Page last updated: 2024-08-26

arsenic and Acute Liver Injury, Drug-Induced

arsenic has been researched along with Acute Liver Injury, Drug-Induced in 96 studies

Research

Studies (96)

Timeframe	Studies, this research(%)	All Research%
pre-1990	27 (28.13)	18.7374
1990's	5 (5.21)	18.2507
2000's	17 (17.71)	29.6817
2010's	34 (35.42)	24.3611
2020's	13 (13.54)	2.80

Authors

Authors	Studies
Guo, H; Huo, T; Jiang, H; Li, A; Li, J; Wu, X; Yang, J; Zhang, Y	1
Fang, Y; Feng, C; Huo, TG; Jiang, H; Zhang, YH	1
Chen, M; Fang, Y; Feng, C; Huo, T; Jiang, H; Wang, S; Wang, Y; Yuan, M; Zhang, Y	1
Chen, K; Feng, T; Ling, S; Liu, J; Liu, P; Shan, Q; Song, P; Xiang, P; Xie, H; Xu, X; Zhang, X; Zheng, S; Zhou, L	1
Antony, KL; Augustine, P; Joy, AK; Paramaguru, R; Philips, CA	1
Ishii, K; Iwasaki, N; Masuda, T; Morishita, Y; Shibata, Y; Tamaoka, A	1
Gao, C; Li, W; Luo, Y; Shen, J; Tsoi, B; Wang, S; Yang, D	1
Ma, H; Yang, J	1
Bott, AJ; Catanzaro, JM; Chen, JS; Diaz-Meco, MT; Ding, WX; Dou, Z; Du, C; Jaber, N; Jiang, YP; Lin, RZ; Moscat, J; Ozato, K; Pan, JA; Sun, Y; Yang, B; Zong, WX	1
Chen, M; Fang, Y; Feng, C; Huo, T; Jiang, H; Wang, S; Wang, Y; Xiong, Z; Yuan, M; Zhang, Y; Zhao, L	1
Fan, L; Feng, H; Jia, B; Lan, F; Li, L; Liu, Q; Wang, T; Wang, Y; Xiao, W; Xing, G; Ye, W; Yue, X; Zhao, L; Zhou, C	1
He, X; Huang, H; Liu, W; Wang, J; Wei, Z; Yang, Z; Zhang, J; Zhang, Y	1
Bazarbachi, A; de Thé, H; El Hajj, H; Farid, R; Hatoum, H; Hermine, O; Kchour, G; Kooshyar, MM; Mahmoudi, M; Maleki, M; Rafatpanah, H; Rahimi, H; Rezaee, SA; Shirdel, A; Tarhini, M; Wattel, E; Yazdi, MT	1
Bowen, D; Burnett, AK; Cahalin, P; Craig, J; Hills, RK; Hunter, A; Kell, J; McMullin, MF; Milligan, D; Russell, N; Wheatley, K; Yin, J	1
Abhilash, M; Abhilash, S; Manju, A; Mathews, VV; Nair, RH; Paul, MS	1
SPELLBERG, MA	1
CAROLI, J; OPOLON, P	1
Achanzar, WE; Chen, H; Cheng, ML; Diwan, BA; Liu, J; Waalkes, MP; Xie, Y; Zhou, YS	1
De Capitani, EM; Kira, CS; Madureira, PR; Mello, SM; Soubhia, PC; Toledo, AS; Vieira, RJ	1
Bajel, A; Chandy, M; Desire, S; George, B; Lakshmi, KM; Mathews, V; Rao, JG; Srivastava, A; Srivastava, VM; Viswabandya, A	1
Cachin, M	1
Winship, KA	1
Calmus, Y; Poupon, R	1
Inns, RH; Rice, P	1
Apostoli, P; Brugnone, F; Kovacic, M; Martini, S; Romeo, L	1
Flora, SJ; Kannan, GM; Kumar, P	1
Chen, YC; Huan, SY; Yang, CH	1
Bukhsh, AR; Kundu, SN; Mitra, K	1
Chen, Y; He, Z; Liu, X; Qian, J; Qin, S; Shao, Z; Wang, L	1
Chauhan, RS; Dubey, R; Flora, SJ; Jaiswal, DK; Kannan, GM; Pant, BP	1
Horsley, S; Lewis, M; McHugh, P; Parsons, V; Thould, A; Tubbs, H; Wilkinson, SP; Williams, R; Winterton, M	1
Berk, PD; Creech, J; Falk, H; Martin, JF; Popper, H; Selikoff, IJ; Thomas, L; Watanabe, P; Young, RS	1
Cote, J; Guillaume, E; Huet, PM; Lavoie, P; Légaré, A; Viallet, A	1
Dyan, S; Labadie, H; Licht, H; Novello, P; Pouteau, M	1
Arpin, MP; Biour, M; Bockel, R; Charrault, A; Doffoël, M; Vetter, D	1
Nyfors, A; Sogaard, H; Zachariae, H	1
Fossati, C	1
Cornelius, CE; Himes, JA	1
Efrain Salvioli, J	1
Ruyters, L	1
Zimmerman, HJ	1
Ahmad, MH; Ahmad, RS; Anwar, H; Haleem, MA; Imran, M; Khan, MK; Khan, SA; Naqvi, SAR; Nisa, MU	1
Chen, P; Chen, R; Nie, Y; Song, S; Yang, Y	1
Hu, L; Huang, R; Rao, G; Ruan, Z; Tang, L; Tang, Z; Wu, S; Zhong, G	1
Khodayar, MJ; Khorsandi, L; Mahdavinia, M; Neisi, N; Nikravesh, M	1
Chen, S; Cheng, W; He, T; Liu, J; Wang, X; Wang, Y; Zhang, J	1
Azadnasab, R; Daryagasht, M; Khodayar, MJ; Khorsandi, L; Moosavi, M	1
Abel, P; Annamalai, S; Balachandar, V; Elangovan, A; Madhyastha, H; Madhyastha, R; Maruyama, M; Namachivayam, A; Ramesh, S; Renu, K; Saravanan, A; Valsala Gopalakrishnan, A	1
Abdel Moneim, AE; Al Aboud, D; Alsharif, KF; Amin, HK; Baty, RS; Elmahallawy, EK; Habotta, OA; Hassan, KE; Kassab, RB; Zhery, AS	1
Wang, Q; Wang, W; Wei, S; Yang, Y; Zeng, Q; Zhang, A	1
Hu, Y; Xiao, T; Zhang, A	1
Chakraborty, R; Famurewa, AC; George, A; Koti, R; Madhyastha, H; Myakala, H; Renu, K; Valsala Gopalakrishnan, A; Vellingiri, B	1
Aghsami, M; Bodaghi-Namileh, V; Kasirzadeh, S; Omidi, A; Sabzevari, O; Sepand, MR; Seyednejad, SA	1
Hu, Y; Huang, X; Liang, B; Wang, L; Yao, M; Yu, C; Zhang, A; Zhang, B	1
Bavithra Jothi, G; Hema, T; Miltonprabu, S; Nandhini, V; Ramesh, M; Thangapandiyan, S; Uddin, MS	1
Hu, J; Jin, J; Lo-Coco, F; Zhu, HH	1
Alidadi, H; Kalantari, H; Khodayar, MJ; Khorsandi, L; Saki, N; Samimi, A; Teymoori, A	1
Gonsebatt, ME; Valdovinos-Flores, C	1
Miltonprabu, S; Muthumani, M	1
Ding, L; Feng, G; Li, S; Liu, J; Niu, M; Niu, Q; Wen, H; Xiao, J; Xu, S	1
Das Saha, K; Das, S; Nath, D; Pradhan, GK	1
Do, JT; Ha, WT; Heo, YT; Jalaludeen, AM; Kim, JH; Lee, R; Lee, WY; Park, C; Song, H	1
Kumar, V; Prakash, C	1
Chan, EC; Gong, Z; Lam, SH; Li, C; Li, P; Tan, YM	1
Cheng, ML	1
Ananthi, S; Chandronitha, C; Gayathri, V; Lakshmisundaram, R; Ramakrishnan, G; Vasanthi, HR	1
Bozhkov, AI; Flora, SJ; Jain, A; Padalko, VI; Yadav, A	1
Abdennour, C; Boulakoud, MS; Boumendjel, A; Bouzerna, N; El Feki, A; Klibet, F; Messarah, M	1
Dai, Y; Li, W; Li, X; Liu, F; Niu, N; Pan, X; Yu, Z; Zhao, Y	1
Hernández, A; Marcos, R; Sampayo-Reyes, A	1
Choudhury, M; Das, AS; Ghosh, A; Karmakar, S; Maiti, A; Majumdar, S; Mitra, C	1
Mohamed Jalaludeen, A; Pari, L	1
Khan, S; Kumar, A; Leo, MD; Majhi, CR; Prawez, S; Sankar, P; Sarkar, SN; Telang, AG	1
Muthumani, M; Prabu, SM	1
Das, J; Roy, A; Sil, PC	1
Andrzejak, R; Antonowicz-Juchniewicz, J; Szymańska-Chabowska, A	1
HUNT, AH; PARR, RM; TAYLOR, DM; TROTT, NG	1
SANDERSON, KV	1
PELNER, L; WALDMAN, S	1
Flora, SJ; Gupta, R	2
Biswas, A; Chowdhury, A; Dhali, GK; Ghatak, S; Santra, A	1
Kumar, M; Sharma, A; Sharma, MK	1
Gao, Y; Han, G; Li, GX; Liu, KM; Nie, JS; Pei, QL; Qiu, YL; Zhang, WP	1
Datta, DV; Narang, AP	1
Hisanaga, A; Ishinishi, N; Tomita, M	1
Hochadel, JF; Waalkes, MP	1
Achanzar, W; Goyer, RA; Liu, J; Liu, Y; Waalkes, MP	1
Guha Mazumder, DN	1
Hine, CH; Nelson, KW; Pinto, SS	1
Malchow, H; Schmeisser, W	1
Gerber, MA; Popper, H; Schaffner, F; Selikoff, IJ	1
Sorensen, EM	1
Browder, AA; Joselow, MM; Louria, DB	1
Knoth, W	1
Kobylinski, S	1

