Compounds > arsenic trioxide
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arsenic trioxide and Breast Neoplasms

arsenic trioxide has been researched along with Breast Neoplasms in 44 studies

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (2.27)18.2507
2000's11 (25.00)29.6817
2010's29 (65.91)24.3611
2020's3 (6.82)2.80

Authors

AuthorsStudies
Bashash, D; Ghaffari, SH; Kabuli, M; Kashani, B; Mousavi, SA; Nasrollahzadeh, A; Zaghal, A; Zandi, Z1
Bae, IJ; Bunch, H; Calderwood, SK; Cho, DH; Kang, K; Kim, D; Park, NY1
Chen, XJ; Fan, XD; Li, FZ; Piao, JG; Wang, BH; Wei, YH; Zhang, BB; Zheng, HS; Zheng, HY; Zhu, JJ1
Cao, T; Huang, H; Lian, C; Ma, J; Shi, Y; Wang, Z; Xia, J; Yang, Y1
Alshammari, GM; Aristatile, B; Arun, V; Dharuman, V; Nithyananthan, S; Preedia Babu, E; Sharma, P; Subastri, A; Suyavaran, A; Thirunavukkarasu, C1
Arenkiel, BR; Bado, I; Du, S; Goldstein, A; Gugala, Z; Li, Z; Liu, J; Rowley, DR; Tian, L; Wang, H; Wong, STC; Yang, M; Zhang, W; Zhang, XH; Zhao, H1
Alimoghaddam, K; Ghaffari, SH; Ghanizadeh-Vesali, S; Ghavamzadeh, A; Mojarrad, M; Yousefi, M; Zekri, A1
Annis, MG; Dong, Z; Guilbert, C; Mann, KK; Miller, WH; Siegel, PM1
Hu, C; Jiang, F; Li, Y; Li, Z; Mu, J; Ning, S; Si, L; Wang, X; Ye, X1
Chen, G; Duan, C; Gu, H; Gu, X; Liang, X; Liu, C; Luo, M; Wang, D; Zhang, H; Zhao, X; Zhao, Z1
Honma, Y; Kasukabe, T; Kato, N; Kumakura, S; Okabe-Kado, J1
An, B; Hao, Y; Li, L; Song, G; Wang, L; Wang, Y; Wei, T; Yin, C1
Armat, M; Bakhshaiesh, TO; Baradaran, B; Hejazi, MS; Samadi, N; Shanehbandi, D; Sharifi, S1
Chen, J; Cheng, L; Fang, B; Hong, H; Ma, C; Ma, J; Pang, H; Shi, Y; Wang, Z; Xia, J; Zeng, F; Zhang, S1
Choe, TB; Hong, SE; Jin, HO; Kim, EK; Kim, HA; Lee, JK; Lee, YH; Noh, WC; Oh, ST; Park, IC; Seong, MK; Woo, SH; Ye, SK; Yun, SM1
Ablain, J; de Thé, H; Esnault, C; Lehmann-Che, J; Poirot, B1
Akbari, ME; Bashash, D; Bayati, S; Ghaffari, SH; Nooshinfar, E; Rezaei-Tavirani, M; Safaroghli-Azar, A1
Aldaz, P; Anguita, J; Aransay, AM; Arreal, L; Arruabarrena-Aristorena, A; Barrio, R; Baselga, J; Caldas, C; Caro-Maldonado, A; Carracedo, A; Cortazar, AR; Domenici, G; Fernández-Ruiz, S; Garcia, S; Gomis, RR; Guiu, M; Ibrahim, YH; Iovanna, JL; Lawrie, CH; Macías, I; Martín-Martín, N; Martínez-Chantar, ML; Matheu, A; Piva, M; Planet, E; Radosevic-Robin, N; Rueda, OM; Salvador, F; Sánchez-Mosquera, P; Scaltriti, M; Serra, V; Sutherland, JD; Torrano, V; Urosevic, J; Valcárcel-Jiménez, L; Varela-Rey, M; Vivanco, Md; Zabala-Letona, A; Zúñiga-García, P1
Ahn, R; Chen, H; O'Halloran, TV; Thompson, DH; Van den Bossche, J1
Gao, P; Han, Y; He, T; Lin, F; Long, M; Ren, JH; Wang, X; Wei, JX; Yan, L; Zhang, HZ1
Ahn, RW; Chen, F; Chen, H; Clogston, JD; Cryns, VL; O'Halloran, TV; Parimi, V; Patri, AK; Raja, MR; Stern, ST; Swindell, EP1
Printz, C1
Fan, Q; Lu, SH; Ma, Z; Wang, F; Wang, L; Wang, R; Wu, X; Yang, J; Zhang, W1
Li, A; Shen, L; Xu, W; Ye, J; Zhou, J1
Flomenberg, N; Goldberg, A; Howell, A; Ko, YH; Lin, Z; Lisanti, MP; Martinez-Outschoorn, UE; Pavlides, S; Pestell, RG; Sotgia, F; Wang, C1
Blackburn, AC; Board, PG; Sun, RC1
Du, J; Hu, C; Jiang, F; Li, Z; Liu, H; Qi, H; Wang, X; Wang, Y; Zhong, C; Zhou, N1
Liu, H; Ma, F; Qiu, J; Tao, X; Wang, M; Wu, C1
Ahmad, A; Bao, B; Chen, Z; Li, Y; Mei, C; Miele, L; Sarkar, FH; Wang, Z; Xia, J; Yang, Q1
Li, YJ; Xia, J; Zhao, R1
Gong, Y; Jiang, G; Li, H; Liu, H; Liu, W; Wu, Y; Zhan, S1
Alhasan, MK; Lewis, MA; Liu, L; Magnusson, J; Mason, RP1
Fan, QX; Wang, F; Wang, LX; Wang, R; Wu, XA; Xu, DF; Zhang, WJ1
Kong, L; Wang, X; Yang, P; Zhao, J1
Chang, HH; Chang, KH; Chen, HW; Chen, YJ; Chung, CH; Huang, MJ; Lai, YL; Lin, LH; Su, WH; Wang, WY1
Dryden, MJ; Estey, E; Faderl, S; Garcia-Manero, G; Giles, F; Kantarjian, HM; Pierce, S; Ratnam, S; Tsimberidou, AM; Whitman, GJ1
Chan, JY; Chow, SK; Fung, KP2
Adrian, TE; Ding, X; Li, X1
Song, XR; Wang, XW; Wei, L; Zuo, WS1
Li, BX; Lin, DH; Lin, LM; Xiao, JB; Yang, BF1
Alemany, M; Caen, JP; Han, ZC; Levin, J; Lu, M; Sequeira-Le Grand, A; Sulpice, E1
Cohen, MH; Flamm Honig, S; Hirschfeld, S; Ibrahim, A; Johnson, JR; O'Leary, JJ; Pazdur, R; White, RM; Williams, GA1
Arnulfo, A; Baj, G; De Cesaris, MG; Deaglio, S; Ferrero, E; Malavasi, F; Mallone, R; Surico, N; Vigone, A1

