Page last updated: 2024-10-22

aristolochic acid i and Malaria

aristolochic acid i has been researched along with Malaria in 2 studies

aristolochic acid I: phospholipase A inhibitor
aristolochic acid A : An aristolochic acid that is phenanthrene-1-carboxylic acid that is substituted by a methylenedioxy group at the 3,4 positions, by a methoxy group at position 8, and by a nitro group at position 10. It is the most abundant of the aristolochic acids and is found in almost all Aristolochia (birthworts or pipevines) species. It has been tried in a number of treatments for inflammatory disorders, mainly in Chinese and folk medicine. However, there is concern over their use as aristolochic acid is both carcinogenic and nephrotoxic.

Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.

Research Excerpts

ExcerptRelevanceReference
" The locals used these plant parts to prepare infusion and decoction traditional dosage forms for oral use."1.62Ethno medical knowledge and traditional use of Aristolochia bracteolata Lam. for malaria among local communities in Jubek State of South Sudan: A cross-sectional survey. ( Deng, AL; Mathew, LS; Ogwang, PE; Peter, EL; Tolo, CU; Weisheit, A, 2021)
" The isolated toxic compounds were purified through RP-HPLC."1.42Toxicity of aristolochic acids isolated from Aristolochia indica Linn (Aristolochiaceae) against the malarial vector Anopheles stephensi Liston (Diptera: Culicidae). ( Kirubakaran, SA; Pradeepa, V; Sathish-Narayanan, S; Senthil-Nathan, S; Thanigaivel, A, 2015)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Pradeepa, V1
Sathish-Narayanan, S1
Kirubakaran, SA1
Thanigaivel, A1
Senthil-Nathan, S1
Mathew, LS1
Peter, EL1
Weisheit, A1
Tolo, CU1
Deng, AL1
Ogwang, PE1

Other Studies

2 other studies available for aristolochic acid i and Malaria

ArticleYear
Toxicity of aristolochic acids isolated from Aristolochia indica Linn (Aristolochiaceae) against the malarial vector Anopheles stephensi Liston (Diptera: Culicidae).
    Experimental parasitology, 2015, Volume: 153

    Topics: Aedes; Animals; Aristolochia; Aristolochic Acids; Humans; Insect Vectors; Insecticides; Larva; Malar

2015
Ethno medical knowledge and traditional use of Aristolochia bracteolata Lam. for malaria among local communities in Jubek State of South Sudan: A cross-sectional survey.
    Journal of ethnopharmacology, 2021, Oct-28, Volume: 279

    Topics: Adolescent; Adult; Antimalarials; Aristolochia; Cross-Sectional Studies; Female; Health Knowledge, A

2021