aristolochic acid i has been researched along with Edema in 6 studies
aristolochic acid I: phospholipase A inhibitor
aristolochic acid A : An aristolochic acid that is phenanthrene-1-carboxylic acid that is substituted by a methylenedioxy group at the 3,4 positions, by a methoxy group at position 8, and by a nitro group at position 10. It is the most abundant of the aristolochic acids and is found in almost all Aristolochia (birthworts or pipevines) species. It has been tried in a number of treatments for inflammatory disorders, mainly in Chinese and folk medicine. However, there is concern over their use as aristolochic acid is both carcinogenic and nephrotoxic.
Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Then, the pharmacological activities of FJHQT extract with respect to clinical use was investigated with acetic acid-induced writhing response, formalin-induced licking response and carrageenan-induced paw edema." | 3.81 | Anti-nociceptive, anti-inflammatory and toxicological evaluation of Fang-Ji-Huang-Qi-Tang in rodents. ( Chang, CW; Lin, YC; Wu, CR, 2015) |
| "Maximum edema was achieved within 45 min after the injection and persisted for at least 6 h." | 1.27 | Edema-inducing activity of phospholipase A2 purified from human synovial fluid and inhibition by aristolochic acid. ( Fawzy, AA; Franson, RC; Vishwanath, BS, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, YC | 1 |
| Chang, CW | 1 |
| Wu, CR | 1 |
| Lloret, S | 1 |
| Moreno, JJ | 2 |
| Ferrer, X | 1 |
| Ortega, E | 1 |
| Carganico, G | 1 |
| Vishwanath, BS | 3 |
| Fawzy, AA | 1 |
| Franson, RC | 1 |
| Gowda, TV | 2 |
| Kini, RM | 1 |
6 other studies available for aristolochic acid i and Edema
| Article | Year |
|---|---|
Anti-nociceptive, anti-inflammatory and toxicological evaluation of Fang-Ji-Huang-Qi-Tang in rodents.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Aristolochia; Aristolochic Acids; Astrag | 2015 |
Effect of nonapeptide fragments of uteroglobin and lipocortin I on oedema and mast cell degranulation.
Topics: Animals; Annexin A1; Aristolochic Acids; Carrageenan; Cell Degranulation; Chlorpheniramine; Dexameth | 1994 |
PLA2-induced oedema in rat skin and histamine release in rat mast cells. Evidence for involvement of lysophospholipids in the mechanism of action.
Topics: Animals; Aristolochic Acids; Cytoplasmic Granules; Dexamethasone; Edema; Histamine Release; In Vitro | 1992 |
Edema-inducing activity of phospholipase A2 purified from human synovial fluid and inhibition by aristolochic acid.
Topics: Acetophenones; Animals; Aristolochic Acids; Edema; Enzyme Activation; Female; Humans; Male; Mice; Ph | 1988 |
Interaction of aristolochic acid with Vipera russelli phospholipase A2: its effect on enzymatic and pathological activities.
Topics: Animals; Aristolochic Acids; Edema; Mice; Phenanthrenes; Phosphatidylcholines; Phospholipases; Phosp | 1987 |
Characterization of three edema-inducing phospholipase A2 enzymes from habu (Trimeresurus flavoviridis) venom and their interaction with the alkaloid aristolochic acid.
Topics: Animals; Aristolochic Acids; Biological Assay; Chemical Phenomena; Chemistry; Chromatography, Gel; E | 1987 |