Page last updated: 2024-08-26

arsenic and Leucocythaemia

arsenic has been researched along with Leucocythaemia in 133 studies

Research

Studies (133)

TimeframeStudies, this research(%)All Research%
pre-199022 (16.54)18.7374
1990's9 (6.77)18.2507
2000's61 (45.86)29.6817
2010's34 (25.56)24.3611
2020's7 (5.26)2.80

Authors

AuthorsStudies
Fang, J; Shi, D; Song, ZL; Xu, Q; Yao, X; Zhang, J1
Manley, PW1
Gao, LX; Liu, TT; Liu, Y; Liu, YJ; She, WY; Shi, XM1
Bai, Y; Guo, Q; Liu, W; Wang, L1
Chen, S; Lv, X; Yu, J; Zhang, L1
Watts, G1
Hai, Y; Li, H; Li, J; Li, Y; Song, P; Wang, X; Xie, Q; Zhao, L1
Feng, L; Jiang, W; Li, Y; Shan, N; Wang, X1
Wang, YS; Wei, HL; Zhou, ST1
Cui, J; Lin, S; Yang, H1
Cai, D; Dong, WW; Gao, F; Liu, J; Sun, K; Wang, W; Wang, Y; Zheng, Z1
Liu, Y; Ren, X; Wang, D; Yu, R; Zeng, L1
Diamantidis, MD; Papaioannou, M1
Benbijja, M; Bobé, P; Mellouk, A1
Inomata, T; Sunami, K1
Kong, P; Ma, Y; Shen, Z; Yang, S; Zeng, D; Zhang, X; Zou, Z1
Li, Y; Liu, J; Ma, X; Ye, BC; Zhang, B; Zuo, P1
Fan, J; Guo, K; Li, Y; Li, Z; Weng, G; Wu, J; Xia, P; Zeng, Y; Zheng, R1
Ai, Z; Chen, J; Cheng, J; Lin, L; Liu, Z; Wang, B; Wei, H; Xie, B; Yang, Y; Yi, J; Zhao, H1
Li, H; Sun, H; Zhou, Y1
Dong, J; Jing, Y; Wang, R; Xu, L; Yu, Z1
Aller, P; Amrán, D; de Blas, E; Fernández, C; Sánchez, Y1
Cen, J; Chen, Z; Gu, M; Liu, D; Qi, X1
Chen, T; Fu, YL1
Ahuja, HG; Bailey, HH; Chang, JE; Kahl, BS; Kim, K; Kolesar, JM; Rodriguez, GA; Sanchez, FA; Voorhees, PM; Werndli, J1
MOESCHLIN, S1
JUDD, T; KIRSCHBAUM, A1
Lin, TH; Lu, FJ; Tseng, TH; Yin, YF1
Bowling, B; Doudican, NA; Orlow, SJ1
Cao, YX; Hao, JX; Li, J; Liu, SX1
Chen, B; Guo, D; Jiang, H; Song, W; Wang, X; Wu, C1
Jiang, J; Liu, XS; Peng, CY; Zheng, HT1
Bachleitner-Hofmann, T; Roth, E; Sturlan, S; Wessner, B; Wirtitsch, M1
Essers, MA; Trumpp, A1
Beitz, E; Mukhopadhyay, R1
Chen, L; Dong, Z; Meng, Q; Peng, Z; Si, J; Xia, Y1
Chung, JG; Huang, WW; Kuo, SC; Lai, IC; Lai, TY; Lin, CC; Lin, JJ; Wen, YF; Yang, JS1
Chen, G; Ho, PC; Liu, J; Shao, Y; Wu, J1
Arkusz, J; Ferlińska, M; Gradecka-Meesters, D; Smok-Pieniążek, A; Stańczyk, M; Stępnik, M1
Tang, X; Wang, C; Xiao, G; Yao, C1
Balayssac, S; Ballot, C; Briand, G; Dammak, A; Dauphin, V; Formstecher, P; Idziorek, T; Jendoubi, M; Joha, S; Jonneaux, A; Kluza, J; Maboudou, P; Malet-Martino, M; Marchetti, P; Quesnel, B1
Aller, P; Boyano-Adánez, Mdel C; Bréard, J; Calviño, E; de Blas, E; Estañ, MC; Sancho, P; Simón, GP1
Kwong, YL1
Liu, J; Liu, Y; Qu, J; Qu, X; Xu, L; Zhang, G; Zhang, Y; Zheng, H1
Chin, A; Ciancaglini, P; de Oliveira, KT; dos Santos, GA; Faça, VM; Falcão, RP; Ferreira, GA; Greene, LJ; Hanash, SM; Izumi, C; Leopoldino, AM; Rego, EM; Scheucher, PS; Simão, AM; Thomé, CH1
Aller, P; Boyano-Adánez, Mdel C; Calviño, E; de Blas, E; Estañ, MC; Gómez-Gómez, M; Mena, ML; Rial, E1
Chen, SY; Li, XM; Liu, SX1
Chang, IY; Hsieh, RK; Huang, MJ; Lin, CP; Liu, HJ1
Liu, XP; Narla, RK; Uckun, FM1
Bachleitner-Hofmann, T; Baumgartner, M; Roth, E; Sturlan, S1
Stull, DM1
An, S; Bae, IJ; Gwak, HS; Hong, SI; Lee, HC; Lee, SH; Park, IC; Park, MJ; Rhee, CH; Seo, KM; Woo, SH1
LEBON, J; MESSERSCHMITT, J1
Bai, D; Ge, J; Ma, L; Su, H; Wang, B; Wei, H; Yao, X; Zhao, H1
Shen, WL; Zhang, Y1
ENGLE, RL; LOTT, WA; REZNIKOFF, P; YALE, HL1
Lin, MF; Wei, GQ; Zhang, SL; Zou, DB1
Antony, S; Fu, H; Kohlhagen, G; Liao, Z; Liu, H; Pommier, Y; Sordet, O; Stevens, EV1
Billi, AM; Cappellini, A; Cocco, L; Falà, F; Manzoli, L; Martelli, AM; Tabellini, G; Tazzari, PL1
Pan, B; Xu, L; Yang, X1
Ma, H; Wang, C; Wang, XF; Wang, Y1
FLORIJN, E1
Chen, G; Chen, L; Chen, S; Li, X; Ni, J; Shen, Z; Tang, W; Wang, Z; Xiong, S; Zhong, H; Zhu, J1
Chen, SJ; Chen, Z; Dong, Y; Fang, J; Hu, J1
Liu, SX; Liu, Y; Ren, LF; Xiao, YF1
Baccarani, M; Billi, AM; Bortul, R; Evangelisti, C; Grafone, T; Martelli, AM; Martinelli, G; Tabellini, G; Tazzari, PL1
Cahill, S; Meyer, M; O'Dwyer, M; Samali, A; Szegezdi, E1
Chen, GQ; Huang, Y; Jiang, Y; Liu, W; Peng, ZG; Song, LP; Zhao, Q1
Jing, Y; Waxman, S; Wurmbach, E; Xia, L1
Moore, P; Tchounwou, PB; Yedjou, CG1
Meng, L; Meng, R; Sui, XH; Yang, BF; Zhou, J1
Duan, LN; Guo, ZK; Ji, SQ; Wang, HX1
Bauer, N; Bergmann, L; Chow, KU; Glienke, W1
Aller, P; Amrán, D; de Blas, E; Esteban, D; Fernandez, C; Palacios, MA; Ramos, AM1
Chan, R; Chen, D; Jing, Y; Waxman, S1
Seo, T; Ueda, T; Urasaki, Y1
Cui, X; Liu, T; Meng, WT; Xi, YM; Ye, XS1
Li, W; Meng, R; Sui, X; Yang, B; Zhou, J1
Aoki, M; Arai, A; Ichijo, H; Miura, O; Yan, W1
Astier, A; Gibaud, S1
Chen, GQ; Li, D; Liu, W; Wang, Y; Wang, YC; Wu, YL; Yan, H1
Berman, JN; Look, AT1
Czyz, M; Duechler, M; Stańczyk, M; Stepnik, M1
Chen, JP; Cong, YW; Dong, B; Fu, YL; Huang, R; Liang, YG; Liu, ZY; Mao, BZ; Shan, YJ; Wang, SQ; Xiao, H; Yu, ZY; Zhao, QS; Zhao, ZH1
Hampton, T1
Aller, P; Amrán, D; Bréard, J; Calle, C; de Blas, E; Fernández, C; Ramos, AM; Sánchez, Y1
Chen, FY; Han, JY; Huang, HH; Wang, HR; Zhong, H; Zhong, JH; Zhu, JY1
Chen, GQ; Wang, LS; Wu, YL; Yu, Y1
Chen, SJ; Chen, Z; Li, G; Zhou, GB1
Chen, SY; Dong, Y; Guo, WJ; Ma, LH; Wang, ZY1
Cai, YX; Fu, YB; Li, L; Meng, FY; Sun, QX1
TROPEANO, L1
Aller, P; Ramos, AM1
Ayzac, L; Bergeret, A; Bonhomme, I; Dananche, B; Fabry, J; Fevotte, J; Fière, D; Hours, M; Milan, JJ; Philippe, J1
Birchall, D; Farmer, P; Goldman, J; Meller, S; Piller, G; Treleaven, J1
Kwong, YL; Todd, D1
Adami, HO; Dich, J; Hanberg, A; Zahm, SH1
Conrad, ME1
Akao, Y; Nakagawa, Y; Yamada, H1
Cheson, BD; McBee, WL; Murgo, AJ1
Dias, S; Lam, G; Lane, WJ; Rafii, S; Roboz, GJ; Soignet, SL; Warrell, RP1
Bhalla, KN; Nguyen, D; Nimmanapalli, R; Perkins, C; Porosnicu, M; Worthington, E1
Bruey, JM; Corcos, L; Garrido, C; Leroy, I; Lizard, G; Miguet, C; Plenchette, S; Rébé, C; Solary, E; Sordet, O1
Barbey, JT1
Singer, JW1
Cai, X; Chen, G; Shen, Y1
Buyukececi, F; Omay, SB; Sanli, UA; Saydam, G; Terzioglu, E; Uslu, R; Yuksel, S1
Chen, GQ; Chen, SJ; Chen, Z; Shen, ZX; Sun, GL; Tong, JH; Wang, ZY1
Callas, P; Eskenazi, B; Harrison, R; Sharp, DS; Smith, AH1
Gordon, HL; Holder, BB; Ott, MG1
Jondorf, WR1
Gao, Z; He, Y; Hu, Y; Li, F; Li, H; Li, Y; Liu, L; Ma, D; Ma, G; Shi, J; Wang, C; Wang, S; Wei, W; Yu, S; Yue, H; Zhang, W; Zhao, C; Zhou, W1
Cheng, YY; Guo, HR; Li, CY; Lin, MH1
Cai, X; Jiang, M; Jiang, Y; Li, Y; Ma, X; Meng, G; Tan, Y; Wu, W; Yin, H; Yin, T; Zhang, H1
Ahangaran, N; Doosti-Irani, A; Khamutian, S; Khodabakhshi, M; Rahmani, A; Sahraeei, F; Shirmohammadi-Khorram, N; Shokoohizadeh, MJ1
Li, H; Sun, H; Tse, E; Wang, H; Zhou, Y1
Chen, SJ; Chen, Z; de Thé, H; Mao, JH; Zhang, XW; Zhou, GB1
BLOCK, M; JACOBSON, LO; NEAL, W1
MARCHAL, G1
MARINO, A; PREZIOSI, P1
KISELEVA, AN; KUZ'MIN, DS; POVERGO, NS; ROZANOVA, LM; SHERMAN, SI; VAKULENKO, AD2
BIRCHALL, R; CHRISTIANSON, HB1
TARCHIANI, G; VITALE, S1
HEISTER, B; NORDQVIST, P1
BLOCK, MH; JACOBSON, LO1
Grünwald, HW; Rosner, F1
Kjellson, L1
Zeng, H1
Hahn, GM; Mivechi, NF; Monson, JM1
Kohno, H; Taketani, S; Tokunaga, R; Yoshinaga, T1
Philipp, R1
Kobylinski, S1

