aristolochic acid i has been researched along with Condition, Preneoplastic in 5 studies
aristolochic acid I: phospholipase A inhibitor
aristolochic acid A : An aristolochic acid that is phenanthrene-1-carboxylic acid that is substituted by a methylenedioxy group at the 3,4 positions, by a methoxy group at position 8, and by a nitro group at position 10. It is the most abundant of the aristolochic acids and is found in almost all Aristolochia (birthworts or pipevines) species. It has been tried in a number of treatments for inflammatory disorders, mainly in Chinese and folk medicine. However, there is concern over their use as aristolochic acid is both carcinogenic and nephrotoxic.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jin, K | 2 |
| Su, KK | 2 |
| Li, T | 2 |
| Zhu, XQ | 1 |
| Wang, Q | 1 |
| Ge, RS | 1 |
| Pan, ZF | 2 |
| Wu, BW | 2 |
| Ge, LJ | 1 |
| Zhang, YH | 1 |
| Wang, YF | 2 |
| Shen, GF | 1 |
| Zhu, DY | 2 |
| Xiang, CS | 2 |
| Li, LJ | 2 |
| Lou, YJ | 2 |
| Li, L | 1 |
| Mao, ZR | 1 |
| Stemmer, K | 2 |
| Ellinger-Ziegelbauer, H | 2 |
| Ahr, HJ | 2 |
| Dietrich, DR | 2 |
| Lotz, K | 1 |
| Rossiello, MR | 1 |
| Rao, PM | 1 |
| Rajalakshmi, S | 1 |
| Sarma, DS | 1 |
5 other studies available for aristolochic acid i and Condition, Preneoplastic
| Article | Year |
|---|---|
Hepatic Premalignant Alterations Triggered by Human Nephrotoxin Aristolochic Acid I in Canines.
Topics: Administration, Oral; Animals; Aristolochia; Aristolochic Acids; Carcinogenesis; Carcinogens; Dogs; | 2016 |
Premalignant alteration assessment in liver-like tissue derived from embryonic stem cells by aristolochic acid I exposure.
Topics: Albumins; alpha-Fetoproteins; Animals; Aristolochic Acids; Biomarkers, Tumor; Cell Dedifferentiation | 2016 |
Molecular characterization of preneoplastic lesions provides insight on the development of renal tumors.
Topics: Animals; Apoptosis; Aristolochic Acids; Bromodeoxyuridine; Cell Proliferation; Gene Expression Profi | 2009 |
Establishment of a protocol for the gene expression analysis of laser microdissected rat kidney samples with affymetrix genechips.
Topics: Animals; Aristolochic Acids; Cryopreservation; Gene Expression Profiling; Kidney Neoplasms; Lasers; | 2006 |
Similar patterns of hypomethylation in the beta-hydroxy-beta-methylglutaryl coenzyme A reductase gene in hepatic nodules induced by different carcinogens.
Topics: 1,2-Dimethylhydrazine; Animals; Aristolochic Acids; Carcinogens; Cell Cycle; Dimethylhydrazines; DNA | 1994 |