Page last updated: 2024-08-24

aromasil and Breast Neoplasms

aromasil has been researched along with Breast Neoplasms in 706 studies

Research

Studies (706)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's15 (2.12)18.2507
2000's252 (35.69)29.6817
2010's368 (52.12)24.3611
2020's71 (10.06)2.80

Authors

AuthorsStudies
Amaral, C; Carvalho, RA; Correia-da-Silva, G; Costa, SC; Lopes, A; Roleira, FM; Tavares da Silva, E; Teixeira, N; Varela, CL1
Barmade, MA; Murumkar, PR; Tamboli, RS; Yadav, MR1
Alcaro, S; Amaral, C; Carvalho, RA; Correia-da-Silva, G; Costa, G; Costa, SC; Roleira, FM; Tavares-da-Silva, EJ; Teixeira, NA; Varela, CL1
Barrow, D; Eissa, AG; Foster, PA; Gee, J; Powell, LE; Simons, C1
Chen, JZ; Khan, MZI; Nazli, A; Uzair, M1
Abdel-Razeq, H; Abdel-Razeq, N; Abdulelah, H; Bater, R; Inserat, B; Salam, M; Sharaf, B1
Chen, G; Lazarus, P; Teslenko, I; Watson, CJW; Xia, Z1
Abraham, J; Budd, GT; Kruse, ML; LeGrand, SB; Mo, H; Montero, AJ; Moore, HCF; Renna, CE; Wang, L1
Iwata, H; Kimura, R; Lee, MJ; Masuda, N; Nishimura, Y; Saji, S; Sawaki, M; Shimomura, A; Tamura, K; Trepel, J; Yasojima, H; Yuno, A1
Acikgoz, O; Akin, S; Avci, N; Basaran, G; Beypinar, I; Bilgetekin, I; Bilici, A; Cinkir, HY; Değirmenci, M; Demir, A; Dogan, M; Erdem, D; Kaplan, MA; Menekse, S; Olmez, OF; Paydas, S; Sakalar, T; Sakin, A; Sezgin Goksu, S; Tanriverdi, O; Temiz, S; Tural, D; Turan, M; Turhal, S; Turker, S; Uslu, R; Uysal, M; Yildiz, F1
Abramson, VG; Del Valle, L; Ismail-Khan, R; Lush, RM; Majumder, S; Mayer, IA; Means-Powell, JA; Miele, L; Sanders, MS; Sorrentino, C; Tonetti, D1
Jing, F; Wang, H; Wang, Y1
Goncalves, A; Mezni, E; Sabatier, R; Vicier, C1
Laranjeira, MS; Magalhães, AI; Monteiro, FJ; Ribeiro, TP; Santos, JAM; Silva, PC1
Abreu, M; Afonso, A; Ferreira, M; Moreira, I; Sousa, S1
Chen, G; Lazarus, P; Luo, S; Teslenko, I; Trudeau, J; Truica, CI; Watson, CJW1
Joo, YY; Kang, EJ; Lee, K; Moon, SJ; Noh, E; Park, IH; Seo, JH1
Aruga, T; Iwasa, T; Iwata, H; Kaneda, A; Kaneko, K; Kawabata, A; Kobayashi, K; Lee, MJ; Masuda, N; Nakamura, R; Nishimura, Y; Saji, S; Seike, T; Tamura, K; Tokunaga, E; Trepel, JB; Tsurutani, J; Yamamoto, Y; Yamashita, T; Yonemori, K; Yuno, A1
Boughey, JC; Ellis, MJ; Hunt, KK; Leitch, AM; Meric-Bernstam, F; Olson, J; Suman, VJ; Unzeitig, G; Wingate, HF1
Almeida, CF; Amaral, C; Correia-da-Silva, G; Roleira, FMF; Tavares-da-Silva, E; Teixeira, N; Valente, MJ; Varela, C; Vinggaard, AM1
Cai, L; Chen, Q; Cui, S; Feng, J; Li, H; Liao, N; Ouyang, Q; Song, Y; Sun, Q; Sun, T; Teng, Y; Tong, Z; Wang, J; Wang, X; Xu, B; Yin, Y1
Bedrosian, I; Bertelsen, BE; Bonanni, B; Brown, PH; Castile, T; Crew, KD; D'Amico, M; DeCensi, A; Dimond, E; Gandini, S; Guasone, F; Guerrieri-Gonzaga, A; Heckman-Stoddard, BM; Johansson, H; Kumar, NB; Lazzeroni, M; Lee, JJ; Mellgren, G; Serrano, D; Spinaci, S; Szabo, E; Thomas, P; Veronesi, P; Viale, G; Vornik, LA; Weber, D1
Chan, RJ; Fardell, JE; Vardy, JL; Walker, A1
Boogerd, W; Kieffer, JM; Lee Meeuw Kjoe, PR; Meershoek-Klein Kranenbarg, E; Schagen, SB; Schilder, CM; Small, BJ; van de Velde, CJH; van der Wall, E1
Baktash, N; Biyukov, T; Blau, S; Burris, HA; Cortes, J; Díaz-Redondo, T; García-Sáenz, JÁ; Hart, L; Jañez, NM; Joaquim, A; Lemieux, J; Massey, D; Morales, S; Neven, P; Rugo, HS; Schmid, P1
Ahmad, S; Alam, M; Amin, S; Mir, SR; Perwez, A; Rizvi, MMA; Rizwanullah, M1
Ferini, G; Strazzanti, A; Zagardo, V1
Jia, Y; Liu, Y; Lu, Y; Nong, L; Qin, F; Tan, A; Tang, J; Wang, H; Zhong, W1
Arpino, G; Bachelot, T; Cristofanilli, M; De Laurentiis, M; De Placido, P; De Placido, S; Del Mastro, L; Generali, D; Giordano, A; Giuliano, M; Jerusalem, G; Milani, M; Pistilli, B; Prat, A; Puglisi, F; Rognoni, C; Schettini, F; Thomas, G; Venturini, S1
Elkodairy, KA; Elzoghby, AO; Gaber, M; Hany, M; Helmy, MW; Mokhtar, S1
DiNardo, D; Farkas, A; Merriam, S; Vanderberg, R1
Coates, AS; Colleoni, M; Di Leo, A; Fleming, GF; Francis, PA; Gelber, RD; Goldhirsch, A; Gómez, HL; Láng, I; Pagani, O; Pinotti, G; Regan, MM; Tondini, C; Viale, G; Walley, BA1
Robert, M; Turner, N1
Ahn, HK; Ahn, JS; Im, SA; Im, YH; Jung, KH; Kang, SY; Kim, GM; Kim, HJ; Kim, JH; Kim, JY; Kim, SB; Kim, TY; Koh, SJ; Lee, JI; Lee, KE; Lee, KH; Lee, MH; Park, IH; Park, YH; Sohn, J1
Francis, PA2
Boven, E; Dercksen, WM; Jager, A; Jansen, MPHM; Konings, IRHM; Kruger, DT; Martens, JWM; Oulad Hadj, J; Sleijfer, S1
Chen, J; Fan, Y; He, T; Huang, Q; Li, P; Lv, Q; Wu, Y; Xiang, M; Yang, D; Yang, W; Zhang, X; Zhou, R1
Limmer, A; Robare, S; Swali, R1
Petit, T1
Bartsch, R; Egle, D; Gnant, M; Greil, R; Haslbauer, F; Helfgott, R; Hennebelle, M; Hock, K; Hubalek, M; Lang, A; Marth, C; Mraz, B; Öhler, L; Petru, E; Pfeiler, G; Redl, A; Steger, GG; Tinchon, C1
Guillaume, Z; Lillo-Lelouet, A; Marret, G; Medioni, J; Oudard, S; Simonaggio, A1
Bahrami, N; Chang, G; Chen, S; Geisler, J; Gravdehaug, B; Kanaya, N; Loeng, M; Park, D; Sauer, T1
Fakolade, A; Fan, T1
Ciruelos, E; Conte, P; Gavila, J; Generali, D; Jerusalem, G; Lang, I; Martin, M; Martínez-Serrano, MJ; Montemurro, F; Neven, P; Perelló, MF; Tjan-Heijnen, VCG1
Chen, PH; Ho, CL; Huang, TC; Kang, YN; Lee, CH; Lin, C; Wu, YY1
Chiabudini, M; Decker, T; Falkenstein, J; Hagen, V; Hahn, A; Indorf, M; Klare, P; Kurbacher, CM; Maintz, C; Potthoff, K; Runkel, E; Sent, D; Söling, U; Vehling-Kaiser, U1
Bianchi, GV; Capri, G; Corti, F; de Braud, F; Ligorio, F; Manglaviti, S; Nichetti, F; Rea, CG; Vernieri, C; Zattarin, E1
Huma, J; Jingxiang, H; May, LM; Xue Ting, O1
Amaral, C; Fernandes, PA; Ferreira Almeida, C; João Ramos, M; Oliveira, A; Teixeira, N1
Jamal, QMS1
Gui, L; Li, Q; Luo, Y; Sun, J; Wang, L; Wang, Q; Zhang, P; Zhang, S1
Coudert, B; Goirand, F; Guérard, P; Macaire, P; Schmitt, A; Vaury, C1
Ingle, JN; Qin, S; Wang, L; Yu, J; Zayas, J1
Beelen, KJ; Boven, E; de Valk, B; Kruger, DT; Linn, SC; Nieuwenhuis, M; Opdam, M; Sanders, J; van der Noort, V1
Chen, C; Guan, J; Huang, X; Lin, Y; Mao, F; Shen, S; Sun, Q; Wang, C; Yao, R; Zhang, X; Zhao, J; Zhou, Y; Zhu, H1
DiNome, ML; Ganz, PA; Graham, D1
Bartlett, JMS; Blok, EJ; Duijm-de Carpentier, M; Hasenburg, A; Hozumi, Y; Kroep, JR; Liefers, GJ; Markopoulos, CJ; Meershoek-Klein Kranenbarg, E; Noordhoek, I; Paridaens, R; Portielje, JEA; Putter, H; Rea, DW; Rutgers, EJT; Seynaeve, C; van de Velde, CJH; Vannetzel, JM1
Kohli, K; Mangla, B; Neupane, YR; Shafi, S; Singh, A1
Chen, G; Goss, P; Ho, V; Lazarus, P; Luo, S; Pasquet, R; Richardson, H; Tu, D1
Barba, M; Barchiesi, G; Krasniqi, E; Mazzotta, M; Pizzuti, L; Vici, P; Villa, A1
Cao, Y; Ding, J; Fu, W; Guo, Y; Jiang, X; Li, K1
Banda, K; Fritzsche, D; Indorf, A; Miske, A1
Abramson, V; Awada, A; Biganzoli, L; Chan, S; Colleoni, M; Garcia-Estevez, L; Gucalp, A; Hart, L; Holmes, F; Kelly, CM; Krop, I; Markova, D; Morris, PG; O'Brien, T; Schwartzberg, L; Sica, L; Steinberg, J; Tarazi, J; Traina, T; Trudeau, M; Winer, E; Yardley, DA; Zamagni, C; Zhu, Z1
Al Rabadi, L; Cook, MM; Kaempf, AJ; Mitri, ZI; Saraceni, MM; Savin, MA1
Hayashi, Y; Inoue, K; Kai, T; Kurosumi, M; Ninomiya, J; Saito, T; Takei, H1
Ahn, HK; Im, SA; Jung, KH; Kang, SY; Kim, GM; Kim, JH; Lee, J; Park, IH; Park, YH1
Adachi, M; Amemiya, T; Hata, H; Hayashi, N; Kashiwabara, K; Kikawa, Y; Kondo, N; Mitsunaga, S; Mukai, H; Naito, M; Nakagami, K; Nakatsukasa, K; Niikura, N; Ota, Y; Shibuya, Y; Taniike, N; Umeda, M; Watanabe, KI; Yamanaka, T; Yamashita, T1
Adamson, D; Bergh, J; Bogenrieder, T; Cortés, J; Crown, J; Espadero, RM; Gonçalves, A; Huang, DC; Im, SA; Jerusalem, G; Lee, KS; Lu, YS; Martínez, N; Morales, S; Neven, P; Pérez-Fidalgo, JA; Prat, A; Sablin, MP; Schlieker, L; Schmid, P1
Chohan, B; Ferguson, A; Lewis, M; Nambi, R; Narang, I; Panthagani, AP1
Apostolaki, S; Georgoulia, N; Georgoulias, V; Hatzidaki, D; Kallergi, G; Koinis, F; Kotsakis, A; Nikolaou, C; Politaki, E; Spiliotaki, M; Tsoukalas, N; Xenidis, N1
Baak-Pablo, R; Böhringer, S; de Groot, S; Gelderblom, H; Guchelaar, H-; Houtsma, D; Kranenbarg, EM; Kroep, JR; Seynaeve, CM; van de Velde, CJH1
Jeon, SY; Lee, KS; Park, IH; Sim, SH; Yang, HN1
Abdel-Razeq, H; Adhav, A; Aksoy, S; Bowles, J; Chae, Y; Chang, YC; Cinkir, HY; Im, SA; Im, YH; Jeong, J; Karabulut, B; Kim, SB; Lee, KS; Park, BW; Slimane, K; Xue, H1
Barman, P; Cairns, J; Carlson, EE; Ellis, MJ; Gao, H; Goetz, MP; Goodnature, B; Goss, PE; Ingle, JN; Kalari, KR; Shepherd, LE; Wang, L; Weinshilboum, RM1
Habibi-Anbouhi, M; Mohammadi, E; Tabatabaei, M; Tafazzoli-Shadpour, M1
Accornero, CA; Bonanni, B; Brown, PH; Cagnacci, S; Crew, KD; D'Amico, M; Gandini, S; Guasone, F; Guerrieri-Gonzaga, A; Heckman-Stoddard, B; Kumar, NB; Lee, J; Serrano, D; Spinaci, S; Szabo, E; Thomas, P; Vicini, E; Vornik, LA; Webber, TB1
Brown-Glaberman, UA; Budd, GT; Burkard, ME; Connolly, RM; Faller, BA; Kaufman, PA; Lee, MJ; Levine, EG; Miller, KD; Onitilo, AA; Piekarz, RL; Royce, ME; Smith, KL; Sparano, JA; Thomas, A; Trepel, JB; Winn, JS; Wolff, AC; Zhao, F1
Almeida, CF; Amaral, C; Augusto, TV; Correia-da-Silva, G; Teixeira, N1
Alba, E; Alvarez, E; Antón, A; Bermejo, B; Calvo, L; Carrasco, E; Casas, M; Ciruelos, E; Corsaro, M; Csöszi, T; de la Haba-Rodriguez, J; Gal-Yam, E; Garcia-Palomo, A; Gil-Gil, M; González-Santiago, S; Kahan, Z; Lang, I; López, IÁ; Margeli, M; Martín, M; Morales, S; Muñoz, M; Murillo, L; Ramos, M; Rodrigálvarez, G; Rodríguez, CA; Ruiz-Borrego, M; Servitja, S; Zielinski, C1
Beck, JT; Chambers, MS; Dhillon, N; Glaspy, JA; Hwang, LC; Litton, JK; Mayer, IA; Meiller, TF; Nangia, C; Peguero, JA; Pluard, TJ; Rugo, HS; Sabo, JR; Seneviratne, L; Sweetman, RW1
Awada, A; Baselga, J; Blum, JL; Ciruelos, EM; Cortes, J; Eaton, L; Ebbinghaus, S; Ewertz, M; Gause, C; Haddad, T; Im, E; Jones, MB; Mauro, D; Morales, SM; Moy, B; Pathiraja, K; Ruddy, KJ; Rugo, HS; Tan, AR; Vuylsteke, P1
Cascinu, S; Depenni, R; Filieri, ME; Grizzi, G; Omarini, C; Piacentini, F1
Bilancia, D; Cairo, G; Cazzaniga, ME; Chiuri, VE; Ciccarese, M; Cusmai, A; De Matteis, E; Fabi, A; Febbraro, A; Forcignanò, R; Giampaglia, M; Giordano, G; Giotta, F; La Verde, N; Latorre, A; Lorusso, V; Lupo, LI; Maiello, E; Morritti, M; Moscetti, L; Palmiotti, G; Petrucelli, L; Romito, S; Scavelli, C; Surico, G1
Chanawong, A; Hu, DG; Mackenzie, PI; McKinnon, RA; Meech, R1
Caramia, F; Joshi, S; Loi, S; Moodie, K; Savas, P; Van Geelen, C; Wein, L1
Ascione, G; Barone, CA; Bighin, C; Bordonaro, R; Cazzaniga, ME; Cognetti, F; Foglietta, J; Frassoldati, A; Generali, D; Goffredo, F; Ionta, MT; Latini, L; Mafodda, A; Mariani, G; Michelotti, A; Minisini, AM; Molino, A; Montemurro, F; Nolè, F; Nuzzo, F; Piacentini, F; Piovano, P; Portera, G; Riccardi, F; Roila, F; Romito, S; Sartori, D; Schirone, A; Simoncini, EL; Testore, F; Vici, P1
Flockhart, DA; Hayes, DF; Henry, NL; Kadakia, KC; Kidwell, KM; Otte, JL; Seewald, NJ; Snyder, CF; Stearns, V; Storniolo, AM1
Chirila, C; Colosia, A; Iyer, S; Kaye, JA; Ling, C; Mitra, D; Odom, D1
Ali, SM; Budd, GT; Chapman, JW; Elliott, CR; Ellis, MJ; Garg, A; Goss, PE; Han, L; Ingle, JN; Leitzel, K; Lipton, A; Pritchard, KI; Rabaglio, M; Shepherd, LE; Sledge, GW1
Alvarez, I; Andersen, J; Bertelli, G; Bliss, JM; Coates, AS; Coleman, R; Coombes, RC; Del Mastro, L; Dodwell, D; Fallowfield, L; Holmberg, S; Jassem, J; Jones, S; Kilburn, L; Lønning, PE; Morden, JP; Nicholas, H; Ortmann, O; Paridaens, R; Snowdon, C; van de Velde, C1
Gourd, E1
Baird, CC; Chen, G; Lazarus, P; Leitzel, K; Luo, S; Truica, C1
Clark, BL; Kamdem, LK; Murphy, MA1
Bellet, M; Bernhard, J; Burstein, HJ; Coates, AS; Colleoni, M; Dane, F; Fleming, GF; Francis, PA; Gelber, RD; Goldhirsch, A; Gómez, HL; Luo, W; Moreira, A; Nottage, M; Pagani, O; Parmar, V; Perelló, A; Price, KN; Regan, MM; Ribi, K; Saha, P; Stewart, J; Torres, R; Vorobiof, D; Walley, BA1
Gemignani, ML; Hetzel, DJ1
Afonso, N; Baselga, J; Blum, JL; Campone, M; Cortes, J; Denker, A; Eaton, L; Ferreira, M; Gause, CK; Im, E; Jones, MB; Mauro, DJ; Morales, SM; Musolino, A; Park, KH; Ro, J; Rugo, HS; Tan, AR; Trédan, O; Wang, Z1
Airoldi, M; Arcangeli, V; Artale, S; Atzori, F; Ballerio, A; Bianchi, GV; Blasi, L; Campidoglio, S; Cazzaniga, ME; Ciccarese, M; Clivio, L; Cursano, MC; Fabi, A; Ferrari, L; Ferzi, A; Ficorella, C; Frassoldati, A; Fumagalli, A; Garrone, O; Gebbia, V; Generali, D; La Verde, N; Maur, M; Michelotti, A; Moretti, G; Musolino, A; Palumbo, R; Piezzo, M; Pistelli, M; Porpiglia, M; Sartori, D; Scavelli, C; Schirone, A; Torri, V; Turletti, A; Valerio, MR; Vici, P; Zambelli, A1
Martin, M1
Blok, EJ; Derks, MGM; Dirix, LY; Hasenburg, A; Kranenbarg, EM; Kroep, JR; Liefers, GJ; Markopoulos, C; Nortier, JWR; Paridaens, R; Putter, H; Rea, D; Seynaeve, C; Smeets, JBE; van de Velde, CJH1
Chlebowski, RT; Lin, EM; Pan, K1
He, Y; Huang, Y; Wang, C; Wu, K; Zhang, J; Zheng, S1
Barba, M; Botti, C; Botticelli, A; Buglioni, S; Catenaro, T; D'Onofrio, L; Di Filippo, S; di Lauro, L; Ferranti, F; Gamucci, T; Giordano, A; Iezzi, L; Marchetti, P; Maugeri-Saccà, M; Mentuccia, L; Moscetti, L; Natoli, C; Pizzuti, L; Sanguineti, G; Santini, D; Scinto, AF; Sergi, D; Sperati, F; Tomao, S; Vici, P1
Briceño, CA; Jackson, K; Sulewski, ME1
Abu-Serie, MM; El-Lakany, SA; Elgindy, NA; Elzoghby, AO; Helmy, MW2
Chamseddine, AN; Mir, O; Paci, A; Ropert, S1
Beliera, A; Carabantes, F; Ciruelos, E; Fernández, Y; Fonseca, R; García-Sáenz, JA; Gavilá, J; Martínez de Dueñas, E; Martínez-Jáñez, N; Murillo, L; Vidal, M1
Adams, S; Bonakdar, M; Budan, B; Goldberg, JD; Gu, P; Iwano, A; Jhaveri, K; Kozhaya, L; Kwa, M; Li, X; Meyers, M; Muggia, F; Novik, Y; Oratz, R; Raad, R; Speyer, J; Tavukcuoglu, E; Unutmaz, D; Wu, J1
Agarwal, SK; Bartlett, J; Bongartz, T; Chapman, JW; Chen, B; Gelmon, K; Goss, PE; Hilsenbeck, SG; Ingle, JN; Kalari, KR; Niravath, P; Osborne, CK; Pritchard, K; Rimawi, MF; Shepherd, LE; Welschhans, RL1
Bartlett, JMS; Bliss, JM; Cheang, MCU; Coombes, RC; Jassem, J; Lønning, PE; Morden, J; Palmieri, C; Porta, N; Rasmussen, BB; Shaaban, A; Speirs, V; van De Velde, CJ; Verhoeven, D; Viale, G1
Chen, BE; Goss, PE; Liedke, PER; O'Shaughnessy, J; Parulekar, WR; Ramjeesingh, R; Shepherd, LE; Strasser-Weippl, K; Sudan, G1
Deng, Y; Tian, W; Wu, M1
Kubo, H; Maeda, N; Nagano, H; Nagashima, Y; Sakamoto, K; Sato, Y; Suzuki, N; Takeda, S; Yamamoto, S1
Itoh, Y; Makabe, H; Osaki, S; Saeki, T; Sugitani, I; Takahashi, M; Takahashi, T; Todo, M; Ueda, S1
Bufill, JA; Cella, D; Chapman, JW; Goss, PE; LaFrancis, IE; Mattar, BI; Nagargoje, GG; Nikcevich, DA; Schultz, WC; Shepherd, LE; Sledge, GW; Vemuri, R; Wagner, LI; Whelan, TJ; Zhao, F1
Dirix, LY1
Amoroso, D; Arpino, G; Bernardo, A; Bisagni, G; Carlini, P; Cognetti, F; Cogoni, AA; De Laurentiis, M; De Placido, S; Del Mastro, L; Foglietta, J; Frassoldati, A; Gallo, C; Gori, S; Gravina, A; Lai, A; Laudadio, L; Lauria, R; Lorusso, V; Mocerino, C; Montemurro, F; Moretti, G; Moscetti, L; Nuzzo, F; Perrone, F; Riccardi, F; Rizzo, S; Russo, A; Sarobba, MG; Verusio, C1
Alunni-Fabbroni, M; Andergassen, U; Beckmann, MW; Fasching, PA; Fehm, T; Friedl, TWP; Gade, J; Janni, W; Lichtenegger, W; Lorenz, R; Mahner, S; Müller, V; Pantel, K; Polasik, A; Rack, B; Rezai, M; Schindlbeck, C; Schneeweiss, A; Schochter, F; Soeling, U; Tesch, H; Trapp, E; Tzschaschel, M1
Arakawa, A; Horimoto, Y; Ichikawa, Y; Kobayashi, T; Okazaki, M; Saito, M; Tanabe, M; Tokuda, E1
Evans, DG; Howell, A; Howell, SJ1
Chaiyakunapruk, N; Imanaka, Y; Kunisawa, S; Lertjanyakun, V1
Blau, S; Burris, H; de Boer, RH; Ejlertsen, B; Ewertz, M; Fan, J; Hurvitz, S; Jerusalem, G; Kovalenko, E; Landherr, L; Louveau, AL; Noel-Baron, F; Özgüroglu, M; Taran, T; Yardley, DA1
Bellet, M; Bonnefoi, HR; Buchholz, S; Burstein, HJ; Ciruelos, E; Climent, MA; Coates, AS; Coleman, R; Colleoni, M; Davidson, NE; Debled, M; Di Leo, A; Fleming, GF; Francis, PA; Gelber, RD; Geyer, CE; Goetz, MP; Goldhirsch, A; Gómez, HL; Ingle, JN; Láng, I; Maibach, R; Martino, S; Pagani, O; Pavesi, L; Pinotti, G; Puglisi, F; Rabaglio-Poretti, M; Regan, MM; Ruepp, B; Ruhstaller, T; Spazzapan, S; Stearns, V; Tondini, C; Walley, BA; Winer, EP1
Bastiaannet, E; de Glas, NA; Derks, MGM; Dirix, LY; Hasenburg, A; Liefers, GJ; Markopoulos, C; Nortier, JWR; Portielje, JEA; Putter, H; Rea, D; Seynaeve, C; van de Velde, CJH; van de Water, W1
Bartlett, JMS; Bayani, J; Bennett, L; Cheng, K; Dickson, A; Dirix, LY; Edwards, J; Hasenburg, A; Horgan, PG; Kieback, DG; Mallon, EA; Markopoulos, C; McMillan, DC; Quintayo, MA; Rea, DW; Roseweir, AK; Seynaeve, C; van de Velde, CJH1
Hattori, A; Hirano, A; Inoue, H; Kamimura, M; Kodera, A; Matsuoka, A; Naritaka, Y; Ogura, K; Sakaguchi, S; Shimizu, T; Tanaka, N; Yukawa, H1
Decker, T; Distelrath, A; Fasching, PA; Hadji, P; Janni, W; Kreuzeder, J; Kurbacher, CM; Lüftner, D; Lux, MP; Marmé, F; Mundhenke, C; Muth, M; Quiering, C; Schneeweiss, A; Stoetzer, O; Taran, FA; Tesch, H1
O'Shaughnessy, J; Royce, M; Thaddeus Beck, J1
Barbolini, M; Bettelli, S; Caprera, C; Cascinu, S; Conte, PF; Filieri, ME; Guaitoli, G; Kaleci, S; Maiorana, A; Manfredini, S; Moscetti, L; Nasso, C; Omarini, C; Piacentini, F1
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Sonoo, H1
Attolico, M; Crucitta, E; De Lena, M; Lorusso, V; Mazzei, A; Sambiasi, D1
Bajetta, E; Cervek, J; Di Salle, E; Dirix, LY; Fein, LE; Fowst, C; Jones, SE; Kaufmann, M; Massimini, G; Piscitelli, G; Polli, A1
Buzdar, A1
Cattel, F; Messori, A; Trippoli, S; Vaiani, M1
Hillner, BE; Radice, D1
Kerbrat, P; Lefeuvre, C1
Nabholtz, JM1
Mamounas, EP1
Hamilton, A; Volm, M1
Buzdar, A; Howell, A1
Murray, R1
Nabholtz, JM; Reese, DM1
Bando, H; Saji, S; Toi, M1
Dickler, MN; Norton, L1
Dixon, JM; Miller, WR1
Junker, A; Possinger, K; Wiedemann, GJ1
Jönsson, B; Lindgren, P; Radice, D; Redaelli, A1
Jones, SA; Jones, SE1
Buzdar, A; Johnson, PE1
Goss, PE1
Beex, L; Biganzoli, L; Cufer, T; Dirix, L; Duchateau, L; Lobelle, JP; Lohrisch, C; Nooij, M; Paridaens, R; Piccart, M; Van Hoorebeeck, I1
Soudon, J1
Crucitta, E; De Lena, M; Fornier, MN; Locopo, N; Lorusso, V; Silvestris, N1
Benedetto, C; De Nicola, B; Ferraris, F; Genta, F; Piccinno, R; Porpiglia, M; Vicelli, R1
Lombardi, P1

Reviews

175 review(s) available for aromasil and Breast Neoplasms

ArticleYear
Developing steroidal aromatase inhibitors-an effective armament to win the battle against breast cancer.
    European journal of medicinal chemistry, 2015, Nov-13, Volume: 105

    Topics: Aromatase; Aromatase Inhibitors; Breast Neoplasms; Drug Design; Female; Humans; Models, Molecular; Molecular Structure

2015
An overview on Estrogen receptors signaling and its ligands in breast cancer.
    European journal of medicinal chemistry, 2022, Nov-05, Volume: 241

    Topics: Breast Neoplasms; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Female; Humans; Ligands; Male; Receptors, Estrogen

2022
Role of Exemestane in the Treatment of Estrogen-Receptor-Positive Breast Cancer: A Narrative Review of Recent Evidence.
    Advances in therapy, 2022, Volume: 39, Issue:2

    Topics: Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Estrogens; Female; Humans; Postmenopause

2022
[Updates in hormone-receptor-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced breast cancer in 2021].
    Bulletin du cancer, 2022, Volume: 109, Issue:2

    Topics: Aged; Androstadienes; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Breast Neoplasms; Class I Phosphatidylinositol 3-Kinases; Clinical Trials as Topic; Female; Humans; Imidazoles; Immune Checkpoint Inhibitors; Letrozole; Leuprolide; Oxazepines; Phosphoinositide-3 Kinase Inhibitors; Piperazines; Progression-Free Survival; Pyridines; Receptor, ErbB-2; Receptors, Estrogen; Selective Estrogen Receptor Modulators

2022
Endocrine treatment versus chemotherapy in postmenopausal women with hormone receptor-positive, HER2-negative, metastatic breast cancer: a systematic review and network meta-analysis.
    The Lancet. Oncology, 2019, Volume: 20, Issue:10

    Topics: Aminopyridines; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Bevacizumab; Breast Neoplasms; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Everolimus; Female; Fulvestrant; Humans; Letrozole; Network Meta-Analysis; Paclitaxel; Piperazines; Postmenopause; Progression-Free Survival; Purines; Pyridines; Randomized Controlled Trials as Topic; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone

2019
Comparative effectiveness of tamoxifen, toremifene, letrozole, anastrozole, and exemestane on lipid profiles in breast cancer patients: A network meta-analysis.
    Medicine, 2020, Volume: 99, Issue:2

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Humans; Letrozole; Lipids; Network Meta-Analysis; Research Design; Tamoxifen; Toremifene

2020
[Endocrine adjuvant treatment specific features for young breast cancer women].
    Bulletin du cancer, 2019, Volume: 106, Issue:12S1

    Topics: Adult; Amenorrhea; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Goserelin; Humans; Luteolytic Agents; Neoplasm Recurrence, Local; Randomized Controlled Trials as Topic; Selective Estrogen Receptor Modulators; Tamoxifen; Time Factors; Triptorelin Pamoate

2019
Endocrine therapies in postmenopausal women with hormone receptor-positive, human epidermal growth factor receptor 2-negative, pretreated, advanced breast cancer: A network meta-analysis.
    Medicine, 2020, Volume: 99, Issue:13

    Topics: Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Breast Neoplasms; Disease-Free Survival; Everolimus; Female; Fulvestrant; Humans; Neoplasm Grading; Network Meta-Analysis; Piperazines; Postmenopause; Pyridines; Randomized Controlled Trials as Topic; Receptor, ErbB-2

2020
Everolimus versus alpelisib in advanced hormone receptor-positive HER2-negative breast cancer: targeting different nodes of the PI3K/AKT/mTORC1 pathway with different clinical implications.
    Breast cancer research : BCR, 2020, 04-06, Volume: 22, Issue:1

    Topics: Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Everolimus; Female; Humans; Mechanistic Target of Rapamycin Complex 1; Multicenter Studies as Topic; Neoplasm Metastasis; Patient Safety; Phosphatidylinositol 3-Kinases; Prospective Studies; Proto-Oncogene Proteins c-akt; Randomized Controlled Trials as Topic; Receptor, ErbB-2; Retrospective Studies; Treatment Outcome

2020
Estrogen receptor-positive (ER
    Biochemical pharmacology, 2020, Volume: 177

    Topics: Androstadienes; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Estrogen Receptor alpha; Estrogen Receptor beta; Fadrozole; Female; Fulvestrant; Gene Expression; Humans; Molecular Targeted Therapy; Tamoxifen

2020
Comparison of palbociclib in combination with letrozole or fulvestrant with endocrine therapies for advanced/metastatic breast cancer: network meta-analysis.
    Current medical research and opinion, 2017, Volume: 33, Issue:8

    Topics: Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Bayes Theorem; Breast Neoplasms; Disease-Free Survival; Estradiol; Everolimus; Female; Fulvestrant; Humans; Letrozole; Network Meta-Analysis; Nitriles; Piperazines; Pyridines; Randomized Controlled Trials as Topic; Triazoles

2017
Current advances in endocrine therapy options for premenopausal women with hormone receptor positive breast cancer.
    Gynecologic oncology, 2017, Volume: 147, Issue:1

    Topics: Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Premenopause; Randomized Controlled Trials as Topic; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen

2017
Efficacy and safety of endocrine monotherapy as first-line treatment for hormone-sensitive advanced breast cancer: A network meta-analysis.
    Medicine, 2017, Volume: 96, Issue:33

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Disease-Free Survival; Estradiol; Female; Fulvestrant; Humans; Letrozole; Neoplasms, Hormone-Dependent; Network Meta-Analysis; Nitriles; Receptor, ErbB-2; Tamoxifen; Triazoles

2017
Personalized prevention in high risk individuals: Managing hormones and beyond.
    Breast (Edinburgh, Scotland), 2018, Volume: 39

    Topics: Adult; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chemoprevention; Early Detection of Cancer; Female; Genes, BRCA1; Genes, BRCA2; Humans; Mammography; Middle Aged; Nitriles; Precision Medicine; Raloxifene Hydrochloride; Risk Assessment; Risk Factors; Tamoxifen; Triazoles

2018
Everolimus-based combination therapies for HR+, HER2- metastatic breast cancer.
    Cancer treatment reviews, 2018, Volume: 69

    Topics: Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Everolimus; Female; Humans; Prognosis; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Sirolimus; Tamoxifen

2018
CDK4/6 inhibition versus mTOR blockade as second-line strategy in postmenopausal patients with hormone receptor-positive advanced breast cancer: A network meta-analysis.
    Medicine, 2019, Volume: 98, Issue:1

    Topics: Aminopyridines; Androstadienes; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Breast Neoplasms; ErbB Receptors; Everolimus; Female; Fulvestrant; Humans; Network Meta-Analysis; Piperazines; Postmenopause; Progression-Free Survival; Protein Kinase Inhibitors; Pyridines; TOR Serine-Threonine Kinases

2019
Efficacy and safety of adjuvant endocrine therapy in premenopausal patients with early-stage hormone receptor-positive breast cancer: A meta-analysis of randomized controlled trials.
    The breast journal, 2019, Volume: 25, Issue:6

    Topics: Androstadienes; Antineoplastic Agents, Hormonal; Breast Neoplasms; Female; Glucose Intolerance; Humans; Neoplasm Staging; Pharmacovigilance; Premenopause; Receptors, Estrogen; Tamoxifen; Treatment Outcome

2019
Everolimus in combination with exemestane: a review of its use in the treatment of patients with postmenopausal hormone receptor-positive, HER2-negative advanced breast cancer.
    Drugs, 2013, Volume: 73, Issue:5

    Topics: Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Everolimus; Female; Humans; Postmenopause; Randomized Controlled Trials as Topic; Receptor, ErbB-2; Secondary Prevention; Sirolimus; Treatment Outcome

2013
Exemestane: one part of the chemopreventive spectrum for ER-positive breast cancer.
    Breast (Edinburgh, Scotland), 2013, Volume: 22, Issue:3

    Topics: Androstadienes; Anticarcinogenic Agents; Aromatase Inhibitors; Breast Neoplasms; Humans; Receptors, Estrogen

2013
Pharmacogenomics of endocrine therapy in breast cancer.
    Journal of human genetics, 2013, Volume: 58, Issue:6

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Genome-Wide Association Study; Humans; Japan; Letrozole; Musculoskeletal Physiological Phenomena; Nitriles; Pharmacogenetics; Phenotype; Postmenopause; Raloxifene Hydrochloride; Randomized Controlled Trials as Topic; Selective Estrogen Receptor Modulators; Tamoxifen; Triazoles

2013
Impact of metabolizing enzymes on drug response of endocrine therapy in breast cancer.
    Expert review of molecular diagnostics, 2013, Volume: 13, Issue:4

    Topics: Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Biomarkers, Pharmacological; Breast Neoplasms; Cytochrome P-450 CYP2D6; Female; Humans; Letrozole; Nitriles; Receptors, Estrogen; Tamoxifen; Triazoles

2013
Management of adverse events in patients with hormone receptor-positive breast cancer treated with everolimus: observations from a phase III clinical trial.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2013, Volume: 21, Issue:8

    Topics: Adult; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Clinical Trials, Phase III as Topic; Everolimus; Exanthema; Female; Humans; Hyperglycemia; Pneumonia; Sirolimus; Stomatitis; Treatment Outcome

2013
Role of inhibitors of mammalian target of rapamycin in the treatment of luminal breast cancer.
    Anti-cancer drugs, 2013, Volume: 24, Issue:8

    Topics: Androstadienes; Animals; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Biomarkers, Tumor; Breast Neoplasms; Disease-Free Survival; Everolimus; Female; Humans; Molecular Targeted Therapy; Protein Kinase Inhibitors; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases; Treatment Outcome

2013
New strategies to overcome resistance to mammalian target of rapamycin inhibitors in breast cancer.
    Current opinion in oncology, 2013, Volume: 25, Issue:6

    Topics: Androstadienes; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Clinical Trials as Topic; Drug Therapy, Combination; Everolimus; Female; Humans; Mitogen-Activated Protein Kinases; Molecular Targeted Therapy; Protein Kinase Inhibitors; Receptor, IGF Type 1; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases; Trastuzumab; Treatment Outcome

2013
Co-targeting estrogen receptor and HER2 pathways in breast cancer.
    Breast (Edinburgh, Scotland), 2014, Volume: 23, Issue:1

    Topics: Anastrozole; Androstadienes; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Estradiol; Everolimus; Female; Fulvestrant; Gefitinib; Humans; Lapatinib; Letrozole; Molecular Targeted Therapy; Nitriles; Quinazolines; Receptor, ErbB-2; Receptors, Estrogen; Signal Transduction; Sirolimus; Tamoxifen; Trastuzumab; Triazoles

2014
Comparative efficacy of everolimus plus exemestane versus fulvestrant for hormone-receptor-positive advanced breast cancer following progression/recurrence after endocrine therapy: a network meta-analysis.
    Breast cancer research and treatment, 2014, Volume: 143, Issue:1