Reviews

22 review(s) available for arsenic and Leucocythaemia

ArticleYear
[Research of traditional Chinese medicine in the treatment of leukemia: current status].
    Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, 2008, Volume: 6, Issue:8

    Topics: Arsenic Trioxide; Arsenicals; Diagnosis, Differential; Drug Resistance, Neoplasm; Drugs, Chinese Herbal; Humans; Leukemia; Medicine, Chinese Traditional; Oxides; Phytotherapy

2008
Targeting leukemic stem cells by breaking their dormancy.
    Molecular oncology, 2010, Volume: 4, Issue:5

    Topics: Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Drug Resistance, Neoplasm; Granulocyte Colony-Stimulating Factor; Humans; Interferon-alpha; Leukemia; Neoplastic Stem Cells; Oxides

2010
Metalloid transport by aquaglyceroporins: consequences in the treatment of human diseases.
    Advances in experimental medicine and biology, 2010, Volume: 679

    Topics: Animals; Aquaglyceroporins; Aquaporins; Arsenicals; Biological Transport; Humans; Leukemia; Metals; Models, Biological; Neoplasms; Parasites; Parasitic Diseases; Permeability

2010
The medicinal use of realgar (As₄S₄) and its recent development as an anticancer agent.
    Journal of ethnopharmacology, 2011, Jun-01, Volume: 135, Issue:3

    Topics: Antineoplastic Agents; Arsenic; Arsenic Trioxide; Arsenicals; History, 16th Century; History, 19th Century; History, 20th Century; History, 21st Century; History, Ancient; History, Medieval; Humans; Leukemia; Medicine, Traditional; Oxides; Sulfides

2011
Pathogenesis and treatment of leukemia: an Asian perspective.
    Expert opinion on therapeutic targets, 2012, Volume: 16 Suppl 1

    Topics: Arsenic Trioxide; Arsenicals; Asian People; Cell Proliferation; Humans; Leukemia; Leukemia, Large Granular Lymphocytic; Leukemia, Promyelocytic, Acute; Oxides; Recurrence; Tretinoin

2012
[A review of the research on malignant hemopathies treated with arsenium-containing Chinese drugs].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2000, Volume: 25, Issue:8

    Topics: Animals; Apoptosis; Arsenic Trioxide; Arsenicals; Humans; Leukemia; Leukemia, Promyelocytic, Acute; Materia Medica; Oxides; Sulfides; Tumor Cells, Cultured

2000
Targeted therapies for the treatment of leukemia.
    Seminars in oncology nursing, 2003, Volume: 19, Issue:2

    Topics: Alemtuzumab; Aminoglycosides; Anti-Bacterial Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Benzamides; Dose-Response Relationship, Drug; Drug Interactions; Gemtuzumab; Humans; Imatinib Mesylate; Leukemia; Nurse-Patient Relations; Nurse's Role; Oncology Nursing; Oxides; Patient Education as Topic; Piperazines; Prognosis; Pyrimidines; Randomized Controlled Trials as Topic; Tretinoin

2003
[Advances in the study on antineoplastic action of realgar].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2004, Volume: 27, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Humans; K562 Cells; Leukemia; Leukemia, Promyelocytic, Acute; Materia Medica; Oxides; Tumor Cells, Cultured

2004
Arsenic in cancer therapy.
    Anti-cancer drugs, 2005, Volume: 16, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Arsenicals; Clinical Trials as Topic; Dose-Response Relationship, Drug; Humans; Leukemia; Lymphoma; Multiple Myeloma

2005
Hypoxia inducible factor-1alpha and leukemic cell differentiation.
    Sheng li xue bao : [Acta physiologica Sinica], 2006, Feb-25, Volume: 58, Issue:1

    Topics: Animals; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Cell Transformation, Neoplastic; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Leukemia; Leukemia, Promyelocytic, Acute; Oxides

2006
Targeting transcription factors in acute leukemia in children.
    Current drug targets, 2007, Volume: 8, Issue:6

    Topics: Acute Disease; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Child; DNA Methylation; Drug Delivery Systems; Histone Deacetylase Inhibitors; Humans; Leukemia; Oxides; Transcription Factors; Tretinoin

2007
Leukemia, an effective model for chemical biology and target therapy.
    Acta pharmacologica Sinica, 2007, Volume: 28, Issue:9

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Benzamides; Dasatinib; Growth Inhibitors; Humans; Imatinib Mesylate; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Promyelocytic, Acute; Oxides; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Thiazoles; Tretinoin

2007
From dissection of disease pathogenesis to elucidation of mechanisms of targeted therapies: leukemia research in the genomic era.
    Acta pharmacologica Sinica, 2007, Volume: 28, Issue:9

    Topics: Animals; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Benzamides; Disease Models, Animal; Humans; Imatinib Mesylate; Leukemia; Oxides; Piperazines; Pyrimidines; Tretinoin

2007
Pesticides and cancer.
    Cancer causes & control : CCC, 1997, Volume: 8, Issue:3

    Topics: Animals; Arsenicals; Breast Neoplasms; Carcinogens; Causality; Chlordan; Creosote; DDT; Ditiocarb; Female; Herbicides; Hexachlorocyclohexane; Humans; Insecticides; Leukemia; Lung Neoplasms; Lymphoma; Lymphoma, Non-Hodgkin; Mutagens; Neoplasms; Neoplasms, Experimental; Occupational Diseases; Occupational Exposure; Ovarian Neoplasms; Pesticides; Phenols; Protective Devices; Sarcoma; Triazines

