Page last updated: 2024-08-21

arsenic trioxide and Lung Neoplasms

arsenic trioxide has been researched along with Lung Neoplasms in 80 studies

Research

Studies (80)

Timeframe	Studies, this research(%)	All Research%
pre-1990	6 (7.50)	18.7374
1990's	1 (1.25)	18.2507
2000's	25 (31.25)	29.6817
2010's	40 (50.00)	24.3611
2020's	8 (10.00)	2.80

Authors

Authors	Studies
Chang, KJ; Li, B; Yang, MH	1
Li, X; Shen, Y; Zhang, R	1
Chen, WJ; Chen, ZH; Han, L; Lei, GY; Yuan, B; Zhang, YL	1
Du, H; Li, B; Shi, XQ; Wang, MD; Yang, MH; Yin, JZ; Zhao, XW	1
Li, B; Shi, XQ; Wang, YS; Yang, MH; Yin, JZ; Zhao, XW	1
Han, BR; Park, HK; Park, WH	1
Chang, WC; Chao, KSC; Cheng, WC; Cho, CF; Hsiao, TH; Hsu, JL; Huang, YK; Hung, MC; Kuo, TT; Lai, LC; Lee, PC; Lin, CC; Lin, YS; Liu, YH; Lo, CC; Sher, YP; Shih, JY; Sun, X; Tseng, GC	1
An, H; Bae, I; Heo, JS; Hong, E; Kim, P; Kim, SJ; Lee, J; Lee, S; Lian, Z; Ooshima, A; Pang, K; Park, H; Park, J; Park, KS; Park, Y; Son, M; Wu, Z; Yang, KM	1
Cai, NL; Dai, LJ; Jin, DY; Lau, ATY; Ok Kim, M; Wu, DD; Xu, YM; Yu, FY	1
Chen, H; Gu, S; Lai, Y; Liu, Y; Zhang, Z	1
Chen, HY; Dai, HM; Gu, SY; Li, XY; Zhang, ZZ	1
Huang, W; Zeng, YC	1
Chang, KJ; Chen, WS; Li, B; Yang, MH	1
He, LJ; Jia, YL; Nan, X; Pei, XT; Wang, DX; Wang, HY; Xi, JF; Xu, YC; Yue, W; Zeng, Q; Zhang, B; Zhou, JN	1
Fong, BM; Ho, JC; Lam, SK; Li, YY; Mak, JC; Zheng, CY	1
Chen, C; Jiang, X; Ren, Y; Zhang, Z	1
Nguyen, DM; Robbins, DJ; Savaraj, N; Singh, S; Varona-Santos, J; You, M	1
Amirheidari, B; Ghahremani, MH; Mandegary, A; Seyedabadi, M; Sharif, E; Torshabi, M	1
Arrighetti, N; Carenini, N; Cominetti, D; Cossa, G; De Cesare, M; Gatti, L; Pennati, M; Perego, P; Tinelli, S; Zaffaroni, N; Zunino, F	1
Ho, JC; Kwong, YL; Lam, SK; Li, YY; Mak, JC; Zheng, CY	1
Fang, ZT; Li, S; Liu, R; Qian, S; Qu, XD; Wang, GZ; Wang, JH; Wang, LL; Yang, GW; Yang, MJ; Zhang, W; Zhang, WS; Zhu, L	1
Chen, X; Jiang, H; Li, Y; Liang, Y; Liu, J; Liu, L; Lu, Z; Meng, X; Pan, S; Qi, S; Song, X; Sun, B; Wang, J; Xie, C; Yin, D; Zheng, T	1
Chang, YW; Chen, CA; Chen, MW; Cheng, CC; Chiu, CF; Hong, CC; Hsiao, M; Su, JL; Wei, LH	1
Abematsu, M; Fujimoto, Y; Ishidou, Y; Kitajima, S; Kitamoto, S; Komiya, S; Maeda, S; Nagano, S; Nagao-Kitamoto, H; Nagata, M; Nakamura, S; Setoguchi, T; Tsuru, A; Yamamoto, T; Yokouchi, M; Yonezawa, S; Yoshioka, T	1
Chen, K; Huang, H; Li, B; Sun, GY; Yang, MH; Zang, YS; Zhao, XW	1
Ho, JC; Lam, SK; Leung, LL; Li, YY; Zheng, CY	2
Ho, JC; Lam, SK; Li, YY; Zheng, CY	2
Chen, K; Huang, H; Li, B; Xie, SL; Yang, MH; Zang, YS; Zhao, XW	1
Chen, C; Gu, S; Jiang, X; Zhang, Z	3
He, X; Hu, BS; Huang, JW; Li, Y; Liu, B; Lu, LG; Zhao, W; Zheng, YB	1
Chen, C; Hu, H; Li, H	1
Bechara, R; Chen, Z; Deng, X; Khuri, FR; Kim, HS; Owonikoko, TK; Pakkala, S; Pillai, R; Ramalingam, SS; Rossi, MR; Saba, NF; Sica, GL; Stinson, RM; Sun, SY; Zhang, C; Zhang, G	1
Chen, H; Dai, H; Gu, S; Li, X; Zhang, Z	1
Han, YH; Kim, SH; Kim, SZ; Park, WH	2
Nelson, R; Self, WT; Talbot, S	1
Jang, HY; Jeong, ET; Jo, HJ; Kim, EJ; Kim, HJ; Kim, HR; Lee, KK; Park, JH; Shim, H; Yang, SH	1
Borghi, M; Castellani, P; Ceccarelli, J; Delfino, L; Ferrini, S; Rubartelli, A; Tosetti, F; Zappia, E	1
Aklilu, M; Kindler, HL; Nattam, S; Vokes, EE	1
Chang, EE; Miao, ZF; Tsai, FY; Tsou, TC; Wang, CJ; Wu, CF; Wu, KY; Yeh, SC	1
Johansson, L; Karlsson, J; Munksgaard Persson, M; Påhlman, S; Pettersson, HM; Pietras, A; Shoshan, MC	1
Sorahan, T	1
Chen, H; Li, H; Xiang, J; Zhang, Y; Zhu, X	1
Jiang, HC; Liu, TF; Song, PL; Sun, B; Zhao, XS	1
Li, B; Liu, YA; Qu, GP; Xiu, QY; Zhang, LZ	1
Han, YH; Kim, SH; Kim, SZ; Moon, HJ; Park, WH; You, BR	2
Ndebele, K; Stevens, JJ; Tchounwou, PB; Walker, AM	1
Chang, SY; Chien, CW; Lee, PC; Lee, TC; Yao, JH	1
Shi, Y; Xia, J; Yang, TH	1
Chen, Q; Hao, XZ; Liu, JW; Qin, SK; Qu, FL; Qu, T; Sui, GJ; Sun, Y; Zhang, HP	1
Byers, LA; Carter, B; Chiang, CM; Girard, L; Heymach, JV; Konstantinidou, G; Rabellino, A; Rimessi, A; Scaglioni, PP; Teruya-Feldstein, J; Wu, SY	1
Barnett, JB; Davis, ME; Holaskova, I; Jiang, BH; Lu, Y; Rojanasakul, Y; Schafer, R; Stueckle, TA; Wang, L	1
Andersen, ME; Chen, Y; Dong, J; Fu, J; Hou, Y; Pi, J; Qu, W; Tokar, EJ; Waalkes, MP; Wang, A; Woods, CG; Xu, Y; Xue, P; Yarborough, K; Zhan, L; Zhang, H; Zhang, Q	1
Hock, JM; Li, X; Liu, Y; Van Beneden, RJ	1
Cheng, HT; Guo, CY; Hu, HT; Li, HL; Luo, JP; Meng, YL; Xiao, JC; Yao, QJ	1
Chen, F; Jiang, M; Mo, BW; Wang, CM; Wang, JY; Zhao, XQ	1
Gao, G; Huo, J; Liu, Y; Shi, Y	1
Huang, C; Jiang, SJ; Lei, ML; Li, HC; Mu, XY; Wang, CX; Wang, LF	1
Brown, SL; Jiang, TT; Kim, JH	1
Wang, XW; Wei, L; Zuo, WS	1
Han, B; Kakudo, K; Tang, W; Wang, X; Zhang, J; Zhang, Q; Zhou, G	1
Li, BX; Lin, DH; Lin, LM; Xiao, JB; Yang, BF	1
Chang, LW; Cheng, Y; Tsou, TC	1
Jeong, ET; Kim, EJ; Kim, HR; Kim, SJ; Park, C; Park, R; So, HS; Yang, SH; Youn, MJ	1
An, S; Choe, TB; Hong, SI; Jin, HO; Kim, JI; Kwon, TJ; Lee, HC; Lee, SJ; Park, IC; Park, MJ; Rhee, CH; Seo, SK; Woo, SH; Yoo, DH; Yoon, SI	1
Fu, M; Li, Y; Liang, X; Lin, C; Qian, H; Wang, Y; Yu, J; Zhang, X	1
An, S; Choe, TB; Hong, SI; Jin, HO; Kim, ES; Kim, JI; Lee, HC; Lee, SJ; Park, IC; Rhee, CH; Seo, SK; Woo, SH; Yoo, DH	1
Li, B; Qu, GP; Shen, J; Xiu, QY	1
Björklund, NE; Nordberg, G; Pershagen, G	1
Hisanaga, A; Inamasu, T; Ishinishi, N; Yamamoto, A	1
Ishinihsi, N; Yamamoto, A	1
Hisanaga, A; Inamasu, T; Ishinishi, N	1
Lancashire, RJ; Sorahan, T	1
Aoyama, H; Harada, M; Hotta, N; Kurumatani, N; Nagira, T; Tsuda, T; Yamamoto, M	1
Aoyama, H; Kume, Y; Nagira, T; Tsuda, T; Yamamoto, M	1