    Topics: Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Disease Progression; Estradiol; Everolimus; Female; Fulvestrant; Humans; Neoplasm Recurrence, Local; Neoplasm Staging; Proportional Hazards Models; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Sirolimus; Treatment Outcome

2014
The renaissance of endocrine therapy in breast cancer.
    Current opinion in obstetrics & gynecology, 2014, Volume: 26, Issue:1

    Topics: Adult; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Drug Administration Schedule; Estradiol; Female; Fulvestrant; Humans; Middle Aged; Ovariectomy; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Tamoxifen; Treatment Outcome

2014
Aromatase inhibitors in the breast cancer clinic: focus on exemestane.
    Endocrine-related cancer, 2014, Volume: 21, Issue:1

    Topics: Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans

2014
Current concepts in breast cancer chemoprevention.
    Polskie Archiwum Medycyny Wewnetrznej, 2014, Volume: 124, Issue:4

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemoprevention; Estrogen Antagonists; Estrogens; Female; Humans; Incidence; Nitriles; Postmenopause; Premenopause; Prospective Studies; Raloxifene Hydrochloride; Randomized Controlled Trials as Topic; Selective Estrogen Receptor Modulators; Tamoxifen; Treatment Outcome; Triazoles

2014
[Exemestane-everolimus in HER2-negative, hormonal receptor-positive, post-menopausal metastatic breast cancer with resistance to non-steroidal aromatase inhibitor: a new option].
    Bulletin du cancer, 2014, Volume: 101, Issue:3

    Topics: Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Drug Resistance, Neoplasm; Everolimus; Female; Humans; Neoplasm Proteins; Phosphatidylinositol 3-Kinases; Randomized Controlled Trials as Topic; Sirolimus; TOR Serine-Threonine Kinases

2014
[Combination of exemestane and everolimus may produce toxic side effects: a new treatment option for metastatic hormone-sensitive breast cancer].
    Nederlands tijdschrift voor geneeskunde, 2014, Volume: 158

    Topics: Aged; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Drug Therapy, Combination; Everolimus; Fatigue; Female; Humans; Sirolimus

2014
Aromatase inhibitors in breast cancer prevention.
    The Annals of pharmacotherapy, 2014, Volume: 48, Issue:12

    Topics: Anastrozole; Androstadienes; Anticarcinogenic Agents; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Letrozole; Neoplasm Invasiveness; Nitriles; Postmenopause; Risk; Triazoles

2014
Interaction of Salicylates and the Other Nonsteroidal Anti-Inflammatory Agents With Breast Cancer Endocrine Treatment: Systematic Review.
    American journal of clinical oncology, 2015, Volume: 38, Issue:6

    Topics: Androstadienes; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Aspirin; Breast Neoplasms; Celecoxib; Drug Synergism; Female; Humans; Salicylates; Tamoxifen

2015
A new era of improving progression-free survival with dual blockade in postmenopausal HR(+), HER2(-) advanced breast cancer.
    Cancer treatment reviews, 2015, Volume: 41, Issue:2

    Topics: Anastrozole; Androstadienes; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Bevacizumab; Biomarkers, Tumor; Breast Neoplasms; Clinical Trials as Topic; Disease-Free Survival; Estradiol; Everolimus; Female; Fulvestrant; Humans; Molecular Targeted Therapy; Nitriles; Patient Selection; Postmenopause; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Sirolimus; Treatment Failure; Treatment Outcome; Triazoles

2015
Evaluating the pharmacokinetics and pharmacodynamics of everolimus for treating breast cancer.
    Expert opinion on drug metabolism & toxicology, 2015, Volume: 11, Issue:5

    Topics: Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Drug Resistance, Neoplasm; Everolimus; Female; Humans; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; TOR Serine-Threonine Kinases

2015
Adjuvant systemic therapy in breast cancer: quo vadis?
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:8

    Topics: Androstadienes; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carboplatin; Chemotherapy, Adjuvant; Female; Humans; Lapatinib; Mastectomy; Paclitaxel; Patient Selection; Poly(ADP-ribose) Polymerase Inhibitors; Quinazolines; Tamoxifen; Trastuzumab; Triple Negative Breast Neoplasms

2015
Everolimus plus exemestane for the treatment of advanced breast cancer: a review of subanalyses from BOLERO-2.
    Neoplasia (New York, N.Y.), 2015, Volume: 17, Issue:3

    Topics: Age Factors; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials, Phase III as Topic; Everolimus; Female; Humans; Multicenter Studies as Topic; Neoplasm Staging; Randomized Controlled Trials as Topic; Treatment Outcome

2015
A network meta-analysis of everolimus plus exemestane versus chemotherapy in the first- and second-line treatment of estrogen receptor-positive metastatic breast cancer.
    Breast cancer research and treatment, 2015, Volume: 152, Issue:1

    Topics: Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Disease Progression; Everolimus; Female; Humans; Kaplan-Meier Estimate; Proportional Hazards Models; Randomized Controlled Trials as Topic; Receptors, Estrogen; Retreatment; Treatment Outcome

2015
Anti-Hormonal Therapies for Premenopausal Patients--What did we Learn from the TEXT/SOFT Trials?
    Reviews on recent clinical trials, 2015, Volume: 10, Issue:2

    Topics: Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Drug Therapy, Combination; Estrogen Antagonists; Female; Humans; Multicenter Studies as Topic; Ovary; Premenopause; Randomized Controlled Trials as Topic; Tamoxifen; Triptorelin Pamoate

2015
Enhancing Endocrine Therapy for Hormone Receptor-Positive Advanced Breast Cancer: Cotargeting Signaling Pathways.
    Journal of the National Cancer Institute, 2015, Volume: 107, Issue:10

    Topics: Adult; Aged; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Cell Proliferation; Cell Survival; Drug Resistance, Neoplasm; Everolimus; Female; Humans; Letrozole; Middle Aged; Molecular Targeted Therapy; Nitriles; Piperazines; Protein Kinase Inhibitors; Pyridines; Receptors, Estrogen; Research Design; Signal Transduction; Triazoles

2015
Are we ready to change clinical practice after the 'soft and text' results?
    Future oncology (London, England), 2015, Volume: 11, Issue:21

    Topics: Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials, Phase III as Topic; Disease Management; Female; Gonadotropin-Releasing Hormone; Humans; Multicenter Studies as Topic; Practice Patterns, Physicians'; Risk Factors; Treatment Outcome

2015
Better Together: Targeted Combination Therapies in Breast Cancer.
    Seminars in oncology, 2015, Volume: 42, Issue:6

    Topics: Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Drug Resistance, Neoplasm; Everolimus; Female; Humans; Lapatinib; Letrozole; Molecular Targeted Therapy; Nitriles; Piperazines; Protein Kinase Inhibitors; Pyridines; Quinazolines; Receptor, ErbB-2; Trastuzumab; Triazoles

2015
[New options in adjuvant endocrine therapy in breast cancer].
    Bulletin du cancer, 2016, Volume: 103, Issue:1

    Topics: Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Estrogen Antagonists; Estrogens; Female; Humans; Menopause; Receptors, Estrogen; Tamoxifen; Time Factors

2016
[Hormonotherapy for breast cancer prevention: What about women with genetic predisposition to breast cancer?].
    Bulletin du cancer, 2016, Volume: 103, Issue:3

    Topics: Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Endometrial Neoplasms; Female; Genes, BRCA1; Genes, BRCA2; Genetic Predisposition to Disease; Humans; Mastectomy; Mutation; Nitriles; Prophylactic Surgical Procedures; Raloxifene Hydrochloride; Tamoxifen; Triazoles

2016
Alternate dosing schedules for cancer chemopreventive agents.
    Seminars in oncology, 2016, Volume: 43, Issue:1

    Topics: Administration, Oral; Androstadienes; Anticarcinogenic Agents; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Breast Neoplasms; Chemoprevention; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Ki-67 Antigen; Preoperative Care; Risk Factors; Tamoxifen

2016
Network Meta-Analysis Comparing Overall Survival for Fulvestrant 500 mg Versus Alternative Therapies for Treatment of Postmenopausal, Estrogen Receptor-Positive Advanced Breast Cancer Following Failure on Prior Endocrine Therapy.
    Clinical breast cancer, 2016, Volume: 16, Issue:3

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Disease-Free Survival; Dose-Response Relationship, Drug; Estradiol; Everolimus; Female; Fulvestrant; Humans; Letrozole; Megestrol Acetate; Network Meta-Analysis; Nitriles; Postmenopause; Receptors, Estrogen; Treatment Outcome; Triazoles

2016
Unravelling exemestane: From biology to clinical prospects.
    The Journal of steroid biochemistry and molecular biology, 2016, Volume: 163

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Apoptosis; Aromatase Inhibitors; Autophagy; Biotransformation; Breast Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Clinical Trials as Topic; Drug Resistance, Neoplasm; Female; Humans; Nitriles; Tamoxifen; Triazoles

2016
Endocrine therapy for hormone treatment-naïve advanced breast cancer.
    Breast (Edinburgh, Scotland), 2016, Volume: 28

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Breast Neoplasms; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Estradiol; Female; Fulvestrant; Humans; Letrozole; Nitriles; Piperazines; Pyridines; Randomized Controlled Trials as Topic; Tamoxifen; Triazoles

2016
Endocrine treatment in breast cancer: Cure, resistance and beyond.
    Cancer treatment reviews, 2016, Volume: 50

    Topics: Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Drug Resistance, Neoplasm; Estradiol; Everolimus; Female; Fulvestrant; Humans; Molecular Targeted Therapy; Neoadjuvant Therapy; Piperazines; Pyridines; Receptors, Estrogen; Tamoxifen

2016
Mechanism of drug resistance in relation to site of metastasis: Meta-analyses of randomized controlled trials in advanced breast cancer according to anticancer strategy.
    Cancer treatment reviews, 2016, Volume: 50

    Topics: Anastrozole; Androstadienes; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Disease-Free Survival; Drug Resistance, Neoplasm; Estradiol; Everolimus; Female; Fulvestrant; Humans; Letrozole; Nitriles; Piperazines; Pyridines; Randomized Controlled Trials as Topic; Trastuzumab; Triazoles

2016
ADJUVANT (HORMONAL) THERAPY AS A CAUSE OF BONE LOSS IN PATIENTS WITH BREAST CANCER (REVIEW OF LITERATURE).
    Georgian medical news, 2017, Issue:262

    Topics: Anastrozole; Androstadienes; Aromatase Inhibitors; Bone Density; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Estrogen Antagonists; Female; Humans; Letrozole; Nitriles; Osteoporosis; Postmenopause; Premenopause; Selective Estrogen Receptor Modulators; Tamoxifen; Triazoles

2017
Experience with exemestane in the treatment of early and advanced breast cancer.
    Expert opinion on drug metabolism & toxicology, 2008, Volume: 4, Issue:7

    Topics: Androstadienes; Animals; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Neoplasm Metastasis

2008
[Adjuvant endocrine therapy in postmenopausal hormone-sensitive breast cancer: to start, to switch or to extend?].
    Magyar onkologia, 2008, Volume: 52, Issue:2

    Topics: Aged; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Drug Administration Schedule; Drug Resistance, Neoplasm; Estrogen Receptor Modulators; Female; Humans; Letrozole; Lymphatic Metastasis; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Quality of Life; Randomized Controlled Trials as Topic; Selective Estrogen Receptor Modulators; Tamoxifen; Treatment Outcome; Triazoles

2008
Exemestane: a review of its use in postmenopausal women with breast cancer.
    Drugs, 2009, Volume: 69, Issue:7

    Topics: Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Cost-Benefit Analysis; Female; Humans; Postmenopause

2009
Comparative review of anastrozole, letrozole and exemestane in the management of early breast cancer.
    Expert opinion on pharmacotherapy, 2009, Volume: 10, Issue:9

    Topics: Anastrozole; Androstadienes; Animals; Breast Neoplasms; Disease Management; Early Detection of Cancer; Female; Humans; Letrozole; Nitriles; Randomized Controlled Trials as Topic; Triazoles

2009
Exemestane as first-line therapy in postmenopausal women with recurrent or metastatic breast cancer.
    American journal of clinical oncology, 2010, Volume: 33, Issue:3

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Celecoxib; Estrogens; Female; Humans; Letrozole; Middle Aged; Multicenter Studies as Topic; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Pyrazoles; Randomized Controlled Trials as Topic; Recurrence; Salvage Therapy; Sulfonamides; Tamoxifen; Triazoles

2010
Systematic review of aromatase inhibitors in the first-line treatment for hormone sensitive advanced or metastatic breast cancer.
    Breast cancer research and treatment, 2010, Volume: 123, Issue:1

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Letrozole; Nitriles; Postmenopause; Randomized Controlled Trials as Topic; Triazoles

2010
Exemestane in postmenopausal women with early or advanced breast cancer: a review.
    Expert opinion on pharmacotherapy, 2010, Volume: 11, Issue:11

    Topics: Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Postmenopause

2010
Women and bone health: maximizing the benefits of aromatase inhibitor therapy.
    Oncology, 2010, Volume: 79, Issue:1-2

    Topics: Anastrozole; Androstadienes; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Bone Density; Bone Density Conservation Agents; Bone Remodeling; Breast Neoplasms; Colorectal Neoplasms; Denosumab; Diphosphonates; Female; Humans; Imidazoles; Letrozole; Nitriles; Osteoporosis; Osteoporosis, Postmenopausal; Randomized Controlled Trials as Topic; RANK Ligand; Secondary Prevention; Tamoxifen; Triazoles; Zoledronic Acid

2010
The effect of exemestane and tamoxifen on bone health within the Tamoxifen Exemestane Adjuvant Multinational (TEAM) trial: a meta-analysis of the US, German, Netherlands, and Belgium sub-studies.
    Journal of cancer research and clinical oncology, 2011, Volume: 137, Issue:6

    Topics: Androstadienes; Antineoplastic Agents; Belgium; Bone Density; Bone Remodeling; Breast Neoplasms; Female; Germany; Hip; Humans; Lumbar Vertebrae; Middle Aged; Netherlands; Randomized Controlled Trials as Topic; Tamoxifen; United States

2011
When to start an aromatase inhibitor: now or later?
    Journal of surgical oncology, 2011, Jun-01, Volume: 103, Issue:7

    Topics: Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Cost-Benefit Analysis; Drug Administration Schedule; Female; Humans; Letrozole; Neoadjuvant Therapy; Neoplasm Metastasis; Neoplasm Recurrence, Local; Nitriles; Randomized Controlled Trials as Topic; Risk Assessment; Risk Factors; Selective Estrogen Receptor Modulators; Tamoxifen; Triazoles

2011
Overview of adjuvant trials of aromatase inhibitors in early breast cancer.
    Steroids, 2011, Volume: 76, Issue:8

    Topics: Anastrozole; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Letrozole; Nitriles; Postmenopause; Randomized Controlled Trials as Topic; Receptors, Estrogen; Tamoxifen; Triazoles

2011
Drug safety evaluation of exemestane.
    Expert opinion on drug safety, 2011, Volume: 10, Issue:3

    Topics: Androstadienes; Animals; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Female; Humans

2011
Preventive therapy for breast cancer: a consensus statement.
    The Lancet. Oncology, 2011, Volume: 12, Issue:5

    Topics: Anastrozole; Androstadienes; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Consensus Development Conferences as Topic; Diphosphonates; Estrogen Receptor Modulators; Expert Testimony; Female; Fenretinide; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Metformin; Nitriles; Norpregnenes; Piperidines; Premenopause; Pyrrolidines; Raloxifene Hydrochloride; Retinoids; Selective Estrogen Receptor Modulators; Tamoxifen; Tetrahydronaphthalenes; Thiophenes; Triazoles

2011
Aromatase inhibitor-induced skin adverse reactions: exemestane-related cutaneous vasculitis.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2011, Volume: 25, Issue:5

    Topics: Aged, 80 and over; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Retrospective Studies; Vasculitis, Leukocytoclastic, Cutaneous

2011
[Aromatase inhibitors and arthralgia].
    Magyar onkologia, 2011, Volume: 55, Issue:1

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Arthralgia; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Female; Humans; Letrozole; Medication Adherence; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Quality of Life; Risk Factors; Triazoles

2011
Clinical and economic benefits of aromatase inhibitor therapy in early-stage breast cancer.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2011, Sep-15, Volume: 68, Issue:18

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Cost-Benefit Analysis; Female; Humans; Letrozole; Nitriles; Postmenopause; Survival Analysis; Triazoles

2011
Management of patients with metastatic breast cancer.
    Advances in therapy, 2011, Volume: 28 Suppl 6

    Topics: Adult; Age Factors; Aged; Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Disease Management; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Delivery Systems; Estradiol; Female; Fulvestrant; Humans; Letrozole; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Nitriles; Prognosis; Randomized Controlled Trials as Topic; Risk Assessment; Survival Analysis; Treatment Outcome; Triazoles

2011
Initialization of adjuvant hormonal treatment for breast cancer.
    Advances in therapy, 2011, Volume: 28 Suppl 6

    Topics: Adult; Age Factors; Aged; Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Early Detection of Cancer; Female; Humans; Mastectomy; Middle Aged; Neoplasm Staging; Nitriles; Postmenopause; Premenopause; Prognosis; Randomized Controlled Trials as Topic; Risk Assessment; Survival Analysis; Tamoxifen; Treatment Outcome; Triazoles

2011
Breast cancer chemoprevention.
    Expert review of anticancer therapy, 2012, Volume: 12, Issue:2

    Topics: Androstadienes; Animals; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemoprevention; Female; Humans; Raloxifene Hydrochloride; Randomized Controlled Trials as Topic; Tamoxifen

2012
Exemestane for breast cancer prevention: a critical shift?
    Cancer discovery, 2012, Volume: 2, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Anticarcinogenic Agents; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Middle Aged; Risk Factors

2012
Aromatase inhibitors in the treatment of elderly women with metastatic breast cancer.
    Breast (Edinburgh, Scotland), 2013, Volume: 22, Issue:2

    Topics: Aged, 80 and over; Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Comorbidity; Disease Management; Disease Progression; Drug Therapy, Combination; Female; Geriatric Assessment; Health Status; Humans; Letrozole; Life Expectancy; Nitriles; Prognosis; Quality of Life; Treatment Outcome; Triazoles

2013
Letrozole for the management of breast cancer.
    Expert review of anticancer therapy, 2002, Volume: 2, Issue:3

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Drug Tolerance; Estrogen Receptor Modulators; Estrogens; Female; Humans; Letrozole; Neoadjuvant Therapy; Nitriles; Postmenopause; Progestins; Receptors, Estrogen; Treatment Outcome; Triazoles

2002
Exemestane: a potent irreversible aromatase inactivator and a promising advance in breast cancer treatment.
    Expert review of anticancer therapy, 2002, Volume: 2, Issue:3

    Topics: Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Drug Tolerance; Female; Humans

2002
Recent advances in aromatase inhibitor therapy for breast cancer.
    Seminars in oncology, 2002, Volume: 29, Issue:3 Suppl 11

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Letrozole; Nitriles; Premenopause; Triazoles

2002
The role of aromasin in the hormonal therapy of breast cancer.
    Pathology oncology research : POR, 2002, Volume: 8, Issue:2

    Topics: Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Enzyme Inhibitors; Female; Humans

2002
Overview of the pharmacology of the aromatase inactivator exemestane.
    Breast cancer research and treatment, 2002, Volume: 74, Issue:2

    Topics: Adult; Aged; Androstadienes; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; Middle Aged; Postmenopause; Receptors, Estrogen

2002
The role of aromatase inactivators in the treatment of breast cancer.
    International journal of clinical oncology, 2002, Volume: 7, Issue:4

    Topics: Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Female; Humans

2002
New generation aromatase inhibitors--from the advanced to the adjuvant setting.
    Breast cancer research and treatment, 2002, Volume: 75 Suppl 1

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Enzyme Inhibitors; Female; Humans; Letrozole; Nitriles; Triazoles

2002
An overview of the pharmacology and pharmacokinetics of the newer generation aromatase inhibitors anastrozole, letrozole, and exemestane.
    Cancer, 2002, Nov-01, Volume: 95, Issue:9

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; Letrozole; Nitriles; Triazoles

2002
Exemestane: treatment of breast cancer with selective inactivation of aromatase.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2002, Nov-15, Volume: 59, Issue:22

    Topics: Androstadienes; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Drug Interactions; Female; Humans

2002
Pharmacology and pharmacokinetics of the newer generation aromatase inhibitors.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Volume: 9, Issue:1 Pt 2

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Female; Humans; Letrozole; Lipids; Nitriles; Postmenopause; Triazoles

2003
The current status of aromatase inhibitors in the management of breast cancer.
    The Surgical clinics of North America, 2003, Volume: 83, Issue:4

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; Letrozole; Nitriles; Triazoles

2003
Applicability of the intratumor aromatase preclinical model to predict clinical trial results with endocrine therapy.
    American journal of clinical oncology, 2003, Volume: 26, Issue:4

    Topics: Anastrozole; Androstadienes; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Enzyme Inhibitors; Estrogen Antagonists; Humans; Letrozole; Neoplasm Metastasis; Nitriles; Tamoxifen; Triazoles; Xenograft Model Antitumor Assays

2003
A comparison of the efficacy of aromatase inhibitors in second-line treatment of metastatic breast cancer.
    American journal of clinical oncology, 2003, Volume: 26, Issue:4

    Topics: Aminoglutethimide; Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Enzyme Inhibitors; Female; Humans; Letrozole; Megestrol Acetate; Neoplasm Metastasis; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Receptors, Estrogen; Tamoxifen; Triazoles

2003
[Perspectives for the hormonal therapy of breast cancer].
    Magyar onkologia, 2003, Volume: 47, Issue:2

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Breast Neoplasms; Enzyme Inhibitors; Estradiol; Estrogen Receptor Modulators; Female; Fulvestrant; Humans; Letrozole; Nitriles; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Toremifene; Triazoles

2003
The role of aromatase inhibitors in the treatment of metastatic breast cancer.
    Seminars in oncology, 2003, Volume: 30, Issue:4 Suppl 14

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Enzyme Inhibitors; Female; Humans; Letrozole; Neoplasm Metastasis; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Triazoles

2003
Aromatase inhibitors in breast cancer therapy.
    Clinical breast cancer, 2003, Volume: 4 Suppl 2

    Topics: Anastrozole; Androstadienes; Breast Neoplasms; Clinical Trials as Topic; Disease-Free Survival; Enzyme Inhibitors; Female; Humans; Letrozole; Neoplasm Recurrence, Local; Nitriles; Triazoles

2003
[Neoadjuvant endocrine therapy for breast cancer: an overview].
    Bulletin du cancer, 2004, Volume: 91, Issue:1

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Breast Neoplasms; Clinical Trials as Topic; Estrogen Antagonists; Female; Humans; Letrozole; Neoadjuvant Therapy; Nitriles; Tamoxifen; Triazoles

2004
Exemestane and aromatase inhibitors in the management of advanced breast cancer.
    Expert opinion on pharmacotherapy, 2004, Volume: 5, Issue:2

    Topics: Administration, Oral; Androstadienes; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; United Kingdom

2004
[Controversies in endocrine therapy for breast cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:2

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Enzyme Inhibitors; Estrogen Replacement Therapy; Female; Humans; Letrozole; Mastectomy, Segmental; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Randomized Controlled Trials as Topic; Receptors, Estrogen; Receptors, Progesterone; Risk Factors; Tamoxifen; Triazoles

2004
Aromatase inhibitors for breast cancer in postmenopausal women.
    The oncologist, 2004, Volume: 9, Issue:2

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Enzyme Inhibitors; Female; Humans; Letrozole; Megestrol Acetate; Nitriles; Postmenopause; Receptors, Estrogen; Tamoxifen; Triazoles

2004
Aromatase inhibitors: current indications and future prospects for treatment of postmenopausal breast cancer.
    Journal of the American Geriatrics Society, 2004, Volume: 52, Issue:4

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Drug Approval; Drug Interactions; Economics, Pharmaceutical; Female; Forecasting; Geriatrics; Humans; Letrozole; Neoadjuvant Therapy; Nitriles; Patient Selection; Postmenopause; Practice Patterns, Physicians'; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Tamoxifen; Treatment Outcome; Triazoles; United States; United States Food and Drug Administration

2004
Aromatase inhibitors in the adjuvant setting: bringing the gold to a standard?
    Cancer treatment reviews, 2004, Volume: 30, Issue:4

    Topics: Aged; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Enzyme Inhibitors; Female; Humans; Letrozole; Middle Aged; Nitriles; Postmenopause; Survival Analysis; Tamoxifen; Treatment Outcome; Triazoles

2004
Aromatase inhibition in the treatment of advanced breast cancer: is there a relationship between potency and clinical efficacy?
    British journal of cancer, 2004, May-04, Volume: 90, Issue:9

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Letrozole; Middle Aged; Nitriles; Randomized Controlled Trials as Topic; Tamoxifen; Triazoles

2004
[Aromatase inhibitors in the adjuvant therapy of breast carcinomas].
    Therapeutische Umschau. Revue therapeutique, 2004, Volume: 61, Issue:6

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Female; Humans; Letrozole; Neoplasm Recurrence, Local; Nitriles; Patient Care Management; Practice Guidelines as Topic; Practice Patterns, Physicians'; Tamoxifen; Treatment Outcome; Triazoles

2004
Current developments in hormonal therapy of breast cancer.
    Clinical breast cancer, 2004, Volume: 5 Suppl 1

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Letrozole; Nitriles; Tamoxifen; Triazoles

2004
The role of aromatase inhibitors in the adjuvant treatment of breast carcinoma: the M. D. Anderson Cancer Center evidence-based approach.
    Cancer, 2004, Oct-01, Volume: 101, Issue:7

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Double-Blind Method; Enzyme Inhibitors; Evidence-Based Medicine; Female; Humans; Letrozole; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Prospective Studies; Tamoxifen; Triazoles

2004
Role of aromatase inhibitors in the treatment of breast cancer.
    Clinical therapeutics, 2004, Volume: 26, Issue:8

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; Letrozole; Nitriles; Triazoles

2004
[Tamoxifen and aromatase inhibitors in the treatment of breast cancer in menopausal women: pharmacological and clinical aspects].
    Bulletin du cancer, 2004, Volume: 91, Issue:12

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Estrogen Antagonists; Female; Humans; Letrozole; Menopause; Neoplasms, Hormone-Dependent; Nitriles; Selective Estrogen Receptor Modulators; Tamoxifen; Triazoles

2004
Aromatase inhibitors and breast cancer: time for a change?
    International journal of clinical practice, 2004, Volume: 58, Issue:12

    Topics: Aged; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Cost-Benefit Analysis; Female; Humans; Letrozole; Multicenter Studies as Topic; Nitriles; Randomized Controlled Trials as Topic; Risk Factors; Tamoxifen; Treatment Outcome; Triazoles

2004
Endocrine treatment options for advanced breast cancer--the role of fulvestrant.
    European journal of cancer (Oxford, England : 1990), 2005, Volume: 41, Issue:3

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Gefitinib; Humans; Nitriles; Postmenopause; Quinazolines; Tamoxifen; Treatment Outcome; Triazoles

2005
Exemestane for breast cancer prevention: a feasible strategy?
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Jan-15, Volume: 11, Issue:2 Pt 2

    Topics: Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Female; Humans; Postmenopause; Risk Factors

2005
Using aromatase inhibitors in the neoadjuvant setting: evolution or revolution?
    Cancer treatment reviews, 2005, Volume: 31, Issue:1

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Biomarkers, Tumor; Breast Neoplasms; Evidence-Based Medicine; Female; Humans; Letrozole; Mastectomy, Segmental; Neoadjuvant Therapy; Nitriles; Randomized Controlled Trials as Topic; Receptors, Estrogen; Survival Analysis; Tamoxifen; Treatment Outcome; Triazoles

2005
Adjuvant use of aromatase inhibitors in postmenopausal women with breast cancer.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2005, Feb-01, Volume: 62, Issue:3

    Topics: Anastrozole; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Female; Humans; Middle Aged; Nitriles; Postmenopause; Tamoxifen; Triazoles

2005
Aromatase inhibitors in advanced breast cancer.
    Seminars in oncology, 2004, Volume: 31, Issue:6 Suppl 12

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Letrozole; Neoplasm Metastasis; Nitriles; Postmenopause; Randomized Controlled Trials as Topic; Triazoles

2004
Aromatase inhibition: translation into a successful therapeutic approach.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Apr-15, Volume: 11, Issue:8

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Estrogens; Female; Humans; Letrozole; Molecular Structure; Nitriles; Triazoles

2005
[Aromatase inhibitors in adjuvant setting in breast cancer].
    Bulletin du cancer, 2004, Dec-01, Volume: 91 Suppl 4

    Topics: Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Letrozole; Menopause; Nitriles; Triazoles

2004
A comparison of fulvestrant and the third-generation aromatase inhibitors in the second-line treatment of postmenopausal women with advanced breast cancer.
    Cancer treatment reviews, 2005, Volume: 31, Issue:4

    Topics: Aged; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials, Phase III as Topic; Drug Resistance, Neoplasm; Estradiol; Female; Fulvestrant; Humans; Letrozole; Middle Aged; Nitriles; Postmenopause; Tamoxifen; Triazoles

2005
Aromatase inhibitors for therapy of advanced breast cancer.
    The Journal of steroid biochemistry and molecular biology, 2005, Volume: 95, Issue:1-5

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials, Phase III as Topic; Drug Evaluation; Female; Humans; Letrozole; Megestrol Acetate; Nitriles; Postmenopause; Tamoxifen; Treatment Outcome; Triazoles

2005
Recent advances in the use of aromatase inhibitors for women with postmenopausal breast cancer.
    The journal of the British Menopause Society, 2005, Volume: 11, Issue:3

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Female; Humans; Letrozole; Nitriles; Postmenopause; Triazoles

2005
Chemoprevention in breast cancer.
    Clinical advances in hematology & oncology : H&O, 2005, Volume: 3, Issue:7

    Topics: Age Factors; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Carcinoma in Situ; Carcinoma, Lobular; Female; Humans; Randomized Controlled Trials as Topic; Risk Factors; Tamoxifen

2005
A review of exemestane in the management of breast cancer.
    Expert opinion on pharmacotherapy, 2005, Volume: 6, Issue:13

    Topics: Administration, Oral; Androstadienes; Animals; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Megestrol Acetate; Multicenter Studies as Topic; Neoadjuvant Therapy; Randomized Controlled Trials as Topic; Tamoxifen; Treatment Outcome

2005
Comparative assessment of lipid effects of endocrine therapy for breast cancer: implications for cardiovascular disease prevention in postmenopausal women.
    Breast (Edinburgh, Scotland), 2006, Volume: 15, Issue:3

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, LDL; Estradiol; Female; Fulvestrant; Hormone Replacement Therapy; Humans; Lipids; Middle Aged; Nitriles; Osteoporosis, Postmenopausal; Risk Factors; Tamoxifen; Triazoles; Triglycerides

2006
Life following aromatase inhibitors--where now for endocrine sequencing?
    Breast cancer research and treatment, 2005, Volume: 93 Suppl 1

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Drug Resistance, Neoplasm; Estradiol; Estrogen Receptor Modulators; Female; Fulvestrant; Humans; Nitriles; Triazoles

2005
Fulvestrant, a new treatment option for advanced breast cancer: tolerability versus existing agents.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2006, Volume: 17, Issue:2

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Endometrial Neoplasms; Estradiol; Female; Fulvestrant; Humans; Joint Diseases; Nitriles; Postmenopause; Randomized Controlled Trials as Topic; Tamoxifen; Triazoles

2006
Defining the roles of aromatase inhibitors in the adjuvant treatment of early-stage breast cancer.
    Clinical breast cancer, 2005, Volume: 6, Issue:4

    Topics: Anastrozole; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Female; Humans; Neoplasm Staging; Nitriles; Research Design; Tamoxifen; Triazoles

2005
Benefit with aromatase inhibitors in the adjuvant setting for postmenopausal women with breast cancer.
    MedGenMed : Medscape general medicine, 2005, Aug-24, Volume: 7, Issue:3

    Topics: Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Female; Humans; Letrozole; Nitriles; Postmenopause; Triazoles

2005
Adjuvant aromatase inhibitor therapy for early breast cancer: A review of the most recent data.
    Journal of surgical oncology, 2006, Jun-01, Volume: 93, Issue:7

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Female; Humans; Letrozole; Nitriles; Postmenopause; Randomized Controlled Trials as Topic; Tamoxifen; Triazoles

2006
Pre-menopausal breast cancer and aromatase inhibitors: Treating a new generation of women.
    Breast cancer research and treatment, 2006, Volume: 99, Issue:3

    Topics: Adult; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Drug Therapy; Estrogens; Female; Humans; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Premenopause; Randomized Controlled Trials as Topic; Treatment Outcome; Triazoles

2006
The evolving role of exemestane in the management of breast cancer.
    British journal of hospital medicine (London, England : 2005), 2006, Volume: 67, Issue:8

    Topics: Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Drug Evaluation; Female; Humans; Treatment Outcome

2006
Update on the use of aromatase inhibitors in breast cancer.
    Expert opinion on pharmacotherapy, 2006, Volume: 7, Issue:14

    Topics: Anastrozole; Androstadienes; Animals; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Letrozole; Nitriles; Postmenopause; Randomized Controlled Trials as Topic; Triazoles

2006
Aromatase inhibitors and bone health in women with breast cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Nov-20, Volume: 24, Issue:33

    Topics: Absorptiometry, Photon; Algorithms; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Bone Density; Bone Remodeling; Breast Neoplasms; Diphosphonates; Female; Fractures, Bone; Humans; Life Style; Neoplasms, Hormone-Dependent; Nitriles; Osteoporosis, Postmenopausal; Population Surveillance; Risk Factors; Triazoles

2006
Adjuvant therapy for patients who have node-positive breast cancer.
    Advances in surgery, 2006, Volume: 40

    Topics: Adult; Anastrozole; Androstadienes; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Lymphatic Metastasis; Middle Aged; Nitriles; Postmenopause; Radiotherapy, Adjuvant; Randomized Controlled Trials as Topic; Tamoxifen; Treatment Outcome; Triazoles

2006
Initial versus sequential adjuvant aromatase inhibitor therapy: a review of the current data.
    Current medical research and opinion, 2006, Volume: 22, Issue:12

    Topics: Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Cost-Benefit Analysis; Female; Health Care Costs; Humans; Nitriles; Quality of Life; Randomized Controlled Trials as Topic; Tamoxifen; Triazoles

2006
[Optimal adjuvant hormone therapy in postmenopausal women with hormone-sensitive mammary carcinoma: tamoxifen and the aromatase inhibitors anastrozole, exemestane and letrozole].
    Nederlands tijdschrift voor geneeskunde, 2006, Dec-30, Volume: 150, Issue:52

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Carcinoma; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Humans; Letrozole; Nitriles; Postmenopause; Tamoxifen; Treatment Outcome; Triazoles

2006
[Advancement in endocrine therapy for breast cancer].
    Ai zheng = Aizheng = Chinese journal of cancer, 2007, Volume: 26, Issue:4

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Letrozole; Nitriles; Selective Estrogen Receptor Modulators; Tamoxifen; Triazoles

2007
Hormonal therapies for early breast cancer: systematic review and economic evaluation.
    Health technology assessment (Winchester, England), 2007, Volume: 11, Issue:26

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Cost-Benefit Analysis; Drug Administration Schedule; Female; Humans; Letrozole; Neoplasm Recurrence, Local; Nitriles; Quality-Adjusted Life Years; Survival Analysis; Tamoxifen; Time Factors; Triazoles

2007
Aromatase inhibitors and musculoskeletal pain in patients with breast cancer.
    Clinical journal of oncology nursing, 2007, Volume: 11, Issue:3

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Drug Monitoring; Female; Humans; Musculoskeletal Diseases; Nitriles; Nurse's Role; Nursing Assessment; Nursing Research; Oncology Nursing; Pain; Pain Management; Pain Measurement; Patient Care Planning; Patient Education as Topic; Patient Selection; Postmenopause; Quality of Life; Receptors, Estrogen; Treatment Outcome; Triazoles

2007
[Antiestrogen treatment in postmenopausal patients with metastatic breast cancer].
    Ugeskrift for laeger, 2007, Sep-10, Volume: 169, Issue:37

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Humans; Letrozole; Nitriles; Postmenopause; Prognosis; Selective Estrogen Receptor Modulators; Tamoxifen; Treatment Outcome; Triazoles

2007
The what, why and how of aromatase inhibitors: hormonal agents for treatment and prevention of breast cancer.
    International journal of clinical practice, 2007, Volume: 61, Issue:12

    Topics: Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Cardiovascular Diseases; Chemotherapy, Adjuvant; Drug Resistance; Female; Humans; Letrozole; Musculoskeletal Diseases; Nitriles; Postmenopause; Premenopause; Tamoxifen; Thromboembolism; Triazoles

2007
Safety of aromatase inhibitors in the adjuvant setting.
    Breast cancer research and treatment, 2007, Volume: 105 Suppl 1

    Topics: Anastrozole; Androstadienes; Animals; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Cardiovascular Diseases; Causality; Chemotherapy, Adjuvant; Comorbidity; Estrogen Receptor Modulators; Female; Hot Flashes; Humans; Incidence; Letrozole; Neoadjuvant Therapy; Neoplasms, Hormone-Dependent; Neoplasms, Second Primary; Nitriles; Osteoporosis; Rats; Survival Analysis; Tamoxifen; Triazoles

2007
Reducing the risk for breast cancer recurrence after completion of tamoxifen treatment in postmenopausal women.
    Clinical therapeutics, 2007, Volume: 29, Issue:8

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Drug Administration Schedule; Female; Humans; Letrozole; Nitriles; Postmenopause; Practice Guidelines as Topic; Quality of Life; Risk Assessment; Secondary Prevention; Tamoxifen; Treatment Outcome; Triazoles

2007
Aromatase inhibitors: past, present and future in breast cancer therapy.
    Medical oncology (Northwood, London, England), 2008, Volume: 25, Issue:2

    Topics: Aminoglutethimide; Androstadienes; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Fadrozole; Female; Humans; Letrozole; Nitriles; Triazoles

2008
To switch or not to switch: should the updated Intergroup Exemestane Study alter our decision?
    Expert review of anticancer therapy, 2008, Volume: 8, Issue:1

    Topics: Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Female; Humans; Neoplasms, Hormone-Dependent; Selective Estrogen Receptor Modulators; Tamoxifen

2008
Aromatase inhibitors in adjuvant therapy for hormone receptor positive breast cancer: a systematic review.
    Cancer treatment reviews, 2008, Volume: 34, Issue:2

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Humans; Letrozole; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Randomized Controlled Trials as Topic; Survival Analysis; Tamoxifen; Time Factors; Treatment Outcome; Triazoles

2008
The impact of adjuvant endocrine therapy on reducing the risk of distant metastases in hormone-responsive breast cancer.
    Breast (Edinburgh, Scotland), 2008, Volume: 17 Suppl 1

