Page last updated: 2024-08-26

arsenic and Long QT Syndrome

arsenic has been researched along with Long QT Syndrome in 22 studies

Research

Studies (22)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	9 (40.91)	29.6817
2010's	12 (54.55)	24.3611
2020's	1 (4.55)	2.80

Authors

Authors	Studies
Li, D; Que, Y; Sun, Y; Wang, L; Yang, X; Zhu, H	1
Feng, L; Li, B; Li, F; Liu, Y; Shi, Y; Wang, J; Yan, M	1
Bai, Y; Chai, L; Chu, Q; Du, W; Jiang, Y; Li, A; Li, G; Li, Y; Pavlov, V; Qin, Y; Sun, X; Tuguzbaeva, G; Wang, H; Wang, Z; Yang, B; Yue, E	1
Hai, Y; Li, H; Li, J; Li, Y; Song, P; Wang, X; Xie, Q; Zhao, L	1
Ando, H; Fujimura, A; Kakei, M; Koshimizu, TA; Kumazaki, M; Taniguchi, Y; Ushijima, K; Washino, S; Yamato, S; Yoshida, M	1
Cifuentes, F; Nwokocha, CR; Palacios, J	1
Amarasiriwardena, C; Baccarelli, A; Baja, E; Mordukhovich, I; Schwartz, J; Sparrow, D; Suh, H; Vokonas, P; Wright, RO	1
Chhabra, S; Kaufman, KR; Levitt, M; Sood, R	1
Dennis, AT; Ficker, E; Heredia-Moya, J; Kirk, KL; Obejero-Paz, C; Overholt, JL; Wan, X	1
Cai, F; Chu, W; Dong, D; Du, Z; Li, B; Li, C; Liang, H; Lu, Y; Qiao, G; Qu, X; Wang, X; Yang, B; Yu, X; Zhang, Y; Zhao, D; Zhao, X	1
Cai, B; Chen, X; Du, Z; Fan, Y; Liang, H; Lu, Y; Shan, H; Song, X; Xu, C; Yang, B; Yang, L; Zhang, Y	1
Du, Z; Fan, Y; Hang, P; Liu, Y; Pan, Z; Wang, C; Wang, N; Zhang, Y	1
Barbey, JT; Pezzullo, JC; Soignet, SL	1
Drolet, B; Roden, DM; Simard, C	1
Bai, YL; Chu, WF; Dong, DL; Liu, Y; Sun, HL; Wang, XH; Yang, BF; Zhou, J	1
Hayashi, H; Katoh, H; Naito, K; Ohnishi, K; Satoh, H; Takeshita, A; Terada, H; Uehara, A; Yamazaki, K	1
Antonioli, E; Cas, LD; D'Aloia, A; Raddino, R; Vizzardi, E; Zanini, G	1
Fujisawa, S; Fujita, Y; Matsui, H; Naito, K; Nakamura, S; Ohnishi, K; Ohno, R; Satoh, H; Shigeno, K; Shinjo, K; Sugiyama, S; Takeshita, A; Terada, H; Yoshida, H	1
Barbey, JT	1
Singer, JW	1
Castagné, V; Goineau, S	1
Beumer, JH; Edelman, MJ; Feliciano, J; Gobbru, J; Lapidus, R; Liu, T; Styblo, M	1

Reviews

1 review(s) available for arsenic and Long QT Syndrome

Article	Year
Cardiac toxicity of arsenic trioxide. Blood, 2001, Sep-01, Volume: 98, Issue:5 Topics: Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Artifacts; Electrocardiography; Electrolytes; Humans; Leukemia; Long QT Syndrome; Oxides; Torsades de Pointes	2001

