aristolochic acid i has been researched along with Ureteral Neoplasms in 12 studies
aristolochic acid I: phospholipase A inhibitor
aristolochic acid A : An aristolochic acid that is phenanthrene-1-carboxylic acid that is substituted by a methylenedioxy group at the 3,4 positions, by a methoxy group at position 8, and by a nitro group at position 10. It is the most abundant of the aristolochic acids and is found in almost all Aristolochia (birthworts or pipevines) species. It has been tried in a number of treatments for inflammatory disorders, mainly in Chinese and folk medicine. However, there is concern over their use as aristolochic acid is both carcinogenic and nephrotoxic.
Ureteral Neoplasms: Cancer or tumors of the URETER which may cause obstruction leading to hydroureter, HYDRONEPHROSIS, and PYELONEPHRITIS. HEMATURIA is a common symptom.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The role of aristolochic acid in the etiology of Balkan endemic nephropathy (BEN) and associated upper urothelial carcinoma (UUC) was recently confirmed." | 3.75 | Molecular markers in upper urothelial carcinoma associated to Balkan endemic nephropathy. Aristolochic acid as the major risk factor of the worldwide disease. ( Hattori, T; Jankovic Velickovic, L; Stefanovic, V, 2009) |
| "Balkan endemic nephropathy is a chronic tubulointerstitial disease with insidious onset, slowly progressing to end-stage renal disease and frequently associated with urothelial carcinoma of the upper urinary tract (UTUC)." | 2.61 | Balkan Endemic Nephropathy and the Causative Role of Aristolochic Acid. ( Arlt, VM; Colet, JM; Dika, Ž; Jelaković, B; Nikolić, J; Nortier, JL; Pavlović, NM; Stiborova, M; Vanherweghem, JL, 2019) |
| "UTUC and bladder cancer share some common risk factors, even if they are two different entities regarding practical, biological and clinical characteristics." | 2.55 | Epidemiology, diagnosis, preoperative evaluation and prognostic assessment of upper-tract urothelial carcinoma (UTUC). ( Babjuk, M; Chade, DC; Fernández, MI; Fritsche, HM; Grollman, AP; Kassouf, W; Kikuchi, E; Lerner, SP; Lotan, Y; Rink, M; Shariat, SF; Soria, F; Spiess, PE; Thalmann, GN; Ye, D, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 6 (50.00) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Dickman, KG | 2 |
| Chen, CH | 2 |
| Grollman, AP | 3 |
| Pu, YS | 2 |
| Li, S | 1 |
| Zhang, J | 1 |
| Tian, Y | 1 |
| Zhu, Y | 1 |
| Guo, Y | 1 |
| Wang, Z | 1 |
| Yang, Y | 1 |
| Ding, G | 1 |
| Lin, J | 1 |
| Shao, IH | 1 |
| Chang, YH | 1 |
| Pang, ST | 1 |
| Jelaković, B | 1 |
| Dika, Ž | 1 |
| Arlt, VM | 3 |
| Stiborova, M | 1 |
| Pavlović, NM | 1 |
| Nikolić, J | 1 |
| Colet, JM | 1 |
| Vanherweghem, JL | 1 |
| Nortier, JL | 1 |
| Soria, F | 1 |
| Shariat, SF | 1 |
| Lerner, SP | 1 |
| Fritsche, HM | 1 |
| Rink, M | 1 |
| Kassouf, W | 1 |
| Spiess, PE | 1 |
| Lotan, Y | 1 |
| Ye, D | 1 |
| Fernández, MI | 1 |
| Kikuchi, E | 1 |
| Chade, DC | 1 |
| Babjuk, M | 1 |
| Thalmann, GN | 1 |
| Jankovic Velickovic, L | 1 |
| Hattori, T | 1 |
| Stefanovic, V | 1 |
| Moriya, M | 1 |
| Zavadil, J | 1 |
| Sidorenko, VS | 1 |
| Edwards, KL | 1 |
| Gnatenko, DV | 1 |
| Wu, L | 1 |
| Turesky, RJ | 1 |
| Wu, XR | 1 |
| Schetter, AJ | 1 |
| Harris, CC | 1 |
| Lord, GM | 2 |
| Hollstein, M | 2 |
| Roufosse, C | 1 |
| Pusey, CD | 2 |
| Cook, T | 2 |
| Schmeiser, HH | 3 |
| Cosyns, JP | 1 |
| Jadoul, M | 1 |
| Squifflet, JP | 1 |
| Wese, FX | 1 |
| van Ypersele de Strihou, C | 1 |
| Williams, G | 1 |
| Olivier, M | 1 |
| Straif, K | 1 |
| Wild, CP | 1 |
4 reviews available for aristolochic acid i and Ureteral Neoplasms
| Article | Year |
|---|---|
Aristolochic acid-containing Chinese herbal medicine and upper urinary tract urothelial carcinoma in Taiwan: a narrative review.
