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aristolochic acid i and Experimental Neoplasms

aristolochic acid i has been researched along with Experimental Neoplasms in 7 studies

aristolochic acid I: phospholipase A inhibitor
aristolochic acid A : An aristolochic acid that is phenanthrene-1-carboxylic acid that is substituted by a methylenedioxy group at the 3,4 positions, by a methoxy group at position 8, and by a nitro group at position 10. It is the most abundant of the aristolochic acids and is found in almost all Aristolochia (birthworts or pipevines) species. It has been tried in a number of treatments for inflammatory disorders, mainly in Chinese and folk medicine. However, there is concern over their use as aristolochic acid is both carcinogenic and nephrotoxic.

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19903 (42.86)18.7374
1990's3 (42.86)18.2507
2000's0 (0.00)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rucevic, M1
Rosenquist, T1
Breen, L1
Cao, L1
Clifton, J1
Hixson, D1
Josic, D1
FILITIS, LN1
MASSAGETOV, PS1
Mengs, U2
Broschard, TH1
Wiessler, M3
von der Lieth, CW1
Schmeiser, HH3
Scherf, HR2
Janssen, JW1
Lyons, J1
Pfau, W1
Buchmann, A1
Bartram, CR1

Other Studies

7 other studies available for aristolochic acid i and Experimental Neoplasms

ArticleYear
Proteome alterations in response to aristolochic acids in experimental animal model.
    Journal of proteomics, 2012, Dec-05, Volume: 76 Spec No.

    Topics: Animals; Aristolochic Acids; Biomarkers, Tumor; Kidney; Kidney Diseases; Male; Mice; Mice, Inbred DB

2012
[On the antineoplastic activity of aristolochic acid].
    Voprosy onkologii, 1961, Volume: 7(8)

    Topics: Animals; Antineoplastic Agents; Aristolochic Acids; Neoplasms, Experimental; Phenanthrenes

1961
On the histopathogenesis of rat forestomach carcinoma caused by aristolochic acid.
    Archives of toxicology, 1983, Volume: 52, Issue:3

    Topics: Animals; Antineoplastic Agents; Aristolochic Acids; Hyperplasia; Male; Neoplasms, Experimental; Papi

1983
Translesional synthesis on DNA templates containing site-specifically placed deoxyadenosine and deoxyguanosine adducts formed by the plant carcinogen aristolochic acid.
    Carcinogenesis, 1994, Volume: 15, Issue:10

    Topics: Aristolochic Acids; Base Sequence; Binding Sites; Carcinogens; Deoxyadenosines; Deoxyguanosine; DNA;

1994
Activating mutations at codon 61 of the c-Ha-ras gene in thin-tissue sections of tumors induced by aristolochic acid in rats and mice.
    Cancer letters, 1991, Volume: 59, Issue:2

    Topics: Animals; Aristolochic Acids; Base Sequence; Codon; DNA, Neoplasm; Female; Genes, ras; Male; Mice; Mo

1991
Aristolochic acid activates ras genes in rat tumors at deoxyadenosine residues.
    Cancer research, 1990, Sep-01, Volume: 50, Issue:17

    Topics: Animals; Aristolochic Acids; Base Sequence; Carcinogens; Codon; DNA, Neoplasm; Gene Expression Regul

1990
Tumour induction in mice following exposure to aristolochic acid.
    Archives of toxicology, 1988, Volume: 61, Issue:6

    Topics: Animals; Aristolochic Acids; Female; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Phenanthre

1988