arsenic trioxide has been researched along with Cell Transformation, Neoplastic in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (9.68) | 18.2507 |
| 2000's | 5 (16.13) | 29.6817 |
| 2010's | 22 (70.97) | 24.3611 |
| 2020's | 1 (3.23) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, Y; Li, S; Liu, S; Rao, Q; Tang, K; Tian, Z; Wang, J; Wang, M; Xing, H; Xu, Y; Yang, X | 1 |
| Grillari, J; Groza, D; Grusch, M; Heffeter, P; Kryeziu, K; Mildner, M; Nagelreiter, F; Rösinger, S; Schoenhacker-Alte, B; Schosserer, M; Tav, K; Tschachler, E; Weinmuellner, R; Wimmer, L; Zbiral, B | 1 |
| Chiu, JF; Huang, N; Li, G; Lin, W; Pei, X; Tao, T | 1 |
| Gao, J; Li, D; Lin, H; Luo, X; Mao, J; Shan, H; Su, Z; Wei, R; Zhang, K; Zhou, B | 1 |
| Chan, TC; Chang, WR; Chiou, SH; Fang, KM; Lin, TC; Liu, JJ; Ma, SZ; Tzeng, SF; Tzou, BC; Yang, CS | 1 |
| Ayoubi, HR; Bazarbachi, AA; Bitar, NM; De Thé, HB; El Eit, RM; Iskandarani, AN; Jabbour, MN; Mahfouz, RA; Mahon, FX; Nasr, RR; Saliba, JL; Zaatari, GS | 1 |
| Dos Santos, GA; Kats, L; Pandolfi, PP | 1 |
| de Thé, H; Rice, KL | 1 |
| Hasan, SK; Lo-Coco, F | 1 |
| Ablain, J; de Reynies, A; de Thé, H; Halftermeyer, J; Le Bras, M; Metzger, D; Peres, L; Vitaliano-Prunier, A | 1 |
| Huang, HS; Liu, ZM; Tseng, HY; Wu, WJ; Yeh, BW | 1 |
| Gao, B; Lu, M; Meng, X; Miao, Z; Qiao, X; Wu, L; Xue, D; Zhang, W | 1 |
| Brossart, P; Czarnocka, B; Fröhlich, E; Wahl, R | 1 |
| Cao, L; Dunlevy, JR; Garrett, SH; Sens, DA; Sens, MA; Somji, S; Zheng, Y; Zhou, XD | 1 |
| de Thé, H; Nasr, R | 1 |
| Kurokawa, M; Nagai, S; Takahashi, T | 1 |
| Beezhold, K; Castranova, V; Chen, F; Kan, H; Liu, J; Meighan, T; Shi, X | 1 |
| Chen, C; Edin, ML; Gong, W; Li, Y; Liu, L; Wang, DW; Zeldin, DC | 1 |
| Byers, LA; Carter, B; Chiang, CM; Girard, L; Heymach, JV; Konstantinidou, G; Rabellino, A; Rimessi, A; Scaglioni, PP; Teruya-Feldstein, J; Wu, SY | 1 |
| Chen, SJ; Chen, Z; Li, JM; Mi, JQ; Shen, ZX | 1 |
| Barnett, JB; Davis, ME; Holaskova, I; Jiang, BH; Lu, Y; Rojanasakul, Y; Schafer, R; Stueckle, TA; Wang, L | 1 |
| Bode, AM; Dong, Z; Kim, DJ; Kim, HG; Lee, KY; Li, S; Li, X | 1 |
| Shih, HM; Yang, WC | 1 |
| Hock, JM; Li, X; Liu, Y; Van Beneden, RJ | 1 |
| Beal, N; Diehl, LF; Huff, CA; Jones, RJ; Matsui, W; Smith, BD; Vala, M | 1 |
| Gogvadze, V; McConkey, DJ; Mirnikjoo, B; Nutt, LK; Orrenius, S; Uthaisang, W | 1 |
| Chen, GQ; Huang, Y; Jiang, Y; Liu, W; Peng, ZG; Song, LP; Zhao, Q | 1 |
| Horváth, V; Ondrousková, E; Smarda, J; Soucek, K | 1 |
| Chen, G; Shi, G; Tang, W | 1 |
| Ikeda, Y; Kinjo, K; Kizaki, M; Muto, A; Ueno, H | 1 |
| Zhang, T | 1 |
5 review(s) available for arsenic trioxide and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Synergy against PML-RARa: targeting transcription, proteolysis, differentiation, and self-renewal in acute promyelocytic leukemia.