Trials

2 trial(s) available for arsenic and Long QT Syndrome

Article	Year
Arrhythmogenic effects of arsenic trioxide in patients with acute promyelocytic leukemia and an electrophysiological study in isolated guinea pig papillary muscles. Circulation journal : official journal of the Japanese Circulation Society, 2006, Volume: 70, Issue:11 Topics: Action Potentials; Animals; Antineoplastic Agents; Antioxidants; Arrhythmias, Cardiac; Arsenic Trioxide; Arsenicals; Butylated Hydroxytoluene; Electrocardiography; Electrophysiology; Guinea Pigs; Humans; Leukemia, Promyelocytic, Acute; Lipid Peroxidation; Long QT Syndrome; Myocardial Contraction; Oxides; Papillary Muscles; Poisons; Reactive Oxygen Species; Tetrodotoxin	2006
Phase I and pharmacokinetic evaluation of the anti-telomerase agent KML-001 with cisplatin in advanced solid tumors. Cancer chemotherapy and pharmacology, 2016, Volume: 78, Issue:5 Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arsenic; Arsenites; Cisplatin; Endpoint Determination; Enzyme Inhibitors; Female; Humans; Long QT Syndrome; Male; Middle Aged; Neoplasms; Platinum; Sodium Compounds; Telomerase; Treatment Outcome	2016

Article

Year

Arrhythmogenic effects of arsenic trioxide in patients with acute promyelocytic leukemia and an electrophysiological study in isolated guinea pig papillary muscles.

Circulation journal : official journal of the Japanese Circulation Society, 2006, Volume: 70, Issue:11

Topics: Action Potentials; Animals; Antineoplastic Agents; Antioxidants; Arrhythmias, Cardiac; Arsenic Trioxide; Arsenicals; Butylated Hydroxytoluene; Electrocardiography; Electrophysiology; Guinea Pigs; Humans; Leukemia, Promyelocytic, Acute; Lipid Peroxidation; Long QT Syndrome; Myocardial Contraction; Oxides; Papillary Muscles; Poisons; Reactive Oxygen Species; Tetrodotoxin

2006

Phase I and pharmacokinetic evaluation of the anti-telomerase agent KML-001 with cisplatin in advanced solid tumors.

Cancer chemotherapy and pharmacology, 2016, Volume: 78, Issue:5

Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arsenic; Arsenites; Cisplatin; Endpoint Determination; Enzyme Inhibitors; Female; Humans; Long QT Syndrome; Male; Middle Aged; Neoplasms; Platinum; Sodium Compounds; Telomerase; Treatment Outcome