1997
Arsenic-induced apoptosis in malignant cells in vitro.
    Leukemia & lymphoma, 2000, Volume: 37, Issue:1-2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Caspases; Down-Regulation; Glutathione; Growth Inhibitors; Hematopoietic Stem Cells; Humans; Leukemia; Leukemia, B-Cell; Leukemia, Promyelocytic, Acute; Leukocytes, Mononuclear; Neuroblastoma; Oxides; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured

2000
Cardiac toxicity of arsenic trioxide.
    Blood, 2001, Sep-01, Volume: 98, Issue:5

    Topics: Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Artifacts; Electrocardiography; Electrolytes; Humans; Leukemia; Long QT Syndrome; Oxides; Torsades de Pointes

2001
Expanding the use of arsenic trioxide: leukemias and beyond.
    Seminars in hematology, 2002, Volume: 39, Issue:2 Suppl 1

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Humans; Leukemia; Leukemia, Promyelocytic, Acute; Multiple Myeloma; Neoplasms; Oxides

2002
Delayed health hazards of pesticide exposure.
    Annual review of public health, 1986, Volume: 7

    Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Agent Orange; Agricultural Workers' Diseases; Amitrole; Arsenicals; Chlorophenols; Dioxins; Europe; Herbicides; Humans; Insecticides; Leukemia; Neoplasms; Nervous System Diseases; New Zealand; Occupational Diseases; Organophosphate Poisoning; Pesticides; Polychlorinated Dibenzodioxins; Propane; Reproduction; Risk; Sweden; Time Factors; United States; Vietnam

1986
From an old remedy to a magic bullet: molecular mechanisms underlying the therapeutic effects of arsenic in fighting leukemia.
    Blood, 2011, Jun-16, Volume: 117, Issue:24

    Topics: Adult; Animals; Arsenic; Humans; Leukemia; Magic; Medicine, Traditional; Models, Biological; Models, Molecular; Signal Transduction; Treatment Outcome

2011
[INORGANIC ARSENIC IN THERAPY (WITH PARTICULAR ATTENTION TO ANTILEUKEMIC THERAPY)].
    La Clinica terapeutica, 1964, Oct-31, Volume: 31

    Topics: Arsenic; Attention; Drug Therapy; Leukemia; Neoplasms; Toxicology

1964
Cytotoxic drugs and leukaemogenesis.
    Clinics in haematology, 1980, Volume: 9, Issue:3

    Topics: Adult; Aged; Arsenic; Benzene; Bone Marrow; Breast Neoplasms; Female; Hodgkin Disease; Humans; Leukemia; Leukemia, Lymphoid; Lymphoma; Male; Melphalan; Middle Aged; Multiple Myeloma; Mycosis Fungoides; Ovarian Neoplasms; Paraproteinemias; Waldenstrom Macroglobulinemia

1980
Arsenic exposure: health effects and the risk of cancer.
    Reviews on environmental health, 1985, Volume: 5, Issue:1

    Topics: Absorption; Arsenic; Arsenic Poisoning; Diet; Gastrointestinal Neoplasms; Humans; Kidney Neoplasms; Leukemia; Liver Neoplasms; Mutagens; Neoplasms; Occupational Diseases; Respiratory Tract Neoplasms; Risk; Skin Neoplasms; Teratogens

1985

Trials

2 trial(s) available for arsenic and Leucocythaemia

ArticleYear
Phase II study of arsenic trioxide and ascorbic acid for relapsed or refractory lymphoid malignancies: a Wisconsin Oncology Network study.
    Hematological oncology, 2009, Volume: 27, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Female; Glutathione; Humans; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Lymphoma, Non-Hodgkin; Male; Middle Aged; Oxides; Safety

2009
Effects of arsenic trioxide administration styles on leukocytosis.
    Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih, 2006, Volume: 21, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Differentiation; Cell Line, Tumor; Humans; Infusions, Intravenous; K562 Cells; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Leukocytosis; Oxides

2006

Other Studies

109 other study(ies) available for arsenic and Leucocythaemia

ArticleYear
Structural Modification of Aminophenylarsenoxides Generates Candidates for Leukemia Treatment
    Journal of medicinal chemistry, 2021, 11-11, Volume: 64, Issue:21

    Topics: Antineoplastic Agents; Apoptosis; Arsenicals; HL-60 Cells; Humans; Leukemia; Molecular Docking Simulation; Molecular Structure; Oxidative Stress; Reactive Oxygen Species; Structure-Activity Relationship; Thioredoxin-Disulfide Reductase

2021
Evidence supporting that the attribution of first success in use of arsenic for the treatment of leukaemia should be to David Lissauer (1836-1892).
    Leukemia, 2022, Volume: 36, Issue:6

    Topics: Arsenic; Arsenicals; Humans; Leukemia; Leukemia, Promyelocytic, Acute; Oxides

2022
1,3-Benzodioxole Derivatives Improve the Anti-Tumor Efficiency of Arsenicals.
    International journal of molecular sciences, 2022, Jun-22, Volume: 23, Issue:13

    Topics: Animals; Apoptosis; Arsenicals; Dioxoles; Leukemia; Mice; Neoplasms

2022
A proteomics research of apoptosis of leukemia cells induced by arsenic trioxide.
    Cellular and molecular biology (Noisy-le-Grand, France), 2017, Mar-31, Volume: 63, Issue:3

    Topics: Amino Acid Sequence; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Shape; HL-60 Cells; Humans; Leukemia; Mass Spectrometry; Neoplasm Proteins; Oxides; Proteomics

2017
HOXA9 is critical in the proliferation, differentiation, and malignancy of leukaemia cells both in vitro and in vivo.
    Cell biochemistry and function, 2017, Volume: 35, Issue:7

    Topics: Animals; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Down-Regulation; HL-60 Cells; Homeodomain Proteins; Humans; Leukemia; Male; Mice; Mice, Nude; MicroRNAs; Oxides; RNA Interference; RNA, Messenger; Transplantation, Heterologous; Tretinoin

2017
Guo-Qiang Chen: haematologist who risked all for research success.
    Lancet (London, England), 2018, 04-14, Volume: 391, Issue:10129

    Topics: Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Biomedical Research; China; Hematology; History, 20th Century; History, 21st Century; Humans; Leukemia; Oxides; Portraits as Topic

2018
Realgar transforming solution as a novel arsenic agent with a lower risk of cardiotoxicity.
    Journal of pharmacological sciences, 2019, Volume: 140, Issue:2

    Topics: Animals; Arsenicals; Cardiotoxicity; Cell Proliferation; Cells, Cultured; Female; Humans; Leukemia; Long QT Syndrome; Male; Mice; Rats, Wistar; Risk; Solutions; Sulfides

2019
Artesunate possesses anti-leukemia properties that can be enhanced by arsenic trioxide.
    Leukemia & lymphoma, 2014, Volume: 55, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Artemisinins; Artesunate; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Synergism; Fas Ligand Protein; fas Receptor; Humans; K562 Cells; Leukemia; Oxides; Proto-Oncogene Proteins c-fos; U937 Cells

2014
[Apoptosis effects of drug sensitivity leukemia cells induced by nano-realgar].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2013, Volume: 38, Issue:13

    Topics: Apoptosis; Arsenicals; Cell Proliferation; Humans; K562 Cells; Leukemia; Nanotechnology; Proto-Oncogene Proteins c-bcl-2; Sulfides; Tumor Suppressor Protein p53

2013
Identifying arsenic trioxide (ATO) functions in leukemia cells by using time series gene expression profiles.
    Gene, 2014, Feb-10, Volume: 535, Issue:2

    Topics: Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Cluster Analysis; Computational Biology; Databases, Nucleic Acid; Gene Expression Regulation, Leukemic; Humans; K562 Cells; Leukemia; Molecular Sequence Annotation; Oxides; Time Factors; Transcriptome

2014
Investigation of the mechanism involved in the As2O3-regulated decrease in MDR1 expression in leukemia cells.
    Oncology reports, 2014, Volume: 31, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Binding Sites; Cell Line, Tumor; Drug Resistance, Neoplasm; HEK293 Cells; Humans; I-kappa B Kinase; K562 Cells; Leukemia; Molecular Sequence Data; Oxides; Phosphorylases; Phosphorylation; Promoter Regions, Genetic; Protein Binding; Sequence Analysis, DNA; Signal Transduction; Transcription Factor RelA; Tumor Necrosis Factor-alpha

2014
The growth-inhibitory and apoptosis-inducing effect of deferoxamine combined with arsenic trioxide on HL-60 xenografts in nude mice.
    Leukemia research, 2014, Volume: 38, Issue:9

