aristolochic acid i has been researched along with Wilms Tumor in 1 studies
aristolochic acid I: phospholipase A inhibitor
aristolochic acid A : An aristolochic acid that is phenanthrene-1-carboxylic acid that is substituted by a methylenedioxy group at the 3,4 positions, by a methoxy group at position 8, and by a nitro group at position 10. It is the most abundant of the aristolochic acids and is found in almost all Aristolochia (birthworts or pipevines) species. It has been tried in a number of treatments for inflammatory disorders, mainly in Chinese and folk medicine. However, there is concern over their use as aristolochic acid is both carcinogenic and nephrotoxic.
Wilms Tumor: A malignant kidney tumor, caused by the uncontrolled multiplication of renal stem (blastemal), stromal (STROMAL CELLS), and epithelial (EPITHELIAL CELLS) elements. However, not all three are present in every case. Several genes or chromosomal areas have been associated with Wilms tumor which is usually found in childhood as a firm lump in a child's side or ABDOMEN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "1) Administration of large dosage of Aristolochia manshuriensis Kom induces acute renal failure in rats." | 1.31 | Long-term outcome of acute renal injury induced by Aristolochia manshuriensis Kom in rats. ( Chen, HP; Li, LS; Liu, ZH; Qiu, Q; Yin, HL, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Qiu, Q | 1 |
| Liu, ZH | 1 |
| Chen, HP | 1 |
| Yin, HL | 1 |
| Li, LS | 1 |
1 other study available for aristolochic acid i and Wilms Tumor
| Article | Year |
|---|---|
Long-term outcome of acute renal injury induced by Aristolochia manshuriensis Kom in rats.
Topics: Acute Kidney Injury; Animals; Aristolochia; Drugs, Chinese Herbal; Female; Kidney; Kidney Neoplasms; | 2000 |