aristolochic acid i has been researched along with Hematologic Malignancies in 1 studies
aristolochic acid I: phospholipase A inhibitor
aristolochic acid A : An aristolochic acid that is phenanthrene-1-carboxylic acid that is substituted by a methylenedioxy group at the 3,4 positions, by a methoxy group at position 8, and by a nitro group at position 10. It is the most abundant of the aristolochic acids and is found in almost all Aristolochia (birthworts or pipevines) species. It has been tried in a number of treatments for inflammatory disorders, mainly in Chinese and folk medicine. However, there is concern over their use as aristolochic acid is both carcinogenic and nephrotoxic.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The correlation of cancer incidence with age, gender, dosage of aristolochic acid (AA), the type of renal replacement therapies, and the polymorphisms of quinone oxidoreductase 1 (NQO1) C609T and cytochrome P450 1A1 (CYP1A1) A4889G was examined." | 1.42 | Analysis of potential risk factors for cancer incidence in patients with aristolochic acid nephropathy from Wenzhou, China. ( Chen, C; Lin, F; Liu, Y; Sun, M; Xu, F; Zhang, J; Zheng, C, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sun, M | 1 |
| Zhang, J | 1 |
| Zheng, C | 1 |
| Liu, Y | 1 |
| Lin, F | 1 |
| Xu, F | 1 |
| Chen, C | 1 |
1 other study available for aristolochic acid i and Hematologic Malignancies
| Article | Year |
|---|---|
Analysis of potential risk factors for cancer incidence in patients with aristolochic acid nephropathy from Wenzhou, China.
Topics: Aged; Aristolochic Acids; Carcinogens; China; Cytochrome P-450 CYP1A1; Female; Hematologic Neoplasms | 2015 |