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials, Phase III as Topic; Disease-Free Survival; Evidence-Based Medicine; Letrozole; Neoplasm Metastasis; Neoplasm Staging; Nitriles; Quality of Life; Randomized Controlled Trials as Topic; Tamoxifen; Treatment Outcome; Triazoles

2008
Statistical analysis in cancer clinical trials.
    Anti-cancer drugs, 2008, Volume: 19 Suppl 1

    Topics: Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Data Interpretation, Statistical; Disease-Free Survival; Drug Administration Schedule; Female; Humans; Postmenopause; Selective Estrogen Receptor Modulators; Tamoxifen

2008
Fulvestrant: expanding the endocrine treatment options for patients with hormone receptor-positive advanced breast cancer.
    Breast (Edinburgh, Scotland), 2008, Volume: 17 Suppl 3

    Topics: Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Estradiol; Estrogen Antagonists; Estrogen Receptor Modulators; Female; Fulvestrant; Humans; Randomized Controlled Trials as Topic; Receptors, Estrogen

2008
Aromatase inhibitors in early breast-cancer treatment: The story so far.
    Breast (Edinburgh, Scotland), 2008, Volume: 17 Suppl 3

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Female; Humans; Letrozole; Nitriles; Triazoles

2008
The role of endocrine therapies in reducing risk of recurrence in postmenopausal women with hormone receptor-positive breast cancer.
    European journal of oncology nursing : the official journal of European Oncology Nursing Society, 2008, Volume: 12, Issue:3

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Humans; Letrozole; Neoplasm Recurrence, Local; Nitriles; Nurse Clinicians; Nurse Practitioners; Nurse's Role; Oncology Nursing; Patient Education as Topic; Patient Selection; Postmenopause; Receptors, Estrogen; Risk Factors; Tamoxifen; Time Factors; Treatment Outcome; Triazoles

2008
Neoadjuvant endocrine therapy for breast cancer: past, present and future.
    Anti-cancer drugs, 2008, Volume: 19, Issue:4

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Female; Forecasting; Humans; Letrozole; Neoadjuvant Therapy; Neoplasms, Hormone-Dependent; Nitriles; Patient Selection; Postmenopause; Tamoxifen; Triazoles

2008
Targeting breast cancer with hormonal treatment options.
    The Nurse practitioner, 2008, Volume: 33, Issue:5

    Topics: Aftercare; Ambulatory Care; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Estrogen Receptor Modulators; Humans; Information Services; Internet; Letrozole; Nitriles; Nurse Practitioners; Patient Selection; Postmenopause; Practice Guidelines as Topic; Receptors, Estrogen; Tamoxifen; Treatment Outcome; Triazoles

2008
The emerging role of aromatase inhibitors in the adjuvant management of breast cancer.
    Reviews on recent clinical trials, 2006, Volume: 1, Issue:3

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Drug Therapy, Combination; Humans; Letrozole; Neoplasm Recurrence, Local; Nitriles; Randomized Controlled Trials as Topic; Tamoxifen; Treatment Outcome; Triazoles

2006
Aromatase inhibitors for breast cancer: proven efficacy across the spectrum of disease.
    Clinical breast cancer, 2008, Volume: 8, Issue:1

    Topics: Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Letrozole; Neoadjuvant Therapy; Neoplasm Staging; Nitriles; Tamoxifen; Treatment Outcome; Triazoles

2008
Exemestane experience in breast cancer treatment.
    The Journal of steroid biochemistry and molecular biology, 1997, Volume: 61, Issue:3-6

    Topics: Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Enzyme Inhibitors; Female; Humans; Treatment Outcome

1997
Pharmacological profiles of exemestane and formestane, steroidal aromatase inhibitors used for treatment of postmenopausal breast cancer.
    Breast cancer research and treatment, 1998, Volume: 49 Suppl 1

    Topics: Androstadienes; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; Neoplasms, Hormone-Dependent; Postmenopause

1998
New aromatase inhibitors for the treatment of advanced breast cancer in postmenopausal women.
    The Netherlands journal of medicine, 1999, Volume: 55, Issue:2

    Topics: Aminoglutethimide; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials, Phase III as Topic; Female; Humans; Letrozole; Megestrol Acetate; Nitriles; Postmenopause; Triazoles

1999
Exemestane.
    Drugs, 1999, Volume: 58, Issue:4

    Topics: Androstadienes; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Enzyme Inhibitors; Female; Humans; Postmenopause

1999
[Aromatase inhibitors].
    Bulletin du cancer, 1999, Volume: 86, Issue:10

    Topics: Aminoglutethimide; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Estrogen Antagonists; Estrone; Female; Humans; Letrozole; Nitriles; Triazoles

1999
Use of aromatase inhibitors in breast carcinoma.
    Endocrine-related cancer, 1999, Volume: 6, Issue:1

    Topics: Adult; Aminoglutethimide; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Drug Design; Drug Interactions; Drug Resistance, Neoplasm; Enzyme Inhibitors; Estrogens; Female; Humans; Letrozole; Middle Aged; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Premenopause; Tamoxifen; Triazoles

1999
Steroidal aromatase inhibitors in elderly patients.
    Critical reviews in oncology/hematology, 2000, Volume: 33, Issue:2

    Topics: Aged; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; Letrozole; Nitriles; Triazoles

2000
Exemestane: a review of its use in postmenopausal women with advanced breast cancer.
    Drugs, 2000, Volume: 59, Issue:6

    Topics: Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; Postmenopause; Quality of Life

2000
[Aromatase inhibitors for treatment of advanced breast cancers].
    Nihon rinsho. Japanese journal of clinical medicine, 2000, Volume: 58 Suppl

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Estrogen Antagonists; Fadrozole; Female; Humans; Letrozole; Nitriles; Treatment Outcome; Triazoles

2000
New aromatase inhibitors in the treatment of advanced breast cancer.
    International journal of oncology, 2000, Volume: 17, Issue:5

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Double-Blind Method; Enzyme Inhibitors; Estrogens; Female; Humans; Letrozole; Multicenter Studies as Topic; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Randomized Controlled Trials as Topic; Triazoles

2000
Irreversible aromatase inactivation: treatment for breast cancer.
    Hospital medicine (London, England : 1998), 2000, Volume: 61, Issue:9

    Topics: Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; Randomized Controlled Trials as Topic

2000
Pharmacology and clinical experience with exemestane.
    Expert opinion on investigational drugs, 2000, Volume: 9, Issue:8

    Topics: Androstadienes; Animals; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Estrogen Antagonists; Estrogens; Humans

2000
Exemestane in advanced breast cancer.
    Anti-cancer drugs, 2000, Volume: 11, Issue:8

    Topics: Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Drug Tolerance; Enzyme Inhibitors; Female; Humans; Postmenopause

2000
Survival in patients with metastatic breast cancer: analysis of randomized studies comparing oral aromatase inhibitors versus megestrol.
    Anti-cancer drugs, 2000, Volume: 11, Issue:9

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; Letrozole; Megestrol; Neoplasm Metastasis; Nitriles; Proportional Hazards Models; Randomized Controlled Trials as Topic; Survival Analysis; Triazoles

2000
[Aromatase inhibitors: a review of clinical trials].
    Bulletin du cancer, 2000, Volume: 87 Spec No

    Topics: Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Enzyme Inhibitors; Female; Humans; Letrozole; Nitriles; Randomized Controlled Trials as Topic; Triazoles

2000
Adjuvant exemestane therapy after 5 years of tamoxifen: rationale for the NSABP B-33 trial.
    Oncology (Williston Park, N.Y.), 2001, Volume: 15, Issue:5 Suppl 7

    Topics: Androstadienes; Breast Neoplasms; Female; Humans; Meta-Analysis as Topic; Tamoxifen; Time Factors

2001
Nonsteroidal and steroidal aromatase inhibitors in breast cancer.
    Oncology (Williston Park, N.Y.), 2001, Volume: 15, Issue:8

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Enzyme Inhibitors; Female; Humans; Letrozole; Neoplasms, Hormone-Dependent; Nitriles; Triazoles

2001
Advances in aromatase inhibition: clinical efficacy and tolerability in the treatment of breast cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:9

    Topics: Anastrozole; Androstadienes; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Fadrozole; Female; Headache; Humans; Letrozole; Nausea; Nitriles; Treatment Outcome; Triazoles; Vomiting

2001
Role of anti-aromatase agents in postmenopausal advanced breast cancer.
    Cancer chemotherapy and pharmacology, 2001, Volume: 48, Issue:4

    Topics: Aged; Anastrozole; Androstadienes; Antineoplastic Agents, Phytogenic; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; Letrozole; Middle Aged; Nitriles; Postmenopause; Receptors, Estrogen; Tamoxifen; Triazoles

2001
Third-generation aromatase inhibitors in the treatment of advanced breast cancer.
    Breast cancer (Tokyo, Japan), 2001, Volume: 8, Issue:4

    Topics: Adult; Aged; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Humans; Letrozole; Mastectomy; Middle Aged; Neoplasm Staging; Nitriles; Randomized Controlled Trials as Topic; Tamoxifen; Treatment Outcome; Triazoles

2001
Aromatase and aromatase inhibitors.
    Breast cancer (Tokyo, Japan), 2001, Volume: 8, Issue:4

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials, Phase III as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Enzyme Inhibitors; Female; Follow-Up Studies; Humans; Letrozole; Nitriles; Survival Analysis; Treatment Outcome; Triazoles

2001
A summary of second-line randomized studies of aromatase inhibitors.
    The Journal of steroid biochemistry and molecular biology, 2001, Volume: 79, Issue:1-5

    Topics: Aminoglutethimide; Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Drug Tolerance; Enzyme Inhibitors; Estrogen Receptor Modulators; Fadrozole; Female; Humans; Letrozole; Megestrol Acetate; Neoplasms, Hormone-Dependent; Nitriles; Randomized Controlled Trials as Topic; Tamoxifen; Triazoles

2001
Exemestane: a novel aromatase inactivator for breast cancer.
    Clinical breast cancer, 2000, Volume: 1, Issue:3

    Topics: Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Enzyme Inhibitors; Female; Humans

2000
Are differences in the available aromatase inhibitors and inactivators significant?
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:12 Suppl

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Enzyme Inhibitors; Female; Humans; Letrozole; Nitriles; Triazoles

2001
Preliminary data from ongoing adjuvant aromatase inhibitor trials.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:12 Suppl

    Topics: Anastrozole; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Enzyme Inhibitors; Estrogen Antagonists; Female; Humans; Letrozole; Neoadjuvant Therapy; Neoplasms, Hormone-Dependent; Nitriles; Tamoxifen; Triazoles

2001
Exemestane in breast cancer: current status and future directions.
    Clinical breast cancer, 2000, Volume: 1 Suppl 1

    Topics: Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Disease Progression; Female; Humans; Survival Analysis

2000
Current status and future potential role of exemestane in the treatment of early and advanced breast cancer (Review).
    International journal of oncology, 2002, Volume: 20, Issue:6

    Topics: Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Enzyme Inhibitors; Female; Humans; Neoplasm Metastasis

2002
Antiaromatase agents: evolving role in adjuvant therapy.
    Clinical breast cancer, 2002, Volume: 3, Issue:1

    Topics: Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Enzyme Inhibitors; Female; Humans; Letrozole; Nitriles; Tamoxifen; Triazoles

2002
[The role of aromatase inhibitors in the treatment of breast neoplasms. An evaluation of clinical efficacy and the tolerability profile].
    Minerva ginecologica, 2002, Volume: 54, Issue:2

    Topics: Adult; Aminoglutethimide; Anastrozole; Androstadienes; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Enzyme Inhibitors; Female; Follow-Up Studies; Forecasting; Humans; Letrozole; Middle Aged; Nitriles; Randomized Controlled Trials as Topic; Selective Estrogen Receptor Modulators; Tamoxifen; Time Factors; Triazoles

2002
Exemestane, a new steroidal aromatase inhibitor of clinical relevance.
    Biochimica et biophysica acta, 2002, Jul-18, Volume: 1587, Issue:2-3

    Topics: Androstadienes; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Estrogen Receptor Modulators; Estrogens; Female; Humans; Neoplasms, Hormone-Dependent

2002

Trials

227 trial(s) available for aromasil and Breast Neoplasms

ArticleYear
Phase 1 trial of entinostat as monotherapy and combined with exemestane in Japanese patients with hormone receptor-positive advanced breast cancer.
    BMC cancer, 2021, Nov-24, Volume: 21, Issue:1

    Topics: Acetylation; Aged; Androstadienes; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Benzamides; Breast Neoplasms; Female; Histone Deacetylase Inhibitors; Humans; Hypophosphatemia; Japan; Lymphocyte Activation; Middle Aged; Nausea; Platelet Count; Progression-Free Survival; Pyridines

2021
A Phase Ib Dose Escalation Trial of RO4929097 (a γ-secretase inhibitor) in Combination with Exemestane in Patients with ER + Metastatic Breast Cancer (MBC).
    Clinical breast cancer, 2022, Volume: 22, Issue:2

    Topics: Aged; Androstadienes; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzazepines; Breast Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorocarbons; Humans; Maximum Tolerated Dose; Middle Aged; Neoplasm Metastasis; Receptor, Notch3; Receptors, Notch

2022
Efficacy and exploratory biomarker analysis of entinostat plus exemestane in advanced or recurrent breast cancer: phase II randomized controlled trial.
    Japanese journal of clinical oncology, 2023, Jan-06, Volume: 53, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Double-Blind Method; Estrogen Receptor alpha; Female; Humans; Lysine; Neoplasm Recurrence, Local; Receptors, Estrogen

2023
Local-Regional Recurrence After Neoadjuvant Endocrine Therapy: Data from ACOSOG Z1031 (Alliance), a Randomized Phase 2 Neoadjuvant Comparison Between Letrozole, Anastrozole, and Exemestane for Postmenopausal Women with Estrogen Receptor-Positive Clinical
    Annals of surgical oncology, 2023, Volume: 30, Issue:4

    Topics: Anastrozole; Breast Neoplasms; Female; Humans; Ki-67 Antigen; Letrozole; Mastectomy; Neoadjuvant Therapy; Postmenopause; Receptors, Estrogen

2023
Clinical efficacy of fulvestrant versus exemestane as first-line therapies for Chinese postmenopausal oestrogen-receptor positive /human epidermal growth factor receptor 2 -advanced breast cancer (FRIEND study).
    European journal of cancer (Oxford, England : 1990), 2023, Volume: 184

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; East Asian People; Estrogens; Female; Fulvestrant; Humans; Postmenopause; Progression-Free Survival; Receptor, ErbB-2; Receptors, Estrogen

2023
XENERA-1: a randomised double-blind Phase II trial of xentuzumab in combination with everolimus and exemestane versus everolimus and exemestane in patients with hormone receptor-positive/HER2-negative metastatic breast cancer and non-visceral disease.
    Breast cancer research : BCR, 2023, 06-12, Volume: 25, Issue:1

    Topics: Androstadienes; Breast Neoplasms; Everolimus; Female; Humans

2023
Phase II study of apatinib plus exemestane in estrogen receptor-positive, human epidermal growth factor receptor 2-negative metastatic breast cancer.
    Cancer biology & therapy, 2023, 12-31, Volume: 24, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Humans; Receptors, Estrogen; Vascular Endothelial Growth Factor A

2023
Palbociclib plus exemestane with gonadotropin-releasing hormone agonist versus capecitabine in premenopausal women with hormone receptor-positive, HER2-negative metastatic breast cancer (KCSG-BR15-10): a multicentre, open-label, randomised, phase 2 trial.
    The Lancet. Oncology, 2019, Volume: 20, Issue:12

    Topics: Adult; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Drug Therapy, Combination; Female; Follow-Up Studies; Gonadotropin-Releasing Hormone; Humans; Middle Aged; Neoplasm Metastasis; Piperazines; Prognosis; Pyridines; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Survival Rate

2019
Changes in serum estrogenic activity during neoadjuvant therapy with letrozole and exemestane.
    The Journal of steroid biochemistry and molecular biology, 2020, Volume: 200

    Topics: Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Cross-Over Studies; Estradiol; Estrogens; Female; Humans; Letrozole; MCF-7 Cells; Middle Aged; Neoadjuvant Therapy; Postmenopause

2020
Everolimus plus exemestane in hormone-receptor-positive, HER2-negative locally advanced or metastatic breast cancer: incidence and time course of adverse events in the phase IIIb BALLET population.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2020, Volume: 22, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Disease Progression; Everolimus; Female; Humans; Incidence; Middle Aged; Receptor, ErbB-2; Receptors, Estrogen

2020
Final results from IMPROVE: a randomized, controlled, open-label, two-arm, cross-over phase IV study to determine patients' preference for everolimus in combination with exemestane or capecitabine in combination with bevacizumab in advanced HR-positive, H
    BMC cancer, 2020, Apr-06, Volume: 20, Issue:1

    Topics: Aged; Aged, 80 and over; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Breast Neoplasms; Capecitabine; Cross-Over Studies; Estrogen Receptor alpha; Everolimus; Female; Humans; Middle Aged; Patient Preference; Prognosis; Quality of Life; Receptor, ErbB-2; Receptors, Progesterone; Survival Rate; Treatment Outcome

2020
PI3K pathway protein analyses in metastatic breast cancer patients receiving standard everolimus and exemestane.
    Journal of cancer research and clinical oncology, 2020, Volume: 146, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Drug Resistance, Neoplasm; Everolimus; Female; Humans; Middle Aged; Phosphatidylinositol 3-Kinases; Progression-Free Survival; Signal Transduction

2020
Pyrotinib with trastuzumab and aromatase inhibitors as first-line treatment for HER2 positive and hormone receptor positive metastatic or locally advanced breast cancer: study protocol of a randomized controlled trial.
    BMC cancer, 2020, Jul-13, Volume: 20, Issue:1

    Topics: Acrylamides; Adolescent; Adult; Aged; Aged, 80 and over; Aminoquinolines; Anastrozole; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Follow-Up Studies; Humans; Letrozole; Middle Aged; Prognosis; Prospective Studies; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Trastuzumab; Young Adult

2020
A Randomized Placebo Controlled Phase II Trial Evaluating Exemestane with or without Enzalutamide in Patients with Hormone Receptor-Positive Breast Cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2020, 12-01, Volume: 26, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Breast Neoplasms; Double-Blind Method; Female; Follow-Up Studies; Humans; Middle Aged; Nitriles; Phenylthiohydantoin; Prognosis; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Survival Rate

2020
Secondary endpoints analysis in patients with estrogen receptor-positive metastatic breast cancer treated with everolimus and exemestane enrolled in Oral Care-BC.
    BMC cancer, 2021, Jan-07, Volume: 21, Issue:1

    Topics: Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Case-Control Studies; Everolimus; Female; Follow-Up Studies; Humans; Japan; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Oral Health; Prognosis; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Stomatitis; Survival Rate

2021
A phase Ib/II study of xentuzumab, an IGF-neutralising antibody, combined with exemestane and everolimus in hormone receptor-positive, HER2-negative locally advanced/metastatic breast cancer.
    Breast cancer research : BCR, 2021, 01-15, Volume: 23, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Disease Management; Everolimus; Female; Humans; Maximum Tolerated Dose; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Prognosis; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Treatment Outcome

2021
The variant T allele of PvuII in ESR1 gene is a prognostic marker in early breast cancer survival.
    Scientific reports, 2021, 02-05, Volume: 11, Issue:1

    Topics: Adult; Alleles; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Disease-Free Survival; Estrogen Receptor alpha; Female; Humans; Middle Aged; Polymorphism, Single Nucleotide; Prognosis

2021
Mutation analysis using cell-free DNA for endocrine therapy in patients with HR+ metastatic breast cancer.
    Scientific reports, 2021, 03-10, Volume: 11, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Circulating Tumor DNA; DNA Mutational Analysis; Everolimus; Female; Humans; Letrozole; Middle Aged; Mutation; Neoplasm Proteins; Piperazines; Pyridines

2021
Interaction Between SNP Genotype and Efficacy of Anastrozole and Exemestane in Early-Stage Breast Cancer.
    Clinical pharmacology and therapeutics, 2021, Volume: 110, Issue:4

    Topics: Anastrozole; Androstadienes; Antigens, CD; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Epithelial-Mesenchymal Transition; Female; Humans; Lectins, C-Type; Minor Histocompatibility Antigens; Neoplasm Staging; Patient Selection; Pharmacogenomic Variants; Polymorphism, Single Nucleotide; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Treatment Outcome

2021
Alternative dosing of exemestane in postmenopausal women with ER-positive breast cancer. Design and methods of a randomized presurgical trial.
    Contemporary clinical trials, 2021, Volume: 107

    Topics: Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Postmenopause

2021
E2112: Randomized Phase III Trial of Endocrine Therapy Plus Entinostat or Placebo in Hormone Receptor-Positive Advanced Breast Cancer. A Trial of the ECOG-ACRIN Cancer Research Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2021, 10-01, Volume: 39, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Benzamides; Biomarkers, Tumor; Breast Neoplasms; Breast Neoplasms, Male; Double-Blind Method; Drug Administration Schedule; Female; Histone Deacetylase Inhibitors; Humans; Male; Middle Aged; Progression-Free Survival; Pyridines; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; South Africa; Time Factors; United States

2021
Health-related quality of life with palbociclib plus endocrine therapy versus capecitabine in postmenopausal patients with hormone receptor-positive metastatic breast cancer: Patient-reported outcomes in the PEARL study.
    European journal of cancer (Oxford, England : 1990), 2021, Volume: 156

    Topics: Androstadienes; Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Capecitabine; Disease Progression; Estrogen Receptor Antagonists; Europe; Female; Fulvestrant; Health Status; Humans; Israel; Neoplasm Metastasis; Patient Reported Outcome Measures; Piperazines; Postmenopause; Progression-Free Survival; Protein Kinase Inhibitors; Pyridines; Quality of Life; Time Factors

2021
Prevention of everolimus-related stomatitis in women with hormone receptor-positive, HER2-negative metastatic breast cancer using dexamethasone mouthwash (SWISH): a single-arm, phase 2 trial.
    The Lancet. Oncology, 2017, Volume: 18, Issue:5

    Topics: Administration, Topical; Aged; Androstadienes; Anti-Inflammatory Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Dexamethasone; Drug Eruptions; Dyspnea; Everolimus; Female; Humans; Hyperglycemia; Middle Aged; Mouthwashes; Neoplasm Metastasis; Pneumonia; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Severity of Illness Index; Stomatitis

2017
A phase II study of combined ridaforolimus and dalotuzumab compared with exemestane in patients with estrogen receptor-positive breast cancer.
    Breast cancer research and treatment, 2017, Volume: 163, Issue:3

    Topics: Adult; Aged; Androstadienes; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Disease-Free Survival; Female; Humans; Middle Aged; Protein Kinase Inhibitors; Receptors, Estrogen; Sirolimus; Stomatitis

2017
Everolimus Plus Exemestane in Advanced Breast Cancer: Safety Results of the BALLET Study on Patients Previously Treated Without and with Chemotherapy in the Metastatic Setting.
    The oncologist, 2017, Volume: 22, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Drug-Related Side Effects and Adverse Reactions; Everolimus; Female; Humans; Italy; Middle Aged; Neoplasm Metastasis

2017
Prospective assessment of patient-reported outcomes and estradiol and drug concentrations in patients experiencing toxicity from adjuvant aromatase inhibitors.
    Breast cancer research and treatment, 2017, Volume: 164, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Cross-Over Studies; Estradiol; Female; Humans; Letrozole; Middle Aged; Nitriles; Patient Reported Outcome Measures; Prospective Studies; Random Allocation; Treatment Outcome; Triazoles

2017
Osteoporosis therapy and outcomes for postmenopausal patients with hormone receptor-positive breast cancer: NCIC CTG MA.27.
    Cancer, 2017, Jul-01, Volume: 123, Issue:13

    Topics: Aged; Anastrozole; Androstadienes; Aromatase Inhibitors; Bone Density Conservation Agents; Breast Neoplasms; Chemotherapy, Adjuvant; Diphosphonates; Disease-Free Survival; Female; Humans; Male; Mastectomy; Middle Aged; Multivariate Analysis; Nitriles; Osteoporosis, Postmenopausal; Proportional Hazards Models; Radiotherapy, Adjuvant; Receptors, Estrogen; Treatment Outcome; Triazoles

2017
Long-Term Follow-Up of the Intergroup Exemestane Study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, Aug-01, Volume: 35, Issue:22

    Topics: Aged; Androstadienes; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Breast Neoplasms; Disease-Free Survival; Female; Follow-Up Studies; Humans; Middle Aged; Neoplasm Metastasis; Postmenopause; Receptors, Estrogen; Survival Rate; Tamoxifen; Time Factors

2017
A randomized phase II trial of ridaforolimus, dalotuzumab, and exemestane compared with ridaforolimus and exemestane in patients with advanced breast cancer.
    Breast cancer research and treatment, 2017, Volume: 165, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Female; Humans; Middle Aged; Neoplasm Staging; Retreatment; Sirolimus; Treatment Outcome

2017
Adjuvant tamoxifen and exemestane in women with postmenopausal early breast cancer (TEAM): 10-year follow-up of a multicentre, open-label, randomised, phase 3 trial.
    The Lancet. Oncology, 2017, Volume: 18, Issue:9

    Topics: Adenocarcinoma; Aged; Androstadienes; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Mastectomy; Middle Aged; Postmenopause; Tamoxifen; Time Factors; Treatment Outcome

2017
Fasting glucose and body mass index as predictors of activity in breast cancer patients treated with everolimus-exemestane: The EverExt study.
    Scientific reports, 2017, 09-06, Volume: 7, Issue:1

    Topics: Aged; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Blood Glucose; Body Mass Index; Breast Neoplasms; Everolimus; Fasting; Female; Humans; Kaplan-Meier Estimate; Middle Aged; Prognosis; Treatment Outcome

2017
Safety of everolimus plus exemestane in patients with hormone-receptor-positive, HER2-negative locally advanced or metastatic breast cancer: results of phase IIIb BALLET trial in Spain.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2018, Volume: 20, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Everolimus; Female; Follow-Up Studies; Humans; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Prognosis; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Safety; Survival Rate

2018
Serial immunological parameters in a phase II trial of exemestane and low-dose oral cyclophosphamide in advanced hormone receptor-positive breast cancer.
    Breast cancer research and treatment, 2018, Volume: 168, Issue:1

    Topics: Administration, Oral; Adult; Aged; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast; Breast Neoplasms; Cyclophosphamide; Disease Progression; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Humans; Middle Aged; Postmenopause; Progression-Free Survival; Receptors, Estrogen; Receptors, Progesterone; T-Lymphocytes, Regulatory

2018
Vitamin D Levels, Vitamin D Receptor Polymorphisms, and Inflammatory Cytokines in Aromatase Inhibitor-Induced Arthralgias: An Analysis of CCTG MA.27.
    Clinical breast cancer, 2018, Volume: 18, Issue:1

    Topics: Aged; Aged, 80 and over; Anastrozole; Androstadienes; Aromatase Inhibitors; Arthralgia; Breast Neoplasms; Case-Control Studies; Chemotherapy, Adjuvant; Female; Genetic Predisposition to Disease; Humans; Interleukin-1beta; Mastectomy; Middle Aged; Polymorphism, Single Nucleotide; Receptors, Calcitriol; Vitamin D

2018
Evaluation of applying IHC4 as a prognostic model in the translational study of Intergroup Exemestane Study (IES): PathIES.
    Breast cancer research and treatment, 2018, Volume: 168, Issue:1

    Topics: Aged; Androstadienes; Antineoplastic Agents, Hormonal; Breast; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Double-Blind Method; Drug Resistance, Neoplasm; Female; Humans; Immunohistochemistry; Mastectomy; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Time Factors

2018
Outcomes in women with invasive ductal or invasive lobular early stage breast cancer treated with anastrozole or exemestane in CCTG (NCIC CTG) MA.27.
    European journal of cancer (Oxford, England : 1990), 2018, Volume: 90

    Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Disease-Free Survival; Female; Humans; Middle Aged; Nitriles; Treatment Outcome; Triazoles

2018
Adjuvant anastrozole versus exemestane versus letrozole, upfront or after 2 years of tamoxifen, in endocrine-sensitive breast cancer (FATA-GIM3): a randomised, phase 3 trial.
    The Lancet. Oncology, 2018, Volume: 19, Issue:4

    Topics: Aged; Anastrozole; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Drug Administration Schedule; Female; Humans; Letrozole; Middle Aged; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen

2018
Endocrine Treatment with 2 Years of Tamoxifen versus 2 Years of Exemestane in Postmenopausal Patients with High-Risk Early Breast Cancer and Persisting Circulating Tumor Cells - First Results of the SUCCESS C Endocrine Treatment Sub-Study.
    Oncology research and treatment, 2018, Volume: 41, Issue:3

    Topics: Androstadienes; Breast Neoplasms; Female; Humans; Neoplastic Cells, Circulating; Postmenopause; Tamoxifen

2018
Everolimus Plus Exemestane vs Everolimus or Capecitabine Monotherapy for Estrogen Receptor-Positive, HER2-Negative Advanced Breast Cancer: The BOLERO-6 Randomized Clinical Trial.
    JAMA oncology, 2018, 10-01, Volume: 4, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Everolimus; Female; Humans; Kaplan-Meier Estimate; Middle Aged; Receptor, ErbB-2; Receptors, Estrogen; Treatment Outcome

2018
Tailoring Adjuvant Endocrine Therapy for Premenopausal Breast Cancer.
    The New England journal of medicine, 2018, Jul-12, Volume: 379, Issue:2

    Topics: Adult; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Middle Aged; Neoplasm Recurrence, Local; Premenopause; Receptor, ErbB-2; Tamoxifen; Young Adult

2018
Impact of age on breast cancer mortality and competing causes of death at 10 years follow-up in the adjuvant TEAM trial.
    European journal of cancer (Oxford, England : 1990), 2018, Volume: 99

    Topics: Age Factors; Aged; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast; Breast Neoplasms; Cause of Death; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Follow-Up Studies; Humans; Mastectomy; Middle Aged; Postmenopause; Receptors, Estrogen; Receptors, Progesterone; Survival Analysis; Tamoxifen

2018
Predictive Biomarkers for Endocrine Therapy: Retrospective Study in Tamoxifen and Exemestane Adjuvant Multinational (TEAM) Trial.
    Journal of the National Cancer Institute, 2018, 06-01, Volume: 110, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents, Hormonal; Biomarkers, Pharmacological; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Humans; Immunohistochemistry; Middle Aged; Postmenopause; Prognosis; Retrospective Studies; Tamoxifen; Treatment Outcome

2018
Long-term effect of exemestane therapy on bone mineral density supported by bisphosphonates: Results of 5-year adjuvant treatment in postmenopausal women with early-stage breast cancer.
    Asia-Pacific journal of clinical oncology, 2018, Volume: 14, Issue:5

    Topics: Aged; Androstadienes; Antineoplastic Agents; Bone Density; Bone Density Conservation Agents; Breast Neoplasms; Diphosphonates; Female; Humans; Middle Aged; Osteoporosis; Postmenopause

2018
Efficacy and safety of everolimus plus exemestane in postmenopausal women with hormone receptor-positive, human epidermal growth factor receptor 2-negative locally advanced or metastatic breast cancer: Results of the single-arm, phase IIIB 4EVER trial.
    International journal of cancer, 2019, 02-15, Volume: 144, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Everolimus; Female; Humans; Kaplan-Meier Estimate; Middle Aged; Neoplasm Metastasis; Outcome Assessment, Health Care; Postmenopause; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone

2019
Efficacy and safety of the combination of metformin, everolimus and exemestane in overweight and obese postmenopausal patients with metastatic, hormone receptor-positive, HER2-negative breast cancer: a phase II study.
    Investigational new drugs, 2019, Volume: 37, Issue:2

    Topics: Adult; Aged; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Drug Therapy, Combination; Everolimus; Female; Follow-Up Studies; Humans; Hypoglycemic Agents; Metformin; Middle Aged; Obesity; Overweight; Postmenopause; Prognosis; Prospective Studies; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Survival Rate

2019
Phase 2 placebo-controlled, single-blind trial to evaluate the impact of oral ibandronate on bone mineral density in osteopenic breast cancer patients receiving adjuvant aromatase inhibitors: 5-year results of the single-centre BONADIUV trial.
    European journal of cancer (Oxford, England : 1990), 2019, Volume: 108

    Topics: Absorptiometry, Photon; Adult; Aged; Anastrozole; Androstadienes; Aromatase Inhibitors; Bone Density; Bone Density Conservation Agents; Bone Diseases, Metabolic; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Ibandronic Acid; Letrozole; Middle Aged; Single-Blind Method

2019
Everolimus plus Exemestane for Hormone Receptor-Positive Advanced Breast Cancer: A PAM50 Intrinsic Subtype Analysis of BOLERO-2.
    The oncologist, 2019, Volume: 24, Issue:7

    Topics: Aged; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Double-Blind Method; Everolimus; Female; Follow-Up Studies; Humans; International Agencies; Middle Aged; Prognosis; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Retrospective Studies; Survival Rate

2019
Prognostic impact of genetic variants of CYP19A1 and UGT2B17 in a randomized trial for endocrine-responsive postmenopausal breast cancer.
    The pharmacogenomics journal, 2020, Volume: 20, Issue:1

    Topics: Aged; Androstadienes; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aromatase; Breast Neoplasms; Celecoxib; Female; Genetic Variation; Glucuronosyltransferase; Humans; Middle Aged; Minor Histocompatibility Antigens; Polymorphism, Single Nucleotide; Postmenopause; Prognosis

2020
Tucidinostat plus exemestane for postmenopausal patients with advanced, hormone receptor-positive breast cancer (ACE): a randomised, double-blind, placebo-controlled, phase 3 trial.
    The Lancet. Oncology, 2019, Volume: 20, Issue:6

    Topics: Aminopyridines; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Bone Neoplasms; Breast Neoplasms; Double-Blind Method; Female; Follow-Up Studies; Humans; Liver Neoplasms; Lung Neoplasms; Middle Aged; Neoplasm Recurrence, Local; Postmenopause; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Salvage Therapy; Survival Rate; Treatment Outcome

2019
Prognostic role of serum thymidine kinase 1 activity in patients with hormone receptor-positive metastatic breast cancer: Analysis of the randomised phase III Evaluation of Faslodex versus Exemestane Clinical Trial (EFECT).
    European journal of cancer (Oxford, England : 1990), 2019, Volume: 114

    Topics: Aged; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Female; Fulvestrant; Humans; Neoplasm Metastasis; Prognosis; Thymidine Kinase

2019
Effects of
    Pharmacogenomics, 2019, Volume: 20, Issue:8

    Topics: Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Estrogen Receptor alpha; Estrogens; Female; Genotype; Humans; Letrozole; Liver-Specific Organic Anion Transporter 1; Middle Aged; Pharmacogenetics; Polymorphism, Genetic; Tamoxifen

2019
Efficacy of everolimus with exemestane versus exemestane alone in Asian patients with HER2-negative, hormone-receptor-positive breast cancer in BOLERO-2.
    Breast cancer (Tokyo, Japan), 2014, Volume: 21, Issue:6

    Topics: Adult; Aged; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Asian People; Breast Neoplasms; Everolimus; Female; Humans; Middle Aged; Quality of Life; Receptor, ErbB-2; Sirolimus; TOR Serine-Threonine Kinases; Treatment Outcome

2014
Ganitumab with either exemestane or fulvestrant for postmenopausal women with advanced, hormone-receptor-positive breast cancer: a randomised, controlled, double-blind, phase 2 trial.
    The Lancet. Oncology, 2013, Volume: 14, Issue:3

    Topics: Aged; Androstadienes; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Disease-Free Survival; Double-Blind Method; Estradiol; Female; Fulvestrant; Humans; Middle Aged; Neoplasm Staging; Neoplasms, Hormone-Dependent; Postmenopause; Receptor, ErbB-2

2013
Effect of everolimus on bone marker levels and progressive disease in bone in BOLERO-2.
    Journal of the National Cancer Institute, 2013, May-01, Volume: 105, Issue:9

    Topics: Aged; Alkaline Phosphatase; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Bone Density; Bone Density Conservation Agents; Bone Neoplasms; Bone Remodeling; Bone Resorption; Breast Neoplasms; Collagen Type I; Confounding Factors, Epidemiologic; Disease Progression; Disease-Free Survival; Drug Administration Schedule; Everolimus; Female; Follow-Up Studies; Fractures, Spontaneous; Humans; Middle Aged; Odds Ratio; Osteogenesis; Postmenopause; Procollagen; Proportional Hazards Models; Receptors, Estrogen; Sirolimus; TOR Serine-Threonine Kinases; Treatment Failure; Treatment Outcome

2013
Health-related quality of life of patients with advanced breast cancer treated with everolimus plus exemestane versus placebo plus exemestane in the phase 3, randomized, controlled, BOLERO-2 trial.
    Cancer, 2013, May-15, Volume: 119, Issue:10

    Topics: Adult; Aged; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Disease Progression; Double-Blind Method; Drug Administration Schedule; Everolimus; Female; Health Status; Humans; Middle Aged; Odds Ratio; Postmenopause; Proportional Hazards Models; Quality of Life; Sirolimus; Surveys and Questionnaires; Treatment Outcome

2013
Genetic associations with toxicity-related discontinuation of aromatase inhibitor therapy for breast cancer.
    Breast cancer research and treatment, 2013, Volume: 138, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Estrogen Receptor alpha; Female; Humans; Introns; Letrozole; Middle Aged; Models, Genetic; Multivariate Analysis; Nitriles; Polymorphism, Single Nucleotide; Prospective Studies; Treatment Failure; Triazoles

2013
Use of the neo-adjuvant exemestane in post-menopausal estrogen receptor-positive breast cancer: a randomized phase II trial (PTEX46) to investigate the optimal duration of preoperative endocrine therapy.
    Breast (Edinburgh, Scotland), 2013, Volume: 22, Issue:3

    Topics: Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Carcinoma; Chemotherapy, Adjuvant; Drug Administration Schedule; Female; Humans; Mastectomy, Segmental; Middle Aged; Neoadjuvant Therapy; Postmenopause; Receptors, Estrogen; Time Factors

2013
Randomized phase II, double-blind, placebo-controlled study of exemestane with or without entinostat in postmenopausal women with locally recurrent or metastatic estrogen receptor-positive breast cancer progressing on treatment with a nonsteroidal aromata
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Jun-10, Volume: 31, Issue:17

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Benzamides; Biomarkers, Tumor; Breast Neoplasms; Disease-Free Survival; Double-Blind Method; Female; Humans; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Postmenopause; Pyridines; Receptors, Estrogen

2013
Randomized controlled trial of toremifene 120 mg compared with exemestane 25 mg after prior treatment with a non-steroidal aromatase inhibitor in postmenopausal women with hormone receptor-positive metastatic breast cancer.
    BMC cancer, 2013, May-16, Volume: 13

    Topics: Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Humans; Middle Aged; Neoplasm Staging; Neoplasms, Hormone-Dependent; Prognosis; Receptors, Estrogen; Survival Rate; Toremifene

