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aristolochic acid i and Polyploid

aristolochic acid i has been researched along with Polyploid in 1 studies

aristolochic acid I: phospholipase A inhibitor
aristolochic acid A : An aristolochic acid that is phenanthrene-1-carboxylic acid that is substituted by a methylenedioxy group at the 3,4 positions, by a methoxy group at position 8, and by a nitro group at position 10. It is the most abundant of the aristolochic acids and is found in almost all Aristolochia (birthworts or pipevines) species. It has been tried in a number of treatments for inflammatory disorders, mainly in Chinese and folk medicine. However, there is concern over their use as aristolochic acid is both carcinogenic and nephrotoxic.

Research Excerpts

ExcerptRelevanceReference
" We used the Fucci mouse in conjunction with FlowSight to identify a discrete polyploid population in proximal tubules after aristolochic acid injury."3.91Novel kidney dissociation protocol and image-based flow cytometry facilitate improved analysis of injured proximal tubules. ( Alford, CE; Flaherty, DK; Gewin, LS; Ivanova, A; Lau, KS; Manolopoulou, M; Matlock, BK; Nlandu-Khodo, S; Phillips-Mignemi, M; Simmons, AJ, 2019)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Manolopoulou, M1
Matlock, BK1
Nlandu-Khodo, S1
Simmons, AJ1
Lau, KS1
Phillips-Mignemi, M1
Ivanova, A1
Alford, CE1
Flaherty, DK1
Gewin, LS1

Other Studies

1 other study available for aristolochic acid i and Polyploid

ArticleYear
Novel kidney dissociation protocol and image-based flow cytometry facilitate improved analysis of injured proximal tubules.
    American journal of physiology. Renal physiology, 2019, 05-01, Volume: 316, Issue:5

    Topics: Acute Kidney Injury; Animals; Aristolochic Acids; Biomarkers; Cell Cycle; Cell Separation; Disease M

2019