Topics: Animals; Arsenic Trioxide; Arsenicals; Cell Differentiation; Cell Line, Tumor; Cell Transformation, Neoplastic; Gene Expression Regulation, Leukemic; Humans; Leukemia, Promyelocytic, Acute; Mice; Oncogene Proteins, Fusion; Oxides; Remission Induction; Signal Transduction; Transcriptional Activation; Tretinoin | 2013 |
Understanding the molecular pathogenesis of acute promyelocytic leukemia.
Topics: Animals; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Cell Differentiation; Cell Transformation, Neoplastic; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Clinical Trials as Topic; Disease Models, Animal; DNA End-Joining Repair; Drug Synergism; Granulocyte Precursor Cells; Humans; Leukemia, Promyelocytic, Acute; Mice; Molecular Targeted Therapy; Neoplasm Proteins; Neoplasms, Second Primary; Neoplastic Stem Cells; Oncogene Proteins, Fusion; Oxides; Signal Transduction; Topoisomerase II Inhibitors; Translocation, Genetic; Tretinoin | 2014 |
The impact of molecularly targeted therapies upon the understanding of leukemogenesis and the role of hematopoietic stem cell transplantation in acute promyelocytic leukemia.
Topics: Animals; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Differentiation; Cell Survival; Cell Transformation, Neoplastic; Glutamates; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Promyelocytic, Acute; Myeloid Progenitor Cells; Neoplastic Stem Cells; Nuclear Proteins; Oxides; Prodrugs; Promyelocytic Leukemia Protein; Transcription Factors; Tretinoin; Tumor Suppressor Proteins | 2010 |
How to manage acute promyelocytic leukemia.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Cell Transformation, Neoplastic; Central Nervous System Neoplasms; Consolidation Chemotherapy; Drug Synergism; Humans; Induction Chemotherapy; Leukemia, Promyelocytic, Acute; Maintenance Chemotherapy; Oxides; Recurrence; Tretinoin | 2012 |
Hypoxia inducible factor-1alpha and leukemic cell differentiation.
Topics: Animals; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Cell Transformation, Neoplastic; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Leukemia; Leukemia, Promyelocytic, Acute; Oxides | 2006 |
26 other study(ies) available for arsenic trioxide and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
A novel fusion protein TBLR1-RARα acts as an oncogene to induce murine promyelocytic leukemia: identification and treatment strategies.
Topics: Animals; Antineoplastic Agents; Arsenic Trioxide; Cell Differentiation; Cell Transformation, Neoplastic; Cells, Cultured; Female; HEK293 Cells; Histone Deacetylase Inhibitors; Humans; Leukemia, Promyelocytic, Acute; Male; Mice; Mice, Inbred C57BL; Oncogene Proteins, Fusion; Receptors, Cytoplasmic and Nuclear; Repressor Proteins; Retinoic Acid Receptor alpha; Xenograft Model Antitumor Assays | 2021 |
Long-term exposure of immortalized keratinocytes to arsenic induces EMT, impairs differentiation in organotypic skin models and mimics aspects of human skin derangements.
Topics: Animals; Arsenic; Arsenic Trioxide; Cell Culture Techniques; Cell Differentiation; Cell Transformation, Neoplastic; Epithelial-Mesenchymal Transition; Female; Humans; Keratinocytes; Mice, Inbred Strains; Organ Culture Techniques; Skin; Toxicity Tests, Chronic; Xenograft Model Antitumor Assays | 2018 |
DNA methylation of a non-CpG island promoter represses NQO1 expression in rat arsenic-transformed lung epithelial cells.
