aristolochic acid i has been researched along with Weight Gain in 2 studies
aristolochic acid I: phospholipase A inhibitor
aristolochic acid A : An aristolochic acid that is phenanthrene-1-carboxylic acid that is substituted by a methylenedioxy group at the 3,4 positions, by a methoxy group at position 8, and by a nitro group at position 10. It is the most abundant of the aristolochic acids and is found in almost all Aristolochia (birthworts or pipevines) species. It has been tried in a number of treatments for inflammatory disorders, mainly in Chinese and folk medicine. However, there is concern over their use as aristolochic acid is both carcinogenic and nephrotoxic.
Weight Gain: Increase in BODY WEIGHT over existing weight.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Pattern recognition analysis indicated that the renal proximal tubule lesion was the main damage induced by AA, and the renal toxicity induced by AA was a progressive course with the accumulation of dosage by monitoring the toxicological processes from onset, development and part-recovery." | 1.33 | NMR-based metabonomic study on the subacute toxicity of aristolochic acid in rats. ( Li, X; Liao, P; Ni, J; Pei, F; Wu, H; Zhang, X, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hu, X | 1 |
| Shen, J | 1 |
| Pu, X | 1 |
| Zheng, N | 1 |
| Deng, Z | 1 |
| Zhang, Z | 1 |
| Li, H | 1 |
| Zhang, X | 1 |
| Wu, H | 1 |
| Liao, P | 1 |
| Li, X | 1 |
| Ni, J | 1 |
| Pei, F | 1 |
2 other studies available for aristolochic acid i and Weight Gain
| Article | Year |
|---|---|
Urinary Time- or Dose-Dependent Metabolic Biomarkers of Aristolochic Acid-Induced Nephrotoxicity in Rats.
Topics: Animals; Aristolochic Acids; Biomarkers; Carcinogens; Citric Acid; Creatinine; Dose-Response Relatio | 2017 |
NMR-based metabonomic study on the subacute toxicity of aristolochic acid in rats.
Topics: Animals; Aristolochic Acids; Blood Chemical Analysis; Body Weight; Chemical and Drug Induced Liver I | 2006 |