Reviews

1 review(s) available for arsenic trioxide and Lung Neoplasms

Article	Year
A candidate for lung cancer treatment: arsenic trioxide. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2019, Volume: 21, Issue:9 Topics: Antineoplastic Agents; Arsenic Trioxide; Humans; Lung Neoplasms; Prognosis	2019

Trials

5 trial(s) available for arsenic trioxide and Lung Neoplasms

Article	Year
Arsenic trioxide transarterial chemoembolization with and without additional intravenous administration of arsenic trioxide in unresectable hepatocellular carcinoma with lung metastasis: a single-blind, randomized trial. Journal of cancer research and clinical oncology, 2015, Volume: 141, Issue:6 Topics: Adult; Aged; Analysis of Variance; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Biomarkers, Tumor; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; China; Combined Modality Therapy; Drug Administration Schedule; Female; Hepatic Artery; Humans; Infusions, Intravenous; Kaplan-Meier Estimate; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Oxides; Single-Blind Method; Treatment Outcome; Tumor Burden	2015
Patient-derived xenografts faithfully replicated clinical outcome in a phase II co-clinical trial of arsenic trioxide in relapsed small cell lung cancer. Journal of translational medicine, 2016, 05-03, Volume: 14, Issue:1 Topics: Aged; Aged, 80 and over; Animals; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Cisplatin; Electrophoresis; Female; Humans; Lung Neoplasms; Male; Mice, SCID; Middle Aged; Neoplasm Recurrence, Local; Oxides; Small Cell Lung Carcinoma; Subcutaneous Tissue; Treatment Outcome; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays	2016
Arsenic trioxide in patients with adenocarcinoma of the pancreas refractory to gemcitabine: a phase II trial of the University of Chicago Phase II Consortium. American journal of clinical oncology, 2008, Volume: 31, Issue:6 Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Deoxycytidine; Disease-Free Survival; Drug Resistance, Neoplasm; Gemcitabine; Humans; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Recurrence, Local; Oxides; Pancreatic Neoplasms; Salvage Therapy; Survival Rate; Treatment Outcome	2008
[Multicenter phase II clinical trial of arsenic trioxide injection in the treatment of primary hepatocarcinoma]. Zhonghua zhong liu za zhi [Chinese journal of oncology], 2011, Volume: 33, Issue:9 Topics: Adult; Aged; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Carcinoma, Hepatocellular; Disease Progression; Female; Follow-Up Studies; Half-Life; Humans; Injections; Leukopenia; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Nausea; Neoplasm Staging; Oxides; Quality of Life; Remission Induction; Survival Rate; Vomiting	2011
[The clinical therapeutic effects of arsenic trioxide combined with transcatheter arterial chemoembolization in treating primary liver cancer with pulmonary metastases]. Zhonghua nei ke za zhi, 2012, Volume: 51, Issue:12 Topics: Adult; Aged; Arsenic Trioxide; Arsenicals; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Combined Modality Therapy; Female; Humans; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Oxides; Treatment Outcome	2012

