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aristolochic acid i and Nephritis

aristolochic acid i has been researched along with Nephritis in 8 studies

aristolochic acid I: phospholipase A inhibitor
aristolochic acid A : An aristolochic acid that is phenanthrene-1-carboxylic acid that is substituted by a methylenedioxy group at the 3,4 positions, by a methoxy group at position 8, and by a nitro group at position 10. It is the most abundant of the aristolochic acids and is found in almost all Aristolochia (birthworts or pipevines) species. It has been tried in a number of treatments for inflammatory disorders, mainly in Chinese and folk medicine. However, there is concern over their use as aristolochic acid is both carcinogenic and nephrotoxic.

Nephritis: Inflammation of any part of the KIDNEY.

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's3 (37.50)29.6817
2010's4 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Li, S1
Mariappan, N1
Megyesi, J1
Shank, B1
Kannan, K1
Theus, S1
Price, PM1
Duffield, JS1
Portilla, D1
Tian, Y1
Liao, F1
Wu, G2
Chang, D1
Yang, Y1
Dong, X1
Zhang, Z1
Zhang, Y1
Pozdzik, AA1
Berton, A1
Schmeiser, HH2
Missoum, W1
Decaestecker, C1
Salmon, IJ1
Vanherweghem, JL1
Nortier, JL1
Jia, W1
Zhao, A1
Gao, W1
Chen, M1
Xiao, P1
Huang, S1
Konieczkowski, M1
Schelling, JR1
Sedor, JR1
Stiborová, M1
Frei, E1
Sopko, B1
Wiessler, M1
Ernst, E1
Li, YM1

Other Studies

8 other studies available for aristolochic acid i and Nephritis

ArticleYear
Proximal tubule PPARα attenuates renal fibrosis and inflammation caused by unilateral ureteral obstruction.
    American journal of physiology. Renal physiology, 2013, Sep-01, Volume: 305, Issue:5

    Topics: Animals; Arginase; Aristolochic Acids; B7-2 Antigen; Collagen Type I; Collagen Type IV; Down-Regulat

2013
Ubiquitination and regulation of Smad7 in the TGF-β1/Smad signaling of aristolochic acid nephropathy.
    Toxicology mechanisms and methods, 2015, Volume: 25, Issue:8

    Topics: Animals; Aristolochic Acids; Carcinogens; Cells, Cultured; Dose-Response Relationship, Drug; Gene Ex

2015
Aristolochic acid nephropathy revisited: a place for innate and adaptive immunity?
    Histopathology, 2010, Volume: 56, Issue:4

    Topics: Adaptive Immunity; Adult; Aged; Aristolochic Acids; Case-Control Studies; Disease Progression; Drugs

2010
New perspectives on the Chinese herbal nephropathy.
    Phytotherapy research : PTR, 2005, Volume: 19, Issue:11

    Topics: Anti-Obesity Agents; Aristolochic Acids; Drugs, Chinese Herbal; Herb-Drug Interactions; Nephritis

2005
Interleukin-1 stimulates Jun N-terminal/stress-activated protein kinase by an arachidonate-dependent mechanism in mesangial cells.
    Kidney international, 1999, Volume: 55, Issue:5

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 8,11,14-Eicosatrienoic Acid; Ani

1999
Carcinogenic aristolochic acids upon activation by DT-diaphorase form adducts found in DNA of patients with Chinese herbs nephropathy.
    Carcinogenesis, 2002, Volume: 23, Issue:4

    Topics: Aldehyde Oxidase; Aldehyde Oxidoreductases; Animals; Antineoplastic Agents; Aristolochic Acids; Carc

2002
Aristolochia, a herbal treatment to die for?
    Maturitas, 2012, Volume: 73, Issue:2

    Topics: Aristolochia; Aristolochic Acids; Humans; Neoplasms; Nephritis; Phytotherapy; Plant Extracts

2012
[Query on the cause of "belgium nephropathy" (Chinese herb nephropathy) and the speculation on carcinogenesis of Chinese herbs].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2002, Volume: 22, Issue:2

    Topics: Aristolochia; Aristolochic Acids; Belgium; Drugs, Chinese Herbal; Humans; Kidney Neoplasms; Nephriti

2002