Reviews

1 review(s) available for arsenic trioxide and Breast Neoplasms

ArticleYear
p53 as an Effector or Inhibitor of Therapy Response.
    Cold Spring Harbor perspectives in medicine, 2015, Dec-04, Volume: 6, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Breast Neoplasms; Female; Humans; Leukemia, Promyelocytic, Acute; Molecular Targeted Therapy; Oncogene Proteins, Fusion; Oxides; Treatment Outcome; Tretinoin; Tumor Suppressor Protein p53

2015

Trials

1 trial(s) available for arsenic trioxide and Breast Neoplasms

ArticleYear
Combined effect of topical arsenic trioxide and radiation therapy on skin-infiltrating lesions of breast cancer-a pilot study.
    Anti-cancer drugs, 2003, Volume: 14, Issue:10

    Topics: Adult; Aged; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Breast Neoplasms; Combined Modality Therapy; Female; Gels; Humans; Middle Aged; Oxides; Pilot Projects; Skin Neoplasms

2003

Other Studies

42 other study(ies) available for arsenic trioxide and Breast Neoplasms

ArticleYear
Arsenic trioxide and BIBR1532 synergistically inhibit breast cancer cell proliferation through attenuation of NF-κB signaling pathway.
    Life sciences, 2020, Sep-15, Volume: 257