Other Studies

74 other study(ies) available for arsenic trioxide and Lung Neoplasms

Article	Year
Notch pathway inhibition mediated by arsenic trioxide depletes tumor initiating cells in small cell lung cancer. Molecular biology reports, 2022, Volume: 49, Issue:3 Topics: Animals; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Humans; Lung Neoplasms; Mice; Mice, Nude; Neoplastic Stem Cells; Small Cell Lung Carcinoma	2022
Identification of eIF6 as a prognostic factor that drives tumor progression and predicts arsenic trioxide efficacy in lung adenocarcinoma. Molecular biology reports, 2023, Volume: 50, Issue:2 Topics: Adenocarcinoma of Lung; Animals; Arsenic Trioxide; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Lung; Lung Neoplasms; Mice; Prognosis	2023
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2023, Volume: 25, Issue:7 Topics: Animals; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Cell Line, Tumor; Cell Proliferation; Heterografts; Humans; Ki-67 Antigen; Lung Neoplasms; Mice; RNA, Messenger; Xenograft Model Antitumor Assays	2023
Arsenic trioxide elicits anti-tumor activity by inhibiting polarization of M2-like tumor-associated macrophages via Notch signaling pathway in lung adenocarcinoma. International immunopharmacology, 2023, Volume: 117 Topics: Adenocarcinoma of Lung; Animals; Arsenic Trioxide; Cell Line, Tumor; Humans; Lung Neoplasms; Macrophages; Mice; Signal Transduction; Tumor Microenvironment; Tumor-Associated Macrophages	2023
MDM2-mediated Inhibitory Effect of Arsenic Trioxide on Small Cell Lung Cancer Cell Line by Degrading Mutant p53. Anti-cancer agents in medicinal chemistry, 2023, Volume: 23, Issue:16 Topics: Animals; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Cell Proliferation; Humans; Lung Neoplasms; Mice; Oxides; Proto-Oncogene Proteins c-mdm2; Small Cell Lung Carcinoma; Tumor Suppressor Protein p53	2023
Combination of Arsenic Trioxide and Valproic Acid Efficiently Inhibits Growth of Lung Cancer Cells via G2/M-Phase Arrest and Apoptotic Cell Death. International journal of molecular sciences, 2020, Apr-10, Volume: 21, Issue:7 Topics: Animals; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Biomarkers; Cell Line, Tumor; Disease Models, Animal; Drug Synergism; G2 Phase Cell Cycle Checkpoints; Humans; Lung Neoplasms; Membrane Potential, Mitochondrial; Mice; Valproic Acid; Xenograft Model Antitumor Assays	2020
Targeting positive feedback between BASP1 and EGFR as a therapeutic strategy for lung cancer progression. Theranostics, 2020, Volume: 10, Issue:24 Topics: Adenocarcinoma of Lung; Animals; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Brain; Brain Neoplasms; Cell Line, Tumor; Cell Membrane; Drug Resistance, Neoplasm; ErbB Receptors; Feedback, Physiological; Gene Expression Profiling; Gene Knockdown Techniques; Humans; Kaplan-Meier Estimate; Lung; Lung Neoplasms; Membrane Proteins; Mice; Mutation; Nerve Tissue Proteins; Prognosis; Protein Kinase Inhibitors; Proteolysis; Repressor Proteins; Signal Transduction; Tissue Array Analysis; Xenograft Model Antitumor Assays	2020
Tetraarsenic hexoxide enhances generation of mitochondrial ROS to promote pyroptosis by inducing the activation of caspase-3/GSDME in triple-negative breast cancer cells. Cell death & disease, 2021, 02-08, Volume: 12, Issue:2 Topics: Animals; Antineoplastic Agents; Arsenic Trioxide; Caspase 3; Cell Line, Tumor; Enzyme Activation; Female; Humans; Lung Neoplasms; Mice, Inbred BALB C; Mitochondria; Oxidative Stress; Phosphorylation; Pyroptosis; Reactive Oxygen Species; Receptors, Estrogen; Signal Transduction; STAT3 Transcription Factor; Triple Negative Breast Neoplasms	2021
Extracellular signal-regulated kinase 8-mediated NF-κB activation increases sensitivity of human lung cancer cells to arsenic trioxide. Oncotarget, 2017, Jul-25, Volume: 8, Issue:30 Topics: Active Transport, Cell Nucleus; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Drug Resistance, Neoplasm; Extracellular Signal-Regulated MAP Kinases; Humans; Lung Neoplasms; NF-kappa B; Oxides; Phosphorylation; Protein Binding; Proteolysis; Substrate Specificity	2017
miR-155 mediates arsenic trioxide resistance by activating Nrf2 and suppressing apoptosis in lung cancer cells. Scientific reports, 2017, 09-22, Volume: 7, Issue:1 Topics: Adenocarcinoma of Lung; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Cell Line, Tumor; Drug Resistance, Neoplasm; Humans; Lung Neoplasms; MicroRNAs; NF-E2-Related Factor 2; Signal Transduction	2017
[miR-155/BACH1 Signaling Pathway in Human Lung Adenocarcinoma Cell Death Induced by Arsenic Trioxide]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2017, Volume: 48, Issue:6 Topics: Adenocarcinoma; Adenocarcinoma of Lung; Apoptosis; Arsenic Trioxide; Arsenicals; Basic-Leucine Zipper Transcription Factors; Cell Death; Cell Line, Tumor; Heme Oxygenase-1; Humans; Lung Neoplasms; MicroRNAs; NAD(P)H Dehydrogenase (Quinone); Oxides; Signal Transduction	2017
Arsenic Trioxide Suppresses Tumor Growth through Antiangiogenesis via Notch Signaling Blockade in Small-Cell Lung Cancer. BioMed research international, 2019, Volume: 2019 Topics: Adaptor Proteins, Signal Transducing; Angiogenesis Inhibitors; Animals; Arsenic Trioxide; Calcium-Binding Proteins; Cell Line, Tumor; Cell Proliferation; Collagen; Down-Regulation; Drug Combinations; Human Umbilical Vein Endothelial Cells; Humans; Intercellular Signaling Peptides and Proteins; Laminin; Lentivirus; Lung Neoplasms; Male; Mice, Nude; Proteoglycans; Receptors, Notch; Signal Transduction; Small Cell Lung Carcinoma; Transcription Factor HES-1; Up-Regulation; Xenograft Model Antitumor Assays	2019
