Compounds > arsenic trioxide
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arsenic trioxide and Malignant Melanoma

arsenic trioxide has been researched along with Malignant Melanoma in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (66.67)29.6817
2010's3 (25.00)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Emri, G; Fidrus, E; Hegedűs, C; Janka, EA; Paragh, G; Remenyik, É1
Balaz, P; Bujnakova, Z; Cholujova, D; Duraj, J; Gronesova, P; Hunakova, L; Lee, TC; Pastorek, M; Sedlak, J1
Corti, A; Favini, E; Giommarelli, C; Paolicchi, A; Pompella, A; Supino, R; Zunino, F1
Chen, MF; Chen, MJ; Hu, DN; Yang, PY; Ye, YZ1
Castellani, P; Ciriolo, MR; Delfino, L; Lucibello, M; Rubartelli, A; Venè, R1
Doñate, F; Fruehauf, JP; Lee, K; Mazar, AP; Trapp, V1
Bedikian, AY; Camacho, LH; Kim, KB; McCullough, C; Papadopoulos, NE1
Li, B; Li, WH; Sun, YL; Wang, CF; Xu, YL; Zhang, HY1
Jonas, JB; Li, B; Li, W; Shi, G; Wang, C; Zhang, H1
Agarwala, SS; Gooding, WE; Islam, MF; Kirkwood, JM; Tarhini, AA; Tawbi, H1
Bowling, BD; Doudican, N; Manga, P; Orlow, SJ1
Bael, TE; Gollob, JA; Peterson, BL1

Trials

3 trial(s) available for arsenic trioxide and Malignant Melanoma

ArticleYear
A phase II trial of arsenic trioxide in patients with metastatic melanoma.
    Cancer, 2005, Oct-15, Volume: 104, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Choroid Neoplasms; Female; Humans; Lymphatic Metastasis; Male; Melanoma; Middle Aged; Oxides; Skin Neoplasms; Survival Rate; Treatment Outcome

2005
Safety and efficacy of arsenic trioxide for patients with advanced metastatic melanoma.
    Cancer, 2008, Mar-01, Volume: 112, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Choroid Neoplasms; Drug Administration Schedule; Female; Humans; Male; Melanoma; Middle Aged; Oxides; Skin Neoplasms

2008
Phase II trial of arsenic trioxide and ascorbic acid with temozolomide in patients with metastatic melanoma with or without central nervous system metastases.
    Melanoma research, 2008, Volume: 18, Issue:2

    Topics: Adult; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Brain Neoplasms; Dacarbazine; Female; Humans; Male; Melanoma; Middle Aged; Oxides; Skin Neoplasms; Temozolomide

2008

Other Studies

9 other study(ies) available for arsenic trioxide and Malignant Melanoma

ArticleYear
Inhibitors of Nucleotide Excision Repair Decrease UVB-Induced Mutagenesis-An In Vitro Study.
    International journal of molecular sciences, 2021, Feb-06, Volume: 22, Issue:4

    Topics: Animals; Arsenic Trioxide; Autophagy; Benzimidazoles; Cell Cycle Checkpoints; Cell Line, Transformed; Cell Survival; CHO Cells; Cricetulus; DNA Damage; DNA Repair; HaCaT Cells; Humans; Hypoxanthine Phosphoribosyltransferase; Melanoma; Mutation Rate; Pyrimidine Dimers; Resveratrol; Skin; Skin Neoplasms; Spironolactone; Ultraviolet Rays

2021
Realgar (As4S4) nanoparticles and arsenic trioxide (As2O3) induced autophagy and apoptosis in human melanoma cells in vitro.
    Neoplasma, 2014, Volume: 61, Issue:6

    Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Autophagy; Cell Line, Tumor; Cell Proliferation; Chloroquine; DNA Damage; Glutathione; Humans; Melanoma; Nanoparticles; Oxides; Phosphorylation; Sulfides

2014
Gamma-glutamyltransferase-dependent resistance to arsenic trioxide in melanoma cells and cellular sensitization by ascorbic acid.
    Free radical biology & medicine, 2009, Jun-01, Volume: 46, Issue:11

    Topics: Apoptosis; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Catalase; Cell Line, Tumor; Cytoprotection; Drug Resistance, Neoplasm; Enzyme Activation; gamma-Glutamyltransferase; Gene Expression Regulation, Neoplastic; Growth Inhibitors; Humans; MAP Kinase Kinase Kinase 5; Melanoma; Oxidative Stress; Oxides

2009
Arsenic trioxide induces apoptosis in uveal melanoma cells through the mitochondrial pathway.
    The American journal of Chinese medicine, 2010, Volume: 38, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Cell Line, Tumor; Cytochromes c; DNA Fragmentation; Dose-Response Relationship, Drug; Eye Neoplasms; Humans; Melanoma; Mitochondria; Oxides; Phytotherapy; Proto-Oncogene Proteins c-bcl-2; Signal Transduction

2010
The cystine/cysteine cycle and GSH are independent and crucial antioxidant systems in malignant melanoma cells and represent druggable targets.
    Antioxidants & redox signaling, 2011, Nov-01, Volume: 15, Issue:9

    Topics: Antioxidants; Arsenic Trioxide; Arsenicals; Blotting, Western; Buthionine Sulfoximine; Cell Survival; Cysteine; Cystine; Glutathione; Glycine; HMGB1 Protein; Humans; Immunohistochemistry; Melanoma; Oxidation-Reduction; Oxides; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Tumor Cells, Cultured

2011
Redox-related antimelanoma activity of ATN-224.
    Melanoma research, 2009, Volume: 19, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Buthionine Sulfoximine; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Disulfiram; Drug Synergism; Enzyme Inhibitors; Glutathione; Humans; Melanins; Melanoma; Molybdenum; Oxidation-Reduction; Oxides; Reactive Oxygen Species; Superoxide Dismutase; Temozolomide

2009
[In vitro study on inhibition of human choroidal melanoma OCM-1 cell line by arsenic trioxide].
    [Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 2005, Volume: 41, Issue:10

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Choroid Neoplasms; Dose-Response Relationship, Drug; Glutathione Peroxidase; Humans; Melanoma; Oxides

2005
Effect of arsenic trioxide on uveal melanoma cell proliferation in vitro.
    Ophthalmic research, 2007, Volume: 39, Issue:6

    Topics: Apoptosis; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Flow Cytometry; Glutathione Peroxidase; Growth Inhibitors; Humans; Melanoma; Membrane Potentials; Microscopy, Electron; Mitochondria; Necrosis; Osmolar Concentration; Oxides

2007
Inhibition of mitochondrial protein translation sensitizes melanoma cells to arsenic trioxide cytotoxicity via a reactive oxygen species dependent mechanism.
    Cancer chemotherapy and pharmacology, 2008, Volume: 63, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; Drug Synergism; Electron Transport Complex IV; Humans; Inhibitory Concentration 50; Melanoma; Mitochondrial Proteins; Oxides; Poly Adenosine Diphosphate Ribose; Protein Biosynthesis; Protein Synthesis Inhibitors; Reactive Oxygen Species; Tetracyclines; Thiostrepton

2008