Compounds > arsenic trioxide
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arsenic trioxide and Astrocytoma, Grade IV

arsenic trioxide has been researched along with Astrocytoma, Grade IV in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (14.29)29.6817
2010's23 (82.14)24.3611
2020's1 (3.57)2.80

Authors

AuthorsStudies
Defant, A; Mancini, I; Pancher, M; Quattrone, A; Rosatti, EF; Sidarovich, V; Sighel, D; Vigna, J1
Appel, D; Gülden, M; Seibert, H; Syska, M; Uecker, S; Wages, F1
Ahmadian, S; Alimoghaddam, K; Ghaffari, SH; Ghavamzadeh, A; Mesbahi, Y; Zekri, A1
Bureta, C; Komiya, S; Maeda, S; Nagano, S; Saitoh, Y; Sasaki, H; Setoguchi, T; Taniguchi, N; Tokumoto, H1
Agarwal, N; Bloom, L; Bregy, A; Gersey, Z; Komotar, RJ; Osiason, AD; Shah, S; Thompson, JW1
Assuncao, A; Cavenee, WK; Cloughesy, TF; Dang, J; Furnari, FB; Gini, B; Iwanami, A; Kitabayashi, I; Kohyama, J; Matsutani, T; Mischel, PS; Nael, A; Nakamura, M; Okano, H; Toyama, Y; Yang, H; Zanca, C; Zhu, S1
Bi, Y; Chen, X; Han, D; Ji, Z; Li, H; Liu, H; Liu, Y; Shen, C; Shi, C; Wang, C; Wu, J; Yang, G; Zhang, D; Zhao, S1
Cavenee, WK; Cloughesy, TF; Iwanami, A; Mischel, PS1
Bjerkvig, R; Huszthy, PC; Lah Turnšek, T; Motaln, H; Primon, M; Talasila, KM; Torkar, A1
Albert, L; Jhanwar-Uniyal, M; Karsy, M; Murali, R1
Ding, D; Eberhart, CG; Lim, KS1
Gwak, HS; Jin, HO; Jung, HW; Park, IC; Park, MJ; Rhee, CH; Woo, SH1
Bi, Y; Chen, X; Cho, K; Hou, X; Li, C; Liu, H; Liu, Y; Peng, F; Shen, C; Wang, K; Wang, X; Yang, Z; Zhang, J; Zhang, W; Zhang, X; Zhao, S; Zheng, Z; Zhong, C; Zou, H1
Fukami, T; Fukuda, M; Hojo, M; Inubushi, T; Miyamoto, S; Muraki, K; Nozaki, K; Onishi, N; Saiki, M; Satow, T; Saya, H; Shiino, A; Tanigaki, K; Yamada, S; Yoshimura, Y1
Alimoghaddam, K; Ghaffari, SH; Ghavamzadeh, A; Hosseini, E; Shidfar, F; Tavoosidana, G1
Bao, S; Bian, XW; Cheng, L; Chu, CW; Fang, X; Huang, Z; Ke, SQ; Rich, JN; Shi, Y; Xie, Q; Zhou, W1
Alimoghaddam, K; Bashash, D; Dizaji, MZ; Ghaffari, SH; Ghavamzadeh, A; Momeny, M; Yousefi, M; Zekri, A1
Kawamoto, K; Li, Q; Li, Y; Zhao, S; Zhen, Y1
Castino, R; Falnoga, I; Isidoro, C; Lah, TT; Mirković, B; Pucer, A; Slejkovec, Z1
Crocker, IR; Curran, WJ; McDonald, MW; Shu, HK1
Battastini, AM; Braganhol, E; Dalmolin, RJ; de Souza, LH; Gelain, DP; Moreira, JC; Pasquali, MA; Schröder, R; Zanotto-Filho, A1
Sun, H; Zhang, S1
Alimoghaddam, K; Dizaji, MZ; Ghaffari, SH; Ghavamzadeh, A; Malehmir, M1
Falnoga, I; Marc, J; Mlakar, SJ; Šlejkovec, Z; Zajc, I; Zelenik Pevec, A; Žnidarič, MT1
Knox, SJ; Ning, S1
Fujita, N; Haga, N; Tsuruo, T1
Aldape, K; Aoki, H; Bogler, O; Conrad, C; Hess, K; Hollingsworth, EF; Iwado, E; Kobayashi, R; Kondo, S; Kondo, Y; Mills, G; Sawaya, R; Shingu, T; Shinojima, N; Tamada, Y; Yamamoto, A; Yokoyama, T; Zhang, L1
Kawakami, K; Kawamoto, K; Shi, C; Tsuchida, T; Zhao, S1