2013
A randomized, double-blind, controlled study of exemestane versus anastrozole for the first-line treatment of postmenopausal Japanese women with hormone-receptor-positive advanced breast cancer.
    Breast cancer research and treatment, 2013, Volume: 139, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Biomarkers; Bone and Bones; Breast Neoplasms; Female; Humans; Japan; Lipids; Middle Aged; Neoplasm Grading; Nitriles; Postmenopause; Treatment Outcome; Triazoles

2013
Fulvestrant plus anastrozole or placebo versus exemestane alone after progression on non-steroidal aromatase inhibitors in postmenopausal patients with hormone-receptor-positive locally advanced or metastatic breast cancer (SoFEA): a composite, multicentr
    The Lancet. Oncology, 2013, Volume: 14, Issue:10

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Disease Progression; Disease-Free Survival; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Humans; Neoplasm Metastasis; Nitriles; Postmenopause; Receptors, Estrogen; Triazoles

2013
Health-related quality of life and disease symptoms in postmenopausal women with HR(+), HER2(-) advanced breast cancer treated with everolimus plus exemestane versus exemestane monotherapy.
    Current medical research and opinion, 2013, Volume: 29, Issue:11

    Topics: Adult; Aged; Androstadienes; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Disease Progression; Disease-Free Survival; Everolimus; Female; Health Status; Humans; Immunosuppressive Agents; Middle Aged; Placebos; Quality of Life; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Sirolimus; Surveys and Questionnaires; Treatment Outcome

2013
Effect of local therapy on locoregional recurrence in postmenopausal women with breast cancer in the Tamoxifen Exemestane Adjuvant Multinational (TEAM) trial.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2013, Volume: 108, Issue:2

    Topics: Aged; Androstadienes; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; International Cooperation; Mastectomy, Segmental; Maximum Tolerated Dose; Middle Aged; Multivariate Analysis; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Neoplasm Staging; Postmenopause; Prognosis; Receptors, Estrogen; Receptors, Progesterone; Reference Values; Risk Assessment; Survival Analysis; Tamoxifen; Treatment Outcome

2013
Aromatase inhibitor-induced modulation of breast density: clinical and genetic effects.
    British journal of cancer, 2013, Oct-29, Volume: 109, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Aromatase; Aromatase Inhibitors; Breast; Breast Neoplasms; Chemotherapy, Adjuvant; Estrogens; Female; Humans; Letrozole; Mammography; Middle Aged; Nitriles; Polymorphism, Single Nucleotide; Postmenopause; Prospective Studies; Triazoles

2013
Do type 1 receptor tyrosine kinases inform treatment choice? A prospectively planned analysis of the TEAM trial.
    British journal of cancer, 2013, Oct-29, Volume: 109, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Aromatase Inhibitors; Biomarkers, Tumor; Breast Neoplasms; Disease-Free Survival; ErbB Receptors; Female; Humans; Middle Aged; Molecular Sequence Data; Prognosis; Prospective Studies; Receptors, Estrogen; Receptors, Progesterone; Selective Estrogen Receptor Modulators; Tamoxifen; Tissue Array Analysis

2013
Adjuvant treatment of premenopausal women with endocrine-responsive early breast cancer: design of the TEXT and SOFT trials.
    Breast (Edinburgh, Scotland), 2013, Volume: 22, Issue:6

    Topics: Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Ovariectomy; Ovary; Premenopause; Research Design; Statistics as Topic; Tamoxifen; Triptorelin Pamoate

2013
Evaluating the 21-gene assay Recurrence Score® as a predictor of clinical response to 24 weeks of neoadjuvant exemestane in estrogen receptor-positive breast cancer.
    International journal of clinical oncology, 2014, Volume: 19, Issue:4

    Topics: Aged; Androstadienes; Breast Neoplasms; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Humans; Ki-67 Antigen; Middle Aged; Neoplasm Proteins; Neoplasm Recurrence, Local; Neoplasm Staging; Receptor, ErbB-2; Receptors, Progesterone; Treatment Outcome

2014
Everolimus plus exemestane in postmenopausal patients with HR(+) breast cancer: BOLERO-2 final progression-free survival analysis.
    Advances in therapy, 2013, Volume: 30, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Disease-Free Survival; Double-Blind Method; Everolimus; Female; Humans; Liver Neoplasms; Lung Neoplasms; Middle Aged; Postmenopause; Receptors, Estrogen; Receptors, Progesterone; Sirolimus; Treatment Outcome

2013
Safety and efficacy of everolimus with exemestane vs. exemestane alone in elderly patients with HER2-negative, hormone receptor-positive breast cancer in BOLERO-2.
    Clinical breast cancer, 2013, Volume: 13, Issue:6

    Topics: Aged; Aged, 80 and over; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Everolimus; Female; Follow-Up Studies; Humans; International Agencies; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Safety; Sirolimus; Survival Rate

2013
Effect of prior chemotherapy regimens on the efficacy of endocrine therapy within a German cohort of the TEAM trial.
    Journal of cancer research and clinical oncology, 2014, Volume: 140, Issue:1

    Topics: Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Cohort Studies; Disease-Free Survival; Female; Humans; Middle Aged; Neoplasm Grading; Neoplasm Staging; Postmenopause; Retrospective Studies; Survival Rate; Tamoxifen

2014
Everolimus plus exemestane as first-line therapy in HR⁺, HER2⁻ advanced breast cancer in BOLERO-2.
    Breast cancer research and treatment, 2014, Volume: 143, Issue:3

    Topics: Aged; Aged, 80 and over; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Disease-Free Survival; Everolimus; Female; Humans; Kaplan-Meier Estimate; Middle Aged; Neoplasm Recurrence, Local; Neoplasms, Hormone-Dependent; Receptors, Estrogen; Receptors, Progesterone; Sirolimus

2014
Effects of adjuvant exemestane versus anastrozole on bone mineral density for women with early breast cancer (MA.27B): a companion analysis of a randomised controlled trial.
    The Lancet. Oncology, 2014, Volume: 15, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Bone Density; Bone Density Conservation Agents; Bones of Lower Extremity; Breast Neoplasms; Calcium; Canada; Chemotherapy, Adjuvant; Dietary Supplements; Diphosphonates; Female; Fractures, Bone; Humans; Lumbar Vertebrae; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Radiography; Time Factors; Treatment Outcome; Triazoles; United States; Vitamin D

2014
External validity of a trial comprised of elderly patients with hormone receptor-positive breast cancer.
    Journal of the National Cancer Institute, 2014, Volume: 106, Issue:4

    Topics: Aged; Aged, 80 and over; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Kaplan-Meier Estimate; Netherlands; Odds Ratio; Receptors, Estrogen; Receptors, Progesterone; Registries; Reproducibility of Results; Tamoxifen; Treatment Outcome

2014
Bosutinib in combination with the aromatase inhibitor exemestane: a phase II trial in postmenopausal women with previously treated locally advanced or metastatic hormone receptor-positive/HER2-negative breast cancer.
    The oncologist, 2014, Volume: 19, Issue:4

    Topics: Androstadienes; Aniline Compounds; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Disease-Free Survival; Female; Humans; Nitriles; Postmenopause; Protein Kinase Inhibitors; Quinolines; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone

2014
Quality of life in MAP.3 (Mammary Prevention 3): a randomized, placebo-controlled trial evaluating exemestane for prevention of breast cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014, May-10, Volume: 32, Issue:14

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Middle Aged; Postmenopause; Quality of Life; Surveys and Questionnaires

2014
Patient-reported symptoms and discontinuation of adjuvant aromatase inhibitor therapy.
    Cancer, 2014, Aug-15, Volume: 120, Issue:16

    Topics: Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Letrozole; Middle Aged; Nitriles; Prospective Studies; Surveys and Questionnaires; Survival Analysis; Treatment Outcome; Triazoles

2014
Physical activity and survival of postmenopausal, hormone receptor-positive breast cancer patients: results of the Tamoxifen Exemestane Adjuvant Multicenter Lifestyle study.
    Cancer, 2014, Sep-15, Volume: 120, Issue:18

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Combined Modality Therapy; Exercise; Female; Follow-Up Studies; Humans; Life Style; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Postmenopause; Prognosis; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Survival Rate; Tamoxifen

2014
COX-2 expression is predictive for early relapse and aromatase inhibitor resistance in patients with ductal carcinoma in situ of the breast, and is a target for treatment.
    British journal of cancer, 2014, Jul-08, Volume: 111, Issue:1

    Topics: Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Celecoxib; Cohort Studies; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drug Resistance, Neoplasm; Female; Humans; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Prognosis; Pyrazoles; Sulfonamides; Survival Analysis

2014
Adjuvant exemestane with ovarian suppression in premenopausal breast cancer.
    The New England journal of medicine, 2014, Jul-10, Volume: 371, Issue:2

    Topics: Adult; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Estradiol; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Mastectomy; Middle Aged; Osteoporosis; Premenopause; Quality of Life; Tamoxifen; Triptorelin Pamoate

2014
Efficacy of six month neoadjuvant endocrine therapy in postmenopausal, hormone receptor-positive breast cancer patients--a phase II trial.
    European journal of cancer (Oxford, England : 1990), 2014, Volume: 50, Issue:13

    Topics: Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Postmenopause; Receptors, Estrogen; Sentinel Lymph Node Biopsy

2014
Using quality-adjusted progression-free survival as an outcome measure to assess the benefits of cancer drugs in randomized-controlled trials: case of the BOLERO-2 trial.
    Breast cancer research and treatment, 2014, Volume: 146, Issue:3

    Topics: Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Disease-Free Survival; Everolimus; Female; Humans; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Sirolimus; Thiocarbamates; Treatment Outcome

2014
Electroacupuncture for fatigue, sleep, and psychological distress in breast cancer patients with aromatase inhibitor-related arthralgia: a randomized trial.
    Cancer, 2014, Dec-01, Volume: 120, Issue:23

    Topics: Aged; Anastrozole; Androstadienes; Anxiety; Aromatase Inhibitors; Arthralgia; Breast Neoplasms; Depression; Electroacupuncture; Fatigue; Female; Humans; Letrozole; Middle Aged; Nitriles; Quality of Life; Sleep Wake Disorders; Stress, Psychological; Treatment Outcome; Triazoles

2014
Everolimus plus exemestane for hormone-receptor-positive, human epidermal growth factor receptor-2-negative advanced breast cancer: overall survival results from BOLERO-2†.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2014, Volume: 25, Issue:12

    Topics: Androstadienes; Breast Neoplasms; Double-Blind Method; ErbB Receptors; Everolimus; Female; Humans; Placebos; Sirolimus; Survival Analysis

2014
A pilot study of estradiol followed by exemestane for reversing endocrine resistance in postmenopausal women with hormone receptor-positive metastatic breast cancer.
    The oncologist, 2014, Volume: 19, Issue:11

    Topics: Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Drug Resistance, Neoplasm; Estradiol; Estrogen Receptor Modulators; Female; Humans; Middle Aged; Pilot Projects; Postmenopause; Receptors, Estrogen; Treatment Outcome

2014
Minimal impact of adjuvant exemestane or tamoxifen treatment on mammographic breast density in postmenopausal breast cancer patients: a Dutch TEAM trial analysis.
    Acta oncologica (Stockholm, Sweden), 2015, Volume: 54, Issue:3

    Topics: Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents, Hormonal; Breast Density; Breast Neoplasms; Chemotherapy, Adjuvant; Estrogen Antagonists; Female; Humans; Mammary Glands, Human; Middle Aged; Neoplasm Recurrence, Local; Postmenopause; Radiography; Tamoxifen; Treatment Outcome

2015
Adjuvant ovarian suppression in premenopausal breast cancer.
    The New England journal of medicine, 2015, Jan-29, Volume: 372, Issue:5

    Topics: Adult; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Humans; Mastectomy; Middle Aged; Premenopause; Tamoxifen

2015
Treatment-associated musculoskeletal and vasomotor symptoms and relapse-free survival in the NCIC CTG MA.27 adjuvant breast cancer aromatase inhibitor trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Jan-20, Volume: 33, Issue:3

    Topics: Adult; Aged; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Hot Flashes; Humans; Kaplan-Meier Estimate; Middle Aged; Musculoskeletal System; Nitriles; Triazoles; Vasomotor System

2015
Does patient education work in breast cancer? Final results from the global CARIATIDE study.
    Future oncology (London, England), 2015, Volume: 11, Issue:2

    Topics: Aged; Anastrozole; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Letrozole; Middle Aged; Nitriles; Patient Compliance; Patient Education as Topic; Tamoxifen; Triazoles

2015
[Everolimus plus exemestane in postmenopausal patients with estrogen-receptor-positive advanced breast cancer - Japanese subgroup analysis of BOLERO -2].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2015, Volume: 42, Issue:1

    Topics: Adult; Aged; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Double-Blind Method; Everolimus; Female; Humans; Middle Aged; Postmenopause; Receptors, Estrogen; Sirolimus

2015
Electroretinographic and optical coherence tomography findings in breast cancer patients using aromatase inhibitors.
    Cutaneous and ocular toxicology, 2016, Volume: 35, Issue:1

    Topics: Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Electroretinography; Evoked Potentials, Visual; Female; Humans; Letrozole; Middle Aged; Nerve Fibers; Nitriles; Optic Nerve; Retina; Tomography, Optical Coherence; Triazoles; Visual Acuity

2016
The prognostic and predictive value of Tregs and tumor immune subtypes in postmenopausal, hormone receptor-positive breast cancer patients treated with adjuvant endocrine therapy: a Dutch TEAM study analysis.
    Breast cancer research and treatment, 2015, Volume: 149, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Female; Forkhead Transcription Factors; Histocompatibility Antigens Class I; HLA-E Antigens; HLA-G Antigens; Humans; Immunophenotyping; Middle Aged; Neoplasm Recurrence, Local; Postmenopause; Prognosis; Receptors, Estrogen; T-Lymphocytes, Regulatory; Tamoxifen

2015
Prognostic and predictive value of ERβ1 and ERβ2 in the Intergroup Exemestane Study (IES)-first results from PathIES†.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:9

    Topics: Aged; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Biomarkers, Tumor; Breast Neoplasms; Disease-Free Survival; Double-Blind Method; Estrogen Receptor beta; Female; Humans; Middle Aged; Prognosis; Proportional Hazards Models; Retrospective Studies; Tamoxifen; Treatment Outcome

2015
Phase II Trial of Goserelin and Exemestane Combination Therapy in Premenopausal Women With Locally Advanced or Metastatic Breast Cancer.
    Medicine, 2015, Volume: 94, Issue:26

    Topics: Adult; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Goserelin; Humans; Middle Aged; Premenopause; Treatment Outcome

2015
A phase III randomized multicenter trial evaluating cognition in post-menopausal breast cancer patients receiving adjuvant hormonotherapy.
    Breast cancer research and treatment, 2015, Volume: 152, Issue:3

    Topics: Aged; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Cognition Disorders; Female; Humans; Letrozole; Memory; Middle Aged; Nitriles; Postmenopause; Psychomotor Performance; Quality of Life; Tamoxifen; Triazoles

2015
[BREAST-CONSERVING SURGERY AFTER NEOADJUVANT THERAPY FOR BREAST CANCER].
    Voprosy onkologii, 2015, Volume: 61, Issue:3

    Topics: Adult; Aged; Anastrozole; Androstadienes; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Doxorubicin; Everolimus; Female; Humans; Mastectomy, Segmental; Middle Aged; Neoadjuvant Therapy; Nitriles; Paclitaxel; Postmenopause; Receptor, ErbB-2; Receptors, Estrogen; Sirolimus; TOR Serine-Threonine Kinases; Trastuzumab; Treatment Outcome; Triazoles

2015
Abiraterone acetate, exemestane or the combination in postmenopausal patients with estrogen receptor-positive metastatic breast cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2016, Volume: 27, Issue:1

    Topics: Abiraterone Acetate; Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Disease-Free Survival; Female; Humans; Kaplan-Meier Estimate; Lymphatic Metastasis; Middle Aged; Postmenopause; Proportional Hazards Models; Receptors, Estrogen; Treatment Outcome

2016
Validation of the IHC4 Breast Cancer Prognostic Algorithm Using Multiple Approaches on the Multinational TEAM Clinical Trial.
    Archives of pathology & laboratory medicine, 2016, Volume: 140, Issue:1

    Topics: Algorithms; Androstadienes; Antineoplastic Agents; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Fluorescent Antibody Technique; Humans; Image Interpretation, Computer-Assisted; Immunohistochemistry; Kaplan-Meier Estimate; Prognosis; Tamoxifen; Treatment Outcome

2016
Twelve-Month Estrogen Levels in Premenopausal Women With Hormone Receptor-Positive Breast Cancer Receiving Adjuvant Triptorelin Plus Exemestane or Tamoxifen in the Suppression of Ovarian Function Trial (SOFT): The SOFT-EST Substudy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016, 05-10, Volume: 34, Issue:14

    Topics: Adult; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Estradiol; Estrogens; Estrone; Female; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Ovary; Tamoxifen; Triptorelin Pamoate

2016
Exemestane Use in Postmenopausal Women at High Risk for Invasive Breast Cancer: Evaluating Biomarkers of Efficacy and Safety.
    Cancer prevention research (Philadelphia, Pa.), 2016, Volume: 9, Issue:3

    Topics: Androstadienes; Aromatase Inhibitors; Biomarkers, Tumor; Bone Density; Breast Density; Breast Neoplasms; Female; Follow-Up Studies; Humans; Immunoenzyme Techniques; Lipids; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Postmenopause; Prognosis; Quality of Life; Risk Factors

2016
A phase III trial of exemestane plus bevacizumab maintenance therapy in patients with metastatic breast cancer after first-line taxane and bevacizumab: a GINECO group study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2016, Volume: 27, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Bevacizumab; Breast Neoplasms; Disease-Free Survival; Drug-Related Side Effects and Adverse Reactions; Estrogen Receptor alpha; Female; Humans; Middle Aged; Neoplasm Metastasis; Receptor, ErbB-2

2016
A Randomized, Placebo-Controlled, Phase II, Presurgical Biomarker Trial of Celecoxib Versus Exemestane in Postmenopausal Breast Cancer Patients.
    Cancer prevention research (Philadelphia, Pa.), 2016, Volume: 9, Issue:5

    Topics: Aged; Androstadienes; Antineoplastic Agents; Biomarkers, Tumor; Breast Neoplasms; Celecoxib; Cell Proliferation; Female; Humans; Immunohistochemistry; Ki-67 Antigen; Middle Aged; Postmenopause

2016
Clinical significance of the expression of autophagy-associated marker, beclin 1, in breast cancer patients who received neoadjuvant endocrine therapy.
    BMC cancer, 2016, Mar-16, Volume: 16

    Topics: Aged; Androstadienes; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Biomarkers, Tumor; Breast Neoplasms; Cell Proliferation; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Humans; Microtubule-Associated Proteins; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Prognosis

2016
Competing risks of death in women treated with adjuvant aromatase inhibitors for early breast cancer on NCIC CTG MA.27.
    Breast cancer research and treatment, 2016, Volume: 156, Issue:2

    Topics: Aged; Aged, 80 and over; Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Cardiovascular Diseases; Cause of Death; Chemotherapy, Adjuvant; Comorbidity; Female; Humans; Middle Aged; Nitriles; Postmenopause; Survival Analysis; Treatment Outcome; Triazoles

2016
Adjuvant Tamoxifen Plus Ovarian Function Suppression Versus Tamoxifen Alone in Premenopausal Women With Early Breast Cancer: Patient-Reported Outcomes in the Suppression of Ovarian Function Trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016, 05-10, Volume: 34, Issue:14

    Topics: Adult; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Lymphatic Metastasis; Ovary; Premenopause; Quality of Life; Self Report; Tamoxifen; Triptorelin Pamoate

2016
Biomarker Associations with Efficacy of Abiraterone Acetate and Exemestane in Postmenopausal Patients with Estrogen Receptor-Positive Metastatic Breast Cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2016, Dec-15, Volume: 22, Issue:24

    Topics: Abiraterone Acetate; Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents; Biomarkers, Tumor; Breast Neoplasms; Disease-Free Survival; Female; Humans; Ki-67 Antigen; Middle Aged; Neoplastic Cells, Circulating; Postmenopause; Receptors, Androgen; Receptors, Estrogen; Steroid 17-alpha-Hydroxylase

2016
Plasma ESR1 Mutations and the Treatment of Estrogen Receptor-Positive Advanced Breast Cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016, 09-01, Volume: 34, Issue:25

    Topics: Aged; Anastrozole; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Disease-Free Survival; DNA, Neoplasm; Estradiol; Estrogen Receptor alpha; Female; Fulvestrant; Humans; Middle Aged; Nitriles; Piperazines; Prospective Studies; Pyridines; Retrospective Studies; Triazoles

2016
Safety of everolimus plus exemestane in patients with hormone-receptor-positive, HER2-negative locally advanced or metastatic breast cancer progressing on prior non-steroidal aromatase inhibitors: primary results of a phase IIIb, open-label, single-arm, e
    Annals of oncology : official journal of the European Society for Medical Oncology, 2016, Volume: 27, Issue:9

    Topics: Aged; Aged, 80 and over; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Disease-Free Survival; Drug-Related Side Effects and Adverse Reactions; ErbB Receptors; Everolimus; Female; Humans; Male; Neoplasm Metastasis; Neoplasm Recurrence, Local; Postmenopause; Receptor, ErbB-2; Receptors, Estrogen; Sirolimus

2016
Evaluation of oral care to prevent oral mucositis in estrogen receptor-positive metastatic breast cancer patients treated with everolimus (Oral Care-BC): randomized controlled phase III trial.
    Japanese journal of clinical oncology, 2016, Volume: 46, Issue:9

    Topics: Aged; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Drug Therapy, Combination; Everolimus; Female; Humans; Middle Aged; Receptors, Estrogen; Severity of Illness Index; Sodium Chloride; Stomatitis

2016
Effects of exemestane and letrozole therapy on plasma concentrations of estrogens in a randomized trial of postmenopausal women with breast cancer.
    Breast cancer research and treatment, 2017, Volume: 161, Issue:3

    Topics: Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Estrogens; Female; Humans; Letrozole; Nitriles; Postmenopause; Treatment Outcome; Triazoles

2017
Specific adverse events are associated with response to exemestane therapy in postmenopausal breast cancer patients: Results from the TEAMIIA study (BOOG2006-04).
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2017, Volume: 43, Issue:4

    Topics: Aged; Aged, 80 and over; Androstadienes; Aromatase Inhibitors; Arthralgia; Arthritis; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Disease-Free Survival; Female; Hot Flashes; Humans; Joint Diseases; Logistic Models; Magnetic Resonance Imaging; Mammography; Mastectomy; Middle Aged; Multivariate Analysis; Musculoskeletal Diseases; Myalgia; Neoadjuvant Therapy; Odds Ratio; Osteoporosis; Postmenopause; Prognosis; Receptors, Estrogen; Treatment Outcome; Ultrasonography, Mammary; Vasomotor System

2017
Ki67 Proliferation Index as a Tool for Chemotherapy Decisions During and After Neoadjuvant Aromatase Inhibitor Treatment of Breast Cancer: Results From the American College of Surgeons Oncology Group Z1031 Trial (Alliance).
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, Apr-01, Volume: 35, Issue:10

    Topics: Aged; Anastrozole; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Clinical Decision-Making; Female; Follow-Up Studies; Humans; Ki-67 Antigen; Letrozole; Middle Aged; Mitotic Index; Neoadjuvant Therapy; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasm Staging; Nitriles; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Receptors, Estrogen; Receptors, Progesterone; Survival Rate; Transcriptome; Triazoles

2017
Factors Associated With Early Discontinuation of Study Treatment in the Mammary Prevention.3 Breast Cancer Chemoprevention Trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, Feb-20, Volume: 35, Issue:6

    Topics: Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Chemoprevention; Female; Humans; Menopause; Middle Aged; Patient Compliance; Patient Dropouts; Quality of Life; Surveys and Questionnaires

2017
Correlation between PIK3CA mutations in cell-free DNA and everolimus efficacy in HR
    British journal of cancer, 2017, Mar-14, Volume: 116, Issue:6

    Topics: Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Cell-Free System; Class I Phosphatidylinositol 3-Kinases; DNA Mutational Analysis; DNA, Neoplasm; Everolimus; Female; Follow-Up Studies; Humans; Immunoenzyme Techniques; Mutation; Neoplasm Metastasis; Neoplasm Staging; Phosphatidylinositol 3-Kinases; Prognosis; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Survival Rate

2017
Celecoxib anti-aromatase neoadjuvant (CAAN) trial for locally advanced breast cancer.
    The Journal of steroid biochemistry and molecular biology, 2008, Volume: 111, Issue:1-2

    Topics: Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Celecoxib; Cholesterol; Cyclooxygenase 2 Inhibitors; Female; Humans; Lipids; Middle Aged; Neoadjuvant Therapy; Postmenopause; Pyrazoles; Sulfonamides; Treatment Outcome; Tumor Burden

2008
Lipid changes in breast cancer patients on exemestane treatment: final results of the TEAM Greek substudy.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2009, Volume: 20, Issue:1

    Topics: Adenocarcinoma; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Chemotherapy, Adjuvant; Cross-Over Studies; Female; Greece; Humans; Lipid Metabolism; Lipids; Postmenopause; Tamoxifen

2009
Pharmacokinetic profile of the fulvestrant loading dose regimen in postmenopausal women with hormone receptor-positive advanced breast cancer.
    Clinical breast cancer, 2008, Volume: 8, Issue:4

    Topics: Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Double-Blind Method; Estradiol; Female; Fulvestrant; Humans; Middle Aged; Postmenopause; Receptors, Estrogen

2008
Neuropsychological functioning in postmenopausal breast cancer patients treated with tamoxifen or exemestane after AC-chemotherapy: cross-sectional findings from the neuropsychological TEAM-side study.
    Acta oncologica (Stockholm, Sweden), 2009, Volume: 48, Issue:1

    Topics: Aged; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Anxiety; Breast Neoplasms; Chemotherapy, Adjuvant; Cognition; Cognition Disorders; Cross-Sectional Studies; Cyclophosphamide; Depression; Doxorubicin; Fatigue; Female; Humans; Middle Aged; Postmenopause; Prospective Studies; Quality of Life; Tamoxifen

2009
Phase III study comparing exemestane with tamoxifen as first-line hormonal treatment of metastatic breast cancer in postmenopausal women: the European Organisation for Research and Treatment of Cancer Breast Cancer Cooperative Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Oct-20, Volume: 26, Issue:30

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Bone Neoplasms; Breast Neoplasms; Disease-Free Survival; Drug Resistance, Neoplasm; Estrogen Antagonists; Female; Humans; Lymphatic Metastasis; Middle Aged; Postmenopause; Soft Tissue Neoplasms; Tamoxifen; Treatment Outcome

2008
Celecoxib and exemestane versus placebo and exemestane in postmenopausal metastatic breast cancer patients: a double-blind phase III GINECO study.
    Breast cancer research and treatment, 2009, Volume: 116, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Anti-Inflammatory Agents, Non-Steroidal; Aromatase Inhibitors; Breast Neoplasms; Cardiovascular Diseases; Celecoxib; Chemotherapy, Adjuvant; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Liver Neoplasms; Lung Neoplasms; Lymph Nodes; Lymphatic Metastasis; Middle Aged; Neoplasms, Hormone-Dependent; Placebos; Postmenopause; Prognosis; Pyrazoles; Soft Tissue Neoplasms; Sulfonamides; Survival Rate; Treatment Outcome

2009
Activity of fulvestrant versus exemestane in advanced breast cancer patients with or without visceral metastases: data from the EFECT trial.
    Breast cancer research and treatment, 2009, Volume: 117, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Double-Blind Method; Estradiol; Female; Fulvestrant; Humans; Kaplan-Meier Estimate; Liver Neoplasms; Lung Neoplasms; Middle Aged; Viscera

2009
The effects on lipid serum levels of a 2-year adjuvant treatment with exemestane after tamoxifen in postmenopausal women with early breast cancer.
    European journal of internal medicine, 2008, Volume: 19, Issue:8

    Topics: Aged; Androstadienes; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Biomarkers; Body Composition; Breast Neoplasms; Chemotherapy, Adjuvant; Cholesterol, HDL; Cholesterol, LDL; Cohort Studies; Estrogen Receptor Modulators; Female; Humans; Lipids; Middle Aged; Postmenopause; Single-Blind Method; Tamoxifen; Treatment Outcome; Triglycerides

2008
The effect of tamoxifen or exemestane on bone mineral density during the first 2 years of adjuvant treatment of postmenopausal women with early breast cancer.
    Clinical breast cancer, 2008, Volume: 8, Issue:6

    Topics: Absorptiometry, Photon; Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Bone Density; Breast Neoplasms; Chemotherapy, Adjuvant; Double-Blind Method; Female; Humans; Middle Aged; Osteoporosis; Postmenopause; Tamoxifen

2008
Neo-adjuvant exemestane in elderly patients with breast cancer: a phase II, multicentre, open-label, Italian study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2009, Volume: 20, Issue:4

    Topics: Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Female; Humans; Treatment Outcome

2009
Exemestane as primary treatment of oestrogen receptor-positive breast cancer in postmenopausal women: a phase II trial.
    British journal of cancer, 2009, Feb-10, Volume: 100, Issue:3

    Topics: Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Combined Modality Therapy; Disease Progression; Female; Humans; Middle Aged; Postmenopause; Receptors, Estrogen; Survival Analysis

2009
Effects of exemestane and tamoxifen on bone health within the Tamoxifen Exemestane Adjuvant Multicentre (TEAM) trial: results of a German, 12-month, prospective, randomised substudy.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2009, Volume: 20, Issue:7

    Topics: Aged; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Bone Density; Bone Density Conservation Agents; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Middle Aged; Postmenopause; Prospective Studies; Tamoxifen; Treatment Outcome

2009
A comparative study of exemestane versus anastrozole in patients with postmenopausal breast cancer with visceral metastases.
    Clinical breast cancer, 2009, Volume: 9, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Androstadienes; Aromatase Inhibitors; Brain Neoplasms; Breast Neoplasms; Female; Humans; Liver Neoplasms; Lung Neoplasms; Middle Aged; Nitriles; Pilot Projects; Postmenopause; Prognosis; Retrospective Studies; Survival Rate; Treatment Outcome; Triazoles

2009
The effect of exemestane or tamoxifen on markers of bone turnover: results of a German sub-study of the Tamoxifen Exemestane Adjuvant Multicentre (TEAM) trial.
    Breast (Edinburgh, Scotland), 2009, Volume: 18, Issue:3

    Topics: Alkaline Phosphatase; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Biomarkers; Bone Density; Bone Remodeling; Bone Resorption; Breast Neoplasms; Chemotherapy, Adjuvant; Collagen Type I; Female; Follow-Up Studies; Humans; Middle Aged; Osteocalcin; Peptides; Tamoxifen; Time Factors; Treatment Outcome

2009
Extended adjuvant hormonal therapy with exemestane has no detrimental effect on the lipid profile of postmenopausal breast cancer patients: final results of the ATENA lipid substudy.
    Breast cancer research : BCR, 2009, Volume: 11, Issue:3

    Topics: Adult; Aged; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Cholesterol; Enzyme Inhibitors; Female; Humans; Lipids; Middle Aged; Postmenopause; Steroids; Tamoxifen

2009
Long-term endometrial effects in postmenopausal women with early breast cancer participating in the Intergroup Exemestane Study (IES)--a randomised controlled trial of exemestane versus continued tamoxifen after 2-3 years tamoxifen.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21, Issue:3

    Topics: Aged; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Double-Blind Method; Endometrial Neoplasms; Female; Follow-Up Studies; Humans; International Agencies; Middle Aged; Postmenopause; Survival Rate; Tamoxifen; Time Factors; Treatment Outcome; Ultrasonography

2010
A randomized trial exploring the biomarker effects of neoadjuvant sequential treatment with exemestane and anastrozole in post-menopausal women with hormone receptor-positive breast cancer.
    Breast cancer research and treatment, 2010, Volume: 119, Issue:1

    Topics: Aged; Aged, 80 and over; Anastrozole; Androstadienes; Aromatase Inhibitors; Biomarkers; Breast Neoplasms; Cell Proliferation; Chemotherapy, Adjuvant; Drug Administration Schedule; Estradiol; Female; Humans; Ki-67 Antigen; Middle Aged; Nitriles; Postmenopause; Treatment Outcome; Triazoles

2010
Widespread estrogen-dependent repression of micrornas involved in breast tumor cell growth.
    Cancer research, 2009, Nov-01, Volume: 69, Issue:21

    Topics: Androstadienes; Antineoplastic Agents; Biomarkers, Tumor; Blotting, Northern; Blotting, Western; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cell Proliferation; Estrogen Antagonists; Estrogens; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Middle Aged; Neoadjuvant Therapy; Neoplasm Invasiveness; Pilot Projects; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tamoxifen; Treatment Outcome

2009
Patterns of care in Dutch postmenopausal patients with hormone-sensitive early breast cancer participating in the Tamoxifen Exemestane Adjuvant Multinational (TEAM) trial.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21, Issue:5

    Topics: Aged; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Female; Humans; International Agencies; Middle Aged; Neoplasms, Hormone-Dependent; Postmenopause; Practice Guidelines as Topic; Practice Patterns, Physicians'; Receptors, Estrogen; Receptors, Progesterone; Retrospective Studies; Survival Rate; Tamoxifen; Treatment Outcome

2010
Cyclooxygenase-2 inhibition does not improve the reduction in ductal carcinoma in situ proliferation with aromatase inhibitor therapy: results of the ERISAC randomized placebo-controlled trial.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2010, Mar-01, Volume: 16, Issue:5

    Topics: Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Aromatase Inhibitors; Breast Neoplasms; Carcinoma in Situ; Carcinoma, Ductal, Breast; Celecoxib; Cell Proliferation; Cyclooxygenase 2; Female; Humans; Immunohistochemistry; Ki-67 Antigen; Placebos; Pyrazoles; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Sulfonamides

2010
Tremelimumab in combination with exemestane in patients with advanced breast cancer and treatment-associated modulation of inducible costimulator expression on patient T cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2010, Jul-01, Volume: 16, Issue:13

    Topics: Aged; Aged, 80 and over; Androstadienes; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; CTLA-4 Antigen; Drug Administration Schedule; Female; Humans; Inducible T-Cell Co-Stimulator Protein; Maximum Tolerated Dose; Middle Aged; Neoplasms, Hormone-Dependent; T-Lymphocytes

2010
Exemestane and chemotherapy as first-line treatment of metastatic breast cancer: results of a phase II study.
    Clinical breast cancer, 2010, Aug-01, Volume: 10, Issue:4

    Topics: Aged; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Epirubicin; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Middle Aged; Postmenopause; Treatment Outcome

2010
Reversal of skeletal effects of endocrine treatments in the Intergroup Exemestane Study.
    Breast cancer research and treatment, 2010, Volume: 124, Issue:1

    Topics: Absorptiometry, Photon; Aged; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Australia; Biomarkers; Bone Density; Breast Neoplasms; Chemotherapy, Adjuvant; Double-Blind Method; Estrogen Antagonists; Europe; Female; Fractures, Bone; Humans; Middle Aged; Odds Ratio; Risk Assessment; Risk Factors; Tamoxifen; Time Factors; United States

2010
Endometrial effects of exemestane compared to tamoxifen within the Tamoxifen Exemestane Adjuvant Multicenter (TEAM) trial: results of a prospective gynecological ultrasound substudy.
    Gynecologic oncology, 2010, Volume: 119, Issue:3

    Topics: Androstadienes; Antineoplastic Agents; Breast Neoplasms; Chemotherapy, Adjuvant; Endometrium; Female; Humans; Middle Aged; Postmenopause; Prospective Studies; Receptors, Estrogen; Receptors, Progesterone; Selective Estrogen Receptor Modulators; Tamoxifen; Ultrasonography; Uterine Diseases

2010
Genome-wide case-control study of musculoskeletal adverse events and functional genomics in women receiving aromatase inhibitors: going beyond associations.
    Breast cancer research : BCR, 2010, Dec-20, Volume: 12 Suppl 4

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Case-Control Studies; Female; Gene Expression; Genome-Wide Association Study; Humans; Interleukin-17; Linkage Disequilibrium; Musculoskeletal Diseases; Nitriles; Pharmacogenetics; Polymorphism, Single Nucleotide; Triazoles

2010
A randomized, placebo-controlled trial (NCIC CTG MAP.2) examining the effects of exemestane on mammographic breast density, bone density, markers of bone metabolism and serum lipid levels in postmenopausal women.
    Breast cancer research and treatment, 2011, Volume: 126, Issue:2

    Topics: Alkaline Phosphatase; Androstadienes; Aromatase Inhibitors; Bone and Bones; Bone Density; Breast; Breast Neoplasms; Collagen Type I; Double-Blind Method; Female; Humans; Lipid Metabolism; Lipids; Mammography; Middle Aged; Peptides; Postmenopause

2011
Bone metabolism and quality-of-life of postmenopausal women with invasive breast cancer receiving neoadjuvant hormonal therapy: sub-analyses from celecoxib anti-aromatase neoadjuvant (CAAN) trial.
    The Journal of steroid biochemistry and molecular biology, 2011, Volume: 125, Issue:1-2

    Topics: Androstadienes; Animals; Antineoplastic Agents; Aromatase Inhibitors; Biomarkers; Bone and Bones; Bone Density; Breast Neoplasms; Celecoxib; Cyclooxygenase 2 Inhibitors; Drug Therapy, Combination; Female; Humans; Neoadjuvant Therapy; Postmenopause; Pyrazoles; Quality of Life; Sulfonamides; Surveys and Questionnaires; Treatment Outcome

2011
Adjuvant tamoxifen and exemestane in early breast cancer (TEAM): a randomised phase 3 trial.
    Lancet (London, England), 2011, Jan-22, Volume: 377, Issue:9762

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents, Hormonal; Breast Neoplasms; Disease-Free Survival; Early Diagnosis; Female; Humans; Middle Aged; Postmenopause; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen

2011
The effect of exemestane, anastrozole, and tamoxifen on lipid profiles in Japanese postmenopausal early breast cancer patients: final results of National Surgical Adjuvant Study BC 04, the TEAM Japan sub-study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2011, Volume: 22, Issue:8

    Topics: Aged; Aged, 80 and over; Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Female; Humans; Japan; Lipids; Middle Aged; Neoplasm Staging; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Tamoxifen; Triazoles; Triglycerides

2011
Estrogen receptor and progesterone receptor as predictive biomarkers of response to endocrine therapy: a prospectively powered pathology study in the Tamoxifen and Exemestane Adjuvant Multinational trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Apr-20, Volume: 29, Issue:12

    Topics: Androstadienes; Aromatase Inhibitors; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Europe; Female; Humans; Immunohistochemistry; Middle Aged; Patient Selection; Predictive Value of Tests; Proportional Hazards Models; Prospective Studies; Receptors, Estrogen; Receptors, Progesterone; Recurrence; Risk Assessment; Risk Factors; Selective Estrogen Receptor Modulators; Survival Analysis; Tamoxifen; Time Factors; Tissue Array Analysis; Treatment Outcome