Topics: Animals; Arsenic Trioxide; Arsenicals; Azacitidine; Cell Line, Transformed; Cell Transformation, Neoplastic; CpG Islands; Decitabine; DNA Methylation; Enzyme Inhibitors; Epithelial Cells; Gene Expression Regulation; Lung; NAD(P)H Dehydrogenase (Quinone); Oxides; Promoter Regions, Genetic; Rats | 2018 |
An extracellular pH-driven targeted multifunctional manganese arsenite delivery system for tumor imaging and therapy.
Topics: Animals; Arsenic Trioxide; Cell Line, Tumor; Cell Transformation, Neoplastic; Drug Carriers; Drug Liberation; Extracellular Space; Humans; Hydrogen-Ion Concentration; Leukemia, Promyelocytic, Acute; Magnetic Resonance Imaging; Manganese; Mice; Nanoparticles; Peptides; Silicon Dioxide | 2019 |
Enhanced cell growth and tumorigenicity of rat glioma cells by stable expression of human CD133 through multiple molecular actions.
Topics: AC133 Antigen; Animals; Antigens, CD; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Basic Helix-Loop-Helix Transcription Factors; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Formazans; Gene Expression Regulation, Neoplastic; Glioma; Glycoproteins; GTPase-Activating Proteins; Homeodomain Proteins; Humans; Intercellular Signaling Peptides and Proteins; Lentivirus; Oncogene Protein v-akt; Oxides; Peptides; Rats; Rats, Sprague-Dawley; Receptor, Notch1; RNA, Messenger; RNA, Small Interfering; Tetrazolium Salts; Time Factors; Transcription Factor HES-1; Transfection; Tumor Stem Cell Assay | 2013 |
Effective targeting of chronic myeloid leukemia initiating activity with the combination of arsenic trioxide and interferon alpha.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Benzamides; Bone Marrow Transplantation; Cell Transformation, Neoplastic; Humans; Imatinib Mesylate; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Mice, Inbred BALB C; Oxides; Piperazines; Prognosis; Pyrimidines; Real-Time Polymerase Chain Reaction; Survival Rate; Tumor Cells, Cultured; Tumor Stem Cell Assay | 2014 |
The acute promyelocytic leukaemia success story: curing leukaemia through targeted therapies.
Topics: Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Cell Transformation, Neoplastic; Epigenesis, Genetic; Humans; Leukemia, Promyelocytic, Acute; Molecular Targeted Therapy; Oxides; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoid X Receptor alpha; Signal Transduction; Tretinoin | 2014 |
Clearance of PML/RARA-bound promoters suffice to initiate APL differentiation.
Topics: Animals; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Cell Differentiation; Cell Line, Tumor; Cell Transformation, Neoplastic; Cells, Cultured; Chlorocebus aethiops; COS Cells; Gene Expression Profiling; Humans; Leukemia, Promyelocytic, Acute; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Nude; Mice, Transgenic; Oncogene Proteins, Fusion; Oxides; Promoter Regions, Genetic; Protein Binding; Retinoid X Receptor alpha; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Sumoylation; Transcriptional Activation; Tretinoin | 2014 |
TG-interacting factor mediates arsenic-induced malignant transformation of keratinocytes via c-Src/EGFR/AKT/FOXO3A and redox signalings.
Topics: Animals; Arsenic Trioxide; Arsenicals; Cell Line; Cell Transformation, Neoplastic; CSK Tyrosine-Protein Kinase; Dose-Response Relationship, Drug; ErbB Receptors; Forkhead Box Protein O3; Forkhead Transcription Factors; Gene Knockdown Techniques; Homeodomain Proteins; Humans; Keratinocytes; Mice; NIH 3T3 Cells; Oxidation-Reduction; Oxides; Proto-Oncogene Proteins c-akt; Repressor Proteins; Signal Transduction; src-Family Kinases | 2015 |
Analysis of the transcriptional regulation of cancer-related genes by aberrant DNA methylation of the cis-regulation sites in the promoter region during hepatocyte carcinogenesis caused by arsenic.