    Topics: Aminobenzoates; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Arsenic Trioxide; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Female; Humans; MCF-7 Cells; Naphthalenes; NF-kappa B; Signal Transduction

2020
Arsenic hexoxide has differential effects on cell proliferation and genome-wide gene expression in human primary mammary epithelial and MCF7 cells.
    Scientific reports, 2021, 02-12, Volume: 11, Issue:1

    Topics: Apoptosis; Arsenic; Arsenic Trioxide; Arsenicals; Breast Neoplasms; Cell Cycle; Cell Cycle Checkpoints; Cell Differentiation; Cell Proliferation; Female; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Mammary Glands, Human; MCF-7 Cells; Primary Cell Culture; Tumor Cells, Cultured

2021
Lipid/PAA-coated mesoporous silica nanoparticles for dual-pH-responsive codelivery of arsenic trioxide/paclitaxel against breast cancer cells.
    Acta pharmacologica Sinica, 2021, Volume: 42, Issue:5

    Topics: Acrylic Resins; Animals; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Breast Neoplasms; Cell Proliferation; Cetrimonium; Drug Carriers; Drug Liberation; Female; G2 Phase Cell Cycle Checkpoints; Human Umbilical Vein Endothelial Cells; Humans; MCF-7 Cells; Mice, Inbred ICR; Nanoparticles; Oligopeptides; Paclitaxel; Porosity; Silicon Dioxide; Xenograft Model Antitumor Assays

2021
Arsenic trioxide inhibits cell growth and motility via up-regulation of let-7a in breast cancer cells.
    Cell cycle (Georgetown, Tex.), 2017, Volume: 16, Issue:24

    Topics: Apoptosis; Arsenic Trioxide; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Humans; MCF-7 Cells; MicroRNAs; Neoplasm Invasiveness; Up-Regulation

2017
Synthesis and characterisation of arsenic nanoparticles and its interaction with DNA and cytotoxic potential on breast cancer cells.
    Chemico-biological interactions, 2018, Nov-01, Volume: 295

    Topics: Antineoplastic Agents; Arsenic Trioxide; Breast Neoplasms; Cell Proliferation; Cells, Cultured; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; HEK293 Cells; Humans; Nanoparticles; Particle Size; Structure-Activity Relationship; Surface Properties

2018
The Osteogenic Niche Is a Calcium Reservoir of Bone Micrometastases and Confers Unexpected Therapeutic Vulnerability.
    Cancer cell, 2018, 11-12, Volume: 34, Issue:5

    Topics: 3T3 Cells; Animals; Antineoplastic Agents; Arsenic Trioxide; Benzamides; Bone Neoplasms; Breast Neoplasms; Calcium; Calcium Signaling; Cell Line, Tumor; Cell Proliferation; Connexin 43; Everolimus; Female; Humans; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; Osteogenesis; Protein Kinase Inhibitors; Pyrazoles; RAW 264.7 Cells; Tumor Microenvironment; U937 Cells

2018
Autocrine human growth hormone increases sensitivity of mammary carcinoma cell to arsenic trioxide-induced apoptosis.
    Molecular and cellular endocrinology, 2013, Sep-05, Volume: 377, Issue:1-2

    Topics: Apoptosis; Arsenic Trioxide; Arsenicals; Autocrine Communication; Breast Neoplasms; Cell Line, Transformed; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Female; Gene Expression Regulation, Neoplastic; Human Growth Hormone; Humans; Matrix Metalloproteinases; MCF-7 Cells; Models, Biological; Neoplasm Metastasis; Oxides; Proteolysis; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; RNA, Messenger; Transcription, Genetic; Tumor Stem Cell Assay; Tumor Suppressor Protein p53

2013
Arsenic trioxide overcomes rapamycin-induced feedback activation of AKT and ERK signaling to enhance the anti-tumor effects in breast cancer.
    PloS one, 2013, Volume: 8, Issue:12

    Topics: Animals; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Feedback, Physiological; Humans; Mice; Oxides; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Sirolimus; Xenograft Model Antitumor Assays