Reviews

15 review(s) available for arsenic and Acute Liver Injury, Drug-Induced

Article	Year
Insights into the All-trans-Retinoic Acid and Arsenic Trioxide Combination Treatment for Acute Promyelocytic Leukemia: A Meta-Analysis. Acta haematologica, 2015, Volume: 134, Issue:2 Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Chemical and Drug Induced Liver Injury; Controlled Clinical Trials as Topic; Humans; Leukemia, Promyelocytic, Acute; Oxides; Randomized Controlled Trials as Topic; Remission Induction; Risk; Tretinoin	2015
[MEDICAMENTOUS CHOLOSTATIC HEPATITIS]. Revue internationale d'hepatologie, 1964, Volume: 14 Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Antimetabolites; Antithyroid Agents; Antitubercular Agents; Arsenicals; Chemical and Drug Induced Liver Injury; Hepatitis; Hormones; Hypoglycemic Agents; Iatrogenic Disease; Pathology; Research; Sulfanilamide; Sulfanilamides; Sulfonamides; Toxicology; Tranquilizing Agents	1964
Toxicity of inorganic arsenic salts. Adverse drug reactions and acute poisoning reviews, 1984,Autumn, Volume: 3, Issue:3 Topics: Acute Disease; Arsenic; Arsenic Poisoning; Arsenicals; Biotransformation; Carcinogens; Central Nervous System Diseases; Chemical and Drug Induced Liver Injury; Chemistry; Chronic Disease; Digestive System; Hematologic Diseases; Hemodynamics; History, 18th Century; History, 19th Century; History, 20th Century; History, Ancient; Humans; Intestinal Absorption; Kidney Diseases; Mutagens; Nervous System Diseases; Skin Diseases; Teratogens; Tissue Distribution	1984
[The liver and arsenic]. Gastroenterologie clinique et biologique, 1982, Volume: 6, Issue:11 Topics: Animals; Arsenic; Arsenic Poisoning; Arsenicals; Chemical and Drug Induced Liver Injury; Hemangiosarcoma; Humans; Hypertension, Portal; Liver; Liver Cirrhosis; Liver Diseases; Liver Neoplasms	1982
Arsenic trioxide therapy for relapsed acute promyelocytic leukemia: an useful salvage therapy. Leukemia & lymphoma, 2000, Volume: 38, Issue:3-4 Topics: Acute Kidney Injury; Antineoplastic Agents; Apoptosis; Arrhythmias, Cardiac; Arsenic Trioxide; Arsenicals; Cell Differentiation; Chemical and Drug Induced Liver Injury; Drug Evaluation; Drug Screening Assays, Antitumor; Gastrointestinal Neoplasms; Humans; Leukemia, Promyelocytic, Acute; Life Tables; Medicine, Chinese Traditional; Mitochondria; Models, Biological; Neoplasm Proteins; Neoplastic Stem Cells; Neuromuscular Diseases; Oncogene Proteins, Fusion; Oxides; Remission Induction; Salvage Therapy; Survival Analysis; Treatment Outcome; Tumor Cells, Cultured; Urinary Bladder Neoplasms	2000
[Liver damage due to drugs. I]. La Clinica terapeutica, 1974, Jan-15, Volume: 68, Issue:1 Topics: Arsenicals; Chemical and Drug Induced Liver Injury; Chloramphenicol; Cholestasis; Coumarins; Drug-Related Side Effects and Adverse Reactions; Erythromycin; Halothane; Humans; Imipramine; Liver; Methotrexate; Methyldopa; Nicotinic Acids; Oxacillin; Phenylbutazone; Testosterone; Tetracycline	1974
[Liver diseases induced by drugs]. Revista clinica espanola, 1967, Aug-15, Volume: 106, Issue:3 Topics: Animals; Arsenicals; Chemical and Drug Induced Liver Injury; Chloroform; Chlorpromazine; Contraceptives, Oral; Drug Hypersensitivity; Humans; Isoniazid; Liver Diseases; Steroids; Tannins; Tetracycline	1967
An appraisal on molecular and biochemical signalling cascades during arsenic-induced hepatotoxicity. Life sciences, 2020, Nov-01, Volume: 260 Topics: Animals; Antioxidants; Apoptosis; Arsenic; Arsenic Poisoning; Chemical and Drug Induced Liver Injury; Female; Humans; Liver Cirrhosis; Mitochondria, Liver; NF-kappa B; Oxidative Stress; Pregnancy; Prenatal Exposure Delayed Effects; Signal Transduction	2020
Molecular mechanism of heavy metals (Lead, Chromium, Arsenic, Mercury, Nickel and Cadmium) - induced hepatotoxicity - A review. Chemosphere, 2021, Volume: 271 Topics: Arsenic; Cadmium; Chemical and Drug Induced Liver Injury; Chromium; Humans; Lead; Mercury; Metals, Heavy; Nickel	2021
The simpler, the better: oral arsenic for acute promyelocytic leukemia. Blood, 2019, 08-15, Volume: 134, Issue:7 Topics: Administration, Oral; Antineoplastic Agents; Arsenic; Arsenic Trioxide; Chemical and Drug Induced Liver Injury; China; Diarrhea; Humans; Leukemia, Promyelocytic, Acute; Leukocytosis	2019
Mechanism of the protective action of taurine in toxin and drug induced organ pathophysiology and diabetic complications: a review. Food & function, 2012, Volume: 3, Issue:12 Topics: Animals; Antioxidants; Arsenic; Blood Pressure; Cadmium; Calcium; Chemical and Drug Induced Liver Injury; Cytokines; Cytoprotection; Diabetes Complications; Fluorides; Hazardous Substances; Heart Diseases; Humans; Kidney Diseases; Nervous System Diseases; Neurotransmitter Agents; Taurine; Water-Electrolyte Balance	2012
Some aspects of arsenic toxicity and carcinogenicity in living organism with special regard to its influence on cardiovascular system, blood and bone marrow. International journal of occupational medicine and environmental health, 2002, Volume: 15, Issue:2 Topics: Anemia; Arsenic; Bone Marrow; Cardiovascular Diseases; Chemical and Drug Induced Liver Injury; Environmental Exposure; Humans; Neoplasms; Water Pollutants, Chemical	2002
[Occupational liver lesions]. Medizinische Klinik, 1977, Nov-11, Volume: 72, Issue:45 Topics: Arsenic; Cadmium; Chemical and Drug Induced Liver Injury; Chromium; Fatty Liver; Humans; Liver Cirrhosis; Liver Neoplasms; Occupational Diseases; Paraquat; Time Factors; Vinyl Chloride	1977
Environmental hepatic injury in man. Progress in liver diseases, 1979, Volume: 6 Topics: Adolescent; Adult; Aged; Animals; Arsenic; Carcinogens; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Drug-Related Side Effects and Adverse Reactions; Environmental Pollutants; Female; Hemangiosarcoma; Humans; Infant; Infant, Newborn; Liver Neoplasms; Male; Middle Aged; Necrosis; Pharmacology; Thorium Dioxide; Vinyl Chloride	1979
The human toxicity of certain trace elements. Annals of internal medicine, 1972, Volume: 76, Issue:2 Topics: Arsenic; Cadmium; Central Nervous System Diseases; Chemical and Drug Induced Liver Injury; Cobalt; Copper; Gastrointestinal Diseases; Heart Diseases; Humans; Liver; Lung Diseases; Manganese Poisoning; Molybdenum; Nickel; Occupational Medicine; Selenium; Tellurium; Tin; Trace Elements; Vanadium; Zinc	1972