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Proliferation; Deferoxamine; Female; HL-60 Cells; Humans; Leukemia; Mice; Mice, Inbred BALB C; Mice, Nude; Oxides; Xenograft Model Antitumor Assays

2014
Toward adjunctive therapy of acute myeloid leukemia: is it feasible?
    Leukemia research, 2014, Volume: 38, Issue:9

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Proliferation; Deferoxamine; Female; Humans; Leukemia; Oxides

2014
Sensitivity of leukemic T-cell lines to arsenic trioxide cytotoxicity is dependent on the induction of phosphatase B220/CD45R expression at the cell surface.
    Molecular cancer, 2014, Nov-19, Volume: 13

    Topics: Animals; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Death; Cell Line, Tumor; Cell Membrane; HSP70 Heat-Shock Proteins; Humans; Jurkat Cells; Leukemia; Leukocyte Common Antigens; Mice; Mice, Inbred MRL lpr; NF-kappa B; Oxides; T-Lymphocytes

2014
[Antileukemic].
    Nihon rinsho. Japanese journal of clinical medicine, 2015, Volume: 73 Suppl 2

    Topics: Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Benzoates; Humans; Leukemia; Oxides; Remission Induction; Tetrahydronaphthalenes; Tretinoin

2015
[Effect of arsenic trioxide on proliferation and apoptosis of human leukemia cell line MV4-11 cells].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2015, Volume: 36, Issue:7

    Topics: Apoptosis; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Humans; Leukemia; Oxides

2015
Ultrasensitive and selective assay of glutathione species in arsenic trioxide-treated leukemia HL-60 cell line by molecularly imprinted polymer decorated electrochemical sensors.
    Biosensors & bioelectronics, 2016, Jun-15, Volume: 80

    Topics: Acetylcysteine; Arsenic Trioxide; Arsenicals; Biosensing Techniques; Dielectric Spectroscopy; Glutathione; Glutathione Disulfide; HL-60 Cells; Humans; Leukemia; Molecular Imprinting; Oxides; Polymers

2016
Curcumin reduces the expression of survivin, leading to enhancement of arsenic trioxide-induced apoptosis in myelodysplastic syndrome and leukemia stem-like cells.
    Oncology reports, 2016, Volume: 36, Issue:3

    Topics: Apoptosis; Arsenic Trioxide; Arsenicals; Caspase 3; Cell Line, Tumor; Curcumin; Down-Regulation; Drug Synergism; Humans; Inhibitor of Apoptosis Proteins; Leukemia; Myelodysplastic Syndromes; Oxides; Poly(ADP-ribose) Polymerases; RNA, Small Interfering; Stem Cells; Survivin

2016
Differential expression and response to arsenic stress of MRPs and ASAN1 determine sensitivity of classical multidrug-resistant leukemia cells to arsenic trioxide.
    Leukemia research, 2016, Volume: 50

    Topics: Antineoplastic Agents; Arsenic; Arsenic Trioxide; Arsenicals; Arsenite Transporting ATPases; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Gene Expression; HL-60 Cells; Humans; K562 Cells; Leukemia; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Oxides

2016
Cytotoxicity of arsenic trioxide in single leukemia cells by time-resolved ICP-MS together with lanthanide tags.
    Chemical communications (Cambridge, England), 2017, Mar-07, Volume: 53, Issue:20

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Death; Cell Differentiation; Cell Line, Tumor; Cisplatin; HL-60 Cells; Humans; Lanthanoid Series Elements; Leukemia; Mass Spectrometry; Oxides; Single-Cell Analysis; Time Factors

2017
N-(beta-Elemene-13-yl)tryptophan methyl ester induces apoptosis in human leukemia cells and synergizes with arsenic trioxide through a hydrogen peroxide dependent pathway.
    Cancer letters, 2008, Sep-28, Volume: 269, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Caspase 3; Catalase; Cell Proliferation; Cell Survival; Drug Synergism; HL-60 Cells; Humans; Hydrogen Peroxide; Leukemia; Oxides; Sesquiterpenes; Tryptophan

2008
Genistein selectively potentiates arsenic trioxide-induced apoptosis in human leukemia cells via reactive oxygen species generation and activation of reactive oxygen species-inducible protein kinases (p38-MAPK, AMPK).
    International journal of cancer, 2008, Sep-01, Volume: 123, Issue:5

    Topics: AMP-Activated Protein Kinases; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Drug Synergism; Electrophoretic Mobility Shift Assay; Enzyme Activation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Genistein; HL-60 Cells; Humans; Immunoblotting; Jurkat Cells; Leukemia; Multienzyme Complexes; Oxidative Stress; Oxides; p38 Mitogen-Activated Protein Kinases; Protein Serine-Threonine Kinases; Reactive Oxygen Species; U937 Cells

2008
Expression of Dlk1 gene in myelodysplastic syndrome determined by microarray, and its effects on leukemia cells.
    International journal of molecular medicine, 2008, Volume: 22, Issue:1

    Topics: Adult; Aged; Antigens, CD34; Apoptosis; Arsenic Trioxide; Arsenicals; Calcium-Binding Proteins; Cell Cycle; Cell Proliferation; Female; Gene Expression Profiling; Gene Expression Regulation; Humans; Intercellular Signaling Peptides and Proteins; K562 Cells; Leukemia; Leukocytes, Mononuclear; Male; Membrane Proteins; Middle Aged; Myelodysplastic Syndromes; Oligonucleotide Array Sequence Analysis; Oxides; Tetradecanoylphorbol Acetate; Up-Regulation

2008
Therapy for Leukemia with X-rays, arsenic and Urethane.
    Helvetica medica acta, 1948, Volume: 15, Issue:2

    Topics: Arsenic; Arsenicals; Leukemia; Radiotherapy; Urethane

1948
Effect of urethane, X-rays, potassium arsenite, benzol, on survival time in transplanted mouse leukemia.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1948, Volume: 68, Issue:2

    Topics: Animals; Arsenicals; Arsenites; Benzene; Leukemia; Leukemia, Experimental; Potassium; Potassium Compounds; Urethane; X-Rays

1948
Enhancement of esculetin on arsenic trioxide-provoked apoptosis in human leukemia U937 cells.
    Chemico-biological interactions, 2009, Jun-15, Volume: 180, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Arsenic Trioxide; Arsenicals; Blotting, Western; Cell Survival; Fluorescent Antibody Technique; Humans; Leukemia; Oxides; U937 Cells; Umbelliferones

2009
Enhancement of arsenic trioxide cytotoxicity by dietary isothiocyanates in human leukemic cells via a reactive oxygen species-dependent mechanism.
    Leukemia research, 2010, Volume: 34, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Cell Death; Drug Synergism; Humans; Isothiocyanates; Leukemia; Oxides; Reactive Oxygen Species; Sulfides; Sulfones; Sulfoxides; Thiocyanates; Tumor Cells, Cultured; Vegetables

2010
[Comparison of the effect of arsenic sulfide on apoptosis and hTERT-mRNA expression in two leukemia cell lines].
    Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2009, Volume: 25, Issue:10

    Topics: Animals; Antineoplastic Agents; Apoptosis; Arsenicals; Cell Cycle; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Leukemia; RNA, Messenger; Sulfides; Telomerase

2009
Effect of colloidal gold nanoparticles on cell interface and their enhanced intracellular uptake of arsenic trioxide in leukemia cancer cells.
    Journal of nanoscience and nanotechnology, 2009, Volume: 9, Issue:8

    Topics: Arsenic Trioxide; Arsenicals; Colloids; Electrochemistry; Gold; Humans; K562 Cells; Leukemia; Metal Nanoparticles; Oxides

2009
Growth-inhibiting effects of arsenic trioxide plus epigenetic therapeutic agents on leukemia cell lines.
    Leukemia & lymphoma, 2010, Volume: 51, Issue:2

    Topics: Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Azacitidine; Cell Proliferation; Cell Survival; Decitabine; DNA Methylation; DNA Modification Methylases; DNA, Neoplasm; Drug Antagonism; Drug Synergism; Electrophoresis, Capillary; Growth Inhibitors; Histone Deacetylase Inhibitors; HL-60 Cells; Humans; Hydroxamic Acids; K562 Cells; Leukemia; Oxides; U937 Cells; Valproic Acid

2010
Omega-3 and omega-6 polyunsaturated fatty acids enhance arsenic trioxide efficacy in arsenic trioxide-resistant leukemic and solid tumor cells.
    Oncology research, 2009, Volume: 18, Issue:2-3

    Topics: Antineoplastic Agents; Apoptosis; Arachidonic Acid; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Synergism; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Humans; Leukemia; Lipid Peroxidation; Neoplasms; Oxides; Vitamin E

2009
Nuclear Factor-κB modulates cellular glutathione and prevents oxidative stress in cancer cells.
    Cancer letters, 2010, Dec-18, Volume: 299, Issue:1