2016

Other Studies

19 other study(ies) available for arsenic and Long QT Syndrome

Article	Year
Ventricular repolarization dynamics in arsenic trioxide treatment of acute promyelocytic leukemia. International journal of cardiology, 2020, 05-01, Volume: 306 Topics: Arsenic Trioxide; Arsenicals; Electrocardiography; Heart Rate; Humans; Leukemia, Promyelocytic, Acute; Long QT Syndrome; Oxides	2020
Mechanism of As2O3-Induced Action Potential Prolongation and Using hiPS-CMs to Evaluate the Rescue Efficacy of Drugs With Different Rescue Mechanism. Toxicological sciences : an official journal of the Society of Toxicology, 2017, 08-01, Volume: 158, Issue:2 Topics: Action Potentials; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; ERG1 Potassium Channel; HEK293 Cells; Humans; Induced Pluripotent Stem Cells; Leukemia, Promyelocytic, Acute; Long QT Syndrome; Lysosomes; Myocytes, Cardiac; Oxides; Patch-Clamp Techniques; Proteolysis; Resveratrol; Stilbenes; Terfenadine	2017
Downregulation of Long Non-Coding RNA Kcnq1ot1: An Important Mechanism of Arsenic Trioxide-Induced Long QT Syndrome. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 45, Issue:1 Topics: Action Potentials; Animals; Arsenic Trioxide; Arsenicals; Cells, Cultured; Down-Regulation; KCNQ1 Potassium Channel; Lentivirus; Long QT Syndrome; Mice; Myocytes, Cardiac; Oxides; Patch-Clamp Techniques; Phenotype; RNA Interference; RNA, Long Noncoding; RNA, Small Interfering	2018
Realgar transforming solution as a novel arsenic agent with a lower risk of cardiotoxicity. Journal of pharmacological sciences, 2019, Volume: 140, Issue:2 Topics: Animals; Arsenicals; Cardiotoxicity; Cell Proliferation; Cells, Cultured; Female; Humans; Leukemia; Long QT Syndrome; Male; Mice; Rats, Wistar; Risk; Solutions; Sulfides	2019
α-Lipoic acid protects against arsenic trioxide-induced acute QT prolongation in anesthetized guinea pigs. European journal of pharmacology, 2013, Apr-05, Volume: 705, Issue:1-3 Topics: Anesthesia; Animals; Arsenic Trioxide; Arsenicals; Cardiotonic Agents; Delayed Rectifier Potassium Channels; Guinea Pigs; Long QT Syndrome; Male; Myocytes, Cardiac; Oxides; Thioctic Acid	2013
Synchronization in the Heart Rate and the Vasomotion in Rat Aorta: Effect of Arsenic Trioxide. Cardiovascular toxicology, 2016, Volume: 16, Issue:1 Topics: Acetylcholine; Anesthesia; Animals; Antineoplastic Agents; Aorta; Arsenic Trioxide; Arsenicals; Electrocardiography; Female; Heart Rate; In Vitro Techniques; Isometric Contraction; Long QT Syndrome; Male; Nitric Oxide Donors; Nitroprusside; Oxides; Potassium Channels; Rats; Rats, Sprague-Dawley; Vasodilator Agents	2016
Association between low-level environmental arsenic exposure and QT interval duration in a general population study. American journal of epidemiology, 2009, Sep-15, Volume: 170, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Arrhythmias, Cardiac; Arsenic; Arsenicals; Calcium Channel Blockers; Confidence Intervals; Cross-Sectional Studies; Death, Sudden, Cardiac; Dose-Response Relationship, Drug; Environmental Exposure; Humans; Long QT Syndrome; Male; Middle Aged; Nails; Regression Analysis; Risk Factors; Surveys and Questionnaires; United States	2009
Arsenic trioxide and olanzapine co-administration: case analysis. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2011, Volume: 17, Issue:3 Topics: Adult; Antineoplastic Agents; Antipsychotic Agents; Arsenic Trioxide; Arsenicals; Benzodiazepines; Drug Administration Schedule; Drug Interactions; Drug Monitoring; Electrocardiography; Humans; Leukemia, Promyelocytic, Acute; Long QT Syndrome; Male; Mental Disorders; Olanzapine; Oxides; Patient Safety; Risk Factors	2011
Oxidative inactivation of the lipid phosphatase phosphatase and tensin homolog on chromosome ten (PTEN) as a novel mechanism of acquired long QT syndrome. The Journal of biological chemistry, 2011, Jan-28, Volume: 286, Issue:4 Topics: Animals; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Calcium; Cells, Cultured; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; Heart Ventricles; Humans; Long QT Syndrome; Myocytes, Cardiac; Oxidation-Reduction; Oxides; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Phosphates; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Signal Transduction	2011
