aristolochic acid i has been researched along with Chemical and Drug Induced Liver Injury, Chronic in 1 studies
aristolochic acid I: phospholipase A inhibitor
aristolochic acid A : An aristolochic acid that is phenanthrene-1-carboxylic acid that is substituted by a methylenedioxy group at the 3,4 positions, by a methoxy group at position 8, and by a nitro group at position 10. It is the most abundant of the aristolochic acids and is found in almost all Aristolochia (birthworts or pipevines) species. It has been tried in a number of treatments for inflammatory disorders, mainly in Chinese and folk medicine. However, there is concern over their use as aristolochic acid is both carcinogenic and nephrotoxic.
Chemical and Drug Induced Liver Injury, Chronic: Liver disease lasting six months or more, caused by an adverse effect of a drug or chemical. The adverse effect may be caused by drugs, drug metabolites, chemicals from the environment, or an idiosyncratic response.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, S | 1 |
| Liu, Z | 1 |
| Wang, Y | 2 |
| Shi, B | 1 |
| Jin, Y | 1 |
| Jiang, X | 1 |
| Song, M | 1 |
| Yu, W | 1 |
1 other study available for aristolochic acid i and Chemical and Drug Induced Liver Injury, Chronic
| Article | Year |
|---|---|
Grape seed extract proanthocyanidin antagonizes aristolochic acid I-induced liver injury in rats by activating PI3K-AKT pathway.
Topics: Animals; Antioxidants; bcl-2-Associated X Protein; Chemical and Drug Induced Liver Injury, Chronic; | 2023 |