aristolochic acid i has been researched along with Carcinoma in 8 studies
aristolochic acid I: phospholipase A inhibitor
aristolochic acid A : An aristolochic acid that is phenanthrene-1-carboxylic acid that is substituted by a methylenedioxy group at the 3,4 positions, by a methoxy group at position 8, and by a nitro group at position 10. It is the most abundant of the aristolochic acids and is found in almost all Aristolochia (birthworts or pipevines) species. It has been tried in a number of treatments for inflammatory disorders, mainly in Chinese and folk medicine. However, there is concern over their use as aristolochic acid is both carcinogenic and nephrotoxic.
Carcinoma: A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chinese herbs nephropathy (CHN) and Balkan endemic nephropathy (BEN) are chronic tubulointerstitial renal diseases associated with urothelial carcinoma." | 1.38 | Chinese herbs nephropathy and Balkan endemic nephropathy: toward a single entity, aristolochic acid nephropathy. ( De Broe, ME, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 8 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, HY | 2 |
| Yang, CC | 1 |
| Wu, CY | 1 |
| Wang, LJ | 1 |
| Lu, KL | 1 |
| Chen, PC | 1 |
| Wang, JD | 1 |
| Kanaan, N | 1 |
| Hassoun, Z | 1 |
| Raggi, C | 1 |
| Jadoul, M | 1 |
| Mourad, M | 1 |
| De Meyer, M | 1 |
| Aydin, S | 1 |
| Schmeiser, HH | 1 |
| Cosyns, JP | 1 |
| Goffin, E | 1 |
| Kucab, JE | 1 |
| Phillips, DH | 1 |
| Arlt, VM | 1 |
| Jelaković, B | 1 |
| Karanović, S | 1 |
| Vuković-Lela, I | 1 |
| Miller, F | 1 |
| Edwards, KL | 1 |
| Nikolić, J | 1 |
| Tomić, K | 1 |
| Slade, N | 1 |
| Brdar, B | 1 |
| Turesky, RJ | 1 |
| Stipančić, Ž | 1 |
| Dittrich, D | 1 |
| Grollman, AP | 2 |
| Dickman, KG | 1 |
| De Broe, ME | 1 |
| Rosenquist, TA | 1 |
| Hawkes, N | 1 |
4 reviews available for aristolochic acid i and Carcinoma
| Article | Year |
|---|---|
Aristolochic Acid and Immunotherapy for Urothelial Carcinoma: Directions for unmet Needs.
Topics: Animals; Aristolochic Acids; Carcinogens; Carcinoma; Humans; Immunotherapy; Urinary Bladder Neoplasm | 2019 |
Chinese herbs containing aristolochic acid associated with renal failure and urothelial carcinoma: a review from epidemiologic observations to causal inference.
Topics: Aristolochic Acids; Carcinogens; Carcinoma; DNA Adducts; Drugs, Chinese Herbal; Female; Humans; Occu | 2014 |
Linking environmental carcinogen exposure to TP53 mutations in human tumours using the human TP53 knock-in (Hupki) mouse model.
Topics: Animals; Aristolochic Acids; Benz(a)Anthracenes; Carcinogens, Environmental; Carcinoma; Environmenta | 2010 |
Mutational signature of aristolochic acid: Clue to the recognition of a global disease.
Topics: Alkylating Agents; Aristolochia; Aristolochic Acids; Carcinogens; Carcinoma; DNA Adducts; DNA Damage | 2016 |
4 other studies available for aristolochic acid i and Carcinoma
| Article | Year |
|---|---|
Long-term Outcome of Kidney Recipients Transplanted for Aristolochic Acid Nephropathy.
Topics: Adult; Aged; Aristolochic Acids; Belgium; Carcinoma; Drug Therapy, Combination; Female; Graft Reject | 2016 |
Aristolactam-DNA adducts are a biomarker of environmental exposure to aristolochic acid.
Topics: Adult; Aged; Aged, 80 and over; Aristolochic Acids; Balkan Nephropathy; Biomarkers; Biotransformatio | 2012 |
Chinese herbs nephropathy and Balkan endemic nephropathy: toward a single entity, aristolochic acid nephropathy.
Topics: Aristolochic Acids; Balkan Nephropathy; Carcinogens, Environmental; Carcinoma; DNA Adducts; Environm | 2012 |
Herbal medicine might be responsible for high incidence of urinary tract cancer.
Topics: Aristolochia; Biomarkers, Tumor; Body Mass Index; Carcinogens; Carcinoma; China; Drugs, Chinese Herb | 2012 |