2013
Induction of the mesenchymal to epithelial transition by demethylation- activated microRNA-200c is involved in the anti-migration/invasion effects of arsenic trioxide on human breast cancer cells.
    Molecular carcinogenesis, 2015, Volume: 54, Issue:9

    Topics: Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Breast; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; Methylation; MicroRNAs; Neoplasm Invasiveness; Oxides; Up-Regulation

2015
Galectin-3 as a marker and potential therapeutic target in breast cancer.
    PloS one, 2014, Volume: 9, Issue:9

    Topics: Adult; Apoptosis; Arsenic Trioxide; Arsenicals; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Galectin 3; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Molecular Targeted Therapy; Oxides; RNA, Small Interfering; Survival Analysis

2014
Cotylenin A and arsenic trioxide cooperatively suppress cell proliferation and cell invasion activity in human breast cancer cells.
    International journal of oncology, 2015, Volume: 46, Issue:2

    Topics: Apoptosis; Arsenic Trioxide; Arsenicals; Breast Neoplasms; Cell Cycle; Cell Differentiation; Cell Proliferation; Diterpenes; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Neoplasm Invasiveness; Oxides

2015
Arsenic trioxide inhibits breast cancer cell growth via microRNA-328/hERG pathway in MCF-7 cells.
    Molecular medicine reports, 2015, Volume: 12, Issue:1

    Topics: 3' Untranslated Regions; Adenocarcinoma; Animals; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Binding Sites; Breast Neoplasms; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Female; Gene Expression Regulation, Neoplastic; Genes, Reporter; HEK293 Cells; Humans; Luciferases; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Oxides; Signal Transduction; Xenograft Model Antitumor Assays

2015
Arsenic Trioxide Promotes Paclitaxel Cytotoxicity in Resistant Breast Cancer Cells.
    Asian Pacific journal of cancer prevention : APJCP, 2015, Volume: 16, Issue:13

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Arsenic Trioxide; Arsenicals; Blotting, Western; Breast Neoplasms; Cell Proliferation; Drug Resistance, Neoplasm; Female; Humans; Oxides; Paclitaxel; Phosphoprotein Phosphatases; Protein Phosphatase 2C; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2015
Arsenic trioxide suppresses cell growth and migration via inhibition of miR-27a in breast cancer cells.
    Biochemical and biophysical research communications, 2016, Jan-01, Volume: 469, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Humans; MicroRNAs; Neoplasm Invasiveness; Oxides; Treatment Outcome

2016
Melatonin enhances arsenic trioxide-induced cell death via sustained upregulation of Redd1 expression in breast cancer cells.
    Molecular and cellular endocrinology, 2016, Feb-15, Volume: 422

    Topics: Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Breast Neoplasms; Cell Death; Cell Line, Tumor; Cell Survival; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Humans; MAP Kinase Signaling System; Melatonin; Oxides; Transcription Factors; Up-Regulation

2016
Melatonin promotes ATO-induced apoptosis in MCF-7 cells: Proposing novel therapeutic potential for breast cancer.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 83

    Topics: Apoptosis; Arsenic Trioxide; Arsenicals; Breast Neoplasms; Cell Cycle; Cell Proliferation; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Humans; Inhibitor of Apoptosis Proteins; MCF-7 Cells; Melatonin; Oxides; Proto-Oncogene Proteins c-myc; Real-Time Polymerase Chain Reaction; Survivin; Telomerase; Transcription, Genetic; Tumor Suppressor Protein p53

2016
Stratification and therapeutic potential of PML in metastatic breast cancer.
    Nature communications, 2016, 08-24, Volume: 7

    Topics: Animals; Arsenic Trioxide; Arsenicals; Breast Neoplasms; Cell Line, Tumor; Female; Gene Knockdown Techniques; Humans; MCF-7 Cells; Mice; Neoplasm Invasiveness; Oxides; Promoter Regions, Genetic; Promyelocytic Leukemia Protein; SOX9 Transcription Factor; STAT3 Transcription Factor; Xenograft Model Antitumor Assays