Reviews

1 review(s) available for arsenic trioxide and Astrocytoma, Grade IV

ArticleYear
Therapeutic Targeting of the Notch Pathway in Glioblastoma Multiforme.
    World neurosurgery, 2019, Volume: 131

    Topics: ADAM Proteins; Amyloid Precursor Protein Secretases; Antineoplastic Agents; Arsenic Trioxide; Brain Neoplasms; Cell Hypoxia; Cell Line, Tumor; Gene Knockdown Techniques; Glioblastoma; Humans; Inhibitor of Differentiation Proteins; Kruppel-Like Transcription Factors; MicroRNAs; Microvessels; Molecular Targeted Therapy; Neoplasm Proteins; Netrin-1; Niclosamide; Receptors, Notch; Receptors, Urokinase Plasminogen Activator; Resveratrol; Signal Transduction; Tretinoin

2019

Trials

1 trial(s) available for arsenic trioxide and Astrocytoma, Grade IV

ArticleYear
PML mediates glioblastoma resistance to mammalian target of rapamycin (mTOR)-targeted therapies.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Mar-12, Volume: 110, Issue:11

    Topics: Animals; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Drug Resistance, Neoplasm; ErbB Receptors; Female; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Male; Mice; Nuclear Proteins; Oxides; Promyelocytic Leukemia Protein; Signal Transduction; TOR Serine-Threonine Kinases; Transcription Factors; Tumor Suppressor Proteins

2013

Other Studies

26 other study(ies) available for arsenic trioxide and Astrocytoma, Grade IV

ArticleYear
Expanding the Chemical Space of Arsenicin A-C Related Polyarsenicals and Evaluation of Some Analogs as Inhibitors of Glioblastoma Stem Cell Growth.
    Marine drugs, 2023, Mar-17, Volume: 21, Issue:3

    Topics: Adamantane; Arsenic Trioxide; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Stem Cells

2023
Chrysin and silibinin sensitize human glioblastoma cells for arsenic trioxide.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2017, Volume: 105

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; ATP-Binding Cassette Transporters; Cell Line, Tumor; Flavonoids; Glioblastoma; Humans; Oxides; Silybin; Silymarin

2017
Targeting of EGFR increase anti-cancer effects of arsenic trioxide: Promising treatment for glioblastoma multiform.
    European journal of pharmacology, 2018, Feb-05, Volume: 820

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Synergism; ErbB Receptors; Erlotinib Hydrochloride; G2 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; M Phase Cell Cycle Checkpoints; Molecular Targeted Therapy; Oxides; Reactive Oxygen Species

2018
Synergistic effect of arsenic trioxide, vismodegib and temozolomide on glioblastoma.
    Oncology reports, 2019, Volume: 41, Issue:6

    Topics: Anilides; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Arsenic Trioxide; Caspase 3; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Mice; Neoplasm Recurrence, Local; Pyridines; Signal Transduction; Temozolomide; Xenograft Model Antitumor Assays

2019
Arsenic trioxide depletes cancer stem-like cells and inhibits repopulation of neurosphere derived from glioblastoma by downregulation of Notch pathway.
    Toxicology letters, 2013, Jun-20, Volume: 220, Issue:1

    Topics: Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Basic Helix-Loop-Helix Transcription Factors; Brain Neoplasms; Cell Line; Cell Proliferation; Gene Expression Regulation, Neoplastic; Glioblastoma; Homeodomain Proteins; Humans; Neoplastic Stem Cells; Oxides; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptors, Notch; Signal Transduction; STAT3 Transcription Factor; Transcription Factor HES-1

2013
Arsenic reverses glioblastoma resistance to mTOR-targeted therapies.
    Cell cycle (Georgetown, Tex.), 2013, May-15, Volume: 12, Issue:10

    Topics: Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Brain Neoplasms; Drug Resistance, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Glioblastoma; Humans; Leukemia, Promyelocytic, Acute; Oxides; Quinazolines; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases

2013
Cathepsin L silencing enhances arsenic trioxide mediated in vitro cytotoxicity and apoptosis in glioblastoma U87MG spheroids.
    Experimental cell research, 2013, Oct-15, Volume: 319, Issue:17

    Topics: Apoptosis; Arsenic Trioxide; Arsenicals; Brain Neoplasms; Cathepsin L; Cell Line, Tumor; Cell Survival; Gene Silencing; Glioblastoma; Humans; Oxides; Spheroids, Cellular; Tumor Cells, Cultured

2013
The impact of arsenic trioxide and all-trans retinoic acid on p53 R273H-codon mutant glioblastoma.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2014, Volume: 35, Issue:5

