aristolochic acid i has been researched along with Colorectal Neoplasms, Hereditary Nonpolyposis in 1 studies
aristolochic acid I: phospholipase A inhibitor
aristolochic acid A : An aristolochic acid that is phenanthrene-1-carboxylic acid that is substituted by a methylenedioxy group at the 3,4 positions, by a methoxy group at position 8, and by a nitro group at position 10. It is the most abundant of the aristolochic acids and is found in almost all Aristolochia (birthworts or pipevines) species. It has been tried in a number of treatments for inflammatory disorders, mainly in Chinese and folk medicine. However, there is concern over their use as aristolochic acid is both carcinogenic and nephrotoxic.
Colorectal Neoplasms, Hereditary Nonpolyposis: A group of autosomal-dominant inherited diseases in which COLON CANCER arises in discrete adenomas. Unlike FAMILIAL POLYPOSIS COLI with hundreds of polyps, hereditary nonpolyposis colorectal neoplasms occur much later, in the fourth and fifth decades. HNPCC has been associated with germline mutations in mismatch repair (MMR) genes. It has been subdivided into Lynch syndrome I or site-specific colonic cancer, and LYNCH SYNDROME II which includes extracolonic cancer.
| Excerpt | Relevance | Reference |
|---|---|---|
| "UTUC and bladder cancer share some common risk factors, even if they are two different entities regarding practical, biological and clinical characteristics." | 2.55 | Epidemiology, diagnosis, preoperative evaluation and prognostic assessment of upper-tract urothelial carcinoma (UTUC). ( Babjuk, M; Chade, DC; Fernández, MI; Fritsche, HM; Grollman, AP; Kassouf, W; Kikuchi, E; Lerner, SP; Lotan, Y; Rink, M; Shariat, SF; Soria, F; Spiess, PE; Thalmann, GN; Ye, D, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Soria, F | 1 |
| Shariat, SF | 1 |
| Lerner, SP | 1 |
| Fritsche, HM | 1 |
| Rink, M | 1 |
| Kassouf, W | 1 |
| Spiess, PE | 1 |
| Lotan, Y | 1 |
| Ye, D | 1 |
| Fernández, MI | 1 |
| Kikuchi, E | 1 |
| Chade, DC | 1 |
| Babjuk, M | 1 |
| Grollman, AP | 1 |
| Thalmann, GN | 1 |
1 review available for aristolochic acid i and Colorectal Neoplasms, Hereditary Nonpolyposis
| Article | Year |
|---|---|
Epidemiology, diagnosis, preoperative evaluation and prognostic assessment of upper-tract urothelial carcinoma (UTUC).
Topics: Aristolochic Acids; Carcinoma, Transitional Cell; Colorectal Neoplasms, Hereditary Nonpolyposis; Hum | 2017 |