Trials

4 trial(s) available for arsenic and Acute Liver Injury, Drug-Induced

Article	Year
Phase 2 study of the efficacy and safety of the combination of arsenic trioxide, interferon alpha, and zidovudine in newly diagnosed chronic adult T-cell leukemia/lymphoma (ATL). Blood, 2009, Jun-25, Volume: 113, Issue:26 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Chemical and Drug Induced Liver Injury; Drug Eruptions; Drug Synergism; Female; Gastrointestinal Diseases; Hematologic Diseases; Human T-lymphotropic virus 1; Humans; Interferon-alpha; Leukemia-Lymphoma, Adult T-Cell; Male; Middle Aged; Oxides; Proviruses; Remission Induction; Viral Load; Zidovudine	2009
The addition of arsenic trioxide to low-dose Ara-C in older patients with AML does not improve outcome. Leukemia, 2011, Volume: 25, Issue:7 Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Chemical and Drug Induced Liver Injury; Comorbidity; Cytarabine; Disease-Free Survival; Early Termination of Clinical Trials; Female; Gastrointestinal Diseases; Heart Diseases; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Male; Middle Aged; Oxides; Remission Induction; Treatment Outcome	2011
Hepatotoxicity profile of single agent arsenic trioxide in the treatment of newly diagnosed acute promyelocytic leukemia, its impact on clinical outcome and the effect of genetic polymorphisms on the incidence of hepatotoxicity. Leukemia, 2006, Volume: 20, Issue:5 Topics: Adult; Arsenic Trioxide; Arsenicals; Chemical and Drug Induced Liver Injury; Cohort Studies; Disease-Free Survival; Female; Follow-Up Studies; Genetic Predisposition to Disease; Humans; Incidence; Leukemia, Promyelocytic, Acute; Liver; Liver Function Tests; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxides; Polymorphism, Genetic; Remission Induction; Risk Factors; Survival Rate; Treatment Outcome	2006
[Arsenic trioxide for the treatment of medium and advanced primary liver cancer]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2002, Volume: 10, Issue:1 Topics: Adult; Aged; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Chemical and Drug Induced Liver Injury; Female; Humans; Liver Neoplasms; Male; Middle Aged; Oxides; Remission Induction; Treatment Outcome; Vomiting	2002