    Topics: Animals; Arsenic Trioxide; Arsenicals; Glutathione; Humans; Leukemia; Male; Mice; NF-kappa B; Oxidative Stress; Oxides; Prostatic Neoplasms; Signal Transduction

2010
Arsenic trioxide (As₂O₃) inhibits murine WEHI-3 leukemia in BALB/c mice in vivo.
    Environmental toxicology, 2012, Volume: 27, Issue:6

    Topics: Animals; Antigens, Differentiation; Arsenic Trioxide; Arsenicals; B-Lymphocytes; Cell Differentiation; Cell Line, Tumor; Leukemia; Leukemia, Experimental; Macrophages; Male; Mice; Mice, Inbred BALB C; Oxides; Spleen; Tretinoin

2012
Assessment of the involvement of oxidative stress and Mitogen-Activated Protein Kinase signaling pathways in the cytotoxic effects of arsenic trioxide and its combination with sulindac or its metabolites: sulindac sulfide and sulindac sulfone on human leu
    Medical oncology (Northwood, London, England), 2012, Volume: 29, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Synergism; Glutathione; Humans; Leukemia; Mitogen-Activated Protein Kinases; Oxidative Stress; Oxides; Reactive Oxygen Species; Signal Transduction; Sulindac

2012
Potentiation of arsenic trioxide-induced apoptosis by 8-bromo-7-methoxychrysin in human leukemia cells involves depletion of intracellular reduced glutathione.
    Acta biochimica et biophysica Sinica, 2011, Volume: 43, Issue:9

    Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; bcl-2-Associated X Protein; bcl-X Protein; Blotting, Western; Cell Survival; Cytochromes c; Dose-Response Relationship, Drug; Drug Synergism; Flavonoids; Glutathione; HL-60 Cells; Humans; Intracellular Space; Jurkat Cells; Leukemia; Mitochondria; Oxides; Phosphorylation; Proto-Oncogene Proteins c-akt; Time Factors; U937 Cells; X-Linked Inhibitor of Apoptosis Protein

2011
Exploiting mitochondrial dysfunction for effective elimination of imatinib-resistant leukemic cells.
    PloS one, 2011, Volume: 6, Issue:7

    Topics: Animals; Arsenic Trioxide; Arsenicals; Benzamides; Cell Death; Cell Line, Tumor; Cell Respiration; Drug Resistance, Neoplasm; Electron Transport; Energy Metabolism; Glucose; Imatinib Mesylate; Isothiocyanates; Leukemia; Mice; Mitochondria; Models, Biological; Oxidative Stress; Oxides; Piperazines; Pyrimidines; Reactive Oxygen Species

2011
Increased apoptotic efficacy of lonidamine plus arsenic trioxide combination in human leukemia cells. Reactive oxygen species generation and defensive protein kinase (MEK/ERK, Akt/mTOR) modulation.
    Biochemical pharmacology, 2011, Dec-01, Volume: 82, Issue:11

    Topics: Apoptosis; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Drug Synergism; Extracellular Signal-Regulated MAP Kinases; Humans; Indazoles; Leukemia; Membrane Potential, Mitochondrial; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Oxidative Stress; Oxides; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction; TOR Serine-Threonine Kinases

2011
Cbl-b-dependent degradation of FLIP(L) is involved in ATO-induced autophagy in leukemic K562 and gastric cancer cells.
    FEBS letters, 2012, Sep-21, Volume: 586, Issue:19

    Topics: Adaptor Proteins, Signal Transducing; Arsenic Trioxide; Arsenicals; Autophagy; Base Sequence; CASP8 and FADD-Like Apoptosis Regulating Protein; Cell Line, Tumor; Cell Survival; Humans; Jurkat Cells; K562 Cells; Leukemia; Oxides; Proteasome Endopeptidase Complex; Proto-Oncogene Proteins c-cbl; RNA, Small Interfering; Signal Transduction; Stomach Neoplasms; Ubiquitin

2012
Linker for activation of T-cell family member2 (LAT2) a lipid raft adaptor protein for AKT signaling, is an early mediator of alkylphospholipid anti-leukemic activity.
    Molecular & cellular proteomics : MCP, 2012, Volume: 11, Issue:12

    Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Caspase 3; Cell Line; Cell Proliferation; Cholesterol; Enzyme Activation; Humans; Leukemia; Membrane Microdomains; Oxides; Phosphatidylinositol 3-Kinases; Phospholipids; Phosphorylcholine; Protein Structure, Tertiary; Proteome; Proto-Oncogene Proteins c-akt; RNA Interference; RNA, Small Interfering; Signal Transduction

2012
2-Deoxy-D-glucose cooperates with arsenic trioxide to induce apoptosis in leukemia cells: involvement of IGF-1R-regulated Akt/mTOR, MEK/ERK and LKB-1/AMPK signaling pathways.
    Biochemical pharmacology, 2012, Dec-15, Volume: 84, Issue:12

    Topics: Adenosine Triphosphate; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Division; Cell Line, Tumor; Deoxyglucose; Humans; Leukemia; Mitochondria; Oxidative Stress; Oxides; Protein Kinase Inhibitors; Protein Kinases; Receptor, IGF Type 1; Signal Transduction; TOR Serine-Threonine Kinases

2012
The cytotoxicity of arsenic trioxide to normal hematopoietic progenitors and leukemic cells is dependent on their cell-cycle status.
    Leukemia & lymphoma, 2002, Volume: 43, Issue:11

    Topics: Antigens, CD34; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Differentiation; Cell Division; Drug Resistance; Flow Cytometry; Hematopoietic Stem Cells; HL-60 Cells; Humans; Immunophenotyping; Interphase; Leukemia; Oxides

2002
Organic phenyl arsonic acid compounds with potent antileukemic activity.
    Bioorganic & medicinal chemistry letters, 2003, Feb-10, Volume: 13, Issue:3

    Topics: Antineoplastic Agents; Arsenicals; Cell Lineage; Genes, p53; Humans; Leukemia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured

2003
Docosahexaenoic acid enhances arsenic trioxide-mediated apoptosis in arsenic trioxide-resistant HL-60 cells.
    Blood, 2003, Jun-15, Volume: 101, Issue:12

    Topics: Antineoplastic Agents; Antioxidants; Apoptosis; Arsenic Trioxide; Arsenicals; bcl-2-Associated X Protein; Caspase 3; Caspases; Docosahexaenoic Acids; Drug Interactions; Drug Resistance, Neoplasm; HL-60 Cells; Humans; Leukemia; Lipid Peroxidation; Membrane Potentials; Mitochondria; Oleic Acid; Oxides; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Tumor Cells, Cultured; Vitamin E

2003
Tetraarsenic oxide induces apoptosis in U937 leukemic cells through a reactive oxygen species-dependent pathway.
    International journal of oncology, 2003, Volume: 23, Issue:4

    Topics: Apoptosis; Arsenic; Arsenic Trioxide; Arsenicals; Caspase 3; Caspases; Catalase; Cytochromes c; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Hydrogen Peroxide; Leukemia; Membrane Potentials; Mitochondria; Oxides; Reactive Oxygen Species; Time Factors; U937 Cells

2003
[Drug-induced aplastic myelosis; terminal acute myeloblstosis; pathogenic reflections].
    Le Sang, 1955, Volume: 26, Issue:8

    Topics: Arsenicals; Chloramphenicol; Humans; Leukemia; Leukemia, Myeloid

1955
Arsenic trioxide inhibits p-glycoprotein expression in multidrug-resistant human leukemia cells that overexpress the MDR1 gene.
    Chinese medical journal, 2003, Volume: 116, Issue:11

    Topics: Apoptosis; Arsenic Trioxide; Arsenicals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Drug Resistance, Multiple; Gene Expression; Genes, MDR; Humans; Leukemia; Oxides

2003
Bcl-2 antisense oligodeoxynucleotide increases the sensitivity of leukemic cells to arsenic trioxide.
    Cell biology international, 2003, Volume: 27, Issue:12

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Division; Cell Line, Tumor; DNA; Dose-Response Relationship, Drug; Flow Cytometry; Genetic Therapy; Humans; K562 Cells; Leukemia; Oligonucleotides, Antisense; Oxides; Proto-Oncogene Proteins c-bcl-2; Time Factors

2003
Comparative effectiveness of five newly synthesized arsenical compounds in treatment of leukemia in mice.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1952, Volume: 80, Issue:3

    Topics: Animals; Arsenicals; Leukemia; Leukemia, Experimental; Mice

1952
[Cytotoxic effects of arsenic trioxide in combination with chemotherapeutic drugs on acute non-promyelocytic leukemia cells].
    Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2004, Volume: 33, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Child; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Leukemia; Male; Middle Aged; Oxides