Topics: Amino Acid Motifs; Arsenic Trioxide; Arsenicals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Carcinogenesis; Cell Line; Cell Transformation, Neoplastic; Computational Biology; DNA Methylation; Gene Expression Regulation, Neoplastic; Hepatocytes; Humans; Liver; Liver Neoplasms; Oligonucleotide Array Sequence Analysis; Oxides; Promoter Regions, Genetic; RNA, Messenger; Signal Transduction; Transcription Factors; Transcriptional Activation; Wnt Proteins | 2015 |
Antitumor effects of arsenic trioxide in transformed human thyroid cells.
Topics: Adenocarcinoma, Follicular; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Biological Transport, Active; Carcinoma, Papillary; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Glucose; Glutathione; Humans; Iodides; Iodine Radioisotopes; Oncogene Protein v-akt; Oxides; Phosphatidylinositol 3-Kinases; Radiation Tolerance; Reactive Oxygen Species; Thyroid Neoplasms | 2008 |
Keratin 6 expression correlates to areas of squamous differentiation in multiple independent isolates of As(+3)-induced bladder cancer.
Topics: Animals; Arsenic Trioxide; Arsenicals; Biomarkers, Tumor; Carcinogens; Carcinoma, Transitional Cell; Cell Line, Transformed; Cell Line, Tumor; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Humans; Keratin-6; Mice; Mice, Nude; Neoplasm Transplantation; Oxides; Urinary Bladder Neoplasms; Urothelium | 2010 |
Eradication of acute promyelocytic leukemia-initiating cells by PML/RARA-targeting.
Topics: Animals; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Granulocyte Precursor Cells; Humans; Leukemia, Promyelocytic, Acute; Mice; Oncogene Proteins, Fusion; Oncogenes; Oxides; Tretinoin | 2010 |
miR-190-mediated downregulation of PHLPP contributes to arsenic-induced Akt activation and carcinogenesis.
Topics: Arsenic Poisoning; Arsenic Trioxide; Arsenicals; Bronchi; Carcinogens, Environmental; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Down-Regulation; Epithelial Cells; Gene Expression Regulation; Gene Silencing; Humans; MicroRNAs; Nuclear Proteins; Oxides; Phosphoprotein Phosphatases; RNA, Messenger; Talin | 2011 |
Epoxyeicosatrienoic acids attenuate reactive oxygen species level, mitochondrial dysfunction, caspase activation, and apoptosis in carcinoma cells treated with arsenic trioxide.
Topics: 8,11,14-Eicosatrienoic Acid; Antineoplastic Agents; Antioxidants; Apoptosis; Arsenic Trioxide; Arsenicals; Caspase Inhibitors; Caspases; Cell Line, Tumor; Cell Transformation, Neoplastic; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Screening Assays, Antitumor; Drug Synergism; Enzyme Activation; HEK293 Cells; Humans; Indazoles; Membrane Potential, Mitochondrial; Mitochondria; Nitrofurans; Oxides; Reactive Oxygen Species | 2011 |
The SUMO E3-ligase PIAS1 regulates the tumor suppressor PML and its oncogenic counterpart PML-RARA.
Topics: Animals; Arsenic Trioxide; Arsenicals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Transformation, Neoplastic; HEK293 Cells; Humans; Lung Neoplasms; Nuclear Proteins; Oncogene Proteins, Fusion; Oxides; Polymorphism, Single Nucleotide; Promyelocytic Leukemia Protein; Protein Inhibitors of Activated STAT; Rats; Small Ubiquitin-Related Modifier Proteins; Transcription Factors; Transfection; Tumor Suppressor Proteins; Ubiquitin | 2012 |
Chronic occupational exposure to arsenic induces carcinogenic gene signaling networks and neoplastic transformation in human lung epithelial cells.