Other Studies

77 other study(ies) available for arsenic and Acute Liver Injury, Drug-Induced

Article	Year
Sub-chronic exposure to realgar induces liver injury via upregulating the TXNIP/NLRP3 pathway and disturbing bile acid homeostasis in mice. Journal of ethnopharmacology, 2021, Dec-05, Volume: 281 Topics: Animals; Arsenicals; Bile Acids and Salts; Carrier Proteins; Chemical and Drug Induced Liver Injury; Gene Expression Regulation; Homeostasis; Male; Mice; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Signal Transduction; Sulfides; Thioredoxins; Up-Regulation	2021
Liver metabonomics study on the protective effect of glycyrrhetinic acid against realgar-induced liver injury. Chinese journal of natural medicines, 2020, Volume: 18, Issue:2 Topics: Animals; Arsenicals; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Glycyrrhetinic Acid; Male; Mass Spectrometry; Metabolomics; Mice; Sulfides	2020
Plasma metabolomics study of the hepatoprotective effect of glycyrrhetinic acid on realgar-induced sub-chronic hepatotoxicity in mice via Journal of ethnopharmacology, 2017, Aug-17, Volume: 208 Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Arsenicals; Aspartate Aminotransferases; Catalase; Chemical and Drug Induced Liver Injury; Glutathione; Glutathione Peroxidase; Glycyrrhetinic Acid; Hepatocytes; Lipid Metabolism; Liver; Male; Metabolomics; Mice, Inbred ICR; Protective Agents; Proton Magnetic Resonance Spectroscopy; Serum Albumin; Sulfides; Superoxide Dismutase	2017
Metformin ameliorates arsenic trioxide hepatotoxicity via inhibiting mitochondrial complex I. Cell death & disease, 2017, 11-02, Volume: 8, Issue:11 Topics: Animals; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Line; Chemical and Drug Induced Liver Injury; Electron Transport Complex I; Glucose; Glycolysis; Humans; Leukemia, Myeloid; Male; Metformin; Mice; NAD; Oxidative Phosphorylation; Oxides; Reactive Oxygen Species; Rotenone	2017
Clinical outcomes, histopathological patterns, and chemical analysis of Ayurveda and herbal medicine associated with severe liver injury-A single-center experience from southern India. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2018, Volume: 37, Issue:1 Topics: Adult; Arsenicals; Chemical and Drug Induced Liver Injury; Drugs, Chinese Herbal; Female; Follow-Up Studies; Herbal Medicine; Humans; Liver; Male; Medicine, Ayurvedic; Mercury Compounds; Middle Aged; Risk; Severity of Illness Index; Time Factors; Volatile Organic Compounds	2018
Hepatic histopathological changes and dysfunction in primates following exposure to organic arsenic diphenylarsinic acid. The Journal of toxicological sciences, 2018, Volume: 43, Issue:5 Topics: Alanine Transaminase; Animals; Arsenicals; Aspartate Aminotransferases; Biomarkers; Chemical and Drug Induced Liver Injury; Child; Female; Humans; Lipid Droplets; Liver; Liver Diseases; Macaca fascicularis; Time Factors	2018
Realgar and cinnabar are essential components contributing to neuroprotection of Angong Niuhuang Wan with no hepatorenal toxicity in transient ischemic brain injury. Toxicology and applied pharmacology, 2019, 08-15, Volume: 377 Topics: Animals; Arsenic; Arsenicals; Biological Products; Chemical and Drug Induced Liver Injury; Free Radical Scavengers; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Kidney Diseases; Male; Medicine, Chinese Traditional; Mercury; Mercury Compounds; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sulfides	2019
TRIM21 Ubiquitylates SQSTM1/p62 and Suppresses Protein Sequestration to Regulate Redox Homeostasis. Molecular cell, 2016, Mar-03, Volume: 61, Issue:5 Topics: Adaptor Proteins, Signal Transducing; Animals; Arsenic Trioxide; Arsenicals; Cell Death; Chemical and Drug Induced Liver Injury; Cytoskeletal Proteins; Disease Models, Animal; Heart Failure; Heat-Shock Proteins; HEK293 Cells; Homeostasis; Humans; Intracellular Signaling Peptides and Proteins; Kelch-Like ECH-Associated Protein 1; Liver; Lysine; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Oxidation-Reduction; Oxidative Stress; Oxides; Protein Binding; Protein Interaction Domains and Motifs; Protein Multimerization; Ribonucleoproteins; RNA Interference; Sequestosome-1 Protein; Signal Transduction; Time Factors; Transfection; Ubiquitination	2016
Journal of ethnopharmacology, 2016, Nov-04, Volume: 192 Topics: Animals; Arsenicals; Biomarkers; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Liver; Male; Metabolomics; Mice, Inbred ICR; Multivariate Analysis; Principal Component Analysis; Proton Magnetic Resonance Spectroscopy; Sulfides; Time Factors; Toxicity Tests, Subchronic	2016
Protective effects of oxymatrine against arsenic trioxide-induced liver injury. Oncotarget, 2017, Feb-21, Volume: 8, Issue:8 Topics: Alkaloids; Animals; Antioxidants; Arsenic Trioxide; Arsenicals; Blotting, Western; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Heme Oxygenase-1; Male; NF-E2-Related Factor 2; Oxidative Stress; Oxides; Quinolizines; Rats; Rats, Wistar; Signal Transduction	2017
Melatonin protects against arsenic trioxide-induced liver injury by the upregulation of Nrf2 expression through the activation of PI3K/AKT pathway. Oncotarget, 2017, Jan-17, Volume: 8, Issue:3 Topics: Animals; Arsenic Trioxide; Arsenicals; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Gene Expression Regulation; Injections, Intraperitoneal; Liver; Male; Melatonin; NF-E2-Related Factor 2; Oxidative Stress; Oxides; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction; Up-Regulation	2017
Mitigation of hepatotoxic effects of arsenic trioxide through omega-3 fatty acid in rats. Toxicology and industrial health, 2014, Volume: 30, Issue:9 Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Antioxidants; Arsenic Trioxide; Arsenicals; Aspartate Aminotransferases; Body Weight; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Fatty Acids, Omega-3; Glutathione; L-Lactate Dehydrogenase; Lipid Peroxidation; Liver; Male; Oxides; Rats; Rats, Wistar	2014
INTRAHEPATIC CHOLESTASIS VS. POSTHEPATIC JAUNDICE: METHODS OF DIAGNOSIS, WITH A NOTE ON HYPERCHOLESTEREMIC XANTHOMATOSIS IN A PATIENT WITH CHLORPROMAZINE CHOLESTASIS. The Medical clinics of North America, 1964, Volume: 48 Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Alkaline Phosphatase; Androgens; Anti-Bacterial Agents; Antithyroid Agents; Arsenicals; Biopsy; Chemical and Drug Induced Liver Injury; Chlorpromazine; Cholestasis; Cholestasis, Intrahepatic; Diagnosis; Geriatrics; Hepatitis; Humans; Hypercholesterolemia; Jaundice; Jaundice, Obstructive; Liver Diseases; Phenothiazines; Radiography; Toxicology; Xanthomatosis	1964