2004
Topoisomerase I-DNA complexes contribute to arsenic trioxide-induced apoptosis.
    The Journal of biological chemistry, 2004, Aug-06, Volume: 279, Issue:32

    Topics: Apoptosis; Arsenic Trioxide; Arsenicals; Blotting, Western; Buthionine Sulfoximine; Caspase 3; Caspase Inhibitors; Caspases; DNA; DNA Fragmentation; DNA Topoisomerases, Type I; Enzyme Activation; Enzyme Inhibitors; Flow Cytometry; Gene Expression; Gene Silencing; Humans; Leukemia; Oxides; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Recombinant Proteins; Tumor Cells, Cultured

2004
Phosphoinositide 3-kinase/Akt involvement in arsenic trioxide resistance of human leukemia cells.
    Journal of cellular physiology, 2005, Volume: 202, Issue:2

    Topics: Androstadienes; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Caspases; Cell Line, Tumor; Chromones; Drug Resistance; Enzyme Activation; Enzyme Inhibitors; HL-60 Cells; Humans; Leukemia; Morpholines; Mutation; NF-kappa B; NF-kappa B p50 Subunit; Oxides; Peptides; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoric Monoester Hydrolases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Transfection; Tumor Suppressor Proteins; Wortmannin

2005
Simultaneously multi-parameter determination of hematonosis cell apoptosis by two-photon and confocal laser scanning microscopy.
    Journal of clinical laboratory analysis, 2004, Volume: 18, Issue:5

    Topics: Apoptosis; Arsenic Trioxide; Arsenicals; Calcium; Cell Line, Tumor; Cell Nucleus; Dose-Response Relationship, Drug; Flow Cytometry; Hematologic Diseases; Humans; Leukemia; Membrane Potentials; Microscopy, Confocal; Mitochondria; Oxides; Photons

2004
On the action arsenite and urethane in leukaemia and polycythaemia.
    Acta haematologica, 1950, Volume: 3, Issue:5

    Topics: Arsenic; Arsenicals; Arsenites; Humans; Leukemia; Polycythemia; Urethane

1950
[Effects of arsenic trioxide on the subcellular localization of PML/PML-RARalpha protein in leukemic cells].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 1997, Volume: 18, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; HL-60 Cells; Humans; Intracellular Space; Leukemia; Nuclear Proteins; Oxides; Promyelocytic Leukemia Protein; Protein Transport; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Transcription Factors; Tretinoin; Tumor Suppressor Proteins

1997
[Effect of realgar on expression of survivin in leukemia cell lines and its significance].
    Zhongguo shi yan xue ye xue za zhi, 2005, Volume: 13, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Arsenicals; Blotting, Western; Caspase 3; Dose-Response Relationship, Drug; fas Receptor; Fluorescent Antibody Technique; HL-60 Cells; Humans; Immunohistochemistry; Inhibitor of Apoptosis Proteins; Jurkat Cells; Leukemia; Microtubule-Associated Proteins; Neoplasm Proteins; Sulfides; Survivin; Time Factors

2005
Phosphoinositide 3-kinase/Akt inhibition increases arsenic trioxide-induced apoptosis of acute promyelocytic and T-cell leukaemias.
    British journal of haematology, 2005, Volume: 130, Issue:5

    Topics: Apoptosis; Arsenic Trioxide; Arsenicals; Blotting, Western; Cell Line, Tumor; Flow Cytometry; Humans; In Situ Nick-End Labeling; Jurkat Cells; Leukemia; Leukemia, Promyelocytic, Acute; Leukemia, T-Cell; Oxides; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; RNA, Small Interfering; Signal Transduction; Transfection; Tumor Cells, Cultured

2005
TRAIL sensitisation by arsenic trioxide is caspase-8 dependent and involves modulation of death receptor components and Akt.
    British journal of cancer, 2006, Feb-13, Volume: 94, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Arsenic Trioxide; Arsenicals; Caspase 8; Caspase Inhibitors; Caspases; Cell Line, Tumor; Humans; Leukemia; Membrane Glycoproteins; Oligopeptides; Oncogene Protein v-akt; Oxides; Phosphorylation; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha

2006
Upregulation of Bfl-1/A1 in leukemia cells undergoing differentiation by all-trans retinoic acid treatment attenuates chemotherapeutic agent-induced apoptosis.
    Leukemia, 2006, Volume: 20, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Doxorubicin; Gene Silencing; HL-60 Cells; Humans; Leukemia; Minor Histocompatibility Antigens; Oxides; Paclitaxel; Proto-Oncogene Proteins c-bcl-2; RNA, Small Interfering; Tretinoin; Up-Regulation

2006
Dose- and time-dependent response of human leukemia (HL-60) cells to arsenic trioxide treatment.
    International journal of environmental research and public health, 2006, Volume: 3, Issue:2

    Topics: Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; HL-60 Cells; Humans; Leukemia; Oxides

2006
Arsenic trioxide-responsive leukemia cutis in a patient with acute promyelocytic leukemia after ATRA treatment.
    Leukemia & lymphoma, 2006, Volume: 47, Issue:7

    Topics: Adolescent; Anthracyclines; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Cytarabine; Female; Humans; Leukemia; Leukemia, Promyelocytic, Acute; Oxides; Risk; Skin; Tretinoin

2006
Down-regulation of wt1 expression in leukemia cell lines as part of apoptotic effect in arsenic treatment using two compounds.
    Leukemia & lymphoma, 2006, Volume: 47, Issue:8

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Arsenic Trioxide; Arsenicals; Arsenites; Carrier Proteins; Co-Repressor Proteins; Cytoskeletal Proteins; Gene Expression Regulation; HL-60 Cells; Humans; K562 Cells; Leukemia; Oxides; Sodium Compounds; WT1 Proteins

2006
Pharmacologic inhibitors of extracellular signal-regulated kinase (ERKs) and c-Jun NH(2)-terminal kinase (JNK) decrease glutathione content and sensitize human promonocytic leukemia cells to arsenic trioxide-induced apoptosis.
    Journal of cellular physiology, 2006, Volume: 209, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Glutathione; Humans; JNK Mitogen-Activated Protein Kinases; Leukemia; Leukemia, Promyelocytic, Acute; Oxides; Peroxides; Reactive Oxygen Species

2006
Buthionine sulfoximine enhancement of arsenic trioxide-induced apoptosis in leukemia and lymphoma cells is mediated via activation of c-Jun NH2-terminal kinase and up-regulation of death receptors.
    Cancer research, 2006, Dec-01, Volume: 66, Issue:23

    Topics: Amino Acid Chloromethyl Ketones; Anthracenes; Apoptosis; Arsenic Trioxide; Arsenicals; Blotting, Western; Buthionine Sulfoximine; Caspase 3; Caspase Inhibitors; Cell Proliferation; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Glutathione; Humans; Hydrogen Peroxide; JNK Mitogen-Activated Protein Kinases; Jurkat Cells; Leukemia; Lymphoma; Oxides; Receptors, TNF-Related Apoptosis-Inducing Ligand; Time Factors; U937 Cells

2006
Establishment of an arsenic trioxide-resistant human leukemia cell line that shows multidrug resistance.
    International journal of hematology, 2007, Volume: 85, Issue:1

    Topics: Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Clone Cells; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Leukemia; Multidrug Resistance-Associated Proteins; Oxides; Vincristine

2007
[Methylation of P15INK4B gene in patients with myelodysplastic syndromes and demethylating effects of drugs].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2007, Volume: 38, Issue:1

    Topics: Arsenic Trioxide; Arsenicals; Azacitidine; Cyclin-Dependent Kinase Inhibitor p15; Decitabine; Disease Progression; DNA Methylation; Genetic Predisposition to Disease; Humans; Leukemia; Myelodysplastic Syndromes; Oxides

2007
Various tolerances to arsenic trioxide between human cortical neurons and leukemic cells.
    Science in China. Series C, Life sciences, 2006, Volume: 49, Issue:6

    Topics: Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Calcium; Cell Line, Tumor; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Tolerance; Humans; Leukemia; Neurons; Oxides

2006
ASK1 is activated by arsenic trioxide in leukemic cells through accumulation of reactive oxygen species and may play a negative role in induction of apoptosis.
    Biochemical and biophysical research communications, 2007, Apr-20, Volume: 355, Issue:4

    Topics: Animals; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Line; Enzyme Activation; Humans; JNK Mitogen-Activated Protein Kinases; Leukemia; MAP Kinase Kinase Kinase 5; Mice; Oxides; p38 Mitogen-Activated Protein Kinases; Reactive Oxygen Species; RNA, Small Interfering

2007
[Organoarsenicals derived from 2-phenyl-[1,3,2]dithiarsolan-4-yl)-methanol (AsIII) with antileukaemic properties: from trypanosomicides to anticancer drugs].
    Annales pharmaceutiques francaises, 2007, Volume: 65, Issue:3