2016
Folate-mediated intracellular drug delivery increases the anticancer efficacy of nanoparticulate formulation of arsenic trioxide.
    Molecular cancer therapeutics, 2009, Volume: 8, Issue:7

    Topics: Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Breast Neoplasms; Drug Carriers; Drug Delivery Systems; Female; Flow Cytometry; Folic Acid; Humans; Liposomes; Nanoparticles; Nasopharyngeal Neoplasms; Oxides; Tumor Cells, Cultured

2009
Essential role of cell cycle regulatory genes p21 and p27 expression in inhibition of breast cancer cells by arsenic trioxide.
    Medical oncology (Northwood, London, England), 2011, Volume: 28, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Separation; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Female; Flow Cytometry; Gene Expression; Genes, cdc; Humans; In Situ Nick-End Labeling; Oligonucleotide Array Sequence Analysis; Oxides; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Transfection

2011
A novel nanoparticulate formulation of arsenic trioxide with enhanced therapeutic efficacy in a murine model of breast cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2010, Jul-15, Volume: 16, Issue:14

    Topics: Animals; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Breast Neoplasms; Cell Proliferation; Cell Survival; Disease Models, Animal; Female; Humans; Mammary Neoplasms, Experimental; Mice; Nanoparticles; Oxides; Rats; Rats, Sprague-Dawley; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2010
Arsenic nanoparticle holds promise in blocking aggressive breast cancer.
    Cancer, 2010, Dec-15, Volume: 116, Issue:24

    Topics: Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Breast Neoplasms; Drug Delivery Systems; Female; Humans; Nanoparticles; Oxides

2010
Arsenic trioxide re-sensitizes ERα-negative breast cancer cells to endocrine therapy by restoring ERα expression in vitro and in vivo.
    Oncology reports, 2011, Volume: 26, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Oxides; Tamoxifen; Transcription, Genetic; Tumor Burden; Xenograft Model Antitumor Assays

2011
JWA enhances As₂O₃-induced tubulin polymerization and apoptosis via p38 in HeLa and MCF-7 cells.
    Apoptosis : an international journal on programmed cell death, 2011, Volume: 16, Issue:11

    Topics: Apoptosis; Arsenic Trioxide; Arsenicals; Breast Neoplasms; Cell Line, Tumor; Female; Flow Cytometry; Gene Silencing; Growth Inhibitors; Heat-Shock Proteins; Humans; Intracellular Signaling Peptides and Proteins; Membrane Transport Proteins; Microscopy, Fluorescence; Oxides; p38 Mitogen-Activated Protein Kinases; Plasmids; Polymerization; RNA, Small Interfering; Signal Transduction; Transfection; Tubulin; Tubulin Modulators; Up-Regulation; Uterine Cervical Neoplasms

2011
Anti-estrogen resistance in breast cancer is induced by the tumor microenvironment and can be overcome by inhibiting mitochondrial function in epithelial cancer cells.
    Cancer biology & therapy, 2011, Nov-15, Volume: 12, Issue:10

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Arsenic Trioxide; Arsenicals; Breast Neoplasms; Cell Line, Tumor; Coculture Techniques; Doxorubicin; Drug Resistance, Neoplasm; Estradiol; Estrogen Receptor Modulators; Female; Fibroblasts; Fulvestrant; Humans; Hypoglycemic Agents; Intracellular Signaling Peptides and Proteins; Ketone Bodies; Lactic Acid; Metformin; Mitochondria; Oxides; Phosphoric Monoester Hydrolases; Poly(ADP-ribose) Polymerase Inhibitors; Tamoxifen; Tumor Microenvironment

2011
Targeting metabolism with arsenic trioxide and dichloroacetate in breast cancer cells.
    Molecular cancer, 2011, Nov-18, Volume: 10

    Topics: Adenosine Triphosphate; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Dichloroacetic Acid; Female; Humans; Membrane Potential, Mitochondrial; Mitochondria; Oxides; Reactive Oxygen Species

2011
Arsenic induces functional re-expression of estrogen receptor α by demethylation of DNA in estrogen receptor-negative human breast cancer.
    PloS one, 2012, Volume: 7, Issue:4