Arsenic trioxide inhibits liver cancer stem cells and metastasis by targeting SRF/MCM7 complex. Cell death & disease, 2019, 06-11, Volume: 10, Issue:6 Topics: Animals; Antineoplastic Agents; Arsenic Trioxide; Carcinoma, Hepatocellular; Cell Line, Tumor; Disease Progression; Down-Regulation; Gene Expression Regulation, Neoplastic; Gene Ontology; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Mice; Mice, Inbred NOD; Mice, Nude; Mice, SCID; Minichromosome Maintenance Complex Component 7; Neoplastic Stem Cells; Prognosis; Serum Response Factor; Transplantation, Heterologous	2019
Combination of arsenic trioxide and chemotherapy in small cell lung cancer. Lung cancer (Amsterdam, Netherlands), 2013, Volume: 82, Issue:2 Topics: Animals; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Cell Proliferation; Cisplatin; Disease Models, Animal; DNA Damage; Drug Synergism; Etoposide; Female; Glutathione; Humans; Lung Neoplasms; Membrane Potential, Mitochondrial; Mice; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Oxides; Reactive Oxygen Species; Small Cell Lung Carcinoma; Xenograft Model Antitumor Assays	2013
Arsenic trioxide co-exposure potentiates benzo(a)pyrene genotoxicity by enhancing the oxidative stress in human lung adenocarcinoma cell. Biological trace element research, 2013, Volume: 156, Issue:1-3 Topics: Adenocarcinoma; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Benzo(a)pyrene; Cell Line, Tumor; DNA Damage; Drug Synergism; Humans; Lung Neoplasms; Oxidative Stress; Oxides	2013
Targeting of the Hedgehog signal transduction pathway suppresses survival of malignant pleural mesothelioma cells in vitro. The Journal of thoracic and cardiovascular surgery, 2014, Volume: 147, Issue:1 Topics: Anilides; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Hedgehog Proteins; Humans; Itraconazole; Lung Neoplasms; Mesothelioma; Mesothelioma, Malignant; Molecular Targeted Therapy; Oxides; Pleural Neoplasms; Pyridines; Pyrimidines; Receptors, G-Protein-Coupled; RNA Interference; Signal Transduction; Smoothened Receptor; Time Factors; Transcription Factors; Transfection; Zinc Finger Protein GLI1	2014
Indomethacin-enhanced anticancer effect of arsenic trioxide in A549 cell line: involvement of apoptosis and phospho-ERK and p38 MAPK pathways. BioMed research international, 2013, Volume: 2013 Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; bcl-2-Associated X Protein; Caspase 3; Celecoxib; Cell Proliferation; Cyclooxygenase 2; Dexamethasone; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Neoplastic; Humans; Indomethacin; Lung Neoplasms; MAP Kinase Signaling System; Oxides; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyrazoles; RNA, Messenger; Sulfonamides; Time Factors	2013
Improved apoptotic cell death in drug-resistant non-small-cell lung cancer cells by tumor necrosis factor-related apoptosis-inducing ligand-based treatment. The Journal of pharmacology and experimental therapeutics, 2014, Volume: 348, Issue:3 Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Benzophenanthridines; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cisplatin; DNA Damage; Drug Resistance, Neoplasm; Drug Synergism; Humans; Isoquinolines; Lung Neoplasms; Oxides; Receptors, TNF-Related Apoptosis-Inducing Ligand; TNF-Related Apoptosis-Inducing Ligand	2014
Downregulation of thymidylate synthase with arsenic trioxide in lung adenocarcinoma. International journal of oncology, 2014, Volume: 44, Issue:6 Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Survival; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Liver Neoplasms, Experimental; Lung Neoplasms; Mice; Mice, Nude; Oxides; Thymidylate Synthase; Xenograft Model Antitumor Assays	2014
Arsenic trioxide: marked suppression of tumor metastasis potential by inhibiting the transcription factor Twist in vivo and in vitro. Journal of cancer research and clinical oncology, 2014, Volume: 140, Issue:7 Topics: Animals; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Carcinoma, Hepatocellular; Cell Line, Tumor; Down-Regulation; Embolization, Therapeutic; Liver Neoplasms; Lung Neoplasms; Male; Neoplasm Metastasis; Oxides; Rats; Rats, Inbred BUF; Twist-Related Protein 1	2014
Nutlin-3 overcomes arsenic trioxide resistance and tumor metastasis mediated by mutant p53 in Hepatocellular Carcinoma. Molecular cancer, 2014, May-31, Volume: 13 Topics: Animals; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Carcinoma, Hepatocellular; Cell Line, Tumor; DNA-Binding Proteins; Drug Resistance, Neoplasm; Drug Synergism; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Liver Neoplasms; Lung Neoplasms; Mice; Mice, Nude; Mutation; Neoplasm Transplantation; Nuclear Proteins; Oxides; Piperazines; Signal Transduction; Tumor Protein p73; Tumor Suppressor Protein p53; Tumor Suppressor Proteins	2014
Arsenic trioxide inhibits CXCR4-mediated metastasis by interfering miR-520h/PP2A/NF-κB signaling in cervical cancer. Annals of surgical oncology, 2014, Volume: 21 Suppl 4 Topics: Animals; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Proliferation; Chemokine CXCL12; Down-Regulation; Female; HeLa Cells; Humans; Lung Neoplasms; Mice; MicroRNAs; Neoplasm Invasiveness; NF-kappa B; Oxides; Protein Phosphatase 2; Receptors, CXCR4; RNA, Messenger; Signal Transduction; Transcription, Genetic; Uterine Cervical Neoplasms	2014
GLI2 is a novel therapeutic target for metastasis of osteosarcoma. International journal of cancer, 2015, Mar-15, Volume: 136, Issue:6 Topics: Adolescent; Adult; Animals; Arsenic Trioxide; Arsenicals; Bone Neoplasms; Cell Line, Tumor; Cell Movement; Child; Female; Hedgehog Proteins; Humans; Kruppel-Like Transcription Factors; Lung Neoplasms; Male; Mice; Neoplasm Invasiveness; Nuclear Proteins; Osteosarcoma; Oxides; Zinc Finger Protein Gli2	2015