2011
Effects of exemestane, anastrozole and tamoxifen on bone mineral density and bone turnover markers in postmenopausal early breast cancer patients: results of N-SAS BC 04, the TEAM Japan substudy.
    Oncology, 2010, Volume: 79, Issue:5-6

    Topics: Aged; Aged, 80 and over; Anastrozole; Androstadienes; Antineoplastic Agents; Bone and Bones; Bone Density; Bone Resorption; Breast Neoplasms; Female; Humans; Middle Aged; Nitriles; Postmenopause; Tamoxifen; Triazoles

2010
Randomized phase II neoadjuvant comparison between letrozole, anastrozole, and exemestane for postmenopausal women with estrogen receptor-rich stage 2 to 3 breast cancer: clinical and biomarker outcomes and predictive value of the baseline PAM50-based int
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Jun-10, Volume: 29, Issue:17

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Biomarkers, Tumor; Breast Neoplasms; Female; Humans; Ki-67 Antigen; Letrozole; Neoadjuvant Therapy; Neoplasm Staging; Nitriles; Postmenopause; Prognosis; Receptors, Estrogen; Triazoles

2011
Exemestane for breast-cancer prevention in postmenopausal women.
    The New England journal of medicine, 2011, Jun-23, Volume: 364, Issue:25

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Double-Blind Method; Female; Follow-Up Studies; Humans; Incidence; Middle Aged; Neoplasm Invasiveness; Postmenopause; Quality of Life; Risk Factors

2011
Androgens and musculoskeletal symptoms among breast cancer patients on aromatase inhibitor therapy.
    Breast cancer research and treatment, 2011, Volume: 130, Issue:2

    Topics: Aged; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Dehydroepiandrosterone Sulfate; Female; Humans; Letrozole; Middle Aged; Musculoskeletal Pain; Nitriles; Testosterone; Triazoles

2011
Exemestane versus anastrozole as front-line endocrine therapy in postmenopausal patients with hormone receptor-positive, advanced breast cancer: final results from the Spanish Breast Cancer Group 2001-03 phase 2 randomized trial.
    Cancer, 2012, Jan-01, Volume: 118, Issue:1

    Topics: Aged; Aged, 80 and over; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Cross-Over Studies; Disease-Free Survival; Female; Humans; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Treatment Outcome; Triazoles

2012
Phase II trial of neoadjuvant exemestane in combination with celecoxib in postmenopausal women who have breast cancer.
    Clinical breast cancer, 2011, Volume: 11, Issue:4

    Topics: Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Lobular; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Immunoenzyme Techniques; Lymphatic Metastasis; Middle Aged; Neoadjuvant Therapy; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Neoplasm Staging; Postmenopause; Pyrazoles; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Sulfonamides; Survival Rate; Treatment Outcome

2011
Pathological complete response rates following different neoadjuvant chemotherapy regimens for operable breast cancer according to ER status, in two parallel, randomized phase II trials with an adaptive study design (ECTO II).
    Breast cancer research and treatment, 2012, Volume: 132, Issue:3

    Topics: Adult; Aged; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Cyclophosphamide; Deoxycytidine; Doxorubicin; Female; Fluorouracil; Humans; Leukopenia; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Invasiveness; Neoplasm, Residual; Neutropenia; Paclitaxel; Receptors, Estrogen; Treatment Outcome

2012
Increased 5α-reductase type 2 expression in human breast carcinoma following aromatase inhibitor therapy: the correlation with decreased tumor cell proliferation.
    Hormones & cancer, 2011, Volume: 2, Issue:1

    Topics: 17-Hydroxysteroid Dehydrogenases; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Carcinoma, Ductal, Breast; Celecoxib; Cell Proliferation; Female; Humans; Immunohistochemistry; Letrozole; Neoadjuvant Therapy; Nitriles; Pyrazoles; Receptors, Androgen; Sulfonamides; Treatment Outcome; Triazoles

2011
Plasma letrozole concentrations in postmenopausal women with breast cancer are associated with CYP2A6 genetic variants, body mass index, and age.
    Clinical pharmacology and therapeutics, 2011, Volume: 90, Issue:5

    Topics: Administration, Oral; Adult; Age Factors; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents; Aryl Hydrocarbon Hydroxylases; Body Mass Index; Breast Neoplasms; Cross-Over Studies; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP3A; Female; Genetic Variation; Genotype; Humans; Letrozole; Middle Aged; Nitriles; Pharmacogenetics; Postmenopause; Prospective Studies; Triazoles

2011
Disease-related outcomes with long-term follow-up: an updated analysis of the intergroup exemestane study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Mar-01, Volume: 30, Issue:7

    Topics: Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Follow-Up Studies; Humans; Middle Aged; Postmenopause; Treatment Outcome

2012
Everolimus in postmenopausal hormone-receptor-positive advanced breast cancer.
    The New England journal of medicine, 2012, Feb-09, Volume: 366, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Bone Neoplasms; Breast Neoplasms; Disease-Free Survival; ErbB Receptors; Everolimus; Female; Humans; Kaplan-Meier Estimate; Middle Aged; Postmenopause; Recurrence; Sirolimus; Stomatitis; TOR Serine-Threonine Kinases

2012
Using the gene ontology to scan multilevel gene sets for associations in genome wide association studies.
    Genetic epidemiology, 2012, Volume: 36, Issue:1

    Topics: Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Case-Control Studies; Data Mining; Female; Genome-Wide Association Study; Genome, Human; Humans; Linkage Disequilibrium; Models, Genetic; Nitriles; Polymorphism, Single Nucleotide; Raloxifene Hydrochloride; Software; Tamoxifen; Triazoles

2012
Comparison of changes in the lipid profile of postmenopausal women with early stage breast cancer treated with exemestane or letrozole.
    Journal of clinical pharmacology, 2012, Volume: 52, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Letrozole; Lipids; Middle Aged; Nitriles; Postmenopause; Tamoxifen; Triazoles

2012
Age-specific nonpersistence of endocrine therapy in postmenopausal patients diagnosed with hormone receptor-positive breast cancer: a TEAM study analysis.
    The oncologist, 2012, Volume: 17, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Follow-Up Studies; Humans; Middle Aged; Postmenopause; Survival Rate; Tamoxifen; Treatment Outcome

2012
Health-related quality of life, psychological distress, and adverse events in postmenopausal women with breast cancer who receive tamoxifen, exemestane, or anastrozole as adjuvant endocrine therapy: National Surgical Adjuvant Study of Breast Cancer 04 (N-
    Breast cancer research and treatment, 2012, Volume: 133, Issue:1

    Topics: Aged; Anastrozole; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Chemotherapy, Adjuvant; Depression; Female; Humans; Maintenance Chemotherapy; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Quality of Life; Stress, Psychological; Surveys and Questionnaires; Tamoxifen; Treatment Outcome; Triazoles

2012
Carpal tunnel syndrome and musculoskeletal symptoms in postmenopausal women with early breast cancer treated with exemestane or tamoxifen after 2-3 years of tamoxifen: a retrospective analysis of the Intergroup Exemestane Study.
    The Lancet. Oncology, 2012, Volume: 13, Issue:4

    Topics: Aged; Aged, 80 and over; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Carpal Tunnel Syndrome; Disease-Free Survival; Female; Humans; Middle Aged; Musculoskeletal Abnormalities; Postmenopause; Retrospective Studies; Surveys and Questionnaires; Tamoxifen; Treatment Outcome

2012
Bone density and structure in healthy postmenopausal women treated with exemestane for the primary prevention of breast cancer: a nested substudy of the MAP.3 randomised controlled trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:3

    Topics: Absorptiometry, Photon; Androstadienes; Anticarcinogenic Agents; Aromatase Inhibitors; Bone and Bones; Bone Density; Breast Neoplasms; Calcium; Canada; Chi-Square Distribution; Dietary Supplements; Double-Blind Method; Female; Femur Neck; Hip Joint; Humans; Lumbar Vertebrae; Middle Aged; Osteoporosis; Patient Selection; Placebos; Postmenopause; Primary Prevention; Risk Assessment; Risk Factors; Time Factors; Tomography, X-Ray Computed; Treatment Outcome; United States; Vitamin D

2012
Effects of exemestane and tamoxifen on hormone levels within the Tamoxifen Exemestane Adjuvant Multicentre (TEAM) trial: results of a German substudy.
    Climacteric : the journal of the International Menopause Society, 2012, Volume: 15, Issue:5

    Topics: Aged; Androstadienes; Antineoplastic Agents; Bone Density; Bone Density Conservation Agents; Breast Neoplasms; Dehydroepiandrosterone Sulfate; Female; Follicle Stimulating Hormone; Germany; Hormones; Humans; Middle Aged; Parathyroid Hormone; Postmenopause; Receptors, Estrogen; Sex Hormone-Binding Globulin; Tamoxifen; Testosterone

2012
Predictors of aromatase inhibitor discontinuation as a result of treatment-emergent symptoms in early-stage breast cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Mar-20, Volume: 30, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Comorbidity; Female; Follow-Up Studies; Humans; Letrozole; Medication Adherence; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Prognosis; Prospective Studies; Triazoles; Withholding Treatment

2012
Long-term assessment of quality of life in the Intergroup Exemestane Study: 5 years post-randomisation.
    British journal of cancer, 2012, Mar-13, Volume: 106, Issue:6

    Topics: Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials, Phase III as Topic; Drug Substitution; Female; Follow-Up Studies; Humans; Libido; Neoplasms, Unknown Primary; Postmenopause; Quality of Life; Receptors, Estrogen; Surveys and Questionnaires; Tamoxifen; Treatment Outcome; Vaginal Discharge

2012
Phase II trial of exemestane in combination with fulvestrant in postmenopausal women with advanced, hormone-responsive breast cancer.
    Clinical breast cancer, 2012, Volume: 12, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Estradiol; Female; Fulvestrant; Humans; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Middle Aged; Postmenopause; Receptors, Estrogen; Receptors, Progesterone

2012
Quality of life in relation to tamoxifen or exemestane treatment in postmenopausal breast cancer patients: a Tamoxifen Exemestane Adjuvant Multinational (TEAM) Trial side study.
    Breast cancer research and treatment, 2012, Volume: 134, Issue:1

    Topics: Aged; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Chemotherapy, Adjuvant; Female; Humans; Middle Aged; Postmenopause; Quality of Life; Surveys and Questionnaires; Tamoxifen

2012
Correlation of treatment-emergent adverse events and clinical response to endocrine therapy in early breast cancer: a retrospective analysis of the German cohort of TEAM.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2012, Volume: 23, Issue:10

    Topics: Aged; Androstadienes; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cohort Studies; Female; Germany; Humans; Middle Aged; Retrospective Studies; Tamoxifen

2012
Exemestane for breast cancer prevention: a critical shift?
    Cancer discovery, 2012, Volume: 2, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Anticarcinogenic Agents; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Middle Aged; Risk Factors

2012
The BOLERO-2 trial: the addition of everolimus to exemestane in the treatment of postmenopausal hormone receptor-positive advanced breast cancer.
    Future oncology (London, England), 2012, Volume: 8, Issue:6

    Topics: Adult; Aged; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Everolimus; Female; Humans; Middle Aged; Neoplasm Staging; Postmenopause; Receptor, ErbB-2; Receptors, Estrogen; Sirolimus; Treatment Outcome

2012
Influence of semi-quantitative oestrogen receptor expression on adjuvant endocrine therapy efficacy in ductal and lobular breast cancer - a TEAM study analysis.
    European journal of cancer (Oxford, England : 1990), 2013, Volume: 49, Issue:2

    Topics: Aged; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Chemotherapy, Adjuvant; Female; Humans; Postmenopause; Receptors, Estrogen; Tamoxifen

2013
Compliance, analgesic use and side-effect protection within a German cohort of the TEAM trial.
    Anticancer research, 2012, Volume: 32, Issue:9

    Topics: Analgesics; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Disease-Free Survival; Drug Interactions; Female; Fractures, Bone; Humans; Medication Adherence; Middle Aged; Retrospective Studies; Tamoxifen

2012
Mammostrat as an immunohistochemical multigene assay for prediction of early relapse risk in the tamoxifen versus exemestane adjuvant multicenter trial pathology study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Dec-20, Volume: 30, Issue:36

    Topics: Androstadienes; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Humans; Immunohistochemistry; Neoplasms, Hormone-Dependent; Recurrence; Retrospective Studies; Risk Factors; Tamoxifen; Tissue Array Analysis

2012
Phase I trial of exemestane in combination with metformin and rosiglitazone in nondiabetic obese postmenopausal women with hormone receptor-positive metastatic breast cancer.
    Cancer chemotherapy and pharmacology, 2013, Volume: 71, Issue:1

    Topics: Administration, Oral; Aged; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Metformin; Middle Aged; Obesity; Overweight; Postmenopause; Rosiglitazone; Thiazolidinediones; Time Factors

2013
Elderly postmenopausal patients with breast cancer are at increased risk for distant recurrence: a tamoxifen exemestane adjuvant multinational study analysis.
    The oncologist, 2013, Volume: 18, Issue:1

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Female; Humans; Middle Aged; Neoplasm Staging; Neoplasms, Hormone-Dependent; Postmenopause; Recurrence; Tamoxifen; Treatment Outcome

2013
Exemestane versus anastrozole in postmenopausal women with early breast cancer: NCIC CTG MA.27--a randomized controlled phase III trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Apr-10, Volume: 31, Issue:11

    Topics: Aged; Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Disease-Free Survival; Female; Follow-Up Studies; History, 18th Century; Hot Flashes; Humans; Hypercholesterolemia; Kaplan-Meier Estimate; Middle Aged; Nitriles; Osteoporosis; Postmenopause; Time Factors; Treatment Outcome; Triazoles

2013
[Phase I single-dose administration study of exemestane in postmenopausal women].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:7

    Topics: Androstadienes; Antineoplastic Agents; Breast Neoplasms; Cross-Over Studies; Estrogens; Fasting; Female; Humans; Middle Aged; Postmenopause

2002
[Late phase II study of exemestane in postmenopausal patients with breast cancer resistant to anti-estrogenic agents].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Drug Administration Schedule; Drug Resistance, Neoplasm; Enzyme Inhibitors; Estrogen Antagonists; Estrogens; Female; Hot Flashes; Humans; Hypertension; Middle Aged; Postmenopause; Reproducibility of Results

2002
[Early phase II dose-finding study of exemestane in postmenopausal patients with advanced/recurrent breast cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:7

    Topics: Administration, Oral; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Drug Administration Schedule; Estrogens; Female; Headache; Hot Flashes; Humans; Middle Aged; Nausea; Postmenopause; Receptors, Estrogen

2002
[Treatment of advanced metastatic breast cancer with exemestane, a multicenter randomized controlled study of 195 cases].
    Zhonghua yi xue za zhi, 2003, Feb-10, Volume: 83, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Double-Blind Method; Female; Humans; Middle Aged

2003
Mature results of a randomized phase II multicenter study of exemestane versus tamoxifen as first-line hormone therapy for postmenopausal women with metastatic breast cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2003, Volume: 14, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents, Hormonal; Breast Neoplasms; Female; Humans; Middle Aged; Postmenopause; Tamoxifen; Treatment Outcome

2003
Celecoxib anti-aromatase neoadjuvant (CAAN) trial for locally advanced breast cancer: preliminary report.
    The Journal of steroid biochemistry and molecular biology, 2003, Volume: 86, Issue:3-5

    Topics: Androstadienes; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Carcinoembryonic Antigen; Celecoxib; Enzyme Inhibitors; Female; Humans; Letrozole; Middle Aged; Neoadjuvant Therapy; Nitriles; Postmenopause; Pyrazoles; Sulfonamides; Treatment Outcome; Triazoles

2003
The effect of exemestane on serum lipid profile in postmenopausal women with metastatic breast cancer: a companion study to EORTC Trial 10951, 'Randomized phase II study in first line hormonal treatment for metastatic breast cancer with exemestane or tamo
    Annals of oncology : official journal of the European Society for Medical Oncology, 2004, Volume: 15, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Arteriosclerosis; Breast Neoplasms; Cholesterol; Enzyme Inhibitors; Female; Humans; Lipids; Middle Aged; Neoplasm Metastasis; Postmenopause; Risk Factors; Tamoxifen

2004
A randomized trial of exemestane after two to three years of tamoxifen therapy in postmenopausal women with primary breast cancer.
    The New England journal of medicine, 2004, Mar-11, Volume: 350, Issue:11

    Topics: Administration, Oral; Aged; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Double-Blind Method; Estrogen Antagonists; Female; Humans; Middle Aged; Neoplasms, Hormone-Dependent; Postmenopause; Receptors, Estrogen; Tamoxifen

2004
Pilot study evaluating the pharmacokinetics, pharmacodynamics, and safety of the combination of exemestane and tamoxifen.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Mar-15, Volume: 10, Issue:6

    Topics: Administration, Oral; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Estradiol; Estrone; Female; History, 18th Century; Humans; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Pilot Projects; Tamoxifen

2004
Her2/neu expression predicts the response to antiaromatase neoadjuvant therapy in primary breast cancer: subgroup analysis from celecoxib antiaromatase neoadjuvant trial.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Jul-15, Volume: 10, Issue:14

    Topics: Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Celecoxib; Cyclooxygenase Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; In Situ Hybridization, Fluorescence; Letrozole; Middle Aged; Neoadjuvant Therapy; Nitriles; Prognosis; Pyrazoles; Receptor, ErbB-2; Sulfonamides; Treatment Outcome; Triazoles

2004
The role of aromatase inhibitors in the adjuvant treatment of breast carcinoma: the M. D. Anderson Cancer Center evidence-based approach.
    Cancer, 2004, Oct-01, Volume: 101, Issue:7

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Double-Blind Method; Enzyme Inhibitors; Evidence-Based Medicine; Female; Humans; Letrozole; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Prospective Studies; Tamoxifen; Triazoles

2004
Endocrine effects of tamoxifen plus exemestane in postmenopausal women with breast cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Feb-15, Volume: 11, Issue:4

    Topics: Adult; Aged; Alkaline Phosphatase; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Cholesterol, HDL; Estradiol; Estrogen Antagonists; Estrone; Exanthema; Female; Hot Flashes; Humans; Middle Aged; Postmenopause; Tamoxifen; Treatment Outcome

2005
Phase II study of sequential hormonal therapy with anastrozole/exemestane in advanced and metastatic breast cancer.
    British journal of cancer, 2005, May-09, Volume: 92, Issue:9

    Topics: Administration, Oral; Adult; Aged; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Triazoles

2005
Effects of exemestane administered for 2 years versus placebo on bone mineral density, bone biomarkers, and plasma lipids in patients with surgically resected early breast cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Aug-01, Volume: 23, Issue:22

    Topics: Aged; Androstadienes; Aromatase Inhibitors; Bone Density; Bone Resorption; Breast Neoplasms; Double-Blind Method; Female; Humans; Lipids; Middle Aged; Placebos; Postmenopause

2005
Effect of exemestane on the lipidemic profile of post-menopausal operable breast cancer patients following 5-7 years of adjuvant tamoxifen: preliminary results of the ATENA substudy.
    Anti-cancer drugs, 2005, Volume: 16, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Chemotherapy, Adjuvant; Cholesterol; Enzyme Inhibitors; Female; Humans; Lipids; Middle Aged; Postmenopause; Risk Factors

2005
The effect of exemestane on the lipidemic profile of postmenopausal early breast cancer patients: preliminary results of the TEAM Greek sub-study.
    Breast cancer research and treatment, 2005, Volume: 93, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Female; Greece; Humans; Lipids; Middle Aged; Postmenopause; Selective Estrogen Receptor Modulators; Tamoxifen; Treatment Outcome; Triglycerides

2005
Effect of exemestane on tamoxifen pharmacokinetics in postmenopausal women treated for breast cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Dec-15, Volume: 11, Issue:24 Pt 1

    Topics: Adult; Aged; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Drug Interactions; Estradiol; Estrone; Female; Humans; Middle Aged; Postmenopause; Tamoxifen

2005
Serum lipid profiles in patients receiving endocrine treatment for breast cancer--the results from the Celecoxib Anti-Aromatase Neoadjuvant (CAAN) Trial.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2005, Volume: 59 Suppl 2

    Topics: Aged; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Celecoxib; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cyclooxygenase 2 Inhibitors; Enzyme Inhibitors; Female; Humans; Lipids; Middle Aged; Pyrazoles; Sulfonamides; Triglycerides

2005
Exemestane as adjuvant treatment of early breast cancer: intergroup exemestane study/tamoxifen exemestane adjuvant multicenter trials.
    Clinical breast cancer, 2006, Volume: 6 Suppl 2

    Topics: Aged; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Cross-Over Studies; Disease-Free Survival; Female; Humans; Middle Aged; Postmenopause; Tamoxifen; Treatment Outcome

2006
Exemestane after tamoxifen as adjuvant hormonal therapy in postmenopausal women with breast cancer: effects on body composition and lipids.
    British journal of cancer, 2006, Jul-17, Volume: 95, Issue:2

    Topics: Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Body Composition; Breast Neoplasms; Chemotherapy, Adjuvant; Cholesterol, HDL; Cholesterol, LDL; Disease-Free Survival; Female; Humans; Lipid Metabolism; Middle Aged; Obesity; Postmenopause; Quality of Life; Tamoxifen; Treatment Outcome; Triglycerides

2006
Changes in bone turnover and in bone mass in women with breast cancer switched from tamoxifen to exemestane.
    Bone, 2007, Volume: 40, Issue:1

    Topics: Alkaline Phosphatase; Androstadienes; Aromatase Inhibitors; Biomarkers; Bone and Bones; Bone Density; Bone Remodeling; Bone Resorption; Breast Neoplasms; Collagen Type I; Female; Humans; Middle Aged; Peptides; Radiography; Tamoxifen

2007
Changes in bone and lipid metabolism in postmenopausal women with early breast cancer after terminating 2-year treatment with exemestane: a randomised, placebo-controlled study.
    European journal of cancer (Oxford, England : 1990), 2006, Volume: 42, Issue:17

    Topics: Androstadienes; Aromatase Inhibitors; Biomarkers; Blood Coagulation Factors; Bone and Bones; Bone Density; Bone Remodeling; Breast Neoplasms; Female; Follow-Up Studies; Gonadal Steroid Hormones; Homocysteine; Humans; Lipids; Middle Aged; Postmenopause; Vitamin D; Withholding Treatment

2006
A feasibility study of the efficacy and tolerability of the combination of Exemestane with the COX-2 inhibitor Celecoxib in post-menopausal patients with advanced breast cancer.
    European journal of cancer (Oxford, England : 1990), 2006, Volume: 42, Issue:16

    Topics: Adult; Aged; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Celecoxib; Cyclooxygenase 2 Inhibitors; Disease-Free Survival; Feasibility Studies; Female; Humans; Middle Aged; Postmenopause; Pyrazoles; Quality of Life; Sulfonamides; Treatment Outcome

2006
Cost-effectiveness of exemestane versus tamoxifen as adjuvant therapy for early-stage breast cancer after 2-3 years treatment with tamoxifen in Sweden.
    Breast cancer research and treatment, 2007, Volume: 102, Issue:3

    Topics: Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Cost-Benefit Analysis; Disease-Free Survival; Female; Humans; Neoplasm Recurrence, Local; Quality of Life; Sweden; Tamoxifen

2007
Skeletal effects of exemestane on bone-mineral density, bone biomarkers, and fracture incidence in postmenopausal women with early breast cancer participating in the Intergroup Exemestane Study (IES): a randomised controlled study.
    The Lancet. Oncology, 2007, Volume: 8, Issue:2

    Topics: Androstadienes; Antineoplastic Agents; Biomarkers; Bone Density; Bone Remodeling; Breast Neoplasms; Female; Follow-Up Studies; Fractures, Bone; Hip; Humans; Incidence; Lumbar Vertebrae; Postmenopause; Radiography; Risk Factors; Spine; Tamoxifen; Time Factors; Treatment Outcome

2007
Survival and safety of exemestane versus tamoxifen after 2-3 years' tamoxifen treatment (Intergroup Exemestane Study): a randomised controlled trial.
    Lancet (London, England), 2007, Feb-17, Volume: 369, Issue:9561

    Topics: Aged; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Disease-Free Survival; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Middle Aged; Neoplasm Recurrence, Local; Postmenopause; Selective Estrogen Receptor Modulators; Survival Analysis; Tamoxifen

2007
Phase 2 randomized trial of primary endocrine therapy versus chemotherapy in postmenopausal patients with estrogen receptor-positive breast cancer.
    Cancer, 2007, Jul-15, Volume: 110, Issue:2

    Topics: Aged; Aged, 80 and over; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Doxorubicin; Female; Humans; Middle Aged; Nitriles; Paclitaxel; Postmenopause; Receptors, Estrogen; Triazoles

2007
Effects of steroidal and nonsteroidal aromatase inhibitors on markers of bone turnover in healthy postmenopausal women.
    Breast cancer research : BCR, 2007, Volume: 9, Issue:4

    Topics: Aged; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Biomarkers; Bone Density; Bone Remodeling; Bone Resorption; Breast Neoplasms; Estrogens; Female; Humans; Letrozole; Lipids; Menopause; Middle Aged; Nitriles; Peptide Fragments; Placebos; Procollagen; Single-Blind Method; Tamoxifen; Triazoles

2007
Comparison of menopausal symptoms during the first year of adjuvant therapy with either exemestane or tamoxifen in early breast cancer: report of a Tamoxifen Exemestane Adjuvant Multicenter trial substudy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Oct-20, Volume: 25, Issue:30

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Double-Blind Method; Female; Follow-Up Studies; Hot Flashes; Humans; Menopause; Middle Aged; Quality of Life; Surveys and Questionnaires; Tamoxifen; Time Factors; Treatment Outcome

2007
Pharmacokinetics and tolerability of exemestane in combination with raloxifene in postmenopausal women with a history of breast cancer.
    Breast cancer research and treatment, 2008, Volume: 111, Issue:2

    Topics: Aged; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Drug Therapy, Combination; Estradiol; Estrone; Female; Humans; Middle Aged; Postmenopause; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators

2008
[Phase II clinical trial of neoadjuvant hormone therapy in comparison with chemotherapy of patients with breast cancer].
    Voprosy onkologii, 2007, Volume: 53, Issue:4

    Topics: Aged; Aged, 80 and over; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Doxorubicin; Female; Humans; Mammography; Middle Aged; Neoadjuvant Therapy; Nitriles; Paclitaxel; Postmenopause; Receptors, Estrogen; Receptors, Progesterone; Treatment Outcome; Triazoles

2007
Postoperative dose-dense sequential chemotherapy with epirubicin, paclitaxel and CMF in patients with high-risk breast cancer: safety analysis of the Hellenic Cooperative Oncology Group randomized phase III trial HE 10/00.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2008, Volume: 19, Issue:5

    Topics: Adult; Aged; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Drug; Epirubicin; Estrogens; Female; Fluorouracil; Granulocyte Colony-Stimulating Factor; Hematologic Diseases; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Neoplasms, Hormone-Dependent; Neoplasms, Second Primary; Paclitaxel; Peripheral Nervous System Diseases; Tamoxifen

2008
Multicenter phase II trial of neoadjuvant exemestane for postmenopausal patients with hormone receptor-positive, operable breast cancer: Saitama Breast Cancer Clinical Study Group (SBCCSG-03).
    Breast cancer research and treatment, 2008, Volume: 107, Issue:1

    Topics: Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Female; Humans; Mastectomy; Middle Aged; Neoadjuvant Therapy; Postmenopause; Receptors, Estrogen; Receptors, Progesterone; Time Factors; Treatment Outcome

2008
Exemestane as primary systemic treatment for hormone receptor positive post-menopausal breast cancer patients: a phase II trial of the Austrian Breast and Colorectal Cancer Study Group (ABCSG-17).
    Breast cancer research and treatment, 2008, Volume: 112, Issue:1

    Topics: Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Ductal, Breast; Female; Humans; Middle Aged; Postmenopause; Prognosis; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone

2008
National Cancer Institute of Canada Clinical Trials Group MAP.3 Trial: evaluation of exemestane to prevent breast cancer in postmenopausal women.
    Clinical breast cancer, 2007, Volume: 7, Issue:11

    Topics: Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Canada; Chemotherapy, Adjuvant; Female; Humans; Middle Aged; Postmenopause; Quality of Life; Research Design; Risk Assessment

2007
Double-blind, randomized placebo controlled trial of fulvestrant compared with exemestane after prior nonsteroidal aromatase inhibitor therapy in postmenopausal women with hormone receptor-positive, advanced breast cancer: results from EFECT.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Apr-01, Volume: 26, Issue:10

    Topics: Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Double-Blind Method; Estradiol; Female; Fulvestrant; Humans; Kaplan-Meier Estimate; Neoplasm Recurrence, Local; Placebos; Postmenopause; Quality of Life; Receptors, Estrogen

2008
Treatment of advanced hormone-sensitive breast cancer in postmenopausal women with exemestane alone or in combination with celecoxib.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Mar-10, Volume: 26, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Breast Neoplasms; Celecoxib; Disease Progression; Female; Humans; Middle Aged; Neoplasms, Hormone-Dependent; Postmenopause; Pyrazoles; Sulfonamides; Tissue Distribution; Treatment Outcome

2008
Estrogen suppression in premenopausal women following 8 weeks of treatment with exemestane and triptorelin versus triptorelin alone.
    Breast cancer research and treatment, 2009, Volume: 113, Issue:3

    Topics: Adult; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Double-Blind Method; Estradiol; Estrone; Female; Gonadotropins; Humans; Ovary; Premenopause; Triptorelin Pamoate; Young Adult

2009
Benefit from exemestane as extended adjuvant therapy after 5 years of adjuvant tamoxifen: intention-to-treat analysis of the National Surgical Adjuvant Breast And Bowel Project B-33 trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Apr-20, Volume: 26, Issue:12

    Topics: Administration, Oral; Androstadienes; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Drug Administration Schedule; Female; Humans; Middle Aged; Neoplasm Staging; Neoplasms, Hormone-Dependent; Quality of Life; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Treatment Outcome

2008
Switching to letrozole or exemestane improves hot flushes, mood and quality of life in tamoxifen intolerant women.
    British journal of cancer, 2008, May-06, Volume: 98, Issue:9

    Topics: Affect; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Arthralgia; Breast Neoplasms; Chemotherapy, Adjuvant; Cross-Over Studies; Estrogen Receptor Modulators; Female; Hot Flashes; Humans; Letrozole; Middle Aged; Nitriles; Patient Participation; Patient Selection; Postmenopause; Prospective Studies; Quality of Life; Research Design; Sample Size; Surveys and Questionnaires; Tamoxifen; Triazoles

2008
The minimal effective exemestane dose for endocrine activity in advanced breast cancer.
    European journal of cancer (Oxford, England : 1990), 1997, Volume: 33, Issue:4

    Topics: Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Dehydroepiandrosterone Sulfate; Depression, Chemical; Double-Blind Method; Drug Administration Schedule; Estradiol; Estrogen Antagonists; Estrone; Female; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Middle Aged; Postmenopause; Sex Hormone-Binding Globulin

1997
Third-line hormonal treatment with exemestane in postmenopausal patients with advanced breast cancer progressing on aminoglutethimide: a phase II multicentre multinational study. Exemestane Study Group.
    European journal of cancer (Oxford, England : 1990), 1997, Volume: 33, Issue:11

    Topics: Aged; Aged, 80 and over; Aminoglutethimide; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Disease Progression; Female; Humans; Middle Aged; Postmenopause; Treatment Outcome

1997
In vivo inhibition of aromatization by exemestane, a novel irreversible aromatase inhibitor, in postmenopausal breast cancer patients.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:9

    Topics: Administration, Oral; Androstadienes; Androstenedione; Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Carbon Radioisotopes; Estradiol; Estrogens; Estrone; Female; Humans; Postmenopause; Tritium

1998
Endocrine and clinical effects of exemestane (PNU 155971), a novel steroidal aromatase inhibitor, in postmenopausal breast cancer patients: a phase I study.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1997, Volume: 3, Issue:7

    Topics: Aged; Alprostadil; Androgens; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Dinoprostone; Dose-Response Relationship, Drug; Drug Administration Schedule; Estradiol; Estrone; Female; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Lymphatic Metastasis; Middle Aged; Neoplasm Metastasis; Postmenopause

1997
Safety, activity and estrogen inhibition by exemestane in postmenopausal women with advanced breast cancer: a phase I study.
    Anti-cancer drugs, 1998, Volume: 9, Issue:8

    Topics: Adult; Aged; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Dizziness; Dose-Response Relationship, Drug; Estrogen Antagonists; Estrogens; Female; Headache; Humans; Middle Aged; Nausea; Postmenopause

1998
Multicenter, phase II trial of exemestane as third-line hormonal therapy of postmenopausal women with metastatic breast cancer. Aromasin Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1999, Volume: 17, Issue:11

    Topics: Adult; Aged; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Chemotherapy, Adjuvant; Estrogens; Female; Humans; Middle Aged; Postmenopause

1999
Exemestane is superior to megestrol acetate after tamoxifen failure in postmenopausal women with advanced breast cancer: results of a phase III randomized double-blind trial. The Exemestane Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:7

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Breast Neoplasms; Disease Progression; Double-Blind Method; Female; Humans; Megestrol Acetate; Middle Aged; Neoplasm Recurrence, Local; Pain; Postmenopause; Quality of Life; Survival Analysis; Tamoxifen; Treatment Outcome

2000
Activity of exemestane in metastatic breast cancer after failure of nonsteroidal aromatase inhibitors: a phase II trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:11

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chi-Square Distribution; Female; Humans; Middle Aged; Neoplasm Metastasis; Palliative Care; Postmenopause; Statistics, Nonparametric; Survival Analysis; Treatment Outcome

2000
High activity and tolerability demonstrated for exemestane in postmenopausal women with metastatic breast cancer who had previously failed on tamoxifen treatment.
    European journal of cancer (Oxford, England : 1990), 2000, Volume: 36, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Estrogens; Female; Humans; Middle Aged; Neoplasm Metastasis; Postmenopause; Tamoxifen; Treatment Failure

2000
Exemestane improves survival compared with megoestrol acetate in postmenopausal patients with advanced breast cancer who have failed on tamoxifen. results Of a double-blind randomised phase III trial.
    European journal of cancer (Oxford, England : 1990), 2000, Volume: 36 Suppl 4

    Topics: Androstadienes; Antineoplastic Agents; Breast Neoplasms; Double-Blind Method; Enzyme Inhibitors; Female; Humans; Megestrol Acetate; Postmenopause; Survival Analysis; Tamoxifen; Treatment Failure

2000
Cost-effectiveness analysis of exemestane compared with megestrol in patients with advanced breast carcinoma.
    Cancer, 2001, Feb-01, Volume: 91, Issue:3

    Topics: Androstadienes; Antineoplastic Agents; Breast Neoplasms; Cohort Studies; Cost-Benefit Analysis; Drug Costs; Female; Humans; Megestrol

2001
Exemestane improves survival in metastatic breast cancer: results of a phase III randomized study.
    Clinical breast cancer, 2000, Volume: 1 Suppl 1

    Topics: Administration, Oral; Aged; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Double-Blind Method; Female; Humans; Megestrol Acetate; Middle Aged; Neoplasm Metastasis; Postmenopause; Survival Analysis; Treatment Outcome

2000
Promising results with exemestane in the first-line treatment of metastatic breast cancer: a randomized phase II EORTC trial with a tamoxifen control.
    Clinical breast cancer, 2000, Volume: 1 Suppl 1

    Topics: Administration, Oral; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Disease Progression; Female; Humans; Neoplasm Metastasis; Tamoxifen; Treatment Outcome

2000

Other Studies

306 other study(ies) available for aromasil and Breast Neoplasms

ArticleYear
Exemestane metabolites: Synthesis, stereochemical elucidation, biochemical activity and anti-proliferative effects in a hormone-dependent breast cancer cell line.
    European journal of medicinal chemistry, 2014, Nov-24, Volume: 87

    Topics: Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Cell Proliferation; Cell Survival; Chemistry Techniques, Synthetic; Dose-Response Relationship, Drug; Estradiol; Humans; MCF-7 Cells; Receptors, Estrogen; Stereoisomerism; Structure-Activity Relationship; Time Factors

2014
Exploring new chemical functionalities to improve aromatase inhibition of steroids.
    Bioorganic & medicinal chemistry, 2016, 06-15, Volume: 24, Issue:12

    Topics: Androstanes; Androstenedione; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Cell Line, Tumor; Female; Humans; Molecular Docking Simulation; Steroids; Structure-Activity Relationship

2016
4th generation nonsteroidal aromatase inhibitors: An iterative SAR-guided design, synthesis, and biological evaluation towards picomolar dual binding inhibitors.
    European journal of medicinal chemistry, 2022, Oct-05, Volume: 240

    Topics: Aromatase; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Receptors, Estrogen; Triazoles

2022
From clinical trials to clinical practice: the use of everolimus and exemestane in the treatment of hormone receptor-positive metastatic breast cancer: real-world data.
    Journal of chemotherapy (Florence, Italy), 2022, Volume: 34, Issue:3

    Topics: Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Everolimus; Female; Humans; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Retrospective Studies

2022
Characterization of Cytosolic Glutathione
    Drug metabolism and disposition: the biological fate of chemicals, 2021, Volume: 49, Issue:12

    Topics: Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chromatography, Liquid; Cysteine; Cytosol; Estrogens; Glutathione Transferase; Hepatobiliary Elimination; Humans; Inactivation, Metabolic; Liver; Protein Isoforms; Receptors, Estrogen

2021
Real-World Outcomes of Everolimus and Exemestane for the Treatment of Metastatic Hormone Receptor-Positive Breast Cancer in Patients Previously Treated With CDK4/6 Inhibitors.
    Clinical breast cancer, 2022, Volume: 22, Issue:2

    Topics: Adolescent; Adult; Aged; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Everolimus; Female; Humans; Middle Aged; Quality of Life; Receptor, ErbB-2; Retrospective Studies; Treatment Outcome

2022
Real-Life Analysis of Efficacy and Safety of Everolimus Plus Exemestane in Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor-2-Negative Metastatic Breast Cancer Patients: A Turkish Oncology Group (TOG) Study.
    Cancer investigation, 2022, Volume: 40, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Everolimus; Female; Humans; Middle Aged; Neoplasm Metastasis; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Retrospective Studies; Survival Analysis; Treatment Outcome; Turkey

2022
Magnetic mesoporous silica nanoparticles as a theranostic approach for breast cancer: Loading and release of the poorly soluble drug exemestane.
    International journal of pharmaceutics, 2022, May-10, Volume: 619

    Topics: Androstadienes; Breast Neoplasms; Contrast Media; Drug Carriers; Drug Liberation; Female; Humans; Nanoparticles; Porosity; Precision Medicine; Silicon Dioxide

2022
Everolimus and exemestane in hormone receptor positive advanced breast cancer: A comprehensive cancer center's experience.
    Bulletin du cancer, 2022, Volume: 109, Issue:6

