, PA; Borodovsky, A; Chen, B; Epstein, EH; Kim, D; Kim, J; King, EM; Lee, AH; Rezaee, M; Riggins, GJ; Rudin, CM; Tang, JY1
Hadden, MK; Wen, J1

Reviews

3 review(s) available for arsenic trioxide and Medulloblastoma

ArticleYear
Inhibition of SHH pathway mechanisms by arsenic trioxide in pediatric medulloblastomas: a comprehensive literature review.
    Genetics and molecular research : GMR, 2017, Feb-16, Volume: 16, Issue:1

    Topics: Adolescent; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Cerebellar Neoplasms; Child; Child, Preschool; Gene Expression Regulation, Neoplastic; Hedgehog Proteins; Humans; Infant; Medulloblastoma; Oxides; Signal Transduction

2017
A new era for an ancient drug: arsenic trioxide and Hedgehog signaling.
    Vitamins and hormones, 2012, Volume: 88

    Topics: Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Bone Neoplasms; Cerebellar Neoplasms; Hedgehog Proteins; Humans; Leukemia, Promyelocytic, Acute; Medulloblastoma; Oncogene Proteins; Oxides; Sarcoma, Ewing

2012
Medulloblastoma drugs in development: Current leads, trials and drawbacks.
    European journal of medicinal chemistry, 2021, Apr-05, Volume: 215

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cerebellar Neoplasms; Humans; Medulloblastoma; Protein Kinase Inhibitors

2021

Other Studies

6 other study(ies) available for arsenic trioxide and Medulloblastoma

ArticleYear
Arsenic Trioxide exerts cytotoxic and radiosensitizing effects in pediatric Medulloblastoma cell lines of SHH Subgroup.
    Scientific reports, 2020, 04-22, Volume: 10, Issue:1

    Topics: Apoptosis; Arsenic Trioxide; Cell Line, Tumor; Child; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Medulloblastoma; Neoplasm Proteins; Radiation-Sensitizing Agents

2020
Arsenic antagonizes the Hedgehog pathway by preventing ciliary accumulation and reducing stability of the Gli2 transcriptional effector.
    Proceedings of the National Academy of Sciences of the United States of America, 2010, Jul-27, Volume: 107, Issue:30

    Topics: Animals; Arsenic Trioxide; Arsenicals; Arsenites; Cerebellar Neoplasms; Dose-Response Relationship, Drug; Hedgehog Proteins; Kruppel-Like Transcription Factors; Luciferases; Luminescent Proteins; Medulloblastoma; Mice; Mice, Knockout; Mice, Nude; Neoplasms, Experimental; NIH 3T3 Cells; Oxides; Protein Stability; Recombinant Fusion Proteins; Signal Transduction; Sodium Compounds; Transfection; Transplantation, Homologous; Tumor Suppressor Protein p53; Zinc Finger Protein Gli2

2010
Arsenic: a potentially useful poison for Hedgehog-driven cancers.
    The Journal of clinical investigation, 2011, Volume: 121, Issue:1

    Topics: Animals; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Hedgehog Proteins; Humans; Medulloblastoma; Mice; Models, Biological; Neoplasms; Oxides; Receptors, G-Protein-Coupled; Sarcoma, Ewing; Signal Transduction; Smoothened Receptor; Transcription Factors; Zinc Finger Protein GLI1

2011
Arsenic trioxide inhibits human cancer cell growth and tumor development in mice by blocking Hedgehog/GLI pathway.
    The Journal of clinical investigation, 2011, Volume: 121, Issue:1

    Topics: Animals; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Base Sequence; Cell Line, Tumor; DNA Primers; Gene Expression; Hedgehog Proteins; Hep G2 Cells; Humans; Medulloblastoma; Mice; Mice, SCID; Mice, Transgenic; Neoplasm Transplantation; Oncogene Proteins; Oxides; Receptors, G-Protein-Coupled; Recombinant Fusion Proteins; Sarcoma, Ewing; Signal Transduction; Smoothened Receptor; Trans-Activators; Transplantation, Heterologous; Zinc Finger Protein GLI1

2011
Molecular targeting therapy against promyelocytic leukemia protein using arsenic acids in experimental intracranial medulloblastoma.
    Neurologia medico-chirurgica, 2012, Volume: 52, Issue:2

    Topics: Animals; Antineoplastic Agents; Arsenates; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Cerebellar Neoplasms; Cytarabine; Humans; Medulloblastoma; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Targeted Therapy; Neoplasms, Experimental; Nuclear Proteins; Oxides; Promyelocytic Leukemia Protein; Transcription Factors; Tumor Suppressor Proteins

2012
Itraconazole and arsenic trioxide inhibit Hedgehog pathway activation and tumor growth associated with acquired resistance to smoothened antagonists.
    Cancer cell, 2013, Jan-14, Volume: 23, Issue:1

    Topics: Anilides; Animals; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Carcinoma, Basal Cell; Drug Resistance, Neoplasm; Hedgehog Proteins; Itraconazole; Medulloblastoma; Mice; Oxides; Pyridines; Receptors, G-Protein-Coupled; Signal Transduction; Smoothened Receptor

2013