aristolochic acid i has been researched along with Colonic Neoplasms in 2 studies
aristolochic acid I: phospholipase A inhibitor
aristolochic acid A : An aristolochic acid that is phenanthrene-1-carboxylic acid that is substituted by a methylenedioxy group at the 3,4 positions, by a methoxy group at position 8, and by a nitro group at position 10. It is the most abundant of the aristolochic acids and is found in almost all Aristolochia (birthworts or pipevines) species. It has been tried in a number of treatments for inflammatory disorders, mainly in Chinese and folk medicine. However, there is concern over their use as aristolochic acid is both carcinogenic and nephrotoxic.
Colonic Neoplasms: Tumors or cancer of the COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| "et Zucc (A." | 1.39 | Aristolochia debilis Sieb. et Zucc. induces apoptosis and reactive oxygen species in the HT-29 human colon cancer cell line. ( Li, C; Wang, MH, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Simões, ML | 1 |
| Hockley, SL | 1 |
| Schwerdtle, T | 1 |
| Gamboa da Costa, G | 1 |
| Schmeiser, HH | 1 |
| Phillips, DH | 1 |
| Arlt, VM | 1 |
| Li, C | 1 |
| Wang, MH | 1 |
2 other studies available for aristolochic acid i and Colonic Neoplasms
| Article | Year |
|---|---|
Gene expression profiles modulated by the human carcinogen aristolochic acid I in human cancer cells and their dependence on TP53.
Topics: Apoptosis; Aristolochic Acids; Blotting, Western; Carcinogens; Cell Cycle; Cell Survival; Cluster An | 2008 |
Aristolochia debilis Sieb. et Zucc. induces apoptosis and reactive oxygen species in the HT-29 human colon cancer cell line.
Topics: Apoptosis; Aristolochia; bcl-2-Associated X Protein; Cell Cycle; Cell Line, Tumor; Cell Proliferatio | 2013 |