    Topics: Animals; Antineoplastic Agents; Arsenicals; Humans; Leukemia; Trypanocidal Agents

2007
Arsenic trioxide and proteasome inhibitor bortezomib synergistically induce apoptosis in leukemic cells: the role of protein kinase Cdelta.
    Leukemia, 2007, Volume: 21, Issue:7

    Topics: Adult; Apoptosis; Arsenic Trioxide; Arsenicals; Boronic Acids; Bortezomib; Cell Line, Tumor; Drug Synergism; Enzyme Activation; Humans; Leukemia; Middle Aged; Mitogen-Activated Protein Kinases; Oxides; Protease Inhibitors; Protein Kinase C-delta; Pyrazines; Tumor Cells, Cultured

2007
Potentiation of arsenic trioxide cytotoxicity by Parthenolide and buthionine sulfoximine in murine and human leukemic cells.
    Cancer chemotherapy and pharmacology, 2008, Volume: 61, Issue:5

    Topics: Adenosine Triphosphate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Buthionine Sulfoximine; Cell Death; Cell Line, Tumor; DNA Fragmentation; Drug Synergism; Flow Cytometry; Glutamate-Cysteine Ligase; Glutathione; Humans; Leukemia; Mice; Microscopy, Fluorescence; NF-kappa B; Oxides; Reactive Oxygen Species; Sesquiterpenes

2008
Melissoidesin G, a diterpenoid purified from Isodon melissoides, induces leukemic-cell apoptosis through induction of redox imbalance and exhibits synergy with other anticancer agents.
    International journal of cancer, 2007, Nov-01, Volume: 121, Issue:9

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Caspases; Cytochromes c; Diterpenes; Glutathione; Humans; Isodon; Leukemia; Mitochondria; Molecular Structure; Oxidation-Reduction; Oxides; Phytotherapy; Tumor Cells, Cultured

2007
Cancer agents show first-line potential.
    JAMA, 2007, Jul-25, Volume: 298, Issue:4

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Bevacizumab; Dasatinib; Humans; Kidney Neoplasms; Leukemia; Oxides; Pyrimidines; Thiazoles

2007
Arsenic trioxide sensitizes promonocytic leukemia cells to TNFalpha-induced apoptosis via p38-MAPK-regulated activation of both receptor-mediated and mitochondrial pathways.
    Biochimica et biophysica acta, 2007, Volume: 1773, Issue:11

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Cytokines; Enzyme Activation; Enzyme Inhibitors; Glutathione; Humans; Leukemia; MAP Kinase Signaling System; Mitochondria; Myeloid Cells; NF-kappa B; Oxides; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Receptors, Cell Surface; Tumor Necrosis Factor-alpha

2007
[Correlation between expression of apoptosis-related gene pnas-2 and leukemia].
    Zhongguo shi yan xue ye xue za zhi, 2007, Volume: 15, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Arsenicals; Female; Humans; K562 Cells; Leukemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Sulfides; Tumor Cells, Cultured; U937 Cells; Young Adult

2007
[Effects of arsenic trioxide and ATRA on PLZF-RARalpha-positive U937 leukemic cells].
    Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2007, Volume: 23, Issue:9

    Topics: Antigens, CD; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Cell Cycle; Cell Proliferation; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Kruppel-Like Transcription Factors; Leukemia; Nitroblue Tetrazolium; Oxidation-Reduction; Oxides; Promyelocytic Leukemia Zinc Finger Protein; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Tetracycline; Tretinoin; U937 Cells

2007
[Effect of bortezomib used alone or in combination with arsenic trioxide on HL-60 cell xenograft in nude mice].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2007, Volume: 27, Issue:10

    Topics: Animals; Apoptosis; Arsenic Trioxide; Arsenicals; Boronic Acids; Bortezomib; Cell Proliferation; Disease Models, Animal; HL-60 Cells; Humans; Leukemia; Male; Mice; Mice, Nude; Oxides; Pyrazines; Random Allocation; Xenograft Model Antitumor Assays

2007
Potassium arsenite, Fowler's arsenical liqueur, in the treatment of chronic leukemic myelosis.
    Il Progresso medico, 1949, Volume: 5, Issue:11

    Topics: Amebicides; Antiprotozoal Agents; Antitrichomonal Agents; Arsenic; Arsenicals; Leukemia

1949
Quercetin decreases intracellular GSH content and potentiates the apoptotic action of the antileukemic drug arsenic trioxide in human leukemia cell lines.
    Biochemical pharmacology, 2008, May-15, Volume: 75, Issue:10

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; bcl-2-Associated X Protein; Cell Line, Tumor; Drug Synergism; Flavonoids; Glutathione; Humans; Leukemia; Membrane Potential, Mitochondrial; Oxides; Protein Kinases; Quercetin

2008
[Occupational exposure and malignant hemopathies: a case-control study in Lyon (France)].
    Revue d'epidemiologie et de sante publique, 1995, Volume: 43, Issue:3

    Topics: Adult; Aged; Alkalies; Arsenicals; Case-Control Studies; Dose-Response Relationship, Drug; Dust; Female; Humans; Ink; Leukemia; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Middle Aged; Mineral Oil; Occupational Exposure; Odds Ratio

1995
Arsenic and Ayurveda.
    Leukemia & lymphoma, 1993, Volume: 10, Issue:4-5

    Topics: Antineoplastic Agents; Arsenicals; Blood Cell Count; Child; History, 19th Century; History, 20th Century; History, Ancient; Humans; India; Keratosis; Leukemia; Medicine, Ayurvedic; Metals; Pigmentation Disorders; Plants, Medicinal; Splenomegaly; Sulfur

1993
Delicious poison: arsenic trioxide for the treatment of leukemia.
    Blood, 1997, May-01, Volume: 89, Issue:9

    Topics: Adult; Antineoplastic Agents; Apoptosis; Arsenic Poisoning; Arsenic Trioxide; Arsenicals; Cell Differentiation; Fatal Outcome; Humans; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukocytosis; Male; Oxides; Splenomegaly

1997
Treatment of acute promyelocytic leukemia with arsenic trioxide.
    The New England journal of medicine, 1999, Apr-01, Volume: 340, Issue:13

    Topics: Antineoplastic Agents; Arsenic; Arsenic Trioxide; Arsenicals; History, 16th Century; History, 18th Century; History, 19th Century; History, 20th Century; Humans; Leukemia; Leukemia, Promyelocytic, Acute; Oxides; Remission Induction

1999
Clinical trials referral resource. Clinical trials with arsenic trioxide.
    Oncology (Williston Park, N.Y.), 2000, Volume: 14, Issue:2

    Topics: Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Clinical Trials as Topic; Female; Humans; Leukemia; Lymphoma; Multiple Myeloma; Neoplasms; Oxides; Urogenital Neoplasms; Uterine Cervical Neoplasms

2000
Arsenic trioxide induces dose- and time-dependent apoptosis of endothelium and may exert an antileukemic effect via inhibition of angiogenesis.
    Blood, 2000, Aug-15, Volume: 96, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Leukemia; Neovascularization, Pathologic; Oxides; Time Factors

2000
Co-treatment with As2O3 enhances selective cytotoxic effects of STI-571 against Brc-Abl-positive acute leukemia cells.
    Leukemia, 2001, Volume: 15, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Arsenic Trioxide; Arsenicals; bcl-X Protein; Benzamides; Drug Synergism; Fusion Proteins, bcr-abl; Hemoglobins; Humans; Imatinib Mesylate; Leukemia; Macrophage-1 Antigen; Oxides; Piperazines; Protein Serine-Threonine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Pyrimidines; Tumor Cells, Cultured; X-Linked Inhibitor of Apoptosis Protein

2001
Mitochondria-targeting drugs arsenic trioxide and lonidamine bypass the resistance of TPA-differentiated leukemic cells to apoptosis.
    Blood, 2001, Jun-15, Volume: 97, Issue:12

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Caspases; Cell Differentiation; Cell-Free System; Drug Resistance; Etoposide; Humans; Indazoles; Leukemia; Mitochondria; Oxides; Proto-Oncogene Proteins c-bcl-2; Tetradecanoylphorbol Acetate; U937 Cells

2001
Cardiac toxicity of arsenic trioxide.
    Blood, 2001, Sep-01, Volume: 98, Issue:5

    Topics: Adverse Drug Reaction Reporting Systems; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Drug Approval; Drug Industry; Drug Labeling; Electrocardiography; Electrolytes; Humans; Leukemia; Long QT Syndrome; Oxides; Practice Guidelines as Topic; Safety; Torsades de Pointes; United States; United States Food and Drug Administration

2001
[Glutathione synthesis inhibitor enhances arsenic trioxide-induced apoptosis].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1999, Volume: 21, Issue:4