    Topics: Amino Acid Sequence; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Codon; Extracellular Signal-Regulated MAP Kinases; Genes, p53; Glioblastoma; Humans; Molecular Sequence Data; Mutation; Neoplastic Stem Cells; Oxides; Tretinoin

2014
Arsenic trioxide inhibits Hedgehog, Notch and stem cell properties in glioblastoma neurospheres.
    Acta neuropathologica communications, 2014, Mar-31, Volume: 2

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Cycle; Cell Growth Processes; Cell Line, Tumor; Cell Proliferation; Colony-Forming Units Assay; Dose-Response Relationship, Drug; Flow Cytometry; Gene Expression Regulation, Neoplastic; Glial Fibrillary Acidic Protein; Glioblastoma; Hedgehog Proteins; Humans; Neoplastic Stem Cells; Oxides; Receptors, Notch; Signal Transduction

2014
Tetraarsenic oxide-induced inhibition of malignant glioma cell invasion in vitro via a decrease in matrix metalloproteinase secretion and protein kinase B phosphorylation.
    Journal of neurosurgery, 2014, Volume: 121, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Chromones; Enzyme Activation; Enzyme Inhibitors; Glioblastoma; Humans; Matrix Metalloproteinase 14; Matrix Metalloproteinase 2; Morpholines; Neoplasm Invasiveness; Oxides; Phosphorylation; Proto-Oncogene Proteins c-akt

2014
Impact of autophagy inhibition at different stages on cytotoxic effect of autophagy inducer in glioblastoma cells.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2015, Volume: 35, Issue:4

    Topics: Adenine; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Arsenic Trioxide; Arsenicals; Autophagy; Beclin-1; Blotting, Western; Brain Neoplasms; Caspase 3; Cell Line, Tumor; Chloroquine; Drug Synergism; Flow Cytometry; Glioblastoma; Humans; Membrane Proteins; Microscopy, Electron, Transmission; Oxides; rab GTP-Binding Proteins; rab7 GTP-Binding Proteins; RNA Interference; RNA, Small Interfering

2015
Arsenic trioxide sensitizes glioblastoma to a myc inhibitor.
    PloS one, 2015, Volume: 10, Issue:6

    Topics: Aged; Animals; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Brain Neoplasms; Cell Differentiation; Cell Proliferation; Disease Progression; ErbB Receptors; Female; Glioblastoma; Hedgehog Proteins; Humans; Magnetic Resonance Imaging; Male; Mice, SCID; Middle Aged; Neoplastic Stem Cells; Oxides; Proto-Oncogene Proteins c-myc; Signal Transduction; Thiazoles; Xenograft Model Antitumor Assays

2015
Arsenic trioxide Alters the MicroRNA Expression Profile of U87 glioblastoma.
    Anti-cancer agents in medicinal chemistry, 2015, Volume: 16, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Gene Expression Profiling; Glioblastoma; Humans; MicroRNAs; Oxides; Real-Time Polymerase Chain Reaction; Structure-Activity Relationship

2015
Arsenic trioxide disrupts glioma stem cells via promoting PML degradation to inhibit tumor growth.
    Oncotarget, 2015, Nov-10, Volume: 6, Issue:35

    Topics: Animals; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Brain Neoplasms; Cell Proliferation; Female; Glioblastoma; Humans; Mice, Inbred C57BL; Mice, Nude; Neoplastic Stem Cells; Nuclear Proteins; Oxides; Promyelocytic Leukemia Protein; Proteolysis; Proto-Oncogene Proteins c-myc; RNA Interference; Signal Transduction; Spheroids, Cellular; Time Factors; Transcription Factors; Transfection; Tumor Burden; Tumor Cells, Cultured; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays

2015
Arsenic Trioxide Induces Apoptosis and Incapacitates Proliferation and Invasive Properties of U87MG Glioblastoma Cells through a Possible NF-κB-Mediated Mechanism.
    Asian Pacific journal of cancer prevention : APJCP, 2016, Volume: 17, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Blotting, Western; Cell Adhesion; Cell Movement; Cell Proliferation; Glioblastoma; Humans; Neoplasm Invasiveness; NF-kappa B; Oxides; Phosphorylation; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Telomerase; Tumor Cells, Cultured

2016
Arsenic trioxide-mediated Notch pathway inhibition depletes the cancer stem-like cell population in gliomas.
    Cancer letters, 2010, Jun-01, Volume: 292, Issue:1

    Topics: Animals; Arsenic Trioxide; Arsenicals; Brain Neoplasms; Cell Line, Tumor; Down-Regulation; Glioblastoma; Humans; Intermediate Filament Proteins; Male; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplastic Stem Cells; Nerve Tissue Proteins; Nestin; Oxides; Receptors, Notch; Signal Transduction