Arsenic trioxide exerts anti-lung cancer activity by inhibiting angiogenesis. Current cancer drug targets, 2014, Volume: 14, Issue:6 Topics: Adaptor Proteins, Signal Transducing; Angiogenesis Inhibitors; Animals; Arsenic Trioxide; Arsenicals; Calcium-Binding Proteins; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Human Umbilical Vein Endothelial Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Intercellular Signaling Peptides and Proteins; Lung Neoplasms; Male; Mice, Inbred BALB C; Mice, Nude; Neovascularization, Pathologic; Oxides; Receptor, Notch1; Signal Transduction; Time Factors; Tumor Burden; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2; Xenograft Model Antitumor Assays	2014
E2F1 downregulation by arsenic trioxide in lung adenocarcinoma. International journal of oncology, 2014, Volume: 45, Issue:5 Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Cell Survival; E2F1 Transcription Factor; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mice; Oxides; United States; United States Food and Drug Administration; Xenograft Model Antitumor Assays	2014
Downregulation of thymidylate synthase and E2F1 by arsenic trioxide in mesothelioma. International journal of oncology, 2015, Volume: 46, Issue:1 Topics: Animals; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Down-Regulation; E2F1 Transcription Factor; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mesothelioma; Mesothelioma, Malignant; Mice; Mice, Inbred BALB C; Mice, Nude; Oxides; Thymidylate Synthase; Xenograft Model Antitumor Assays	2015
Efficacy of Arsenic Trioxide in the Treatment of Malignant Pleural Effusion Caused by Pleural Metastasis of Lung Cancer. Cell biochemistry and biophysics, 2015, Volume: 71, Issue:3 Topics: Animals; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Microvessels; Neoplasm Metastasis; NF-kappa B; Oxides; Permeability; Pleural Effusion, Malignant; Tumor Burden; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A	2015
Resveratrol synergistically triggers apoptotic cell death with arsenic trioxide via oxidative stress in human lung adenocarcinoma A549 cells. Biological trace element research, 2015, Volume: 163, Issue:1-2 Topics: Adenocarcinoma; Anticarcinogenic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Drug Synergism; Humans; Lung Neoplasms; Oxidative Stress; Oxides; Resveratrol; Stilbenes	2015
Arsenic trioxide-induced cytotoxicity in small cell lung cancer via altered redox homeostasis and mitochondrial integrity. International journal of oncology, 2015, Volume: 46, Issue:3 Topics: Antineoplastic Agents; Antioxidants; Apoptosis; Arsenic Trioxide; Arsenicals; Butylated Hydroxyanisole; Cell Death; Cell Line, Tumor; DNA Damage; Glutathione; Homeostasis; Humans; Lung Neoplasms; Mitochondria; Oxidation-Reduction; Oxides; Reactive Oxygen Species; Small Cell Lung Carcinoma; Thioredoxins	2015
ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction underlie apoptosis induced by resveratrol and arsenic trioxide in A549 cells. Chemico-biological interactions, 2016, Feb-05, Volume: 245 Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Drug Synergism; Endoplasmic Reticulum Stress; Humans; Lung; Lung Neoplasms; Mitochondria; Oxides; Reactive Oxygen Species; Resveratrol; Stilbenes	2016
[Treatment of refractory pulmonary metastases from hepatocellular carcinoma by transcatheter arterial chemoembolization using arsenic trioxide in combination with sorafinib]. Zhonghua zhong liu za zhi [Chinese journal of oncology], 2015, Volume: 37, Issue:12 Topics: Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Humans; Liver Neoplasms; Lung Neoplasms; Niacinamide; Oxides; Phenylurea Compounds; Sorafenib	2015
[Study on the resveratrol and arsenic trioxide combination induced apoptosis and its mechanism on lung adenocarcinoma cells]. Wei sheng yan jiu = Journal of hygiene research, 2016, Volume: 45, Issue:1 Topics: Adenocarcinoma; Adenocarcinoma of Lung; Anticarcinogenic Agents; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Arsenic Trioxide; Arsenicals; Buthionine Sulfoximine; Caspase 3; Drug Synergism; Glutathione; Humans; Lung Neoplasms; Membrane Potential, Mitochondrial; Mitochondria; Oxidation-Reduction; Oxides; Resveratrol; Stilbenes; Tumor Cells, Cultured	2016
Combination effects of arsenic trioxide and fibroblast growth factor receptor inhibitor in squamous cell lung carcinoma. Lung cancer (Amsterdam, Netherlands), 2016, Volume: 101 Topics: Animals; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Survival; Cysteine Proteinase Inhibitors; Drug Therapy, Combination; Female; Leupeptins; Lung Neoplasms; Mice; Mice, Nude; Oxides; Pyrimidines; Receptor, Fibroblast Growth Factor, Type 1; Xenograft Model Antitumor Assays	2016
Dihydroartemisinin Sensitizes Human Lung Adenocarcinoma A549 Cells to Arsenic Trioxide via Apoptosis. Biological trace element research, 2017, Volume: 179, Issue:2 Topics: A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Arsenic Trioxide; Arsenicals; Artemisinins; Bronchi; Cell Cycle Checkpoints; Cell Survival; DNA Damage; Epithelial Cells; Humans; Lung Neoplasms; Oxides; Reactive Oxygen Species	2017
Arsenic trioxide inhibits the growth of Calu-6 cells via inducing a G2 arrest of the cell cycle and apoptosis accompanied with the depletion of GSH. Cancer letters, 2008, Oct-18, Volume: 270, Issue:1 Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Caspase 3; Cell Line, Tumor; G2 Phase; Glutathione; Humans; Lung Neoplasms; Oxides; Reactive Oxygen Species; Superoxides	2008
Arsenic trioxide and auranofin inhibit selenoprotein synthesis: implications for chemotherapy for acute promyelocytic leukaemia. British journal of pharmacology, 2008, Volume: 154, Issue:5 Topics: Adenocarcinoma; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Arsenites; Auranofin; Cell Line, Tumor; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Leukemia, Promyelocytic, Acute; Lung Neoplasms; Oxides; Protein Biosynthesis; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Messenger; RNA, Small Interfering; Selenium Radioisotopes; Selenoproteins; Sodium Compounds; Sodium Selenite; Thioredoxin Reductase 1	2008