    Topics: Animals; Arsenic Trioxide; Arsenicals; Breast Neoplasms; Cell Line, Tumor; CpG Islands; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Binding Proteins; Drug Screening Assays, Antitumor; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Nude; Neoplasm Proteins; Oxides; Polymerase Chain Reaction; Promoter Regions, Genetic; Protein Binding; RNA, Messenger; Sequence Analysis, DNA

2012
Radiosensitizing effects of arsenic trioxide on MCF-7 human breast cancer cells exposed to 89 strontium chloride.
    Oncology reports, 2012, Volume: 28, Issue:5

    Topics: Apoptosis; Arsenic Trioxide; Arsenicals; bcl-2 Homologous Antagonist-Killer Protein; bcl-X Protein; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Female; Humans; MCF-7 Cells; Oxides; Radiation-Sensitizing Agents; RNA, Messenger; Strontium

2012
Arsenic trioxide inhibits cell growth and induces apoptosis through inactivation of notch signaling pathway in breast cancer.
    International journal of molecular sciences, 2012, Volume: 13, Issue:8

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Blotting, Western; Breast Neoplasms; Cell Movement; Cell Proliferation; Female; Humans; NF-kappa B; Oxides; Real-Time Polymerase Chain Reaction; Receptors, Notch; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Tumor Cells, Cultured

2012
[Effects of arsenic trioxide on the proliferation of human breast cancer SKBR-3 cell and the expression of Notch1].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2012, Volume: 32, Issue:6

    Topics: Arsenic Trioxide; Arsenicals; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Humans; Oxides; Receptor, Notch1; RNA, Messenger; Signal Transduction

2012
Arsenic trioxide-induced growth arrest of breast cancer MCF-7 cells involving FOXO3a and IκB kinase β expression and localization.
    Cancer biotherapy & radiopharmaceuticals, 2012, Volume: 27, Issue:8

    Topics: Apoptosis; Arsenic Trioxide; Arsenicals; Breast Neoplasms; Caspase 3; Cell Growth Processes; Female; Flow Cytometry; Forkhead Box Protein O3; Forkhead Transcription Factors; Growth Inhibitors; Humans; I-kappa B Kinase; Immunohistochemistry; MCF-7 Cells; Oxides; RNA, Messenger; Signal Transduction; Tumor Necrosis Factor-alpha

2012
Comparison of optical and power Doppler ultrasound imaging for non-invasive evaluation of arsenic trioxide as a vascular disrupting agent in tumors.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: Animals; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Blood Vessels; Brain Neoplasms; Breast Neoplasms; Cell Line, Tumor; Female; Humans; Male; Mice; Mice, Nude; Neoplasm Transplantation; Optical Imaging; Oxides; Prostatic Neoplasms; Ultrasonography, Doppler

2012
[Arsenic trioxide restores ERα expression in ERα-negative human breast cancer cells and its treatment efficacy in combination with tamoxifen in xenografts in nude mice].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2012, Volume: 34, Issue:9

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Dose-Response Relationship, Drug; Estrogen Receptor alpha; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Oxides; RNA, Messenger; Tamoxifen; Tumor Burden; Xenograft Model Antitumor Assays

2012
Arsenic trioxide in the mechanism of drug resistance reversal in MCF-7/ADM cell line of human breast cancer.
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2002, Volume: 24, Issue:4

    Topics: Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Breast Neoplasms; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Gene Expression; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Isoenzymes; Oxides; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured

2002
Extramedullary relapse in a patient with acute promyelocytic leukemia: successful treatment with arsenic trioxide, all-trans retinoic acid and gemtuzumab ozogamicin therapies.
    Leukemia research, 2004, Volume: 28, Issue:9

    Topics: Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Breast Neoplasms; Female; Gemtuzumab; Humans; Leukemia, Promyelocytic, Acute; Leukemic Infiltration; Middle Aged; Oxides; Recurrence; Tretinoin

2004
Suppression of cell proliferation and regulation of estrogen receptor alpha signaling pathway by arsenic trioxide on human breast cancer MCF-7 cells.
    The Journal of endocrinology, 2004, Volume: 182, Issue:2

