aristolochic acid i has been researched along with Hypokalemia in 2 studies
aristolochic acid I: phospholipase A inhibitor
aristolochic acid A : An aristolochic acid that is phenanthrene-1-carboxylic acid that is substituted by a methylenedioxy group at the 3,4 positions, by a methoxy group at position 8, and by a nitro group at position 10. It is the most abundant of the aristolochic acids and is found in almost all Aristolochia (birthworts or pipevines) species. It has been tried in a number of treatments for inflammatory disorders, mainly in Chinese and folk medicine. However, there is concern over their use as aristolochic acid is both carcinogenic and nephrotoxic.
Hypokalemia: Abnormally low potassium concentration in the blood. It may result from potassium loss by renal secretion or by the gastrointestinal route, as by vomiting or diarrhea. It may be manifested clinically by neuromuscular disorders ranging from weakness to paralysis, by electrocardiographic abnormalities (depression of the T wave and elevation of the U wave), by renal disease, and by gastrointestinal disorders. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study was designed to investigate the roles of aristolochic acid I (AA-I) and hypokalemia in acute aristolochic acid nephropathy (AAN)." | 7.88 | Effects of aristolochic acid I and/or hypokalemia on tubular damage in C57BL/6 rat with aristolochic acid nephropathy. ( Han, SW; Kim, J; Kim, WY; Park, MH; Yi, JH, 2018) |
| "This study was designed to investigate the roles of aristolochic acid I (AA-I) and hypokalemia in acute aristolochic acid nephropathy (AAN)." | 3.88 | Effects of aristolochic acid I and/or hypokalemia on tubular damage in C57BL/6 rat with aristolochic acid nephropathy. ( Han, SW; Kim, J; Kim, WY; Park, MH; Yi, JH, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yi, JH | 1 |
| Han, SW | 1 |
| Kim, WY | 1 |
| Kim, J | 1 |
| Park, MH | 1 |
| Yang, SS | 1 |
| Chu, P | 1 |
| Lin, YF | 1 |
| Chen, A | 1 |
| Lin, SH | 1 |
2 other studies available for aristolochic acid i and Hypokalemia
| Article | Year |
|---|---|
Effects of aristolochic acid I and/or hypokalemia on tubular damage in C57BL/6 rat with aristolochic acid nephropathy.
Topics: Animals; Aristolochic Acids; Disease Models, Animal; Hypokalemia; Kidney Diseases; Kidney Tubules; M | 2018 |
Aristolochic acid-induced Fanconi's syndrome and nephropathy presenting as hypokalemic paralysis.
Topics: Acute Kidney Injury; Aristolochic Acids; Drugs, Chinese Herbal; Fanconi Syndrome; Humans; Hypokalemi | 2002 |