2010
Differential role of cathepsins B and L in autophagy-associated cell death induced by arsenic trioxide in U87 human glioblastoma cells.
    Biological chemistry, 2010, Volume: 391, Issue:5

    Topics: Adenine; Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Autophagy; Caspases; Cathepsin B; Cathepsin L; Cell Line, Tumor; Dipeptides; Down-Regulation; Epoxy Compounds; Glioblastoma; Humans; Macrolides; Oxides; Pyridines

2010
Pattern of failure after limited margin radiotherapy and temozolomide for glioblastoma.
    International journal of radiation oncology, biology, physics, 2011, Jan-01, Volume: 79, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease Progression; Disease-Free Survival; Dose Fractionation, Radiation; Female; Follow-Up Studies; Glioblastoma; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Oxides; Radiotherapy Planning, Computer-Assisted; Temozolomide; Tomography, X-Ray Computed; Treatment Failure; Tumor Burden; Young Adult

2011
NFκB inhibitors induce cell death in glioblastomas.
    Biochemical pharmacology, 2011, Feb-01, Volume: 81, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Astrocytes; Brain Neoplasms; Cell Cycle; Cell Death; Cell Line, Tumor; Cisplatin; Curcumin; Doxorubicin; Drug Synergism; Glioblastoma; Humans; Leupeptins; Molecular Targeted Therapy; NF-kappa B; Nitriles; Oxides; Rats; Sesquiterpenes; Signal Transduction; Sulfones

2011
Arsenic trioxide regulates the apoptosis of glioma cell and glioma stem cell via down-regulation of stem cell marker Sox2.
    Biochemical and biophysical research communications, 2011, Jul-08, Volume: 410, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Biomarkers; Brain Neoplasms; Cell Line, Tumor; Down-Regulation; Glioblastoma; Humans; Neoplastic Stem Cells; Oxides; SOXB1 Transcription Factors; Transcription, Genetic

2011
Synergistic effects of arsenic trioxide and silibinin on apoptosis and invasion in human glioblastoma U87MG cell line.
    Neurochemical research, 2012, Volume: 37, Issue:2

    Topics: Apoptosis; Arsenic Trioxide; Arsenicals; Brain Neoplasms; Cell Line, Tumor; Drug Synergism; Glioblastoma; Humans; Neoplasm Invasiveness; Oxides; Silybin; Silymarin

2012
Arsenic trioxide (ATO) influences the gene expression of metallothioneins in human glioblastoma cells.
    Biological trace element research, 2012, Volume: 149, Issue:3

    Topics: Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Gene Expression; Glioblastoma; Humans; Metallothionein; Oxides

2012
Increased cure rate of glioblastoma using concurrent therapy with radiotherapy and arsenic trioxide.
    International journal of radiation oncology, biology, physics, 2004, Sep-01, Volume: 60, Issue:1

    Topics: Animals; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Brain Neoplasms; Cell Line, Tumor; Combined Modality Therapy; Glioblastoma; Humans; Mice; Mice, Nude; Oxides; Reactive Oxygen Species; Transplantation, Heterologous; Tumor Stem Cell Assay

2004
Involvement of mitochondrial aggregation in arsenic trioxide (As2O3)-induced apoptosis in human glioblastoma cells.
    Cancer science, 2005, Volume: 96, Issue:11

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; bcl-2-Associated X Protein; Brain Neoplasms; Caspases; Enzyme Activation; Glioblastoma; Humans; Membrane Potentials; Mitochondria; Oxides; Reactive Oxygen Species; Tumor Cells, Cultured

2005
Monitoring autophagy in glioblastoma with antibody against isoform B of human microtubule-associated protein 1 light chain 3.
    Autophagy, 2008, Volume: 4, Issue:4

    Topics: Animals; Antibodies; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Autophagy; Cell Line, Tumor; Ceramides; Dacarbazine; Female; Glioblastoma; Humans; Mice; Mice, Nude; Microtubule-Associated Proteins; Neoplasm Transplantation; Oligonucleotide Array Sequence Analysis; Oxides; Paclitaxel; Phagosomes; Survival Rate; Temozolomide; Transplantation, Heterologous; Tubulin Modulators

2008
Effect of As2O3 on cell cycle progression and cyclins D1 and B1 expression in two glioblastoma cell lines differing in p53 status.
    International journal of oncology, 2002, Volume: 21, Issue:1

    Topics: Arsenic Trioxide; Arsenicals; Blotting, Western; Brain Neoplasms; Cell Cycle; Cell Division; Cyclin B; Cyclin B1; Cyclin D1; Dose-Response Relationship, Drug; Flow Cytometry; Glioblastoma; Humans; Oxides; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2002