Induction of apoptosis in arsenic trioxide-treated lung cancer A549 cells by buthionine sulfoximine. Molecules and cells, 2008, Aug-31, Volume: 26, Issue:2 Topics: Apoptosis; Arsenic Trioxide; Arsenicals; Buthionine Sulfoximine; Cell Cycle; Cell Membrane; Cell Survival; Drug Resistance, Neoplasm; Drug Synergism; Glutathione; Humans; Lung Neoplasms; Membrane Potential, Mitochondrial; Oxides; Reactive Oxygen Species; Tumor Cells, Cultured	2008
Combination treatment with arsenic trioxide and sulindac enhances apoptotic cell death in lung cancer cells via activation of oxidative stress and mitogen-activated protein kinases. Oncology reports, 2008, Volume: 20, Issue:2 Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Arsenic Trioxide; Arsenicals; Blotting, Western; DNA Damage; Enzyme Inhibitors; Flow Cytometry; G1 Phase; Heme Oxygenase-1; Histones; Humans; Hydrogen Peroxide; JNK Mitogen-Activated Protein Kinases; Lung Neoplasms; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Oxidative Stress; Oxides; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Reactive Oxygen Species; Sulindac; Tumor Cells, Cultured	2008
The redox state of the lung cancer microenvironment depends on the levels of thioredoxin expressed by tumor cells and affects tumor progression and response to prooxidants. International journal of cancer, 2008, Oct-15, Volume: 123, Issue:8 Topics: Animals; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Carcinoma, Non-Small-Cell Lung; Cysteine; Disease Progression; Glutathione; HCT116 Cells; Humans; Intramolecular Oxidoreductases; Jurkat Cells; Lung Neoplasms; Macrophage Migration-Inhibitory Factors; Mice; Mice, SCID; Oxidation-Reduction; Oxides; Sulfhydryl Compounds; Thioredoxins	2008
Increased aquaglyceroporin 9 expression disrupts arsenic resistance in human lung cancer cells. Toxicology in vitro : an international journal published in association with BIBRA, 2009, Volume: 23, Issue:2 Topics: 8-Hydroxy-2'-Deoxyguanosine; Antineoplastic Agents; Aquaporins; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Deoxyguanosine; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Gene Expression Regulation, Neoplastic; Glutathione; Humans; Lung Neoplasms; Oxides	2009
Arsenic trioxide is highly cytotoxic to small cell lung carcinoma cells. Molecular cancer therapeutics, 2009, Volume: 8, Issue:1 Topics: Animals; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; bcl-2-Associated X Protein; Biomarkers; Caspase 3; Cell Death; Cell Differentiation; Cell Hypoxia; Cell Line, Tumor; Enzyme Activation; Female; Humans; Lung Neoplasms; Mice; Mice, Nude; Oxides; Small Cell Lung Carcinoma; Xenograft Model Antitumor Assays	2009
Lung cancer mortality in arsenic-exposed workers from a cadmium recovery plant. Occupational medicine (Oxford, England), 2009, Volume: 59, Issue:4 Topics: Aged, 80 and over; Arsenic Trioxide; Arsenicals; Cadmium; Cohort Studies; Colorado; Humans; Lung Neoplasms; Male; Occupational Diseases; Occupational Exposure; Oxides; Recycling; Time Factors	2009
Arsenic trioxide exerts synergistic effects with cisplatin on non-small cell lung cancer cells via apoptosis induction. Journal of experimental & clinical cancer research : CR, 2009, Aug-08, Volume: 28 Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Arsenic Trioxide; Arsenicals; Carcinoma, Non-Small-Cell Lung; Caspases; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cisplatin; Drug Synergism; Flow Cytometry; Humans; Lung Neoplasms; Oxides	2009
Arsenic trioxide inhibits metastatic potential of mouse hepatoma H22 cells in vitro and in vivo. Hepatobiliary & pancreatic diseases international : HBPD INT, 2009, Volume: 8, Issue:5 Topics: Animals; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Carcinoma, Hepatocellular; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Liver Neoplasms; Lung Neoplasms; Male; Matrix Metalloproteinase 2; Mice; NM23 Nucleoside Diphosphate Kinases; Oxides; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization	2009
Arsenic trioxide inhibits the growth of human lung cancer cell lines via cell cycle arrest and induction of apoptosis at both normoxia and hypoxia. Toxicology and industrial health, 2009, Volume: 25, Issue:8 Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Blotting, Western; CDC2 Protein Kinase; Cell Cycle; Cell Hypoxia; Cell Line; Cyclin B; Cyclin B1; Cyclin-Dependent Kinases; Down-Regulation; Humans; Lung Neoplasms; Oxides; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured	2009
The effect of MAPK inhibitors on arsenic trioxide-treated Calu-6 lung cells in relation to cell death, ROS and GSH levels. Anticancer research, 2009, Volume: 29, Issue:10 Topics: Adenocarcinoma; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Cell Cycle; Cell Growth Processes; Cell Line, Tumor; Drug Synergism; Glutathione; Humans; JNK Mitogen-Activated Protein Kinases; Lung Neoplasms; Membrane Potential, Mitochondrial; Mitogen-Activated Protein Kinases; Oxides; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Reactive Oxygen Species	2009
Effects of arsenic trioxide on cell death, reactive oxygen species and glutathione levels in different cell types. International journal of molecular medicine, 2010, Volume: 25, Issue:1 Topics: Adenocarcinoma; Animals; Arsenic Trioxide; Arsenicals; Cattle; Cell Death; Cell Line; Cell Line, Tumor; Cell Proliferation; Endothelial Cells; Glutathione; Growth Inhibitors; HeLa Cells; Humans; Lung Neoplasms; Oxides; Reactive Oxygen Species	2010
Arsenic trioxide modulates DNA synthesis and apoptosis in lung carcinoma cells. International journal of environmental research and public health, 2010, Volume: 7, Issue:5 Topics: Apoptosis; Arsenic Trioxide; Arsenicals; Caspase 3; Cell Cycle; Cell Line, Tumor; DNA Replication; Humans; Lung Neoplasms; Oxides; p38 Mitogen-Activated Protein Kinases; Thymidine	2010
