aristolochic acid i has been researched along with Heart Diseases in 1 studies
aristolochic acid I: phospholipase A inhibitor
aristolochic acid A : An aristolochic acid that is phenanthrene-1-carboxylic acid that is substituted by a methylenedioxy group at the 3,4 positions, by a methoxy group at position 8, and by a nitro group at position 10. It is the most abundant of the aristolochic acids and is found in almost all Aristolochia (birthworts or pipevines) species. It has been tried in a number of treatments for inflammatory disorders, mainly in Chinese and folk medicine. However, there is concern over their use as aristolochic acid is both carcinogenic and nephrotoxic.
Heart Diseases: Pathological conditions involving the HEART including its structural and functional abnormalities.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study, the effect of ethyl acetate extract of Nan Mu Xiang (NMX) on cardiac fibrosis was assessed in vitro by cultured adult rat cardiac fibroblasts with angiotensin II (AngII) stimulation, and in vivo by rats with abdominal aorta constriction (AAC)." | 7.80 | Inhibitory effect of ethyl acetate extract of Aristolochia yunnanensis on cardiac fibrosis through extracellular signal-regulated kinases 1/2 and transforming growth factor β/small mother against decapentaplegic signaling pathways. ( Chen, S; Cheng, Z; Li, C; Li, D; Li, H; Liu, P; Ma, Y; Peng, J; Shao, W; Shen, X; Yin, S; You, Y; Yu, Y; Zhou, C, 2014) |
| " In this study, the effect of ethyl acetate extract of Nan Mu Xiang (NMX) on cardiac fibrosis was assessed in vitro by cultured adult rat cardiac fibroblasts with angiotensin II (AngII) stimulation, and in vivo by rats with abdominal aorta constriction (AAC)." | 3.80 | Inhibitory effect of ethyl acetate extract of Aristolochia yunnanensis on cardiac fibrosis through extracellular signal-regulated kinases 1/2 and transforming growth factor β/small mother against decapentaplegic signaling pathways. ( Chen, S; Cheng, Z; Li, C; Li, D; Li, H; Liu, P; Ma, Y; Peng, J; Shao, W; Shen, X; Yin, S; You, Y; Yu, Y; Zhou, C, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shao, W | 1 |
| Li, D | 1 |
| Peng, J | 1 |
| Chen, S | 1 |
| Zhou, C | 1 |
| Cheng, Z | 1 |
| Yu, Y | 1 |
| Li, H | 1 |
| Li, C | 1 |
| You, Y | 1 |
| Ma, Y | 1 |
| Liu, P | 1 |
| Yin, S | 1 |
| Shen, X | 1 |
1 other study available for aristolochic acid i and Heart Diseases
| Article | Year |
|---|---|
Inhibitory effect of ethyl acetate extract of Aristolochia yunnanensis on cardiac fibrosis through extracellular signal-regulated kinases 1/2 and transforming growth factor β/small mother against decapentaplegic signaling pathways.
Topics: Acetates; Animals; Aristolochia; Fibrosis; Heart Diseases; MAP Kinase Signaling System; Plant Extrac | 2014 |