    Topics: Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Everolimus; Female; Humans; Receptor, ErbB-2

2022
Influence of Glutathione-S-Transferase A1*B Allele on the Metabolism of the Aromatase Inhibitor, Exemestane, in Human Liver Cytosols and in Patients Treated With Exemestane.
    The Journal of pharmacology and experimental therapeutics, 2022, Volume: 382, Issue:3

    Topics: Alleles; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Cytosol; Female; Glutathione; Glutathione Transferase; Humans; Liver

2022
Statin use in patients with hormone receptor-positive metastatic breast cancer treated with everolimus and exemestane.
    Cancer medicine, 2023, Volume: 12, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Everolimus; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Receptor, ErbB-2; Retrospective Studies

2023
An Exemestane Derivative, Oxymestane-D1, as a New Multi-Target Steroidal Aromatase Inhibitor for Estrogen Receptor-Positive (ER
    Molecules (Basel, Switzerland), 2023, Jan-12, Volume: 28, Issue:2

    Topics: Aromatase Inhibitors; Breast Neoplasms; Drug Resistance, Neoplasm; Estrogen Receptor alpha; Female; Humans; MCF-7 Cells; Receptors, Estrogen

2023
Efficacy of Alternative Dose Regimens of Exemestane in Postmenopausal Women With Stage 0 to II Estrogen Receptor-Positive Breast Cancer: A Randomized Clinical Trial.
    JAMA oncology, 2023, 05-01, Volume: 9, Issue:5

    Topics: Aged; Breast Neoplasms; Double-Blind Method; Estradiol; Female; Humans; Ki-67 Antigen; Postmenopause; Receptors, Estrogen; Receptors, Progesterone

2023
Cognitive function among women with breast cancer receiving endocrine therapy: what are the impacts?
    JNCI cancer spectrum, 2023, 03-01, Volume: 7, Issue:2

    Topics: Breast Neoplasms; Cognition; Female; Humans; Postmenopause; Tamoxifen

2023
Effects of tamoxifen and exemestane on cognitive function in postmenopausal patients with breast cancer.
    JNCI cancer spectrum, 2023, 03-01, Volume: 7, Issue:2

    Topics: Breast Neoplasms; Cognition; Female; Follow-Up Studies; Humans; Postmenopause; Prospective Studies; Tamoxifen

2023
Polymer-lipid hybrid nanoparticles of exemestane for improved oral bioavailability and anti-tumor efficacy: An extensive preclinical investigation.
    International journal of pharmaceutics, 2023, Jul-25, Volume: 642

    Topics: Androstadienes; Animals; Biological Availability; Breast Neoplasms; Female; Humans; Lipids; Mice; Nanoparticles; Polymers; Rats; Rats, Wistar

2023
Acute generalized exanthematous pustulosis induced by exemestane during adjuvant radiotherapy for breast cancer.
    Medicina clinica, 2023, Dec-07, Volume: 161, Issue:11

    Topics: Acute Generalized Exanthematous Pustulosis; Androstadienes; Breast Neoplasms; Female; Humans; Radiotherapy, Adjuvant

2023
Boronic-targeted albumin-shell oily-core nanocapsules for synergistic aromatase inhibitor/herbal breast cancer therapy.
    Materials science & engineering. C, Materials for biological applications, 2019, Volume: 105

    Topics: Albumins; Androstadienes; Antineoplastic Agents, Phytogenic; Aromatase Inhibitors; Boron; Breast Neoplasms; Female; Hesperidin; Humans; MCF-7 Cells; Nanocapsules; Phospholipids

2019
Breast Cancer Chemoprevention: A Practical Guide for the Primary Care Provider.
    Journal of women's health (2002), 2020, Volume: 29, Issue:1

    Topics: Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Chemoprevention; Decision Making, Shared; Female; Humans; Middle Aged; Physician-Patient Relations; Primary Health Care; Raloxifene Hydrochloride; Risk Assessment; Selective Estrogen Receptor Modulators; Tamoxifen

2020
Absolute Improvements in Freedom From Distant Recurrence to Tailor Adjuvant Endocrine Therapies for Premenopausal Women: Results From TEXT and SOFT.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2020, 04-20, Volume: 38, Issue:12

    Topics: Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials, Phase III as Topic; Female; Humans; Neoplasm Recurrence, Local; Ovariectomy; Ovary; Premenopause; Randomized Controlled Trials as Topic; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Triptorelin Pamoate

2020
Endocrine-based therapy versus chemotherapy in advanced breast cancer.
    The Lancet. Oncology, 2019, Volume: 20, Issue:12

    Topics: Androstadienes; Breast Neoplasms; Capecitabine; Female; Gonadotropin-Releasing Hormone; Humans; Piperazines; Pyridines

2019
Adjuvant endocrine therapy for premenopausal women: risk stratification, type and duration.
    Breast (Edinburgh, Scotland), 2019, Volume: 48 Suppl 1

    Topics: Adult; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Disease-Free Survival; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Middle Aged; Neoplasm Recurrence, Local; Ovary; Premenopause; Randomized Controlled Trials as Topic; Risk Assessment; Tamoxifen; Time Factors; Young Adult

2019
High ctDNA molecule numbers relate with poor outcome in advanced ER+, HER2- postmenopausal breast cancer patients treated with everolimus and exemestane.
    Molecular oncology, 2020, Volume: 14, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Circulating Tumor DNA; Everolimus; Female; High-Throughput Nucleotide Sequencing; Humans; Middle Aged; Mutation, Missense; Neoplasm Metastasis; Postmenopause; Progression-Free Survival; Receptor, ErbB-2; Receptors, Estrogen; Retrospective Studies

2020
Multiple Pigmented Lesions of the Breast Following Ipsilateral Breast Carcinoma.
    The American journal of medicine, 2020, Volume: 133, Issue:8

    Topics: Aged; Androstadienes; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Breast Neoplasms; Carbamates; Female; Humans; Mastectomy; Mastectomy, Segmental; Melanoma; Neoplasms, Radiation-Induced; Neoplasms, Second Primary; Neoplasms, Unknown Primary; Radiotherapy; Skin Neoplasms; Sulfonamides

2020
Efficacy and safety of everolimus plus exemestane in patients with HR+, HER2- advanced breast cancer progressing on/after prior endocrine therapy in routine clinical practice: Primary results from the non-interventional study, STEPAUT.
    Breast (Edinburgh, Scotland), 2020, Volume: 50

    Topics: Aged; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Austria; Breast Neoplasms; Everolimus; Female; Humans; Postmenopause; Practice Patterns, Physicians'; Progression-Free Survival; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone

2020
Severe Cellular Immunodeficiency Triggered by the CDK4/6 Inhibitor Palbociclib.
    Clinical breast cancer, 2020, Volume: 20, Issue:2

    Topics: Aged; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Fatal Outcome; Female; Humans; Immunocompromised Host; Lymphocyte Count; Lymphopenia; Piperazines; Pneumocystis; Pneumonia, Pneumocystis; Pyridines; Severity of Illness Index; Trimethoprim, Sulfamethoxazole Drug Combination

2020
Medication Use to Reduce Risk of Breast Cancer.
    American family physician, 2020, 03-15, Volume: 101, Issue:6

    Topics: Adult; Anastrozole; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Female; Humans; Medication Adherence; Raloxifene Hydrochloride; Risk Factors; Selective Estrogen Receptor Modulators

2020
A case of exemestane induced pseudocellulitis.
    Dermatologic therapy, 2020, Volume: 33, Issue:4

    Topics: Androstadienes; Breast Neoplasms; Erythema; Female; Humans; Middle Aged; Vasculitis, Leukocytoclastic, Cutaneous

2020
Structural Recognition and Binding Pattern Analysis of Human Topoisomerase II Alpha with Steroidal Drugs: In Silico Study to Switchover the Cancer Treatment.
    Asian Pacific journal of cancer prevention : APJCP, 2020, May-01, Volume: 21, Issue:5

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Computer Simulation; DNA Topoisomerases, Type II; Female; Humans; Letrozole; Protein Conformation

2020
[A prospective study of bone loss in early stage postmenopausal breast cancer treated with aromatase inhibitors].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2020, May-23, Volume: 42, Issue:5

    Topics: Anastrozole; Androstadienes; Aromatase Inhibitors; Bone Density; Breast Neoplasms; Humans; Letrozole; Postmenopause; Prospective Studies

2020
Lack of everolimus diffusion in pleural fluid during pleural progression of breast cancer: A case report.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2021, Volume: 27, Issue:1

    Topics: Aged; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Disease Progression; Everolimus; Female; Humans; Piperazines; Pyridines

2021
Functional genomics based on germline genome-wide association studies of endocrine therapy for breast cancer.
    Pharmacogenomics, 2020, Volume: 21, Issue:9

    Topics: Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Female; Genome-Wide Association Study; Genomics; Germ Cells; Humans; Selective Estrogen Receptor Modulators; Tamoxifen

2020
Breast Cancer Risk-Reducing Medications.
    JAMA, 2020, 07-21, Volume: 324, Issue:3

    Topics: Adult; Age Factors; Anastrozole; Androstadienes; Anticarcinogenic Agents; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Raloxifene Hydrochloride; Risk Factors; Selective Estrogen Receptor Modulators; Tamoxifen

2020
Overestimation of Late Distant Recurrences in High-Risk Patients With ER-Positive Breast Cancer: Validity and Accuracy of the CTS5 Risk Score in the TEAM and IDEAL Trials.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2020, 10-01, Volume: 38, Issue:28

    Topics: Aged; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials, Phase III as Topic; Cohort Studies; Female; Humans; Letrozole; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Proportional Hazards Models; Randomized Controlled Trials as Topic; Receptors, Estrogen; Reproducibility of Results; Risk Assessment; Tamoxifen

2020
PEGylated Nanoliposomes Potentiated Oral Combination Therapy for Effective Cancer Treatment.
    Current drug delivery, 2020, Volume: 17, Issue:9

    Topics: Administration, Oral; Androstadienes; Animals; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Biological Availability; Breast Neoplasms; Cell Line, Tumor; Complement Activation; Drug Synergism; Female; Gastrointestinal Absorption; Humans; Liposomes; Lycopene; Mice; Nanoparticles; Polyethylene Glycols; Proof of Concept Study; Tissue Distribution; Tumor Microenvironment; Xenograft Model Antitumor Assays

2020
Variation in the UGT2B17 genotype, exemestane metabolism and menopause-related toxicities in the CCTG MAP.3 trial.
    Breast cancer research and treatment, 2020, Volume: 183, Issue:3

    Topics: Androstadienes; Breast Neoplasms; Female; Genotype; Glucuronosyltransferase; Humans; Menopause; Minor Histocompatibility Antigens

2020
Case report: 5-year progression free survival and complete liver response in a patient with metastatic breast cancer treated with everolimus plus exemestane.
    Medicine, 2020, Jul-31, Volume: 99, Issue:31

    Topics: Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Lobular; Everolimus; Female; Humans; Liver Neoplasms; Middle Aged; Premenopause; Progression-Free Survival

2020
Concomitant fulvestrant with reirradiation for unresectable locoregional recurrent estrogen receptor positive (ER+) breast cancer: A case report and narrative review.
    Medicine, 2020, Jul-24, Volume: 99, Issue:30

    Topics: Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Estrogen Receptor Antagonists; Female; Fulvestrant; Humans; Lymphatic Metastasis; Mastectomy, Modified Radical; Middle Aged; Narrative Medicine; Neoplasm Recurrence, Local; Re-Irradiation; Receptors, Estrogen

2020
Exemestane induced cholestatic liver injury - A case report.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2021, Volume: 27, Issue:4

    Topics: Aged; Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Chemical and Drug Induced Liver Injury; Cholestasis; Female; Humans

2021
Everolimus Plus Exemestane Treatment in Patients with Metastatic Hormone Receptor-Positive Breast Cancer Previously Treated with CDK4/6 Inhibitor Therapy.
    The oncologist, 2021, Volume: 26, Issue:2

    Topics: Adult; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclin-Dependent Kinase 4; Everolimus; Female; Hormones; Humans; Receptor, ErbB-2; Retrospective Studies; Sirolimus

2021
Optimal Treatment Duration of Neoadjuvant Endocrine Therapy for Women Aged 60 Years or Older with Estrogen Receptor-Positive, HER2-Negative Invasive Breast Cancer.
    Journal of Nippon Medical School = Nippon Ika Daigaku zasshi, 2021, Sep-01, Volume: 88, Issue:4

    Topics: Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Duration of Therapy; Female; Humans; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Prospective Studies; Receptor, ErbB-2; Receptors, Estrogen

2021
Implications of Tamoxifen Resistance in Palbociclib Efficacy for Patients with Hormone Receptor-Positive, HER2-Negative Metastatic Breast Cancer: Subgroup Analyses of KCSG-BR15-10 (YoungPEARL).
    Cancer research and treatment, 2021, Volume: 53, Issue:3

    Topics: Adult; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials, Phase II as Topic; Female; Humans; Mastectomy; Middle Aged; Multicenter Studies as Topic; Neoplasm Recurrence, Local; Piperazines; Progression-Free Survival; Protein Kinase Inhibitors; Pyridines; Randomized Controlled Trials as Topic; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen

2021
COVID-19-induced toxic epidermal necrolysis.
    Clinical and experimental dermatology, 2021, Volume: 46, Issue:5

    Topics: Adrenal Cortex Hormones; Androstadienes; Aromatase Inhibitors; Body Surface Area; Bone Neoplasms; Brain Neoplasms; Breast Neoplasms; COVID-19; Dexamethasone; Emollients; Female; Hospitalization; Humans; Liver Neoplasms; Middle Aged; Palliative Care; SARS-CoV-2; Stevens-Johnson Syndrome

2021
Dynamic changes of CTCs in patients with metastatic HR(+)/HER2(-) breast cancer receiving salvage treatment with everolimus/exemestane.
    Cancer chemotherapy and pharmacology, 2021, Volume: 87, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Everolimus; Female; Humans; Middle Aged; Neoplasm Metastasis; Neoplastic Cells, Circulating; Prognosis; Prospective Studies; Receptor, ErbB-2; Salvage Therapy; Treatment Outcome

2021
Safety and efficacy of everolimus (EVE) plus exemestane (EXE) in postmenopausal women with locally advanced or metastatic breast cancer: final results from EVEREXES.
    Breast cancer research and treatment, 2021, Volume: 188, Issue:1

    Topics: Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Asia; Breast Neoplasms; Everolimus; Female; Humans; Neoplasm Recurrence, Local; Postmenopause; Receptor, ErbB-2; Sirolimus

2021
Chemical inhibitor anticancer drugs regulate mechanical properties and cytoskeletal structure of non-invasive and invasive breast cancer cell lines: Study of effects of Letrozole, Exemestane, and Everolimus.
    Biochemical and biophysical research communications, 2021, 08-06, Volume: 565

    Topics: Androstadienes; Antineoplastic Agents; Breast Neoplasms; Cell Survival; Cytoskeleton; Everolimus; Female; Humans; Letrozole; Tumor Cells, Cultured

2021
Differential biological effects of aromatase inhibitors: Apoptosis, autophagy, senescence and modulation of the hormonal status in breast cancer cells.
    Molecular and cellular endocrinology, 2021, 11-01, Volume: 537

    Topics: Anastrozole; Androstadienes; Apoptosis; Aromatase Inhibitors; Autophagy; Biomarkers; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cellular Senescence; Cyclins; Early Growth Response Protein 3; Estrogens; Female; Gene Expression Regulation, Neoplastic; Hormones; Humans; Letrozole; Receptors, Androgen; Receptors, Estrogen; Signal Transduction; Tumor Suppressor Proteins

2021
Osteonecrosis of the Jaw in a Breast Cancer Patient Treated with Everolimus and a Single Dose of Zoledronic Acid.
    The breast journal, 2017, Volume: 23, Issue:5

    Topics: Androstadienes; Bone Density Conservation Agents; Bone Neoplasms; Breast Neoplasms; Cone-Beam Computed Tomography; Diagnosis, Differential; Everolimus; Female; Humans; Jaw Diseases; Mastectomy; Middle Aged; Osteonecrosis

2017
Dose intensity and efficacy of the combination of everolimus and exemestane (EVE/EXE) in a real-world population of hormone receptor-positive (ER+/PgR+), HER2-negative advanced breast cancer (ABC) patients: a multicenter Italian experience.
    Breast cancer research and treatment, 2017, Volume: 163, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Disease-Free Survival; Drug-Related Side Effects and Adverse Reactions; Everolimus; Female; Humans; Italy; Middle Aged; Neoplasm Staging; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Stomatitis

2017
Exemestane and Its Active Metabolite 17-Hydroexemestane Induce UDP-Glucuronosyltransferase (UGT) 2B17 Expression in Breast Cancer Cells.
    The Journal of pharmacology and experimental therapeutics, 2017, Volume: 361, Issue:3

    Topics: Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Cell Line, Tumor; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glucuronosyltransferase; Humans; MCF-7 Cells; Minor Histocompatibility Antigens

2017
FGFR2 amplification in metastatic hormone-positive breast cancer and response to an mTOR inhibitor.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2017, 08-01, Volume: 28, Issue:8

    Topics: Adult; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Estradiol; Everolimus; Female; Fulvestrant; Gene Amplification; Goserelin; Humans; Piperazines; Pyridines; Receptor, Fibroblast Growth Factor, Type 2; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; TOR Serine-Threonine Kinases

2017
Switch to exemestane effective in early breast cancer.
    The Lancet. Oncology, 2017, Volume: 18, Issue:6

    Topics: Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Disease Progression; Disease-Free Survival; Drug Substitution; Female; Humans; Randomized Controlled Trials as Topic; Time Factors; Treatment Outcome

2017
Role of the UGT2B17 deletion in exemestane pharmacogenetics.
    The pharmacogenomics journal, 2018, Volume: 18, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Female; Gene Deletion; Glucuronosyltransferase; Humans; Middle Aged; Minor Histocompatibility Antigens; Pharmacogenetics

2018
COX2 induction: a mechanism of endocrine breast cancer resistance?
    Breast cancer research and treatment, 2017, Volume: 165, Issue:2

    Topics: Aged; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Biomarkers; Breast Neoplasms; Case-Control Studies; Chromatography, Liquid; Cyclooxygenase 2; Dinoprostone; Drug Monitoring; Drug Resistance, Neoplasm; Female; Humans; Middle Aged; Postmenopause; Retrospective Studies; Tandem Mass Spectrometry

2017
Treatment Efficacy, Adherence, and Quality of Life Among Women Younger Than 35 Years in the International Breast Cancer Study Group TEXT and SOFT Adjuvant Endocrine Therapy Trials.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, Sep-20, Volume: 35, Issue:27

    Topics: Adult; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Female; Humans; Premenopause; Quality of Life; Receptor, ErbB-2; Tamoxifen; Treatment Outcome

2017
Adjuvant endocrine therapy for premenopausal women: Type and duration.
    Breast (Edinburgh, Scotland), 2017, Volume: 34 Suppl 1

    Topics: Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Drug Administration Schedule; Female; Humans; Premenopause; Receptor, ErbB-2; Receptors, Estrogen; Tamoxifen; Time Factors

2017
Efficacy and safety of Everolimus and Exemestane in hormone-receptor positive (HR+) human-epidermal-growth-factor negative (HER2-) advanced breast cancer patients: New insights beyond clinical trials. The EVA study.
    Breast (Edinburgh, Scotland), 2017, Volume: 35

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Breast Neoplasms; Everolimus; Female; Follow-Up Studies; Humans; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Receptor, ErbB-2

2017
Tuning up adjuvant endocrine therapy: the TEAM trial.
    The Lancet. Oncology, 2017, Volume: 18, Issue:9

    Topics: Androstadienes; Breast Neoplasms; Female; Follow-Up Studies; Humans; Postmenopause; Tamoxifen

2017
Emerging combination endocrine therapies for advanced breast cancer.
    The breast journal, 2018, Volume: 24, Issue:2

    Topics: Adult; Androstadienes; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Combined Modality Therapy; Everolimus; Female; Humans; Lung Neoplasms; Receptor, ErbB-2; Receptors, Estrogen

2018
Progressive Restrictive Strabismus in an Adult Woman.
    JAMA ophthalmology, 2017, Dec-01, Volume: 135, Issue:12

    Topics: Adenocarcinoma; Androstadienes; Antineoplastic Agents; Brachytherapy; Breast Neoplasms; Female; Humans; Middle Aged; Oculomotor Muscles; Orbital Neoplasms; Strabismus

2017
Shell-crosslinked zein nanocapsules for oral codelivery of exemestane and resveratrol in breast cancer therapy.
    Nanomedicine (London, England), 2017, Volume: 12, Issue:24

    Topics: Administration, Oral; Androstadienes; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Cross-Linking Reagents; Drug Combinations; Drug Liberation; Female; Glutaral; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Male; Mice; Nanocapsules; Particle Size; Rats, Wistar; Resveratrol; Solubility; Stilbenes; Surface Properties; Tissue Distribution; Zein

2017
Curcumin dietary supplements and everolimus-based cancer treatment.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2018, 01-01, Volume: 29, Issue:1

    Topics: Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Curcumin; Dietary Supplements; Everolimus; Female; Humans; Middle Aged

2018
Comparison of Changes in the Lipid Profiles of Eastern Chinese Postmenopausal Women With Early-Stage Breast Cancer Treated With Different Aromatase Inhibitors: A Retrospective Study.
    Clinical pharmacology in drug development, 2018, Volume: 7, Issue:8

    Topics: Aged; Anastrozole; Androstadienes; Aromatase Inhibitors; Asian People; Breast Neoplasms; China; Female; Humans; Letrozole; Lipid Metabolism; Lipids; Middle Aged; Postmenopause; Retrospective Studies

2018
[Efficacy and Safety of Everolimus plus Exemetane in Postmenopausal Endocrine-Responsive Metastatic Breast Cancer Patients].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2017, Volume: 44, Issue:12

    Topics: Aged; Aged, 80 and over; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Endocrine System; Everolimus; Female; Humans; Middle Aged; Neoplasm Metastasis; Postmenopause

2017
Improvement of treatment outcomes after implementation of comprehensive pharmaceutical care in breast cancer patients receiving everolimus and exemestane.
    Die Pharmazie, 2018, Feb-01, Volume: 73, Issue:2

    Topics: Adult; Aged; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Disease-Free Survival; Everolimus; Female; Humans; Kaplan-Meier Estimate; Middle Aged; Patient Compliance; Pharmaceutical Services; Postmenopause; Quality of Life; Stomatitis; Treatment Failure

2018
Patient-reported predictors of early treatment discontinuation: treatment-related symptoms and health-related quality of life among postmenopausal women with primary breast cancer randomized to anastrozole or exemestane on NCIC Clinical Trials Group (CCTG
    Breast cancer research and treatment, 2018, Volume: 169, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Androstadienes; Breast Neoplasms; Combined Modality Therapy; Female; Humans; Kaplan-Meier Estimate; Medication Adherence; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Patient Reported Outcome Measures; Postmenopause; Quality of Life; Randomized Controlled Trials as Topic

2018
Adjuvant aromatase inhibition: more options for patients.
    The Lancet. Oncology, 2018, Volume: 19, Issue:4

    Topics: Anastrozole; Androstadienes; Aromatase; Breast Neoplasms; Humans; Letrozole; Tamoxifen

2018
Predictive markers for efficacy of everolimus plus exemestane in patients with luminal HER2-negative metastatic breast cancer.
    Medical oncology (Northwood, London, England), 2018, Mar-08, Volume: 35, Issue:4

    Topics: Adult; Aged; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Disease-Free Survival; Everolimus; Female; Humans; Ki-67 Antigen; Middle Aged; PTEN Phosphohydrolase; Receptor, ErbB-2; Receptors, Estrogen; Ribosomal Protein S6 Kinases

2018
Cost-Effectiveness of Second-Line Endocrine Therapies in Postmenopausal Women with Hormone Receptor-positive and Human Epidermal Growth Factor Receptor 2-negative Metastatic Breast Cancer in Japan.
    PharmacoEconomics, 2018, Volume: 36, Issue:9

    Topics: Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cost-Benefit Analysis; Everolimus; Female; Fulvestrant; Health Care Costs; Humans; Japan; Markov Chains; Middle Aged; Models, Economic; Postmenopause; Quality-Adjusted Life Years; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Toremifene

2018
Lactoferrin-decorated vs PEGylated zein nanospheres for combined aromatase inhibitor and herbal therapy of breast cancer.
    Expert opinion on drug delivery, 2018, Volume: 15, Issue:9

    Topics: Androstadienes; Animals; Aromatase Inhibitors; Breast Neoplasms; Drug Carriers; Female; Humans; Lactoferrin; Luteolin; Mice; Mice, Inbred BALB C; Nanospheres; Particle Size; Phospholipids; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Zein

2018
Mutational Profile of Metastatic Breast Cancer Tissue in Patients Treated with Exemestane Plus Everolimus.
    BioMed research international, 2018, Volume: 2018

    Topics: Aged; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; DNA Mutational Analysis; Everolimus; Female; Genes, Neoplasm; Humans; Middle Aged; Neoplasm Recurrence, Local; Phosphatidylinositol 3-Kinases; Prospective Studies; Retrospective Studies; Sirolimus

2018
Identification and Quantification of Novel Major Metabolites of the Steroidal Aromatase Inhibitor, Exemestane.
    Drug metabolism and disposition: the biological fate of chemicals, 2018, Volume: 46, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Chromatography, Liquid; Cysteine; Female; Glucuronides; Humans; Metabolic Detoxication, Phase II; Middle Aged; Tandem Mass Spectrometry

2018
Everolimus-induced pulmonary toxicity: Findings on 18F-FDG PET/CT imaging.
    Medicine, 2018, Volume: 97, Issue:40

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Breast Neoplasms; Everolimus; Female; Fluorodeoxyglucose F18; Glycolysis; Humans; Lung Diseases, Interstitial; Middle Aged; Positron Emission Tomography Computed Tomography; TOR Serine-Threonine Kinases; Tumor Burden

2018
Clinical outcomes comparison of 10 years versus 5 years of adjuvant endocrine therapy in patients with early breast cancer.
    BMC cancer, 2018, Oct-12, Volume: 18, Issue:1

    Topics: Age of Onset; Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Letrozole; Postmenopause; Prospective Studies; Tamoxifen; Treatment Outcome

2018
A New Genetic Risk Score to Predict the Outcome of Locally Advanced or Metastatic Breast Cancer Patients Treated With First-Line Exemestane: Results From a Prospective Study.
    Clinical breast cancer, 2019, Volume: 19, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Biomarkers, Tumor; Breast Neoplasms; DNA Repair; Female; Humans; Male; Middle Aged; Polymorphism, Genetic; Prospective Studies; Receptors, Estrogen; Reproducibility of Results; Risk; Signal Transduction; Survival Analysis

2019
A real-life study on the implementation and effectiveness of exemestane plus everolimus per hospital type in patients with advanced breast cancer. A study of the Southeast Netherlands Advanced Breast Cancer registry.
    Breast (Edinburgh, Scotland), 2019, Volume: 44

    Topics: Aged; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Disease-Free Survival; Everolimus; Female; Humans; Middle Aged; Netherlands; Receptors, Estrogen; Receptors, Progesterone; Treatment Outcome

2019
Dissecting the predictive value of MAPK/AKT/estrogen-receptor phosphorylation axis in primary breast cancer to treatment response for tamoxifen over exemestane: a Translational Report of the Intergroup Exemestane Study (IES)-PathIES.
    Breast cancer research and treatment, 2019, Volume: 175, Issue:1

    Topics: Adult; Aged; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Female; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Middle Aged; Mitogen-Activated Protein Kinases; Neoplasm Grading; Neoplasm Staging; Phosphorylation; Prognosis; Proto-Oncogene Proteins c-akt; Receptors, Estrogen; Tamoxifen; Treatment Outcome

2019
Treatment after Progression on Fulvestrant among Metastatic Breast Cancer Patients in Clinical Practice: a Multicenter, Retrospective Study.
    Scientific reports, 2019, 02-08, Volume: 9, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Breast Neoplasms; Capecitabine; Disease Progression; Everolimus; Female; Fulvestrant; Humans; Middle Aged; Multivariate Analysis; Neoplasm Metastasis; Receptor, ErbB-2; Retrospective Studies; Risk Factors; Survival Analysis; Treatment Outcome

2019
Exemestane may be less detrimental than letrozole to bone health in women homozygous for the UGT2B17*2 gene deletion.
    Breast cancer research and treatment, 2019, Volume: 175, Issue:2

    Topics: Androstadienes; Aromatase Inhibitors; Bone and Bones; Bone Density; Bone Remodeling; Breast Neoplasms; Female; Gene Deletion; Genetic Association Studies; Genotype; Glucuronosyltransferase; Humans; Letrozole; Middle Aged; Minor Histocompatibility Antigens; Pharmacogenetics; Postmenopause; Tamoxifen

2019
Observational study of everolimus plus exemestane in postmenopausal women with hormone receptor-positive, HER2-negative advanced breast cancer.
    Acta oncologica (Stockholm, Sweden), 2019, Volume: 58, Issue:3

    Topics: Aged; Aged, 80 and over; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Everolimus; Female; Follow-Up Studies; Humans; Middle Aged; Postmenopause; Prognosis; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Survival Rate

2019
Fulvestrant 500 mg Versus Exemestane in Postmenopausal Women With Metastatic Breast Cancer Resistant to Adjuvant Nonsteroidal Aromatase Inhibitors in Clinical Practice: A Multicenter Retrospective Study.
    Clinical breast cancer, 2019, Volume: 19, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Fulvestrant; Humans; Middle Aged; Neoplasm Metastasis; Postmenopause; Prognosis; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Retrospective Studies; Survival Rate

2019
Genetics to epigenetics: targeting histone deacetylases in hormone receptor-positive metastatic breast cancer.
    The Lancet. Oncology, 2019, Volume: 20, Issue:6

    Topics: Androstadienes; Breast Neoplasms; Double-Blind Method; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Postmenopause

2019
HDAC inhibitors tested in phase III trial.
    Nature reviews. Clinical oncology, 2019, Volume: 16, Issue:8

    Topics: Androstadienes; Breast Neoplasms; Double-Blind Method; Histone Deacetylase Inhibitors; Humans; Postmenopause

2019
Exemestane Plus Ovarian Function Suppression Is the Best Adjuvant Treatment of Premenopausal Women With Endocrine-Responsive Breast Cancer at Higher Risk of Relapse and With HER2-Negative Tumors.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2019, 07-20, Volume: 37, Issue:21

    Topics: Androstadienes; Breast Neoplasms; Female; Humans; Neoplasm Recurrence, Local; Premenopause

2019
Radiation recall syndrome in a patient with breast cancer, after introduction of everolimus.
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2019, Volume: 23, Issue:5

    Topics: Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Carcinoma, Lobular; Estrogens; Everolimus; Female; Humans; Lymphatic Irradiation; Lymphocele; Mastectomy; Middle Aged; Neoplasms, Hormone-Dependent; Progesterone; Radiodermatitis; Radiotherapy, Intensity-Modulated; TOR Serine-Threonine Kinases

2019
Prospective Study of Drug-induced Interstitial Lung Disease in Advanced Breast Cancer Patients Receiving Everolimus Plus Exemestane.
    Targeted oncology, 2019, Volume: 14, Issue:4

    Topics: Adult; Aged; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Everolimus; Female; Humans; Lung Diseases, Interstitial; Male; Middle Aged; Prospective Studies; Respiratory Function Tests

2019
Unexpected ovarian activity in premenopausal breast cancer survivors treated with exemestane and GnRH analogues.
    The breast journal, 2019, Volume: 25, Issue:6

    Topics: Adult; Androstadienes; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cancer Survivors; Chemotherapy, Adjuvant; Drug Monitoring; Estradiol; Female; Gonadotropin-Releasing Hormone; Humans; Ovarian Function Tests; Ovary; Premenstrual Syndrome; Tamoxifen; Uterine Hemorrhage

2019
IGF-1R inhibition: right direction, wrong pathway?
    The Lancet. Oncology, 2013, Volume: 14, Issue:3

    Topics: Androstadienes; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Breast Neoplasms; Estradiol; Female; Fulvestrant; Humans; Neoplasms, Hormone-Dependent

2013
Poly(D, L-lactide-co-glycolide)/montmorillonite nanoparticles for improved oral delivery of exemestane.
    Journal of microencapsulation, 2013, Volume: 30, Issue:5

    Topics: Androstadienes; Antineoplastic Agents; Bentonite; Breast Neoplasms; Caco-2 Cells; Cell Line, Tumor; Drug Carriers; Female; Humans; Lactic Acid; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer

2013
Effect of aromatase inhibitors on bone mineral density in a Japanese breast cancer population.
    Drug metabolism and pharmacokinetics, 2013, Volume: 28, Issue:5

    Topics: Aged; Aged, 80 and over; Anastrozole; Androstadienes; Aromatase Inhibitors; Asian People; Bone Density; Breast Neoplasms; Diphosphonates; Female; Humans; Letrozole; Middle Aged; Nitriles; Postmenopause; Retrospective Studies; Triazoles

2013
Specific adverse events predict survival benefit in patients treated with tamoxifen or aromatase inhibitors: an international tamoxifen exemestane adjuvant multinational trial analysis.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Jun-20, Volume: 31, Issue:18

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials, Phase III as Topic; Disease-Free Survival; Female; Follow-Up Studies; Genital Diseases, Female; Humans; International Cooperation; Middle Aged; Multicenter Studies as Topic; Musculoskeletal Diseases; Outcome Assessment, Health Care; Prognosis; Proportional Hazards Models; Randomized Controlled Trials as Topic; Tamoxifen; Vasomotor System

2013
Treatment-emergent effects may predict benefit from endocrine therapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Jun-20, Volume: 31, Issue:18

    Topics: Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Mammary Glands, Human; Outcome Assessment, Health Care; Postmenopause; Tamoxifen

2013
Oral ulcers in patients with advanced breast cancer receiving everolimus: a case series report on clinical presentation and management.
    Oral surgery, oral medicine, oral pathology and oral radiology, 2013, Volume: 116, Issue:2

    Topics: Aged; Androstadienes; Anti-Inflammatory Agents; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Dexamethasone; Everolimus; Female; Follow-Up Studies; Glucocorticoids; Humans; Middle Aged; Oral Ulcer; Prospective Studies; Recurrence; Sirolimus; Stomatitis; Stomatitis, Aphthous; TOR Serine-Threonine Kinases; Treatment Outcome

2013
Eradication of breast cancer with bone metastasis by autologous formalin-fixed tumor vaccine (AFTV) combined with palliative radiation therapy and adjuvant chemotherapy: a case report.
    World journal of surgical oncology, 2013, Jun-04, Volume: 11

    Topics: Anastrozole; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Autoantigens; Bone Neoplasms; Breast Neoplasms; Cancer Vaccines; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Diphosphonates; Epirubicin; Female; Fixatives; Fluorouracil; Formaldehyde; Humans; Imidazoles; Magnetic Resonance Imaging; Mastectomy; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Prognosis; Radiotherapy Dosage; Tomography, Emission-Computed, Single-Photon; Triazoles; Zoledronic Acid

2013
Effect of visceral metastases on the efficacy and safety of everolimus in postmenopausal women with advanced breast cancer: subgroup analysis from the BOLERO-2 study.
    European journal of cancer (Oxford, England : 1990), 2013, Volume: 49, Issue:12

    Topics: Aged; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials, Phase III as Topic; Everolimus; Exanthema; Fatigue; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Middle Aged; Multicenter Studies as Topic; Neoplasm Metastasis; Placebos; Postmenopause; Prognosis; Randomized Controlled Trials as Topic; Receptor, ErbB-2; Receptors, Steroid; Sirolimus; Stomatitis; Treatment Outcome; Viscera

2013
Entinostat plus exemestane has activity in ER+ advanced breast cancer.
    Cancer discovery, 2013, Volume: 3, Issue:7

    Topics: Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Benzamides; Breast Neoplasms; Disease-Free Survival; Female; Humans; Pyridines; Receptors, Estrogen

2013
Combination endocrine treatments unproven in breast cancer.
    The Lancet. Oncology, 2013, Volume: 14, Issue:10

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Humans; Nitriles; Triazoles

2013
Liquid chromatography tandem mass spectrometry determination of free and conjugated estrogens in breast cancer patients before and after exemestane treatment.
    Analytica chimica acta, 2014, Jan-02, Volume: 806

    Topics: Androstadienes; Antineoplastic Agents; Breast Neoplasms; Chromatography, High Pressure Liquid; Estradiol Congeners; Estrogens; Female; Humans; Postmenopause; Solid Phase Extraction; Tandem Mass Spectrometry

2014
Long-term outcome of neoadjuvant endocrine therapy with aromatase inhibitors in elderly women with hormone receptor-positive breast cancer.
    Annals of surgical oncology, 2014, Volume: 21, Issue:5

    Topics: Aged; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Chemotherapy, Adjuvant; Female; Follow-Up Studies; Humans; Letrozole; Neoadjuvant Therapy; Neoplasm Grading; Neoplasm Staging; Nitriles; Postmenopause; Prognosis; Receptor, ErbB-2; Retrospective Studies; Survival Rate; Tamoxifen; Time Factors; Triazoles

2014
Biomarker changes associated with the development of resistance to aromatase inhibitors (AIs) in estrogen receptor-positive breast cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2014, Volume: 25, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Androstadienes; Aromatase Inhibitors; Biomarkers, Tumor; Breast Neoplasms; Drug Resistance, Neoplasm; Female; Humans; Insulin Receptor Substrate Proteins; Ki-67 Antigen; Letrozole; Middle Aged; Neoplasm Recurrence, Local; Nitriles; PTEN Phosphohydrolase; Receptor, ErbB-2; Receptor, IGF Type 1; Receptors, Estrogen; Receptors, Progesterone; Retrospective Studies; Stathmin; Tamoxifen; Triazoles

2014
The bone substudy of MA.27: does bone make a difference?
    The Lancet. Oncology, 2014, Volume: 15, Issue:4

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Bone Density; Breast Neoplasms; Female; Humans; Neoplasms, Hormone-Dependent; Nitriles; Triazoles

2014
VAV3 mediates resistance to breast cancer endocrine therapy.
    Breast cancer research : BCR, 2014, May-28, Volume: 16, Issue:3

    Topics: Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Biomarkers, Tumor; Breast; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Resistance, Neoplasm; Enzyme Activators; ErbB Receptors; Erlotinib Hydrochloride; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Genetic Association Studies; Genetic Variation; Humans; Indazoles; Letrozole; MCF-7 Cells; Nitriles; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-vav; Quinazolines; RNA Interference; RNA, Small Interfering; Tamoxifen; Toremifene; Triazoles

2014
Hormone therapy in premenopausal women with early-stage breast cancer.
    The New England journal of medicine, 2014, Jul-10, Volume: 371, Issue:2

    Topics: Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Humans; Tamoxifen; Triptorelin Pamoate

2014
[BOLERO -- another remarkable step in treatment of breast cancer].
    Magyar onkologia, 2014, Volume: 58, Issue:2