Estrogen signaling in livers of male mice with hepatocellular carcinoma induced by exposure to arsenic in utero. Journal of the National Cancer Institute, 2004, Mar-17, Volume: 96, Issue:6 Topics: Animals; Arsenicals; Aryl Hydrocarbon Hydroxylases; Carcinogens; Chemical and Drug Induced Liver Injury; Cyclin D1; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Cytochrome P450 Family 7; DNA Methylation; Environmental Exposure; Estrogen Receptor alpha; Estrogens; Fetus; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Liver; Liver Diseases; Liver Neoplasms, Experimental; Male; Mice; Receptors, Estrogen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Steroid Hydroxylases	2004
Auditory neurotoxicity and hepatotoxicity after MSMA (monosodium methanarsenate) high dose oral intake. Clinical toxicology (Philadelphia, Pa.), 2005, Volume: 43, Issue:4 Topics: Adult; Antidotes; Arsenic; Arsenic Poisoning; Arsenicals; Audiometry; Bilirubin; Chemical and Drug Induced Liver Injury; Evoked Potentials, Auditory, Brain Stem; Hearing Loss, Sensorineural; Hemodynamics; Humans; Liver; Liver Function Tests; Male; Neurotoxicity Syndromes; Suicide, Attempted	2005
[Jaundices of therapeutic origin]. Minerva medica, 1967, Oct-13, Volume: 58, Issue:82 Topics: Antineoplastic Agents; Antitubercular Agents; Arsenicals; Chemical and Drug Induced Liver Injury; Chlorpromazine; Contraceptives, Oral; Drug Hypersensitivity; Halothane; Hepatitis B; Humans; Hypoglycemic Agents; Iatrogenic Disease; Jaundice; Monoamine Oxidase Inhibitors	1967
Efficacy of dimercapto chelating agents for the treatment of poisoning by percutaneously applied dichloro(2-chlorovinyl)arsine in rabbits. Human & experimental toxicology, 1993, Volume: 12, Issue:3 Topics: Administration, Topical; Animals; Arsenic Poisoning; Arsenicals; Chelating Agents; Chemical and Drug Induced Liver Injury; Dimercaprol; Gallbladder; Lethal Dose 50; Liver; Lung; Male; Rabbits; Succimer; Sulfhydryl Compounds; Unithiol	1993
Acute arsine intoxication as a consequence of metal burnishing operations. American journal of industrial medicine, 1997, Volume: 32, Issue:3 Topics: Adult; Air Pollutants, Occupational; Arsenic Poisoning; Arsenicals; Chemical and Drug Induced Liver Injury; Chromatography, Liquid; Exchange Transfusion, Whole Blood; Hemolysis; Humans; Kidney Diseases; Lung Diseases; Male; Mass Spectrometry; Metallurgy; Occupational Exposure; Poisoning	1997
Selenium effects on gallium arsenide induced biochemical and immunotoxicological changes in rats. Chemico-biological interactions, 1999, Aug-30, Volume: 122, Issue:1 Topics: Animals; Arsenic Poisoning; Arsenicals; Body Weight; Chemical and Drug Induced Liver Injury; Gallium; Hematopoiesis; Immunotoxins; Injections, Intraperitoneal; Male; Organ Size; Rats; Rats, Wistar; Selenium	1999
Efficacy of a potentized homoeopathic drug (Arsenicum-album-30) in reducing cytotoxic effects produced by arsenic trioxide in mice: III. Enzymatic changes and recovery of tissue damage in liver. Complementary therapies in medicine, 2000, Volume: 8, Issue:2 Topics: Animals; Arsenic Poisoning; Arsenic Trioxide; Arsenicals; Chemical and Drug Induced Liver Injury; Liver Diseases; Materia Medica; Mice; Oxides	2000
Meso 2,3-dimercaptosuccinic acid (DMSA) and monoisoamyl DMSA effect on gallium arsenide induced pathological liver injury in rats. Toxicology letters, 2002, Jun-07, Volume: 132, Issue:1 Topics: Alanine Transaminase; Animals; Arsenicals; Aspartate Aminotransferases; Catalase; Chelating Agents; Chemical and Drug Induced Liver Injury; Gallium; Glutathione; Glutathione Peroxidase; Lipid Peroxidation; Liver Function Tests; Male; Metals; Oxidation-Reduction; Oxidative Stress; Porphobilinogen Synthase; Rats; Succimer; Superoxide Dismutase	2002
Arsine toxicity aboard the Asiafreighter. British medical journal, 1975, Sep-06, Volume: 3, Issue:5983 Topics: Acute Kidney Injury; Adult; Arsenic Poisoning; Arsenicals; Bone Marrow Examination; Chemical and Drug Induced Liver Injury; Creatinine; Dexamethasone; Diarrhea; Environmental Exposure; Exchange Transfusion, Whole Blood; Fever; Gas Poisoning; Hair; Hemoglobinuria; Hemolysis; Humans; Liver; Male; Middle Aged; Nausea; Naval Medicine; Paresthesia; Peripheral Nervous System Diseases; Thrombocytopenia; Time Factors; Urea; Vomiting	1975
Vinyl chloride-associated liver disease. Annals of internal medicine, 1976, Volume: 84, Issue:6 Topics: Adult; Animals; Arsenicals; Chemical and Drug Induced Liver Injury; Epidemiologic Methods; Hemangiosarcoma; Humans; Liver Cirrhosis; Liver Diseases; Liver Function Tests; Liver Neoplasms; Male; Occupational Diseases; Polymers; Radionuclide Imaging; Rats; Thorium Dioxide; Time Factors; Vinyl Chloride; Vinyl Compounds	1976
Noncirrhotic presinusoidal portal hypertension associated with chronic arsenical intoxication. Gastroenterology, 1975, Volume: 68, Issue:5 Pt 1 Topics: Adult; Arsenic Poisoning; Arsenicals; Biopsy, Needle; Chemical and Drug Induced Liver Injury; Chronic Disease; Dilatation; Esophageal and Gastric Varices; Humans; Hypertension, Portal; Liver; Male; Portal Vein; Psoriasis; Radiography; Splenic Vein	1975
[Diphetarsone-induced hepatitis. A second case]. Presse medicale (Paris, France : 1983), 1992, Jun-06, Volume: 21, Issue:21 Topics: Aged; Animals; Antiprotozoal Agents; Arsenicals; Chemical and Drug Induced Liver Injury; Cholestasis; Entamoeba; Entamoebiasis; Female; Humans	1992
[Prolonged hepatitis after ingestion of diphetarsone]. Gastroenterologie clinique et biologique, 1988, Volume: 12, Issue:2 Topics: Adult; Antiprotozoal Agents; Arsenicals; Chemical and Drug Induced Liver Injury; Humans; Male	1988
Liver biopsy in psoriatics previously treated with potassium arsenite. A controlled study. Acta dermato-venereologica, 1974, Volume: 54, Issue:3 Topics: Arsenicals; Biopsy; Chemical and Drug Induced Liver Injury; Humans; Liver; Liver Diseases; Liver Neoplasms; Male; Microscopy, Electron; Psoriasis	1974
Hepatic excretion and storage of sulfobromophthalein sodium in experimental hepatic necrosis in the dog. The Cornell veterinarian, 1973, Volume: 63, Issue:3 Topics: Aflatoxins; Alanine Transaminase; Animals; Arsenicals; Aspartate Aminotransferases; Benzamides; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Common Bile Duct; Dog Diseases; Dogs; Injections, Intravenous; Ligation; Liver; Liver Diseases; Liver Function Tests; Necrosis; Plasma Volume; Sodium; Sulfides; Sulfobromophthalein	1973
[Hepatotoxicity of therapeutic drugs]. Revue medicale de Liege, 1967, Mar-01, Volume: 22, Issue:5 Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Antitubercular Agents; Arsenicals; Chemical and Drug Induced Liver Injury; Drug-Related Side Effects and Adverse Reactions; Hormones; Humans; Monoamine Oxidase Inhibitors; Sulfonamides	1967