Enhanced suppression of tumor growth by concomitant treatment of human lung cancer cells with suberoylanilide hydroxamic acid and arsenic trioxide. Toxicology and applied pharmacology, 2011, Nov-15, Volume: 257, Issue:1 Topics: Animals; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Comet Assay; DNA Damage; Drug Synergism; Drug Therapy, Combination; Flow Cytometry; Humans; Hydroxamic Acids; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Oxides; Vorinostat	2011
[Inhibitory effect of arsenic trioxide on the pulmonary metastasis of melanoma B16 cells]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2011, Volume: 31, Issue:10 Topics: Animals; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Oxides	2011
The SUMO E3-ligase PIAS1 regulates the tumor suppressor PML and its oncogenic counterpart PML-RARA. Cancer research, 2012, May-01, Volume: 72, Issue:9 Topics: Animals; Arsenic Trioxide; Arsenicals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Transformation, Neoplastic; HEK293 Cells; Humans; Lung Neoplasms; Nuclear Proteins; Oncogene Proteins, Fusion; Oxides; Polymorphism, Single Nucleotide; Promyelocytic Leukemia Protein; Protein Inhibitors of Activated STAT; Rats; Small Ubiquitin-Related Modifier Proteins; Transcription Factors; Transfection; Tumor Suppressor Proteins; Ubiquitin	2012
Chronic occupational exposure to arsenic induces carcinogenic gene signaling networks and neoplastic transformation in human lung epithelial cells. Toxicology and applied pharmacology, 2012, Jun-01, Volume: 261, Issue:2 Topics: Animals; Arsenic Trioxide; Arsenicals; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Epithelial Cells; Female; Gene Regulatory Networks; Humans; Lung; Lung Neoplasms; Mice; Mitochondria; Neoplasm Invasiveness; Occupational Exposure; Oligonucleotide Array Sequence Analysis; Oxides; PPAR alpha; Signal Transduction	2012
Regulatory role of KEAP1 and NRF2 in PPARγ expression and chemoresistance in human non-small-cell lung carcinoma cells. Free radical biology & medicine, 2012, Aug-15, Volume: 53, Issue:4 Topics: Antineoplastic Agents; Antioxidant Response Elements; Arsenic Trioxide; Arsenicals; Carcinoma, Non-Small-Cell Lung; Cell Differentiation; Cell Line, Tumor; Cell Survival; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Gene Expression Regulation; Gene Knockdown Techniques; Glutamate-Cysteine Ligase; Heme Oxygenase-1; Humans; Intracellular Signaling Peptides and Proteins; Kelch-Like ECH-Associated Protein 1; Lung Neoplasms; Models, Biological; NAD(P)H Dehydrogenase (Quinone); Neoplastic Stem Cells; NF-E2-Related Factor 2; Oxides; PPAR gamma; Proto-Oncogene Mas; RNA Interference; Rosiglitazone; Thiazolidinediones	2012
Aberrant overexpression of FOXM1 transcription factor plays a critical role in lung carcinogenesis induced by low doses of arsenic. Molecular carcinogenesis, 2014, Volume: 53, Issue:5 Topics: Adenocarcinoma; Adult; Animals; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Blotting, Western; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Dose-Response Relationship, Drug; Forkhead Box Protein M1; Forkhead Transcription Factors; Gene Expression Regulation; Gene Knockdown Techniques; Humans; Lung; Lung Neoplasms; Mice; Mice, SCID; Oxides; Polymorphism, Single Nucleotide; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering	2014
[Arsenic trioxide enhances TRAIL inducing human lung cancer cell line A549 cells apoptosis by down-regulate the expression of NF-kappaB]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2012, Volume: 43, Issue:6 Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; NF-kappa B; Oxides; TNF-Related Apoptosis-Inducing Ligand	2012
[Arsenic trioxide induced apoptosis and expression of p53 and bcl-2 genes in human small cell lung cancer cells]. Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 2002, Volume: 25, Issue:11 Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Carcinoma, Small Cell; Gene Expression; Genes, bcl-2; Genes, p53; Humans; Lung Neoplasms; Oxides; Tumor Cells, Cultured	2002
[Effect and mechanism of arsenic trioxide on chemosensitivity of human lung adenocarcinoma cells]. Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 2003, Volume: 26, Issue:11 Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Cycle; Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; Lung Neoplasms; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Oxides; Proto-Oncogene Proteins c-bcl-2; Vault Ribonucleoprotein Particles	2003
Combined effect of arsenic trioxide and sulindac sulfide in A549 human lung cancer cells in vitro. Journal of experimental & clinical cancer research : CR, 2004, Volume: 23, Issue:2 Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Arsenic Trioxide; Arsenicals; Humans; In Vitro Techniques; Lung Neoplasms; Oxides; Sulindac; Tumor Cells, Cultured; Tumor Stem Cell Assay	2004
[Toxicity of arsenic trioxide to human lung adenocarcinoma cell line SPCA1 and its mechanism]. Ai zheng = Aizheng = Chinese journal of cancer, 2004, Volume: 23, Issue:12 Topics: Adenocarcinoma; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Calcium; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; fas Receptor; Humans; Inhibitory Concentration 50; Lung Neoplasms; Oxides; Proto-Oncogene Proteins c-bcl-2	2004
Effect of arsenic trioxide (ATO) on human lung carcinoma PG cell line: ATO induced apoptosis of PG cells and decreased expression of Bcl-2, Pgp. Journal of experimental therapeutics & oncology, 2004, Volume: 4, Issue:4 Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Flow Cytometry; Humans; Immunohistochemistry; In Vitro Techniques; Lung Neoplasms; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Microscopy, Phase-Contrast; Oxides; Proto-Oncogene Proteins c-bcl-2; Time Factors	2004
