aristolochic acid i has been researched along with Heart Failure in 2 studies
aristolochic acid I: phospholipase A inhibitor
aristolochic acid A : An aristolochic acid that is phenanthrene-1-carboxylic acid that is substituted by a methylenedioxy group at the 3,4 positions, by a methoxy group at position 8, and by a nitro group at position 10. It is the most abundant of the aristolochic acids and is found in almost all Aristolochia (birthworts or pipevines) species. It has been tried in a number of treatments for inflammatory disorders, mainly in Chinese and folk medicine. However, there is concern over their use as aristolochic acid is both carcinogenic and nephrotoxic.
Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lam, NT | 1 |
| Currie, PD | 1 |
| Lieschke, GJ | 1 |
| Rosenthal, NA | 1 |
| Kaye, DM | 1 |
| Huang, CC | 1 |
| Chen, PC | 1 |
| Huang, CW | 1 |
| Yu, J | 1 |
2 other studies available for aristolochic acid i and Heart Failure
| Article | Year |
|---|---|
Nerve growth factor stimulates cardiac regeneration via cardiomyocyte proliferation in experimental heart failure.
Topics: Animals; Animals, Genetically Modified; Apoptosis; Aristolochic Acids; Cell Proliferation; Heart; He | 2012 |
Aristolochic Acid induces heart failure in zebrafish embryos that is mediated by inflammation.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aristolochic Acids; Cyclooxygenase 2; Cyclooxygen | 2007 |