    Topics: Adult; Aged; Androstadienes; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials, Phase III as Topic; Disease Progression; Disease-Free Survival; Drug Administration Schedule; Drug Resistance, Neoplasm; Everolimus; Female; Humans; Kaplan-Meier Estimate; Middle Aged; Molecular Targeted Therapy; Postmenopause; Randomized Controlled Trials as Topic; Receptors, Estrogen; Receptors, Progesterone; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases; Trastuzumab; Treatment Outcome; Vinblastine; Vinorelbine

2014
Cost-effectiveness analysis of everolimus plus exemestane versus exemestane alone for treatment of hormone receptor positive metastatic breast cancer.
    Breast cancer research and treatment, 2014, Volume: 147, Issue:2

    Topics: Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cost-Benefit Analysis; Disease Progression; Disease-Free Survival; Everolimus; Female; Humans; Markov Chains; Neoplasm Metastasis; Sirolimus

2014
Mutational analysis of PI3K/AKT signaling pathway in tamoxifen exemestane adjuvant multinational pathology study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014, Sep-20, Volume: 32, Issue:27

    Topics: Adult; Aged; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Class I Phosphatidylinositol 3-Kinases; Disease-Free Survival; DNA Mutational Analysis; DNA, Neoplasm; Female; Humans; Kaplan-Meier Estimate; Middle Aged; Mutation; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Tamoxifen

2014
Case report: A breast cancer patient treated with GcMAF, sonodynamic therapy and hormone therapy.
    Anticancer research, 2014, Volume: 34, Issue:8

    Topics: Androstadienes; Breast Neoplasms; Combined Modality Therapy; Female; Humans; Macrophage-Activating Factors; Middle Aged; Ultrasonic Therapy; Vitamin D-Binding Protein

2014
A new combination therapy for premenopausal breast cancer.
    The Lancet. Oncology, 2014, Volume: 15, Issue:8

    Topics: Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Humans; Premenopause; Tamoxifen

2014
Cost of adverse events during treatment with everolimus plus exemestane or single-agent chemotherapy in patients with advanced breast cancer in Western Europe.
    Journal of medical economics, 2014, Volume: 17, Issue:12

    Topics: Androstadienes; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Databases, Factual; Europe; Everolimus; Female; Humans; Models, Economic; Sirolimus

2014
Radiation-recall dermatitis with the everolimus/exemestane combination ten years after adjuvant whole-breast radiotherapy.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2014, Volume: 112, Issue:3

    Topics: Androstadienes; Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Drug Therapy, Combination; Everolimus; Female; Humans; Liver Neoplasms; Middle Aged; Neoplasms, Second Primary; Radiodermatitis; Radiotherapy, Adjuvant; Sirolimus

2014
More treatment options for women with hormone receptor-positive breast cancer: guideline update, studies lead to advances in care.
    Cancer, 2014, Oct-01, Volume: 120, Issue:19

    Topics: Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Drug Administration Schedule; Estrogen Receptor Modulators; Evidence-Based Medicine; Female; Humans; Neoplasm Staging; Ovary; Postmenopause; Practice Guidelines as Topic; Premenopause; Randomized Controlled Trials as Topic; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen

2014
Longitudinal trends in utilization of endocrine therapies for breast cancer: an international comparison.
    Journal of clinical pharmacy and therapeutics, 2015, Volume: 40, Issue:1

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Australia; Breast Neoplasms; Developed Countries; Drug Utilization Review; England; Female; France; Humans; Internationality; Letrozole; Longitudinal Studies; Netherlands; Nitriles; Scandinavian and Nordic Countries; Tamoxifen; Triazoles

2015
Primary Hormonal Therapy for Elderly Breast Cancer Patients: Single Institution Experience.
    Gynecologic and obstetric investigation, 2015, Volume: 80, Issue:1

    Topics: Aged; Aged, 80 and over; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Breast Neoplasms; Estradiol; Female; Fulvestrant; Humans; Letrozole; Nitriles; Receptors, Estrogen; Retrospective Studies; Spain; Tamoxifen; Treatment Outcome; Triazoles

2015
Everolimus in acute kidney injury in a patient with breast cancer: a case report.
    Journal of medical case reports, 2014, Nov-25, Volume: 8

    Topics: Acute Kidney Injury; Aged; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Creatinine; Drug Therapy, Combination; Everolimus; Female; Humans; Sirolimus

2014
Perfecting breast-cancer treatment--incremental gains and musculoskeletal pains.
    The New England journal of medicine, 2015, Jan-29, Volume: 372, Issue:5

    Topics: Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Tamoxifen; Triptorelin Pamoate

2015
No pain, no gain: a fallacy so far.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Jan-20, Volume: 33, Issue:3

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Musculoskeletal System; Nitriles; Triazoles; Vasomotor System

2015
Case records of the Massachusetts General Hospital. Case 1-2015. A 66-year-old woman with metastatic breast cancer after endocrine therapy.
    The New England journal of medicine, 2015, Jan-08, Volume: 372, Issue:2

    Topics: Aged; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinoma, Ductal, Breast; Class I Phosphatidylinositol 3-Kinases; Diagnosis, Differential; Female; Humans; Lung Neoplasms; Lymph Nodes; Magnetic Resonance Imaging; Mastectomy, Segmental; Mutation; Nitriles; Phosphatidylinositol 3-Kinases; Receptors, Estrogen; Receptors, Progesterone; Risk Factors; Triazoles

2015
Integration of a prognostic gene module with a drug sensitivity module to identify drugs that could be repurposed for breast cancer therapy.
    Computers in biology and medicine, 2015, Volume: 61

    Topics: Androstadienes; Breast Neoplasms; Databases, Genetic; Female; Gene Ontology; Humans; Pharmacogenetics; Prognosis; Tamoxifen

2015
New cell culture model for aromatase inhibitor-resistant breast cancer shows sensitivity to fulvestrant treatment and cross-resistance between letrozole and exemestane.
    International journal of oncology, 2015, Volume: 46, Issue:4

    Topics: Androstadienes; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Cell Culture Techniques; Cell Proliferation; Drug Resistance, Neoplasm; Estradiol; Female; Fulvestrant; Gene Expression Regulation, Neoplastic; Humans; Letrozole; MCF-7 Cells; Models, Biological; Nitriles; Tamoxifen; Triazoles

2015
Uptake of exemestane chemoprevention in postmenopausal women at increased risk for breast cancer.
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 2016, Volume: 25, Issue:1

    Topics: Aged; Androstadienes; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Intraductal, Noninfiltrating; Female; Follow-Up Studies; Humans; Middle Aged; Neoplasm Staging; Postmenopause; Prognosis; Retrospective Studies; Risk Assessment; Selective Estrogen Receptor Modulators

2016
Synergistic effects of combined treatment with simvastatin and exemestane on MCF-7 human breast cancer cells.
    Molecular medicine reports, 2015, Volume: 12, Issue:1

    Topics: Androstadienes; Apoptosis; Breast Neoplasms; Cell Cycle Checkpoints; Cell Proliferation; Drug Synergism; Female; Humans; MCF-7 Cells; Simvastatin

2015
Role of obesity on the efficacy of exemestane plus ovarian suppression in hormone receptor-positive premenopausal breast cancer.
    Future oncology (London, England), 2015, Volume: 11, Issue:6

    Topics: Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Obesity; Ovary; Receptors, Estrogen; Treatment Outcome

2015
Primary chemoprevention of breast cancer: Are the adverse effects too burdensome?
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2015, Jun-16, Volume: 187, Issue:9

    Topics: Adult; Aged; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Chemoprevention; Female; Humans; Middle Aged; Risk Assessment; Tamoxifen

2015
Breast cancer risk reduction therapy: the low-hanging fruit.
    Journal of the National Comprehensive Cancer Network : JNCCN, 2015, Volume: 13, Issue:4

    Topics: Anastrozole; Androstadienes; Aromatase Inhibitors; Breast; Breast Neoplasms; Carcinoma in Situ; Female; Humans; Hyperplasia; Nitriles; Practice Patterns, Physicians'; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Tamoxifen; Triazoles

2015
The introduction of generic aromatase inhibitors and treatment adherence among Medicare D enrollees.
    Journal of the National Cancer Institute, 2015, Volume: 107, Issue:8

    Topics: Aged; Aged, 80 and over; Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Cohort Studies; Drug Costs; Drugs, Generic; Evaluation Studies as Topic; Female; Humans; Letrozole; Medicare; Medication Adherence; Nitriles; Non-Randomized Controlled Trials as Topic; Poverty; Triazoles; United States

2015
Adjuvant treatments of breast cancer increase the risk of depressive disorders: A population-based study.
    Journal of affective disorders, 2015, Aug-15, Volume: 182

    Topics: Adult; Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Depressive Disorder; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Letrozole; Middle Aged; Nitriles; Population Surveillance; Proportional Hazards Models; Retrospective Studies; Risk; Taiwan; Tamoxifen; Trastuzumab; Triazoles

2015
Aromatase Inhibitor-Mediated Downregulation of INrf2 (Keap1) Leads to Increased Nrf2 and Resistance in Breast Cancer.
    Molecular cancer therapeutics, 2015, Volume: 14, Issue:7

    Topics: Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Down-Regulation; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Immunoblotting; Intracellular Signaling Peptides and Proteins; Kelch-Like ECH-Associated Protein 1; Letrozole; MCF-7 Cells; Molecular Structure; NF-E2-Related Factor 2; Nitriles; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Triazoles; Ubiquitination

2015
Everolimus use and associated factors among post-menopausal women with hormonal receptor positive/human epidermal growth factor receptor 2 negative metastatic breast cancer.
    Current medical research and opinion, 2015, Volume: 31, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Everolimus; Female; Humans; Liver Neoplasms; Middle Aged; Receptor, ErbB-2; Receptors, Estrogen; Retrospective Studies

2015
Everolimus plus exemestane versus bevacizumab-based chemotherapy for second-line treatment of hormone receptor-positive metastatic breast cancer in Greece: An economic evaluation study.
    BMC health services research, 2015, Aug-05, Volume: 15

    Topics: Androstadienes; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Breast Neoplasms; Cost-Benefit Analysis; Everolimus; Female; Greece; Humans; Middle Aged; Quality-Adjusted Life Years

2015
The role of censoring on progression free survival: oncologist discretion advised.
    European journal of cancer (Oxford, England : 1990), 2015, Volume: 51, Issue:16

    Topics: Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Bias; Breast Neoplasms; Data Interpretation, Statistical; Disease-Free Survival; Endpoint Determination; Everolimus; Female; Humans; Kaplan-Meier Estimate; Randomized Controlled Trials as Topic; Reproducibility of Results; Research Design; Time Factors; Treatment Failure

2015
Everolimus in Metastatic Breast Cancer: Clinical Experience as a Late Treatment Line.
    Oncology, 2015, Volume: 89, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Case-Control Studies; Estradiol; Everolimus; Female; Follow-Up Studies; Fulvestrant; Humans; Letrozole; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Nitriles; Prognosis; Retrospective Studies; Survival Rate; Tamoxifen; Triazoles

2015
[Everolimus plus Exemestane in Postmenopausal Metastatic Breast Cancer Patients].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2015, Volume: 42, Issue:10

    Topics: Aged; Aged, 80 and over; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Everolimus; Female; Humans; Middle Aged; Postmenopause; Retrospective Studies; Treatment Outcome

2015
Exemestane metabolites suppress growth of estrogen receptor-positive breast cancer cells by inducing apoptosis and autophagy: A comparative study with Exemestane.
    The international journal of biochemistry & cell biology, 2015, Volume: 69

    Topics: Androstadienes; Antineoplastic Agents; Apoptosis; Autophagy; Breast Neoplasms; Cell Proliferation; Cell Shape; Cell Survival; Drug Screening Assays, Antitumor; Female; Humans; MCF-7 Cells; Membrane Potential, Mitochondrial; Receptors, Estrogen; Testosterone

2015
Associations between genetic variants and the effect of letrozole and exemestane on bone mass and bone turnover.
    Breast cancer research and treatment, 2015, Volume: 154, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Alleles; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Biomarkers; Bone and Bones; Bone Density; Bone Remodeling; Breast Neoplasms; Female; Genetic Association Studies; Genetic Variation; Genotype; Humans; Letrozole; Middle Aged; Nitriles; Polymorphism, Single Nucleotide; Postmenopause; Triazoles

2015
Gene expression alterations associated with outcome in aromatase inhibitor-treated ER+ early-stage breast cancer patients.
    Breast cancer research and treatment, 2015, Volume: 154, Issue:3

    Topics: Aged; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Cell Line, Tumor; Chemotherapy, Adjuvant; Drug Resistance, Neoplasm; Eye Proteins; Female; Gene Expression Regulation, Neoplastic; Humans; Letrozole; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Peptides; Receptors, Estrogen; Retrospective Studies; RGS Proteins; Transcription Factors; Treatment Outcome; Trefoil Factor-3; Triazoles

2015
ESR1 Mutations Prevalent in Some Breast Cancers.
    Cancer discovery, 2016, Volume: 6, Issue:2

    Topics: Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials, Phase III as Topic; Congresses as Topic; Estrogen Receptor alpha; Everolimus; Female; Humans; Mutation; Treatment Outcome

2016
[Efficacies of aromatase inhibitors in the treatment of hormone dependent metastatic breast cancer in postmenopausal women: a report of 148 cases].
    Zhonghua yi xue za zhi, 2015, Jun-09, Volume: 95, Issue:22

    Topics: Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Disease-Free Survival; Female; Hormones; Humans; Letrozole; Neoplasm Metastasis; Nitriles; Postmenopause; Triazoles

2015
Self-renewal of CD133(hi) cells by IL6/Notch3 signalling regulates endocrine resistance in metastatic breast cancer.
    Nature communications, 2016, Feb-09, Volume: 7

    Topics: AC133 Antigen; Anastrozole; Androstadienes; Animals; Antigens, CD; Antineoplastic Agents, Hormonal; Bone Neoplasms; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Cell Line, Tumor; Cell Self Renewal; Drug Resistance, Neoplasm; Estradiol; Female; Flow Cytometry; Fulvestrant; Gene Expression Regulation, Neoplastic; Glycoproteins; Humans; In Vitro Techniques; Interleukin-6; Letrozole; Leuprolide; MCF-7 Cells; Mice, Inbred NOD; Mice, SCID; Neoplasm Metastasis; Neoplasm Transplantation; Neoplastic Stem Cells; Nitriles; Oxidative Phosphorylation; Peptides; Real-Time Polymerase Chain Reaction; Receptor, Notch3; Receptors, Estrogen; Receptors, Notch; Signal Transduction; Tamoxifen; Triazoles

2016
Theoretical Study of the Mechanism of Exemestane Hydroxylation Catalyzed by Human Aromatase Enzyme.
    The journal of physical chemistry. B, 2016, Apr-07, Volume: 120, Issue:13

    Topics: Androstadienes; Androstenedione; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Hydroxylation; Molecular Docking Simulation; Thermodynamics

2016
Absolute Benefit of Adjuvant Endocrine Therapies for Premenopausal Women With Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Early Breast Cancer: TEXT and SOFT Trials.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016, 07-01, Volume: 34, Issue:19

    Topics: Adult; Aged; Androstadienes; Breast Neoplasms; Clinical Trials as Topic; Female; Humans; Middle Aged; Neoplasm Recurrence, Local; Ovary; Proportional Hazards Models; Receptor, ErbB-2; Receptors, Estrogen; Tamoxifen

2016
Adjuvant endocrine therapy in premenopausal women with breast cancer.
    Clinical advances in hematology & oncology : H&O, 2015, Volume: 13, Issue:10

    Topics: Aged; Aged, 80 and over; Androstadienes; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Hormone Replacement Therapy; Humans; Middle Aged; Postmenopause; Quality of Life; Tamoxifen

2015
Are SOFT and TEXT results practice changing and how?
    Breast (Edinburgh, Scotland), 2016, Volume: 27

    Topics: Adult; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials, Phase III as Topic; Female; Humans; Ovary; Premenopause; Randomized Controlled Trials as Topic; Receptor, ErbB-2; Tamoxifen

2016
[Factors related to adjuvant ovarian function suppression in premenopausal breast cancer patients].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2016, May-23, Volume: 38, Issue:5

    Topics: Adjuvants, Immunologic; Adult; Age Factors; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Estrogen Antagonists; Female; Humans; Middle Aged; Ovary; Premenopause; Tamoxifen

2016
Complete response and long-term survival of leptomeningeal carcinomatosis from breast cancer with maintenance endocrine therapy.
    BMJ case reports, 2016, Jun-02, Volume: 2016

    Topics: Aged; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Humans; Letrozole; Meningeal Carcinomatosis; Methotrexate; Nitriles; Spinal Neoplasms; Triazoles

2016
[An Elderly Patient with Metastatic Breast Cancer Who Developed Severe Adverse Events such as Stomatitis and Interstitial Pneumonia after Everolimus plus Exemestane Treatment].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2016, Volume: 43, Issue:6

    Topics: Aged, 80 and over; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Everolimus; Female; Humans; Lung Diseases, Interstitial; Neoplasm Metastasis; Stomatitis; Thoracic Wall

2016
Circulating oxysterol metabolites as potential new surrogate markers in patients with hormone receptor-positive breast cancer: Results of the OXYTAM study.
    The Journal of steroid biochemistry and molecular biology, 2017, Volume: 169

    Topics: Adult; Aged; Androstadienes; Aromatase; Aromatase Inhibitors; Biomarkers; Body Mass Index; Breast Neoplasms; Cholestanes; Cholesterol; Feasibility Studies; Female; Gas Chromatography-Mass Spectrometry; Hormones; Humans; Letrozole; Middle Aged; Neoplasm Metastasis; Nitriles; Oxidative Stress; Oxysterols; Pilot Projects; Prognosis; Prospective Studies; Reproducibility of Results; Signal Transduction; Tamoxifen; Triazoles

2017
Safety analysis, association with response and previous treatments of everolimus and exemestane in 181 metastatic breast cancer patients: A multicenter Italian experience.
    Breast (Edinburgh, Scotland), 2016, Volume: 29

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Drug-Related Side Effects and Adverse Reactions; Everolimus; Female; Humans; Italy; Middle Aged; Neoplasm Metastasis; Proportional Hazards Models; Receptor, ErbB-2; Regression Analysis; Retrospective Studies; Treatment Outcome

2016
Should We Offer Medication to Reduce Breast Cancer Risk?: Grand Rounds Discussion From Beth Israel Deaconess Medical Center.
    Annals of internal medicine, 2016, 08-02, Volume: 165, Issue:3

    Topics: Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Clinical Decision-Making; Female; Humans; Middle Aged; Practice Guidelines as Topic; Primary Health Care; Raloxifene Hydrochloride; Risk Assessment; Risk Reduction Behavior; Selective Estrogen Receptor Modulators; Tamoxifen

2016
Microbial-catalysed derivatization of anti-cancer drug exemestane and cytotoxicity of resulting metabolites against human breast adenocarcinoma cell line (MCF-7) in vitro.
    Steroids, 2016, Volume: 115

    Topics: Androstadienes; Antineoplastic Agents; Aspergillus niger; Breast Neoplasms; Cell Survival; Cunninghamella; Fermentation; Gibberella; Humans; MCF-7 Cells; Molecular Structure

2016
Polymorphisms in drug-metabolizing enzymes and steady-state exemestane concentration in postmenopausal patients with breast cancer.
    The pharmacogenomics journal, 2017, Volume: 17, Issue:6

    Topics: Androstadienes; Antineoplastic Agents; Breast Neoplasms; Cytochrome P-450 CYP3A; Female; Genotyping Techniques; Humans; Middle Aged; Pharmacogenomic Testing; Pharmacogenomic Variants; Polymorphism, Single Nucleotide; Postmenopause; Precision Medicine; Predictive Value of Tests

2017
Falsely elevated serum oestradiol due to exemestane therapy.
    Annals of clinical biochemistry, 2017, Volume: 54, Issue:3

    Topics: Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Contraindications; Drug Dosage Calculations; Estradiol; False Positive Reactions; Female; Humans; Immunoassay; Middle Aged; Molecular Mimicry; Monitoring, Physiologic

2017
[A Case of Recurrent Breast Cancer with Bone Metastasis Successfully Treated with Everolimus and Exemestane Therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2017, Volume: 44, Issue:2

    Topics: Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Everolimus; Female; Humans; Middle Aged; Recurrence; Treatment Outcome

2017
Reduced expression of cyclooxygenase-2 in primary breast cancer.
    Journal of the National Cancer Institute, 2008, Jul-16, Volume: 100, Issue:14

    Topics: Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Celecoxib; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Down-Regulation; Drug Therapy, Combination; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Pyrazoles; Reverse Transcriptase Polymerase Chain Reaction; Sulfonamides; Treatment Failure

2008
Characterization of the weak estrogen receptor alpha agonistic activity of exemestane.
    Breast cancer research and treatment, 2009, Volume: 116, Issue:3

    Topics: Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Cell Proliferation; Drug Resistance, Neoplasm; Estrogen Receptor alpha; Female; Gene Expression Profiling; Humans; Microarray Analysis; Nitriles; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Triazoles; Tumor Cells, Cultured

2009
Screening and management of osteoporosis in breast cancer patients on aromatase inhibitors.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2008, Volume: 14, Issue:3

    Topics: Absorptiometry, Photon; Adult; Aged; Aged, 80 and over; Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Bone Density Conservation Agents; Bone Diseases, Metabolic; Breast Neoplasms; Female; Humans; Letrozole; Middle Aged; Nitriles; Osteoporosis; Retrospective Studies; Triazoles

2008
Aromatase inhibition versus placebo.
    Clinical breast cancer, 2008, Volume: 8, Issue:4

    Topics: Androstadienes; Aromatase Inhibitors; Bone Density; Breast Neoplasms; Cholesterol, HDL; Clinical Trials as Topic; Female; Humans

2008
Exacerbation of diabetes related to exemestane treatment.
    Acta oncologica (Stockholm, Sweden), 2008, Volume: 47, Issue:6

    Topics: Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Blood Glucose; Breast Neoplasms; Clinical Trials, Phase III as Topic; Diabetes Mellitus, Type 2; Female; Humans; Insulin Resistance; Middle Aged; Neoplasm Recurrence, Local; Thoracic Wall

2008
Exemestane-induced subclinical hypothyroidism : a case report.
    Clinical drug investigation, 2008, Volume: 28, Issue:10

    Topics: Aged; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Female; Follow-Up Studies; Humans; Hypothyroidism; Thyroxine

2008
[A case of recurrent breast cancer with liver metastasis responding to exemestane].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:5

    Topics: Adult; Androstadienes; Antineoplastic Agents; Biomarkers, Tumor; Breast Neoplasms; Female; Humans; Liver Neoplasms; Recurrence; Tomography, X-Ray Computed

2009
Predictors of response to exemestane as primary endocrine therapy in estrogen receptor-positive breast cancer.
    Cancer science, 2009, Volume: 100, Issue:11

    Topics: Aged; Aged, 80 and over; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Histone Acetyltransferases; Humans; Immunohistochemistry; Ki-67 Antigen; Nuclear Receptor Coactivator 3; Phosphorylation; Receptors, Estrogen; Receptors, Progesterone; Trans-Activators

2009
Visual impairment in myopic patients with breast cancer receiving adjuvant therapy with aromatase inhibitors.
    Clinical breast cancer, 2009, Volume: 9, Issue:3

    Topics: Adjuvants, Pharmaceutic; Androstadienes; Aromatase Inhibitors; Asian People; Breast Neoplasms; Female; Humans; Middle Aged; Myopia; Vision, Low; Visual Acuity

2009
Evaluation of plasma and tissue estrogen suppression with third-generation aromatase inhibitors: of relevance to clinical understanding?
    The Journal of steroid biochemistry and molecular biology, 2010, Feb-28, Volume: 118, Issue:4-5

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Estrogens; Female; Humans; Letrozole; Nitriles; Postmenopause; Triazoles

2010
Potential role of UGT pharmacogenetics in cancer treatment and prevention: focus on tamoxifen and aromatase inhibitors.
    Drug metabolism reviews, 2010, Volume: 42, Issue:1

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Letrozole; Nitriles; Pharmacogenetics; Receptors, Estrogen; Tamoxifen; Triazoles

2010
Impact of aromatase inhibitors on bone health in breast cancer patients.
    The Journal of steroid biochemistry and molecular biology, 2010, Feb-28, Volume: 118, Issue:4-5

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Bone and Bones; Bone Density; Bone Diseases, Metabolic; Breast Neoplasms; Calcium; Diphosphonates; Female; Humans; Letrozole; Nitriles; Triazoles; Vitamin D

2010
Severe prolonged cholestatic hepatitis caused by exemestane.
    Breast cancer research and treatment, 2010, Volume: 121, Issue:3

    Topics: Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Female; Humans; Middle Aged

2010
Molecular characterization of aromatase inhibitor-resistant, tamoxifen-resistant and LTEDaro cell lines.
    The Journal of steroid biochemistry and molecular biology, 2010, Feb-28, Volume: 118, Issue:4-5

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Letrozole; Nitriles; Tamoxifen; Triazoles

2010
[A case of recurrent breast cancer with extensive liver metastasis successfully treated with endocrine therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:13

    Topics: Androstadienes; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Humans; Letrozole; Liver Neoplasms; Medroxyprogesterone; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Tamoxifen; Toremifene; Triazoles

2009
Cognitive functioning of postmenopausal breast cancer patients before adjuvant systemic therapy, and its association with medical and psychological factors.
    Critical reviews in oncology/hematology, 2010, Volume: 76, Issue:2

    Topics: Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Chemotherapy, Adjuvant; Cognition; Cognition Disorders; Comorbidity; Diabetes Mellitus; Female; Humans; Hypertension; Intelligence Tests; Middle Aged; Multicenter Studies as Topic; Neuropsychological Tests; Postmenopause; Randomized Controlled Trials as Topic; Risk Factors; Tamoxifen

2010
Effects of tamoxifen and exemestane on cognitive functioning of postmenopausal patients with breast cancer: results from the neuropsychological side study of the tamoxifen and exemestane adjuvant multinational trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Mar-10, Volume: 28, Issue:8

    Topics: Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Case-Control Studies; Cognition Disorders; Female; Humans; Middle Aged; Netherlands; Postmenopause; Prospective Studies; Randomized Controlled Trials as Topic; Selective Estrogen Receptor Modulators; Tamoxifen

2010
Increased estrogen sulfatase (STS) and 17beta-hydroxysteroid dehydrogenase type 1(17beta-HSD1) following neoadjuvant aromatase inhibitor therapy in breast cancer patients.
    Breast cancer research and treatment, 2010, Volume: 120, Issue:3

    Topics: Aged; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Biomarkers, Tumor; Breast Neoplasms; Carcinoma, Ductal, Breast; Clinical Trials, Phase II as Topic; Combined Modality Therapy; Estradiol Dehydrogenases; Estrogens; Female; Humans; Ki-67 Antigen; Mastectomy; Middle Aged; Multicenter Studies as Topic; Neoadjuvant Therapy; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Postmenopause; Receptors, Steroid; Sulfatases

2010
Increased intratumoral androgens in human breast carcinoma following aromatase inhibitor exemestane treatment.
    Endocrine-related cancer, 2010, Volume: 17, Issue:2

    Topics: Aged; Androgens; Androstadienes; Aromatase Inhibitors; Blotting, Western; Breast; Breast Neoplasms; Carcinoma, Ductal, Breast; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Chromatography, Liquid; Female; Humans; Immunohistochemistry; Microarray Analysis; Middle Aged; Reverse Transcriptase Polymerase Chain Reaction; Tandem Mass Spectrometry

2010
Metastatic breast carcinoma presenting with profound hypocalcemia.
    Southern medical journal, 2010, Volume: 103, Issue:5

    Topics: Adult; Androstadienes; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinoma; Epilepsy, Tonic-Clonic; Female; Goserelin; Humans; Hypocalcemia; Neoplasm Metastasis

2010
Variations in locoregional therapy in postmenopausal patients with early breast cancer treated in different countries.
    The British journal of surgery, 2010, Volume: 97, Issue:5

    Topics: Adult; Aged; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Body Mass Index; Breast Neoplasms; Clinical Protocols; Combined Modality Therapy; Epidemiologic Methods; Female; Humans; Mastectomy; Middle Aged; Multicenter Studies as Topic; Patient Selection; Postmenopause; Randomized Controlled Trials as Topic; Tamoxifen

2010
Differential diagnosis of lung nodules: breast cancer metastases and lung tuberculosis.
    Le infezioni in medicina, 2010, Volume: 18, Issue:1

    Topics: Aged; Androstadienes; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinoma, Ductal, Breast; Diagnosis, Differential; Estrogens; Female; Humans; Lung Neoplasms; Lymphatic Metastasis; Neoplasms, Hormone-Dependent; Progesterone; Recurrence; Tamoxifen; Tomography, X-Ray Computed; Tuberculosis, Pulmonary

2010
Death due to liver failure during endocrine therapy for premenopausal breast cancer.
    Acta oncologica (Stockholm, Sweden), 2010, Volume: 49, Issue:6

    Topics: Adult; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemical and Drug Induced Liver Injury; Diphenhydramine; Drug Synergism; Estrogen Receptor Modulators; Fatal Outcome; Female; Hepatitis, Alcoholic; Humans; Hypnotics and Sedatives; Liver Failure, Acute; Middle Aged; Premenopause; Self Medication; Tamoxifen; Triptorelin Pamoate

2010
Predictors of non-adherence to aromatase inhibitors among commercially insured women with breast cancer.
    Breast cancer research and treatment, 2011, Volume: 125, Issue:1

    Topics: Adult; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Databases as Topic; Delivery of Health Care; Drug Costs; Female; Health Knowledge, Attitudes, Practice; Humans; Insurance, Health; Letrozole; Logistic Models; Medication Adherence; Middle Aged; Nitriles; Odds Ratio; Postmenopause; Retrospective Studies; Risk Assessment; Risk Factors; Treatment Outcome; Triazoles; United States

2011
Inflammatory cytokines and aromatase inhibitor-associated musculoskeletal syndrome: a case-control study.
    British journal of cancer, 2010, Jul-27, Volume: 103, Issue:3

    Topics: Aged; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Bridged-Ring Compounds; Case-Control Studies; Cytokines; Estrogens; Female; Humans; Inflammation; Middle Aged; Musculoskeletal Diseases; Postmenopause; Syndrome; Tamoxifen; Taxoids

2010
Rheumatoid arthritis and aromatase inhibitors.
    Joint bone spine, 2011, Volume: 78, Issue:1

    Topics: Adenocarcinoma; Aged; Anastrozole; Androstadienes; Aromatase Inhibitors; Arthritis, Rheumatoid; Breast Neoplasms; Carcinoma, Ductal; Combined Modality Therapy; Female; Humans; Letrozole; Middle Aged; Nitriles; Triazoles

2011
Cognitive changes associated with endocrine therapy for breast cancer.
    Maturitas, 2010, Volume: 67, Issue:3

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Case-Control Studies; Chemotherapy, Adjuvant; Cognition; Cognition Disorders; Female; Humans; Letrozole; Memory; Neoplasms, Hormone-Dependent; Nitriles; Prospective Studies; Randomized Controlled Trials as Topic; Selective Estrogen Receptor Modulators; Tamoxifen; Triazoles; United States; Women's Health

2010
Suppression of ovarian function in combination with an aromatase inhibitor as treatment for advanced breast cancer in pre-menopausal women.
    European journal of cancer (Oxford, England : 1990), 2010, Volume: 46, Issue:16

    Topics: Adult; Anastrozole; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Female; Gonadotropin-Releasing Hormone; Goserelin; Hormones; Humans; Middle Aged; Nitriles; Ovary; Premenopause; Tamoxifen; Triazoles

2010
Genome-wide associations and functional genomic studies of musculoskeletal adverse events in women receiving aromatase inhibitors.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Nov-01, Volume: 28, Issue:31

    Topics: Aged; Aged, 80 and over; Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Case-Control Studies; Chromosome Mapping; Chromosomes, Human, Pair 14; Clinical Trials, Phase III as Topic; Estrogens; Female; Gene Expression Regulation, Neoplastic; Genome-Wide Association Study; Genotype; Humans; Logistic Models; Middle Aged; Musculoskeletal System; Neoplasm Staging; Nitriles; Polymorphism, Single Nucleotide; Postmenopause; Proto-Oncogene Proteins; Randomized Controlled Trials as Topic; Receptors, Interleukin-17; Retrospective Studies; Severity of Illness Index; Triazoles

2010
Down-regulation of heat-shock protein 70 (HSP-70) correlated with responsiveness to neoadjuvant aromatase inhibitor therapy in breast cancer patients.
    Anticancer research, 2010, Volume: 30, Issue:9

    Topics: Aged; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Down-Regulation; Drug Resistance, Neoplasm; Female; HSP70 Heat-Shock Proteins; Humans; Immunohistochemistry; Ki-67 Antigen; Letrozole; Neoadjuvant Therapy; Nitriles; Randomized Controlled Trials as Topic; Triazoles

2010
Expression of estrogen receptor beta and phosphorylation of estrogen receptor alpha serine 167 correlate with progression-free survival in patients with metastatic breast cancer treated with aromatase inhibitors.
    Oncology, 2010, Volume: 79, Issue:1-2

    Topics: Adult; Aged; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Disease-Free Survival; Estrogen Receptor alpha; Estrogen Receptor beta; Fadrozole; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Middle Aged; Nitriles; Phosphorylation; Predictive Value of Tests; Prognosis; Retrospective Studies; Serine; Tamoxifen; Triazoles

2010
[A successful case of the super elderly breast cancer patient treated with exemestane].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:12

    Topics: Adenocarcinoma; Aged, 80 and over; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Female; Humans

2010
Ki67 index changes, pathological response and clinical benefits in primary breast cancer patients treated with 24 weeks of aromatase inhibition.
    Cancer science, 2011, Volume: 102, Issue:4

    Topics: Aged; Androstadienes; Aromatase; Aromatase Inhibitors; Biomarkers, Tumor; Breast Neoplasms; Female; Humans; Ki-67 Antigen; Lymphatic Metastasis; Mastectomy, Segmental; Middle Aged; Neoplasm Staging; Postmenopause; Receptors, Estrogen; Receptors, Progesterone; Survival Rate; Treatment Outcome

2011
Time to TEAM: exemestane, or tamoxifen then exemestane?
    Lancet (London, England), 2011, Jan-22, Volume: 377, Issue:9762

    Topics: Adenocarcinoma; Androstadienes; Antineoplastic Agents, Hormonal; Breast Neoplasms; Disease-Free Survival; Female; Humans; Postmenopause; Randomized Controlled Trials as Topic; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Translational Research, Biomedical

2011
Aromatase inhibitor-induced loss of grip strength is body mass index dependent: hypothesis-generating findings for its pathogenesis.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2011, Volume: 22, Issue:8

    Topics: Aged; Anastrozole; Androstadienes; Aromatase Inhibitors; Arthralgia; Body Mass Index; Breast Neoplasms; Cohort Studies; Female; Hand Strength; Humans; Letrozole; Middle Aged; Musculoskeletal Diseases; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Syndrome; Tamoxifen; Triazoles

2011
Aromatase inhibitor exemestane has antiproliferative effects on human mesothelioma cells.
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2011, Volume: 6, Issue:3

    Topics: Androstadienes; Aromatase; Aromatase Inhibitors; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Proliferation; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Follow-Up Studies; Humans; Immunoenzyme Techniques; Mesothelioma; Prognosis; Receptors, Estrogen; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Survival Rate; Tumor Cells, Cultured

2011
Self-reported cognitive functioning in postmenopausal breast cancer patients before and during endocrine treatment: findings from the neuropsychological TEAM side-study.
    Psycho-oncology, 2012, Volume: 21, Issue:5

    Topics: Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Anxiety; Breast Neoplasms; Case-Control Studies; Chemotherapy, Adjuvant; Cognition; Cognition Disorders; Depression; Female; Humans; Middle Aged; Neuropsychological Tests; Postmenopause; Prospective Studies; Randomized Controlled Trials as Topic; Self Report; Surveys and Questionnaires; Tamoxifen

2012
Binding features of steroidal and nonsteroidal inhibitors.
    Steroids, 2011, Volume: 76, Issue:8

    Topics: Amino Acids; Androgens; Androstadienes; Androstenedione; Aromatase; Aromatase Inhibitors; Binding Sites; Breast Neoplasms; Catalytic Domain; Estrogens; Estrone; Female; Humans; Letrozole; Mutagenesis, Site-Directed; NADPH-Ferrihemoprotein Reductase; Neoplasms, Hormone-Dependent; Nitriles; Protein Conformation; Structure-Activity Relationship; Triazoles

2011
Examination of the use of Exemestane in patients with metastatic breast cancer.
    Breast cancer (Tokyo, Japan), 2011, Volume: 18, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Liver Neoplasms; Lung Neoplasms; Medroxyprogesterone Acetate; Middle Aged; Retrospective Studies; Tamoxifen

2011
"MAPping" the course of chemoprevention in breast cancer.
    The New England journal of medicine, 2011, Jun-23, Volume: 364, Issue:25

    Topics: Androstadienes; Aromatase Inhibitors; Biomarkers; Breast Neoplasms; Female; Humans; Risk Assessment

2011
Estrogen and progesterone receptors in breast cancer.
    Clinical advances in hematology & oncology : H&O, 2011, Volume: 9, Issue:5

    Topics: Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Cell Proliferation; Female; Humans; Receptors, Estrogen; Receptors, Progesterone; Selective Estrogen Receptor Modulators; Signal Transduction; Tamoxifen

2011
Heterogeneous HER2 gene amplification: impact on patient outcome and a clinically relevant definition.
    American journal of clinical pathology, 2011, Volume: 136, Issue:2

    Topics: Androstadienes; Antineoplastic Agents; Breast Neoplasms; Cohort Studies; Female; Gene Amplification; Genes, erbB-2; Humans; Immunohistochemistry; In Situ Hybridization, Fluorescence; Multicenter Studies as Topic; Practice Guidelines as Topic; Prognosis; Tamoxifen; Treatment Outcome

2011
Relationship between body mass index and preoperative treatment response to aromatase inhibitor exemestane in postmenopausal patients with primary breast cancer.
    Breast (Edinburgh, Scotland), 2012, Volume: 21, Issue:1

    Topics: Aged; Androstadienes; Aromatase Inhibitors; Body Mass Index; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Middle Aged; Neoadjuvant Therapy; Postmenopause; Preoperative Care; Treatment Outcome

2012
Exemestane for breast-cancer prevention.
    The New England journal of medicine, 2011, 09-15, Volume: 365, Issue:11

    Topics: Androstadienes; Aromatase Inhibitors; Bone Density; Breast Neoplasms; Drug Monitoring; Female; Humans; Postmenopause

2011
Exemestane for breast-cancer prevention.
    The New England journal of medicine, 2011, 09-15, Volume: 365, Issue:11

    Topics: Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Estrogen Replacement Therapy; Female; Humans; Postmenopause

2011
Exemestane for breast-cancer prevention.
    The New England journal of medicine, 2011, 09-15, Volume: 365, Issue:11