Synergistic effect of all-trans-retinoic acid and arsenic trioxide on growth inhibition and apoptosis in human hepatoma, breast cancer, and lung cancer cells in vitro. World journal of gastroenterology, 2005, Sep-28, Volume: 11, Issue:36 Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Division; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Synergism; Glutathione; Glutathione Transferase; Humans; Lung Neoplasms; Oxides; Tretinoin	2005
Mitogen-activated protein kinases mediate arsenic-induced down-regulation of survivin in human lung adenocarcinoma cells. Archives of toxicology, 2006, Volume: 80, Issue:6 Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Drug Antagonism; Humans; Inhibitor of Apoptosis Proteins; Lung Neoplasms; Microtubule-Associated Proteins; Mitogen-Activated Protein Kinases; Neoplasm Proteins; Oxides; Poly(ADP-ribose) Polymerases; Survivin	2006
Combination treatment with arsenic trioxide and sulindac augments their apoptotic potential in lung cancer cells through activation of caspase cascade and mitochondrial dysfunction. International journal of oncology, 2006, Volume: 28, Issue:6 Topics: Apoptosis; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Flow Cytometry; Growth Inhibitors; Humans; Hydrogen Peroxide; Lung Neoplasms; Oxides; Sulindac	2006
Synergistic induction of apoptosis by sulindac and arsenic trioxide in human lung cancer A549 cells via reactive oxygen species-dependent down-regulation of survivin. Biochemical pharmacology, 2006, Nov-15, Volume: 72, Issue:10 Topics: Apoptosis; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Cell Survival; Down-Regulation; Drug Synergism; Humans; Inhibitor of Apoptosis Proteins; Lung Neoplasms; Microtubule-Associated Proteins; Neoplasm Proteins; Oxides; Reactive Oxygen Species; Sulindac; Survivin	2006
Arsenic trioxide (As2O3) reduces the invasive and metastatic properties of cervical cancer cells in vitro and in vivo. Gynecologic oncology, 2007, Volume: 106, Issue:2 Topics: Animals; Arsenic Trioxide; Arsenicals; beta Catenin; Cadherins; Caveolin 1; Cell Adhesion; Cell Line, Tumor; Cell Movement; Female; Growth Inhibitors; HeLa Cells; Humans; Lung Neoplasms; Mice; Mice, Inbred C57BL; Neoplasm Invasiveness; Neoplasm Metastasis; NF-kappa B; Oxides; Uterine Cervical Neoplasms	2007
A combination of sulindac and arsenic trioxide synergistically induces apoptosis in human lung cancer H1299 cells via c-Jun NH2-terminal kinase-dependent Bcl-xL phosphorylation. Lung cancer (Amsterdam, Netherlands), 2008, Volume: 61, Issue:3 Topics: Acetylcysteine; Apoptosis; Arsenic Trioxide; Arsenicals; bcl-X Protein; Carcinoma, Non-Small-Cell Lung; Caspases; Cell Line, Tumor; Drug Synergism; Humans; JNK Mitogen-Activated Protein Kinases; Lung Neoplasms; Membrane Potential, Mitochondrial; Mitochondria; Oxides; Phosphorylation; Reactive Oxygen Species; Signal Transduction; Sulindac	2008
[Effects of arsenic trioxide on apoptosis and proliferation of human lung cancer cells under hypoxia]. Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, 2008, Volume: 6, Issue:3 Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Humans; Lung Neoplasms; Oxides	2008
Carcinomas of the respiratory tract in hamsters given arsenic trioxide and/or benzo[a]pyrene by the pulmonary route. Environmental research, 1984, Volume: 34, Issue:2 Topics: Animals; Arsenic; Arsenic Trioxide; Arsenicals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Charcoal; Cricetinae; Drug Synergism; Dust; Lung Neoplasms; Male; Mesocricetus; Neoplasms, Experimental; Oxides	1984
Tumorigenicity of arsenic trioxide to the lung in Syrian golden hamsters by intermittent instillations. Cancer letters, 1983, Volume: 21, Issue:2 Topics: Adenoma; Animals; Arsenic; Arsenic Trioxide; Arsenicals; Cricetinae; Female; Lung Neoplasms; Mesocricetus; Oxides; Probability; Trachea	1983
Discrepancy between epidemiological evidence and animal experimental result. Journal of UOEH, 1983, Mar-20, Volume: 5 Suppl Topics: Adenoma; Animals; Arsenic; Arsenic Trioxide; Arsenicals; Carcinogens; Cricetinae; Female; Lung Neoplasms; Mesocricetus; Occupational Diseases; Oxides	1983
Comparison of arsenic trioxide and calcium arsenate retention in the rat lung after intratracheal instillation. Toxicology letters, 1982, Volume: 12, Issue:1 Topics: Animals; Arsenates; Arsenic; Arsenic Trioxide; Arsenicals; Lung; Lung Neoplasms; Male; Neoplasms, Experimental; Oxides; Rats; Rats, Inbred Strains	1982
Lung cancer mortality in a cohort of workers employed at a cadmium recovery plant in the United States: an analysis with detailed job histories. Occupational and environmental medicine, 1997, Volume: 54, Issue:3 Topics: Arsenic Trioxide; Arsenicals; Cadmium Compounds; Cohort Studies; Follow-Up Studies; Humans; Lung Neoplasms; Male; Metallurgy; Occupational Exposure; Oxides; Poisson Distribution; Risk Assessment; United States	1997
Malignant neoplasms among residents who drank well water contaminated by arsenic from a king's yellow factory. Journal of UOEH, 1989, Mar-20, Volume: 11 Suppl Topics: Adult; Aged; Arsenic; Arsenic Poisoning; Arsenic Trioxide; Arsenicals; Chemical Industry; Child; Cohort Studies; Drinking; Female; Humans; Japan; Lung Neoplasms; Male; Middle Aged; Neoplasms; Neoplasms, Multiple Primary; Oxides; Retrospective Studies; Smoking; Sulfides; Water Pollution, Chemical; Water Supply	1989
[A case of lung cancer associated with chronic arsenic poisoning caused by neighborhood exposure of As2O3 from Toroku mine]. Sangyo igaku. Japanese journal of industrial health, 1987, Volume: 29, Issue:3 Topics: Aged; Arsenic Poisoning; Arsenic Trioxide; Arsenicals; Carcinoma, Squamous Cell; Chronic Disease; Female; Humans; Lung Neoplasms; Mining; Occupational Diseases; Oxides	1987