aristolochic acid i has been researched along with Uremia in 2 studies
aristolochic acid I: phospholipase A inhibitor
aristolochic acid A : An aristolochic acid that is phenanthrene-1-carboxylic acid that is substituted by a methylenedioxy group at the 3,4 positions, by a methoxy group at position 8, and by a nitro group at position 10. It is the most abundant of the aristolochic acids and is found in almost all Aristolochia (birthworts or pipevines) species. It has been tried in a number of treatments for inflammatory disorders, mainly in Chinese and folk medicine. However, there is concern over their use as aristolochic acid is both carcinogenic and nephrotoxic.
Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "All incident cases of chronic renal failure reported to the Database of Catastrophic Illness of the National Health Insurance Bureau between 1995 and 2000 were defined as the case group." | 1.37 | Occupational kidney disease among Chinese herbalists exposed to herbs containing aristolochic acids. ( Chen, PC; Lo, TC; Wang, JD; Yang, HY, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, JF | 1 |
| Hsieh, CY | 1 |
| Lu, KC | 1 |
| Chen, YW | 1 |
| Liang, SS | 1 |
| Lin, CC | 1 |
| Hung, CF | 1 |
| Liou, JC | 1 |
| Wu, MS | 1 |
| Yang, HY | 1 |
| Wang, JD | 1 |
| Lo, TC | 1 |
| Chen, PC | 1 |
2 other studies available for aristolochic acid i and Uremia
| Article | Year |
|---|---|
Therapeutic Targeting of Aristolochic Acid Induced Uremic Toxin Retention, SMAD 2/3 and JNK/ERK Pathways in Tubulointerstitial Fibrosis: Nephroprotective Role of Propolis in Chronic Kidney Disease.
Topics: Animals; Aristolochic Acids; Cresols; Disease Models, Animal; Epithelial-Mesenchymal Transition; Ext | 2020 |
Occupational kidney disease among Chinese herbalists exposed to herbs containing aristolochic acids.
Topics: Adult; Aged; Aristolochic Acids; Case-Control Studies; Drug Compounding; Drug Contamination; Drugs, | 2011 |