Topics: Animals; Arsenic Trioxide; Arsenicals; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Epithelial Cells; Female; Gene Regulatory Networks; Humans; Lung; Lung Neoplasms; Mice; Mitochondria; Neoplasm Invasiveness; Occupational Exposure; Oligonucleotide Array Sequence Analysis; Oxides; PPAR alpha; Signal Transduction | 2012 |
Polycomb (PcG) proteins, BMI1 and SUZ12, regulate arsenic-induced cell transformation.
Topics: 3T3 Cells; Animals; Arsenic; Arsenic Trioxide; Arsenicals; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p16; Gene Expression Regulation, Neoplastic; Histones; Humans; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Oxides; Polycomb Repressive Complex 1; Polycomb Repressive Complex 2; Polycomb-Group Proteins; Proto-Oncogene Proteins; Signal Transduction | 2012 |
The deubiquitinating enzyme USP37 regulates the oncogenic fusion protein PLZF/RARA stability.
Topics: Animals; Arsenic Trioxide; Arsenicals; Cell Differentiation; Cell Transformation, Neoplastic; Endopeptidases; Gene Expression Regulation, Leukemic; Humans; Leukemia, Promyelocytic, Acute; Mice; Oncogene Proteins, Fusion; Oxides; Protein Stability; Translocation, Genetic | 2013 |
Aberrant overexpression of FOXM1 transcription factor plays a critical role in lung carcinogenesis induced by low doses of arsenic.
Topics: Adenocarcinoma; Adult; Animals; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Blotting, Western; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Dose-Response Relationship, Drug; Forkhead Box Protein M1; Forkhead Transcription Factors; Gene Expression Regulation; Gene Knockdown Techniques; Humans; Lung; Lung Neoplasms; Mice; Mice, SCID; Oxides; Polymorphism, Single Nucleotide; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering | 2014 |
Requirement for myeloid growth factors in the differentiation of acute promyelocytic leukaemia.
Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Bryostatins; Cell Cycle; Cell Line, Tumor; Cell Transformation, Neoplastic; Flow Cytometry; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Inhibitors; Humans; Leukemia, Promyelocytic, Acute; Macrolides; Myelopoiesis; Oxides; Tretinoin | 2005 |
Indirect effects of Bax and Bak initiate the mitochondrial alterations that lead to cytochrome c release during arsenic trioxide-induced apoptosis.
Topics: Animals; Apoptosis; Arsenic Trioxide; Arsenicals; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Caspase 3; Caspases; Cell Line, Transformed; Cell Transformation, Neoplastic; Cells, Cultured; Cytochrome c Group; Dose-Response Relationship, Drug; Embryo, Mammalian; Fibroblasts; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Mitochondria, Liver; Necrosis; Oxidative Stress; Oxides; Reactive Oxygen Species; Superoxides | 2005 |
Alternative pathways of programmed cell death are activated in cells with defective caspase-dependent apoptosis.
Topics: Animals; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Autophagy; Blotting, Western; Camptothecin; Caspases; Cell Line, Transformed; Cell Transformation, Neoplastic; Chickens; Cycloheximide; Genes, myb; Humans; Microscopy, Fluorescence; Necrosis; Oxides; Signal Transduction; U937 Cells | 2008 |
[Double effects of arsenic trioxide (As2O3) on acute promyelocytic leukemic cell line].
Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Transformation, Neoplastic; Humans; Leukemia, Promyelocytic, Acute; Oncogene Proteins, Fusion; Oxides; Tumor Cells, Cultured | 1997 |
Application of heavy metal and cytokine for differentiation-inducing therapy in acute promyelocytic leukemia.
Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Differentiation; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Promyelocytic, Acute; Oxides; Tretinoin; Tumor Cells, Cultured | 1998 |
[Cell differentiation and apoptosis of tumor cells].
Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Transformation, Neoplastic; Humans; Leukemia, Promyelocytic, Acute; Oxides | 1999 |