    Topics: Arsenic Trioxide; Arsenicals; Breast Neoplasms; Cell Count; Cell Division; Cell Line, Tumor; Estrogen Receptor alpha; Estrogen Receptor Modulators; Female; Humans; Oxides; Receptors, Estrogen; RNA, Messenger; Signal Transduction

2004
Inhibition of cell proliferation and the action mechanisms of arsenic trioxide (As2O3) on human breast cancer cells.
    Journal of cellular biochemistry, 2004, Sep-01, Volume: 93, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Blotting, Western; Breast Neoplasms; Cell Proliferation; DNA, Neoplasm; Down-Regulation; Female; Flow Cytometry; G1 Phase; Humans; Oxides; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Up-Regulation

2004
Arsenic trioxide causes redistribution of cell cycle, caspase activation, and GADD expression in human colonic, breast, and pancreatic cancer cells.
    Cancer investigation, 2004, Volume: 22, Issue:3

    Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; bcl-2-Associated X Protein; Breast Neoplasms; Caspase 3; Caspases; CCAAT-Enhancer-Binding Proteins; Cell Cycle; Cell Cycle Proteins; Cell Division; Colonic Neoplasms; DNA Fragmentation; Enzyme Activation; Gene Expression Regulation; Genes, bcl-2; Growth Inhibitors; Humans; In Situ Nick-End Labeling; Neoplasm Proteins; Nuclear Proteins; Oxides; Pancreatic Neoplasms; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Transcription Factor CHOP; Transcription Factors; Tumor Cells, Cultured

2004
[Primary research on arsenic trioxide inhibiting human breast cancer cells growth and its mechanisms].
    Zhonghua yi xue za zhi, 2005, May-11, Volume: 85, Issue:17

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Breast Neoplasms; Calcium; Cell Division; Cell Line, Tumor; fas Receptor; Female; Humans; Oxides; Proliferating Cell Nuclear Antigen

2005
Synergistic effect of all-trans-retinoic acid and arsenic trioxide on growth inhibition and apoptosis in human hepatoma, breast cancer, and lung cancer cells in vitro.
    World journal of gastroenterology, 2005, Sep-28, Volume: 11, Issue:36

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Division; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Synergism; Glutathione; Glutathione Transferase; Humans; Lung Neoplasms; Oxides; Tretinoin

2005
Effect of arsenic trioxide on viability, proliferation, and apoptosis in human megakaryocytic leukemia cell lines.
    Experimental hematology, 1999, Volume: 27, Issue:5

    Topics: Apoptosis; Arsenic Trioxide; Arsenicals; Breast Neoplasms; Cell Division; Cell Survival; Gene Expression Regulation, Neoplastic; Genes, bcl-2; HL-60 Cells; Humans; In Situ Nick-End Labeling; Leukemia, Megakaryoblastic, Acute; Oxides; Tumor Cells, Cultured

1999
Drug approval summaries: arsenic trioxide, tamoxifen citrate, anastrazole, paclitaxel, bexarotene.
    The oncologist, 2001, Volume: 6, Issue:1

    Topics: Anastrozole; Anticarcinogenic Agents; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; Arsenic Trioxide; Arsenicals; Bexarotene; Breast Neoplasms; Drug Approval; Female; Humans; Leukemia, Promyelocytic, Acute; Lymphoma, T-Cell, Cutaneous; Nitriles; Oxides; Paclitaxel; Tamoxifen; Tetrahydronaphthalenes; Triazoles; United States; United States Food and Drug Administration

2001
Arsenic trioxide and breast cancer: analysis of the apoptotic, differentiative and immunomodulatory effects.
    Breast cancer research and treatment, 2002, Volume: 73, Issue:1

    Topics: Adjuvants, Immunologic; Apoptosis; Arsenic Trioxide; Arsenicals; Blotting, Western; Breast Neoplasms; Cell Differentiation; Cell Division; Drug Resistance, Neoplasm; Flow Cytometry; Fluorescent Antibody Technique; Genes, bcl-2; Glutathione; Humans; In Vitro Techniques; Intercellular Adhesion Molecule-1; Killer Cells, Lymphokine-Activated; Lymphocyte Function-Associated Antigen-1; Oxides; Sulfhydryl Compounds; Tumor Cells, Cultured

2002