Topics: Aristolochic Acids; Carcinogens; Carcinoma, Transitional Cell; DNA Adducts; Drugs, Chinese Herbal; F | 2023 |
Recent advances in upper tract urothelial carcinomas: From bench to clinics.
Topics: Animals; Antineoplastic Agents; Aristolochic Acids; Arsenic; Carcinogens; Carcinoma, Transitional Ce | 2019 |
Balkan Endemic Nephropathy and the Causative Role of Aristolochic Acid.
Topics: Animals; Aristolochia; Aristolochic Acids; Balkan Nephropathy; Carcinogens; Carcinoma, Transitional | 2019 |
Epidemiology, diagnosis, preoperative evaluation and prognostic assessment of upper-tract urothelial carcinoma (UTUC).
Topics: Aristolochic Acids; Carcinoma, Transitional Cell; Colorectal Neoplasms, Hereditary Nonpolyposis; Hum | 2017 |
8 other studies available for aristolochic acid i and Ureteral Neoplasms
| Article | Year |
|---|---|
De novo upper tract urothelial carcinoma after renal transplantation: a single-center experience in China.
Topics: Carcinoma, Transitional Cell; Humans; Kidney Transplantation; Neoplasm Recurrence, Local; Prognosis; | 2023 |
Molecular markers in upper urothelial carcinoma associated to Balkan endemic nephropathy. Aristolochic acid as the major risk factor of the worldwide disease.
Topics: Adult; Aged; Aged, 80 and over; Aristolochia; Aristolochic Acids; Balkan Nephropathy; Biomarkers, Tu | 2009 |
Aristolochic acid-associated urothelial cancer in Taiwan.
Topics: Adult; Aged; Aged, 80 and over; Aristolochic Acids; Carcinoma, Renal Cell; Carcinoma, Transitional C | 2012 |
Tumor suppressor p53 (TP53) at the crossroads of the exposome and the cancer genome.
Topics: Aristolochic Acids; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Drugs, Chinese Herbal; Fema | 2012 |
DNA adducts and p53 mutations in a patient with aristolochic acid-associated nephropathy.
Topics: Aristolochia; Aristolochic Acids; Breast Neoplasms; DNA Adducts; Female; Genes, p53; Humans; Kidney | 2004 |
Urothelial lesions in Chinese-herb nephropathy.
Topics: Adult; Aristolochic Acids; Carcinogens; Carcinoma in Situ; Carcinoma, Transitional Cell; Drugs, Chin | 1999 |
Urothelial malignant disease and Chinese herbal nephropathy.
Topics: Aristolochic Acids; Carcinogens; Carcinoma, Transitional Cell; Drugs, Chinese Herbal; Female; Humans | 2001 |
Upper urinary tract urothelial cancers: where it is A:T.
Topics: Aristolochia; Humans; Plant Extracts; Plants, Medicinal; Ureteral Neoplasms; Urologic Neoplasms | 2012 |