    Topics: Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Female; Genes, BRCA1; Genes, BRCA2; Humans; Mutation; Patient Selection; Postmenopause

2011
Is primary endocrine therapy effective in treating the elderly, unfit patient with breast cancer?
    Annals of the Royal College of Surgeons of England, 2011, Volume: 93, Issue:4

    Topics: Aged; Aged, 80 and over; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Breast Neoplasms; Disease Progression; Female; Humans; Letrozole; Middle Aged; Nitriles; Receptors, Estrogen; Retrospective Studies; Survival Analysis; Tamoxifen; Treatment Outcome; Triazoles

2011
Could trastuzumab suppress hepatitis C virus in a patient with chronic hepatitis and breast cancer?
    The American journal of gastroenterology, 2011, Volume: 106, Issue:10

    Topics: Aged; Androstadienes; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Biomarkers; Biomarkers, Tumor; Breast Neoplasms; Drug Combinations; ErbB Receptors; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Neoplasm Staging; Oxonic Acid; Receptor, ErbB-2; Receptors, Estrogen; Tegafur; Trastuzumab

2011
The breast cancer chemoprevention debate.
    Journal of the National Cancer Institute, 2011, Nov-16, Volume: 103, Issue:22

    Topics: Anastrozole; Androstadienes; Anticarcinogenic Agents; Aromatase Inhibitors; Breast Neoplasms; Chemoprevention; Clinical Trials as Topic; Female; Humans; Models, Statistical; Nitriles; Raloxifene Hydrochloride; Risk Assessment; Risk Factors; Selective Estrogen Receptor Modulators; Tamoxifen; Triazoles

2011
Hormone treatment without surgery for patients aged 75 years or older with operable breast cancer.
    Annals of surgical oncology, 2012, Volume: 19, Issue:4

    Topics: Aged; Aged, 80 and over; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Disease Progression; Female; Follow-Up Studies; Humans; Letrozole; Nitriles; Receptor, ErbB-2; Survival Rate; Tamoxifen; Treatment Outcome; Triazoles

2012
[Chemoprevention of breast cancer: exemestane ready to be tested in study setting].
    Nederlands tijdschrift voor geneeskunde, 2012, Volume: 156, Issue:1

    Topics: Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Chemoprevention; Cost-Benefit Analysis; Female; Humans; Incidence; Neoplasm Invasiveness; Postmenopause; Risk Factors

2012
Aromatase inhibitors and musculoskeletal adverse events.
    The Lancet. Oncology, 2012, Volume: 13, Issue:4

    Topics: Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Carpal Tunnel Syndrome; Female; Humans; Musculoskeletal Abnormalities; Tamoxifen

2012
Deep time: the long and the short of adjuvant endocrine therapy for breast cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Mar-01, Volume: 30, Issue:7

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Letrozole; Nitriles; Tamoxifen; Triazoles

2012
Incidence and management of arthralgias in breast cancer patients treated with aromatase inhibitors in an outpatient oncology clinic.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2012, Volume: 18, Issue:4

    Topics: Anastrozole; Androstadienes; Aromatase Inhibitors; Arthralgia; Breast Neoplasms; Female; Humans; Incidence; Neoplasms, Hormone-Dependent; Nitriles; Outpatients; Retrospective Studies; Triazoles

2012
Bone loss associated with prevention of breast cancer.
    The Lancet. Oncology, 2012, Volume: 13, Issue:3

    Topics: Androstadienes; Anticarcinogenic Agents; Aromatase Inhibitors; Bone and Bones; Bone Density; Breast Neoplasms; Female; Humans; Osteoporosis; Postmenopause; Primary Prevention

2012
Association between age at diagnosis and disease-specific mortality among postmenopausal women with hormone receptor-positive breast cancer.
    JAMA, 2012, Feb-08, Volume: 307, Issue:6

    Topics: Adult; Age of Onset; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cause of Death; Female; Follow-Up Studies; Humans; Middle Aged; Postmenopause; Prognosis; Randomized Controlled Trials as Topic; Receptors, Estrogen; Receptors, Progesterone; Risk; Tamoxifen

2012
What is new in primary care? Best articles from the past year.
    Obstetrics and gynecology, 2012, Volume: 119, Issue:4

    Topics: Alzheimer Disease; Androstadienes; Aromatase Inhibitors; Bone Density Conservation Agents; Breast Neoplasms; Contraception; Dementia, Vascular; Diphosphonates; Estrogens, Conjugated (USP); Female; Femoral Fractures; Humans; Mass Screening; Ovarian Neoplasms; Pregnancy; Pregnancy in Diabetics; Primary Health Care; Randomized Controlled Trials as Topic; Smoking; Stroke

2012
Efficacy of exemestane after nonsteroidal aromatase inhibitor use in metastatic breast cancer patients.
    Asian Pacific journal of cancer prevention : APJCP, 2012, Volume: 13, Issue:3

    Topics: Adult; Aged; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Disease-Free Survival; Female; Humans; Middle Aged; Neoplasm Metastasis; Retrospective Studies

2012
BOLERO-2 - will this change practice in advanced breast cancer?
    Breast cancer research : BCR, 2012, Jun-19, Volume: 14, Issue:3

    Topics: Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Everolimus; Female; Humans; Immunosuppressive Agents; Sirolimus; TOR Serine-Threonine Kinases

2012
Whole-genome analysis informs breast cancer response to aromatase inhibition.
    Nature, 2012, Jun-10, Volume: 486, Issue:7403

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Breast Neoplasms; DNA Repair; Exome; Exons; Female; Genetic Variation; Genome, Human; Humans; Letrozole; MAP Kinase Kinase 4; MAP Kinase Kinase Kinase 1; Mutation; Nitriles; Receptors, Estrogen; Treatment Outcome; Triazoles

2012
Effect of aromatase inhibitors on background parenchymal enhancement and amount of fibroglandular tissue at breast MR imaging.
    Radiology, 2012, Volume: 264, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Contrast Media; Female; Gadolinium DTPA; Humans; Image Enhancement; Image Interpretation, Computer-Assisted; Letrozole; Magnetic Resonance Imaging; Middle Aged; Neoplasm Staging; Nitriles; Postmenopause; Retrospective Studies; Subtraction Technique; Triazoles

2012
Exemestane for primary prevention of breast cancer in postmenopausal women.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2012, Aug-15, Volume: 69, Issue:16

    Topics: Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemoprevention; Estrogen Antagonists; Female; Genetic Predisposition to Disease; Humans; Middle Aged; Postmenopause; Primary Prevention; Raloxifene Hydrochloride; Risk Assessment; Selective Estrogen Receptor Modulators; Tamoxifen

2012
Relationship between specific adverse events and efficacy of exemestane therapy in early postmenopausal breast cancer patients.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2012, Volume: 23, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Humans; Middle Aged; Neoplasm Recurrence, Local; Postmenopause; Treatment Outcome

2012
Apoptosis and autophagy in breast cancer cells following exemestane treatment.
    PloS one, 2012, Volume: 7, Issue:8

    Topics: Androstadienes; Antineoplastic Agents; Apoptosis; Aromatase; Autophagy; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Gene Expression Regulation, Neoplastic; Humans; Receptors, Estrogen

2012
Dry eye syndrome in aromatase inhibitor users.
    Clinical & experimental ophthalmology, 2013, Volume: 41, Issue:3

    Topics: Aged; Aged, 80 and over; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Blepharitis; Breast Neoplasms; Conjunctival Diseases; Dry Eye Syndromes; Female; Humans; Keratitis; Letrozole; Middle Aged; Nitriles; Ovarian Neoplasms; Retrospective Studies; Triazoles; Vision Disorders

2013
Prognostic/Predictive immunohistochemistry assays for estrogen receptor-positive breast cancer: back to the future?
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Dec-20, Volume: 30, Issue:36

    Topics: Androstadienes; Breast Neoplasms; Female; Humans; Neoplasms, Hormone-Dependent; Tamoxifen; Tissue Array Analysis

2012
Incidence and predictors of ovarian function recovery (OFR) in breast cancer (BC) patients with chemotherapy-induced amenorrhea (CIA) who switched from tamoxifen to exemestane.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2013, Volume: 24, Issue:3

    Topics: Adult; Amenorrhea; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Disease-Free Survival; Drug Substitution; Estradiol; Female; Humans; Incidence; Kaplan-Meier Estimate; Menstruation; Middle Aged; Ovary; Prospective Studies; Recovery of Function; ROC Curve; Tamoxifen; Treatment Outcome

2013
The role of chemoprevention in modifying the risk of breast cancer in women with atypical breast lesions.
    Breast cancer research and treatment, 2012, Volume: 136, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Anticarcinogenic Agents; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Chemoprevention; Female; Humans; Hyperplasia; Mammary Glands, Human; Middle Aged; Precancerous Conditions; Raloxifene Hydrochloride; Tamoxifen

2012
Inhibition of the proliferation of acquired aromatase inhibitor-resistant breast cancer cells by histone deacetylase inhibitor LBH589 (panobinostat).
    Breast cancer research and treatment, 2013, Volume: 137, Issue:1

    Topics: Aged; Androstadienes; Animals; Antineoplastic Agents; Apoptosis; Aromatase Inhibitors; Breast Neoplasms; Cell Cycle Checkpoints; Cell Proliferation; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Gene Expression; Gene Knockdown Techniques; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Indoles; Letrozole; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; NF-kappa B p50 Subunit; Nitriles; Panobinostat; Triazoles; Tumor Burden; Xenograft Model Antitumor Assays

2013
Changes of tumor infiltrating lymphocyte subtypes before and after neoadjuvant endocrine therapy in estrogen receptor-positive breast cancer patients--an immunohistochemical study of Cd8+ and Foxp3+ using double immunostaining with correlation to the path
    The International journal of biological markers, 2012, Dec-27, Volume: 27, Issue:4

    Topics: Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Biomarkers, Tumor; Breast Neoplasms; CD8-Positive T-Lymphocytes; Clinical Trials as Topic; Female; Forkhead Transcription Factors; Humans; Immunohistochemistry; Lymphocyte Subsets; Lymphocytes, Tumor-Infiltrating; Neoadjuvant Therapy; Receptors, Estrogen; T-Lymphocytes, Regulatory

2012
Synergistic effects of exemestane and aspirin on MCF-7 human breast cancer cells.
    Asian Pacific journal of cancer prevention : APJCP, 2012, Volume: 13, Issue:11

    Topics: Androstadienes; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Aspirin; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Proliferation; Dinoprostone; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Female; Flow Cytometry; Humans; Tumor Cells, Cultured

2012
What is the optimal endocrine therapy for postmenopausal women with hormone receptor-positive early breast cancer?
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Apr-10, Volume: 31, Issue:11

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Letrozole; Middle Aged; Nitriles; Postmenopause; Practice Guidelines as Topic; Receptors, Estrogen; Tamoxifen; Time Factors; Triazoles

2013
Current role of endocrine therapy in the management of breast cancer.
    Breast cancer (Tokyo, Japan), 2002, Volume: 9, Issue:4

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Estrogen Receptor Modulators; Female; Humans; Letrozole; Nitriles; Tamoxifen; Triazoles

2002
Could exemestane affect insulin-like growth factors, interleukin 6 and bone metabolism in postmenopausal advanced breast cancer patients after failure on aminoglutethimide, anastrozole or letrozole?
    International journal of oncology, 2003, Volume: 22, Issue:5

    Topics: Aged; Androstadienes; Antineoplastic Agents; Body Mass Index; Bone and Bones; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; Insulin-Like Growth Factor Binding Proteins; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Interleukin-6; Lymphatic Metastasis; Middle Aged; Neoplasm Metastasis; Postmenopause; Receptors, Estrogen; Receptors, Progesterone; Tissue Distribution; Treatment Failure

2003
Economic evaluation of antiaromatase agents in the second-line treatment of metastatic breast cancer.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2003, Volume: 11, Issue:11

    Topics: Aged; Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Canada; Clinical Trials, Phase III as Topic; Cost-Benefit Analysis; Enzyme Inhibitors; Female; Humans; Letrozole; Megestrol; Middle Aged; Nitriles; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Survival Analysis; Triazoles

2003
[Clinical trial on exemestane in the treatment of postmenopausal women with advanced breast cancer].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2003, Volume: 25, Issue:5

    Topics: Adult; Aged; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; Middle Aged; Postmenopause

2003
Sequencing of endocrine therapy in postmenopausal women with advanced breast cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Jan-01, Volume: 10, Issue:1 Pt 2

    Topics: Androstadienes; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Disease Progression; Female; Humans; Neoplasm Metastasis; Neoplasms, Hormone-Dependent; Postmenopause; Receptors, Estrogen; Tamoxifen

2004
Metastatic breast cancer response after Exemestane withdrawal: a case report.
    Breast (Edinburgh, Scotland), 2004, Volume: 13, Issue:1

    Topics: Adult; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Carcinoma, Ductal, Breast; Enzyme Inhibitors; Female; Humans; Neoplasm Recurrence, Local; Remission, Spontaneous

2004
New stars in the sky of treatment for early breast cancer.
    The New England journal of medicine, 2004, Mar-11, Volume: 350, Issue:11

    Topics: Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Estrogen Antagonists; Female; Humans; Neoplasms, Hormone-Dependent; Postmenopause; Tamoxifen

2004
Changes in vascular endothelial growth factor (VEGF) after chemoendocrine therapy in breast cancer.
    European journal of gynaecological oncology, 2004, Volume: 25, Issue:1

    Topics: Androstadienes; Angiopoietin-1; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; DNA Primers; Docetaxel; Dose-Response Relationship, Drug; Doxorubicin; Female; Gene Expression Regulation, Neoplastic; Humans; Letrozole; Neovascularization, Pathologic; Nitriles; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Tamoxifen; Taxoids; Triazoles; Vascular Endothelial Growth Factor A

2004
Effects of a combination of exemestane and paclitaxel on human tumor cells in vitro.
    Anti-cancer drugs, 2004, Volume: 15, Issue:1

    Topics: Androstadienes; Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Cell Line, Tumor; Drug Screening Assays, Antitumor; Drug Therapy, Combination; Endometrial Neoplasms; Enzyme Inhibitors; Female; Humans; Ovarian Neoplasms; Paclitaxel; Receptors, Estrogen; Reverse Transcriptase Polymerase Chain Reaction

2004
Tamoxifen shuffle.
    Health news (Waltham, Mass.), 2004, Volume: 10, Issue:5

    Topics: Androstadienes; Antineoplastic Agents; Breast Neoplasms; Female; Follow-Up Studies; Humans; Middle Aged; Neoplasm Recurrence, Local; Tamoxifen

2004
Adjuvant treatment of breast cancer with exemestane.
    The New England journal of medicine, 2004, Jul-01, Volume: 351, Issue:1

    Topics: Androstadienes; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Mastectomy; Radiotherapy, Adjuvant; Tamoxifen

2004
Adjuvant treatment of breast cancer with exemestane.
    The New England journal of medicine, 2004, Jul-01, Volume: 351, Issue:1

    Topics: Androstadienes; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chemotherapy, Adjuvant; Data Interpretation, Statistical; Female; Humans; Tamoxifen

2004
Adjuvant treatment of breast cancer with exemestane.
    The New England journal of medicine, 2004, Jul-01, Volume: 351, Issue:1

    Topics: Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Bone Density; Bone Resorption; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Fractures, Bone; Humans; Osteoporosis; Tamoxifen

2004
Exemestane following tamoxifen in postmenopausal women with primary breast cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004, Sep-15, Volume: 22, Issue:18

    Topics: Androstadienes; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Bone Density; Bone Resorption; Breast Neoplasms; Clinical Trials as Topic; Drug Administration Schedule; Enzyme Inhibitors; Female; Humans; Risk Factors; Tamoxifen

2004
[A case of aged advanced breast cancer with multiple lung and pleural metastases responding to exemestane monotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:10

    Topics: Aged; Androstadienes; Antineoplastic Agents; Biomarkers, Tumor; Breast Neoplasms; Carcinoembryonic Antigen; Carcinoma, Ductal, Breast; Female; Humans; Lung Neoplasms; Mucin-1; Pleural Neoplasms

2004
Effects of exemestane and tamoxifen in a postmenopausal breast cancer model.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Nov-01, Volume: 10, Issue:21

    Topics: Androstadienes; Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Disease Progression; Dose-Response Relationship, Drug; Female; Humans; Letrozole; Mammary Neoplasms, Animal; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Random Allocation; Tamoxifen; Time Factors; Triazoles

2004
[Anastrozole-resistant breast cancer responsive to exemestane--a case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:12

    Topics: Aged; Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Carcinoma, Ductal, Breast; Drug Resistance, Neoplasm; Female; Humans; Nitriles; Postmenopause; Triazoles

2004
[A patient with metastatic breast cancer associated with retention of pleural effusion with no response to both CMF and exemestane, whose life was saved by high-dose toremifene].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:2

    Topics: Aged; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Humans; Lymph Nodes; Lymphatic Metastasis; Methotrexate; Pleural Effusion; Remission Induction; Salvage Therapy; Toremifene

2005
[New results of endocrine therapy of breast cancer (the role of Aromasin)].
    Voprosy onkologii, 2004, Volume: 50, Issue:6

    Topics: Androstadienes; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Tamoxifen; Treatment Outcome

2004
[Effective reduction of elevated tumor markers by exemestane--a 12-year follow-up of a case of bone metastatic breast cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:3

    Topics: Aged; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bone Neoplasms; Breast Neoplasms; Carcinoembryonic Antigen; Drug Administration Schedule; Female; Floxuridine; Humans; Medroxyprogesterone Acetate; Mucin-1; Radionuclide Imaging

2005
[New strategies against breast carcinoma. To outwit the resistance tendency of tumor cells].
    MMW Fortschritte der Medizin, 2005, Mar-10, Volume: 147, Issue:10

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Drug Resistance, Neoplasm; Estradiol; Female; Fulvestrant; Humans; Multicenter Studies as Topic; Neoplasm Recurrence, Local; Nitriles; Tamoxifen; Time Factors; Triazoles

2005
Safety of exemestane in the Intergroup Exemestane Study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, May-01, Volume: 23, Issue:13

    Topics: Androstadienes; Aromatase Inhibitors; Bone Resorption; Breast Neoplasms; Clinical Trials as Topic; Female; Humans; Research Design; Time Factors

2005
Aromatase inhibitors and bone loss: risks in perspective.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Aug-01, Volume: 23, Issue:22

    Topics: Androstadienes; Aromatase Inhibitors; Bone Resorption; Breast Neoplasms; Humans; Randomized Controlled Trials as Topic; Risk Factors

2005
Aromatase inhibitors: cellular and molecular effects.
    The Journal of steroid biochemistry and molecular biology, 2005, Volume: 95, Issue:1-5

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Cell Proliferation; Drug Resistance, Neoplasm; Female; Gene Expression; Humans; Ki-67 Antigen; Letrozole; Neoadjuvant Therapy; Nitriles; Oligonucleotide Array Sequence Analysis; Receptors, Progesterone; Tamoxifen; Triazoles

2005
Durable clinical benefit with exemestane in leptomeningeal metastasis of breast cancer.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2005, Volume: 7, Issue:8

    Topics: Adult; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Female; Humans; Meningeal Neoplasms; Time Factors

2005
[Aromatase inhibitors in the treatment of breast cancer: current status and some problems].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2005, Volume: 27, Issue:8

    Topics: Adult; Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Letrozole; Middle Aged; Nitriles; Triazoles

2005
Exemestane in metastatic breast cancer: effective therapy after third-generation non-steroidal aromatase inhibitor failure.
    Breast (Edinburgh, Scotland), 2006, Volume: 15, Issue:3

    Topics: Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Disease Progression; Female; Humans; Male; Receptors, Estrogen; Retrospective Studies; Treatment Failure

2006
Can exemestane improve adjuvant treatment for postmenopausal women with primary breast cancer?
    Nature clinical practice. Oncology, 2004, Volume: 1, Issue:1

    Topics: Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Disease-Free Survival; Female; Humans; Neoplasms, Hormone-Dependent; Postmenopause; Receptors, Estrogen; Tamoxifen

2004
Bone loss with exemestane: Is the jury still out?
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-20, Volume: 23, Issue:36

    Topics: Androstadienes; Antineoplastic Agents; Bone Density; Breast Neoplasms; Female; Femur; Humans; Postmenopause; Reproducibility of Results

2005
Sequential treatment with exemestane and non-steroidal aromatase inhibitors in advanced breast cancer.
    Oncology, 2005, Volume: 69, Issue:6

    Topics: Aged; Aged, 80 and over; Anastrozole; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Confidence Intervals; Disease Progression; Drug Administration Schedule; Female; Humans; Letrozole; Lymphatic Metastasis; Middle Aged; Neoplasm Staging; Nitriles; Postmenopause; Treatment Outcome; Triazoles

2005
[Advance and current status of exemestane and androstadienes in the treatment of breast cancer].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2005, Volume: 27, Issue:12

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Drug Administration Schedule; Female; Humans; Nitriles; Postmenopause; Triazoles

2005
Quality of life in the intergroup exemestane study: a randomized trial of exemestane versus continued tamoxifen after 2 to 3 years of tamoxifen in postmenopausal women with primary breast cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Feb-20, Volume: 24, Issue:6

    Topics: Adult; Aged; Androstadienes; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Female; Follow-Up Studies; Humans; Middle Aged; Patient Satisfaction; Postmenopause; Quality of Life; Randomized Controlled Trials as Topic; Tamoxifen; Time Factors; Treatment Outcome

2006
Changing the gold standard in adjuvant therapy for breast cancer:from tamoxifen to aromatase inhibition.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2005, Volume: 59 Suppl 2

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Enzyme Inhibitors; Female; Humans; Letrozole; Nitriles; Tamoxifen; Triazoles

2005
A 62-year-old woman with a new diagnosis of breast cancer.
    JAMA, 2006, Mar-22, Volume: 295, Issue:12

    Topics: Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Carcinoma, Lobular; Chemotherapy, Adjuvant; Combined Modality Therapy; Decision Making; Female; Humans; Mastectomy, Segmental; Middle Aged; Prognosis; Selective Estrogen Receptor Modulators; Tamoxifen

2006
Does survival increase in metastatic breast cancer with recently available anticancer drugs?
    Oncology research, 2006, Volume: 15, Issue:9

    Topics: Aged; Anastrozole; Androstadienes; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Breast Neoplasms; Female; Humans; Letrozole; Middle Aged; Neoplasm Metastasis; Nitriles; Retrospective Studies; Survival Analysis; Tamoxifen; Triazoles

2006
Identification of the aromatase inhibitors anastrozole and exemestane in human urine using liquid chromatography/tandem mass spectrometry.
    Rapid communications in mass spectrometry : RCM, 2006, Volume: 20, Issue:12

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chromatography, High Pressure Liquid; Female; Humans; Male; Nitriles; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection; Tandem Mass Spectrometry; Triazoles

2006
Adjuvant aromatase inhibitors for early breast cancer after chemotherapy-induced amenorrhoea: caution and suggested guidelines.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Jun-01, Volume: 24, Issue:16

    Topics: Adult; Amenorrhea; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Estrogen Receptor Modulators; Female; Follicle Stimulating Hormone; Humans; Letrozole; Luteinizing Hormone; Middle Aged; Neoplasm Staging; Nitriles; Ovariectomy; Practice Guidelines as Topic; Tamoxifen; Triazoles

2006
Pharmacoeconomic analysis of adjuvant therapy with exemestane, anastrozole, letrozole or tamoxifen in postmenopausal women with operable and estrogen receptor-positive breast cancer.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2006, Volume: 8, Issue:5

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Cohort Studies; Computer Simulation; Cost-Benefit Analysis; Estrogen Antagonists; Estrogens; Fees, Pharmaceutical; Female; Follow-Up Studies; Humans; Letrozole; Markov Chains; Middle Aged; Models, Theoretical; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Receptors, Estrogen; Tamoxifen; Triazoles

2006
Management of choroidal metastases from breast carcinomas using aromatase inhibitors.
    Current opinion in ophthalmology, 2006, Volume: 17, Issue:3

    Topics: Aged; Aged, 80 and over; Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Choroid Neoplasms; Combined Modality Therapy; Female; Humans; Letrozole; Mastectomy, Radical; Mastectomy, Segmental; Mastectomy, Simple; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Tamoxifen; Treatment Outcome; Triazoles

2006
Can switching treatments improve breast-cancer outcome?
    The Lancet. Oncology, 2006, Volume: 7, Issue:7

    Topics: Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Middle Aged; Postmenopause; Tamoxifen

2006
Cost-utility of adjuvant hormone therapies for breast cancer in post-menopausal women: sequential tamoxifen-exemestane and upfront anastrozole.
    Breast cancer research and treatment, 2007, Volume: 101, Issue:3

    Topics: Aged; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Cost-Benefit Analysis; Disease-Free Survival; Drug Administration Schedule; Drug Costs; Female; Humans; Markov Chains; Middle Aged; Models, Economic; Neoplasm Recurrence, Local; Nitriles; Postmenopause; Quality-Adjusted Life Years; Tamoxifen; Treatment Outcome; Triazoles; United States

2007
Debilitating musculoskeletal pain and stiffness with letrozole and exemestane: associated tenosynovial changes on magnetic resonance imaging.
    Breast cancer research and treatment, 2007, Volume: 104, Issue:1

    Topics: Aged; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Carpal Tunnel Syndrome; Female; Humans; Letrozole; Magnetic Resonance Imaging; Middle Aged; Musculoskeletal Diseases; Nitriles; Pain; Severity of Illness Index; Triazoles; Ultrasonography; Wrist Joint

2007
Cost-utility of adjuvant hormone therapies with aromatase inhibitors in post-menopausal women with breast cancer: upfront anastrozole, sequential tamoxifen-exemestane and extended tamoxifen-letrozole.
    Breast (Edinburgh, Scotland), 2007, Volume: 16, Issue:3

    Topics: Aged; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Belgium; Breast Neoplasms; Canada; Chemotherapy, Adjuvant; Cost-Benefit Analysis; Drug Costs; Female; Humans; Letrozole; Markov Chains; Middle Aged; Nitriles; Postmenopause; Proportional Hazards Models; Quality-Adjusted Life Years; Tamoxifen; Triazoles

2007
[A patient with advanced breast cancer refractory to chemotherapy accompanied by carcinomatous pleurisy and multiple bone metastasis that responded to combination therapy with high-dose toremifene and docetaxel].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:1

    Topics: Aged; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Carcinoma, Ductal, Breast; Cyclophosphamide; Docetaxel; Drug Administration Schedule; Epirubicin; Female; Fluorouracil; Humans; Paclitaxel; Pleural Effusion, Malignant; Pleural Neoplasms; Quality of Life; Remission Induction; Taxoids; Toremifene

2007
[Locally advanced breast cancer with a good response to sequential endocrine monotherapy--a case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:1

    Topics: Aged, 80 and over; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinoma, Ductal, Breast; Drug Administration Schedule; Female; Humans; Nitriles; Remission Induction; Tamoxifen; Triazoles

2007
Re: Survival with aromatase inhibitors and inactivators versus standard hormonal therapy in advanced breast cancer: meta-analysis.
    Journal of the National Cancer Institute, 2007, Jan-17, Volume: 99, Issue:2

    Topics: Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Meta-Analysis as Topic; Neoplasms, Hormone-Dependent; Randomized Controlled Trials as Topic; Research Design; Survival Analysis

2007
Optimising bone health in survivors of breast cancer.
    The Lancet. Oncology, 2007, Volume: 8, Issue:2

    Topics: Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Bone Density; Bone Neoplasms; Bone Remodeling; Breast Neoplasms; Female; Humans; Postmenopause; Survivors; Tamoxifen

2007
Cancer: some reasons to be hopeful.
    Lancet (London, England), 2007, Feb-17, Volume: 369, Issue:9561

    Topics: Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Disease-Free Survival; Drug Administration Schedule; Female; Humans; Neoplasm Recurrence, Local; Tamoxifen

2007
Switching to aromatase inhibitors in early breast cancer.
    Lancet (London, England), 2007, Feb-17, Volume: 369, Issue:9561

    Topics: Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Drug Administration Schedule; Female; Humans; Randomized Controlled Trials as Topic; Survival Rate; Tamoxifen

2007
Exemestane after non-steroidal aromatase inhibitors for post-menopausal women with advanced breast cancer.
    Breast (Edinburgh, Scotland), 2007, Volume: 16, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Bone Neoplasms; Breast Neoplasms; Female; Follow-Up Studies; Humans; Liver Neoplasms; Lung Neoplasms; Middle Aged; Postmenopause; Retrospective Studies; Soft Tissue Neoplasms

2007
[Clinical study of aromatase inhibitors in advanced breast cancer].
    Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2007, Apr-18, Volume: 39, Issue:2

    Topics: Adult; Aged; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Carcinoma, Ductal, Breast; Female; Humans; Middle Aged; Nitriles; Postmenopause; Treatment Outcome; Triazoles

2007
Patients' knowledge and experience of adjuvant endocrine therapy for early breast cancer: a European study.
    Breast (Edinburgh, Scotland), 2007, Volume: 16, Issue:5

    Topics: Aged; Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Communication Barriers; Decision Making; Europe; Female; Health Knowledge, Attitudes, Practice; Humans; Letrozole; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Selective Estrogen Receptor Modulators; Surveys and Questionnaires; Tamoxifen; Triazoles

2007
Clinical evaluation of the use of exemestane as further hormonal therapy after nonsteroidal aromatase inhibitors in postmenopausal metastatic breast cancer patients.
    Cancer investigation, 2007, Volume: 25, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Letrozole; Middle Aged; Nitriles; Postmenopause; Treatment Outcome; Triazoles

2007
Exemestane or tamoxifen?
    Lancet (London, England), 2007, May-12, Volume: 369, Issue:9573

    Topics: Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Bone Density; Breast Neoplasms; Drug Administration Schedule; Female; Humans; Postmenopause; Tamoxifen

2007
Exemestane or tamoxifen?
    Lancet (London, England), 2007, May-12, Volume: 369, Issue:9573

    Topics: Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Survival Analysis; Tamoxifen

2007
Cost-effectiveness of switching to exemestane versus continued tamoxifen as adjuvant therapy for postmenopausal women with primary breast cancer.
    Cancer, 2007, Aug-01, Volume: 110, Issue:3

    Topics: Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Cost-Benefit Analysis; Drug Costs; Female; Humans; Markov Chains; Middle Aged; Neoplasm Recurrence, Local; Postmenopause; Quality-Adjusted Life Years; SEER Program; Selective Estrogen Receptor Modulators; Sensitivity and Specificity; Survival Rate; Tamoxifen

2007
Chemoprevention of breast cancer.
    Breast cancer (Tokyo, Japan), 2008, Volume: 15, Issue:1

    Topics: Androstadienes; Anticarcinogenic Agents; Aromatase Inhibitors; Breast Neoplasms; Chemoprevention; Clinical Trials as Topic; Female; Humans; Raloxifene Hydrochloride; Tamoxifen

2008
Exemestane: the dawn of a new era in breast cancer treatment.
    Journal of cancer research and clinical oncology, 2008, Volume: 134, Issue:7

    Topics: Androstadienes; Antineoplastic Agents; Breast Neoplasms; Female; Humans

2008
[Efficacy of sequential treatment with anastrozole following exemestane compared with exemestane following anastrozole in patients with metastatic breast cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Middle Aged; Neoplasm Metastasis; Nitriles; Retrospective Studies; Survival Rate; Triazoles

2008
Update: a 62-year-old woman with a new diagnosis of breast cancer.
    JAMA, 2008, Mar-05, Volume: 299, Issue:9

    Topics: Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Carcinoma, Lobular; Chemotherapy, Adjuvant; Female; Humans; Middle Aged; Tamoxifen

2008
Premenopausal endocrine-responsive early breast cancer: who receives chemotherapy?
    Annals of oncology : official journal of the European Society for Medical Oncology, 2008, Volume: 19, Issue:7

    Topics: Androstadienes; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Decision Making; Female; Goserelin; Humans; Premenopause; Randomized Controlled Trials as Topic; Tamoxifen

2008
Controversies in endocrine treatment: effective utilization of steroidal and nonsteroidal aromatase inhibitors: now and in the future. Forward.
    Anti-cancer drugs, 2008, Volume: 19 Suppl 2

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Drug Resistance, Neoplasm; Female; Humans; Letrozole; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Tamoxifen; Triazoles

2008
Estrogen regulated gene expression in response to neoadjuvant endocrine therapy of breast cancers: tamoxifen agonist effects dominate in the presence of an aromatase inhibitor.
    Breast cancer research and treatment, 2008, Volume: 112, Issue:3

    Topics: Androstadienes; Animals; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Estrogens; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Nude; Receptors, Estrogen; Tamoxifen

2008
Exemestane: an alternative treatment option in early breast cancer. Foreward.
    Anti-cancer drugs, 2008, Volume: 19 Suppl 1

    Topics: Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Postmenopause

2008
Intergroup Exemestane Study mature analysis: overall survival data.
    Anti-cancer drugs, 2008, Volume: 19 Suppl 1

    Topics: Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Neoplasms, Hormone-Dependent; Postmenopause; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Survival Rate; Tamoxifen

2008
The role of amphiregulin in exemestane-resistant breast cancer cells: evidence of an autocrine loop.
    Cancer research, 2008, Apr-01, Volume: 68, Issue:7

    Topics: Amphiregulin; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Cell Growth Processes; Cell Line, Tumor; Drug Resistance, Neoplasm; EGF Family of Proteins; ErbB Receptors; Glycoproteins; Humans; Intercellular Signaling Peptides and Proteins; Mitogen-Activated Protein Kinases; Receptors, Estrogen; Recombinant Proteins; RNA, Small Interfering

2008
Planar scintimammography and SPECT in neoadjuvant chemo or hormonotherapy response evaluation in locally advanced primary breast cancer.
    International journal of oncology, 2008, Volume: 32, Issue:6

    Topics: Adenocarcinoma, Mucinous; Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Female; Humans; Lymph Nodes; Mammography; Mass Screening; Middle Aged; Neoadjuvant Therapy; Organophosphorus Compounds; Organotechnetium Compounds; Prognosis; Radiopharmaceuticals; Sensitivity and Specificity; Tomography, Emission-Computed, Single-Photon

2008
Endocrinological and clinical evaluation of exemestane, a new steroidal aromatase inhibitor.
    British journal of cancer, 1995, Volume: 72, Issue:4

    Topics: Adult; Aged; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Estradiol; Estriol; Female; Humans; Luteinizing Hormone; Middle Aged; Sex Hormone-Binding Globulin

1995
Plasma changes in breast cancer patients during endocrine therapy--lipid measurements and nuclear magnetic resonance (NMR) spectroscopy.
    Breast cancer research and treatment, 1995, Volume: 36, Issue:3

    Topics: Androstadienes; Antineoplastic Agents, Hormonal; Breast Neoplasms; Dexamethasone; Enzyme Inhibitors; Female; Humans; Lipids; Magnetic Resonance Spectroscopy; Tamoxifen

1995
Influence of aromatase inhibitors on plasma total homocysteine in postmenopausal breast cancer patients.
    Clinical chemistry, 1999, Volume: 45, Issue:2

    Topics: Aminoglutethimide; Androstadienes; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Creatinine; Enzyme Inhibitors; Estrogen Antagonists; Homocysteine; Humans; Postmenopause; Vitamins

1999
Exemestane for advanced breast cancer.
    The Medical letter on drugs and therapeutics, 2000, Apr-17, Volume: 42, Issue:1076

    Topics: Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Female; Hot Flashes; Humans; Intestinal Absorption; Liver; Middle Aged; Mixed Function Oxygenases; Postmenopause

2000
[Aromatase inhibitors in the treatment of breast cancer].
    Revue medicale de la Suisse romande, 2000, Volume: 120, Issue:6

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; Letrozole; Nitriles; Triazoles

2000
Longer time to tumor progression with exemestane vs tamoxifen in advanced breast cancer.
    Oncology (Williston Park, N.Y.), 2000, Volume: 14, Issue:9

    Topics: Androstadienes; Antineoplastic Agents, Hormonal; Breast Neoplasms; Clinical Trials as Topic; Female; Humans; Tamoxifen

2000
Steroidal side effects of exemestane.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2001, Apr-01, Volume: 19, Issue:7

    Topics: Androstadienes; Antineoplastic Agents; Breast Neoplasms; Female; Humans; Hyperandrogenism

2001
Aromatase inhibitors and inactivators in breast cancer.
    BMJ (Clinical research ed.), 2001, Oct-20, Volume: 323, Issue:7318

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Estrogen Antagonists; Estrogens; Female; Humans; Letrozole; Nitriles; Tamoxifen; Triazoles

2001
The MORE trial: multiple outcomes for raloxifene evaluation--breast cancer as a secondary end point: implications for prevention.
    Annals of the New York Academy of Sciences, 2001, Volume: 949

    Topics: Aged; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Female; Humans; Incidence; Raloxifene Hydrochloride; Randomized Controlled Trials as Topic; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Tamoxifen; White People

2001
Local endocrine effects of aromatase inhibitors within the breast.
    The Journal of steroid biochemistry and molecular biology, 2001, Volume: 79, Issue:1-5

    Topics: Anastrozole; Androstadienes; Aromatase; Aromatase Inhibitors; Breast; Breast Neoplasms; Cells, Cultured; Chemotherapy, Adjuvant; Enzyme Inhibitors; Estrogens; Estrone; Female; Fibroblasts; Humans; In Vitro Techniques; Letrozole; Neoplasms, Hormone-Dependent; Nitriles; Triazoles

2001
[Aromatase inhibitors of the 3rd generation. What can the "pill against breast cancer" really do?].
    MMW Fortschritte der Medizin, 2002, Jan-31, Volume: 144, Issue:5

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials, Phase III as Topic; Enzyme Inhibitors; Humans; Letrozole; Nitriles; Triazoles

2002
Cost-effectiveness analysis of exemestane compared with megestrol in advanced breast cancer: a model for Europe and Australia.
    PharmacoEconomics, 2002, Volume: 20, Issue:2

    Topics: Aged; Algorithms; Androstadienes; Antineoplastic Agents, Hormonal; Australia; Breast Neoplasms; Cost-Benefit Analysis; Europe; Female; Humans; Megestrol; Middle Aged; Models, Economic

2002
New breast cancer drugs expand treatment options.
    Harvard women's health watch, 2002, Volume: 9, Issue:8

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Female; Humans; Letrozole; Nitriles; Tamoxifen; Triazoles

2002
Comparison of in vitro exemestane activity versus other antiaromatase agents.
    Clinical breast cancer, 2000, Volume: 1 Suppl 1

    Topics: Aminoglutethimide; Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Choriocarcinoma; Female; Humans; Nitriles; Triazoles; Tumor Cells, Cultured

2000
Estrogen as therapy for breast cancer.
    Breast cancer research : BCR, 2002, Volume: 4, Issue:4

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Breast Neoplasms; Clinical Trials, Phase II as Topic; Diethylstilbestrol; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Estrogens; Female; Humans; Letrozole; Megestrol Acetate; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Salvage Therapy; Tamoxifen; Treatment Outcome; Triazoles

2002