    Topics: Apoptosis; Arsenic Trioxide; Arsenicals; Buthionine Sulfoximine; Glutathione; Humans; Leukemia; Lymphoma; Oxides; Tumor Cells, Cultured

1999
Arsenic trioxide and methylprednisolone use different signal transduction pathways in leukemic differentiation.
    Leukemia research, 2002, Volume: 26, Issue:4

    Topics: Anti-Inflammatory Agents; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Cell Differentiation; Dose-Response Relationship, Drug; HL-60 Cells; Humans; K562 Cells; Leukemia; Methylprednisolone; Oxides; Phosphoprotein Phosphatases; Signal Transduction

2002
Respiratory cancer and occupational exposure to arsenicals.
    Archives of environmental health, 1974, Volume: 29, Issue:5

    Topics: Adult; Aged; Arsenicals; Cardiovascular Diseases; Dose-Response Relationship, Drug; Environmental Exposure; Female; Gastrointestinal Diseases; Gastrointestinal Neoplasms; Humans; Leukemia; Male; Middle Aged; Occupational Diseases; Respiratory Tract Diseases; Respiratory Tract Neoplasms; Retrospective Studies; Time Factors; Urogenital Neoplasms

1974
A possible unifying principle in the chemotherapy of certain protozoal diseases and of leukemia.
    The Medical annals of the District of Columbia, 1969, Volume: 38, Issue:2

    Topics: Amebiasis; Arsenicals; Folic Acid; Folic Acid Antagonists; Humans; Leukemia; Trypanosomiasis, African

1969
Ferritin-based targeted delivery of arsenic to diverse leukaemia types confers strong anti-leukaemia therapeutic effects.
    Nature nanotechnology, 2021, Volume: 16, Issue:12

    Topics: Adolescent; Adult; Aged; Animals; Antigens, CD; Antineoplastic Agents; Arsenic; Cell Death; Cell Line, Tumor; Child; Drug Delivery Systems; Female; Ferritins; Humans; Leukemia; Male; Mice, SCID; Middle Aged; Nanomedicine; Receptors, Transferrin; Xenograft Model Antitumor Assays; Young Adult

2021
Arsenic in Drinking Water and Incidences of Leukemia and Lymphoma: Implication for Its Dual Effects in Carcinogenicity.
    Frontiers in public health, 2022, Volume: 10

    Topics: Arsenic; Carcinogenesis; Drinking Water; Female; Hematologic Neoplasms; Humans; Incidence; Leukemia; Lymphoma; Male; Neoplasms

2022
Phase separation is required for PML nuclear body biogenesis and function.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2023, Volume: 37, Issue:6

    Topics: Apoptosis; Arsenic; Humans; Leukemia; Promyelocytic Leukemia Nuclear Bodies

2023
The association of arsenic exposure with mortality due to cancer, diabetes, Alzheimer's and congenital anomalies using Poisson regression.
    Scientific reports, 2023, 09-19, Volume: 13, Issue:1

    Topics: Alzheimer Disease; Arsenic; Brain Neoplasms; Diabetes Mellitus; Humans; Leukemia

2023
Cell Cycle-Dependent Uptake and Cytotoxicity of Arsenic-Based Drugs in Single Leukemia Cells.
    Analytical chemistry, 2018, 09-04, Volume: 90, Issue:17

    Topics: Antineoplastic Agents; Arsenic; Cell Cycle; Flow Cytometry; Humans; Leukemia; Mass Spectrometry

2018
Biological studies with arsenic. IV. The histopathologic effect of arsenic 76 upon the hematopoietic tissues of patients with leukemia.
    The Journal of laboratory and clinical medicine, 1953, Volume: 41, Issue:4

    Topics: Arsenic; Bone Marrow; Hematopoietic System; Leukemia; Radiation; Radioisotopes

1953
[Radioactive phosphorus and radioactive arsenic in the treatment of malignant blood diseases].
    La Revue du praticien, 1952, Sep-21, Volume: 2, Issue:24

    Topics: Arsenic; Hematologic Diseases; Hodgkin Disease; Humans; Leukemia; Phosphorus; Polycythemia Vera; Radioisotopes

1952
[Modern status of arsenic in the treatment of leukemia].
    La Riforma medica, 1957, Feb-09, Volume: 71, Issue:6

    Topics: Arsenic; Humans; Leukemia

1957
[Comparative evaluation of the effectiveness of certain therapeutic methods in chronic leukemias; roentgen rays, radioactive phosphorus, urethane, embichine, arsenic, myleran. IV].
    Problemy gematologii i perelivaniia krovi, 1959, Volume: 4, Issue:1

    Topics: Arsenic; Busulfan; Chronic Disease; Leukemia; Phosphorus; Phosphorus, Dietary; Radioactivity; Urethane; X-Rays

1959
[Comparative evaluation of the effectiveness of certain therapeutic methods in chronic leukemias; roentgen rays, radioactive phosphorus, urethane, embichine, arsenic, myleran. V].
    Problemy gematologii i perelivaniia krovi, 1959, Volume: 4, Issue:5

    Topics: Arsenic; Busulfan; Chronic Disease; Leukemia; Phosphorus; Phosphorus, Dietary; Radioactivity; Urethane; X-Rays

1959
NEPHROCUTANEOUS SYNDROMES.
    Southern medical journal, 1964, Volume: 57

    Topics: Amyloidosis; Anemia; Anemia, Sickle Cell; Angiokeratoma; Arachnodactyly; Arsenic; Blood Protein Disorders; Collagen Diseases; Dermatology; Drug Hypersensitivity; Ehlers-Danlos Syndrome; Glomerulonephritis; Humans; Kidney Diseases; Leukemia; Lupus Erythematosus, Systemic; Marfan Syndrome; Metabolic Diseases; Multiple Myeloma; Neurofibromatoses; Pseudoxanthoma Elasticum; Purpura; Pyelonephritis; Skin Neoplasms; Toxicology; Tuberous Sclerosis; Vascular Diseases

1964
[Treatment of leukemia with arsenic plus sulfonamide preparations].
    Nordisk medicin, 1962, Jul-12, Volume: 68

    Topics: Arsenic; Leukemia; Sulfanilamide; Sulfanilamides; Sulfonamides

1962
The use of radioarsenic (As76) in the treatment of leucemia and allied disorders of the hematopoietic tissues.
    The Journal of laboratory and clinical medicine, 1948, Volume: 33, Issue:12

    Topics: Arsenic; Arylsulfonates; Elements, Radioactive; Leukemia

1948
[Arsenic, leukemia and old horses].
    Lakartidningen, 1999, Jun-23, Volume: 96, Issue:25

    Topics: Arsenic; Fatigue Syndrome, Chronic; Humans; Leukemia; Trace Elements

1999
Arsenic suppresses necrosis induced by selenite in human leukemia HL-60 cells.
    Biological trace element research, 2001, Volume: 83, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Arsenic; Cations; DNA-Binding Proteins; DNA, Neoplasm; Drug Interactions; Heat Shock Transcription Factors; HL-60 Cells; Humans; JNK Mitogen-Activated Protein Kinases; Leukemia; Mitogen-Activated Protein Kinases; Necrosis; NF-kappa B; Signal Transduction; Sodium Selenite; Transcription Factor AP-1; Transcription Factors

2001
Expression of HSP-28 and three HSP-70 genes during the development and decay of thermotolerance in leukemic and nonleukemic human tumors.
    Cancer research, 1991, Dec-15, Volume: 51, Issue:24

    Topics: Arsenic; Arsenites; Base Sequence; Cell Survival; Electrophoresis, Gel, Two-Dimensional; Gene Expression; Heat-Shock Proteins; Hot Temperature; Humans; Hyperthermia, Induced; In Vitro Techniques; Leukemia; Molecular Sequence Data; Neoplasms; Oligodeoxyribonucleotides; Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Sodium Compounds; Tumor Cells, Cultured

1991
The human 32-kDa stress protein induced by exposure to arsenite and cadmium ions is heme oxygenase.
    FEBS letters, 1989, Mar-13, Volume: 245, Issue:1-2

    Topics: Anions; Arsenic; Arsenites; Cadmium; Cations; Cobalt; Electrophoresis, Polyacrylamide Gel; Heat-Shock Proteins; HeLa Cells; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hot Temperature; Humans; Immunoblotting; Leukemia; Mixed Function Oxygenases; Molecular Weight; Tumor Cells, Cultured

1989
[Therapy related changes in leukemias].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1967, Jan-15, Volume: 22, Issue:2

    Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Antineoplastic Agents; Arsenic; Chemical and Drug Induced Liver Injury; Cushing Syndrome; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Leukemia; Male; Middle Aged; Osteosclerosis; Peptic Ulcer; Prednisone; Radiotherapy; Sepsis; Thromboembolism; Transfusion Reaction

1967