aristolochic acid i has been researched along with Diseases, Occupational in 3 studies
aristolochic acid I: phospholipase A inhibitor
aristolochic acid A : An aristolochic acid that is phenanthrene-1-carboxylic acid that is substituted by a methylenedioxy group at the 3,4 positions, by a methoxy group at position 8, and by a nitro group at position 10. It is the most abundant of the aristolochic acids and is found in almost all Aristolochia (birthworts or pipevines) species. It has been tried in a number of treatments for inflammatory disorders, mainly in Chinese and folk medicine. However, there is concern over their use as aristolochic acid is both carcinogenic and nephrotoxic.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Aristolochic acid I (ALA-I) was measured by ultra-high-pressure liquid chromatography/ tandem mass spectrometry (UHPLC-MS/MS) and heavy metals in blood samples were analysed by Agilent 7500C inductively coupled plasma-mass spectrometry." | 1.39 | Association of blood lead and mercury with estimated GFR in herbalists after the ban of herbs containing aristolochic acids in Taiwan. ( Chen, PC; Chou, SA; Hwang, YH; Kao, TW; Kuo, CH; Lin, HH; Lo, TC; Yang, HY, 2013) |
| "All incident cases of chronic renal failure reported to the Database of Catastrophic Illness of the National Health Insurance Bureau between 1995 and 2000 were defined as the case group." | 1.37 | Occupational kidney disease among Chinese herbalists exposed to herbs containing aristolochic acids. ( Chen, PC; Lo, TC; Wang, JD; Yang, HY, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, HH | 1 |
| Chou, SA | 1 |
| Yang, HY | 3 |
| Hwang, YH | 1 |
| Kuo, CH | 1 |
| Kao, TW | 1 |
| Lo, TC | 3 |
| Chen, PC | 3 |
| Wang, JD | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Renal and Cardiovascular Impairment in WTC Responders: Implications for Diagnosis and Treatment[NCT02246101] | 406 participants (Actual) | Observational | 2014-07-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for aristolochic acid i and Diseases, Occupational
| Article | Year |
|---|---|
Association of blood lead and mercury with estimated GFR in herbalists after the ban of herbs containing aristolochic acids in Taiwan.
Topics: Adult; Aristolochiaceae; Aristolochic Acids; Arsenic; Cadmium; Cross-Sectional Studies; Glomerular F | 2013 |
Increased mortality risk for cancers of the kidney and other urinary organs among Chinese herbalists.
Topics: Adolescent; Adult; Aristolochic Acids; Asian People; Carcinogens; Cohort Studies; Female; Health Sur | 2009 |
Occupational kidney disease among Chinese herbalists exposed to herbs containing aristolochic acids.
Topics: Adult; Aged; Aristolochic Acids; Case-Control Studies; Drug Compounding; Drug Contamination; Drugs, | 2011 |