Toxic hepatopathy. The American journal of gastroenterology, 1968, Volume: 49, Issue:1 Topics: Aminosalicylic Acids; Anabolic Agents; Animals; Anti-Bacterial Agents; Antineoplastic Agents; Arsenicals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chlorpromazine; Drug Hypersensitivity; Humans; Iproniazid; Rats	1968
Potential protective role of curcumin powder to regulate arsenic-induced hepatorenal toxicity and hyperlipidemic metabolic dysfunction in rat model. Pakistan journal of pharmaceutical sciences, 2021, Volume: 34, Issue:4(Suppleme Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arsenic; Chemical and Drug Induced Liver Injury; Curcumin; Hyperlipidemias; Kidney Diseases; Rats	2021
Lentinan alleviates arsenic-induced hepatotoxicity in mice via downregulation of OX40/IL-17A and activation of Nrf2 signaling. BMC pharmacology & toxicology, 2022, 03-22, Volume: 23, Issue:1 Topics: Animals; Arsenic; Chemical and Drug Induced Liver Injury; Down-Regulation; Interleukin-17; Lentinan; Mice; NF-E2-Related Factor 2; NLR Family, Pyrin Domain-Containing 3 Protein	2022
Combined effect of arsenic and polystyrene-nanoplastics at environmentally relevant concentrations in mice liver: Activation of apoptosis, pyroptosis and excessive autophagy. Chemosphere, 2022, Volume: 300 Topics: Animals; Apoptosis; Arsenic; Autophagy; Caspase 3; Chemical and Drug Induced Liver Injury; Mammals; Mice; Microplastics; NLR Family, Pyrin Domain-Containing 3 Protein; Polystyrenes; Pyroptosis	2022
Citicoline ameliorates arsenic-induced hepatotoxicity and diabetes in mice by overexpression of VAMP2, PPAR-γ, As3MT, and SIRT3. Pesticide biochemistry and physiology, 2023, Volume: 192 Topics: Animals; Antioxidants; Arsenic; Chemical and Drug Induced Liver Injury; Cytidine Diphosphate Choline; Diabetes Mellitus; Glucose Intolerance; Insulins; Methyltransferases; Mice; Oxidative Stress; PPAR gamma; Sirtuin 3; Vesicle-Associated Membrane Protein 2	2023
Integrated metabolomics and network pharmacology revealing the mechanism of arsenic-induced hepatotoxicity in mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2023, Volume: 178 Topics: Animals; Arsenic; Chemical and Drug Induced Liver Injury; Drugs, Chinese Herbal; Humans; Metabolomics; Mice; Network Pharmacology; Niacinamide; Phosphatidylinositol 3-Kinases	2023
Hepatoprotective and anti-hyperglycemic effects of ferulic acid in arsenic-exposed mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2023, Volume: 178 Topics: Animals; Antioxidants; Arsenic; Chemical and Drug Induced Liver Injury; Glucose Intolerance; Hypoglycemic Agents; Liver; Mice; Oxidative Stress; Peroxisome Proliferator-Activated Receptors	2023
Protective efficacy of thymoquinone or ebselen separately against arsenic-induced hepatotoxicity in rat. Environmental science and pollution research international, 2021, Volume: 28, Issue:5 Topics: Animals; Antioxidants; Arsenic; Azoles; Benzoquinones; Chemical and Drug Induced Liver Injury; Female; Isoindoles; Liver; Organoselenium Compounds; Oxidative Stress; Rats	2021
Semaphorin 4A antibody alleviates arsenic-induced hepatotoxicity in mice via inhibition of AKT2/NF-κB inflammatory signaling. Toxicology and applied pharmacology, 2021, 01-01, Volume: 410 Topics: Animals; Arsenic; Autoantibodies; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Inflammation Mediators; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Proto-Oncogene Proteins c-akt; Semaphorins	2021
Associations between and risks of trace elements related to skin and liver damage induced by arsenic from coal burning. Ecotoxicology and environmental safety, 2021, Jan-15, Volume: 208 Topics: Adult; Arsenic; Arsenic Poisoning; Biomarkers; Chemical and Drug Induced Liver Injury; China; Coal; Female; Hair; Humans; Male; Middle Aged; Risk Factors; Skin Diseases; Trace Elements	2021
Acetyl-l-carnitine attenuates arsenic-induced liver injury by abrogation of mitochondrial dysfunction, inflammation, and apoptosis in rats. Environmental toxicology and pharmacology, 2018, Volume: 58 Topics: Acetylcarnitine; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Arsenic; Caspase 3; Caspase 9; Catalase; Chemical and Drug Induced Liver Injury; Cytochromes c; Glutathione; Interleukin-1beta; Interleukin-6; Liver; Male; Malondialdehyde; Mitochondria; Oxidative Stress; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase; Transcription Factor RelA	2018
The PKCδ-Nrf2-ARE signalling pathway may be involved in oxidative stress in arsenic-induced liver damage in rats. Environmental toxicology and pharmacology, 2018, Volume: 62 Topics: Animals; Antioxidant Response Elements; Arsenic; Arsenic Poisoning; Chemical and Drug Induced Liver Injury; Female; Male; NF-E2-Related Factor 2; Oxidative Stress; Protein Kinase C-delta; Rats, Wistar; Signal Transduction	2018
Sulforaphane Potentially Ameliorates Arsenic Induced Hepatotoxicity in Albino Wistar Rats: Implication of PI3K/Akt/Nrf2 Signaling Pathway. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2019, Volume: 52, Issue:5 Topics: Animals; Arsenic; Chemical and Drug Induced Liver Injury; Isothiocyanates; Liver; Male; NF-E2-Related Factor 2; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Signal Transduction; Sulfoxides	2019
Microarray analysis of apoptosis gene expression in liver injury induced by chronic exposure to arsenic and high-fat diet in male mice. Environmental science and pollution research international, 2019, Volume: 26, Issue:25 Topics: Animals; Apoptosis; Arsenic; Caspase 8; Chemical and Drug Induced Liver Injury; Diet, High-Fat; Gene Expression Profiling; Liver; Male; Mice; Oligonucleotide Array Sequence Analysis; Oxidative Stress	2019
Nerve growth factor exhibits an antioxidant and an autocrine activity in mouse liver that is modulated by buthionine sulfoximine, arsenic, and acetaminophen. Free radical research, 2013, Volume: 47, Issue:5 Topics: Acetaminophen; Animals; Antioxidants; Arsenic; Autocrine Communication; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Gene Expression Regulation; Liver; Mice; Nerve Growth Factor; Neurons; Oxidation-Reduction; Oxidative Stress; PC12 Cells; Phosphorylation; Rats; Receptor, trkA	2013
Ameliorative efficacy of tetrahydrocurcumin against arsenic induced oxidative damage, dyslipidemia and hepatic mitochondrial toxicity in rats. Chemico-biological interactions, 2015, Jun-25, Volume: 235 Topics: Alanine Transaminase; Animals; Antioxidants; Arsenic; Arsenic Poisoning; Aspartate Aminotransferases; Catalase; Chemical and Drug Induced Liver Injury; Curcumin; Dyslipidemias; Glutathione; Glutathione Peroxidase; Liver; Male; Mitochondria; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances	2015