Arsenic-induced interstitial myocardial fibrosis reveals a new insight into drug-induced long QT syndrome. Cardiovascular research, 2012, Oct-01, Volume: 96, Issue:1 Topics: Animals; Animals, Newborn; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Collagen; Down-Regulation; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Fibroblasts; Fibrosis; Guinea Pigs; HEK293 Cells; Humans; Long QT Syndrome; Myocardium; Myocytes, Cardiac; Oxides; Potassium Channels, Inwardly Rectifying; Rats; Rats, Wistar; Signal Transduction; Transforming Growth Factor beta1	2012
Upregulation of microRNA-1 and microRNA-133 contributes to arsenic-induced cardiac electrical remodeling. International journal of cardiology, 2013, Sep-10, Volume: 167, Issue:6 Topics: Animals; Arsenic Trioxide; Arsenicals; Atrial Remodeling; Cells, Cultured; Guinea Pigs; Long QT Syndrome; Male; MicroRNAs; Myocytes, Cardiac; Oxides; Up-Regulation	2013
Genistein ameliorates adverse cardiac effects induced by arsenic trioxide through preventing cardiomyocytes apoptosis. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2013, Volume: 31, Issue:1 Topics: Animals; Anticarcinogenic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Calcium; Calcium Channels, L-Type; Caspase 3; Cells, Cultured; Down-Regulation; Electrocardiography; Genistein; Hemodynamics; JNK Mitogen-Activated Protein Kinases; Long QT Syndrome; Male; Membrane Potential, Mitochondrial; Myocytes, Cardiac; Oxides; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats; Rats, Wistar	2013
Effect of arsenic trioxide on QT interval in patients with advanced malignancies. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Oct-01, Volume: 21, Issue:19 Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Child; Child, Preschool; Clinical Trials as Topic; Electrocardiography; Female; Humans; Leukemia, Promyelocytic, Acute; Long QT Syndrome; Male; Middle Aged; Neoplasms; Oxides; Retrospective Studies; Torsades de Pointes	2003
Unusual effects of a QT-prolonging drug, arsenic trioxide, on cardiac potassium currents. Circulation, 2004, Jan-06, Volume: 109, Issue:1 Topics: Animals; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; CHO Cells; Cricetinae; Cricetulus; Glyburide; Heart; Long QT Syndrome; Myocardium; Oxides; Pinacidil; Potassium Channels; Potassium Channels, Inwardly Rectifying; Potassium Channels, Voltage-Gated	2004
Choline-modulated arsenic trioxide-induced prolongation of cardiac repolarization in Guinea pig. Basic & clinical pharmacology & toxicology, 2006, Volume: 98, Issue:4 Topics: Animals; Arsenic Trioxide; Arsenicals; Calcium; Choline; Electrocardiography; Female; Guinea Pigs; Heart; In Vitro Techniques; Long QT Syndrome; Male; Myocytes, Cardiac; Oxides; Patch-Clamp Techniques	2006
QT prolongation: a case of arsenical pericardial and pleural effusion. Cardiovascular toxicology, 2008, Volume: 8, Issue:1 Topics: Aged; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Humans; Leukemia, Promyelocytic, Acute; Long QT Syndrome; Male; Oxides; Pericardial Effusion; Pleural Effusion; Recovery of Function; Withholding Treatment	2008
Prolongation of the QT interval and ventricular tachycardia in patients treated with arsenic trioxide for acute promyelocytic leukemia. Annals of internal medicine, 2000, Dec-05, Volume: 133, Issue:11 Topics: Adult; Aged; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Electrocardiography, Ambulatory; Female; Humans; Leukemia, Promyelocytic, Acute; Long QT Syndrome; Male; Middle Aged; Oxides; Prospective Studies; Recurrence; Remission Induction; Tachycardia, Ventricular	2000
Cardiac toxicity of arsenic trioxide. Blood, 2001, Sep-01, Volume: 98, Issue:5 Topics: Adverse Drug Reaction Reporting Systems; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Drug Approval; Drug Industry; Drug Labeling; Electrocardiography; Electrolytes; Humans; Leukemia; Long QT Syndrome; Oxides; Practice Guidelines as Topic; Safety; Torsades de Pointes; United States; United States Food and Drug Administration	2001
Proarrhythmic risk assessment using conventional and new in vitro assays. Regulatory toxicology and pharmacology : RTP, 2017, Volume: 88 Topics: Action Potentials; Anti-Arrhythmia Agents; Arsenic; Dose-Response Relationship, Drug; Drug Discovery; Drug Evaluation, Preclinical; Fluoroquinolones; Humans; In Vitro Techniques; Induced Pluripotent Stem Cells; Long QT Syndrome; Moxifloxacin; Myocytes, Cardiac; Pentamidine; Phenethylamines; Risk Assessment; Sulfonamides	2017