[Preventive effects of lutein on liver toxicity in mice induced by arsenic]. Wei sheng yan jiu = Journal of hygiene research, 2015, Volume: 44, Issue:4 Topics: Animals; Antioxidants; Arsenic; Arsenites; Chemical and Drug Induced Liver Injury; Liver; Lutein; Mice	2015
Enhanced protective activity of nano formulated andrographolide against arsenic induced liver damage. Chemico-biological interactions, 2015, Dec-05, Volume: 242 Topics: Animals; Antioxidants; Arsenic; Chemical and Drug Induced Liver Injury; Chemistry, Pharmaceutical; Cytoprotection; Diterpenes; Lactic Acid; Mice; Nanocapsules; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer	2015
Biochanin A Ameliorates Arsenic-Induced Hepato- and Hematotoxicity in Rats. Molecules (Basel, Switzerland), 2016, Jan-09, Volume: 21, Issue:1 Topics: Animals; Antioxidants; Arsenic; Blood Cell Count; Body Weight; Catalase; Chemical and Drug Induced Liver Injury; Drinking; Eating; Erythrocyte Indices; Genistein; Glutathione; Lipid Peroxidation; Liver; Male; Protective Agents; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Selenium; Superoxide Dismutase	2016
Chronic Arsenic Exposure-Induced Oxidative Stress is Mediated by Decreased Mitochondrial Biogenesis in Rat Liver. Biological trace element research, 2016, Volume: 173, Issue:1 Topics: Animals; Arsenic; Chemical and Drug Induced Liver Injury; Liver; Male; Mitochondria, Liver; Mitochondrial Dynamics; Oxidative Stress; Rats; Rats, Wistar	2016
Metabolomic Characterizations of Liver Injury Caused by Acute Arsenic Toxicity in Zebrafish. PloS one, 2016, Volume: 11, Issue:3 Topics: Alanine Transaminase; Animals; Arsenic; Bile Acids and Salts; Bilirubin; Biomarkers; Chemical and Drug Induced Liver Injury; Cholic Acid; Cluster Analysis; Energy Metabolism; Gas Chromatography-Mass Spectrometry; Glycolysis; Glycylglycine; Liver; Metabolome; Principal Component Analysis; Taurine; Zebrafish	2016
[Pay attention to the hepatopathy which was caused by environment arsenic]. Zhonghua yi xue za zhi, 2009, Jun-02, Volume: 89, Issue:21 Topics: Arsenic; Arsenic Poisoning; Chemical and Drug Induced Liver Injury; Environmental Pollutants; Humans	2009
Protective role of tannin-rich fraction of Camellia sinensis in tissue arsenic burden in Sprague Dawley rats. Human & experimental toxicology, 2010, Volume: 29, Issue:9 Topics: Animals; Arsenic; Arsenic Poisoning; Arsenites; Biomarkers; Camellia sinensis; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Female; Kidney; Liver; Oxidative Stress; Phytotherapy; Plant Extracts; Plant Leaves; Porphobilinogen Synthase; Protective Agents; Random Allocation; Rats; Rats, Sprague-Dawley; Renal Insufficiency; Sodium Compounds; Tannins	2010
Therapeutic efficacy of silymarin and naringenin in reducing arsenic-induced hepatic damage in young rats. Ecotoxicology and environmental safety, 2011, Volume: 74, Issue:4 Topics: Animals; Antioxidants; Arsenic; Arsenic Poisoning; Arsenites; Catalase; Chelating Agents; Chemical and Drug Induced Liver Injury; Environmental Pollutants; Flavanones; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Lipid Peroxidation; Liver; Male; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Silymarin; Sodium Compounds; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances	2011
Hepatoprotective role and antioxidant capacity of selenium on arsenic-induced liver injury in rats. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2012, Volume: 64, Issue:3 Topics: Animals; Antioxidants; Arsenic; Arsenites; Chemical and Drug Induced Liver Injury; Male; Oxidative Stress; Rats; Rats, Wistar; Selenium; Sodium Compounds; Sodium Selenite	2012
Inhibition of arsenic-induced rat liver injury by grape seed exact through suppression of NADPH oxidase and TGF-β/Smad activation. Toxicology and applied pharmacology, 2011, Aug-01, Volume: 254, Issue:3 Topics: Animals; Arsenic; Cells, Cultured; Chemical and Drug Induced Liver Injury; Grape Seed Extract; Humans; Liver Cirrhosis; Male; NADPH Oxidases; Rats; Rats, Sprague-Dawley; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta	2011
Identification of differentially expressed genes in the livers of chronically i-As-treated hamsters. Mutation research, 2011, Aug-01, Volume: 713, Issue:1-2 Topics: Animals; Arsenic; Body Weight; Carcinogens; Chemical and Drug Induced Liver Injury; Cricetinae; Drinking; Eating; Gene Expression Profiling; Liver; Mesocricetus; Mutagens	2011
Arsenic-induced hepatic mitochondrial toxicity in rats and its amelioration by dietary phosphate. Environmental toxicology and pharmacology, 2011, Volume: 31, Issue:1 Topics: Animals; Arsenic; Arsenic Poisoning; Caspase 3; Catalase; Chemical and Drug Induced Liver Injury; Dietary Supplements; DNA Fragmentation; Hydroxyl Radical; Intestinal Mucosa; Lipid Peroxidation; Liver; Male; Mitochondria, Liver; Mitochondrial Membranes; Nitric Oxide; Nitric Oxide Synthase Type II; Phosphates; Phosphorus, Dietary; Poisons; Rats; Rats, Wistar; Superoxide Dismutase	2011
Protective role of sinapic acid against arsenic: induced toxicity in rats. Chemico-biological interactions, 2011, Oct-15, Volume: 194, Issue:1 Topics: Animals; Antioxidants; Arsenic; Body Weight; Chemical and Drug Induced Liver Injury; Coumaric Acids; Humans; Lipid Peroxidation; Liver; Liver Diseases; Male; Oxidative Stress; Rats; Rats, Wistar	2011
Acetaminophen increases the risk of arsenic-mediated development of hepatic damage in rats by enhancing redox-signaling mechanism. Environmental toxicology, 2014, Volume: 29, Issue:2 Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arsenic; Catalase; Chemical and Drug Induced Liver Injury; Drug Synergism; Gene Expression Regulation; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Hepatocytes; Lipid Peroxidation; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidation-Reduction; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase; Water Pollutants, Chemical	2014
Silibinin potentially protects arsenic-induced oxidative hepatic dysfunction in rats. Toxicology mechanisms and methods, 2012, Volume: 22, Issue:4 Topics: Animals; Antioxidants; Arsenic; Chemical and Drug Induced Liver Injury; Male; Molecular Structure; Oxidative Stress; Rats; Rats, Wistar; Silybin; Silymarin	2012
RELATION BETWEEN CIRRHOSIS AND TRACE METAL CONTENT OF LIVER WITH SPECIAL REFERENCE TO PRIMARY BILIARY CIRRHOSIS AND COPPER. British medical journal, 1963, Dec-14, Volume: 2, Issue:5371 Topics: Arsenic; Chemical and Drug Induced Liver Injury; Cobalt; Copper; Gold; Hepatitis; Iron; Liver Cirrhosis; Liver Cirrhosis, Biliary; Metabolism; Toxicology; Trace Elements; Zinc	1963
ARSENIC AND SKIN CANCER. Transactions of the St. John's Hospital Dermatological Society, 1963, Volume: 49 Topics: Arsenic; Carcinogens; Carcinoma, Basal Cell; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Chemical and Drug Induced Liver Injury; Dermatitis Herpetiformis; Hepatitis; Humans; Keratosis; Keratosis, Actinic; Liver Cirrhosis; Pathology; Psoriasis; Skin Neoplasms; Toxicology	1963
Toxic hepatitis caused by prolonged inorganic arsenic intake; studies on liver dysfunction VII. New York state journal of medicine, 1951, Nov-01, Volume: 51, Issue:21 Topics: Arsenic; Arsenic Poisoning; Asthma; Chemical and Drug Induced Liver Injury; Humans; Liver; Liver Diseases	1951
Protective value of Aloe vera against some toxic effects of arsenic in rats. Phytotherapy research : PTR, 2005, Volume: 19, Issue:1 Topics: Administration, Oral; Alanine Transaminase; Alkaline Phosphatase; Aloe; Animals; Arsenic; Arsenic Poisoning; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Leukocyte Count; Liver; Male; Oxidative Stress; Phytotherapy; Plant Extracts; Protective Agents; Random Allocation; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances	2005
Therapeutic value of Hippophae rhamnoides L. against subchronic arsenic toxicity in mice. Journal of medicinal food, 2005,Fall, Volume: 8, Issue:3 Topics: Animals; Arsenic; Brain Chemistry; Chelating Agents; Chemical and Drug Induced Liver Injury; Drinking; Fruit; Glutathione; Hippophae; Kidney; Liver; Liver Diseases; Male; Mice; Oxidation-Reduction; Oxidative Stress; Plant Extracts; Porphobilinogen Synthase; Thiobarbituric Acid Reactive Substances	2005
Arsenic induces apoptosis in mouse liver is mitochondria dependent and is abrogated by N-acetylcysteine. Toxicology and applied pharmacology, 2007, Apr-15, Volume: 220, Issue:2 Topics: Acetylcysteine; Alanine Transaminase; Animals; Apoptosis; Arsenic; Chemical and Drug Induced Liver Injury; Free Radical Scavengers; Glutathione; Hepatocytes; In Situ Nick-End Labeling; Liver; Liver Function Tests; Male; Mice; Mice, Inbred BALB C; Mitochondria, Liver; Oxidative Stress; Poly(ADP-ribose) Polymerases; Triglycerides	2007
Protective effect of Mentha piperita against arsenic-induced toxicity in liver of Swiss albino mice. Basic & clinical pharmacology & toxicology, 2007, Volume: 100, Issue:4 Topics: Administration, Oral; Alanine Transaminase; Alkaline Phosphatase; Animals; Arsenic; Aspartate Aminotransferases; Body Weight; Chemical and Drug Induced Liver Injury; Glutathione; Injections, Intraperitoneal; Lipid Peroxidation; Liver; Male; Mentha piperita; Mice; Organ Size; Plant Extracts; Plant Leaves	2007
Protective effects of hepatocellular canalicular conjugate export pump (Mrp2) on sodium arsenite-induced hepatic dysfunction in rats. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2007, Volume: 58, Issue:6 Topics: Alanine Transaminase; Animals; Arsenic; Arsenic Poisoning; Arsenites; Aspartate Aminotransferases; ATP-Binding Cassette Transporters; Bile; Bile Canaliculi; Bilirubin; Blotting, Western; Chemical and Drug Induced Liver Injury; Enzyme Inhibitors; Female; Glutathione Peroxidase; Liver; Male; Malondialdehyde; Rats; Rats, Wistar; Sodium Compounds; Spectrophotometry, Atomic	2007
Arsenic and liver. The Journal of the Association of Physicians of India, 1983, Volume: 31, Issue:2 Topics: Animals; Arsenic; Chemical and Drug Induced Liver Injury; Humans; Hypertension, Portal; Liver; Liver Cirrhosis	1983
Study on chronic toxicity of arsenic trioxide in rats with special reference to the liver damages. Fukuoka igaku zasshi = Hukuoka acta medica, 1980, Volume: 71, Issue:1 Topics: Animals; Arsenic; Bile Ducts; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Liver Diseases; Male; Rats	1980
Sequence of exposure to cadmium and arsenic determines the extent of toxic effects in male Fischer rats. Toxicology, 1997, Jan-15, Volume: 116, Issue:1-3 Topics: Animals; Arsenic; Cadmium; Chemical and Drug Induced Liver Injury; Drug Administration Schedule; Drug Interactions; Kidney Diseases; Male; Metallothionein; Necrosis; Rats; Rats, Inbred F344; Testis	1997
Metallothionein-I/II null mice are more sensitive than wild-type mice to the hepatotoxic and nephrotoxic effects of chronic oral or injected inorganic arsenicals. Toxicological sciences : an official journal of the Society of Toxicology, 2000, Volume: 55, Issue:2 Topics: Administration, Oral; Animals; Arsenic; Blood Urea Nitrogen; Caspase 3; Caspases; Chemical and Drug Induced Liver Injury; Female; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Injections, Subcutaneous; Interleukin-1; Interleukin-6; Kidney; Kidney Diseases; Liver; Male; Metallothionein; Mice; Mice, Knockout; Organ Size; Tumor Necrosis Factor-alpha	2000
Arsenic and liver disease. Journal of the Indian Medical Association, 2001, Volume: 99, Issue:6 Topics: Adult; Animals; Arsenic; Arsenic Poisoning; Chemical and Drug Induced Liver Injury; Chronic Disease; Female; Glutathione; Humans; Liver; Liver Diseases; Male; Mice; Mice, Inbred BALB C; Organ Size; Sodium-Potassium-Exchanging ATPase; Water Pollution, Chemical	2001
Medical problems associated with arsenic exposure. Journal of occupational medicine. : official publication of the Industrial Medical Association, 1977, Volume: 19, Issue:6 Topics: Arsenic; Arsenic Poisoning; Chemical and Drug Induced Liver Injury; Dermatitis, Occupational; Heart Diseases; Hematologic Diseases; Humans; Kidney Diseases; Metallurgy; Neoplasms; Neurologic Manifestations; Occupational Diseases; Respiratory Tract Diseases; Washington	1977
Ultrastructural cytochemical analysis of intranuclear arsenic inclusions. Journal of toxicology and environmental health, 1987, Volume: 22, Issue:3 Topics: Amylases; Animals; Arsenic; Cell Nucleus; Chelating Agents; Chemical and Drug Induced Liver Injury; Fishes; Histocytochemistry; Liver	1987
[Letter: Non-cirrhotic portal fibrosis (hepatoportal sclerosis) following chronic arsenic poisoning]. Deutsche medizinische Wochenschrift (1946), 1974, Jul-05, Volume: 99, Issue:27 Topics: Adult; Arsenic; Arsenic Poisoning; Chemical and Drug Induced Liver Injury; Chronic Disease; Humans; Male; Psoriasis	1974
[Therapy related changes in leukemias]. Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1967, Jan-15, Volume: 22, Issue:2 Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Antineoplastic Agents; Arsenic; Chemical and Drug Induced Liver Injury; Cushing Syndrome; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Leukemia; Male; Middle Aged; Osteosclerosis; Peptic Ulcer; Prednisone; Radiotherapy; Sepsis; Thromboembolism; Transfusion Reaction	1967